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> Health COROWISE® PLANT STEROLS COROWISE® PLANT STEROLS Consumers rely on you…you can rely on Cargill While consumers try to pursue a healthy lifestyle for themselves and their families, that may not be enough to maintain ideal cholesterol levels. Cargill’s CoroWise® cholesterol reducer brand of plant sterols offers an additional way to manage cholesterol levels through dietary foods and beverages. Elevated blood cholesterol is a major risk for heart disease, and heart disease is responsible for 50% of all deaths in industrialized countries. However, high blood cholesterol is one health risk factor that can often be modified by lifestyle changes such as diet. Nearly 100 million Americans have elevated cholesterol (>200 mg/dL). Consuming plant sterols as a regular part of a healthy diet provides another option in the maintenance of cardiovascular health. Plant sterol-containing products have been shown to help lower cholesterol in over 40 clinical trials. Blocking cholesterol Nutritional benefits Phytosterols, commonly referred to as plant Plant sterols are compounds that can be consumed sterols, are plant lipids that are present in regularly as part of a healthy diet. Foods such as vegetables, fruits and grains. Just as cholesterol fruits, vegetables, breads and other whole grain is present in all animals, plants have a “sterol” products, and most vegetable oils contain at least of their own acts as a cholesterol blocker. Plant some plant sterols. However, it is difficult to consume sterols’ structure is similar to animal cholesterol, enough of these foods on a daily basis to derive but is not absorbed like cholesterol. When enough plant sterols to have a cholesterol-lowering digesting a meal, plant sterols are believed to effect. Based on the data from scores of trials compete with cholesterol and help to block its conducted on the use of plant sterols in the diet, a absorption. In fact, the efficacy of plant sterols is daily intake of two grams of plant sterols as part of a supported by over 50 years of clinical research diet low in saturated fat and cholesterol is recognized indicating that eating plant sterols can significantly to provide significant cholesterol-lowering benefits. lower LDL cholesterol. Consuming foods with added plant sterols is one way to ensure that an effective daily intake is attained. Plant sterol-containing products have been shown to help lower cholesterol in over 40 clinical trials. Key plant sterols facts Production > Supported by over 50 years of CoroWise® plant sterols are available in several forms, depending upon the food application: clinical research > Shown to significantly reduce bad > Powder forms, multiple granulations (LDL) cholesterol > Sterol esters for oil based application > Supported by a Food and Drug > Aqueous dispersible form. Administration (FDA) health claim Plant sterols are stable across a wide range of > Recommended by the National Cholesterol temperatures and pH levels. Education Program (NCEP) and the National Heart, Lung and Blood Institute of the Typical analysis National Institutes of Health Specifications (Analytical methods available on request) FDA health claim Total Sterols Diets low in saturated fat and cholesterol 94% min. Beta-Sitosterol40-58% that include 2g per day of phytosterols (plant Campesterol20-28% sterols) eaten with meals or snacks may Stigmasterol16-23% reduce the risk of heart disease. A serving of [name of food] supplies _g of phytosterols (plant sterols). APPLICATIONS PRODUCT INFORMATION Broad application opportunities CoroWise® Plant Sterols Code Bakery Baked Goods Cookies Breads Snacks & Cereals Bars Cereals Beverage Dry Mix RTD Confectionary Chews Dairy Beverages Cheese Spreads Yogurt Dietary Supplements Tableting Capsules/Gelcaps FP-100 FP-300 FP-400 SE-C100 • • • • • • • • • ES 200 WDSE 33 • • • • • • • • • • • • • • • • • • • • Fats & Oils Dressings • • • Sauces • • • TRIM LINE Clinical trials with plant sterols magnitude of this benefit, most clinical studies have Clinical evidence has demonstrated that consumption demonstrated an 8-15% reduction in LDL cholesterol. of plant sterols inhibit the intestinal absorption of No adverse clinical effects from the consumption of cholesterol and produce decreases in total blood and plant sterols have been reported. LDL cholesterol. Reductions of blood cholesterol have been demonstrated in normocholesterolemic adults and children, hypercholesterolemic populations, diabetics, in individuals on cholesterol-lowering drugs, familial hypercholesterolemics, as well as in individuals Plant sterols have been evaluated in many different populations, under different circumstances over the past fifty years, and have consistently demonstrated the ability to reduce blood cholesterol in humans. with prior coronary events. The effectiveness of The scientific substantiation supporting the health these substances has been demonstrated when benefits of plant sterols has been well established. incorporated into a variety of different foods including Public health authorities, such as the US National margarines or spreads, mayonnaise, milk, juice, Cholesterol Education Program (NCEP), are beginning supplements, low-fat yogurt, cereal, and bread. to include plant sterols as part of their dietary While there are a number of variables that affect the recommendations (NCEP, 2001). TRIM LINE COROWISE® PLANT STEROLS Brand outreach programs The CoroWise® brand marketing program combines many elements to effectively deliver the CoroWise® brand message. Cobrand partner products are the call to action in all messaging, and are given prominent representation in the following CoroWise® brand outreach activities: > Sponsorships – American Heart Association, Go Red For Women > Tradeshows and Conferences > Direct Marketing > Custom Publication – The Wellness Advisor ® magazine > Consumer Literature and Collateral > Public Relations > Consumer events > Website > Advertising > Speaking Engagements > Spokespeople c o l l a b o r a t e > c r e a t e > s u c c e e d TM As a leading global supplier of health-promoting ingredients for food, beverage, dietary supplement and pharma/personal care industries, Cargill is uniquely positioned to help customers develop exciting new solutions for consumers. Cargill is an international provider of food, agricultural and risk management products and services. With 160,000 employees in 67 countries, the company is committed to using its knowledge and experience to collaborate with customers to help them succeed. Americas Europe, Middle East, Africa Asia Pacific Cargill Health & Nutrition 15407 McGinty Road West Wayzata, MN 55391-2399 USA Tele: +1 866 456 8872 Fax: +1 952 742 1708 Cargill Europe bvba Bedrijvenlaan 9 2800 Mechelen Belgium Tele: +32 15 400 528 Tele: +32 15 401 631 Fax: +32 15 400 591 Cargill Asia Pacific Pte Ltd 300 Beach Road 23-01 The Concourse Singapore 199555 Tele: +65 6295 1112 Fax: +65 6393 8408 www.corowise.com www.cargill.com/food/health www.cargill.com THE INFORMATION CONTAINED HEREIN IS BELIEVED TO BE TRUE AND CORRECT UNDER US LAW. ALL STATEMENTS, RECOMMENDATIONS OR SUGGESTIONS ARE MADE WITHOUT GUARANTEE, EXPRESS OR IMPLIED, AND ARE SUBJECT TO CHANGE WITHOUT NOTICE. WE DISCLAIM ALL WARRANTIES, EXPRESS OR IMPLIED, INCLUDING ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND FREEDOM FROM INFRINGEMENT AND DISCLAIM ALL LIABILITY IN CONNECTION WITH THE USE OF THE PRODUCTS OR INFORMATION CONTAINED HEREIN. © 2014, CARGILL, INCORPORATED. ALL RIGHTS RESERVED. CHN-118NR (2/14)