Download ReseaRch RepoRt - St George and Sutherland Medical Research

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Research
Report
St George and
Sutherland Hospitals
2012 » 2013
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introductions
Professor John Edmonds
Conjoint Professor, UNSW
Chair of the St George and Sutherland Medical Research Foundation
The Research Report of the St George and Sutherland Hospitals, currently published every second year, is an important
record of our clinical and research staff and some traditional indicators by which institutions’ research status is judged:
projects undertaken, grants awarded, publications and presentations. There are encouraging pointers, great and small,
that government and society are increasingly recognising the importance of medical research: McKeon’s Strategic Review
of Health and Medical Research; a federal commitment to a 20 billion dollar medical research fund; the choice of Suzanne
Corey (former Director of WEHI) as the 2014 Boyer Lecturer; even a recent Q & A session devoted to Science & Australia.
As society looks to its great academic medical centres for research-driven guidance, it becomes ever more important that
St George and Sutherland Hospitals match the excellence of their clinical service and teaching with a comparable level of
eminence in research endeavour and success. The St George and Sutherland Medical Research Foundation is committed
to helping the hospitals’ academics in that project. The Research Reports provide a useful audit of our joint progress.
Professor Peter Gonski
Head, Sutherland Teaching Unit
St George Clinical School
Although Sutherland Hospital is well known as a provider of major clinical service to the South Eastern Sydney Local
Health District, it also provides a major teaching resource to medical, nursing and allied health students. Research is now
becoming important in its activities. On behalf of Sutherland, I am grateful that the St George and Sutherland Medical
Research Foundation has included us in their activities and also providing research funds. With the close relationships
between the hospital, community, Universities and Foundation, which have already been secured, I can only see the
research interest increase in the future. I do think that our significant clinical load allows us to be leaders in clinical research
and assure that our research will directly influence patient care and lives. It is wonderful to have our research celebrated in
this report.
Professor Ritin Fernandez
Professor of Nursing
Research and Innovation is vital to the provision of quality healthcare for our patients. At St George Hospitals clinician
and scientists undertake the full spectrum of basic biomedical, clinical and health services research. There has been a
remarkable progress in research outputs and outcomes at St George Hospital and this report high lights the unique and
influential research that is being conducted by our world class researchers. The report also demonstrates the commitment
of researchers and scientists not only towards evidence synthesis but also in translating and implementing the evidence in
clinical practice.
I would like to acknowledge the role and contribution of the broader hospital community, our patients, the many
volunteers, our collaborators and supporters, particularly the St George and Sutherland Medical Research Foundation
without whom research here would not be possible. The research achievements are very encouraging, but more
importantly they form the foundation for future research endeavours as well as provide inspiration and motivation as we
move forward.
Professor Michael Grimm
Clinical Associate Dean
St George Clinical School, UNSW
Research in our hospitals fundamentally supports the excellence in clinical care for which we all strive. If anything,
this will become even more important in coming years. This important report demonstrates the extraordinary breadth
and impressive depth of research activities undertaken at St George and Sutherland Hospitals, and I hope it serves to
announce those achievements loudly and emphatically.
The composing of a document such as this always comes as a surprise: surprise at the breadth and volume of research
carried out by hospital and university staff and students, from most senior to undergraduate levels. It’s a testament to the
enormous amount of hard work that goes into making our hospitals vital and inquiring places, as well as places of healing.
I commend this report to all members of our hospital communities.
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Contents
Medicine And Critical Care
5
Mental Health
109
Cardiology
6
Dermatology
8
Mental Health Academic Unit, School of
Psychiatry
110
Women’s and Children’s Health
115
Emergency – St George Hospital
15
Emergency – The Sutherland Hospital
18
Endocrinology
19
Urogynaecology
116
Gastroenterology and Hepatology
22
Women’s Health
119
Infectious Disease, Immunology and
Sexual Healh
27
Nursing and Midwifery
127
Intensive Care – St George Hospital
31
Nuclear Medicine
41
Centre for Research in Nursing and Health
128
Renal Medicine
42
Respiratory and Sleep Medicine
47
136
Rheumatology
49
South Eastern Sydney Laboratory
Services
Anatomical Pathology
137
Aged and Extended Care
139
Cancer Services
52
Haematology
53
Medical Oncology
61
Aged Care St George Hospital
140
Palliative Care
69
Rehabilitation Medicine
141
Radiation Oncology
79
Southcare The Sutherland Hospital
142
Surgery, Perioperative And Anaesthetic
Services
82
Allied Health
143
Anaesthesia
83
Nutrition and Dietetics
144
Cardiothoracic Surgery
85
Occupational Therapy
146
Liver and Periotonectomy Surgery
90
Physiotherapy
147
Orthopaedic Surgery
96
Speech Pathology
148
Erratum
151
Trauma
104
Vascular Surgery
108
MEDICINE AND
CRITICAL CARE
Cardiology
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6
Renal Medicine
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42
Dermatology
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8
Respiratory Medicine
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47
Emergency –
St George Hospital
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15
Rheumatology
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49
Emergency –
Sutherland Hospital
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18
Endocrinology
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19
Gastroenterology and
Hepatology
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22
Infectious Disease,
Immunology and Sexual
Health
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27
Intensive Care –
St George Hospital
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31
Nuclear Medicine
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41
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Department of Cardiology
Head of Department
Dr Mark Sader MBBS(Hons) PhD
Senior Medical - Staff Specialists
Dr David Ramsay
Dr David Rees
Dr Andrew Hopkins
Dr Maurits Binnekamp
Dr Ananth Prasan
Dr George Youssef
Dr James Weaver BSc Med MBBS(Hons) PhD
Dr Queenie Lo
Dr Victar Hsieh
Research Staff
Deborah Vrachas – CNS
Glenn Paull - CNC
Research Projects in Progress
A bone marrow-derived Stro3 mesenchymal precursor
cells (MPC) in the treatment of patients with ST-elevation
myocardial infarction, Dr. Ananth Prasan.
A Double-blind, Randomized, Placebo-controlled,
Multicenter Study Assessing the Impact of Additional
LDL-Cholesterol Reduction on Major Cardiovascular
Events When AMG 145 is Used in Combination With Statin
Therapy In Patients with Clinically Evident Cardiovascular
Disease, Dr. Ananth Prasan.
Prevention of contrast-induced acute kidney injury In
people undergoing angiogram, Dr. Ananth Prasan.
TIGRIS Study data collection 1-3yr post MI patients, Dr
Mark Sader
Study to evaluate Cardiovascular Outcomes Following
Treatment with study drug in Addition to Standard of Care
in Subjects with Type 2 DM and ACS, Dr. Ananth Prasan.
Thromectomy VS PCI alone in STEMI patients, Dr James
Weaver.
The Advisa MRI System study is a prospective, randomised
controlled, non-blinded, multi centre worldwide
investigational study, Dr Andrew Hopkins.
To confirm safety and effectiveness of the Model 5076
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Lead in the clinical MRI (Magnetic Resonance Imaging)
environment, Dr Andrew Hopkins.
A Multicentre, Randomised, Double blind, PlaceboControlled Study to Evaluate the Safety and Efficiency of
study drug in Addition to Standard of Care in subjects with
Acute Coronary Syndrome. Thrombin Receptor Antagonist
in Acute Coronary Syndrome, Dr Ananth Prasan.
A Phase 3, Randomised, Double-Blind, Evaluation of the
Safety and Efficiency of study drug In Subjects with a
recent ACS, Dr. Ananth Prasan.
Trial Evaluating CV Outcomes with study drug in patients
with Type 2 Diabetes, Dr. Maurits Binnekamp.
A randomized, double-blind, placebo-controlled, event
driven trial of quarterly subcutaneous canakinumab in
the prevention of recurrent cardiovascular events among
stable post-myocardial infarction patients with elevated
hsCRP, Dr George Youssef.
Original Peer-Reviewed Publications
Rayner BS, Figtree GA, Sabaretnam T, Shang P, Mazhar J,
Weaver JC, Lay WN, Witting PK, Hunyor SN, Grieve SM,
Khachigian LM, Bhindi R. Selective Inhibition of the Master
Regulator Transcription Factor Egr-1 Using Catalytic
Oligonucleotides Reduces Myocardial Injury and Improves
Left Ventricular Systolic Function in a Preclinical Model
of Myocardial Infarction. Journal of the American Heart
Association. 2013; 2 (4):e000023. PMID 23902638.
Sorensen R, Paull G, Magaan L, Davis JM (2013).
Managing between the agendas - implementing health
care reform policy in an acute care hospital. Journal of
Health Organization and Management; 27 (6) 698-713.
Presentations at Scientific Meetings and
Conferences
2012 International
Sorensen R, Paull G, Magaan L, Davis JM. Is poor quality
of care built into the system? Evidence from a study on
communication among teams treating people dying in
hospital wards. 8th International Organisational Behaviour
in Healthcare Conference - Patient-centred healthcare
teams: achieving collaboration, communication and care.
Dublin, Ireland.
2012 National
Paull G, Gallagher R, Horvath R, Chen D. Discrimination
and high sensitivity cardiac troponin: the relationship
between clinical presentation, clinical request and
discharge diagnosis. 60th Annual Scientific Meeting of
Cardiac Society of Australia and New Zealand, Brisbane.
Chandrasekhar J, Paull G, Youssef G, Weaver J, Rees D.
Single Centre Clinical Experience and Discharge planning
using high sensitivity troponin T post Elective PCI. 60th
Annual Scientific Meeting of Cardiac Society of Australia
and New Zealand, Brisbane.
Davis S, Paull G, Vuong N, Connolly B, Ang E. ICD’s and
PTSD: a shocking story - from crisis to recovery. Australian
Cardiovascular Health and Rehabilitation Association
Annual Conference, Brisbane.
Paull G. Chronic Disease Self-management: Multilingual
Audiovisual Resources for People with Ischaemic
Heart Disease and Chronic Heart Failure. Australasian
Cardiovascular Nursing College Annual Scientific Meeting,
Sydney.
2013 National
Arndt M, Paull G. Living Well with Heart Failure: a role for
Occupational Therapy in the management of chronic heart
failure. Australian Cardiovascular Health & Rehabilitation
Association Annual Scientific Meeting – Melbourne.
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Department of Dermatology
Head of Department
2012-Jan 2013
Julie Dandenooy, Medical resident, Antwerp University,
Belgium, Oct-Nov 2012; now Dermatology registrar
*Dedee F Murrell MA(Cambridge) BMBCh (Oxford) FAAD
(USA) MD (UNSW) FACD
Conjoint Professor, Faculty of Medicine UNSW
Research Staff/Students Supervised
Senior Medical
Senior
Visiting Medical Officers
*Anthony J Cronin MBBS (Syd) PhD (Cambridge) FACD
*Mei-Heng Tan MBBS (Syd) FAAD (USA)
Lizbeth Ruth A Intong MD FPDS Post dermatology
research fellow; now FACD
Sabbaticals
M.Tariq Khan PhD (London) M Pod (UK), from Great
Ormond St Hospital, Visiting Fellow, UNSW 2011-14
Research Fellows
Dr Clarisse G Mendoza (Honorary VMO and Research
Fellow
Mae Ramirez MD FBDS (Honorary VMO and Research
Fellow
Jaehwan Kim MD PhD (Honorary VMO and Research
Fellow
Joni Lazo Dizon MD FPDS (Honorary VMO and Research
Fellow
Junior
Benjamin S Daniel B.Com, MBBS- Predermatology
research fellow-2011-12
Research Students
Wenfei Yan MD China- completed PhD (UNSW) 2012; post
Doc 2013;
Supriya Venugopal MBBS – p/t PhD student;
Heather Cohn, MD PhD Postdoc on America Australia
Association grant
Clement Loh (Honours research student)- High distinction
Nursing Research
CNC for Epidermolysis Bullosa
Lesley M Rhodes RN
Jackie Cochrane RN
Charmaine Peras RN
Lesley M Rhodes RN
Margaret Norris RN Independent Learning Project Students
*Unaccredited dermatology registrars:
Bonnie Fergie MBBS (UWA) 2012
Robert George MBBS (Otago) M Surg (U Syd) 2013
Jessica Davey
Anh Tran (distinction)
Charles Wang
*Funded by St George Hospital; rest from external
sources.
Visiting Dermatologists to St George/Premier Specialists
Research Grants
William Hoang, Wake Forest University, NC, USA, 2012
(WDS grant)
Nancy Todes Taylor, San Francisco, Kaiser Permanente
2012
NHMRC Project Grant: Investigation of flightless-1 in
epidermolysis bullosa. Allison Cowin, Ruth Arkell, Dedee
Murrell. $517,500, 2009-12.
Junior Medical
Visiting Dermatology Mentee Observers
Michele Ramien, Derm Registrar, Univ of Ottawa, Jan-Feb
2012
Sang Hee Lee, Derm Registrar, Yonsei University College
of Medicine, Seoul, Korea, May 2012
Herm Maartens, Derm Registrar, Masstricht University, Oct
8
Grant from DebRA Australia, Dedee Murrell. $12,000,
2012/2013.
Grant for Biologics Clinic, Abbott Pharmaceuticals, Dedee
Murrell , $15,000, 2012/2013.
Donation for EB Research from Caroline Quinn Trust Fund,
Dedee Murrell $25,000, 2012/2013.
Research Projects in Progress
Responsiveness of a quality of life instrument for
autoimmune blistering diseases, the ABQOL we
developed; Dedee Murrell, Renette Ang, Melanie Doria,
Cathy Zhao.
International validation of the QOLEB, the qualify of life
measure we developed and published for Australian
patients with EB; Dedee Murrell and various international
investigators.
Outcomes of pregnancies in EB; Murrell DF, Intong LRA,
Choi DS, Rhodes LM, Walton J, Chapman M.
Role of flightless-1 in EB and EBA; Kopecki Z, Murrell DF,
Cowin, A.
AIBD Registry; Dermawan A, Intong LRA, Murrell DF.
Epidemiology of Anaemia in EB; Hwang S, Daniel BF,
Murrell DF.
Epidemiology of renal impairment in EB; Murrell DF.
Original Peer-Reviewed Publications
Intong LRA, Murrell DF: Inherited EB: New diagnostic
criteria and classification. Clin Dermatol. 2012 JanFeb;30(1):70-7. doi: 10.1016.
Sarig O, Bercovici S, Zoller L, Goldberg I, Indelman M,
Nahum S, Israeli S, Sagiv N, Martinez de Morentin H, Katz
O, Baum S, Barzilai A, Trau H, Murrell DF, Bergman R,
Hertl M, Rosenberg S, Nöthen MM, Skorecki K, Schmidt
E, Zillikens D, Darvasi A, Geiger D, Rosset S, Ibrahim SM,
Sprecher E. Population-Specific Association between a
Polymorphic Variant in ST18, Encoding a Pro-Apoptotic
Molecule, and Pemphigus Vulgaris. J Invest Dermatol.
2012 Mar 22. doi: 10.1038/jid.2012.46
Venugopal SS, Murrell DF. Diagnosis and clinical features
of pemphigus vulgaris. Immunol Allergy Clin North Am.
2012 May;32(2):233-43.
Frew JW, Murrell DF. Corticosteroid use in AIBD. Immunol
Allergy Clin North Am. 2012 May;32(2):283-94.
Chee SN, Murrell DF.Use of Intravenous immunoglobulin
in autoimmune blistering diseases. Immunol Allergy Clin
North Am. 2012 May;32(2):323-30.
Daniel BS, Murrell DF, Joly P. Rituximab and its use in
autoimmune blistering disorders. Immunol Allergy Clin
North Am. 2012 May;32(2):331-7.
Murrell DF Autoimmune diseases of the skin. Immunol
Allergy Clin North Am. 2012 May;32(2):xiii-xiv.
Ng YZ, Pourreyron C, Salas-Alanis JC, Dayal JH, CepedaValdes R, Yan W, Wright S, Chen M, Fine JD, Hogg FJ,
McGrath JA, Murrell DF, Leigh IM, Lane EB, South AP.
Fibroblast-derived dermal matrix drives development of
aggressive cutaneous squamous cell carcinoma in patients
with recessive dystrophic epidermolysis bullosa. Cancer
Res. Jul 15;72(14):3522-34, 2012.
Wriston CC, Rubin AI, Martin LK, Kossard S, Murrell DF.
Plaque like cutaneous mucinosis. Am J Dermatopathol.
2012 Jun;34(4):e50-4.
Daniel BS, Murrell DF. Intravenous immunoglobulin:
recent advances in the treatment of autoimmune bullous
diseases. J Ital Dermatol Venereol. 2012 Jun;147(3):25967.
Hwang S, Kim MH, Kemble Welch A, Hanley MC, Murrell
DF. Volunteering at an adventure camp for epidermolysis
bullosa. Med J Aust. 2012 2012 Jul 5;197(1):54.
Schmitt J, Spuls P, Boers M, Thomas K, Chalmers J,
Roekevisch E, Schram M, Allsopp R, Aoki V, Apfelbacher
C, Bruijnzeel-Koomen C, Bruin-Weller M, Charman C,
Cohen A, Dohil M, Flohr C, Furue M, Gieler U, Hooft
L, Humphreys R, Ishii HA, Katayama I, Kouwenhoven
W, Langan S, Lewis-Jones S, Merhand S, Murota H,
Murrell DF, Nankervis H, Ohya Y, Oranje A, Otsuka H,
Paul C, Rosenbluth Y, Saeki H, Schuttelaar ML, Stalder
JF, Svensson A, Takaoka R, Wahlgren CF, Weidinger S,
Wollenberg A, Williams H. Towards global consensus on
outcome measures for atopic eczema research: results of
the HOME II meeting. Allergy. Sep;67(9):1111-7, 2012.
Daniel BS, Skowronski G, Myburgh J, Hersch M, Murrell
DF. Concurrent Management of Toxic Epidermal Necrolysis
with Thermal Water Spray and non-stick dressings. Acta
Dermatol Croat; 20(3):210-212,2012.
Sebaratnam DF, Venugopal SS, Frew JW, McMillan JR,
Finkelstein ER, Martin LK, Murrell DF. Diffuse melanosis
cutis: a systematic review of the literature. J Am Acad
Dermatol.
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2012 Dec 5. doi:pii: S0190-9622(12)00901-2. 10.1016/j.
jaad.2012.08.018.1.
Kopecki Z, Ruzehaji N, Turner C, Iwata H, Ludwig RJ,
Zillikens D, Murrell DF, Cowin AJ. Topically applied
Flightless I neutralising antibodies improve healing of
blistered skin in a murine model of epidermolysis bullosa
acquisita. J Invest Dermatol 6th Dec 2012 doi:10.1038/
jid.2012.457.
Chow HT,Tran K, Millar E, Lynch J, Murrell DF. Diverse
Presentations of Carcinoma Erysipelatoides to a teaching
hospital in Australia. Case Reports in Dermatological
Medicine. 2012;2012:134938. doi: 10.1155/2012/134938.
Epub Dec 23.
Kim MH, Li M, Intong LRA,Tran K, Melbourne W, Marucci
D, Bucci J, de Souza P, Mallesara G, Murrell DF: Use of
cetuximab as an adjuvant agent to radiotherapy and
surgery in Recessive Dystrophic Epidermolysis Bullosa with
Squamous Cell Carcinoma. Br J Dermatol 2013 Feb 12.
doi: 10.1111/bjd.12272.
Ramirez M, Murrell DF, Fine JD. Management of
Epidermolysis Bullosa Exp Opin Orph Drugs. Apr 2013,
Vol. 1, No. 4, Pages 279-293.
Daniel BS, Murrell DF, Borradori L. Management of Bullous
Pemphigoid. Exp Opin Orph Drugs. May 2013, Vol. 1, No.
5, Pages 405-412.
Tong PL, Qin J, Cooper CL, Lowe PM, Murrell DF,
Kossard S, Ng LG, Roediger B, Weninger W, Haass NK. A
quantitative approach to histopathological dissection of
elastin-related disorders using multiphoton microscopy. Br
J Dermatol. 2013 May 11. doi: 10.1111/bjd.12430.
Daniel BS, Murrell DF. Complete resolution of chronic
multiple verruca vulgaris treated with quadrivalent
human papillomavirus vaccine. JAMA Dermatol. 2013
Mar;149(3):370-2. doi: 10.1001/jamadermatol.2013.1463.
Kim J, Loh CH, Murrell DF. Epidermolysis bullosa
pruriginosa triggered by scabies infestation J Dermatol.
2013 May 10. doi: 10.1111/1346-8138.12167.
Murrell DF: The pitfalls of skin biopsies for the diagnosis
of epidermolysis bullosa Pediatr Dermatol. 2013 MarApr;30(2):273-5. doi: 10.1111/pde.12095
Sebaratnam DF, Hanna AM, Chee SN, Frew JW,
Venugopal SS, Daniel BS, Martin LK, Rhodes LM, Tan JC,
Wang CQ, Welsh B, Nijsten T, Murrell DF. Development
of a Quality-of-Life Instrument for Autoimmune Bullous
Disease: The Autoimmune Bullous Disease Quality of Life
Questionnaire.JAMA Dermatol. JAMA Dermatol. 2013
Oct;149(10):1186-91.
Frew JW, Cepeda-Valdes R, Fortuna G, Murrell DF,
Salas-Alanis J: Measuring Quality of Life in Epidermolysis
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Bullosa in Mexico: Cross Cultural Validation of the Hispanic
Version of the Quality of Life in Epidermolysis Bullosa
Questionnaire. J Am Acad Dermatol 2013 69(4) 652-63.
Venugopal SS, Yan W, Frew JW, Cohn HI,Rhodes LM,
Tran K, Melbourne W, Nelson JA, Sturm M, Fogarty J,
Marinkovich MP, Igawa S, Ishida-Yamamoto A, Murrell
DF. A phase II randomized vehicle controlled trial of
intradermal allogeneic fibroblast therapy for recessive
dystrophic epidermolysis bullosa. J Am Acad Dermatol
Sep 24 2013. doi:pii: S0190-9622(13)00864-5. 10.1016/j.
jaad.2013.08.014 .
Tjokrowidjaja A, Daniel BS, Frew JW, Sebaratnam DF,
Hanna AM, Chee SN, Dermawan A, Wang CQ, Lim C,
Venugopal SS, Rhodes LM, Welsh B, Nijsten T, Murrell
DF. The development and validation of the TABQOL, a
tool to measure the quality of life impacts of treatments
used in patients with autoimmune blistering disease. Br
J Dermatol published online 31 Oct 2013 DOI: 10.1111/
bjd.12623 with accompanying editorial by Andrew Finlay
mentioning its significance.
Loh CH, Kim J, Su JC, Daniel BS, Venugopal SS, Rhodes
LM, Intong LRA, Law MG and Murrell DF. Development,
Reliability and Validity of a novel Epidermolysis Bullosa
Disease Activity and Scarring Index (EBDASI). J Am Acad
Dermatol 2014 Jan;70(1):89-97.
Brennan F, Murrell DF: Report from the Inaugural Pruritus
Symposium, Sydney, Australia, 10th August 2013. Acta
Derm Venereol. 2013 Oct 24. doi: 10.2340/000155551732.
Sebaratnam DF, Venugopal SS, Murrell DF: Development
of an excel spreadsheet to document activity in
autoimmune bullous diseases. Acta Dermatovenerol Croat.
2013 Oct;21(3):207-8.
Dayal J, Cole C, Pourreyron C, Watt S, Lim Y, Salas-Alanis
J, Murrell DF, McGrath J, Steiger B, Jahoda C, Leigh
I, and South AP. Type VII collagen regulates tumour
expression of organic anion transporting polypeptide
OATP1B3, promotes front to rear polarity and increases
structural organisation in 3D spheroid cultures of recessive
dystrophic epidermolysis bullosa tumour keratinocytes. J
Cell Sci (Dec 2013 e pub).
Murrell DF, Amagai M, Werth VP: Why bother with scoring
systems for blistering diseases in practice and which one
should you use? Invited editorial. JAMA Dermatol 2014
Jan 15. doi: 10.1001/jamadermatol.2013.8179.
Yuen QY, Frew JW, Veerman K, Van den Heuvel ER,
Murrell DF, Jonkman MF: Health related quality of life in
epidermolysis bullosa: validation of the Dutch QOLEB
Questionnaire and assessment in the Dutch population.
Acta Derm Venereol 2013 Dec 12. doi: 10.2340/0001555517582013.
Kopecki Z, Yang GN, Arkell RM, Jackson JE, Melville
E, Iwata H, Ludwig RJ, Zillikens D, Murrell DF, Cowin
AJ: Flightless I overexpression impairs skin barrier
development, function and recovery post skin blistering. J
Pathol Dec 28, 2013 e pub. DOI 10.1002/path 4323.
Other published material
Up to date: DF Murrell invited author for 4 chapters, 2012,
with biannual updates:
Murrell, DF. ICD-11 – section on definitions and
descriptions of Epidermolysis Bullosa 2012
Murrell, DF, Textbook: Blistering Diseases. Springer Verlag.
In process, 2013.
Murrell DF, Cases in Blistering Diseases. Elsevier, book,
2013.
Daniel BS, Murrell DF. Epidermolysis Bullosa. In: Clinical
Genomics: Practical Applications in Adult Patient Care.
McGraw Hill and American College of Physicians, 2013,
chapter 110.
Sebaratnam DF, McMillan JR, Werth V, Murrell DF: Quality
of life in patients with bullous dermatoses. Clinics in Derm
Jan;30(1):103-7. doi: 10.1016/j.clindermatol.2011.03.016.,
2012.
Daniel BS, Hertl M, Werth VP, Eming R, Murrell
DF: Severity Score Indexes for blistering
diseases. t, Jan;30(1):108-13, 2012 doi: .1016/j.
clindermatol.2011.03.017.
Kim MH, Intong LRA, Murrell DF: Epidermolysis bullosa
and squamous cell carcinoma. In: Squamous Cell
Carcinoma, Editor: Daniel V. Mortensen. Nova Publishers,
Ch 5:107-122, 2012. ISBN: 978-1-61209-929-3.
Fergie BF, Intong LRA, Murrell DF: Management
strategies for epidermolysis bullosa acquisita. In Update
in dermatologic drug therapy, edited by Jasna Lipozencic.
Published by the Academy of Medical Sciences of Croatia,
Zagreb, 2012. ISBN 978-953-6868-39-1. Chapter 21, pp
245-253.
Frew JW, Murrell DF: An update on the use of
corticosteroids in autoimmune blistering diseases. In
Update in dermatologic drug therapy, edited by Jasna
Lipozencic. Published by the Academy of Medical
Sciences of Croatia, Zagreb, 2012. ISBN 978-953-6868-391. Chapter 22, pp 254-268.
Loh CH, Kim J, Murrell DF: Urticaria. In: Australian Doctor
How to Treat Yearbook 2013, pp 213-218. Editor: S. Liang.
Publisher: Craft Print, Singapore.
Presentations at Scientific Meetings and
Conferences
2012
Professor D. Murrell
American Academy of Dermatology, San Diego, March
2012, Autoimmunity forum – what’s new in autoimmune
bullous diseases - invited lecture
Stanford University – Epithelial Biology Marinkovich Lab,
March 2012, Allogeneic cultured fibroblast therapy for
recessive dystrophic epidermolysis bullosa - invited lecture
American Academy of Dermatology, Boston, MA, August
2012, Forum on AIBD – Complex cases - invited lecture
NSW Dermatology Nurses Association, August 2012,
Management of autoimmune blistering diseases- invited
lecture
GP education evening, St George Area, August 2012. Skin
manifestations of systemic disease. 80 GPs. Sponsored by
Stiefel/GSK - invited lecture
Continental Congress of Dermatology, Durban, South
Africa, Oct 2012, 3 invited lectures
Management of lupus in women – Maria Duran
sympsosium - Epidermolysis Bullosa – what’s new?
Pemphigoid – what’s new?
American Academy of Dermatology, San Diego, CA,
March 2012
Chair, Forum on Management of Epidermolysis Bullosa
Speaker - Pathogenesis of squamous cell carcinoma in EB
Speaker - What’s new in autoimmune blistering diseases.
Co-chair, First Inernationall Consensus meeting on EBA
3rd World Congress of Dermoscopy – Brisbane, QLD, May
2012. Chair, Women’s Dermatologic Society networking
reception.
Australasian College of Dermatologists Meeting, Brisbane,
QLD, May 2012
Plenary speaker – ERIVANCE phase II trial for advanced
BCC
Speaker - Consensus definitions and scoring for Bullous
Pemphigoid.
American Academy of Dermatology Summer Meeting,
Boston, Aug 15-19, 2012
Chair- Forum on Difficult cases in bullous diseases
Continental Congress of the International Society of
Dermatology, Durban, S. Africa, Oct 25-29, 2012.
Chair, Blistering Diseases Symposium
Speaker, Paediatric Dermatology – what’s new in EB
therapies
Speaker, Maria Duran Symposium- Management of lupus
in women and children.
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Grading of Registrar presentations & presentation of
awards at opening ceremony
treatment of Pemphigus, Shiraz University Hospital- 17th
June.
Epidermolysis triennial research conference (invitation
only); Marbella, Spain, Nov 4-7, 2012. Invited speaker –
scoring systems for EB
3rd Munich International Summer Academy of Practical
Dermatology, July 2013
Invited speaker – diagnosis and management of lupus
(plenary)
WDS speaker - hedgehog inhibitors for advanced and
metastatic BCC.
Australasian Society for Dermatological Research, Sydney,
NSW May 22-24, 2012
Murrell DF, Convenor of the ASDR conference
Venugopal S, Yan WF, Frew JW, Murrell DF: Randomized
controlled trial of cell therapy for RDEB.
Venugopal SS, Rhodes LM, Welsh B, Nijsten T, Murrell DF:
Validation of a the psychometric properties of a quality of
life measure specific to autoimmune bullous disease.
Kim MH, Li M, Intong RA, Tran K, Melbourne W, Marucci
D, Inder S, Bucci J, De Souza P, Mallesara G, Murrell DF:
Use of cetuximab as an adjuvant agent to radiotherapy
and surgery in Recessive Dystrophic Epidermolysis Bullosa
with Squamous Cell Carcinoma.
2013
Professor D. Murrell
American Academy of Dermatology, Miami, USA, March
2013
Chair, EB Management Forum; speaker on EB and
squamous cell carcinoma
Speaker - Biologics beyond psoriasis forum – rituximab
Speaker – cell therapy for epidermolysis bullosa
Speaker – what’s new in epidermolysis bullosa.
Israeli Dermatology Society, Tel Aviv, April 24-26, 2013
Invited keynote Speaker –plenary lecture- Evidence based
treatment of AIBD.
Bullous Disease Research meeting, Lubeck, Germany:
Speaker - Scoring systems for AIBD;
Speaker - Consensus conference on EBA.
World Congress of Paediatric Dermatology, Madrid, Spain,
Sept 25-29, 2013
Invited Chair – blistering diseases in children
Speaker – neonatal autoimmune blistering disorders
Poster- validation of QOLEB in Brazilian Portuguese & of
EBDASI.
European Academy of Dermatovenereology, Istanbul,
Turkey, Oct -4-7, 2013
Chair- autoimmune blistering diseases
Speaker – Collagen VII spectrum disorders
Speaker - Validation of EBDASI scoring system
Co-Chair- Women’s Dermatologic Society Rose Parade of
Cases
World Congress – International Society of Dermatology,
New Delhi, India, Dec 2013
Co-Chair & Speaker, Autoimmunity Symposium
Invited Speaker, What’s New in treatment of genetic skin
diseases
Member of the Scientific Committee
Co-Chair, Women’s Dermatologic Society Rose Parade of
Cases
R. N. T Medical college, Udaipur,Rajasthan, India,
December 12th, 2013, invited by Dr Asit Mittal, Evidence
based treatment of pemphigus.
Collaborative Presentations
International Investigative Dermatology, Edinburgh, May
2013
Australasian Society for Dermatology Research, Sydney,
May 2013 Speaker - Translational therapies for EB
Speaker - Interim results from the STEVIE trial for
advanced and metastatic BCC.
Loh CH, Kim J, Su J, Daniel BS, Venugopal SS, Rhodes LM,
Law M, Murrell DF. Development, Reliability and Validity
of a Novel Severity Score for Epidermolysis Bullosa: the
Epidermolysis Bullosa Disease Activity and Scarring Index
(EBDASI) (Presented by Clement Loh, Student).
Australasian College of Dermatologists, Sydney, May 2013
Speaker – Understanding hedgehog inhibitors for
advanced and metastatic basal cell carcinomas.
Tran AQT, Lazo-Dizon JP, Kim J, Daniel BS, Venugopal SS,
Rhodes LM, Law MG, Murrell DF. Reliability study of four
objective outcome measures for atopic dermatitis.
Iranian Society of Dermatology, (Profs Dowlati & ChamsDavatchi) June 2013- invited lectures
University of Tehran, Research Institute of Dermatology,
What’s New in EB? 11th June
Evidence Based treatment in AIBD, Razi Hospital. 12th
June
Novel Specific Therapies for EB & Evidence based
Yan WF, Venugopal SS, Frew JW, Rhodes LM,, Melbourne
W, Tran K, Murrell DF. Translocation of the cytokine
HMGB1 coincides with wound healing in fibroblastinjected wounds of Recessive Dystrophic Epidermolysis
Bullosa.
12
Kopecki Z, Yang GN, Arkell RM, Jackson JE, Iwata
H, Ludwig RJ, Zillikens, D, Murrell DF and Cowin
AJ. Flightless I overexpression impairs skin barrier
development, function and recovery post-blistering.
Tjokrowidjaja A, Daniel BS, Frew JW, Sebaratnam DF,
Hanna AM, Chee S, Dermawan A, Wang CQ, Lim C,
Venugopal SS, Rhodes LM, Cochrane J, Welsh B, Nijsten
TM, Murrell DF. The development and validation of the
TABQOL, a tool to measure the quality of life impacts of
treatments used in patients with autoimmune blistering
disease.
Australasian College of Dermatologists, Sydney, May 2013
Hwang SJ, Daveys J, Fergie B, Rhodes LM, Daniel BS,
Murrell DF. Prevalence and characterisation of anaemia in
patients with Epidermolysis Bullosa registered in Australia.
Loh CH, Kim J, Su J, Daniel BS, Venugopal SS, Rhodes LM,
Law M, Murrell DF. Development, Reliability and Validity
of a Novel Severity Score for Epidermolysis Bullosa: the
Epidermolysis Bullosa Disease Activity and Scarring Index
(EBDASI) (Presented by Clement Loh, Student).
Frew JW, Cepeda-Valdes R, Fortuna G. Salas-Alanis JC,
Murrell DF. Cross Cultural Adaptation of the “Quality of
Life in Epidermolysis Bullosa” (QOLEB) Questionnaire:
Validation and Results of Hispanic Translations.
Community Engagement
Australasian Blistering Diseases Foundation – Patient
support group meetings organized on St George Campus
and fundraising to support research into life threatening
blistering diseases.
DebRA Australia – annual meeting in Melbourne to assist
EB patients attending.
Butterfly Day – fundraising for DebRA –front lobby of St
George Hospital.
Prof D. Murrell – seeing patients with blistering diseases
and teaching abroad
HKL, UPM, Islamic University, Kuala Lumpur, Malaysia - 4
weeks
Medical mission to see patients and teach medical staff
about Epidermolysis Bullosa in Vietnam: FV Hospital,
Ho Chi Min & National Paediatric Hospital, Hanoi,
accompanied by EB nurse.
Arranged visiting apprenticeship for Dr Thach Hoang,
Pathologist, National Pediatric Hospital, Hanoi, Vietnam,
to learn immunofluorescence mapping of Epidermolysis
Bullosa.
Interviews with Media
Front cover of Rotary Down Under Jan 2012 Issue 535:
More than skin deep, about our EB mission to Vietnam.
Interview for “Tonic” on ABC TV news segment in health
report by Dr Norman Swan, regarding medical spa therapy
for atopic eczema, 8th Jan 2012.
Interview for A Current Affair on Channel 9, on the new
oral drug for basal cell skin cancer, Erivedge, due to the
clinical trial we conducted and an interview of one of my
trial patients. Thursday February 2nd, 6.45pm, 2012.
Conferences and Seminars Organized - Professor D.
Murrell
Australasian Society for Dermatological Research
Conference, Dockside Conference Centre, Darling
Harbour, May 22-24th, Sydney 2012, 250 registrants.
8 international speakers. Fundraised for the meeting.
Scientific program co-chair. International Society of Dermatology – Continental
Congress. Durban, South Africa. Member of the Scientific
Committee. Oct 2 27th, 2012.
First Australasian Pruritus Conference, Aug 19th, St
George Hosp, Sydney, with Dr Frank Brennan.
International Society of Dermatology- World Congress.
New Delhi, India. Member of Scientific Committee. Dec
4-7th, 2013.
2013 Secured bid for Australia to host the 2021,
International Congress of Dermatology, as Congress
President, Int’l Society of Dermatology, Melbourne,
Australia, November 2021. (successful bid, in India, ICD
2013)
Grant Reviewer - Prof DF Murrell, 2012-13
Ludwig Boltzmann Gesellschaft, Austria – up to $1M Euros
United States-Israel Binational Science Foundation 2011,
grants up to $500K
St George Hospital Medical Research Foundation 2012,
2013
University of Modena – Reggio Emilia 2012
PSI Foundation, Canada 2012
Health Research Board, Ireland 2013
Awards
Prof DF Murrell
•
Women’s Dermatologic Society, Mentor of the Year
Award, 2013 (Presented at the American Academy of
Dermatology, Miami, USA).
•
International League of Dermatologic Sciences
– Certificate of Appreciation for contributions
to International Dermatology education and
volunteerism.
13
Mae Ramirez
•
Women’s Dermatologic Society and AAD International
Travel Grant, 2012 to present our research at the
AAD, Miami 2013.
•
International Society of Dermatology Mentorship
Grant to spend 3 months with Dr Antonella Tosti at
the University of Miami, Florida, 2013.
Deshan Sebaratnam
•
Medical Dermatology Society Mentorship Grant
to validate our ABQOL measure in the USA at the
University of Pennsylvania with collaborator Dr Victoria
Werth.
•
Brenan Prize, Australasian Society for
Dermatopathology, for a project on BRAF mutations
in diffuse melanosis.
Clement Loh
•
Japanese Society for Investigative Dermatology
award to present our research on the validation of
a new score for EB at the International Investigative
Dermatology meeting in Edinburgh, May 2013.
•
Dean’s List Award for Research for his project on
development and validation of the EBDASI 2013.
14
>
Emergency Department,
St George Hospital
Head of Department
Trevor Chan MB ChB, Dip Paeds, FACEM
Research Staff
Stephen Asha, BSc, MBBS, FACEM, MMed(Clin Epi
Director of Emergency medicine Research, Emergency
Department, St George Hospital
Senior Lecturer (Conjoint), UNSW
Alana Clements, CNC
Allan Ajami NUM
Joanne Plowes CNS
Jacqui Fong NP
Kate Jarrett CNE
Alison Berry CNS
Bernadine Romero CNC
Margaret Fry CNC
Liz Walter CNS
Lauren Neuhaus NE
Megan Foreshew A/NUM
George Bayeh CNS
Leanne Horvat SESLHD Emergency Stream Manager
Junior Medical
Andrew Cooke MBBS; DCH; LLB; LLM
Rizwan Qureshi MBBS, MRCS Ed
Daniel Honneyman, MbChB
Richard Pryor, MD, ABEM
Research Projects in Progress
A Randomised Controlled Trial of Conservative versus
Interventional Treatment of Primary Spontaneous
Pneumothorax. Australian New Zealand Clinical
Trials Registry (ANZCTR), registration number
ACTRN12611000184976. Multicentre trial, Principal
Investigator: Dr Stephen Asha.
T3 Trial: Triage, Treatment and Transfer of Patients with
stroke in Emergency Departments. Nursing Research
Institute, Australian Catholic University. Multicentre trial,
Principal Investigator: Dr Stephen Asha.
Asia, Australia and New Zealand dyspnoea in the
Emergency Department Study. Co-ordinating investigator:
Anne-Maree Kelly, Western Health, Victoria. Multicentre
trial, Principal Investigator: Dr Stephen Asha.
Three month outcome of patients with suspected acute
coronary syndrome using point of care troponin testing
compared with laboratory based troponin testing: a
randomised trial. Asha SE, Cooke A, Walter E, Weaver J.
Benztropine for the relief of acute non-traumatic neck pain
– a randomised trial. Asha S, Kerr A, Jones K, McAlpine A.
Sensitivity and specificity of CT scanning for determining
the number of internally concealed packages in ‘bodypackers’. Asha SE, Higham M, Child P.
Accuracy of emergency physicians and trainees at
identifying internally concealed drugs on CT: do ‘lung
windows’ improve accuracy. Asha SE, Cooke A.
Does the implementation of a Chest Injury Protocol
(ChIP) for patients with blunt thoracic trauma reduce
complications and improve outcome? Curtis K, Asha SE,
Unsworth A, Langcake M.
Diagnostic utility of retinal vein pulsation on
ophthalmoscopy for predicting serious intra-cranial
pathology. Asha SE.
Factors associated with in-hospital death among elderly
patients sustaining a traumatic subdural haemorrhage.
Asha SE, Keady J, Curtis K, Kohan, S.
The effect of a nurse team leader on communication and
leadership in major trauma resuscitations. Clements, A,
Curtis K, Horvat L, Shaban R.
Pre-Post test comparison of the impact of sepsis
guidelines in ‘time to antibiotics’ in one emergency
department” Romero B, Horvat L and Fry M
Assessment and management of the cognitively impaired
older person presenting to emergency departments with
musculoskeletal conditions and injuries. Fry M, Arendts G,
Chenoweth L, Macgregor C, Dee K, Vardell W Romero B.
Exploration of the insertion and use of peripheral IV
cannulas in one emergency department. Romero B, Berry
A and Fry M.
Original Peer-Reviewed Publications
2012
Asha SE, Curtis K, Grant N, Taylor C, Lo S, Compagnoni
K. Comparison of radiation exposure of trauma patients
15
from diagnostic radiology procedures before and after the
introduction of a ‘panscan’ protocol. Emergency Medicine
Australasia 2012; 24: 43-51. (Editorial regarding this article
published in same issue: Stengel, D. Rebalancing the
major trauma computed tomography pan-scan between
panacea and pandora’s box. Emergency Medicine
Australasia 2012;24: 1-3)
Jamali S, Asha SE. Reproducibility of the seated reduction
technique for anterior shoulder dislocation when
performed by doctors with minimal experience in the
technique. Emergency Medicine: open access. 2012;
2:109 doi:10.4172/2165-7548.1000109
Qureshi R, Asha SE, Zahra M, Howell S. Factors associated
with failure to follow up with a general practitioner after
discharge from the emergency department. Emergency
Medicine Australasia. 2012; 24: 604-609.
of motion of the cervical spine using a tape measure.
Journal of Manipulative and Physiological Therapeutics.
2013; 36(8): 538-545.
Asha SE, Ajami A. Improvement in emergency department
length of stay using an early senior medical assessment
and streaming model of care: A cohort study. Emergency
Medicine Australasia. Published online first 2013 doi:
10.1111/1742-6723.12128
Arora M, Asha S, Chinnappa J, Diwan AD. Burnout in
emergency Physicians – a review. Emergency Medicine
Australasia. 2013; 25(6): 491-5.
Fry M, Horvat L, Roche M, Fong J, Plowes J (2013) A
four month prospective descriptive exploratory study
of patients receiving antibiotics in one Emergency
Department. International Emergency Nursing 21:163-167.
Clements A, Curtis K (2012) What is the impact of nursing
roles in hospital patient resuscitation? Australasian
Emergency Nursing Journal 15:108-115.
Fry M, MacGregor C, Ruperto K, Jarrett K, Wheeler J,
Fong J, Fetchet W (2013) Nursing praxis, compassionate
caring and interpersonal relations: An observational study.
Australasian Emergency Nursing Journal 16:37-44.
Curtis K, Caldwell E, Delprado A, Munroe B (2012)
Traumatic injury in Australia and New Zealand. Australasian
Emergency Nursing Journal 15:45-54.
Presentations at Scientific Meetings and
Conferences
Fry M, Horvat L, Roche M, Fong J, Plowes J (2012) The
prevalence and triage characteristics of patients presenting
with infection to one tertiary referral hospital. Australasian
Emergency Nursing Journal 15:127-132.
Fry M, Ruperto K, Jarrett K, Wheeler J, Fong J, Fetchet
W (2012) Managing the wait: Clinical initiative nurses’
perceptions of an extended practice role. Australasian
Emergency Nursing Journal 15:202-210.
2013
Asha SE, Curtis K, Taylor C, Kwok A. Patient controlled
analgesia compared to interval analgesic dosing for
reducing complications in blunt thoracic trauma: a
retrospective cohort study. Emergency Medicine Journal.
2013; 30: 1024-8.
Nichols M, Acker J, Bendall J, Asha SE. Evaluating the
incidence of unrecognised oesophageal intubation by
paramedics. Journal of Paramedic Practice. 2013; 5(4):
212-18.
Asha SE, Chan ACF, Walter E, Kelly PJ, Morton RL,
Ajami A, Wilson RD, Honneyman D. Impact from point
of care devices on emergency department patient
processing times compared with central laboratory
testing of blood samples: a randomised controlled trial
and cost-effectiveness analysis. Emergency Medicine
Journal. Published online first: 7 June 2013 doi:10.1136/
emermed-2013-202632.
Asha SE, Pryor R. Validation of a method to assess range
16
2012 – National
Qureshi R, Asha SE, Zahra M, Howell S.. Factors associated
with failure to follow up with a general practitioner after
discharge from the emergency department. Evidence
review in Emergency Medicine, November 2012, Terrigal,
NSW.
Nichols M, Acker J, Bendall J, Asha SE. Incidence
of unrecognised oesophageal intubation in patients
intubated by paramedics and transported to an Australian
metropolitan tertiary hospital. Paramedics Australasia
Conference, Hobart, 2nd December 2012.
Ajami A (2012) The First Aid Skills Training (FAST) Project.
Multicultural health research to practice forum: St George
Hospital, NSW.
Ajami A, Chan DT (2012) Medical Assessment and
Decision Making in Emergency (MADMEN) Project.
Australasian Redesigning Healthcare Summit, Brisbane.
Curtis K, Clements A, Curtis K, Holzhauser K, Horvat L
(2012) The impact of a senior nurse as nurse team leader
on communication and perceptions of leadership in major
trauma resuscitations. Trauma 2012 Conference: Perth.
Curtis K, Clements A, Holzhauser K, Horvat L (2012)
The impact of a senior nurse as nurse team leader on
communication and perceptions of leadership in major
trauma resuscitations. 10th International Conference for
Emergency Nursing: Hobart.
Horvat L, Fry M, Plowes J, Fong J (2012) To explore the
nursing assessment and initial management of septic
patients in the Emergency Department. Annual Critical
Care Conference Hunter Valley, NSW.
Romero B (2012) The emergency flow Coordinator
International Conference of Emergency Nursing: Hobart.
Romero B (2012) To identify delay reasons for ED patients
at 4 and 8 hours allowing the early identification and
escalation of delays in order to facilitate patient flow within
ED. Annual Critical Care Conference Hunter Valley, NSW
Romero B, Ajami A, Bayeh G, Neuhaus L, Foreshew M,
Cosgrove J (2012) To identify delay reasons for Ed patients
at 4 and 8 hours allowing the early identification and
escalation of delays in order to facilitate patient flow within
ED. Annual Critical Care Conference: Hunter Valley, NSW.
2013 – International Reproducibility of the seated reduction technique for
anterior shoulder dislocation when performed by doctors
with minimal experience in the technique. Presented as
an abstract in the scientific sessions of the International
Conference on Nursing & Emergency Medicine
(Nursing-2013), Las Vegas, USA, December, 2013.
2013 - National
Asha SE, Pryor R. Validation of a method to assess range
of motion of the cervical spine using a tape measure.
Evidence review in Emergency Medicine, March 2013,
Terrigal, NSW.
Chinnappa J, Arora M, Asha S, Diwan AD. Career
satisfaction among Australian emergency medicine staff:
a two centre cross sectional study (poster). Australasian
College for Emergency Medicine ACEM annual scientific
meeting, Adelaide, November 2013.
Arora M, Asha S, Diwan AD. Over half of emergency
medicine staff are burned out: Results from a two-center
cross-sectional study (poster) ACEM annual scientific
meeting, Adelaide, November 2013.
Walter L (2013) Impact from point of care devices
on emergency department patient processing times
compared with central laboratory testing of blood
samples: a randomised controlled trial and costeffectiveness analysis. International Conference of
Emergency Nursing: Melbourne.
17
>
Emergency Department,
Sutherland Hospital
Head of Department
Research Projects in Progress
January 2012- November 2013
Dr David Mah, FACEM, DHA, Conjoint Lecturer UNSW.
November/December 2013
Dr Enasio Morris FACEM (Locum Director).
Professional Development Process Pilot Study. G.Watkins
(principal investigator TSH), A. Moore, I. Ozelin.
Staff Specialists
Dr Andrea Bell, FACEM DCH
Dr Murali Krishnaraj FACEM
Dr Jeffrey Lui, FACEM
Dr David Mah FACEM, DHA, Lect (conjoint) UNSW
Dr Allison Moore FACEM
Associate Prof. John Raftos, FACEM, Snr Lect (conjoint)
UNSW
Dr Katerina Tsacalos FACEM
Dr Gina Watkins BSc(Hons), DRCOG, MRCGP, FACEM,
Lect (conjoint) UNSW
Dr Luis Winoto FACEM
Dr Peter Wyllie FACEM
A Randomised Controlled Trial of Conservative versus
Interventional Treatment of Primary Spontaneous
Pneumothorax. Australian New Zealand Clinical Trials
Registry (ANZCTR), A. Moore (principal investigator TSH).
Benztropine for the relief of acute non-traumatic neck pain
randomised trial. Asha S, Kerr A, Jones K, McAlpine A
(principal investigator TSH).
Presentations at Scientific Meetings and
Conferences
2012 National
Impact of Emergency Department Transfer Form
Mah, D. International Conference on Emergency Medicine,
Dublin June.
Visiting Medical
2013 - International
Dr Javad Najafi FACEM
Dr James Parks FACEM
G Watkins, Emergency Medicine Training in Australasia:
Nepal Emergency Medicine Seminar, Kathmandu, April.
Nursing
G Watkins, Acute Nerve Injury Pain Management:
4TH International Congress on Neuropathic Pain, Toronto
May.
Ann McAlpine, Nurse Practitioner
2013 - National
G Watkins, Emergency Department Management of Acute
Nerve Injury Pain: A review. Australasian College for
Emergency Medicine (ACEM) Annual Scientific Meeting,
Adelaide, November.
A Moore, Emergency Department Morbidity Audit, ACEM
Annual Scientific
18
>
Department of Endocrinology
Head of Department
Associate Professor Anthony O’Sullivan MBBS, FRACP,
MD, MHPEd
Senior Medical
Staff Specialists Associate Professor Terrance Diamond MB, BCh, MRCP,
FRACP
Dr Peter Rohl MBBS, FRACP
Dr Ganesh Chockalingham MBBS, FRACP, FRACGP
Dr Majgorzata Brzozowska MD, FRACP
Visiting Medical Dr Mary Freeman MBBS, FRACP Junior Medical
Advanced trainees
Dr Bobby Chan 2013
Dr Aimee Hayes 2012
Senior Researcher
Terry Golombick PhD Dipl Nutr
Research Grants
St George Hospital: Multicultural Health Service Cultural
Diversity Health Enhancement Grants Program. Craig
D, Fernandez R (2013) Clinical Management of Chinese
speaking women with Gestational Diabetes Mellitus
speaking women with Gestational Diabetes. 2012- 2013.
$6,800.
Research Projects in Progress
Changes in body composition and energy metabolism
during pregnancy: predictive of preeclampsia and
gestational diabetes mellitus? Principal investigators, A/
Prof Anthony J O’Sullivan, Odetta Davison.
Original Peer-Reviewed Publications
M M Brzozowska, P Davoren, “Does critical illness cause
reversible Cushing’s like syndrome? A case study of
two case reports and review of the literature”Journal of
Diabetes and Endocrinology Vol. 3(2), pp. 22-24, March
2012.
O’Sullivan AJ, Howe A, Miles S, Harris P, Hughes CS,
Jones P, Scicluna H, Leinster S. Does a summative portfolio
foster the development of capabilities such as reflective
practice and understanding ethics? An evaluation from two
medical schools. Medical Teacher 2012; 34: e21-e28.
Imison M, Harris P, Hewson L, Jones P, McNeil PH, Moore
K, O’Sullivan AJ, Velan G, Hughes C. A Bank of Stories:
Piloting Low-Fidelity, Student-Generated Virtual Patient
Cases in Undergraduate Medical Education. Focus on
Health Professional Education 2012; 13: 22-31.
Scicluna H, Grimm MC, O’Sullivan AJ, Pilotto L, Jones
P, McNeil HP. Clinical capabilities of graduates of an
outcomes-based integrated medical program. BMC
Medical Education 2012; 12: 23-30.
Morris J, O’Sullivan AJ. Body fat increases throughout
pregnancy despite no significant changes in 24-hour
energy expenditure and caloric intake. Obesity Research
and Clinical Practice 2012; supp 1: 59-60.
Golombick T, Diamond T, Manoharan A and Ramakrishna
R. Response to Vermorken et al – curcumin and free
light chains. American J Hematology 2012;87:E80-E81.
DOI:10.1002/ajh.23294 .
Golombick T, Diamond T, Manoharan A and Ramakrishna
R. Monoclonal Gammopathy of Undetermined
Significance (MGUS), Smoldering Multiple Myeloma (SMM)
and Curcumin: A Randomised, Double-blind PlaceboControlled Cross-over 4g study and an Open-label 8g
Extension Study. American J Hematology. 2012;87:455460.
MM Brzozowska, A Sainsbury, J Eisman, P Baldock, J
Center. Bariatric surgery, bone loss, obesity and possible
mechanisms. Obesity Reviews 2013 14(1):52-67- selected
as “Hot topic publication” by ESA society.
Olupeliyawa Asela M, Balasooriya CD, Hughes C,
O’Sullivan AJ. Commencing clinical practice as a medical
graduate: what collaborative behaviors and competencies
are critical? Focus on Health Professional Education 2013;
14: 57-70.
Chan B, O’Sullivan AJ. Investigating disorders of
hyponatraemia. Endocrinology Today 2013; 2: 38-40.
Mavros Y, Kay S, Anderberg KA, Baker MK, Wang Y, Zhao
R, Meiklejohn J, Climstein M, O’Sullivan A, De Vos N,
19
Baune B, Blair SN, Simar D, Rooney K, Singh N, Fiatorone
Singh MA. Changes in insulin resistance and HbA1c are
related to exercise-mediated changes in body composition
in older adults with Type 2 Diabetes: Interim outcomes
from the GREAT2DO trial. Diabetes Care 2013, published
online March 8.
Tang A, O’Sullivan AJ, Diamond D, Gerard A, Campbell
P. Psychiatric symptoms as a clinical presentation of
Cushing’s syndrome. Annals of General Psychiatry 2013;
12: 23.
Wong R, Golombick T, Diamond T, Manoharan A and
Ramakrishna R. Curcumin enhances the cytotoxic and
chemo-sensitising effects of lenalidomide in human
multiple myeloma cells. J Hematological Malignancies,
2013,Vol 3, no 2,1-7.
Golombick T, Diamond T, Manoharan A and Ramakrishna
R. Long term use of curcumin in two smoldering multiple
myeloma patients. J Hematological Malignancies, 2013,
Vol 3, no 1, 18-23.
Diamond T, Golombick T and Wong Y. The effect of oral
cholecalciferol 2000 IU versus 5000 IU on serum vitamin
D, PTH, bone and muscle strength in patients with vitamin
D deficiency. Osteoporosis International (2013)24:11011105.
Denham JW, Nowitz, M, Joseph D, Duchesne G, Spry
NA, Lamb DSs, Matthews J, Turner S, Atkinson C, Tai KH,
Gogna NK, Kenny L, Diamond T, Smart R, Rowan D,
Moscato P, Woodfield R, Lynch K, Dalahunt, Murray J,
D’Este C, McElduff P, Steigler, A, Kautto A, and Ball J.
Impact of androgen suppression and zoledronic acid on
bone mineral density and fractures in the Trans-Tasman
Radiation Oncology Group (TROG) 03.04 Randomised
Androgen Deprivation and Radiotherapy (RADAR)
randomized controlled trial for locally advanced prostate
cancer. BJU International October 15 2013 Doi: 10.111/
bju.12497.
Bokhari AR, Davies MA. Diamond T. Endoscopic
transsphenoidal pituitary surgery: a single surgeon
experience and the learning curve. British J of
Neurosurgery. 2013 February 27(1) 44-49.
Presentations at Scientific Meetings and
Conferences
International
Brzozowska, M. Differential bone loss following gastric
surgery at 12 months-late breaking abstract with oral
presentation at the 34th Annual Meeting of the American
Society for Bone and Mineral Research (ASBMR),
Minneapolis, Minnesota, October 2012.
Mavros Y, Rooney K, Kay S, Simar D, Anderberg K, Baker
20
M,Wang Y, Zhao R, Climstein M, O’Sullivan AJ, Baune
B, Blair S, Fiatarone-Singh M. Relative muscle mass is
inversely associated with inflammation in older adults
with Type 2 diabetes. 3rd World Congress on Exercise is
Medicine, San Francisco, CA 2012. No 1103.
Mavros Y, Rooney K, Kay S, Simar D, Anderberg K, Baker
M,Wang Y, Zhao R, Climstein M, O’Sullivan AJ, Baune
B, Blair S, Singh N, Fiatarone-Singh M. Relative muscle
mass is inversely associated with insulin resistance in older
adults with Type 2 diabetes. 19th European Congress of
Obesity, Lyon, France 2012. No. 851.
Morris J, O’Sullivan AJ. Body fat increases throughout
pregnancy despite no significant changes in 24-hour
energy expenditure and caloric intake. Australian & New
Zealand Obesity Society Annual Scientific Meeting,
Auckland, New Zealand 2012.
Golombick T, Diamond T, Manoharan A and Ramakrishna
R. Multiple Myeloma Precursor Disease and Curcumin.
14th International Myeloma Workshop, April 3-7, 2013,
Kyoto, Japan.
Golombick T, Wong R, Diamond T, Manoharan A and
Ramakrishna R. Curcumin Enhances the Cytotoxic and
Chemosensitising Effects of Lenalidomide in Human
Multiple Myeloma Cells. Fourteenth International Myeloma
Workshop, April 3-7, 2013, Kyoto, Japan.
Brzozowska, M. Bone loss following bariatric surgery:
Comparison of different modalities, featured poster
presentation, The Endocrine Society 95th Annual Meeting,
San Francisco 2013 (awarded Postgraduate Research
Support Scheme (PRSS) Grant UNSW).
National
Malgorzata Brzozowska “Bone loss following bariatric
surgery: Comparison of different modalities”-Endocrine
Society of Australia (ESA) Conference Sydney, Darling
Harbour, April 2013 (ESA Novartis Award Finalist).
Jones P, O’Sullivan AJ, Velan G, Thompson R, Balasooriya
C, Kumar R, Harris P. A programmatic approach to
standards-based assessment in medicine. Learning and
Teaching Forum: Assurance of Learning, UNSW, Sydney,
2012.
Hayes A, Iskander A, O’Sullivan AJ, Diamond D. Will new
GDM diagnostic criteria impact on resource allocation as
defined by GDM prevalence and proportion of women
requiring insulin therapy? Australian Diabetes in Pregnancy
Society Annual Scientific Meeting, Gold Coast, 2012.
Morris J, O’Sullivan AJ. Accumulation of body fat during
pregnancy occurs despite no significant changes in energy
expenditure and caloric intake. Australian Diabetes in
Pregnancy Society Annual Scientific Meeting, Gold Coast,
2012.
White C, Chen K, Lip C, Lee J, XuGuang H, Hong A,
Bleicher K, Lowe S, O’Sullivan A.J. Vitamin D insufficiency
is prevalent but does not influence glycaemia in
pregnancy. Annual Scientific Meeting of the Endocrine
Society of Australia, Gold Coast 2012.
Since commencement of the Group 244 participants have
attended groups. The majority of referrals have been from
The Diabetes Education Centre.
Community Engagement
Introduction of a weekly block booking Chinese Interpreter
supported Chinese speaking Gestational Diabetes review
clinic. This clinic has improved access for these women
and provided opportunities for regular review and
psychosocial support.
The Diabetes Group Report
The Diabetes Education Centre continues to provide a
service to the St George Division of General Practice for a
group education program.
The target group suffers from insulin resistance, impaired
fasting glucose, Type 2 patients. Referral sources included:
•
Diabetes Education Centre,
•
Diabetes Clinic,
•
Nutrition department,
•
Other Allied Health
•
General Practitioners.
Chinese Speaking Gestational Diabetes Mellitus Clinic
Awards
Dr Malgorzata Brzozowska
NHMRC (National Health and Medical Research Council)
scholarship for the PhD project, UNSW: “The association
between neuropeptides, gut hormones, skeletal and
metabolic health”. 2009-2013
Exclusions: Non English speaking and children.
Venue: Division of General Practice
The program consisted:
Session 1 Understanding your condition
Session 2 Nutrition
Session 3 Podiatry
Session 4 Ophthalmology
Session 5 Nutrition
Session 6 Physical Activity
Each session except session 1 contain physical activity
component
The session given by the educator includes the following
topics:
1. Healthy eating (brief as covered by dietitian)
2.
Being Active (brief as covered by exercise physiologist)
3.Monitoring
4.
Taking Medication
5.
Problem Solving
6.
Healthy Coping
7.
Reducing risks
21
>
Department of Gastroenterology
and Hepatology
Head of Department
A/Prof Amany Zekry, MBBS, PhD, FRACP, Associate
Professor of Medicine
Senior Medical
Prof Ian Cook, MBBS, FRACP, MD, Professor of Medicine
(Conjoint)
Prof Michael Grimm, MBBS (Hons), PhD, FRACP, Clinical
Associate Dean, St George and Sutherland Clinical School.
A/Prof Philip Craig, MBBch, PhD, FRACP, Associate
Professor of Medicine (Conjoint)
Dr John Freiman, MBBch, PhD, FRACP
Dr Lennart Choo, MBBS, FRACP
Dr Gokulan Paven, MBBS, FRACP, Snr Lecturer (Conjoint)
Junior Medical
Dr Peter Wu, MBBS
Dr Peter Lim, MBBS
Dr Vipul Aggarwal, MBBS
Research Staff
Dr Michal Szczesniak, BBiomedSc (Hons), PhD, Post-Doc
Research Fellow, St George and Sutherland Clinical School
Ms Teng Zhang, MBiomedEng, PhD student, St George
and Sutherland Clinical School
Dr Greta Lee, MB BS, MMed (Clin. Epi.), FRACP, PhD
student, St George and Sutherland Clinical School
Ms Annie Luo, BSc (Hons), PhD student, St George and
Sutherland Clinical School
Ms Linda El-Bayeh, BSc (Hons), Research assistant, St
George and Sutherland Clinical School
Ms Lisa Dowdell Clinical Nurse Consultant – Community
Liver Disease
Ms Amy Ko - Clinical Trials Coordinator
Research Grants
NHMRC Project Grant Predicting dysphagia-related
complications and improving outcomes in patients treated
with head and neck radiotherapy, I Cook, M Szczesniak, J
Maclean, P Graham, T Omari $301,624 0; (2013 - 2015).
NHMRC Project Grant, Development of diagnostic tools to
characterise predictors of therapeutic outcome in severe
constipationPG Dinning, I Cook, J Arkwright, M Scott, DZ
Lubowski, $418,500; (2010 – 2012).
UNSW MREII scheme Veneflux system, Multiple platelet
22
function analyzer, Fluoroskan Ascent FL fluorescent plate
reader, Leica inverted fluorescence microscope, Grimm
MC, O’Sullivan A, Chong B, Krilis SA, Morris DL $240,722
(2012).
NHMRC Equipment grant + UNSW MREII scheme
Tuttnauer Autoclave, Step One Plus 96 well Quantitative
PCR Machine, AKTA Avant 150 FPLC System, Direct Detect
Spectrometer Grimm MC, Chong B, Krilis S, Morris DL, Li
Y.$353,190 , (2013).
UNSW MREII scheme, Establishment of a biostatistical
unit for UNSW Medicine, Hayen A, McIntyre R, Harris M,
Lassere M, Grimm MC, Zwar N, Worth H. $387,905, (2013).
UNSW MREII scheme, Lloyd AR, Grimm MC and 15 other
investigators Bioplex Magpix with wash station, $71,138
(2013).
Research Projects in Progress
Predicting dysphagia-related complications and improving
outcomes in patients treated with head and neck
radiotherapy. Principal investigators: I Cook, M Szczesniak,
J Maclean, P Graham, T Omari.
Prospective, randomized controlled trial of cricopharyngeal
dilatation in post-laryngectomy dysphagia. Principal
investigators: P Wu, M Szczesniak, J Maclean, I Cook.
Influence of altered pharyngo-esophageal biomechanical
parameters on swallowing and speech function in
laryngectomees, Principal investigators: T Zhang, M
Szczesniak, J Maclean, P Bertrand, I Cook.
The role of Campylobacter concisus in the pathogenesis of
IBD, Principal investigators: Zhang L, Grimm MC, Riordan S.
The appendix, appendicitis, and the immunology of
protection against IBD, Principal investigators: Luo AS,
Philips P, Grimm MC.
The role of the chemokine-chemokine receptor pair,
CCL20-CCR6, in intestinal immunity and inflammation,
Principal investigators: Eri R, Lyons AB, Korner H, Grimm
MC.
The role of balloon-assisted cholangioscopy, Principal
investigators: Lim P, Craig P.
Capsule endoscopy study of small bowel Crohn’s disease
patients in clinical remission, Principal investigators:
Aggarwal V, Day AS, Connor SJ, Leach ST, Brown, GJ.
Singh R, Friedman A, Grimm MC, Craig, PI.
Gilead 121. Phase 2 Randomized, Open-Label, Exploratory
Trial of GS 5885, GS 9451 with Peginterferon Alfa 2a
(PEG) and Ribavirin (RBV) in Treatment-Naïve subjects with
chronic Genotype 1 Hepatitis C virus Infection and IL28B
CC Genotype Principal investigator: A/Prof. Amany Zekry.
interferon-α and ribavirin in Treatment-naïve patients with
Chronic Genotype 1b HCV Infection. Principal investigator:
A/Prof Amany Zekry.
A Multi centred 3 year follow up study to assess the
durability of sustained virologic response to Alisporivir
treated chronic HCV patients. Principal investigator: A/Prof
Amany Zekry.
Gilead – FISSION. Phase 3, Multicenter, Randomized,
Active-controlled Study to investigate the safety and
efficacy of PSI-7977 and Ribavirin for 12 weeks Compared
to Pegylated Interferon and Ribavirin for 24 weeks in
treatment-naïve patients with chronic genotype 2 or 3 HCV
infection, Principal investigator: A/Prof Amany Zekry.
A Multicenter, Randomized, Double-blind, Phase 3 Study
of Ramucirumab (IMC-1121B) Drug Product and Best
Supportive Care (BSC) versus Placebo and BSC as Secondline Treatment in Patients With Hepatocellular Carcinoma
F ollowing First-line Therapy. Principal investigator: A/Prof
Amany Zekry.
Gilead 109. Open label study of GS7977 and Ribavirin
for 12 weeks for subjects with chronic HCV infection who
participated in prior studies evaluating GS7977, Principal
investigator: A/Prof Amany Zekry.
Original Peer-Reviewed Publications
Phase 3, Open Label study with Asunaprevir and
Daclastasvir (DUAL) for Null/partial responders to Peg
Alfa 2a and Ribavirin, Intollerant/Ineligible naïve to P/R
subjects, and treatment naïve subjects with chronic HCV
genotype 1b, Principal investigator: A/Prof Amany Zekry.
BMS-A1444-026. An open-label re-treatment study with
Peg-Interferon Alfa-2, Ribavirin and BMS-7090052 with or
without BMS-650032 for subjects with Chronic Hepatitis C,
Principal investigator: A/Prof Amany Zekry.
Novartis DEB025A2210. A phase II clinical trial to evaluate
the efficacy and safety. A multicentre, randomized, doubleblind, placebo-controlled, parallel-group phase II study on
the efficacy and safety of DEB025/Alisporivir combined
with peg-IFN alfa-2a and ribavirin in chronic hepatitis C
genotype 1 patients who are previous peg-IFN alfa-2 plus
ribavirin treatment-non-responders, Principal investigator:
A/Prof Amany Zekry.
Novartis DEB025A2301. A randomized, double-blind,
placebo-controlled trial of the efficacy and safety of
DEB025/Alisporivir in combination with standard of care in
hepatitis C genotype 1 treatment naïve patients. Principal
investigator: A/Prof Amany Zekry.
A Phase III, Randomised, open label, parallel group,
Active-controlled study of an interferon-free regimen of
BI 207127 in combination with Faldaprevir and Ribavirin
compared to Telaprevir in combination with pegylated
2012
Dinning PG, Hunt L, Arkwright JW, Patton V, Szczesniak
MM, Wiklendt L, Davidson JB, Lubowski DZ, Cook IJ.
Pancolonic motor response to sub-and suprasensory sacral
nerve stimulation in patients with slow transit constipation.
Br J Surg. 2012; 99(7):1002-10.
P.I. Craig, The role of endoscopic stenting for biliary
strictures in chronic pancreatitis. Dig Endosc. 2012;
24(Suppl 1):38-42.
McNeil HP, Scicluna H, Boyle P, Grimm MC, Gibson KA,
Jones P. Successful development of generic capabilities
in an undergraduate medical education program. Higher
Education Research and Development 2012; 31:525-539.
Ismail Y, Mahendran V, Octavia S, Day AS, Riordan
SM, Grimm MC, Lan R, Lemberg D, Tran TAT, Zhang L.
Investigation of the enteric pathogenic potential of oral
Campylobacter concisus strains isolated from patients with
inflammatory bowel disease. PLoS ONE 2012; 7(5):e38217.
Scicluna H, Grimm MC, O’Sullivan AJ, Pilotto L, Jones
P, McNeil HP, Clinical capabilities of graduates of an
outcomes-based integrated medical program. BMC
Medical Education 2012; 12:23-28.
Choo L, Conway J, Mishra G. The role of endoscopic
ultrasound in biliary obstruction. Current Gastroenterology
Reports 2012; 14(6): 520-7.
Keoshkerian E, Helbig K, Beard M, Zaunders J, Seddiki N,
23
Kelleher A, Hampartzoumian T, Zekry A, Lloyd AR. A novel
assay for detection of hepatitis c virus-specific effector
cd4(+) t cells via co-expression of cd25 and cd134. Journal
of immunological Methods 2012;375:148-158.
Guirgis M, Yan K, Bu YM, Zekry A. General practitioners’
knowledge and management of viral hepatitis in the
migrant population. Internal Medicine Journal 2012;
42:497-504.
Guirgis M, Nusair F, Bu YM, Yan K, Zekry AT. Barriers faced
by migrants in accessing healthcare for viral hepatitis
infection. Internal Medicine Journal 2012; 42:491-496.
2013
Szczesniak MM, Fuentealba SE, and Cook IJ. Acid
Sensitization of Esophageal Mucosal Afferents:
Implication for Symptom Perception in Patients across the
Gastroesophageal Reflux Disease Spectrum. Clin J Pain
2013; 29(1):70-7.
Elliott TR, Wu PI, Fuentealba S, Szczesniak M, de Carle
DJ, Cook IJ. Long-term outcome following pneumatic
dilatation as initial therapy for idiopathic achalasia: an
18-year single-centre experience. Aliment Pharmacol Ther.
2013; 37(12):1210-9.
Mahendran V, TanYS, Riordan SM, Grimm MC, Day AS,
Lemberg DA, Octavia S, Lan R, Zhang L. The prevalence
and polymorphisms of zonula occluden toxin gene in
multiple Campylobacter concisus strains isolated from
saliva of patients with inflammatory bowel disease and
controls. PLoS ONE 2013; 8(9):e75525.
Zbaras B, Sam LN, Grimm MC. Thrombotic
thrombocytopaenic purpura associated with adalimumab
(Humira) treatment in Crohn disease. Internal Medicine
Journal 2013; 43(2): 216-217.
Other Published Material
Cook IJ. Investigating the patient with difficulty
swallowing: The importance of a thorough history.
Medicine Today 2012;13(9):48-53.
Cook IJ. Zenker’s Diverticulum. In: Shaker R, Postma G,
Belafsky P, Easterling C, Eds Principles of Deglutition: A
Multidisciplinary Text for Swallowing and its Disorders.
New York: Springer: 2013. (ISBN 978-1-4614-3794-9).
Cook IJ. Globus Pharyngeus In: Shaker R, Postma G,
Belafsky P, Easterling C, Eds Principles of Deglutition: A
Multidisciplinary Text for Swallowing and its Disorders.
New York: Springer: 2013. (ISBN 978-1-4614-3794-9).
Kumbhari V, Behary J, Szczesniak M, Zhang T, Cook IJ.
Efficacy and safety of pneumatic dilatation for achalasia in
the treatment of post-myotomy symptom relapse. Am J
Gastroenterol. 2013; 108(7):1076-81.
Presentations at Scientific Meetings and
Conferences
Szczesniak MM, Fuentealba SE, Zhang T, Cook IJ.,
Modulation of esophageal afferent pathways by 5-HT3
receptor inhibition. Neurogastroenterol Motil. 2013;
25(5):383-8, e293.
I.J. Cook, Newer understanding of UES function
with high resolution manometry. Joint International
Neurogastroenterology and Motility Conference, Bologna,
Italy, Sept 2012.
Ismail Y, Lee H, Riordan SM, Grimm MC, Zhang, The
effects of oral and enteric Campylobacter concisus strains
on expression of TLR4, MD-2, TLR-2, TLR5 and COX-2 in
HT-29 cells. PLoS ONE 2013; 8(2):e56888.
V. Kumbhari, J. Behary, M.M. Szczesniak, M. Naidoo,
I.J. Cook, Efficacy and Safety of Pneumatic Dilatation
in Patients With Achalasia Who Relapse Post Heller
Myotomy. Gastroenterology, Volume 142, Issue 5,
Supplement 1, May 2012, Page S-282.
Walsh AJ, Weltman M, Burger D, Vivekanandarajah S,
Connor S, Howlett M, Radford-Smith G, Selby W, Veillard
AS, Grimm MC, Travis SPL, Lawrance I. Implementing
guidelines on the prevention of opportunistic infections
in inflammatory bowel disease. Journal of Crohn’s and
Colitis. 2013; 7:e449–e456.
Handford C, Burton A, Lemon J, Grimm MC, VollmerConna U. Reading emotion in the eyes: empathy as a
function of clinical exposure. PLoS ONE 2013; 8(6):e65159.
Lee AYS, Eri R, Lyons AB, Grimm MC, Korner H.
CC chemokine ligand 20 and its cognate receptor CCR6
in mucosal T cell immunology and inflammatory bowel
disease: Odd couple or axis of evil?Frontiers in Mucosal
Immunity 2013; 4:194-200.
24
2012 - International
S. Paramsothy, J. Maclean, M. M. Szczesniak, I. J. Cook.
Cricopharyngeal Dilatation for Post Laryngectomy
Dysphagia - a Pilot Study of Efficacy and Safety.
Gastroenterology, Volume 142, Issue 5, Supplement 1,
May 2012, Page S-235.
S. Paramsothy, J. Maclean, M. M. Szczesniak, I. J. Cook.
Oesophageal Dysmotility in Laryngectomy Patients - is
There an Association? Gastroenterology, Volume 142,
Issue 5, Supplement 1, May 2012, Pages S-235-S-236.
P.I. Craig, Contrast capsule endoscopy: The Australian
experience. Capsule Endoscopy Experts Forum CEEF,
Vienna, February.
V. Aggarwal, A.S. Day, S.J. Connor, S.T. Leach, G.J.
Brown, R. Singh, A, Friedman, M.C. Grimm, P.I. Craig,
“Multicenter capsule endoscopy study of small bowel
Crohn’s disease patients in clinical remission: long-term
follow-up and correlation with faecal biomarkers and
clinical outcome.”, Oral, DDW Gastroenterology 142 (5).
Grimm M.C. The appendix in IBD: from epidemiology to
mechanism. Oral, Oxford IBD Masterclass, Oxford, UK.
2012 - National
Szczesniak M, Fuentealba SE, Cook IJ. Involvement of
5-HT3 neural pathways in oesophageal sensitivity and
acid-induced viscerosomatic sensitisation. Oral, Australian
Gastroenterology Week, Adelaide, October. Journal of
Gastroenterol Hepatol 2012:27(Suppl 4):A155 .
Lim P, Craig PI. Balloon-assissted cholangioscopy:
technique, diagnostic and therapeutic applications. Oral
(video forum), Australian Gastroenterology Week,
Adelaide, October.
Ghaly S, Craig PI. Over the scope clip to close an
entero-cutaneous fistula. Oral (video forum), Australian
Gastroenterology Week, Adelaide, October.
Lim P, Aggarwal V, Craig PI., Peroral balloon-assisted
cholangioscopy for complex biliary disease in a multiethnic cohort. Oral, Australian Gastroenterology Week,
Adelaide, October. J Gastroentrol & Heptol, 27 (supp
4):S59.
Aggarwal V, Day AS, Connor SJ, Leach ST, Brown GJ,
Singh R, Friedman A, Grimm MC, Craig, PI. Multicenter
capsule endoscopy study of small bowel Crohn’s disease
patients in clinical remission: long-term follow-up and
correlation with faecal biomarkers and clinical outcome.
Oral, Australian Gastroenterology Week, Adelaide,
October, J Gastroentrol & Heptol, 27 (supp 4):S96.
PI Craig. Inflammatory lesions , NETI National Endoscopy
Training Initiative, capsule course, Sydney; July.
PI Craig. Tumours and polyposis syndrome, NETI National
Endoscopy Training Initiative, capsule course, Sydney; July.
PI Craig. Primary sclerosing cholangitis: Endoscopic
management and cholangiocarcinoma diagnosis. ALA
Australian Liver Association Masterclass, Sydney, July.
PI Craig. New paradigms in pancreatico-biliary diseases:
case-based discussion and updates. Gut Club, Sydney;
August.
PI Craig. Australian Multicentre Balloon-assisted
Cholangioscopy Study. Oral, ANZELF Australia & New
Zealand Endoscopy Leaders Forum: Darwin; August.
PI Craig. Entero-cutaneous fistula closure with an OTSC
device. ANZELF Australia & New Zealand Endoscopy
Leaders Forum: Darwin; August.
PI Craig. Luminal stenting: Do’s and Don’ts. Australian
Gastroenterology Week, Adelaide, October.
PI Craig. Capsule endoscopy in Crohn’s: Assessing disease
remission. Australian Gastroenterology Week, Adelaide,
October.
Grimm M.C. Inflammatory cascades in IBD, Macarthur
Series in Immunology. Campbelltown, NSW.
Grimm M.C. Pregnancy and IBD. Society of Obstetric
Medicine of Australian and New Zealand Annual Scientific
Meeting Sydney, NSW.
Choo L, Mishra G, Conway J, Evans J. Prospective single
blinded study of EUS prior to ERCP for patients with a
positive intra-operative cholangiogram. Oral, Australian
Gastroenterology Week. Adelaide, October.
Choo L, Mishra G, Evans J, Conway J. Endoscopic
ultrasound training: The impact on procedure time and
complications. Poster, Australian Gastroenterology Week.
Adelaide, October.
Wu PI, Szczesniak MM, Craig PI, Choo L. Predictors
of rebleeding in high risk peptic ulcer disease in the
era of modern endoscopic therapy and high dose
intravenous proton pump inhibitors. Poster, Australian
Gastroenterology Week. Adelaide, October.
Choo L. AGEA update 2013- pancreatico-biliary.
Australian Gastroenterology Week, Adelaide,
October.
2013 - International
M.M. Szczesniak, J. Maclean, T. Zhang, P. Graham,
IJ. Cook. Prevalalence of Dysphagia as a long term
complication of head and neck radiotherapy, Oral
Presenation 3rd Congress of the European Society for
Swallowing Disorders, 2013 Malmo, Sweden.
M.M. Szczesniak, T.I. Omari, J. Maclean, R. Liu, T. Zhang,
I.J. Cook. Inter-rater reliability of automated impedancemanometry (AIM) analysis and fluoroscopy in patients with
dysphagia following head and neck radiotherapy. Oral
Presenation 3rd Congress of the European Society for
Swallowing Disorders, 2013, Malmo, Sweden.
M.M. Szczesniak, Cook I.J. Normal values for sydney
swallow questionnaire (SSQ), Poster Presentation,
3rd Congress of the European Society for Swallowing
Disorders, Malmo, Sweden, 2013.
Rebecca Burgell, Michal M. Szczesniak, Priyanka
Yerragorla, Emma V. Carrington, Sahar Mohammed,
Peter J. Lunniss, Philip G. Dinning, S. Mark Scott. Quality,
Intensity and Location of the Urge to Defaecate Differs
Between Patients With Constipation and Healthy Subjects,
DDW, Gastroenterology, Volume 144, Issue 5, Supplement
25
1, May 2013, Page S-935.
Lim P, Craig PI. The role of balloon-assisted
cholangioscopy: Diagnosis and Therapy, Oral (video
forum) Digestive Diseases Week, Orlando, FA. USA, May.
Lim P, Aggarwal V, Craig PI, The role of balloon-assisted
cholangioscopy in a multi-ethnic cohort to assess complex
biliary disease. Digestive Diseases Week, Orlando, FA.
USA, May.
National - 2013
PI Craig. Advances in the endoscopic diagnosis
of malignancies of the bile duct. Oral, Australian
Gastroenterology Week, October, Melbourne.
PI Craig. Intrahepatic biliary dysplasia complicating a
choledochal cyst: Diagnosis and management. Australian
Gastroenterology Week, October, Melbourne.
PI Craig. Defining normal and normal variants in capsule
endoscopy. NETI National Endoscopy Training Initiative,
capsule course, Sydney.
PI Craig. Direct Cholangioscopy in 2013 and Beyond.
RPAH Biliary Workshop, Sydney.
Wu PI, Szczesniak MM, Craig PI, Choo LK. Predictors of
rebleeding in high risk peptic ulcer disease in the era of
modern endoscopic therapy and high dose intravenous
proton pump inhibitors. Australian Gastroenterology
Week, October, Melbourne.
Grimm M.C. Optimising therapy in IBD. Raising
Expectations in Gastroenterology, Sydney and Newcastle.
Luo AS, Jung H-J, Philips P., Grimm M.C. The mechanisms
of regulatory T cell expansion following appendicitis
induction. Poster, Australian Gastroenterology Week,
October, Melbourne.
26
>
Infectious Disease, Immunology
and Sexual Health
Head of Department
Prof. Steven A. Krilis, MB BS PhD DSc (Hons) FRACP
FAAAA, Conjoint Professor of Medicine UNSW
Senior Medical
Dr. Pamela Konecny, MB BS MD DTM&H(Lon) FRACP
FAChSHM Conjoint Snr Lecturer in Medicine UNSW
Dr. Chris Weatherall, MB BS PhD FRACP, Conjoint Lecturer
in Medicine UNSW
Dr. Josephine Lusk, BSc MBChB FRNZCGP DRCOG
FAChSHM MPH Dip MGT, Conjoint Senior Lecturer
Medicine, UNSW, Director of Sexual Health
Dr. Damian Conway, MB BCh, MMed (HIV/STD) FAChSHM
MRCGP, Lecturer in Medicine UNSW
Dr. Catherine Pell, MBBS MM (Sex Hth) FAChSHM
Research
Sharon Robinson CNC Clinical Trials
Dr. Bill Giannakopoulos MBBS PhD FRACP – Director of
Research
Dr. Jian Chen Qi Master of Medicine , PhD, Senior
Scientist./Laboratory Manager
Miao Qi, Bachelor of Medicine in Medical Laboratory
Science, MSc (UNSW).
Peyman Mirarabshahi, PhD
Mahmood Abdelatti MSc
Visiting Fellow Dr. Peng Zhang, Bachelor of Clinical
Medicine, PhD
Visiting Fellow Dr. Siajun Zhou, Bachelor of Clinical
Medicine, MSC, PhD
Postdoctoral Fellow Dr. Gang Chen, MBBS, PhD
Research Grants
NHMRC, Tests for risk of thrombosis in patients with
certain autoimmune conditions. Principal investigators
Steven Krilis, Bill Giannakopoulos, $300,000, $190,000,
$190,000, 2012-2014.
NHMRC, Delineation of the role of RasGRP4 in mast cell
growth, differentiation and activation, using RasGRP4
deficient mice. Principal investigator Steven Krilis $204,500
yearly, 2010-2012.
UNSW Goldstar Award, The role of Mast cell specific
proteases in inflammatory bowel disease in mice and
humans. Principal investigators Steven Krilis, Michael
Grimm $40,000, 2012.
St. George & Sutherland Medical Research Foundation,
Innate Immunity in Thrombosis and Ischaemia Perfusion
Injury Principal investigators Steven Krilis, $30,000, 2013.
NSW Ministry of Health, NSW Rapid HIV Testing
Evaluation Framework, Principal Investigators: Rebecca
Guy, Garrett Prestage Damian Conway, Martin Holt,
Andrew Grulich, John Kaldor, Philip Cunningham,
$433,210 over 2 years (2013-2014).
Australian Rotary Health & The Kirby Institute HIV PhD
Scholarship, Novel approaches to HIV testing for men who
have sex with men, Investigator: Damian Conway, $72,000
over 2.5 years (January 2012-July 2014).
Research Projects in Progress
Delineation of the role of RasGRP4 in mast cell growth,
differentiation, Principal investigator: Steven Krilis.
Tests for risk of thrombosis in patients with certain
autoimmune conditions , Principal investigators Bill
Giannakopoulos, Steven Krilis.
NSW Rapid HIV Testing Evaluation Framework, Principal
Investigators: Rebecca Guy, Garrett Prestage Damian
Conway, Martin Holt, Andrew Grulich, John Kaldor, Philip
Cunningham.
Original Peer-Reviewed Publications
2012
Adachi R, Krilis SA, Nigrovic PA, Hamilton MJ, Chung
K, Thakurdas SM, Boyce JA, Anderson P, Stevens RL.
Ras guanine nucleotide releasing protein-4 (RasGRP4)
involvement in experimental arthritis and colitis. J Biol
Chem. 2012 Jun 8;287(24):20047-55.
Giannakopoulos B, Gao L, Qi M, Wong JW, Yu DM,
Vlachoyiannopoulos PG, Moutsopoulos HM, Atsumi T,
Koike T, Hogg P, Qi JC, Krilis SA. Factor XI is a substrate
for oxidoreductases: Enhanced activation of reduced FXI
and its role in antiphospholipid syndrome thrombosis. J
Autoimmun. 2012 Sep;39(3):121-9.
Giannakopoulos B, Mirarabshahi P, Krilis S. New insights
into the biology and pathobiology of Beta 2-glycoprotein
I. Curr Rheumatol Rep. 2012;13:90-5.
Mirarabshahi P, Abdelatti M, Krilis S. Post-translational
oxidative modification of B2-glycoprotein I and its role in
27
the pathophysiology of the antiphospholipid syndrome.
Autoimmun Rev. 2012;11(11):779-80.
Erkan D, Lockshin MD; APS ACTION members. (Krillis S)
APS ACTION--AntiPhospholipid Syndrome Alliance for
Clinical Trials and International Networking. Lupus. 2012
Jun;21(7):695-8.
Conway DP, Healey LM, Rauwendaal E, Templeton DJ,
Davies SC. Providing HIV negative results to low-risk
clients by telephone. Sexual Health. 2012, 9(2): 160-165.
2013
Giannakopoulos B, Krilis SA. The pathogenesis of the
antiphospholipid syndrome. N Engl J Med. 2013 Mar
14;368(11):1033-44.
Yong A, Pennings G, Wong C, Javadzadegan A, Brieger
D, Lowe H, Qi M, Behnia M, Krilis S, Kritharides L.
Intracoronary upregulation of platelet extracellular matrix
metalloproteinase inducer (CD147) in coronary disease. Int
J Cardiol. 2013 Jul 1;166(3):716-21.
Lusk MJ, Uddin RNN, Lahra MM, Garden FL, Kundu
RL, Konecny P. Pharyngeal Gonorrhoea in Women: An
Important Reservoir for Increasing Neisseria gonorrhoea
Prevalence in Urban Australian Heterosexuals?,” Journal
of Sexually Transmitted Diseases 2013: Article ID 967471
5 pages.
Wierema J, Konecny P, Links M. Implementation of risk
stratified antibiotic therapy for neutropenic fever: what
are the risks? Internal Medicine Journal 2013:43(10):
1116–1124.
Bourne C, Allen D, Brown K, Davies SC, McNulty A,
Smith DE, O’Connor CC, Couldwell D, Jackson E, Bolton
M, Rodgers C, Konecny P, Smith DJ, Parker A. What
proportion of sexually transmissible infections and HIV
are diagnosed in New South Wales’ public sexual health
services compared with other services? Sexual Health
2013; 10(3):290.
Prabhu A, Taylor P, Konecny P, Brown M. Pyelonephritis:
What are the present day causative organisms and
antibiotic susceptibilities? Nephrology 2013;18:463–467.
Xu Y, Weatherall C, Bailey M, Alcantara S, De Rose R,
Estaquier J, Wilson K, Suuzuki K, Corbeil J, Coo[per
DA, Kent SJ, Kelleher AD, Zaunders J. Simian
immunodeficiency virus infects follicular helper CD4+ Tcell
T cells in lymphoid tissues during pathogenic infection of
pigtail macaques. J Virol 2013 Apr; 87(7):3760-73.
Lusk MJ, Uddin RNN, Lahra MM, Garden FL, Kundu RL
and Konecny P. Pharyngeal Gonorrhoea in Women: An
Important Reservoir for Increasing Neisseria gonorrhoea
Prevalence in Urban Australian Heterosexuals? Journal of
Sexually Transmitted Diseases. Volume 2013;1-5.
28
Bavinton BR, Brown G, Hurley M, Bradley J, Keen P,
Conway DP, Guy R, Grulich AE, Prestage G. Which gay
men would increase their frequency of HIV testing with
home self-testing? AIDS and Behavior. 2013:1-9.
Other Published Material
2012
Conway D, Holt M, Atkinson M, Marshall L, McCloskey
J, Langdon P, Callander D, Guy R. The Western Australia
Sexual Health Service (WASHS) Project: A review of sexual
health services for gay, bisexual and other men who have
sex with men in Western Australia. Survey report July
2013. The Kirby Institute, Sydney.
Presentations at Scientific Meetings and
Conferences
2012 - International
Krillis S. Invited speaker. The role of oxidation in induction
of autoantibodies to Beta 2GPI in patients with the
Antiphospholipid syndrome. Autoimmunity Workshop.
Athens, Greece. July.
Krillis S. Invited speaker. Management of thrombosis
in the Antiphospholipid syndrome. Excellence in
Rheumatology. Madrid, Spain. 25-January.
Krillis S, Chairperson. Antiphospholipid syndrome.
Madrid, Spain. January.
Krillis S. Invited participant. FXI is a substrate for
oxidoreductases: enhanced activation of reduced FXI
and its role in Antiphospholipid syndrome thrombosis.
Haemostasis.
Gordon Research Conference. Water Valley, New
Hampshire, USA. July.
Krillis S. Recent developments in the pathogenesis of
Antiphospholipid syndrome. Autoimmunity symposium
University of Athens, Athens, Greece, September.
Krillis S. Invited speaker. The role of oxidative
modification of Beta 2GPI induction of autoantibodies
in the Antiphospholipid syndrome. Department of
Rheumatology, Clinical Immunology Series, Beth Israel
Hospital, Harvard Medical School, USA, October.
2012 - National
Krillis S. Invited speaker. The role of mast cells in innate
immunity. 3rd Australasian Wound and tissue Repair
Society and 9th Australasian Society for Dermatology
Research. National conference. Sydney, May.
Krillis S. Session Chair – Autoimmunity and Allergy. 3rd
Australasian Wound and Tissue Repair Society and 9th
Australian Society for Dermatology Research, May.
Conway DP, Guy R, Davies SC, Couldwell DL, McNulty
A, Smith DE, Cunningham P, Keen P, Holt M. Rapid
HIV testing is acceptable and preferred among gay
men attending sexual health clinics: findings from the
Sydney rapid testing study (Oral). Australasian HIV/AIDS
Conference, Melbourne 17-19 October.
Conway DP, Holt M, McNulty A, Couldwell DL, Smith DE,
Davies SC, Cunningham P, Keen P, Guy R. Operational
performance of the Determine HIV Combo rapid test
when used to test gay and bisexual men for HIV in
Sydney sexual health clinics (Oral). Australasian HIV/AIDS
Conference, Melbourne 17-19 October.
Bavinton B, Conway D, Keen P, Guy R, Prestage G. Which
gay men would use home HIV testing (Oral)? Australasian
HIV/AIDS Conference, Melbourne 17-19 October.
Causer LM, Kuramop M, Karapanagiotidis T, Ryan C,
Wand H, Conway D, Denham I, Anderson D, Robertson
P, Leslie D, Donovan B, Fairley C, Kaldor J, Guy R.
Laboratory evaluation of five point-of-care tests for the
diagnosis of syphilis (Oral). 13th International Union
against Sexually Transmitted Infections (IUSTI) World
Congress, Melbourne 15-17 October 2012.
2013 - International
Krillis S. Invited Speaker . Posttranslational forms of B2GPI
in diabetic complications. 2013 International Diabetes
Summit Forum, Tianjin, China.
Krillis S. Invited speaker and member of organising
committee 1. Post-translational modification of B2GPI
in the antiphospholipid syndrome: implications for
autoantibody formation, 2. Chairman; treatment of
thrombosis in the antiphospholipid syndrome. XIV
International Congress on Antiphospholipid Antibodies,
Rio De Janeiro, Brazil, October.
Krillis S. Invited speaker. The role of oxidation of
complement control proteins in human inflammation.
Brigham and Women’s Hospital, Harvard Medical School
Seminar Programme, Boston, USA, July.
Krillis S. Invited speaker. The role of oxidative posttranslational modification of B2GPI in patients with
the antiphospholipid syndrome. Seminar Programme
Rockefeller University, July.
Krillis S. Invited speaker. Diagnostic tests in the
antiphospholipid syndrome: post-translational forms of
B2GPI using novel ELISAs. Instrumentation Laboratories
the Werfen Group. Boston, USA, May.
Konecny P,. Adhikari SA, Choo L K V, Patil M, Duflou J,
McWhinney B, Pretorius C, Weatherall C.J. Parenteral
Ivermectin Pharmacology in Strongyloidiasis: Postmortem Analysis (Oral). 53rd Interscience Conference on
Antimicrobial Agents and Chemotherapy (ICAAC) Denver,
Sept 10-13.
Conway DP, Holt M, McNulty A, Couldwell DL, Smith DE,
Davies SC, Cunningham P, Keen P, Guy R on behalf of the
Sydney Rapid HIV Test study. Field performance of the
Alere Determine HIV Combo assay in a large Australian
multi-centre study in a sexual health clinic setting. STI &
AIDS World Congress 2013, Vienna July 14-17.
Conway DP, Guy R, McNulty A, Couldwell DL, Davies SC,
Smith DE, Keen P, Cunningham P, Holt M. Experience of
rapid HIV testing increases its acceptability to clinical staff
in public sexual health clinics in Sydney (Poster). STI &
AIDS World Congress 2013, Vienna July 14-17.
2013 - National
Conway DP. Rapid HIV Testing in Australia (Oral - invited
speaker). Australasian HIV/AIDS Conference, Darwin 21-23
October.
Conway DP, Holt M, McNulty A, Couldwell DL, Smith
DE, Davies SC, Cunningham P, Keen P, Guy R. Field
performance of the Alere Determine HIV Combo assay
in recent HIV infection and overall in the Sydney Rapid
HIV Test Study (Oral). Australasian HIV/AIDS Conference,
Darwin 21-23 October 2013.
Conway DP, Guy R, McNulty A, Couldwell DL, Davies SC,
Smith DE, Keen P, Cunningham P, Holt M. Effect of testing
experience and profession on staff acceptability of rapid
HIV testing in public sexual health clinics in Sydney (Oral).
Australasian HIV/AIDS Conference, Darwin 21-23 October
2013.
Conway DP, Guy R, Atkinson M, Marshall L, McCloskey
J, Langdon P, Callander D, Jamil MS, Holt M. Clients at
M Clinic, a novel community/peer-worker based clinical
service targeting gay and bisexual men, prefer nontraditional methods for HIV/STI testing and result delivery
(Poster). Australasian Sexual Health Conference, Darwin
23-25 October 2013.
Cunningham PH, Leeman C, Cornwall J, Conway D, Guy
R, Kelleher AD. Sensitivity evaluation of six rapid tests for
detection of Human Immunodeficiency Virus Infection
(Oral). Australasian HIV/AIDS Conference, Darwin 21-23
October 2013.
Couldwell D, Biggs K, Townsend J, Conway D, Keen P,
Holt M, Guy R. Reasons why men decline rapid HIV testing
(Poster). Australasian HIV/AIDS Conference, Darwin 21-23
October 2013.t
Robinson S. and Weatherall, C. Poster Presentation,
“Eviplera: a case or two for switching” abstract presented
at 2013 Australasian HIV conference, Darwin.
29
Awards
NSW Health Awards
2013 Annual NSW Health Innovation Award for Integrated
Health Care: “Bug Attack - St George Hospital Fight Back:
Confronting Resistance” Antimicrobial Stewardship Team
2008-2012, Department Infectious Diseases, Immunology
& Sexual Health.
2013 NSW Minister’s Award for Doctors-in-Training
Winner: Advanced Trainee Infectious Diseases, Dr
Catherine Berry , Department Infectious Diseases,
Immunology & Sexual Health.
30
>
Department of Intensive Care,
St George Hospital
Head of Department
A/Prof Theresa Jacques MBBS (Hons) FANZCA FCICM
MHL, Director, Department of Intensive Care, Conjoint
Associate Professor University of New South Wales,
Donation Specialist -Medical DONATE LIFE NSW
Senior Medical
Dr Kush Deshpande MBBS, MD, FCICM, Deputy Director,
Department of Intensive Care Unit, Senior Staff Specialist ,
Conjoint Lecturer, St George Clinical School, UNSW
Professor John Myburgh MBBCh PhD FANZCA FCICM
FAICD (Head of Research (Program), Professor of Critical
Care Medicine, University of New South Wales, Director,
Division of Critical Care & Trauma, George Institute for
Global Health, Honorary Professor, University of Sydney,
Honorary Adjunct Professor, Monash University
A/Professor George Skowronski MMBS (Hons),
FRCP,FRACP, FCICM, Conjoint Associate Professor, Critical
Care, UNSW
A/ Prof Konstantin Yastrebrov MBBS (Hons) PhD FCICM
FACRRM DDU , Conjoint Associate Professor University
of NSW, Senior Honorary Fellow, The University of
Melbourne.
Dr Doris Lam FCICM, FANZCA, MBChB, Conjoint Lecturer,
St George Clinical School, UNSW
Dr Manoj Saxena MRCP, FRACP, F.J.F.I.C.M, F.C.I.C.M,
M.B. B. Chir, Bsc (Hons)
(Deputy to Head of Research Program), Conjoint Lecturer,
St George Clinical School, UNSW
Dr Andrew Cheng BHB, MBChB (NZ), FCICM, Hospital
Medical Director – Organ and Tissue, Conjoint Lecturer, St
George Clinical School, UNSW, Director Organ and Tissue
2012, Donation Specialist -Medical DONATE LIFE NSW
Dr Carton Costello MB BCH BAO, FCICM, FACRRM,
FRACGP, BA Com, Grad Dip Crit Care Echo, Donation
Specialist –
Medical DONATE LIFE NSW , Director Organ and Tissue
2013, Conjoint Appointee, USNW
Visiting Medical Officers
Dr Asako Ito B Med, FCICM
Dr Atul Gaur MBBS, MD, FRCA, FCICM
Dr Barbara Trytko, BMBS, FANZCA, FFICANZA, FCICM
Dr Monique Leijten, MD, EDIC FCICM
Dr Marek Nalos, MBBS, PhD, EDIC, FCICM
Dr Mathew Macpartlin, MBBS, MRCPI, FACEM, FCICM
Dr Nhi Nguyen MBBS, B Med Sc, FCICM
Dr Paris Jain MBBS, MD, EDIC, FCICM
Dr Razavian Maziar, MBBS, FCICM
Junior Medical Officers - Senior Registrars
Dr Kiran Deol MBBS
Dr.Mahadev Patil
Dr Menaka Perumbuli Achchige MBBS, MD Anaesthesia
Dr Rosalba Cross
Dr Raju Pusapati
Dr Swapnil Pawar MBBS, MD
Dr Syed Ali MBBS,MD
Dr.Tejo Kapalli MBBS, MD, FCICM
Research Staff
Saxena MK PhD Candidate
Hammond N PhD Candidate
Nair P PhD Candidate
Willenberg L MPhil Research
Liu A MBBS BSc (Medicine)
Bass F MPhil Candidate
Liang S MBBS Candidate
Miller J Graduate Certificate in in Clinical Research
Research Assistants
Deborah Inskip, BSc, Grad Cert Crit Care, CNS, Quality,
Education, Research and Information Officer, Research
Coordinator
Jennene Miller, BSc, Grad Cert Crit Care, Grad Cert Clin
Research, CNS, Research Coordinator
Rebecca Sidoli, Dip Apl Sc, ICU Cert, CNS, Quality,
Education, Research and Information Officer
Amy Liu, B.Sc. (1st Class Honours), University of NSW
Medical Student 2012
Sophie Liang, University of Sydney Medical Student 2013
Nursing & Allied Health
Sarah Jones RN, Grad Cert ICU, Grad Dip Education, CNC
Suman Adhikari, Bpharm, Grad Dip Clin Pharm ICU
Pharmacist
Wendy Chaseling B.App.Sc. (physio), M.Ed. M.Hth.Sc
(physio) M.A.P.A. APA Cardiorespiratory Physiotherapist,
Senior ICU Physiotherapist
31
Theodora Bikou BSW Senior Social Worker ICU
Dallas Nolan BSW Social Worker ICU2
Warren Eather, Clinical Data Manager
Kylie Fraser. BappSc OT, Manager St George Clinical Skills
Centre.
Intensive Care Foundation, Vitamin D dosing study in
intensive care unit patients with the systemic inflammatory
response syndrome, Principal Investigators: Nair P,
Venkatesh B, Center J, Myburgh J.A, Krishnan A. $29 000;
2013-2014.
Research Grants
Nursing & Midwifery Strategy Funding, Study of
Communication Practices I ICU, Principal Investigators: S
Jones, J Bothe, $9000.
NHMRC, A randomised controlled trial of prophylactic
hypothermia in severe traumatic brain injury (POLAR trial)
(Project Grant: 545901) Principal Investigators: Cooper
D.J. Bernard S, Nichol A., Presneill J, Cameron P, Myburgh
JA, $1.95M; 2009-2013.
NHMRC, The Crystalloid vs Hydroxyethyl starch Trial.
(CHEST) (Project Grant: 632503) Principal Investigators:
Myburgh J.A. Finfer S.R, Bellomo R, Lipman J, Webb S.R,
Liu B. $2.1M; 2010-2014.
NHMRC, National Centre for Intensive Care research
(Enabling grant extension: 606978) Principal Investigators:
Bellomo R, Myburgh J.A. Finfer SR, Cooper DJ, $2.5M;
2010-2015.
NHMRC, A phase IIB randomised controlled trial
of continuous beta-lactam infusion compared with
intermittent beta-lactam dosing in critically ill patients
(BLING) (Project Grant: 1022460) Principal Investigators:
Lipman J, Webb S, Dulhunty J, Paterson D, Roberts J,
Myburgh J.A. (Associate Investigator) $915 978; 20122017.
NHMRC, Practitioner Fellowship (1020204) Principal
Investigator: Myburgh J.A. $374 220; 2012-2016.
Honda Corporation to St George Medical Research
Foundation, The Honda Foundation Trauma and Critical
Care Research Program, Principal Investigators: Myburgh
J.A, Langcake M, Curtis K, Saxena M. $150 000; 20112013.
Fresenius Kabi to University of Sydney / The George
Institute for Global Health, The Crystalloid vs Hydroxyethyl
starch Trial. (CHEST), Principal Investigators: Myburgh J.A.,
MacMahon S. $7.6M; 2008-2012.
Health Research Council of New Zealand, A placebocontrolled trial of paracetamol in febrile patients with
severe sepsis. (HEAT study). Principal Investigators:
Beasley R, Young P, McGuinness S, Freebairn R, Van Haren
F, Henderson S, McArthur C, Bellomo R, Myburgh J.A,
Saxena M, Webb S, Weatherall M. NZ$1.2M; 2012-2014.
Health Research Council of New Zealand, Randomised trial
of hydrocortisone in critically ill patients with septic shock
(ADRENAL) Principal Investigators: McArthur C, Venkatesh
B, Young P, McGuinness S, Williams A, Freebairn R,
Henderson S, Finfer S, Myburgh J.A. NZ$773 854; 20122016
Research Projects in Progress
A retrospective audit of practice of Total Parenteral
Nutrition (TPN) at a major teaching hospital in Australia.
Principal Investigators: Patil M, Macintrich I, Scoolbread E,
Wilson V, Deshpande K.
ADRENAL, (Adjunctive corticosteroid treatment in critically
ill patients with septic shock. Principal Investigators:
Myburgh J Saxena M.K.
Intensive Care Foundation The ANZICS Clinical Trials
Group Point Prevalence Program, Principal Investigators:
Seppelt I, Webb S, McArthur C, Elliot R, Myburgh JA,
Glass P, Taylor C. $31 000; 2012.
Antimicrobial Stewardship in Intensive Care Unit: Is it
possible to demonstrate achievement of all Primary Goals?
Principal Investigators: Adhikari S, Konecny P, Taylor P, Piza
M, Lam D, Deshpande K.
Australian and New Zealand College of Anaesthetists.
An exploratory study of perceived risks, benefits and
barriers to the use of Selective Decontamination of the
Digestive Tract in Australasian ICUs (SuDDICU), Principal
Investigators: Seppelt I, Marshall A, Myburgh JA, Lipman
J, Francis G, Cuthbertson B, Glass P. $40 000; 2012-2013.
BLING ll, (Beta-Lactam Infusion Group), Principal
Investigators: Cheng A, Saxena M.K, Adhikari S
Intensive Care Foundation, A randomised placebocontrolled trial of intravenous paracetamol in febrile
patients (HEAT Study), Principal Investigators: Beasley
R, McGuiness S, Freebairn R, Van Haren F, McArthur C,
Bellomo R, Myburgh J.A, Saxena M, Webb S, Weatherall
M, Henderson S. $20 000; 2013-2014.
Characteristics and predictors of mortality in elderly
patients (≥ 85 years) admitted to a tertiary ICU in Australia,
Principal Investigators: Kapalli T, Deshpande K.
32
CELCIUS, (Comparison of core and peripheral temperature
measurement in adult critically ill patients with brain
injury). Principal investigators: Liu A, Saxena M.K, Myburgh
J, Miller J, Inskip D.
COMFORT – Communication with families regarding
Organ and Tissue Donation after Death in ICU, Principal
Investigatosr: A Cheng A, Costello C.
CHEST, (Crystalloid versus Hydyroxyethyl Starch Trial),
Principal investigators: Myburgh J.A, Saxena M.K.
Topic: Early temperature elevation and functional survival
at 24 months after traumatic brain injury: Retrospective
analysis of the multi-centre cohort of the SAFE trial. ,
Principal investigatosr: Liang S, Saxena M.K, Finfer S,
Billot L, Myburgh J.A
HEAT, (Permissive Hyperthermia Through Avoidance
of Paracetamol in Known or Suspected Infection in ICU
Principal Investigators: (Co-Chief Investigator - Saxena
M.K), Myburgh J.A
Family Satisfaction Survey, Principal Investigators:
Achchige M, Deshpande K, Jacques T, Bikou T, Nolan D.
Nephro Protective Trial, (Nephroprotective effects of L
amino acids in critically ill patients), Principal investigator:
Jacques T.
PARITY, (The Paracetamol after Traumatic Brain Injury
study), Principal investigators: Saxena M.K, Taylor C,
Myburgh J.A. Glass P, Gowardman J, Lipman J.
Sodium Balance Study, Principal Investigators: Saxena
M.K, Miller J, Inskip D.
Study of Communication Practices in ICU, Principal
Investigators: S Jones, J Bothe.
TEAM, (Trial of Early Activity and Mobilisation), Principal
Investigators: Saxena M.K. Chaseling W.
The SANITY Survey - A Survey of Temperature
Management After Traumatic Brain Injury - Evaluating the
Potential Role of NSAIDs. Principal Investigators: Deol K,
Saxena M.K, Myburgh J.A.
TTM, (Target Temperature Management after Cardiac
Arrest Trial), Principal investigators: Saxena M.K, Myburgh
J.A.
TRANSFUSE, (Standard Issue Transfusion versus
Fresher Red Blood cells use in Intensive Care), Principal
Investigators: Deshpande K, Saxena M.K.
Original Peer-Reviewed Publications
2012
Cheung W., Myburgh J.A., Seppelt I., Parr M.J.,
Blackwell N., DeMonte S., Ghandi K., Hoyling L., Nair
P., Passer M., Reynolds C., Saunders N.M., Saxena M.K.,
Thanakrishnan G for the Influenza Pandemic ICU Triage
Study Investigators. Development and evaluation of an
influenza pandemic ICU triage protocol. Critical Care and
Resuscitation, 2012; 14:185-189.
Cheung W., Myburgh J.A., Seppelt I., Parr M.J.,
Blackwell N., DeMonte S., Ghandi K., Hoyling L., Nair
P., Passer M., Reynolds C., Saunders N.M., Saxena M.K.,
Thanakrishnan G for the Influenza Pandemic ICU Triage
Study Investigators. A multicentred evaluation of two
Intensive Care Unit triage protocols for use in an influenza
pandemic. Medical Journal of Australia, 2012; 197: 178181.
Dulhunty J., Roberts J., Davis J., Webb S., Bellomo R.,
Gomersall C., Shirwadkar C., Eastwood G., Myburgh J.A.,
Paterson D., Lipman J. (2013). Continuous infusion of betalactam antibiotics in severe sepsis: a multicentre, doubleblind, randomised controlled trial. Clinical Infectious
Diseases 56: 236-244.
Gattas D., Dan A., Myburgh J.A., Lo S., Billot L., Finfer
S for the CHEST Management Committee. Fluid
resuscitation with 6% Hydroxyethyl starch (130/0.4) in
acutely ill patients – an updated systematic review and
meta-analysis. Anaesthesia and Analgesia, 2012; 114: 159169.
Myburgh J.A., Li Q., Heritier S., Dan A., Glass P for the
Crystalloid versus Hydroxy-Ethyl Starch Trial Management
Committee. ‘Statistical analysis plan for the Crystalloid
versus Hydroxy-Ethyl Starch Trial. Critical Care and
Resuscitation, 2012; 14: 44-52.
Myburgh J.A. (2012). The role of hydroxyethyl starch for
resuscitation in the ICU. Critical Care and Resuscitation,
2012; 14:251 (Editorial).
Peake S., Chapman M., Davies A., Moran J., O’Connor S.,
Ridley E., Williams P for the George Institute for Global
Health and the Australian and New Zealand Intensive
Care Society Clinical Trials Group. (Myburgh J.A.:
Principal Investigator: St George Hospital; Management
Committee Point Prevalence Program). Enteral nutrition in
Australian and New Zealand Intensive Care Units: a point
prevalence study of prescription practices. Critical Care
and Resuscitation, 2012; 14:158-153.
Skowronski GA, Peisah C. The greying intensivist: ageing
and medical practice - everyone’s problem. Med J Aust.
2012 May 7;196 (8):505-7.
The RENAL Study Investigators. (Myburgh J.A.: Member
Writing Committee). Fluid balance and patient outcomes
in the Randomised Evaluation of Normal vs Augmented
Level of renal replacement therapy trial. Critical Care
Medicine, 2012; 40: 1753-1760.
Taylor C., Jan S., Curtis K., Tzannes A., Li Q., Palmer
C., Dickson C., Myburgh J.A. The cost-effectiveness of
physician-staffed hospital emergency medical service
(HEMS) transport to a major trauma centre in NSW,
Australia. Injury, 2012; 43: 1843-1849.
Taylor C., Jan S., Myburgh J.A. Exploring the economics of
helicopter rescue in Australia. Medical Journal of Australia,
2012; 197: 488-490.
33
Taylor C., Liu B., Bruce E., Burns B., Jan S., Myburgh
J.A, Primary scene responses by Helicopter Emergency
Medical Services in New South Wales, Australia 20082009. BMC Health Services Research, 2012; 12:402
St George Hospital). Sodium administration in critically ill
patients in Australia and New Zealand: a multicentre point
prevalence study. Critical Care and Resuscitation, 2013;
15: 294-300.
Willenberg L., Curtis K., Taylor C., Jan S., Glass P.,
Myburgh J.A. Variation of acute treatment costs of trauma
in high-income countries. BMC Health Services, 2012; 12:
267.
Bradford C., Finfer S., O’Connor A., Yarad E., Firth R.,
McCallister R., Harrington T., Steinfort B., Faulder K.,
Assaad N., Morgan M. (Myburgh J.A.: Chair: Data
Monitoring Committee). A randomised-controlled trial
of induced hypermagnesaemia following aneurysmal
subarachnoid haemorrhage. Critical Care and
Resuscitation, 2013; 15: 119-125.
Yastrebov K, Sader M, Youssef G, et al. Dynamic
Echocardiography in Evaluation of Platypnea-Orthodeoxia.
AJUM: 2012 May 15(2)72-76.
Young P., Hodgson C., Dulhunty J., Saxena M., Bailey
M., Bellomo R., Davies A., Finfer S., Kruger P., Lipman
J., Myburgh J.A., Peake S., Seppelt I., Streat S., Tate R.,
Webb S for the ANZICS Clinical Trials Group. Endpoints
for phase II trials in intensive care: recommendations from
the Australian and New Zealand Intensive Care Society
Clinical Trials Group consensus panel meeting. Critical
Care and Resuscitation, 2012; 14:211-215.
Young P., Saxena M., Beasley R., Bellomo R., Bailey M.,
Pilcher D., Finfer S., Harrison D., Myburgh J.A., Rowan
K. Early peak temperature and mortality in critically
ill patients with and without infection. Intensive Care
Medicine, 2012; 38: 437-444.
Young P., Saxena M., Andrews L., Bellomo R., Freebairn
R., Henderson S., McArthur C., McGuinness S., Mackle
D., Myburgh J.A., Van Haren F., Weatherall M., Webb S.,
Beasley R and the ANZICS Clinical Trials Group. The HEAT
trial: a protocol for a phase IIb multi-centre randomised
placebo-controlled trial of intravenous paracetamol in
intensive care patients with fever and infection. Critical
Care and Resuscitation, 2012; 14:290-296 [Correction:
Critical Care and Resuscitation 2013: 15: 133].
2013
Barker CL, Costello C, Clarke PT. Obstetric Air Medical
Retrievals in the Australian Outback. Air Medical Journal
2013, 32(6): 329-33.
Bellomo R., Lipscey M., Calzavacca P., Haase M., HaaseFelitz A., Licari E., Cole L., Cass A., Finfer S., Gallagher M.,
Lee J., Lo S., McArthur C., McGuiness S., Myburgh J.A.,
Scheinkestel C for the RENAL Study Investigators and the
Australian and New Zealand Intensive Care Society Clinical
Trials Group. Early acid-base and blood pressure effects of
continuous renal replacement therapy intensity in patients
with metabolic acidosis. Intensive Care Medicine, 2013;
39: 429-326.
Bihari S., Peake S., Seppelt I., Williams P., Bersten A.,
on behalf of the George Institute for Global Health and
the Australian and New Zealand Intensive Care Society
Clinical Trials Group. (Myburgh J.A.: Principal Investigator,
34
Cooper D.J., Myburgh J.A., Bellomo R., Billot L., Finfer
S., Heritier S., Murray L., Vallance S., for the SAFETBI Investigators and the Australian and New Zealand
Intensive Care Society Clinical Trials Group. Albumin
resuscitation for traumatic brain injury – is intracranial
hypertension the cause of increased mortality? Journal of
Neurotrauma, 2013; 30: 512-518.
Dulhunty J., Roberts J., Davis J., Webb S., Bellomo R.,
Gomersall C., Shirwadkar C., Eastwood G., Myburgh
J.A., Paterson D., Starr T., Udy A., Paul S., Lipman J and
the Australian and New Zealand Intensive Care Society
Clinical Trials Group and Australasian Society for Infectious
Diseases Clinical Research Network. A protocol for a
multicentre randomised-controlled trial of continuous
beta-lactam infusion compared with intermittent betalactam dosing in critically ill patients with severe sepsis:
the BLING II study. Critical Care and Resuscitation, 2013;
15:179-185.
Gattas D., Dan A., Myburgh J.A., Billot L., Lo S., Finfer
S., for the CHEST Management Committee. Fluid
resuscitation with 6% hydroxyethyl starch (130/0.4)
in acutely ill patients: systematic review of effects on
mortality and treatment with renal replacement therapy.
Intensive Care Medicine, 2013; 39: 558-568.
Hammond N., Saxena M., Taylor C., Young P., Seppelt I.,
Glass P., Myburgh J.A., for the George Institute for Global
Health and ANZICS Clinical Trials Group. Temperature
management of non-elective intensive care patients
without neurological pathology: a point prevalence study
of practice in Australia and New Zealand. Critical Care and
Resuscitation, 2013; 15:228-233.
Myburgh J.A., Finfer S. Causes of death after bolus fluid
resuscitation: new insights from FEAST. BMC Medicine,
2013; 11:67 (Editorial).
Myburgh J.A., McIntyre L. New insights in fluid
resuscitation. Intensive Care Medicine, 2013; 39: 998-1001
(Editorial).
Myburgh J.A. Advances in fluid resuscitation in critically ill
patients: implications for clinical practice. Current Opinion
in Critical Care, 2013; 19: 278-291 (Editorial).
Myburgh J.A. Review: Hydroxyethyl starch increases
mortality and acute kidney injury in critically ill patients.
Annals of Internal Medicine, 2013; 158: JC4.
Nair P., Center J., Eisman J., Nguyen N., Myburgh J.A.,
Cylee P., Reynolds C. Significant perturbation of vitamin
D-parathyroid-calcium axis and adverse clinical outcomes
in critically ill patients. Intensive Care Medicine, 2013; 39:
267-274.
Nielsen N., Wetterslev J., Cronberg T., Erlinge D., Gasche
Y., Hassager C., Horn J., Hovdenes J., Kjaegaard J., Kuiper
M., Pellis T., Stammet P., Wanscher M., Wise M., Aneman
A., Al-Subaie N., Boesgaard S., Bro-Jeppsen J., Brunetti
I., Bugge J., Hingston C., Juffermans N., Koopmans M.,
Kober L., Langorgen J., Lilja G., Moller J., Rundgren M.,
Rylander C., Smid O., Werer C., Winkel P., Friberg H for
the TTM investigators. (Myburgh J.A.: Study Director,
George Institute for Global Health, Saxena M: Site PI ).
Targeted temperature management at 33oC versus 36oC
after cardiac arrest. New England Journal of Medicine,
2013; (Published online 17 November 2013).
Parke R., Eastwood G., McGuinness on behalf of the
George Institute for Global Health and the Australian and
New Zealand Intensive Care Society Clinical Trials Group.
(Myburgh J.A.: Principal Investigator). Oxygen therapy
in non-intubated adult intensive care patients: a point
prevalence study.’ Critical Care and Resuscitation, 2013;
15: 287-293.
Saxena M.K. Taylor C., Hammond N., Young P., Seppelt I.,
Glass P., Myburgh J.A. for the George Institute for Global
Health and the ANZICS Clinical Trials Group. Temperature
management in patients with acute neurological lesions:
an Australian and New Zealand point prevalence study.
Critical Care and Resuscitation, 2013; 15: 110-118.
Venkatesh B., Myburgh J.A., Finfer S., Webb S., Cohen
J., Bellomo R., McArthur C., Joyce C., Rajbhandari D.,
Glass P., Harward M and the ANZICS Clinical Trials Group
Investigators. The ADRENAL Study protocol: Adjunctive
corticosteroid tREatment iN criticAlly iLl patients with
septic shock. Critical Care and Resuscitation, 2013; 15:
83-87.
Yastrebov K, McLean A: Establishment of Critical Care
Echocardiography Laboratory. Crit Care 2013; 17 Sup2,
S69, P184.
Yastrebov K, Kapalli T: Malposition of Double Lumen
Bicaval Venovenous Extracorporeal Membrane
Oxygenation (VV ECMO) cannula resulting in hepatic
venous congestion. AJUM, November 2013.
Young P., Weatherall M., Saxena M., Bellomo R., Freebairn
R., Hammond N., Van Haren F., Henderson S., McArthur
C., McGuinness S., Mackle D., Myburgh J.A., Webb S.,
Beasley R and the ANZICS Clinical Trials Group. The
statistical analysis plan for the HEAT trial: a multi-centre
randomised placebo-controlled trial of intravenous
paracetamol in intensive care patients with fever and
infection. Critical Care and Resuscitation, 2013; 15:279286
Other Published Material
2012
Douglas B, Morarty J, Saxena M K (2012) Traumatic
Brain Injury In: Emergency and Trauma Care for nurses
and paramedics. (Curtis K, Ramsden C). Sydney: Mosby
Elsevier. pp 1169-1192.
2013
Gordon A., Myburgh J.A. (2013). Vasodilators and
antihypertensives. In: Oh’s Intensive Care Manual 7th
edition. (Bersten A.D., Soni N. eds). London: Butterworth
Heinemann Elsevier. pp. 923-936.
Myburgh J.A., Saxena M.K. (2013). Severe Head Injury.
In: Oh’s Intensive Care Manual 7th edition. (Bersten A.D.,
Soni N. eds). London: Butterworth Heinemann Elsevier. pp.
762-776.
Myburgh J.A. (2013). Inotropes and vasopressors. In: Oh’s
Intensive Care Manual 7th edition. (Bersten A.D., Soni N.
eds). London: Butterworth Heinemann Elsevier. pp. 912922.
Skowronski G. Saxena M. (2013). Neuromuscular
Disorders. In: Oh’s Intensive Care Manual 7th edition.
(Bersten A.D., Soni N. eds). London: Butterworth
Heinemann Chapter 57.
Presentations at Scientific Meetings and
Conferences
2012 - International
Gallagher M., Bellomo R., Cass A., Gattas D., Lee J., Lo
S., McGuinness S., Myburgh J.A., Parke R. October 2012
(San Diego, USA). Long term outcome of severe AKI: the
results of the POST-RENAL study. American Society of
Nephrology: Kidney Week 2012.
Hammond N., Saxena M.K. Young P., Taylor C., Seppelt
I., Glass P., Myburgh J.A. Temperature management
for patients without brain injury in Australia and New
Zealand Intensive Care Units: a point prevalence survey. A
survey of fever management in febrile critically ill patients
without neurological injury. 32nd International Symposium
on Intensive Care and Emergency Medicine Brussels,
Belgium. March.
Myburgh J.A. The case for randomised-controlled trials for
fluid resuscitation. Round Table Conference: International
Symposium on Intensive Care and Emergency Medicine.
Brussels, Belgium. March.
35
Myburgh J.A. Report of the Round Table Conference:
Types of intravenous fluids. International Symposium
on Intensive Care and Emergency Medicine. Brussels,
Belgium. March.
Care Forum. Toronto, Canada, November.
Yastrebov K. Visiting Professor in Intensive Care,
Hospital Ambroise Pare. Paris, France, June.
Myburgh J.A. The CHEST study. International Symposium
on Intensive Care and Emergency Medicine. Brussels,
Belgium. March.
Willenberg L., Curtis K., Taylor C., Jan S., Glass P.,
Myburgh J.A. Variation of acute treatment costs of trauma
in high-income countries. London Trauma Conference.
London, UK, November.
Myburgh J.A. I believe in adrenaline. International
Symposium on Intensive Care and Emergency Medicine.
2012 - National
Myburgh J.A. The Crystalloid vs Hydroxyethyl Starch Trial.
11th Congress in Evidence Based Perioperative Medicine
and the Great World Fluid Debate. London, UK July.
Myburgh J.A. Unanswered questions in fluid management.
11th Congress in Evidence Based Perioperative Medicine
and the Great World Fluid Debate. London, UK July.
Myburgh J.A. Fluid resuscitation with 6% HES (130/0.4)/
vs normal saline: The CHEST trial. Hot topics session:
European Society of Intensive Care Medicine Annual
Scientific Meeting. Lisbon, Portugal, October.
Gallagher M., Bellomo R., Cass A., Finfer S., Gattas D.,
Lee J., Lo S., McGuinness S., Myburgh J.A., Parke R.,
Rajbhandari D. Long term outcome of severe AKI: the
results of the POST-RENAL study. Australian and New
Zealand Society of Nephrology Annual Scientific Meeting.
Melbourne, August.
Ito A., Lam D., Deshpande K. Bacteraemia in Intensive
Care Unit: Temporal trends in epidemiology and
antimicrobial susceptibility. College of Intensive Care
Medicine Annual Scientific Meeting. Melbourne, June.
Myburgh J.A. The CHEST trial. Critical Care Canada
Forum. Toronto, Canada, October.
Myburgh J.A. Sustainable Intensive Care. Bush Track to
Boulevard: College of Intensive Care Medicine Rural and
Regional Meeting. Byron Bay, March.
Myburgh J.A. Pressors, inotropes and fluids: do our
choices really matter? Critical Care Canada Forum
Residents’ Day. Toronto, Canada, October.
Myburgh J.A. CHEST update. Australian and New
Zealand Intensive Care Society Clinical Trials Group Annual
Scientific Meeting. Noosa, March.
Myburgh J.A. Development of a definitive RCT of steroids
in critically ill patients. Critical Care Canada Forum.
Toronto, Canada, October.
Myburgh J.A. NICE-SUGAR TBI - results. Australian and
New Zealand Intensive Care Society Clinical Trials Group
Annual Scientific. Noosa, March.
Myburgh J.A. Fluid resuscitation in specific patient
populations: sepsis and traumatic brain injury. Critical Care
Canada Forum. Toronto, Canada, October.
Myburgh J.A. The CHEST trial results. Australian and New
Zealand Intensive Care Society Clinical Trials Group Winter
Research Forum. Melbourne, July.
Myburgh J.A. The CHEST trial. International Sepsis Forum.
Paris, France, November.
Myburgh J.A. A fluid movement in acute medicine. St
George Hospital, Malcolm Schonnel Memorial Lecture.
Sydney, February.
Myburgh J.AType of intravenous fluids. .. Conferences de
soins intensifs et de medecine d’urgence: Hopital Erasme.
Brussels, Belgium, November.
Myburgh J.A. Inotropes and vasopressors. Crit IQ:
podcast. May 2012.
Myburgh J.A. Resuscitation fluids: past, present, future.
University of Birmingham, UK, November.
Myburgh J.A. Fluid resuscitation – new developments.
Sydney Intensive Care Network, May.
Saxena M.K. Young P., Bailey M., Pilcher D., Beasley
R., Bellomo R., Finfer S., Myburgh J.A. Early peak
temperature and mortality in critically ill patients with
acute neurological pathology. Canadian Critical Care
Forum. Toronto, Canada, November.
Saxena M.K. The CLARITY study –Understanding
“normothermia” after TBI and stroke. The Clinical Trials
Group of the Australia and New Zealand Intensive Care
Society: Annual Scientific Meeting Noosa, March.
Saxena M.K. Taylor C., Hammond N., Bellapart J., Skirfvars
M., Loh A., Nayyar V., O’Leary M., Rajbandhari D., Hardie
M., Rashid A., Seppelt I., Glass P., Myburgh J.A. Defining
normothermia for traumatic brain injury: and Australian
multicentre retrospective cohort study. Canadian Critical
36
Saxena M.K. Normothermia for Acute Neurological
Pathology: is a RCT feasible / CLARITY Update. The
Clinical Trials Group of the Australia and New Zealand
Intensive Care Society: Annual Scientific Meeting
Adelaide, October.
Saxena M.K. Normothermia and Acute Brain Injury.
Nepean Hospital: Intensive Care Seminar. Sydney, April.
Saxena M.K. Establishing Early Medical Consensus …
St. George Hospital: Medical Morbidity and Mortality
Meeting Sydney, May.
Saxena M.K. Normothermia and Acute Brain Injury. St
Vincent’s Hospital: Intensive Care Seminar Sydney, June.
Saxena M.K. To Cool or Not to Cool … (Sepsis). St.
George and Sutherland Nursing Symposium. Sydney,
September.
Saxena M.K. Normothermia and Acute Brain Pathology,
St George and Sutherland Nursing Symposium. Sydney,
September.
Saxena M.K. Current Cooling Practices in Intensive Care
Normothermia and Acute). St. George and Sutherland
Nursing Symposium. Sydney, September.
Saxena M.K. The management of Traumatic Brain Injury.
Advanced Trauma Nursing Sydney, October.
Saxena M.K., Taylor C., Hammond M., Young P., Seppelt
I., Glass P., Myburgh J.A. Temperature management after
acute brain injury: a point prevalence study of practice
in Australia and New Zealand. Australian and New
Zealand Intensive Care Society Annual Scientific Meeting.
Adelaide, October.
Saxena M.K. Taylor C., Hammond N., Bellapart J., Skirfvars
M., Loh A., Nayyar V., O’Leary M., Rajbandhari D., Hardie
M., Rashid A., Seppelt I., Glass P., Myburgh J.A. Defining
normothermia for traumatic brain injury: An Australian
multicentre retrospective cohort study. Australian and New
Zealand Intensive Care Society Annual Scientific Meeting
2012. Adelaide, October.
Yastrebov K. Presenter Advanced course on Critical Care
Echocardiography. Leura, NSW, August.
2013 - International
Doolan H., Jacques T., Mackertich M., Stirling A.,
Fernandez R. May 2013, Examining the prevalence
and outcomes of patients with signs of documented
early deterioration, a comparison of two models. 8th
International Rapid Response Conference. Royal College
of Physicians, London UK.
Hammond N., Taylor C., Liu B., Finfer S., Glass P.,
Saxena M., Seppelt I., Willenberg L., Myburgh J.A. for
the Australian and New Zealand Intensive Care Society
Clinical Trials Group and the George Institute for Global
Health. May 2013. Fluid resuscitation practices in Australia
and New Zealand intensive care units – preliminary data.
College of Intensive Care Medicine Annual Scientific
Meeting. Wellington, NZ.
Hammond N., Taylor C., Liu B., Finfer S., Glass P., Saxena
M., Seppelt I., Willenberg L., Myburgh J.A. for the
Australian and New Zealand Intensive Care Society Clinical
Trials Group and the George Institute for Global Health.
October 2013. Fluid resuscitation practices in Australia
and New Zealand intensive care units. European Society of
Intensive Care Medicine Annual Scientific Meeting. Paris,
France.
Jacques T. February 2013, Introducing a bended learning
programme to front -line staff: Plenary Speaker at the
inaugural National Japanese Medical Simulation Meeting
Okinawa, Japan.
Myburgh J.A. May 2013. Why we need a definitive trial
on steroids. Chinese Society of Critical Care Medicine.
Xiamen, China.
Myburgh J.A. May 2013. Colloids in critical care: an
analysis of recent trials. Chinese Society of Critical Care
Medicine. Xiamen, China.
Myburgh J.A. June 2013. Decompressive craniectomy:
never for anything? College of Intensive Care Medicine
Annual Scientific Meeting. Wellington, NZ
Myburgh J.A. March 2013. Albumin in brain oedema.
International Symposium on Intensive Care and
Emergency Medicine. Brussels, Belgium.
Myburgh J.A. March 2013. PRO: Synthetic colloids should
be abandoned. International Symposium on Intensive Care
and Emergency Medicine. Brussels, Belgium
Myburgh J.A. March 2013. Optimal design for clinical
trials. International Symposium on Intensive Care and
Emergency Medicine Brussels, Belgium.
Myburgh J.A. March 2013. The CHEST Trial: further
analyses. International Symposium on Intensive Care and
Emergency Medicine Brussels, Belgium.
Myburgh J.A. July 2013. The evidence for the use of
vasopressors in critically ill patients. Singapore-ANZICS
Intensive Care Forum. Singapore.
Myburgh J.A. July 2013. Hydroxyethyl starch for fluid
resuscitation in critically ill patients. Singapore-ANZICS
Intensive Care Forum. Singapore.
Myburgh J.A. July 2013. The case for a definitive trial of
steroids in septic shock. Singapore-ANZICS Intensive Care
Forum. Singapore.
Myburgh J.A. August 2013. A renal-safe colloid: a pipe
dream? 11th World Federation of Intensive and Critical
Care Medicine Meeting. Durban, South Africa.
Myburgh J.A. August 2013. Should we move away from
God’s only inotrope? Adrenaline vs noradrenaline? 11th
World Federation of Societies of Intensive and Critical
37
Care Medicine Meeting. Durban, South Africa.
Myburgh J.A. August 2013. Adrenaline and noradrenaline
and the heart. 11th World Federation of Societies of
Intensive and Critical Care Medicine Meeting. Durban,
South Africa.
Myburgh J.A. August 2013. (Durban, South Africa). The
CHEST trial – further questions. 11th World Federation of
Societies of Intensive and Critical Care Medicine Meeting.
Myburgh J.A. September 2013. Our evolving knowledge
of fluid options. Baxter Satellite Meeting: European
Society of Intensive Care Medicine Annual Scientific
Meeting. Paris, France.
Myburgh J.A. September 2013. Commentary:
Computerised tight vs. conventional glycaemic control in
critically ill patients. President’s sessions: European Society
of Intensive Care Medicine Annual Scientific Meeting.
Paris, France.
Saxena M.K. Taylor C., Hammond N., Bellapart J.,
Skirfvars M., Loh A., Nayyar V., O’Leary M., Rajbandhari
D., Bradford C., Hardie M, Rashid A., Seppelt I., Glass
P., Myburgh J.A. March 2013. Defining normothermia
for traumatic brain injury: an Australian multicentred
retrospective study. 33rd International Symposium
on Intensive Care and Emergency Medicine. Brussels
Belgium.
Saxena M.K. 2013. The CHEST Study. French society of
Critical Care Medicine . Paris, France.
Saxena M.K. 2013. Future Directions for the Australia
and New Zealand Intensive Care Society. French society of
Critical Care Medicine. Paris, France.
Saxena M.K. 2013. How to understand Controversial
Sepsis Studies. French society of Critical Care Medicine.
Paris, France.
Saxena M.K. 2013 Doctor, please feed me ... I am starving
to death. The 2nd Singapore ANZICS Intensive Care
Forum, Singapore.
Saxena M.K. 2013 Fever for sepsis: better to be hot than
cool. The 2nd Singapore ANZICS Intensive Care Forum
Singapore,
Yastrebov K. March 2013. Establishing Critical Care
Echocardiography Laboratory. 33rd International
Symposium on Intensive Care. Brussels, Belgium.
Adhikari S Antimicrobial Stewardship in Intensive Care
Unit: Three year Evaluation of a Multidisciplinary Model.
Australian Society of Antimicrobials: Sydney.
Jones S Pressure Injury Prevention in the Critically Ill
Adult: 2nd Annual Reducing Avoidable Pressure injuries
Conference Melbourne.
Kapalli T, Deshpande K. Characteristics and predictors
of mortality in elderly patients (≥ 85 years) admitted
to a tertiary ICU in Australia. College of Intensive Care
Medicine Annual Scientific Meeting. Wellington, NZ, June.
Liu A., Saxena M.K, Myburgh J.A. The CELSIUS Study. St
George and Sutherland Hospitals Medical Symposium.
Sydney, October.
Myburgh J.A. Further results from the CHEST trial.
Australian and New Zealand Intensive Care Society Clinical
Trials Group Annual Scientific Meeting. Noosa, March.
Myburgh J.A. Fluid resuscitation: which, when and how
much? SMACC: Social media and Critical Care. Sydney,
March.
Myburgh J.A. Catecholamines: resuscitation or
resurrection: fact or fiction. SMACC: Social media and
Critical Care. Sydney, March.
Myburgh J.A. Fluid resuscitation. Royal Prince Alfred
Hospital. Sydney, November.
Saxena M.K. A protocol for a conservative fluid
randomised clinical study. The Clinical Trials Group of the
Australia and New Zealand Intensive Care Society: Annual
Scientific Meeting. Melbourne, August.
Saxena M.K. Core Outcome Measure Sets for Critical
Care Trials: a report from the International Sepsis Forum/
International Forum of Acute Care Triallists
Colloquium. The Clinical Trials Group of the Australia and
New Zealand Intensive Care Society: Annual Scientific
Meeting. Melbourne, August.
Saxena M.K. Does a conservative fluid strategy compared
to “Usual fluid management” improve outcomes for
critically ill patients? The Clinical Trials Group of the
Australia and New Zealand Intensive Care Society: Annual
Scientific Meeting. Noosa, March.
Saxena M.K Current and future fluid trials in resuscitation,
Australia and New Zealand Intensive Care Society,
Australian College of Critical Care Nurses, Annual
Scientific Meeting. Hobart, October.
Yastrebov K. March 2013. Instructor: Basic and Advanced
Courses on Critical Care Echocardiography. Brussels,
Belgium.
Saxena M.K. The importance of corporate + philanthropic
support in improving the health of patients in Australia and
New Zealand. Intensive Care Foundation, Feburary.
2013 - National
Seppelt I., Marshall A., Dan A., Cole L., Weisbrodt L.,
38
Glass P., Myburgh J.A., Finfer S., Lipman J., Francis J.,
Cuthbertson B. An international Delphi study examining
the perceived risks, benefits and barriers to the use of
selective decontamination of the digestive tract (SDD) in
intensive care. Australian Society of Infectious Disease
Annual Scientific Meeting. Canberra, March.
Shiner E, Hersch M, Yastrebov K, Normal CSF in HSV
Enchephalitis. Proceedings of the Australian and New
Zealand Association of Neurology Annual meeting.
Community Engagement
Wendy Chaseling
Chair ICCMU/ACI - Best Practice Group -Suctioning
the Artificial Airway of the Adult ICU patient: A Clinical
Practice Guideline
A/Prof Theresa Jacques
Chair Medical Staff Council St George Hospital
Chair Medical Staff Council Executive Council SESLHD
Member Clinical Council The St George Hospital
Co-Chair ICCIS Workgroup ACI /Ministry of Health
Member ANZICS End of Life Care work group
Chief Editor DETECT
Donation Specialist -Medical DONATE LIFE NSW
ICCIS PROJECT
http://vimeo.com/
user19020418review/71555501/14629d34f3
Excellence in Clinical Collaboration: The ICCIS Project
http://vimeo.com/
user19020418review/91390334/00ca3802e0
Jacques T, Morris R, Fraser K. Debrief for Health Care
Professionals involved in DETECT June 2013
Sarah Jones
Chair ISCN (Intensive Care Services Network) Best Practice
Group
Professor John Myburgh
Member, Academic Council, St George Clinical School
Member: Scientific Advisory Committee, St George
Medical Research Foundation
President, College of Intensive Care Medicine
Practitioner Fellow: National Health and Medical Research
Council
Council Member, World Federation of Societies of
Intensive and Critical Care Medicine
Malcolm Schonell Medal, St George Hospital 2012
Honour Roll, Australian and New Zealand Intensive Care
Society 2013
St George Clinical School Research Excellence Award,
University of New South Wales 2013
International collaborations
1. Round Table Conference: Types of intravenous fluids. International Symposium on Intensive care and
Emergency Medicine. (Chairman). Brussels. 2012.
2. Faculty of Intensive Care Medicine, United Kingdom.
Board retreat. (Invited international expert). London.
2012.
3. Intracranial pressure monitoring in traumatic brain
injury Think Tank: BEST TRIPS collaborative. Seattle.
2013.
4. Acute Dialysis Quality Initiative (ADQI XII): 12th Consensus Conference: Across the oceans in 2013:
the fluid debate rages on. London. 2013.
5. Global Fluid Management: Advisory Board Meeting to
Baxter Pharmaceuticals. Paris. 2013.
National collaborations
1. Clinical Trials Research Summit: The Medical Journal
of Australia. Sydney. 2012.
2. Advisory Board to Baxter Pharmaceuticals:Intravenous
Fluids. Sydney. 2013
Dr Manoj Saxena
Honorary Fellow, Critical Care & Trauma Division, The
George Institute for Global Health
Chair: Scientific Committee – St. George and Sutherland
Medical Research Symposium
Committee Member: St. George and Sutherland Medical
Research Symposium
Executive Committee Member for NSW: Australia and
New Zealand Intensive Care Society Clinical Trials Group
Examiner: College of Intensive Care Medicine
1.
“The CICM Examination Process from the Perspective of an Examiner”
a. The Wellington Intensive Care Medicine Course (2012 and 2013)
b. The Nepean Hospital Written Examination course (2012)
2.
Sydney Long Course in Intensive Care Medicine (2012 and 2013)
3.
Sydney Short Course in Intensive Care Medicine (2012 and 2013)
4.
Nepean Written Course in Intensive Care Medicine (2013)
39
5.
The Trek for Trauma (Kokoda Track, Papua New Guinea, June 2013): St George and Sutherland Medical Research Foundation
6.
“A Long Walk Back” (ABC Documentary): (http://
www.abc.net.au/austory/specials/longwalkback/
default.htm) St. George and Sutherland Medical Research Foundation
7.
“The importance of corporate + philanthropic support in improving the health of patients in Australia and New Zealand”. Intensive Care Foundation (Sydney, Feb 2013)
A/ Prof Konstantin Yastrebrov
Member of Steering Committee for Postgraduate Diploma
of Echocardiography.
Kylie Fraser
Clinical Skills Centre Executive Member, Member Editorial
Panel DETECT programme.
40
>
Department of Nuclear Medicine
Head of Department
Dr Patrick Butler MA, MD, MBA, FRACP
Conjoint Associate Professor UNSW
Senior Medical
Dr Scott Beuzeville BMed(Hons), FRACP
Dr Richard QuinnMBBS, DDU, FRACP
Dr Ramy Nour MBBS, FRACP
Junior Medical
Dr Rosamma Bency MBBS
Dr Parameswar Rachumulla MBBS
Physicists
Dr Erin McKay PhD, MACPSEM
Mr Casper Marciniak MSc, MACPSEM
Radiochemist
Ms Effie Browne BAppSci, MScMed
Medical Radiation Scientists
Mr Peter McConachie BAppSci, MCom
Mr Andrew Cluff BAppSci, MBA
Presentations at Scientific Meetings and
Conferences
2012 – National
McKay E. SPECT Quantitation of Lu-177. ANZSNM Annual
Scientific Meeting, Melbourne, April 2012.
Browne E, McKay E, Smart RC. Radiation Safety
Precautions with 177Lu-Octreotate therapy. ANZSNM
Annual Scientific Meeting, Melbourne, April 2012.
R Bency, E McKay, D Farlow, Comparison of Ga-68
Dotatate scanning and Lu-177 Dotatate scanning in NET
patients undergoing PRRT. ANZSNM Annual Scientific
Meeting, Melbourne, April 2012.
2013 – National
McKay E. Individual Variation in Renal Dosimetry of Lu-177
Octreotate. ANZSNM Annual Scientific Meeting, Perth,
April 2013.
Marciniak C, McKay E. Implementation of a Channelised
Hotelling Observer. ANZSNM Annual Scientific Meeting,
Perth, April 2013.
Research Projects in Progress
Quantitation of Lu-177 Dotatate uptake in the treatment
of neuroendocrine tumours. Principal Investigator: Dr Erin
McKay.
Reproducibility of isotopic GFR measurements. Principal
Investigator: Dr Patrick Butler.
41
>
Department of Renal Medicine
Head of Department
Professor Mark Brown
MBBS, MD, FRACP (Professor of Medicine, UNSW)
Senior Medical
Associate Professor John Kelly MBBS, MD, FRACP
Associate Professor George Mangos MBBS, MD, FRACP
Associate Professor Ivor Katz MD, MBBCh, FCP(SA), BSc
Honours, PhD, FRACP
Dr Sharon Ong BSc(Med), MBBS, PhD, FRACP (Conjoint
Senior Lecturer, UNSW)
Dr William Chan MBBS, PhD, FRACP
Dr Parthasarathy Shanmugasundaram MBBS, DM, FRACP
(Conjoint Lecturer, UNSW)
Dr Cathie Lane B.Pharm. B.Med FRACP,Grad Cert ULT,
PhD (Conjoint Lecturer, UNSW)
Dr Frank Brennan MBBS, FRACP, FAChPM, LLBConsultant Palliative Care Medicine
Research
Research Fellow
The role of cortisol in the development of hypertension
and cardiovascular disease in chronic kidney disease
$75 000, 2012.
SESLHD Chronic Care Service Redesign Grant, A/Prof Ivor
Katz
The development of a web-based Chronic Kidney Disease
Outreach Program $15 000, 2012.
Amgen, Prof Mark Brown
Renal Supportive Care: Patient Outcomes and Quality of
Life, $74,678, 2012
Amgen Research Grant, A/Prof Ivor Katz
The development of a web-based Chronic Kidney Disease
Outreach Program, $ 60,000, 2012-2013.
Research Projects in Progress
Hypertension in chronic kidney disease (CKD)
Dr Sharon Ong and A/Prof John Kelly
1. Adequacy of blood pressure control in CKD
Dr Franziska Pettit MB BAO Bch BMSc MRCPI FRACP
2. 24 hour ambulatory and self home blood pressure
monitoring in CKD
Medical Students
3. Role of glucocorticoids in hypertension in CKD
Colin Chng
Foong Ming Ho
CKD health systems research
A/Prof Ivor Katz
Research Officers
1. 1Achievement of target BP & other risk factors on
CKD patients.
Saiyini Pirabhahar
Paula Williamson
Gemma Collett
2. Patterns of referral for CKD Management.
Nursing & Allied Health
Elizabeth Josland
Shelley Tranter
Tania Burns
Jennifer Beddoe
Yanella Matinez-Smith
Coralie Meek
Maria Chan
3. CKD to kidney failure - predictive model.
4. Web based CKD outreach program.
Hypertension in pregnancy
Prof Mark Brown and A/Prof George Mangos, A/Prof Greg
Davis and A/Prof Tony O’Sullivan)
1. The ‘new’ R-A-A system in pre-eclampsia.
2. Body composition in normal pregnancy.
Research Grants
3. Outcomes of hypertensive pregnancies.
Clive and Vera Ramaciotti Foundation Research
Establishment Grant, Dr Sharon Ong
4. Post-partum physiology, psychology and pediatric
outcomes for women with preeclampsia (the ‘P4’
study).
42
Renal palliative care
Dr Frank Brennan and Prof Mark Brown
1. The role of palliative care in improving quality of life
outcomes for hospital based haemodialysis patients.
2. Quality of life & symptom burden in dialysis patients.
3. Survival and symptom control of patients in Predialysis & Renal Supportive Care clinics.Outcomes
of patients in Pre-dialysis & Renal Supportive Care
clinics.
4. Retrospective and prospective studies of the effects
of a Renal Palliative care service on patients with CKD
stage 4/5 and their carers.
5. A study of ‘good deaths’ in dialysis patients.
Nutrition in CKD
Maria Chan and A/Prof John Kelly
1. Relationship between nutritional status and outcome
in end stage kidney disease.
Original Peer-Reviewed Publications
2012
Brown MA. Proteinuria in pre-eclamptic pregnancy: does it
matter anymore? Nat. Rev Nephrol. 2012; 8:563–565.
Brown MA, Roberts LM, Mackenzie C, Mangos G, Davis
GK. A Prospective Randomized study of Automated
versus mercury blood pressure recordings in hypertensive
pregnancy (PRAM study). Hypertension in Pregnancy.
2012;31:107-119.
Chan, M., J. Kelly, M. Batterham and L. Tapsell.
“Malnutrition (Subjective Global assessment) Scores and
Serum Albumin Levels, but not Body Mass Index Values,
at Initiation of Dialysis are Independent Predictors of
Mortality: A 10-Year Clinical Cohort Study.” Journal of
Renal Nutrition 22(6): 547-557, 2012.
Chan M. Nutrition, diabetes and chronic kidney disease,
Australian Diabetes Educator. Volume 15 Number 3,
August 2012, pp17-23.
Hawkins L-A, Brown MA, Mangos G, Davis GK. Transient
gestational hypertension: not always a benign event.
Pregnancy Hypertension. 2012; 2: 22-27.
Hawkins TL, Roberts JM, Mangos GJ, Davis GK, Roberts
L, Brown MA. Plasma Uric acid remains a marker of poor
outcome in hypertensive pregnancy: a retrospective cohort
analysis. British Journal of Obstetrics and Gynaecology
2012; 119:484–492.
Head GA, McGrath BP, Mihailidou AS, Nelson MR,
Schlaich MP, Stowasser M, Mangoni AA, Cowley D,
Brown MA, Ruta LA, Wilson J. Ambulatory blood
pressure monitoring in Australia: 2011 consensus position
statement. Journal of Hypertension 2012, 30:253–266.
Josland E, Brennan F, Anastasiou A, Brown MA.
Developing and sustaining a renal supportive care service
for people with end stage kidney disease. Renal Society of
Australasia Journal 2012; 8(1): 12-18.
Mangos GJ, Spaan J, Pirabhahar S, Brown MA. Markers of
cardiovascular disease risk after hypertension in pregnancy.
Journal of Hypertension 2012, 30:351–358.
Moustakas J, Bennett P, Tranter S, Nicholson J. The needs
of older people with advanced chronic kidney disease
choosing supportive care: a review. Renal Society of
Australasia Journal 2012, 8(2) 70-75.
Ong SLH, Whitworth JA. Glucocorticoid-induced
hypertension and the nitric oxide system. Expert Rev
Endocrinol Metab 2012; 7(3): 273-280.
Pettit F, Brown MA. The Management of Pre-eclampsia:
what we think we know. European Journal of Obstetrics &
Gynecology and Reproductive Biology 2012; 160: 6–12.
Pianta TJ, Horvath AR, Ellis VM, Leonetti R, Moffat C,
Josland EA, Brown MA.Cardiac high-sensitivity Troponin
T measurement: a layer of complexity in managing
hemodialysis patients. Nephrology. 2012; 17: 636–641.
Spaan J, Brown MA. Renin Angiotensin system in preeclampsia: everything old is new again. Obstetric
Med.2012;5: 147-153.
Spaan J, Peeters L, Spaanderman M, Brown MA.
Cardiovascular risk management after a hypertensive
disorder of pregnancy. Hypertension 2012;60:1368-1373.
Westgarth F, Chiarella M. & Tranter S. The Haemodialysis
Models of Care Program. Renal Society of Australasia
Journal 2012, 8(1) 24-31.
43
2013
Brennan FP. “Clock without Hands”. American Journal of
Hospice and Palliative Medicine 2013; 30(3):312-316.
Brennan FP. Conscientious Objector – Edna St Vincent
Millay, mortality and the nature of Palliative Care. Journal
of Palliative Care 2013; 29(2): 123-125.
Brennan FP, Brown M. An ethical approach to dialysis – an
alliance of Nephrology, Palliative Medicine and ethics.
Quarterly Journal of Medicine 2013; 106(5): 397-400.
Brennan FP. The New World of Ourselves. Journal of
Palliative Care 2013; 29(4): 258-259.
Brennan FP. Ethical Principles for Patients, Families and
Doctors to Consider. Nephrology 2013; 18: 413-414.
Brennan FP, Siva B, Crail S. Appropriate Assessment of
Symptom Burden and Provision of Patient Information.
Nephrology 2013; 18: 418-421.
Brennan FP. Holistic Palliative Care Approach - Physical,
Spiritual, Religious and Psychological Needs. Nephrology
2013;18: 421-423.
Brennan FP, Murrell DF. Report from the Inaugural
Australian Pruritus Symposium, Sydney, Australia, August
10 2013. Acta Derm Venereol 2013. Oct 24 (Epub ahead
of print).
Brown MA. Is there a role for ABPM in Pregnancy? Clinical
and Experimental Physiology and Pharmacology. 2013.
DOI.10.1111/1440-1681.12106.
Brown MA, Crail SM, Masterson R, Foote C, Robins J, Katz
I, et al. ANZSN Renal Supportive Care Guidelines 2013.
Nephrology. 2013;18(6):401-54.
Burns, T. Waiting for a kidney transplant in Australia.
Transplant Journal of Australasia, 2013b: 23, 10-15.
Crail S, Walker R, Brown M. Renal Supportive Care
working group. Renal supportive and palliative care:
position statement. Nephrology. 2013; 18(6):393-400.
Cuesta, C., Blow, T. & Tranter, S. Epidermolysis bullosa:a
rare challenge for peritoneal dialysis nurses. Renal Society
of Australasia Journal, 2013:9, 41-44.
Foo JY, Mangos GJ, Brown MA. Characteristics
of hypertensive disorders in twin versus singleton
pregnancies. Pregnancy Hypertension: An International
Journal of Women’s Cardiovascular Health 2013; 3:3-9.
Johnson DW, Atai E, Chan M, Phoon RKS, Scott C,
Tussaint N, Turner GI, Usherwood T, and Wiggins, K. KHACARI guideline: Early chronic kidney disease: detection,
prevention and management. Nephrology 18 (2013)
340–350.
44
Josland, E. Quality of Life. What information is already
available and what evidence is this based on? Nephrology,
2013c: 18, 410-413.
Lim CED, Siow S, Ho KEH, Chua JL, Chong N, Cheng L,
Kwok, Brennan FP, Cigolini M. Advance Care planning in
haemodialysis patients. Protocol Information. Cochrane
Reviews. Review number 294. September 2013.
Ong SLH, Vohra H, Zhang Y, Whitworth JA. The role
of mitochondrial superoxide in glucocorticoid-induced
hypertension. Oxid Med Cell Longev 2013; 2013:517045.
Pettit F & Ong SLH. Management of Hypertension in
Pregnancy. eMIMS Disease Index. Revision August 2013.
Prabhu A, Taylor P, Konecny P, Brown MA. Pyelonephritis:
What are the present day causative organisms and
antibiotic susceptibilities? Nephrology. 2013;18(6):463-7.
Siva B, Brennan FP. Inappropriate Interventions in the
Dying Patient. Nephrology 2013; 18: 423-424.
Spaan J, Bowyer L, Lazzaro V, McCrohon J, Brown MA.
Maternal hemodynamics influence fetal hemodynamics
in normal and hypertensive pregnancy. Pregnancy
Hypertension: An International Journal of Women’s
Cardiovascular Health. 2013; 3:10–15.
Spaan J, Brown MA. Can we protect the kidneys after
hypertensive pregnancy? Canadian Medical Association
Journal. 2013; 185:199-200.
Stewart C, Brennan FP. Legal Issues Concerning
Withholding and Withdrawal of Dialysis. Nephrology 2013;
18: 444-449.
Tranquilli AL, Brown MA, Zeeman GG, Dekker G, Sibai BM.
The definition of severe and early-onset pre-eclampsia.
Statements from the International Society for the Study
of Hypertension in Pregnancy (ISSHP). Pregnancy
Hypertension: An International Journal of Women’s
Cardiovascular Health. 2013; 3: 44–47.
Tranter S., Anastasiou A., Bazzi H., Burgess H. & Josland
E. The renal memorial service: an important component of
renal supportive care. Renal Society of Australasia Journal,
2013:9, 80-84.
Urban K, Brennan FP. Patients who withdraw from dialysis
in a Sydney centre with palliative care support: who, why,
and how they die. Progress in Palliative Care. Available
on-line February 1 2013.
Other Published Material
2012
Eastabrook G, Brown MA, Sargent I. The Origins and EndOrgan Consequences of Pre-eclampsia In: Von Dadelzen P,
Magee L (eds): Best Practice & Research Clinical Obstetrics
& Gynaecology: Hypertension in Pregnancy (Issue 25.4).
2011: 435 – 447.
Myint TM, Brown M, Fischer E. Pregnancy and dialysis. In:
Harris D, Elder G, Kairaitis L, Rangan G. (editors) Clinical
Dialysis. 2nd edition. McGraw Hill. Sydney. Australia.
2012: 90-96.
2013
Burns, T. Book review: “Nutritional Management of Renal
Disease”. Renal Society of Australasia Journal, 2013: 9,
143.
Chan M and Chadban S. Chapter 34: Nutritional
management of renal transplantation. Kopple J,
Massry S and Kalantar-Zadeh K. Textbook of Nutritional
Management of Renal Disease. Third Edition. Elsevier
Publishing, 2013.
Chan, M and Trevino-Becerra, A. Nutrition, exercise and
hemodialysis. Trevino-Becerra, A. (editor) Hemodialysis
Esquematica. Publisher, Prado (Mexico) and translated
into Spanish, 2013
Field, D. 2013. Book review: Understanding chronic kidney
disease a guide for non-specialists. Renal Society of
Australasia Journal, 9, 45.
Josland, E. Book review “Kidney disease: From advanced
disease to bereavement” Second edition. The Renal
Society of Australasia Journal, 2013: 9, 142.
Nutrition and Metabolism in Renal Disease (ICNMRD)
Honolulu, Hawaii. June.
Foo JY, Mangos G, Brown MA. Characteristics of
hypertensive disorders in twin versus singleton
pregnancies. Oral presentation at the XVIII ISSHP World
Congress July 9th – 12th, Geneva. Switzerland.
Josland E, Collett G, Brennan F, Brown MA. HOPE:
Helping Older People with End stage kidney disease.
Poster presentation at the BMJ International Forum
on Quality and Safety in Healthcare 2012 Le Palais des
Congrès, Paris, France; April.
Mangos GJ, Ram J, Brown M. The effect of cuff size
on automated blood pressure measurement. Poster
presentation at the International Society of Hypertension
Scientific Meeting, Sydney, September.
Ong SLH, Williamson PM, Pirabhahar S, Beddoe J,
Trajkovska B, Kelly JJ. Adequacy of blood pressure
control in chronic kidney disease. Oral presentation at the
International Society of Hypertension Scientific Meeting,
Sydney, September.
Ong SLH, Pirabhahar S, Trajkovska B, Cohen S, Williamson
PM, Youssef G, Kelly JJ. Blood pressure, fluid volume,
vascular and ventricular function in chronic kidney disease.
Poster presentation at the International Society of
Hypertension Scientific Meeting, Sydney, September.
Williamson PM, Campbell J, Whitworth JA, Kelly JJ.
The Effect of sustained release isosorbide mononitrate
(Imdur) on cortisol-induced hypertension in healthy human
subjects. Poster presentation at the International Society
of Hypertension Scientific Meeting, Sydney, September.
2012 National
Presentations at Scientific Meetings and
Conferences
Burns T. “Waiting for a kidney transplant in Australia –
latest trends”. Oral presentation at the Transplant Nurses
Association National Conference. Melbourne, November.
2012 International
Collett G. Renal Supportive Care: Holistic care for
advanced CKD patients and their families. NSW Palliative
Care Conference, Dubbo, October.
Brown M, Roberts L, Davis G, Mangos G. The UM-101
Mercury-free sphygmomanometer: a replacement for
mercury sphygmomanometry at last? Poster presentation
at the XVIII ISSHP World Congress. July 9th – 12th,
Geneva. Switzerland.
Chan M et.al. Nutritional characteristics and dietary
intake of patients attending the pre-dialysis assessment
clinic. Proceedings of the 16th International Congress
of Nutrition and Metabolism in Renal Disease (ICNMRD)
Honolulu, Hawaii, June.
Chan M et.al. Self-reported appetite and intake adequacy
In patients with non-dialysis chronic kidney disease.
Proceedings of the 16th International Congress of
Cuesta C, Robinson F, Blow, T & Mangos GJ Caring for
a peritoneal dialysis patient with Epidermyolosis Bullosa.
Oral presentation at the RSA conference, Melbourne.
Josland E, Collett G, Foote C, Tranter S, Brennan F &
Brown MA. Renal supportive care: holistic care for end
stage kidney disease patients and their families. Paper
presented at the 40th Renal Society of Australasia Annual
Conference, Melbourne.
Josland E. Hepatitis Protocol: Opening a can of worms.
Oral presentation at the RSA conference, Melbourne.
June.
45
Pirabhahar S, Robins J and Katz I. Assessment of
Nephrologists’ Referrals: Preventing Burnout. Poster
Presentation at the 48th Australian and New Zealand
Society of Nephrology, Auckland, New Zealand, August.
Moustakas J, Bennett P, Tranter S & Nicholson J.
Supportive care: what does the ‘patient” want? Paper
presented at the 40th Renal Society of Australasia Annual
Conference, Melbourne, June.
2013 International
Brown MA. Collett G, Josland EA, Brennan F. Non-dialysis
management in the elderly: survival, symptom control and
quality of life. American Society of Nephrology Kidney
Week. Atlanta. USA. November.
2013 - National
Chan, M, Tranter, S, Josland, E, Collett, G & Kelly J. 2013.
Association of nurtritional status and the future choice of
dialysis option in patients attending the multidisciplinary
predialysis assessment clinic Top 10 poster presentation at
the Renal Society of Australasia Conference Hobart. June.
Chan M, Kelly J, Batterham M and Tapsell L. Nutritional
characteristics and dietary intake of patients at enrolment
to the pre-dialysis assessment clinic. Dietitians Association
of Australia 30th National Conference, Canberra, May.
Chan M, Kelly J, Batterham M and Tapsell L. Self-reported
appetite and adequacy of energy and protein intakes in
patients with non-dialysis chronic kidney disease, Dietitians
Association of Australia 30th National Conference,
Canberra, May 2013.
Chan M, Kelly J, Batterham M and Tapsell L. Nutritional
status is associated with the future treatment choice - renal
replacement therapy vs. conservative care in end stage
kidney disease patients attending the multidisciplinary
pre-dialysis assessment clinic. 49th Australian and New
Zealand Society of Nephrology (ANZSN) Annual Scientific
Meeting, September.
Cuesta, A, Tranter, S & Blow T. Taking control: addressing
peritoneal dialysis related infection outcomes. Renal
society of australasia Conference Hobart. June..
Pettit F, Davis G, Henry A, Mangos G, Brown MA. Is early
onset pre-eclampsia worse for mother or baby? Society
of Obstetric Medicine Australia and New Zealand. Annual
46
Scientific Meeting. Fremantle, WA. October.
Tranter, S, Chan,M, Josland, E, Kerr E, McTaggart, S,
Collett, G & Tapsell L. Nutritional profileof patients at
enrolment to the multidisciplinary predialysis clinc 20022012. Top 10 poster presentation at the Renal society of
australasia Conference, Hobart. June.
Community Engagement
A/Prof Ivor Katz is involved in the The development of a
web-based Chronic Kidney Disease Outreach Program:
improving clinical outcomes of CKD patients in the St
George and Sutherland area.
>
Respiratory Medicine/Sleep Disorders
St George Hospital
Head of Department
Steven Lindstrom: MBBS (Hons) FRACP Conjoint lecturer
UNSW
Senior Medical
Elizabeth Clark: MFRCP, MBBS (Hons)
Andrew Ng: MBBS, FRCP
Con Archis: MBBS (Hons)
John Moses: MBBS, FRACP
Veronica Yozghatlian: MBBS, FRACP
Frank Yan: BSc (Med) MBBS, FRACP
Alexandra Smith: MBBS
Junior Medical
Saidul Ansary: MBBS
Ajantha Ragapuran: MBBS
Chin Goh: MBBS
Alpanamarissa Antony: MBBS, MRCP
Charles Prabhakar: BSC (Hons) MBBS
Michael Ssentamu: MBChB; MRCP (UK)
Research Staff
Linda O’Malley: RN, CM
Carol Gano: MND, BSc
Jay Flack: BSC (2012; 2013)
Cynthia Higgins: BSC (Nursing) (2012; 2013)
Research Projects in Progress
Industry Supported
A Phase 3, double-blind, multi-centre, randomized,
placebo-controlled trial evaluating repeated courses of
Aztreonam for Inhalation solution in subjects with non-CF
bronchiectasis and Gram-negative endobronchial infection
(Gilead AIR-BX1 Principal Investigator Steven Lindstrom.
A Phase 3, multi-centre, randomized, parallel group
controlled, double-blind study to investigate the safety
of inhaled Mannitol over 12 months for the treatment of
Bronchiectasis (DPM-B-305) Principal Investigator Steven
Lindstrom.
A multi-centre, randomized, double blind, placebocontrolled, parallel group, single season study to assess
the efficacy and safety of HI-1640V, an enteric coated oral
Vaccine tablet containing 45 mg H1-164 active substance
(inactivated, whole cells of non-typeable Haemophillus
influenza, isolate 164) for reducing the rate and severity
of acute exacerbations in patients with moderate to
severe chronic pulmonary disease. (H1-H005) Principal
Investigator, Elizabeth Clark.
A Phase 3, randomized, double-blind, placebo-controlled
study evaluating the efficacy, safety and tolerability of
two fixed dose combinations of Aclidinium Bromide/
Formoterol Fumerate compared to Aclidium Bromide/
Formeterol and placebo for 24 weeks treatment in patients
with moderate to severe stable chronic obstructive
pulmonary disease. (LAC-MD-31) Principal Investigator,
Steven Lindstrom.
A randomized, double-blind 12 week treatment, parallel
group study to evaluate efficacy and safety of QMF149
(150mcg/160 mcg o.d.) compared to salmeterol xinafoate/
fluticasone proprionate (50mcg/500 mcg b.i.d.) in patients
with chronic obstructive disease (QMF149F2202) Principal
Investigator Steven Lindstrom.
A randomized, double-blind placebo controlled study
to compare the efficacy of indacaterol with that of
placebo in patients with COPD who have not previously
received maintenance COPD medication, using blinded
tiotropium as active control. (QAB2425, INITIATE) Principal
Investigator Steven Lindstrom.
A Phase 3, double-blind, multi-centre, randomized,
placebo-controlled trial evaluating repeated courses of
Aztreonam for Inhalation solution in subjects with non-CF
bronchiectasis and Gram-negative endobronchial infection
(Gilead AIR-BX2) Principal Investigator, Steven Lindstrom.
Randomized, double-blind, placebo controlled, multicentre study comparing Ciprofloxacin DPI 32.5 mg BID
intermittently administered for 28 days on/28 days off
or 14 days on/14 days off versus placebo to evaluate
the time to first pulmonary exacerbation and frequency
of exacerbations in subjects with non-cystic fibrosis
bronchiectasis (RESPIRE) Principal Investigator Steven
Lindstrom (temporary PI during LSL taken by Dr Lindstrom
was Veronica Yozghatlian.
Investigator initiated
Cardiopulmonary exercise testing and quality life
assessments in patients with lung cancer undergoing
radiotherapy for curative intent. Principal Investigators:
Dr Alpanamarissa Antony, Dr Steven Lindstrom, Dr Yiauw
47
Chin, A/Prof Peter Graham.
Management of Pulmonary Embolism in a Hospital in the
Home Setting: St George Hospital Experience Principal
Investigator: Dr Alpanamarissa Antony supervised by Dr
Steven Lindstrom.
Procalcitonin use in the management of Community
Acquired Pneumonia – a randomised trial Principal
Investigator: Dr Chin Goh, supervised by Dr Steven
Lindstrom.
“Prevalence of sleep disordered breathing in an
orthodontic population” ‘The Sleepy Teeth Study’ Principal
Investigators: Dr Andrew Ng, Dr Chin Goh.
Presentations at Scientific Meetings and
Conferences
2013 - National
Dr Alpanamarissa Antony, Management of Pulmonary
Embolism in a hospital in the home setting: St George
Experience,: Royal Australasian College of Physicians
(RACP) Congress, Perth, May.
Dr Alpanamarissa Antony, Management of Pulmonary
Embolism in a hospital in the home setting: St George
Experience,: St George Hospital Symposium, Sydney.
Dr Alpanamarissa Antony, Management of Pulmonary
Embolism in a hospital in the home setting: St George
Experience NSW Thoracic Society of Australia and New
Zealand TSANZ NSW Branch Meeting, Sydney, November
(recipient of the Tracey Robinson Award for the best oral
presentation).
Community Engagement
Guidelines for the management of community acquired
pneumonia, 2013 Dr Steven Lindstrom Video link to
rural areas in NSW (supported by Agency of Clinical
Innovation).
48
>
Department of Rheumatology
St George Hospital
Head of Department
A/Prof Allan Sturgess MB BS (UQld), PhD (UMelb), FRACP,
FRCPA
Senior Staff Specialist, Conjoint A/Prof Medicine UNSW
Senior Medical
Prof Marissa Lassere MB BS (USyd), PhD (UNSW), Grad Dip
Epi (Newcastle), FRACP, FAFPHM. Senior Staff Specialist,
Conjoint Prof. Medicine UNSW
Dr Bill Giannakopoulos BSci (Med), MB BS (UNSW), PhD
(UNSW), FRACP
Senior Lecturer in Medicine UNSW, Consultant
Rheumatologist St George Hospital
Dr Ian Portek MB BS (USyd), FRACP
VMO Rheumatology, St George Hospital
Dr Lou McGuigan MB BS (UNSW), MD (UNSW), FRACP
VMO Rheumatology, St George Hospital
Junior Medical
Dr Jeff Tsai, Advanced Trainee Rheumatology, 2012
Dr Aishwarya Sukhedo, Advanced Trainee Rheumatology,
2013
Senior Research
Dr Kent Johnson BA (Harvard), BA (Oxford), MD (Johns
Hopkins)
Research Staff
Sue Baker BAppSc (Biomed) (UTS)
Tanya Thompson BSc (UNSW)
Research Allied Health
Guni Hinchey Grad Dip Sports (Germ.), Grad Dip Physio
Cathy Brand (B Sci Anatomy), Postgrad Dip Physio
Wendy Uptin BPhysio
Research Grants
NHMRC Project Grant 455467 Lassere MN, Sara T,
Johnson K, Iedema R, Rubin G. Electronic portable health
file (PHF) to promote quality of care and workflow through
continuity of care. 2007-2012 $665,500 CIA
evidence for surrogate therapeutics2008-2012 $510,00
CIA .
UNSW GOLDSTAR Principal investigators. Marissa Lassere,
Kent Johnson, Kerrie Mengersen, Mike Bradburn
Clinical and statistical heterogeneity in meta-analysis,
$40,000; 2012.
UNSW GOLDSTAR, Principal investigators. Marissa
Lassere, Kent Johnson, Jessie Berlin. Intelligent MetaAnalysis Models: Dealing With Heterogeneity, $40,000;
2013.
Research Projects in Progress
Long term outcome in patients with rheumatoid arthritis.
Lassere M, Edmonds J Portek I, Sturgess A, Baker S.
Health-related quality of life in patients on biologic
treatment for rheumatoid arthritis, psoriatic arthritis and
ankylosing spondylitis. Buchbinder R, Reid C, Lassere M,
March L.
Prevalence and predictors of all-cause hospitalization in
patients on biologic treatment for rheumatoid arthritis,
psoriatic arthritis and ankylosing spondylitis. Williams B,
Lassere M, March L, Buchbinder R, Reid C.
Incidence and predictors of tuberculosis and other serious
infections in patients on biologic treatment for rheumatoid
arthritis, psoriatic arthritis and ankylosing spondylitis.
Carroll G, Buchbinder R, Lassere M, March L, Reid C.
Incidence and predictors of malignancy in patients on
biologic treatment for rheumatoid arthritis, psoriatic
arthritis and ankylosing spondylitis. Buchbinder R, Reid C,
Lassere M, March L.
Why patients on biologic treatment for rheumatoid
arthritis, psoriatic arthritis and ankylosing spondylitis switch
biologic agents. Williams M, Buchbinder R, Reid C, Lassere
M, March L, Staples M.
The reliability and validity of Power Doppler ultrasound in
patients with rheumatoid arthritis. Joshua F, Lassere M.
Development and evaluation of the Tolerability and Safety
Questionnaire (TASQ): a patient-self report instrument of
treatment related tolerability and safety for use in clinical
trials. Lassere M, Johnson K.
NHMRC Project Grant 510272 Lassere MN, Johnson KR,
Dunsmuir W, Galbraith S, Ward R, Hughes M. Levels of
49
50
Evaluation of a prognostic measure of rheumatoid
arthritis damage progression using MRI, arthroscopy and
synovial membrane analysis. Kirkham B, Lassere M, Bird P,
Edmonds, Portek I.
An evaluation of the business, architectural, and workflow
requirements of the patient held PHF and the healthcare provider electronic medical record to understand
the shared information resources required to support a
collaborative care model. Lassere M, Iedema R, Sara T.
A randomised controlled trial to demonstrate the
effectiveness, acceptability, and sustainability of a patientheld portable health file on improving patient outcomes.
Lassere M, Johnson K, Iedema R, Sara T, Rubin G, Baker S.
Investigate current statistical methods to advance
biomarker and surrogate endpoint evaluation using
simulated and real data sets that reflect limitations of
data and statistical assumptions. Lassere M, Dunsmuir W,
Galbraith S, Johnson K.
The surrogate threshold effect (STE) of C-reactive protein
onradiographic progression and functional disability in
rheumatoid arthritis. Johnson K, Lassere M.
Journal. 2013, 43 66-72
Poh M.Q.W., Lassere M., Bird P., Edmonds J. Reliability
and longitudinal validity of computer-assisted methods
for measuring joint damage progression in subjects with
rheumatoid arthritis. Journal of Rheumatology. 2013, 40:
23-29
Johnson K. Letter to the Editor regarding Marciniak:
Clinical Trial System is Broken, BMJ 347, 16 December
2013.
Lassere M.N., Johnson K.R., Schiff M., Rees D. Is blood
pressure reduction a valid surrogate endpoint for stroke
prevention? an analysis incorporating a systematic review
of randomised controlled trials, a by-trial weighted errorsin-variables regression, the surrogate threshold effect (STE)
and the biomarker-surrogacy (BioSurrogate) evaluation
schema (BSES). BMC Medical Research Methodology.
2012, Mar 12;12:27. doi: 10.1186/1471-2288-12-27
Presentations at Scientific Meetings and
Conferences
2012 - International
The surrogate threshold effect (STE) of HBA1c in patients
with diabetes on cardiovascular events. Johnson K, Lassere
M.
Marissa Lassere, Biomarkers and Surrogate Endpoints:
Food and Drug Administration, Washington DC, USA,
June .
The surrogate threshold effect (STE) of progressionfree survival for overall survival in metastatic renal cell
carcinoma. Lassere M, Johnson K, Liauw W.
Marissa Lassere, Biomarkers Therapeutics: Health
Technology Group, Exeter University, Exeter, England,
June.
An evaluation of meta-analysis in the presence of
heterogeneity performance (bias, accuracy and coverage)
with varying trial parameters (size, number, treatment
effect, and variability) using simulations. Johnson K,
Lassere M, Mengersen K, Berlin J.
Marissa Lassere, Biomarkers Review of Statistical Issues:
National Cancer Institute: Bethesda Maryland USA
November.
A randomised controlled trial of a treat to target strategy
versus usual care in patients with rheumatoid arthritis.
LassereMN, Johnson KR, Sturgess A, Portek I, Edmonds J,
Bird P, Carlton K.
Cytokines, chemokines and vascular mediators of disease
activity and damage in rheumatoid arthritis. Lassere MN,
Sturgess A, Baker S.
Meta-analysis of image-guided versus blind corticosteroid
injection s in patients with arthritis. Johnson K, Lassere M,
Tsai T, Buchbinder R.
Original Peer-Reviewed Publications
Lassere M.N, Rappo J., Portek I.J., Sturgess A., Edmonds
J.P. How many life years are lost in patients with
rheumatoid arthritis? Secular cause-specific and all-cause
mortality in rheumatoid arthritis, and their predictors in
a long-term Australian cohort study. Internal Medicine
2012 - National
Marissa Lassere Australian Rheumatology Database: What
we can learn from Biologics Registries. NSW Australian
Rheumatology Meeting, 21 March, Sydney.
Marissa Lassere, Electronic Health Records: 14thAustralian
Annual Health Congress Sydney. March.
2013- International
Marissa Lassere, Biomarkers Update on Statistical Issues:
National Cancer Institute: Bethesda, Maryland USA
November.
2013 - National
Marissa Lassere, Systematic review of surrogate endpoints:
University of NSW, Sydney, March.
Marissa Lassere, What’s new (or old) in the medical
management of osteoarthritis. St George Hospital Sydney
September.
51
CANCER
SERVICES
Haematology
>
53
Medical Oncology
>
61
Palliative Care
>
69
Radiation Oncology
>
79
>
Department of Haematology
Head of Department
Research Grants
Professor Beng Chong, MBBS, PhD, FRCP, FRACP, FRCPA
Professor, Department of Medicine (Conjoint) UNSW
Director Clinical Haematology
NHMRC Drug-induced immune thrombocytopenia BH
Chong, M Davenport, $491,706 Jan 2011-Dec 2013.
Senior Medical
Professor Szu-Hee Lee, MBBChir, PhD, FRCPE, FRCPath,
FRACP, FRCPA, Senior Staff Specialist, Conjoint Professor
UNSW
Staff Specialists
Dr Sundra Ramanathan, MBBS, FRACP, FRCPA
Dr Fernando Roncolato, B Med FRACP FRCPA
Dr Xavier Badoux, MBBS, FRACP, FRCPA
Dr Shir-jing Ho, MBBS, FRACP, FRCPA
Dr Amanda Hugman, MBBS, FRACP, FRCPA
Research Staff
Dr Christine Hicks. BSc, MSc, PhD. Conjoint lecturer
UNSW
Scientific Staff
Sudha Pillai, Haematology Laboratory Manager
Susan Smith Deputy Haematology Laboratory Manager
Senior Scientists
NHMRC Heparin-induced thrombocytopenia and
thrombosis: Better understanding of pathogenesis and
improving diagnosis and treatment. BH Chong, C Parish
$631,010 Jan 2012-Dec 2014.
NSW Cancer Institute of NSW X. Badoux, ALLG Project
Manager $287,000 2013-2015.
Ho S, Cook C, Straube B, Fernandez R, et al. (2013-14).
The Action Study: Strategies to reduce the VRE infection
(Transmission and Bacteraemia) rates in high risk patients
admitted to 4E/4N wards. SESLHD infection prevention
and control enhancement program $100,000.
Various Sponsor Companies as listed below in research
projects in progress - Principal investigators:. Professor
Beng Chong, Dr Sundra Ramanathan, Dr Fernando
Roncolato, Dr Xavier Badoux, Dr Shir-jing Ho, Dr Amanda
Hugman, $ 530,000 2012 , $ 565,000 2013.
Unrestricted grant from GSK International I. ITP Registry:
A Multi-centre, prospective disease registry for adults
diagnosed with primary immune thrombocytopenia
purpura (ITP) Asia-Pacific, Middle Eastern and S American
countries 2011-2021, BH Chong ~$500,000 for 2012 2013.
Rosalie Gemmell, Coagulation Laboratory
Peter Loizou, Blood Bank
Nella Mangos, Morphology:
Christine Wassell. Bone Marrow Transplant Laboratory
Clinical Trials Unit
Roslyn Ristuccia BSc DipCompSc MMedSc(Epi), Manager
Sarah Davidson RN
Lorraine King RN
Michael Szwajcer RN (CNS)
Chris Sargent RN (CNS)
Margaret Loizou BSc
Elena Mendoza-Simon BSc
Victoria Stevens BSc (Pharmacy) – Clinical Trials Pharmacist
53
Research Projects in Progress
Short Title
Trial - Title
Principal
Investigator
ARES
Anticoagulant Reversal and Events Study (ARES Collaborative)
ASPIRE
Aspirin to prevent recurrent venous thromboembolism. A multicentre, randomised, double-blind, placebo-controlled clinical trial
Beng Hock Chong
examining the efficacy and safety of low-dose aspirin after initial
oral anticoagulation to prevent recurrent venous thromboembolism.
CTBR-005 'HITS'
Heparin-induced thrombocytopenia (HIT): Characterization of the
pathogenic and non-pathogenic antibodies, and studies to improve
laboratory diagnosis and treatment.
Beng Hock Chong
AMPLIFY EXTENSION
A Safety And Efficacy Trial Evaluating the use of Apixaban for the
Extended Treatment of Deep Vein Thrombosis and Pulmonary
Embolism
Beng Hock Chong
AMPLIFY TREATMENT
A Safety and Efficacy Trial Evaluating the Use of Apixaban in the
Treatment of Symptomatic Deep Vein Thrombosis and Pulmonary
Embolism
Beng Hock Chong
COMFORT 1
A Randomized, Double-blind, Placebo-controlled Study of the JAK
Inhibitor INCB018424 Tablets Administered Orally to Subjects With
Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis or
Post-Essential Thrombocythemia Myelofibrosis
Beng Hock Chong
AMG 20080009 ITP BMT
A Prospective, Phase IV, Open-Label, Multi-Center Study Evaluating
Changes in Bone Marrow Morphology in Adult Subjects Receiving
Romiplostim for the Treatment of Thrombocytopenia Associated
with Immune (Idiopathic) Thrombocytopenia Purpura (ITP)
Beng Hock Chong
The edoxaban HOKUSAI
VTE Study
A Phase 3, Randomized, Double-Blind, Double-Dummy, ParallelGroup, Multi-Center, Multi-National Study for the Evaluation of
Efficacy and Safety of (LMW) Heparin/Edoxaban Versus (LMW)
Heparin/Warfarin In Subjects with Symptomatic Deep-Vein
Thrombosis and/or Pulmonary Embolism
Beng Hock Chong
The EINSTEIN VTE
treatment study (St
George Private Hospital)
Oral direct factor Xa inhibitor rivaroxaban in patients with acute
symptomatic deep-vein thrombosis or pulmonary embolism. The
Einstein VTE study
Beng Hock Chong
TT4-ITP01
Triple Therapy for Primary Immune Thrombocytopenia (ITP)
Beng Hock Chong
M07-001 PNH Registry
A global, observational, non-interventional study collecting
effectiveness, safety and quality of life data on patients with
Paroxysmal Nocturnal Haemoglobinuria (PNH) Disease.
Beng Hock Chong
Amgen MM Observational Study
An Observational Study of Neutropenia in Subjects Being Treated
for Relapsed or Relapsed/Refractory Multiple Myeloma
Beng Hock Chong
ITP Registry
A Multi-centre, prospective disease registry for adults diagnosed
with primary immune thrombocytopenia purpura (ITP) in
international countries.
Beng Hock Chong
TWISTER
Two Weeks of Low Molecular Weight Heparin for Distal Vein
Thrombosis (TWISTER)
Beng Hock Chong
Biomarkers of IVIG efficacy during treatment
of ITP
Use of biomarkers as evidence based measurements of efficacy of
IVIG treatment of Immune Thrombocytopenia Purpura ITP
Beng Hock Chong
54
Amanda Hugman
E5501 EISAI ITP
A Phase 3, Multicenter, Randomised, Double-Blind, PlaceboControlled Parallel-group Trial with an open-label Extension Phase
to evaluate the Efficacy and Safety of Oral E5501 plus Standard of
care for the Treatment of Thrombocytopenia in Adults with Chronic
Immune Thrombocytopenia (Idiopathic Thrombocytopenia purpura)
Beng Hock Chong
INCB 39110-230
An Open-Label, Multiple Simon 2-Stage Study of INCB039110
Administered Orally to Subjects With Primary Myelofibrosis (PMF),
Post Polycythemia Vera-Myelofibrosis (PPV-MF) or Post Essential
Thrombocythemia-Myelofibrosis (PET-MF)
Beng Hock Chong
TRC117146 GSK AML
TRC 117146 is a randomised, single blinded, placebo-controlled,
dose finding study to assess the PK interaction, safety and efficacy
of the oral thrombopoietin receptor agonist, eltrombopag,
administered to subjects with Acute Myelogenous Leukaemia (AML)
receiving induction chemotherapy.
Beng Hock Chong
ASSIST GP13-301
A Randomized, Controlled, Double-Blind Phase III trial to Compare
the Efficacy, Safety and Pharmacokinetics of GP2013 plus CVP
vs. MabThera plus CVP, Followed by GP2013 or MabThera
Maintenance Therapy in Patients with Previously Untreated,
Advanced Stage Follicular Lymphoma
Fernando Roncolato
LEAF
The Lymphoma Lifestyle, Environment And Family Study
Fernando Roncolato
ALLG Tissue Bank
AMP Leukaemia and Lymphoma Tissue Bank A joint research
initiative of ALLG and the Leukaemia Foundation
Shir-jing Ho
ALLG TIDEL II CML9
A Phase II study in adult patients with newly diagnosed chronicphase chronic myeloid leukaemia of initial intensified imatinib
therapy and sequential dose-escalation followed by treatment
with nilotinib in suboptimal responders to determine the rate and
duration of major molecular response
Shir-jing Ho
ALLG MDS3
A Phase I/II trial to determine safety & efficacy of combination
therapy with 5-azacitidine (Vidaza) and Thalidomide in patients with
Myelodysplastic Syndromes (MDS)
Shir-jing Ho
ALLG NHL21
Early Treatment Intensification With R-ICE Chemotherapy and
Autologous Stem Cell Transplantation for Patients with Poor
Prognosis Diffuse Large B-Cell Lymphoma as Identified by
Interim PET/CT Scan Performed After Four Cycles of R-CHOP-14
Chemotherapy
Shir-jing Ho
ALLG CLL5 OFOCIR
An Australasian, phase II, multicentre, randomised, dose
intensification study investigating oral fludarabine, oral
cyclophosphamide and i.v. rituximab (poFCivR) tolerance in
previously untreated elderly (= 65 years old) patients with chronic
lymphocytic leukaemia
Shir-jing Ho
MDS4
A randomised Phase II study comparing the efficacy of 5azacitidine
alone versus combination therapy with lenalidomide and
5azacitidine in patients with higher risk myelodysplastic syndromes
(MDS) and low marrow blast count acute myeloid leukaemia (AML)
Shir-jing Ho
ALLG CML10 RESIST
Response Post Tyrosine Kinase Inhibitor: Assessment of Sensitivity
and Therapeutic Response to Next-Line Therapy in CML: The
Australasian RESIST study
Shir-jing Ho
55
Peritonectomy-PCC
A Randomised Controlled Trial to Compare Administration of
Prothrombin Complex Concentrate with Standard Haemostasis
Management In Adult Patients Undergoing Peritoneal
Cytoreductive Surgery Requiring Massive Transfusion.
Shir-jing Ho
AYA Pattern of Care
Patterns and Experiences of Care in Adolescents and Young Adults
with Cancer
Shir-jing Ho
ENDEAVOR MM
A Randomized, Open-label, Phase 3 Study of Carfilzomib Plus
Dexamethasone vs Bortezomib Plus Dexamethasone in Patients
with Relapsed Multiple Myeloma Protocol Number 2011-003
Shir-jing Ho
The ACTION study
Strategies to reduce vre infection (transmission and bacteraemia)
rates in high risk patients admitted to 4E/4N wards.
Shir-jing Ho
BP22333 Stage 1
A two-stage phase 1b study to investigate the pharmacokinetics
in patients with follicular lymphoma (FL) as part of maintenance
treatment
Sundra Ramanathan
BP22333 Stage 2
A two-stage phase 1b study to investigate the pharmacokinetics
in patients with follicular lymphoma (FL) as part of maintenance
treatment
Sundra Ramanathan
CLL 11 BO21004
An open-label, multi-center, three arm randomized, phase III study
to compare the efficacy and safety of RO5072759+chlorambucil
(GClb), rituximab + Chlorambucil (RClb) or chlorambucil (Clb) alone
in previously untreated CLL patients with comorbidities.
Sundra Ramanathan
ALLG MM11
A phase 3, Multicentre, Randomized, Controlled study to determine
the efficacy and safety of Cyclophosphamide, Lenalidomide and
Dexamethasone (CRD) versus Melphalan (200mg/m2) followed by
stem cell transplant in newly diagnosed multiple Myeloma subjects.
Sundra Ramanathan
GAUDI BO21000
An open-label, multi-centre,randomised, phase Ib study to
investigate the safety and efficacy of RO5072759 given in
combination with CHOP, FC or Bendamustine chemotherapy in
patients with CD20+ B-cell follicular non-Hodgkin's lymphoma.
Sundra Ramanathan
REMARC NHL25
Double blind randomized phase iii study of lenalidomide
(revlimid®)maintenance vs. Placebo in responding elderly patients
with diffuse large b cell lymphoma and treated with r-chop in first
line
Sundra Ramanathan
B1771007 Mantle Cell
Lymphoma
A Randomized Phase 4 study Comparing Intravenous Temsirolimus
(TEMSR) Regimens in Subjects with Relapsed, Refractory Mantle
Cell Lymphoma
Sundra Ramanathan
ENESTxtnd:
CAMN107E2401
Extending molecular responses with Nilotinib in newly diagnosed
chronic myeloid leukemia (CML) patients in chronic phase
(ENESTxtnd)
Sundra Ramanathan
Psychosocial Outcomes
An RCT
Improving Psychological Outcomes for Haematological Cancer
patients: An RCT
Sundra Ramanathan
Aplastic Anaemia Registry
Aplastic Anaemia Registry (AA)
Sundra Ramanathan
ENDORSE
EvaluatiNg outcomes of newly-DiagnOsed AML patients at St
GeoRge Hospital, SydnEy, Australia.
Sundra Ramanathan
ALLG AML M16
Sorafenib in combination with intensive chemotherapy for
previously untreated adult FLT3-ITD positive AML: a phase 2
randomised double-blind placebo controlled multi-centre study
Sundra Ramanathan
ALLG AML M18 Registry
Australasian Leukaemia and Lymphoma Group Common Acute
Myeloid Leukaemia Registry
Sundra Ramanathan
56
High Dose Melphalan
High dose melphalan: A pilot study to evaluate pharmacokineticbased dose determination in patients with multiple myeloma.
Sundra Ramanathan
ALLG MM14
A prospective randomised Phase II study of single agent
pomalidomide maintenance versus combination pomalidomide and
low dose dexamethasone maintenance following induction with
the combination of pomalidomide and low dose dexamethasone in
patients with relapsed and refractory myeloma previously treated
with lenalidomide
Sundra Ramanathan
ALLG MM15
A randomized phase III study to compare Bortezomib, Melphalan,
Prednisone (VMP) with High Dose Melphalan followed by
Bortezomib, Lenalidomide, Dexamethasone (VRD) consolidation
and Lenalidomide maintenance in patients with newly diagnosed
multiple myeloma
Sundra Ramanathan
SAWYER BO25341
An Adaptive, comparative, randomised, parallel-group, multicenter, Phase 1b study of subcutaneous (SC) rituximab versus
intravenous (IV) rituximab both in combination with chemotherapy
(flurarabine and cyclophoshamide), in patients with previously
untreated CLL
Xavier Badoux
ARD12042
A Randomized Phase II, Open-Label study of the Efficacy and Safety
of Orally Administered SAR302503 in patients with polycythemia
vera (PV) or essential thrombocythemia (ET) who are resistant or
intolerant to hydroxyurea
Xavier Badoux
SAWYER BO25341
(Part 2)
An Adaptive, comparative, randomised, parallel-group, multicenter, Phase 1b study of subcutaneous (SC) rituximab versus
intravenous (IV) rituximab both in combination with chemotherapy
(flurarabine and cyclophoshamide), in patients with previously
untreated CLL
Xavier Badoux
Continuum
A Phase 3, Multicenter, Randomized, Doubleblind, PlaceboControlled, Parallel-Group Study Of The Efficacy And Safety Of
Lenalidomide (Revlimid®) As Maintenance Therapy For Patients
With B-Cell Chronic Lymphocytic Leukemia Following Second Line
Therapy
Xavier Badoux
Gilead CLL GSUS-312-0119
A Phase 3, Randomized, Controlled Study Evaluating the Efficacy
and Safety of GS-1101 (CAL-101) in Combination with Ofatumumab
for Previously Treated Chronic Lymphocytic Leukemia
Xavier Badoux
RESONATE PCYC-1115CA
A Randomized, Multicenter, Open-label, Phase 3 Study of the
Brutons Tyrosine Kinase Inhibitor PCI-32765 versus Chlorambucil
in Patients 65 Years or Older with Treatment naive Chronic
Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Xavier Badoux
RESONATE 1116 Ext >
65yo
An Open-label Extension Study in Patients 65 Years or Older
with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic
Lymphoma (SLL) Who Participated in Study PCYC-1115-CA (PCI32765 versus Chlorambucil)
Xavier Badoux
57
Original Peer-Reviewed Publications
2012
Badoux X, Keating M, Wen, S, Wierda W, O’Brien S, Faderl
S, Sargent R, Burger J, Ferrajoli A (2013; Epub 2012 Dec
26). Phase II Study of Lenalidomide and Rituximab As
Salvage Therapy for Patients With Relapsed or Refractory
Chronic Lymphocytic Leukemia. Journal of Clinical
Oncology, 31(5):584-91.
Hicks, C, Trickett, A, Kwan, YL, Ramanathan, S. The
use of adjusted ideal body weight for overweight
patients undergoing HPC mobilisation for autologous
transplantation. Annals of Hematology. 2012, Volume 91,
Issue 11, pp 1795-1801.
Chong BH. Drug-induced thrombocytopenia: MIBS trumps
LIBS. Blood. 2012; 119 (26): 6177-8. PMID: 22745292.
Zini G, d’Onofrio G, Briggs C, Erber W, Lee SH, NcFadden
S, Yutaka N, Jou JM, Vives-Corrons JL, Lesesve JF. ICSH
recommendations for identification and quantification of
schistocytes. Int J Lab Hematol. 2012. 34(2): 107-116.
2013
Lee SH, van der Weyden C, Mayson E, Desai S. Excessive
EDTA induces morphologic changes in bone marrow
smears that mimic specific features of dysplasia. Int J Lab
Hematol. 2013 Apr;35(2):163-9.
Choi P, Gordon J, Harvey M, Chong B. Report on the
Presentation and Outcome of ITP in Single Australian
Centre. Intern Med J. 2012; 42(7):841-5. PMID:22805691.
Porter JB, Elalfy MS, Taher AT, Aydinok Y, Chan LL, Lee SH,
Sutcharitchan P, Habr D, Martin N, El-Beshlawy A. Efficacy
and safety of deferasirox at low and high iron burdens:
results from the EPIC magnetic resonance imaging
substudy. Ann Hematol. 2013 Jan;92(2):211-9.
Khachigian LM, Cai H, Moloney FJ, Parish CR, Chong BH,
Stocker R, Barnetson RS, Halliday GM. Destroying c-Jun
Messenger: New Insights into Biological Mechanisms of
DNAzyme Function. Oncotarget. 2012; 3(6):594-5. PMID:
22805148.
Braidy N, Gai WP, Xu YH, Sachdev P, Guillemin GJ, Jiang
XM, Ballard JW, Horan MP, Fang ZM, Chong BH, Chan
DK. Uptake and mitochondrial dysfunction of alphasynuclein in human astrocytes, cortical neurons and
fibroblasts. Transl Neurodegener. 2013; 2(1): 20.
Sanchez-Guerrero E, Chen E, Kockx M, An SW, Chong BH,
Khachigian LM. IL-1beta Signals through the EGF Receptor
and Activates Egr-1 through MMP-ADAM. PLoS One.
2012; 7(7):e39811. Epub 2012 Jul 6. PMID: 22792188.
Perdomo J, Yan F, Chong BH. A megakaryocyte with no
platelets: anti-platelet antibodies, apoptosis and platelet
production. Platelets.2013;24(2):98-106.
Caii H, Santiago FS, Prado-Lourenco L, Wang B, Patrikakis
M, Davenport MP, Maghzal GI Stocker R, Parish CR, Chong
BH, Lieschke GJ, Wong TW, Chesterman CN, Francis . DJ,
Moloney FJ, Barnetson RS, Halliday GM, Khachigian LM.
DNAzyme Targeting c-jun Suppresses Skin Cancer Growth.
Sci Transl Med. 2012; 4(139):139-82. PMID: 22723462.
Coupland LA, Beng H. Chong, Christopher R. Parish.
Platelets and P-selectin control tumor metastasis in an
organ-specific manner and independently of NK cells.
Cancer Research. Published Online July 26, 2012; doi:
10.1158/0008-5472.CAN-11-4010
Gao RL, Chong BH. Research and development of the
effective components of panaxdiol saponin as new
Chinese patent medicine for treating hemocytopenia. Chin
J Integr Med. 2012; 18(12): 897-902.
Perdomo J, Jiang XM, Carter DR, Khachigian LM, Chong
BH. SUMOylation regulates the transcriptional repression
activity of FOG-2 and its association with GATA-4. PLoS
One. 2012;7(11):e50637.
Perdomo J, Yan F, Chong BH. A megakaryocyte with
no platelets: anti-platelet antibodies, apoptosis and
platelet production. Platelets. 2013; 24(2):98-106. PMID:
22742725.
58
Chong BH, Chong JJ. HIT: nucleic acid masquerading as
heparin. Blood. 2013; 122(2): 156-158.
Chong BH, Choi PY, Khachigian L, Perdomo J. Druginduced immune thrombocytopenia. Hematol Oncol Clin
North Am. 2013; 27(3):521-40.
Coupland LA, Chong BH, Parish CR. Beware of NK Cells in
Pre-clinical metastasis models. Clin Exp Metastasis. 2013;
30(7):945-7
Sanchez-Guerrero E, Jo SR, Chong BH, Khachigian LM.
EFGR and the complexity of receptor crosstalk in the
cardiovascular system Curr Mol Med. 2013; 13(1): 3-12.
Review.
Tsimberidou AM, Wierda WG, Wen S, Badoux XC, et al.
Phase I-II clinical trial of oxaliplatin, fludarabine, cytarabine,
and rituximab therapy in aggressive relapsed/refractory
chronic lymphocytic leukemia or Richter syndrome. Clin
Lymphoma Myeloma Leuk. 2013;13(5):568-74.
Strati P, Keating MJ, Wierda WG, Badoux XC et al.
Lenalidomide induces long-lasting responses in elderly
patients with chronic lymphocytic leukemia. Blood.
2013;122(5):734-7.
Badoux XC, Keating MJ, Wen S, et al. Phase II study of
lenalidomide and rituximab as salvage therapy for patients
with relapsed or refractory chronic lymphocytic leukemia.
J Clin Oncol. 2013;31(5):584-91.
National Blood Centre, Haematology seminar. “Making
platelets in a flask” Kuala Lumpur, Malaysia
Other Published Material
The International Society on Thrombosis and Haemostasis,
Liverpool, United Kingdom, June 27-30, 2012. 58th Annual
SSC Meeting, Platelet Immunology Subcommittee:
“Drug-induced immune thrombobocytopena: Animal
Model”; “ Effects of drug-induced antibody on
megakaryocytes.”
Hsu D, Lee SH. Digital Imaging in Hematology. In
Laboratory Hematology Practice. Eds Marchant KM, Davis
B. Wiley-Blackwell. 2012. pp707-718
Greinacher A, Warkentin TE, Chong, BH. Heparin-induced
Thrombocytopenia, In Platlelets (3rd Edition) Ed Michelson
AD, Academic Press New York. 2012.
Chong BH, van der Weyden, Carrie. Deep vein thrombosis
and pulmonary embolism, in: Disease Index (Fifth Edition)
Ed: Worth O, MIMS Australia, 2012 .
Chong BH, Magnani HN. Danaparoid in the treatment of
heparin-induced throbocytopenia, in: Heparin-induced
Thrombocytopenia, Eds: Warkentin T, Greinacher A. 5th
Edition. Marcel Dekker, New York 2012.
Presentations at Scientific Meetings and
Conferences
2012 - International
Professor Beng Hock Chong
ITP lecture series April 5-9, 2012.Apollo Hospital Group,
Chennai, India. 2012 April 5. “ITP Update.”
Chhatrapati Shahuji Maharaj Medical University (formerly
King George Medical) Locknow, India, 21012 April 6.
“Management of ITP: New agents. “
National Haematology Update IX conference, 2012,
organized by the All India Institute of Medical Sciences,
New Delhi, April 7. “Management of ITP: International
Guidelines – Consensus and Differences. “
Tata Medical Centre and University, Kolkata, India. 21012,
April 9. “HIT and HITT. “Diagnosis and Management of
ITP.”
Royal College of Pathologists of Australasia South-east
Asia Lecture series June 5-12, 2012.
Chapter of Haematologists, College of Physicians, “How
I treat ITP patients including the pregnant patient.”
Singapore
Academy of Medicine, College of Pathologists, Annual
Meeting 2012 (Keynote Address) K Pratap Memorial
Lecture.” New Dawn In Laboratory Medicine.” Malaysia
University Putra Malaysia Haematology seminar. “Updates
on laboratory tests for immune platelet disorders”,
“Platelet function abnormalities in Myeloproliferative
Neoplasm and their laboratory testing.” Malaysia
Invited speaker by Hong Kong Association of Blood
Transfusion and Haematology and by Queen Mary
Hospital, HK: 26 -30 november 2012. Titles: (1) ITP:
pathogenesis & treatment; (2) Heparin-induced
thrombocytopenia; (3). Molecular regulation of
thrombopoiesis; (4) Anti-platelet therapy: basics & recent
advances.
Prof Szu-Hee Lee
Invited Speaker, “Optimizing the Quality of Bone Marrow
Specimens and Reports”, International Society for
Laboratory Hematology 2012, Nice, France, May 2012.
Int.J.Lab.Hematol. 2012, 34 (Suppl. 1): 32-33).
2012 - National
Prof Beng Hock Chong
Invited Speaker: ITP symposium Haematology Further
Education Activity, ITP in Australia Perth Feb 17 and
Melbourne Feb 20.
Invited Speaker : Pathology Update, Royal College of
Pathologists of Australasia, Sydney March 9-11,2012
“Drug-induced immune thrombocytopenia: Pathogenesis,
diagnosis and treatment.”
2013 - International
Prof Beng Hock Chong
Taiwan Haematology Society Annual Meeting, Taipei, 13th
-14th April, 2013: “Clinical decision making in ITP: When
to treat and how to treat.”
10th Malaysian Society of Haematology Scientific
Meeting 26 to 28th April 2013, Penang Malaysia.
“Megakaryocytopoiesis and Haemostasis in Normal
subject”; “The therapeutic use of thrombopoietic agents
and clot promoting factors”
Hicks C., Goodman N., Gemmell R., Roncolato F.,
Ramanathan S. Platelet harvest, cryopreservation and
infusion; Re-expanding the resources of the BMT lab.
Exp Hem 41(8) S1. Abstract. International Society for
Experimental Haematology ISEH. Vienna 2013
59
2013 - National
Gemmell R, Cavanaugh L, Hicks C, Roncolato F, Chong,
B. Platelet Function Testing of cryopreserved platelets.
Abstract. HAA Haematology Society of Australia and New
Zealand, the Australian & New Zealand Society of Blood
Transfusion and the Australasian Society of Thrombosis
and Haemostasis, Broadbeach, Queensland, 20-23
October.
Chong, BH. Carl de Gruchy Memorial Lecture, Title:
Platelet: Small Cell Big Impact, St Vincent Hospital,
Melbourne. 16 September.
Community Engagement
Professor Beng Chong
Member of the Board of St George Medical Research
Foundation and Deputy Chair, Scientific Advisory
Committee, St George Medical Research Foundation.
Member, Medical and Dental Appointments Committee,
St George Hospital, Sydney
Member of Clinical Council, St George Hospital, Sydney
Council member, Asia-Pacific Society of Thrombosis and
Haemostasis
Vice-President, Australian Bid Committee, International
Society of Thrombosis and Haemostasis
Prof Szu-Hee Lee
Chair of the Science and Education Committee of the
International Society of Haematology, Asia-Pacific Division
(ISHAPD) since 1997
Vice-President of the International Council for
Standardization in Hematology (ICSH) since 2009
Co-Chief Editor of the International Journal of Laboratory
Hematology since 2010
Member, Editorial Board, Pathology
Member, International Advisory Panel, Malaysian Journal
of Pathology
Vice-Chair, International Council for Standardization in
Haematology.
60
>
Department of Medical Oncology
Head of Department
Research Grants
Dr Kiran Phadke MB CHB FRACPA FRACP
NSW Cancer Institute
Associate Professor Winston Liauw
Cancer Clinical Trials Staff Grant
$262,581 2012-2014.
Senior Medical
Dr Patricia Bastick MB BS BMedSc FRACP Grad Cert
Epidemiology, Conjoint Associate Lecturer UNSW
Dr Chee Lee MB BS MMEDSC (Clinical Epidemiology)
FRACP MBiostats PhD
Associate Professor Winston Liauw, MB BS MMedSC
FRACP GAICD Grad Cert Politics and Policy
Conjoint Associate Professor Matthew Links, MB BS
FRACP PhD
Dr Jodi Lynch, MB BS FRACP
Dr Katrin Sjoquist, MB BS BSc Med FRACP MClinT
Dr David Thomas, MB BS FRACP
Research Staff
Peter Fink BSc – Manager, Clinical Trials Unit
Clinical Trials Coordinators
Antoinette Fontela BSc
Mary Margaret Gozar PhD
Stephen Millard CNS
Indira Mismit RN
Shu Pan BSc
Penelope Taylor CNS
Lisa Wang MSc
Victoria Stevens BPharm – Clinical Trials Pharmacist
Cancer Australia
L.Mileshkin, M.Quinn, P.Khaw, C.Creutzberg, M.Stockler,
A. Brand, J. Martyn, K. Sjoquist
Randomised Phase III Trial Comparing Concurrent
Chemo- radiation and Adjuvant Chemotherapy with
Pelvic Radiation Alone in High Risk and Advanced Stage
Endometrial Carcinoma: PORTEC-3
$300,878 2012-2014.
University of Sydney Cancer Research Fund Grant (CRFG).
M.Friedlander, K Sjoquist
Intraperitoneal Bevacizumab Therapy in Malignant Ascites,
$50,000 2011-2012.
Ovarian Cancer Research Foundation (OCRF)
D Robertson, H Burger, M Friedlander, K Sjoquist, J
Martyn. The role of Inhibin as a biomarker of response in
Granulosa Cell Tumours
$20,000 2012-2014.
Cancer Australia Project Grant 626201
Principal investigators A/Prof P Graham, Prof G Delaney,
Dr E Millar, Dr Anne Capp, Als Prof R Sutherland, Dr S
Carroll, Dr J Harvey, Dr J Lynch, Dr R Tse. Trans Tasman
Radiation Oncology Group 08.06: A Randomised
comparison of anastrozole commenced before and
continued during adjuvant radiotherapy for breast cancer
versus anastrozole and subsequent anti-oestrogen
therapy delayed until after radiotherapy. (STARS – Study
of Anastrozole and Radiotherapy Sequencing). $660,000
2010-2012.
61
Research Projects in Progress
Short Name
Title
Principal
Investigator
COMPARZ
Study VEG108844, a Study of Pazopanib Versus Sunitinib in the
Treatment of Subjects With Locally Advanced and/or Metastatic
Renal Cell Carcinoma
BETH
A Multicenter Phase III Randomized Trial of Adjuvant Therapy
for Patients With HER2-Positive Node-Positive or High Risk
Node-Negative Breast Cancer Comparing Chemotherapy
Plus Trastuzumab With Chemotherapy Plus Trastuzumab Plus
Bevacizumab
BCIRG 006
Randomized phase III trial comparing doxorubicin and
cyclophosphamide followed by docetaxel (AC->T) with
doxorubicin and cyclophosphamide followed by docetaxel and
trastuzumab (AC->TH) and with docetaxel, platinum salt and
trastuzumab (TCH) in the adjuvant treatment of node positive
and high risk node negative patients with operable breast cancer
containing the HER2neu alteration.
Matthew Links
Carbo/Tax
CARBO/TAX: Wkly Carboplatin + Taxol and Concomitant RT for
locally advanced NSCLC: Predictors of Rx Tolerance.
Matthew Links
SOFT
A phase III trial evaluating the role of ovarian function
suppression and the role of exemestane as adjuvant therapies for
premenopausal women with endocrine responsive breast cancer.
Jodi Lynch
BCIRG 005
Randomized phase III trial comparing docetaxel in combination
with doxorubicin and cyclophosphamide (TAC) versus doxorubicin
and cyclophosphamide followed by docetaxel (AC->T) as adjuvant
treatment of operable breast cancer HER2neu negative patients
with positive axillary lymph nodes
Matthew Links
AG0102 GIST
Phase III randomised, multi-centre, international trial to determine
the relation between dose and clinical activity of STI-571 in
patients with unresectable or metastatic malignant gastrointestinal
stromal tumors expressing the c-kit receptor tyrosine kinase
(CD117).
Matthew Links
CO.20
A phase III randomised study of Brivanib (BMS-582664) in
combination with Cetuximab (Erbitux½) versus Placebo in
combination with Cetuximab (Erbitux½) in patient previously
treated with combination chemotherapy for metastatic colorectal
carcinoma
Winston Liauw
RAD001
A Phase 1 study of RAD001 (everolimus) in combination with
fluvastin and zoledronic acid in patients with solid tumours
Matthew Links
TEACH
A Randomized, Double-Blind, Multicenter, Placebo-Controlled
Study of Adjuvant Lapatinib (GW572016) in Women With EarlyStage ErbB2 Overexpressing Breast Cancer
Jodi Lynch
VEG102616
Phase II, multi-center, two-stage study utilising a randomised
discontinuation design to evaluate the safety and efficacy of
GW786034 in adult subjects with locally recurrent or metastatic
clear-cell Renal Cell Carcinoma (RCC).
Winston Liauw
62
Winston Liauw
Jodi Lynch
Inspire
A Randomized, Multicenter, Open-Label Phase 3 Study of
Pemetrexed-Cisplatin Chemotherapy Plus IMC-11F8 Versus
Pemetrexed-Cisplatin Chemotherapy Alone in the First-Line
Treatment of Patients With Nonsquamous Stage IIIb or IV NonSmall Cell Lung Cancer (NSCLC)
Matthew Links
Squire
A Randomized, Multicenter, Open-Label, Phase 3 Study of
Gemcitabine-Cisplatin Chemotherapy Plus Necitumumab (IMC11F8) Versus Gemcitabine-Cisplatin Chemotherapy Alone in the
First- Line Treatment of Patients With Stage IV Squamous NonSmall Cell Lung Cancer (NSCLC)
Matthew Links
D-Care
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center
Phase 3 Study of Denosumab as Adjuvant Treatment for Women
with Early-Stage Breast Cancer at High Risk of Recurrence
(D-CARE)
Jodi Lynch
CATS
Prediction of cardiotoxicity by measurement of serum N-terminal
pro-B-type natriuretic peptide in breast cancer patients receiving
adjuvant trastuzumab
Jodi Lynch
BCIRG 006 Sub study
Multicenter Phase III Randomized Trial Comparing Doxorubicin
And Cyclophosphamide Followed By Docetaxel (AC®T) With
Doxorubicin And Cyclophosphamide Followed By Docetaxel
And Trastuzumab (Herceptin®) (AC®TH) And With Docetaxel,
Carboplatin And Trastuzumab (TCH) In The Adjuvant Treatment
Of Node Positive And High Risk Node Negative Patients With
Operable Breast Cancer Containing The Her2 Alteration. Breast
Cancer Recurrence Substudy
Matthew Links
CA184095
Randomized, Double-Blind, Phase 3 Trial to Compare the
Efficacy of Ipilimumab vs Placebo in Asymptomatic or Minimally
Symptomatic Patients with Metastatic Chemotherapy-Naïve
Castration Resistant Prostate Cancer
Patricia Bastick
Rainbow
A Randomized, Multicenter, Double-Blind, Placebo-Controlled
Phase 3 Study of Weekly Paclitaxel With or Without Ramucirumab
(IMC-1121B) Drug Product in Patients With Metastatic Gastric
Adenocarcinoma, Refractory to or Progressive After First-Line
Therapy With Platinum and Fluoropyrimidine
Winston Liauw
BR.26
A Double Blind Placebo Controlled Randomized Trial Of PF-804 In
Patients with Incurable Stage IIIb/IV Non-Small Cell Lung Cancer
After Failure Of Standard Therapy For Advanced Or Metastatic
Disease
Matthew Links
Predict IR
The Utility Of Genomics And Functional Imaging To Predict
Irinotecan Pharmacokinetics And Pharmacodynamics: The Predict
IR Study
Winston Liauw
Marquee
A Phase 3, Randomized, Double-Blinded, Placebo-Controlled
Study Of ARQ 197 Plus Erlotinib Versus Placebo Plus Erlotinib In
Previously Treated Subjects With Locally Advanced Or Metastatic,
Non-Squamous, Non–Smallcell Lung Cancer (NSCLC)
Matthew Links
Bolero 3
A randomized Phase III, double-blind, placebo-controlled
multicenter trial of daily everolimus in combination with
trastuzumab and vinorelbine, in pretreated women with HER2/neu
over-expressing locally advanced or metastatic breast cancer
Patricia Bastick
63
Gamma
A Phase 3, multicenter, randomized, double-blind, placebo
controlled trial of AMG 479 or placebo in combination with
Gemcitabine as first-line therapy for metastatic adenocarcinoma of
the pancreas
Winston Liauw
TADE
A Multi-Centre Study of Tamoxifen Dose Escalation Study in Breast
Cancer Patients with CYP2D6 Polymorphisms
Jodi Lynch
Th3resa
A Phase III Randomized, Multicenter, Two-Arm, Open-Label Trial to
Evaluate the Efficacy of Trastuzumab Emtansine Compared With
Treatment of Physician's Choice in Patients With HER2 Positive
Metastatic Breast Cancer Who Have Received at Least Two Prior
Regimens of HER2 Directed Therapy
Patricia Bastick
Attache
A Trial in the Timing of Surgery and Adjuvant Chemotherapy for
Hepatic Metastases from Colorectal Cancer. A phase III, multi-centre, randomised trial comparing perioperative morbidity between
those given chemotherapy prior to and post surgical resection
versus those given chemotherapy post surgical resection.
Winston Liauw
Fergi
A Phase II, Double-Blind, Placebo Controlled, Randomized Study
of GDC-0941 or GDC-0980 With Fulvestrant Versus Fulvestrant
in Advanced or Metastatic Breast Cancer in Patients Resistant to
Aromatase Inhibitor Therapy
Jodi Lynch
SafeHer
A Phase III Prospective, Two-Cohort Non-Randomized, MultiCentre, Multinational, Open Label Study To Assess The Safety Of
Assisted- And Self-Administered Subcutaneous Trastuzumab As
Adjuvant Therapy In Patients With Operable Her2-Positive Early
Breast Cancer
Patricia Bastick
IDEate
Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing
the Efficacy of Ipilimumab Plus Etoposide/Platinum Versus
Etoposide/Platinum in Subjects With Newly Diagnosed ExtensiveStage Disease Small Cell Lung Cancer (ED-SCLC)
Chee Lee
Baton
A Phase 2, Open Label, Multicenter, Randomized Trial Comparing
Tivozanib in Combination With mFOLFOX6 to Bevacizumab in
Combination With mFOLFOX6, In Stage IV Metastatic Colorectal
Cancer (mCRC) Subjects
Winston Liauw
Lux Lung-7
A Randomised, Open-label Phase IIb Trial of Afatinib Versus
Gefitinib as First-line Treatment of Patients With EGFR Mutation
Positive Advanced Adenocarcinoma of the Lung
TOPS Trial
A controlled trial of an optimized multidisciplinary intervention for
post-cancer fatigue
Patricia Bastick
Integrate
A randomised phase II double-blind study to evaluate the effect of
Regorafenib or placebo on progression-free survival and objective
response rate in refractory advanced oesophago-gastric cancer
(AOGC)
Katrin Sjoquist
Affinity
A Randomized Phase 3 Study Comparing Cabazitaxel/Prednisone
in Combination With Custirsen (OGX-011) to Cabazitaxel/
Prednisone for Second-Line Chemotherapy in Men With Metastatic
Castrate Resistant Prostate Cancer.
Patricia Bastick
Mic-1
Phase II study investigating the ability of Macrophage Inhibitory
Cytokine-1 (MIC-1) and associated plasma markers to predict
response to chemotherapy in men with metastatic castrateresistant prostate cancer
Patricia Bastick
64
Chee Lee
Dareck
A Phase II, Multicenter, Open-Label, Randomized Study Evaluating
the Efficacy and Safety of MEHD7945A + FOLFIRI Versus
Cetuximab + FOLFIRI in Second Line in Patients With KRAS
Wildtype Metastatic Colorectal Cancer
Winston Liauw
M10-897
A Randomized, Double-Blind, Phase 2, Dose-Ranging Study to
Evaluate the Safety and Efficacy of Veliparib and Whole Brain
Radiation Therapy Versus Placebo and Whole Brain Radiation
Therapy in Subjects With Brain Metastases From Non-Small Cell
Lung Cancer.
Matthew Links
BEZ235
Randomized phase II study of BEZ235 or everolimus in advanced
pancreatic neuroendocrine tumours.
Winston Liauw
Enspirit
A Multinational, Randomized, Open-Label Phase III Study of
Custirsen (TV-1011/OGX-011) In Combination With Docetaxel
Versus Docetaxel As A Second-Line Treatment In Patients With
Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer
Everexes
A phase IIIb, multi-center, open-label, expanded access study of
EVERolimus (RAD001) in combination with EXemestane in postmenopausal women with EStrogen receptor positive, human
epidermal growth factor receptor 2 negative locally advanced or
metastatic breast cancer EVEREXES
Patricia Bastick
TACTIC
A randomised phase II study evaluating the potential molecular
profile of biliary tract cancer and also examining the clinical benefit
and safety of panitumumab, cisplatin and gemcitabine in the
treatment of biliary tract cancer.
Winston Liauw
CHALLENGE
A Phase III Study of the Impact of a Physical Activity Program on
Disease-Free Survival in Patients With High Risk Stage II or Stage
III Colon Cancer: A Randomized Controlled Trial
Winston Liauw
AMG386
A Phase 1b/2 Trial of AMG 386 in Combination With Pemetrexed
and Carboplatin as First Line Treatment of Metastatic NonSquamous Non-Small Cell Lung Cancer
Matthew Links
CO23
A Phase Iii Randomized Study of Bbi608 and Best Supportive
Care versus Placebo and Best Supportive Care In Patients with
Pretreated Advanced Colorectal Carcinoma
Winston Liauw
Aura
Safety, Tolerability, Pharmacokinetics & Antitumour Activity of
AZD9291 in Patients With Advanced Non Small Cell Lung Cancer
Who Have Progressed on Prior Therapy With an Epidermal Growth
Factor ReceptorTyrosine Kinase Inhibator Agent
Chee Lee
Chee Lee
65
Original Peer-Reviewed Publications
2012
Chua, T., Al-Alem, I., Zhao, J., Glenn, D., Liauw, W., &
Morris, D. (2012). Radiofrequency Ablation of Concomitant
and Recurrent Pulmonary Metastases after Surgery for
Colorectal Liver Metastases. Annals of Surgical Oncology,
19(1), 75-81.
Chua, T., Liauw, W., & Morris, D. (2012). Early recurrence
of pseudomyxoma peritonei following treatment failure
of cytoreductive surgery and perioperative intraperitoneal
chemotherapy is indicative of a poor survival outcome.
International Journal of Colorectal Disease, 27(3), 381-389.
Chua, T., Liauw, W., Zhao, J., & Morris, D. (2012).
Comparative analysis of perioperative intraperitoneal
chemotherapy regimen in appendiceal and colorectal
peritoneal carcinomatosis. International Journal of Clinical
Oncology, Jun;18(3):439-46.
Chua, T. C., Chong, C. H., Liauw, W., & Morris, D. L.
(2012). Approach to Rectal Cancer Surgery. International
Journal of Surgical Oncology, 2012 2012. Published on
line June 27 2012: Article ID 247107.
Chua, T. C., Chong, C. H., Liauw, W., Zhao, J., &
Morris, D. L. (2012). Inflammatory Markers in Blood and
Serum Tumor Markers Predict Survival in Patients With
Epithelial Appendiceal Neoplasms Undergoing Surgical
Cytoreduction and Intraperitoneal Chemotherapy. Annals
of Surgery, 256(2), 342-349.
Chua, T. C., Liauw, W., Chu, F., & Morris, D. (2012).
Viewing Metastatic Colorectal Cancer as a Curable Chronic
Disease. American Journal of Clinical Oncology, 35(1),
77–80.
Chua, T. C., Liauw, W., Chu, F., & Morris, D. L. (2012).
Summary outcomes of two-stage resection for advanced
colorectal liver metastases. Journal of Surgical Oncology,
2013 Feb;107(2):211-6.
Chua, T. C., Moran, B. J., Sugarbaker, P. H., Levine, E. A.,
Glehen, O., Gilly, F. N., Baratti, D., Deraco, M., Elias, D.,
Sardi, A., Liauw, W., Yan, T. D., Barrios, P., Gómez Portilla,
A., de Hingh, I. H. J. T., Ceelen, W. P., Pelz, J. O., Piso, P.,
González-Moreno, S., Van Der Speeten, K., & Morris, D.
L. (2012). Early- and Long-Term Outcome Data of Patients
With Pseudomyxoma Peritonei From Appendiceal Origin
Treated by a Strategy of Cytoreductive Surgery and
Hyperthermic Intraperitoneal Chemotherapy. Journal of
Clinical Oncology, 30(20), 2449-2456.
Chua, T. C., Saxena, A., Liauw, W., Chu, F., & Morris, D.
L. (2012). Hepatectomy and resection of concomitant
extrahepatic disease for colorectal liver metastases – A
systematic review. [doi: 10.1016/j.ejca.2011.10.034].
European Journal of Cancer (0).
66
Dimoska, A., Butow, P. N., Lynch, J., Hovey, E., Agar, M.,
Beale, P., & Tattersall, M. H. N. (2012). Implementing
patient question-prompt lists into routine cancer care.
[doi: 10.1016/j.pec.2011.04.020]. Patient Education and
Counseling, 86(2), 252-258.
C.K. Lee, C. Brown, R. Gralla, V. Hirsh, A. Inoue, V.
Gebski, C.J. Yang. Impact Of Epidermal Growth Factor
Receptor-Tyrosine Kinase Inhibitor Treatment In Advanced
Non-Small Cell Lung Cancer: A Meta-Analysis. Annals of
Oncology 2012, 23 (suppl 9): ix400-ix446.
Chee Khoon Lee, Ian Marschner, R John Simes, Merryn
Voysey, Brian Egleston, Gary Hudes, Paul de Souza.
Increase in cholesterol predicts survival advantage in renal
cell carcinoma patients treated with temsirolimus. Clinical
Cancer Research 2012, 18(11), 3188–3196.
C. K. Lee, R. J. Simes, C. Brown, V. Gebski, J Pfisterer,
A-M. Swart, D. Berton-Rigaud, M. Plante, T. Skeie-Jensen,
I. Vergote, C. Schauer, C. Pisano, G. Parma, K. Baumann,
J. A. Ledermann, E. Pujade-Lauraine, J. Bentley, G.
Kristensen, A. Belau, M. Nankivell, U. Canzler, S. J. Lord,
C. Kurzeder, M. Friedlander. A prognostic nomogram to
predict overall survival in patients with platinum-sensitive
recurrent ovarian cancer. Annals of Oncology 2012. 2013
Apr;24(4):937-43.
Links, M., Sargeant, C., Waters, A., Liauw, W., & Thomas,
P. (2012). Implementing a Multi-professional Web-based
Learning Environment for a Comprehensive Cancer
Centre: Obstacles, Solutions and Reflections. Journal of
Cancer Education, 27(1), 37-41.
Verry H, Lord SJ, A Martin A, Gill G, Lee CK, Howard K,
Wetzig N, Simes J. Effectiveness and cost-effectiveness
of sentinel node biopsy compared with axillary node
dissection in patients with early stage breast cancer: a
decision model analysis. British Journal of Cancer 2012,
106, 1045–1052.
Waller, A., Girgis, A., Johnson, C., Lecathelinais, C.,
Sibbritt, D., Forstner, D., Liauw, W., & Currow, D. C. (2012).
Improving Outcomes for People With Progressive Cancer:
Interrupted Time Series Trial of a Needs Assessment
Intervention. Journal of Pain and Symptom Management,
43(3), 569-581.
2013
Lobb, E. A., J. Lacey, J. Kearsley, W. Liauw, L. White
and A. Hosie (2013). Living with advanced cancer and
an uncertain disease trajectory: an emerging patient
population in palliative care? BMJ Supportive & Palliative
Care. 2013 Jan 29.
Sommeijer, D. W., K. M. Sjoquist and M. Friedlander
(2013). Hormonal Treatment in Recurrent and Metastatic
Gynaecological Cancers: A Review of the Current
Literature. Current Oncology Reports: 2013 Dec;15(6):5418.
Price TJ, Hardingham JE, Lee CK, Townsend AR, Wrin JW,
Wilson K, et al. Prognostic impact and the relevance of
PTEN copy number alterations in patients with advanced
colorectal cancer (CRC) receiving bevacizumab. Cancer
Medicine 2013, doi: 10.1002/cam4.75.
Lee CK, Brown C, Gralla RJ, Hirsh V, Thongprasert S, Tsai
C-M, Tan EH, Ho JC-M, Chu DT, Zaatar A et al. Impact
of EGFR Inhibitor in Non–Small Cell Lung Cancer on
Progression-Free and Overall Survival: A Meta-Analysis.
Journal of the National Cancer Institute 2013, 105(9):595605.
You B, Colomban O, Heywood M, Lee C, Davy M, Reed N,
Pignata S, Varsellona N, Emons G, Rehman K, Steffensen
KD, Reinthaller A, Pujade-Lauraine E, Oza A. The strong
prognostic value of KELIM, a model-based parameter from
CA 125 kinetics in ovarian cancer: Data from CALYPSO trial
(a GINECO-GCIG study). Gynecologic Oncology 2013,
doi:10.1016/j.ygyno.2013.05.013.
Peter Fox, Malcolm Hudson, Chris Brown, Sarah Lord,
Val Gebski, Paul De Souza, Chee Khoon Lee. Markers of
systemic inflammation predict survival in patients with
advanced renal cell cancer. British Journal of Cancer 2013,
109, 147–153.
Chee Khoon Lee, Val J Gebski, Alan S Coates, AnneSophie Veillard, Vernon Harvey, Martin HN Tattersall,
Michael J Byrne, Brian Brigham, John Forbes, R John
Simes and on behalf of Australia and New Zealand Breast
Cancer Trials Group (ANZBCTG). Trade-offs in quality
of life and survival with chemotherapy for advanced
breast cancer: mature results of a randomized trial
comparing single-agent mitoxantrone with combination
cyclophosphamide, methotrexate, 5-fluorouracil and
prednisone. SpringerPlus 2013, 2:391.
Felicia Roncolato, Pei Ding, Sally Lord, Val Gebski, Chee
Khoon Lee. Risk of Treatment-related Mortality with
Bevacizumab treatment in advanced cancers. European
Journal of Cancer 2013; 49, Supplement 2.
Pei Ni Ding, Richard Gralla, Akira Inoue, Sally Lord, Nick
Pavlakis, Tetsuya Mitsudomi, Matthew Links, Val Gebski,
James C. Yang, Chee Khoon Lee. Exon 19 deletions,
smoking history and gender as additional predictive
factors for treatment benefit with EGFR Tyrosine Kinase
Inhibitors in patients harbouring activating EGFR
mutations: A Meta-analysis of 1432 patients in six
randomised trials. Journal of Thoracic Oncology 2013; 8,
Supplement 2, S593.
Pei Ni Ding, Sally Lord, Matthew Links, Victoria Bray,
Val Gebski, James C. Yang, Chee Khoon Lee. Toxicity
of Epidermal Growth Factor Receptor Tyrosine Kinase
Inhibitors (EGFR-TKIs) in the Treatment of Advanced NonSmall Cell Lung Cancer (NSCLC): A Meta-analysis. Journal
of Thoracic Oncology 2013; 8, Supplement 2, S593,
Other Published Material
Chow, Hui Ting, Tran, Kim, Millar, Ewan K. A., Lynch,
Jodi, Murrell, Dedee F. (2012). Diverse Presentations of
Carcinoma Erysipelatoides from a Teaching Hospital in
Australia. Case Rep Dermatol Med. 2012; 2012: 134938.
Links, M., & Galettis, P. (2012). One Step Closer to the
Target: Intracellular Pharmacokinetics of Gemcitabine (20
April, 2012 ed.): InTech, April, 2012.
Presentations at Scientific Meetings and
Conferences
2012 International
YJ Chua, C Karapetis, C Underhill, L M.Nott, D Goldstein,
M Cronk, V Gebski, N Wong, K M Sjoquist, A Biankin,
Australasian Gastrointestinal Trials Group (AGITG) PAN1: A
randomized phase II study evaluating potential predictive
biomarkers in the treatment of metastatic pancreatic
cancer. Poster, American Society of Clinical Oncology
(ASCO) Annual Meeting, Chicago, June 2012.
J Fawcett, K M Sjoquist, R Padbury, C Christophi, N
Tebbutt, C Pilgrim, VGebski, N Wong, CE Aiken, D
Goldstein, Australasian Gastro-Intestinal Trials Group
(AGITG) ATTACHE: A phase III, multicenter, randomized
comparison of chemotherapy given prior to and postsurgical resection versus chemotherapy given post-surgical
resection for hepatic metastases from colorectal cancer.
Poster, ASCO Annual Meeting, Chicago, June 2012.
Price TJ, Hardingham J, Lee C, Wrin J, Townsend A,
Wilson K, Weickhardt A, Simes J, Murone C, Tebbutt N.
Analysis of PTEN in patients with advanced colorectal
cancer (CRC) receiving capecitabine alone or in
combination with bevacizumab with or without mitomycin
C in the phase III AGITG MAX trial. Journal of Clinical
Oncology, ASCO Annual Meeting Proceedings, Chicago,
June 2012; 30 (15 suppl): 3534.
Sjoquist KM, Lee C, Lord S, Chatfield M, Friedlander M,
Simes J, Marschner I. Progression-free survival (PFS) as a
surrogate end point for overall survival (OS) in first-line
treatment of advanced epithelial ovarian cancer (EOC).
Journal of Clinical Oncology, ASCO Annual Meeting
Proceedings 2012; 30 (15 suppl): 5081.
K Sjoquist, C Lee, S Lord, M Chatfield, M Friedlander, RJ
Simes, I Marschner. Progression Free Survival (PFS) is a
valid surrogate end point for overall survival (OS) in first
line treatment of advanced epithelial ovarian cancer (EOC).
Poster, ASCO Annual Meeting, Chicago, June 2012.
67
2012 National
K Sjoquist Interpreting Clinical Trial Data: Prognostic
and Predictive Factors
Invited speaker, Cancer
Pharmacy Practitioners Advanced Course November 2012,
Melbourne.
K Sjoquist Targeted Therapies – assessing and grading
common toxicities Invited speaker, Australasian
Gastrointestinal Trials Groups (AGITG) Annual Scientific
Meeting September 2012, Sydney.
2013 International
Michael M. Vickers, Dongsheng Tu, Chee Lee, Paul
Wheatley-Price, Wendy Parulekar, Michael Donald
Brundage, Malcolm J. Moore, Heather-Jane Au,
Christopher J. O’Callaghan, Derek J. Jonker, Jolie Ringash,
David Goldstein. Significance of baseline quality of life
scores in predicting clinical outcomes in an international
phase III trial of advanced pancreatic cancer: NCIC CTG
PA.3. Journal of Clinical Oncology, ASCO Annual Meeting
Proceedings 2013; 31, No 15_suppl (May 20 Supplement):
4053.
Martin R. Stockler, Felix Hilpert, Michael Friedlander,
Madeleine King, Lari B. Wenzel, Chee Lee, Florence Joly,
Nikolaus De Gregorio, Jose Angel Arranz Arija, Mansoor
Raza Mirza, Roberto Sorio, Ulrich Freudensprung, Vesna
Sneller, Gill Hales, Eric Pujade Lauraine and AURELIA
Investigators. Health-related quality of life (HRQoL) results
from the AURELIA trial evaluating bevacizumab (BEV) plus
chemotherapy (CT) for platinum-resistant recurrent ovarian
cancer (OC). ASCO Annual Meeting Proceedings 2013, 31
May-4 June 2103 Chicago, USA.
Angelina Tjokrowidjaja, Chee Lee, Martin R. Stockler.
Does chemotherapy improve survival in muscle-invasive
bladder cancer (MIBC)? A systematic review and metaanalysis (MA) of randomized controlled trials (RCT). Journal
of Clinical Oncology, ASCO Annual Meeting Proceedings
2013; 31 May-4 June 2103 Chicago, USA.
Chee Khoon Lee, Alan Coates, Malcolm Hudson, Karin
Ribi, Jürg Bernhard. Prognostic significance of qualityof-life scores in early stage and relapsed breast cancer:
results from seven randomized trials of the International
Breast Cancer Study Group. SABCS 2013. San Antonio
Breast Cancer Symposium 10-14 December 2013 San
Antonio, Texas USA.
68
Angelina Tjokrowidjaja, Chee K Lee, Nehmat Houssami,
Sally J Lord. Metastatic breast cancer (MBC) in young
women: A population-based cohort study to describe risk,
characteristics and prognosis. SABCS 2013. San Antonio
Breast Cancer Symposium 10-14 December 2013 San
Antonio, Texas USA.
Chee Khoon Lee, Lucy Davies, Val Gebski, Sally Lord,
Angelo Di Leo, Stephen Johnston, Charles Geyer Jr, David
Cameron, Michael Press, Catherine Ellis, John Simes, Paul
De Souza. HER2 Extracellular Domain (ECD): A Predictive
Marker of Lapatinib Treatment Benefit in Advanced
Breast Cancer. SABCS 2013. San Antonio Breast Cancer
Symposium 10-14 December 2013 San Antonio, Texas
USA.
Fox, P., B. Gao, B. Balakrishnar, A. M. Menzies, V. Gebski,
S. Coulter, C. Liddle, R. Hui, R. Kefford, J. Lynch, N.
Wilcken, R. L. Balleine and H. Gurney (2013). Factors
predicting endoxifen level in a tamoxifen dose escalation
study of breast cancer patients. ASCO. 31 May-4 June
2103 Chicago, USA.
Kirby, R., N. Alzahrani, J. Zhao, T. Chua, W. Liauw and D.
Morris (2013). P-0153 Peritonectomy results at St George
Hospital, Sydney Australia at 677 Procedures (Poster).
ESMO 15th World Congress on Gastrointestinal Cancer,
3–6 July 2013, Barcelona, Spain.
>
Department of Palliative Care, St George
Hospital & Calvary Health Care Sydney
Head of Department
Dr. Jan Maree Davis B.Med (Hons) FRACP FAChPM
Senior Medical
Dr. Frank Brennan MB BS FRACP FAcHPM
Dr. Judith Lacey MBBS FRACP FAcHPM
Dr. Christine Sanderson BA, BMBS, MPH, FRACP
Dr Linda Sheahan, Staff Specialist FRACP, M. Bioethics
Research
Professor Elizabeth Lobb PhD., MAppSci, B.AdEd.
Professor of Palliative Care (Allied Health), Calvary Health
Care Sydney and Cunningham Centre for Palliative Care;
Adjunct Professor, School of Medicine, the University of
Notre Dame, Sydney.
Dr. Christine Sanderson, BA, BMBS, MPH, FRACP
Staff Specialist in Palliative Medicine, Calvary Health Care
Sydney; Research Fellow, CareSearch, Flinders University
of South Australia, PaCCSC (Palliative Care Clinical Studies
Co-operative Investigator
Dr. Jane Mowll PhD, Research Associate
Ms. Lesley White, RN
Ms. Louise Bryce, RN
Ms. Victoria Tait, RN
Ms Mary Heidenreich RN
Ms. Anne Johnson, Senior Social Worker
Research Grants
Australian Government DIISR Research Collaborative
Research Network, University of Notre Dame Phillips J and
Lobb EA. Palliative Care: Translating evidence into action
to improve outcomes for palliative care patients and their
care givers. 2013 – 2017. $760,000.
Australian Government, DIISR Collaborative Research
Network, University of Notre Dame Monterosso L, Lobb
EA, Bulsara M. The effect of a nurse-led haematology
survivorship clinic on patient reported anxiety and unmet
informational needs: a multi-site Phase II randomised
controlled trial. 2013 – 2017 $494,774.
Cancer Council WA. Halkett GKB, Nowak A, Lobb EA,
Agar M, Miller L, Moorin R, Shaw T. Confidence to Care:
Pilot of a structured home-based support and education
for caregivers of people with high grade glioma. 20132014, $99,315.
Cancer Institute NSW. Sanderson C, Lobb EA, Upfront
Family Meetings for Community Palliative Care Services.
Evidence to Practice Grant 2013-2014. $50,000.
Cancer Institute NSW. Innovation Grant Lobb EA, Hanson
S, Sanderson C, Links M, Liauw W. Retrospective case
review and analysis of clinical journey of 100 consecutive
deaths in the Oncology Unit at St. George Hospital, 2013
$25,000.
Cancer & palliative Care Research & Evaluation Unit –
University of Western Australia. Monterosso L, Lobb EA,
Joske, D, White K, Young, K, Platt V, Krishnasamy, M,
Yates P, Johnson C. Defining unmet needs of haematology
survivors: An exploratory study to inform intervention
development. 2012. $19,985.
Churchill Fellowship, Sheahan, L. Exploring the Interface
between Palliative Care and Legalised Physician Assisted
Dying. 2012 $20000.
St. George Hospital Cancer Care Centre, Lobb EA, Lane
L, Lacey, J, Kelly B, Chochinov H, Agar M. AIs Kearsley
J, Liauw W, Mason C, Ingham J, Garrard J. A pilot study
of an intervention to facilitate communication between
couples on end-of-life issues.. 2012-2013. $42,000.
Cancer Institute NSW, Agar M (CI), Davidson P, Clark K,
Phillips J, Xuan W, Sanderson C, Lobb E, Lovell M, Luckett
T, Clayton J, Chye R, Liauw W, Chang S, Hardy J (AIs).
Improving Palliative Care through Clinical Trials (ImPaCCT)
- the NSW collaborative trials group in palliative care.
Cooperative Clinical Trial Grant. 2013-2016. $295,484.
Mary Philippa Brazill Foundation, Phillips JL, Lobb EA,
Lynch S, Ingham J. A study to build the capabilities of
Australian undergraduate medical and nursing students to
respond to requests to hasten death.. 2013. $4,000
Research Projects in Progress
A pilot study of an intervention to facilitate communication
between couples on end-of-life issues Lobb EA, Lane L,
Lacey, J, Kelly B, Chochinov H, Agar M. AIs Kearsley J,
Liauw W, Mason C, Ingham J, Garrard J.
Pilot of a structured home-based support and education
for caregivers of people with high grade glioma. Halkett
GKB, Nowak A, Lobb EA, Agar M, Miller L, Moorin R,
Shaw T.
69
Too much, too soon? The impact of treatment-focused
genetic testing in patients newly diagnosed with breast
cancer. CIs Meiser B, Mitchell G, Tucker K, Saunders C,
Geelhoed E, Hopper J, Watts K. AIs: Kirk J, Lobb EA,
Barlow-Stewart K, Friedlander M, Thewes B, Southey M,
Gleeson M, Kelly P.
Palliative Care: Translating evidence into action to
improve outcomes for palliative care patients and their
care givers. Phillips J and Lobb EA.
The effect of a nurse-led haematology survivorship clinic
on patient reported anxiety and unmet informational
needs: a multi-site Phase II randomised controlled trial.
Monterosso L, Lobb EA, Bulsara M.
Confidence to Care: Pilot of a structured home-based
support and education for caregivers of people with high
grade glioma. Halkett GKB, Nowak A, Lobb EA, Agar M,
Miller L, Moorin R, Shaw T.
Upfront Family Meetings for Community Palliative Care
Services. Sanderson C, Lobb EA.
Retrospective case review and analysis of clinical journey
of 100 consecutive deaths in the Oncology Unit at St.
George Hospital. Lobb EA, Hanson S, Sanderson C, Links
M, Liauw W.
Defining unmet needs of haematology survivors: An
exploratory study to inform intervention development.
Monterosso L, Lobb EA, Joske, D, White K, Young, K, Platt
V, Krishnasamy, M, Yates P, Johnson C.
A pilot study of an intervention to facilitate communication
between couples on end-of-life issues. Lobb EA, Lane L,
Lacey, J, Kelly B, Chochinov H, Agar M. AIs Kearsley J,
Liauw W, Mason C, Ingham J, Garrard J.
Improving Palliative Care through Clinical Trials (ImPaCCT)
- the NSW collaborative trials group in palliative care. Agar
M (CI), Davidson P, Clark K, Phillips J, Xuan W, Sanderson
C, Lobb, E, Lovell M, Luckett T, Clayton J, Chye R, Liauw
W, Chang S, Hardy J (AIs).
A study to build the capabilities of Australian
undergraduate medical and nursing students to respond
to requests to hasten death. Phillips JL, Lobb EA, Lynch S,
Ingham J.
Who grieves: identifying those most likely to be affected
by the death of a person with a terminal condition. Phillips
J, Currow D, Lobb EA.
Exploring the Interface between Palliative Care and
Legalised Physician Assisted dying – Cross sectional Data
collection from the Australian and New Zealand context.
Sheahan L.
70
Original Peer-Reviewed Publications
2012
Brennan FP. John Keats and Wilfred Owen – Mortality,
Mystery, and the Pursuit if Truth: Lessons for Palliative
Care. Journal of Palliative Care 2012; 28(2): 116-119.
Brennan FP. The lonely impulse of delight. Journal of
Palliative Care 2012; 28(4): 297-300.
Josland E, Brennan FP, Anastasiou A, Brown MA.
Developing and sustaining a renal supportive care service
for people with end-stage kidney disease. Renal Society of
Australasia Journal 2012; 8(1): 12-18.
Lobb, EA. The challenge of giving bad news. Medicine
Today 2012, Vol 13 (9).55-57. Invited paper.
Rando, T.A., Doka, K.J., Fleming, S., Franco, M.H., Lobb,
EA., Murray Parkes, C. Steele, R. A Call to the Field,
Omega – Journal of Death & Dying, 2012. 64 (4); 251255. Invited paper.
Butow,PN, Lobb, EA, Jefford, M, Goldstein, D.,
Eisenbruch, M., Girgis, A., King, M., Sze, M., Aldridge,
LJ, Schofield, P. A bridge between cultures: interpreters’
perspectives of consultations with migrant oncology
patients. Supportive Care in Cancer, 2012. 20(2):235 –
244.
Hudson, P., Lobb, EA, Thomas. K., Zordan, R., Trauer, T.,
Quinn, K., Williams, A., Summers, M. Psycho-educational
group intervention for family caregivers of hospitalised
palliative care patients: pilot study. Journal of Palliative
Medicine 15 (3) 277-281. 2012.
Zilliacus E, Meiser B, Gleeson M, Watts K, Tucker K, Lobb
EA, Mitchell G Are we being overly cautious? A qualitative
inquiry into the experiences and perceptions of treatmentfocused germline BRCA genetic testing amongst women
recently diagnosed with breast cancer Supportive Care in
Cancer (2012) 20(11):2949-58.
Halkett, G., Kristjanson, L., Lobb, EA., Little, J., Jiwa,
M., Shaw, T., Taylor, M.,Spry, N. Information needs and
preferences of women as they proceed through radiation
therapy for breast cancer. Pt Edu & Couns, 2012;86(3):396404.
Hudson, P., Trauer, T., Lobb, EA., Williams, A., Zordan,
R., Quinn, K., Williams, A., Summers, M. Supporting
family caregivers of hospitalized palliative care patients:
Effectiveness of a psycho-educational group intervention.
BMJ Supportive & Palliative Care (2012). doi:10.1136/
bmjspcare-2011-000131.
Coupe NA, Lacey J, Sanderson C. Unique
Manifestations of Catecholamine Release in Malignant
Pheochromocytoma: An Experience Within an Inpatient
Palliative Care Unit. J Pain Symptom Manage. 2012
May;43(5):967-72.
Newton PJ, Davidson PM, Sanderson C. An online survey
of Australian physicians reported practice with the off-label
use of nebulised frusemide. BMC Palliative Care 2012,
11:6.
Sheahan L, Da Silva M, Czoli C, Zlotnik Shaul R. A
Canadian Perspective on a Child’s Consent to Research
within a Context of Family Centered Care: From
Incompatibility to Synergy. Journal of Clinical Research
and Bioethics 2012: 3 (1).
2013
Brennan FP. “Clock Without Hands” – Carson McCullers
and the Rhythm of Living and Dying. American Journal of
Hospice and Palliative Medicine 2013; 30(3):312-316.
Urban K, Brennan FP. Patients who withdraw from dialysis
in a Sydney centre with palliative care support : who, why,
and how they die. Progress in Palliative Care. 2013; 21(6):
325-330.
Brennan FP. Conscientious Objector – Edna St Vincent
Millay, mortality and the nature of Palliative Care. Journal
of Palliative Care 2013; 29(2): 123-125.
Brennan FP, Brown M. The ethics of dialysis – an alliance
of Nephrology, Palliative Medicine and Ethics. Quarterly
Journal of Medicine 2013; 106(5): 397-400.
Brennan FP. The New World of Ourselves. Journal of
Palliative Care. 2013; 29(4): 258-259.
Brennan FP. Ethical Principles for Patients, Families and
Doctors to Consider. Nephrology 2013; 18: 413-414.
Brennan FP, Siva B, Crail S. Appropriate Assessment of
Symptom Burden and Provision of Patient Information.
Nephrology 2013; 18: 418-421.
Brennan FP. Holistic Palliative Care Approach - Physical,
Spiritual, Religious and Psychological Needs. Nephrology
2013;18: 421-423.
Siva B, Brennan FP. Inappropriate Interventions in the
Dying Patient. Nephrology 2013; 18: 423-424.
Stewart C, Brennan FP. Legal Issues Concerning
Withholding and Withdrawal of Dialysis. Nephrology 2013;
18: 444-449.
Lim CED, Siow S, Ho KEH, Chua JL, Chong N, Cheng L,
Kwok, Brennan FP, Cigolini M. Advance Care planning in
haemodialysis patients. Protocol Information. Cochrane
Reviews. Review number 294. September 2013.
Brennan FP, Murrell DF. Report from the Inaugural
Australian Pruritus Symposium, Sydney, Australia, August
10 2013. Acta Derm Venereol 2013. Oct 24 [Epub ahead
of publication].
Kearsley, JH, Lobb, EA. “It’s not a disease we treat but a
person:” Reflections of medical students from their first
rotation to an oncology and palliative care unit. Journal of
Palliative Care. 29:3 / 2013; 231–235.
Lobb, EA, Lacey, J., Kearsley, J., Liauw, W., White,
L., Hosie, A. Living with advanced cancer and an
uncertain disease trajectory: An emerging population
in palliative care? BMJ Supportive & Palliative Care.
Published on-line April 2013; 2013;0:1–6. doi:10.1136/
bmjspcare-2012-000381
Watts, K.J., Meiser, B., Wakefield, C., Barratt, A., Howard,
K., Cheah, B.C., Mann, G.J., Lobb, EA, Gaff, C.L., Patel,
M.I. Online prostate cancer screening decision aid for
at-risk men: A randomized trial, Health Psychology, 12
June 2013.Patel MI. Health Psychology, Health Psychology
11/2013, DOI:10.1037/a0034405.
Sanderson, C., Lobb, EA, Mowll, J. Butow, P., Price, M.
Signs of post-traumatic stress disorder in caregivers
following an expected death: a qualitative study’ as a
factual descriptor of the study. Palliative Medicine, 2013,
27(7), 625-631.
Sanderson C, Hardy J, Spruyt O, Currow D Placebo
and nocebo effects in randomised controlled trials - the
implications for research and practice. Journal of Pain and
Symptom Management: Vol. 46 No. 5 November 2013.
Heidenreich MT, White K, Kuen Koo F The experience
of Chinese immigrant women in caring for a terminally
ill family member in Australia, Collegian 03 July 2013
(10.1016/j.coleg.2013.06.002).
Other published material
2012
Lobb, EA. Chapter: “The selfsame well: Perspectives on
human suffering in loss, grief and bereavement”. Book
– Perspectives on Human Suffering, proceedings from
Colloquium on Human Suffering, Hobart, February 2012.
Elservier. Editors J. Malpas and N. Lickiss, C. Sanderson.
Sanderson, C. Webpage for CareSearch. Dementia
(including evidence summaries on palliative care
challenges; caregivers and care settings; prognosis and
advance care planning; symptom management.) http://
www.caresearch.com.au/caresearch/tabid/2785/Default.
aspx, accessed May 29, 2013.
Brennan FP. Renal Palliative Care – A Reader. 2012. Vision
Media, Sydney.
Brennan FP. Suffering seeks a voice. In: Malpas J and
Lickiss N (eds). Perspectives on Human Suffering. 2012.
Springer Publishing.
71
Presentations at Scientific Meetings and
Conferences
2012 – International
Lobb, EA, Price, M., McGowan, N., Mowll, J Butow, PN.
“Palliative care services and a ‘good death’; learning
from family care-givers” 19th International Congress on
Palliative Care, Montreal 9-12 October
Kearsley, J & Lobb, EA. “It is not a disease we treat but
a person”: Reflections of medical students on their first
rotation to an oncology and palliative care term”. 19th
International Congress on Palliative Care, Montreal 9-12
October, 2012
Lobb, EA, Price, M., McGowan, N., Mowll, J Butow, PN.
“Palliative care services and a ‘good death’; learning
from family care-givers” 19th International Congress on
Palliative Care, Montreal 9-12 October.
Hudson, P, Trauer, T, Lobb, EA, Zordan, R. Williams, A.,
Quinn, K., Summers, M., Thomas, K., Supporting family
caregivers of hospitalized palliative care patients: A
psycho-educational group intervention. 19th International
Congress on Palliative Care, Montreal 9-12 October.
Brennan, FP. The management of pain and other
symptoms in patients with End Stage Kidney Disease.
Australian and New Zealand Society of Nephrology
Meeting, Auckland, New Zealand, August 26.
Heidenreich MT, White K, Kuen Koo F. Caring Is a Lonely
and Isolating Experience: Immigrant Chinese Women’s
Experience in Caring for a Terminally Ill Relative at Home
in New South Wales, Australia. 19th International Congress
on Palliative Care. Montreal, Canada. October.
2012 – National
Mowll, J., Lobb, EA, Price, M., McGowan, N., Butow, PN.
Features of gender and grief reported in the experiences
of family care-givers six months after a family member’s
death from ovarian cancer. Clinical Oncological Society of
Australasia Annual Scientific Meeting, Melbourne
Halkett, G., Nowak, A., Lobb, EA, Long, A. Fournier,
C., Nowak, A. Carers of patients with HGG are more
distressed than the patients: Understanding the
experience of caring for people living with High Grade
Glioma Clinical Oncological Society of Australasia Annual
Scientific Meeting, Melbourne.
Calford, BR, Zilliacus, E., Meiser, B., Lobb, EA, Spigelman,
A, Tucker, K. The Process and Content of Tele-health
Cancer Genetic Counselling, Clinical Oncological Society
of Australasia Annual Scientific Meeting, Melbourne.
Zordan, R., Remedios, C., Price, M., Lobb, EA, Hall, C.,
Hudson, P. The prevalence and predictors of threshold and
72
sub-threshold prolonged grief disorder (PGD) amongst
bereaved cancer caregivers: Implications for bereavement
services Clinical Oncological Society of Australasia Annual
Scientific Meeting, Melbourne.
Brennan, FP. Palliative Care Physicians don’t just palliate.
Renal Home Therapies Conference, Sydney. March 15.
Brennan, FP. How Do We Stop ? Withdrawal From Dialysis.
Renal Home Therapies Conference, Sydney. March 15.
Brennan, FP. Renal Supportive Care – An Overview and
Recent Developments. NSW Palliative Care Education Day,
Royal Prince Alfred Hospital. May 25.
Brennan, FP. Symptom management in patients
with Chronic Kidney Disease. Renal Supportive Care
Symposium, St George Hospital. August 10.
Brennan, FP. Nephrology- Medical, Ethical and Legal
Dimensions. Renal Supportive Care Symposium, St George
Hospital. Case based discussion with Dr Su Crail, Professor
Cameron Stewart and Bernadette Tobin. August 10.
Brennan, FP.. What is new in Renal Supportive Care ? (Copresented with Liz Josland and a video presentation by
Gemma Collett) August 10.
Brennan, FP..Symptom management in patients
with Chronic Kidney Disease. Renal Supportive Care
Symposium, St George Hospital. August 10.
2013 - International
Lobb, EA, Lane, L., Lacey, J., Chochinov, HM, Kelly, B.
Agar, M., Mowll, J., Links, M., Kearsley, JH, Liauw, W.,
Lynch, J. A pilot study of an intervention for couples to
facilitate communication about end of life issues where
one member of the couple has incurable cancer. 15th
World Congress on Psycho-oncology, Rotterdam, 4-8th
November (oral).
Sanderson, C, Lobb, EA, Mowll, J, Butow, PN, McGowan,
N., Price, MA. The sights and sounds of palliative care:
Caregivers’ experiences at the deathbed: A qualitative
study. 15th World Congress on Psycho-oncology,
Rotterdam, 4-8th November. (poster)
Lobb, EA, Lacey, J, Liauw, W, White, L., Hosie, A, Kearsley,
J. A re-assessment of meaning-making in patients with
early-diagnosed incurable cancer. 15th World Congress on
Psycho-oncology, Rotterdam, 4-8th November.
Hosie, A., Phillips, J., Agar, M., Lobb, EA, Davidson,
P. Exploring recognition and assessment of delirium
symptoms by palliative care nurses using the Critical
Incident Technique. 8th Annual Meeting of the European
Delirium Association; Leuven, Belgium, September 20-21
(oral).
Brennan FP, Palliative Care in End Stage Renal Disease.
Asia Pacific Hospice and Palliative Care Network
Conference, Bangkok, Thailand. October 11.
Brennan FP, Renal Supportive Care in adult patients –
An Overview . Paediatric Palliative Care Symposium,
Westmead Childrens’ Hospital. March 7.
Brennan FP,. Engaging Palliative care in non-cancer
patients. Asia Pacific Hospice and Palliative Care Network
Conference, Bangkok, Thailand. [Plenary speech] October
12.
Brennan FP, The experience of establishing a Renal
Supportive Care Service. Nephrology Scientific
Symposium. Melbourne, Victoria. April 20.
Brennan FP, Morality and Ethics in the withdrawal of
treatment. Asia Pacific Hospice and Palliative Care
Network Conference, Bangkok, Thailand. October 13.
Brennan FP, Renal Supportive Care – An Overview. All
Ireland Palliative Care Institute, Dublin, Ireland. April 29.
2013 National
Lobb, EA, Sanderson, C, Mowll, J., Butow, PN, Price, M.
“The Sights and Sounds of Palliative Care” Caregiver’s
experiences at the deathbed: A qualitative study”. 12th
Australian Palliative Care Conference National Convention
Centre in Canberra, 3-6 September.
Sanderson, C., Johnson, A., Lobb, EA, Mowll, J. “Do
early patient-centered family meetings reduce patient and
family distress at first admission for in-patient palliative
care”? 12th Australian Palliative Care Conference the
National Convention Centre in Canberra, 3-6 September.
Hosie, A., Phillips, J., Agar, M., Lobb, EA, Davidson,
P. Exploring recognition and assessment of delirium
symptoms by palliative care nurses: a qualitative study”.
12th Australian Palliative Care Conference, National
Convention Centre in Canberra, 3-6 September.
Sanderson, C., Johnson, A., Lobb, EA, Mowll, J. Studying
family meetings: what have we learned and what should
we measure? 12th Australian Palliative Care Conference
to be held at the National Convention Centre in Canberra,
3-6 September.
Kadwell, L., Usher, J., Gilbert, E, Lobb EA. “Talking about
sexuality and intimacy is everyone’s business” Health
professionals communication in the context of cancer and
palliative care” 12th Australian Palliative Care Conference,
National Convention Centre in Canberra, 3-6 September.
Sheahan, L., Churchill Fellowship report findings: Exploring
the Interface between Palliative care and Legalised
Physician.
Assisted Suicide/Voluntary Euthanasia. Palliative Care
Australia Conference, Canberra, August.
Brennan FP, Renal Supportive Care – An Overview.
Department of Nephrology, John Hunter Hospital,
Newcastle. February 14.
Brennan FP, Pain in non-malignant diseases including End
Stage Kidney Disease. Pain Symposium. Pain Institute
Royal North Shore Hospital, Sydney. May 4.
Brennan FP, Renal Supportive Care – An Overview. The
Physicians’ Forum. Concord Hospital, Sydney, July 11.
Brennan FP, What is new in Renal Supportive Care? Renal
Supportive Care Symposium, St George Hospital, Sydney,
August 9.
Brennan FP, The pathogenesis and management
of Restless Legs Syndrome. Renal Supportive Care
Symposium, St George Hospital, Sydney, August 9.
Brennan FP, The pathogenesis of pruritus. Pruritus
Symposium. St George Hospital, Sydney. August 10.
Brennan FP, The pathogenesis and management of
Uraemic Pruritus. Pruritus Symposium. St George Hospital,
Sydney, August 10.
Brennan FP, Management and Advance Care Planning in
patients with End Stage Kidney Disease. Clinical Ethics
Forum - Ethics, End of Life and Advance Care Planning.
Royal Hospital for Women, Randwick, Sydney. September
27.
Heidenreich MT, White K, Kuen Koo F Caring Is a Lonely
and Isolating Experience: Immigrant Chinese Women’s
Experience in Caring for a Terminally Ill Relative at Home
in New South Wales, Australia. 12th Australian Palliative
Care Conference. Canberra, ACT, 3-6 September.
Heidenreich MT, White K, Kuen Koo F. Chinese family
obligations: Confucian cultural beliefs influencing palliative
care for Chinese families and female carers in Australia.
12th Australian Palliative Care Conference. Canberra, ACT,
3-6 September.
Community Engagement
Lobb, EA. Appointed to Executive Committee of ACI
Palliative Care Network 2012.
Lobb, EA. Appointed member of Expert Advisory Group
on Bereavement Search filter – CareSearch, 2012.
Kearsley, J., Lacey, J., Lobb, EA, Sanderson, C., White,
L. Organising Committee – Whole Person Care Public
Lecture – Professor Eric Cassell, UNSW, 2nd September,
2013.
73
Kearsley, J., Lacey, J., Lobb, EA, Sanderson, C., White, L.
Organising Committee – Whole Person Care Symposium,
Sydney, May, 2012.
74
>
Department of Radiation Oncology
Professor J H Kearsley MBBS (Hons Syd) FRACP FRANZCR
Junli (Cindy) Deng PhD student
Ning (Sophia) Li Visiting Fellow (Medical Oncologist)
Oliver Fio ILP student
Senior Medical
Allied Health
A/Professor Peter Graham MBBS, FRANZCR, Cert
Bioethics, Grad Dip Medical Statistics
Dr Joseph Bucci MBBS FRACP FRANZCR
Dr Catherine Clark MBBS FRANZCR
Dr Yaw Chin BSc (Med) FRANZCR
Dr Eric Hau BSc (Med), MBBS, Grad Cert (Biostat),
FRANZCR
Julia Maclean PhD M.Sc (Medicine) B.App. Sc (Speech
Pathology), BA (Linguistics/Psychology)
Wendy Relf, M. HealthSc (Comms), B.App. Sc (Speech
Pathology), BA (Linguistics/Psychology).
Head of Department
Junior Medical
Dr Nadine Beydoun
Dr Eric Hau
Dr Ariyanto Pramana
Dr Mimi Tieu
Dr Dominique Lee
Dr Alex Petruvski
Dr Chelsea Connor
Research Staff - Clinical Trials Unit
Peter Fink BSc, Clinical Trials Unit Manager –Radiation
Oncology
Trials Co-ordinators
Helen Cox BSc
Sima Don PhD
Faith Koh MPH
Mary MacFarlane RN
Kylie Melki - BBioTech
Sharon Parkes BSc
Xiaolu Wang M HealthAdmin
Xiaobing Ma BMed
Victoria Stevens BPharm
Senior Researchers
A/Professor Yong Li: Principal Scientific Officer and Head
of Cancer Research Program
Dr Jingli (Helen) Hao: Hospital Scientist, Conjoint Lecturer
of UNSW
Research Students
Julia Beretov Scientific Officer and PHD student
Lei (Nancy) Chang PhD student
Research Grants
NHMRC Project Grant, Principal Investigators: Cook I,
Szczesniak M, Maclean J, Graham P, Omari T. Predicting
dysphagia-related complications and improving outcomes
in patients treated with head and neck radiotherapy.
$301,624 (2012-2014).
NHMRC Career Development Fellow (Level 2) Principal
Investigators: A/Professor Yong Li
Identification of novel biomarkers in urine to improve
diagnosis and monitor progression in prostate cancer.
$417,000 (2010-2014).
ARC-linkage Grant Principal Investigators: A/Professor
Yong Li, Dr Paul Cozzi, M. Willcox, B. Walsh. Proteomic
study of urine to discover novel biomarkers for human
prostate cancer.
$150,000 (2010-2013).
Cancer Australia / National Breast Cancer Foundation,
Principal Investigators: Holloway L, Metcalfe P, Lazarus
E, Delaney G, Batumalai V, Vial P, Koh E-S, Associate
Investigators: Quinn A, Jameson M, Hargreaves B, Moran
C, Keall P, Collins L, Shafiq J, Rozenfeld A, Lonergan
D, Papadatos G, Lim K, Ahern V, Drummond R, Tiver K,
Graham P, Ramsay J. Breast MRI in radiotherapy planning.
$391,596 2012-2015.
Cancer Australia Project Grant, Principal Investigators:
A Prof P Graham, Prof G Delaney, Dr E Millar, Dr Anne
Capp. AIs: Prof R Sutherland, Dr S Carroll, Dr J Harvey, Dr
J Lynch , Dr R Tse. TROG 08.06; A randomised comparison
of anastrozole commenced before and continued during
adjuvant radiotherapy for breast cancer versus anastrozole
and subsequent anti-oestrogen therapy delayed until
after radiotherapy. (STARS - Study of Anastrozole and
Radiotherapy Sequencing), $660,000 (2010-2012).
75
Research Projects in Progress
A randomised comparison of Anastrozole commenced
before and continued during adjuvant radiotherapy
for breast cancer versus Anastrozole and subsequent
anti-oestrogen therapy delayed until after radiotherapy.
Principal Investigator: A/Professor Peter Graham.
Determining the needs of Grade III-IV High Grade Glioma
patients. Principal Investigator: Professor John Kearsley.
A collaborative randomised phase III trial: The timing of
intervention with androgen deprivation in prostate cancer
patients with a rising PSA. Principal Investigator: Dr Joseph
Bucci.
Randomised trial investigating the effect on survival and
PSA control of different durations of adjuvant androgen
deprivation in association with definitive radiation
treatment for localised carcinoma of the prostate (RADAR).
Principal Investigators: Dr Joseph Bucci.
A phase III study of regional RT in early breast cancer
(NCIC MA20). Principal Investigator: A/Professor Peter
Graham.
STARS Pilot Breast Trial: A randomised comparison of
Anatrazole commenced before and continues during
radiotherapy for breast cancer versus Anastrazole and
subsequent Anti-Oestrogen therapy delayed until after
radiotherapy. Principal Investigator: A/Professor Peter
Graham.
A randomised comparison of breast conservation with or
without lumpectomy radiotherapy boost
Principal Investigator: A/Professor Peter Graham
Pulmonary Fibrosis following breast conservation adjuvant
radiotherapy: the modifying effects of systemic therapies
(chemotherapy and Tamoxifen. Principal Investigator: A/
Professor Peter Graham.
A Randomised Phase III Study of Radiation Doses and
Fractionation Schedules in Non-Low Risk Ductal Carcinoma
In Situ (DCIS) of the Breast. Principal Investigator: A/
Professor Peter Graham.
A randomised phase II/III trial of preoperative
chemoradiotherapy versus preoperative chemotherapy
for resectable gastric cancer. Principal Investigator: Dr Yaw
Chin.
RAVES: Radiotherapy - Adjuvant Versus Early Salvage. A
phase III multi-centre randomised trial comparing adjuvant
radiotherapy (RT) with early salvage RT in patients with
positive margins or extraprostatic disease following radical
prostatectomy. Principal Investigator: Dr Joseph Bucci.
Phase II Study of Accelerated Partial Breast Irradiation
Using Interstitial Multi-Catheter High Dose Rate
Brachytherapy. Principal Investigator: Dr Yaw Chin.
76
Feasibility of Using Polyethylene Glycol Hydrogel to
Increase Prostate-Rectum Separation and Its Impact
on Rectal Dose during Radiation Therapy. Principal
Investigator: Dr Nadine Beydoun.
Evaluating the Utility of a Patient Decision Aid for
Prospective Participants in the TROG RAVES Prostate
Cancer Trial (TROG 08.03) Principal Investigator: Dr
Joseph Bucci.
A Phase II Study of Stereotactic ablative Body
Radiotherapy(SABR) for Stage I NSCLC. Principal
Investigator: Dr Eric Hau.
Identification of novel biomarkers in tears for breast cancer
diagnosis and monitoring. Principal Investigators: A/
Professor Yong Li, A/Professor Peter Graham, M Willcox , V
Wasinger and Professor John Kearsley .
PI3K/Akt/mTOR signalling pathway in prostate cancer
radioresistance. Principal Investigators: A/Professor Yong
Li, A/Professor Peter Graham, Professor John Kearsley and
Dr Joseph Bucci.
Identification of novel biomarkers associated with prostate
cancer radioresistance. Principal Investigators: A/Professor
Yong Li, A/Professor Peter Graham, Dr Paul Cozzi,
Professor John Kearsley and Dr Joseph Bucci.
Investigating the roles of CD44v6 and CD326 in prostate
cancer metastasis and chemo- radioresistance. Principal
Investigators: A/Professor Yong Li, Dr Paul Cozzi, A/
Professor Peter Graham, and Professor John Kearsley.
Predicting dysphagia-related complications and improving
outcomes in patients treated with head and neck
radiotherapy. Principal Investigators: Professor Ian Cook,
Dr Michal Szczesniak, Dr Julia Maclean, A/Professor
Peter Graham, Dr Taher Omari. Prospective, randomized
controlled trial of cricopharyngeal dilatation in postlaryngectomy dysphagia. Principal Investigators: Dr Peter
Wu, Professor Ian Cook, Dr Michal Szczesniak, Dr Julia
Maclean.
Influence of Altered Pharyngo-esophageal Biomechanical
Parameters on Swallowing and Speech Function in
Laryngectomees. Principal Investigators: Ms Teng Zhang,
Professor Ian Cook, Dr Michal Szczesniak, A/Prof Paul
Bertrand, Dr Julia Maclean.
Original Peer-Reviewed Publications
2012
Beydoun, N., Graham, P. H., & Browne, L. (2012).
Metastatic cutaneous squamous cell carcinoma to the
axilla: A review of patient outcomes and implications for
future practice. World Journal Oncology, 3(5), 217-226.
Graham, P., Plant, N., Graham, J., Browne, L., Borg, M.,
Capp, A., Delaney, G., Harvey, J., Kenny, L., Francis, M.,
& Zissiadis, Y. (2012 ). Digital photography as source
documentation of skin toxicity: An analysis from the
Trans Tasman Radiation Oncology Group (TROG) 04.01
Post-Mastectomy Radiation Skin Care. Journal of Medical
Imaging and Radiation Oncology, 56, 458-463.
Hao, J., Madigan, M. C., Khatri, A., Power, C. A., Hung,
T.-T., Beretov, J., Chang, L., Xiao, W., Cozzi, P. J., Graham,
P. H., Kearsley, J. H., & Li, Y. (2012). In Vitro and In Vivo
Prostate Cancer Metastasis and Chemoresistance Can Be
Modulated by Expression of either CD44 or CD147. PLoS
ONE, 7(8), e40716.
Hau, E., Browne, L. H., Khanna, S., Cail, S., Chin, Y.,
Clark, C., Inder, S., Szwajcer, A., & Graham, P. (2012).
Radiotherapy Breast Boost With Reduced Whole-Breast
Dose Is Associated With Improved Cosmesis: The Results
of a Comprehensive Assessment From the St. George and
Wollongong Randomized Breast Boost Trial. International
Journal of Radiation Oncology Biology Physics, 82(2), 682689.
Hau, E., & Graham, P. (2012). A brief review on the
biological effects of radiation on cells. The Radiographer,
Volume 59(3), 89-97.
Kearsley, J. (2012). An exquisite presence (after Buber).
Palliative & Supportive Care, 10(04), 307-307.
Ni, J., Cozzi, P., Duan, W., Shigdar, S., Graham, P., Kearsley,
J., & Li, Y. (2012). Role of the EpCAM (CD326) in prostate
cancer metastasis and progression. Cancer and Metastasis
Reviews, 31(3-4), 779-791.
Pramana, A., Browne, L., & Graham, P. H. (2012).
Metastatic cutaneous squamous cell carcinoma to parotid
nodes: The role of bolus with adjuvant radiotherapy.
Journal of Medical Imaging and Radiation Oncology,
56(1), 100-108.
Xiao, W., Graham, P., Power, C., Hao, J., Kearsley, J.,
& Li, Y. (2012). CD44 is a biomarker associated with
human prostate cancer radiation sensitivity. Clinical and
Experimental Metastasis, 29(1), 1-9.
Xiao W, Graham P, Power C, Hao JL, Kearsley J, Li Y.
CD44 is biomarker correlated with human prostate cancer
radiation sensitivity. Clinical & Experimental Metastasis
2012; 29:1-9.
Shigdar S, Lin J, Li Y, Yang CJ, Wei M, Zhu Y, Liu H, Duan
W. Cancer stem cell targeting: the next generation of
cancer therapy and molecular imaging. Therapeutic
Delivery 2012; 3:227-244.
Hao J, Madigan M, Khatri A, Power C, Hung T, Beretov
J, Chang L, Xiao W, Cozzi P, Graham P, Kearsley J, Li
Y. In vitro and in vivo prostate cancer metastasis and
chemoresistance can be modulated by expression of
either CD44 or CD147. PLoS ONE 2012;7:e40716.
Ni J, Cozzi PJ, Duan W, Shigdar S, Graham P, Kearsley
J, Li Y. Role of the EpCAM (CD326) in prostate cancer
metastasis and progression. Cancer and Metastasis
Reviews 2012; 31:779-791.
Chang L, Graham P, Hao JL, Ni J, Bucci J, Cozzi P, Kearsley
J, Li Y. Epithelial mesenchymal transition (EMT) is involved
in the prostate cancer radiation resistance. Asia-Pacific
Journal of Clinical Oncology 2012; 8(Supplement 3): 333.
2013
Ball, D. L., R. J. Fisher, B. H. Burmeister, M. G. Poulsen, P.
H. Graham, M. G. Penniment, S. K. Vinod, H. E. Krawitz,
D. J. Joseph, G. C. Wheeler and B. E. McClure (2013). The
complex relationship between lung tumor volume and
survival in patients with non-small cell lung cancer treated
by definitive radiotherapy: A prospective, observational
prognostic factor study of the Trans-Tasman Radiation
Oncology Group (TROG 99.05). Radiotherapy and
Oncology 106(3): 305-311.
Beydoun, N., Bucci, J., Chin, Y., Spry, N., Newton, R.,
and Galvão, D., (2013). Prospective study of exercise
intervention in prostate cancer patients on androgen
deprivation therapy. Journal of Medical Imaging
and Radiation Oncology: epub, DOI: 10.1111/17549485.12115.
Chao, H., Wang, L, Hao, J, Ni, J, Chang, Li, Graham, P,
Kearsley, J and Li, Y (2013). Low dose histone deacetylase
inhibitor, LBH589, potentiates anticancer effect of
docetaxel in epithelial ovarian cancer via PI3K/Akt pathway
in vitro. Cancer Letters 329(1): 17-26.
Chao, H., Wang, L, Hao, J, Ni, J, Chang, Li, Graham, P,
Kearsley, J and Li, Y (2013). Low dose histone deacetylase
inhibitor, LBH589, potentiates anticancer effect of
docetaxel in epithelial ovarian cancer via PI3K/Akt pathway
in vitro. Cancer Letters 329(1): 17-26.
Graham, P, Plant N, Graham J, L. Browne, M. Borg, A.
Capp, G. P. Delaney, J. Harvey, L. Kenny, M. Francis and
Y. Zissiadis (2013). A Paired, Double-Blind, Randomized
Comparison of a Moisturizing Durable Barrier Cream to
10% Glycerine Cream in the Prophylactic Management
of Postmastectomy Irradiation Skin Care: Trans-Tasman
Radiation Oncology Group (TROG) 04.01. International
Journal of Radiation Oncology Biology*Physics 86(1): 4550.
Hao, J., Ni, J, Graham, P, Cozzi, P, Bucci, J. Kearsley, J
and Li, Y (2013). “The CD44 Isoforms in Prostate Cancer
Metastasis and Progression. World Journal of Cancer
Research 1(1): 3-14.
Hau, E, Browne L., Capp A., Delaney G. P, Fox, C,
Kearsley, J, Millar, E. Nasser, E, Papadatos G and Graham,
77
P (2013). The impact of breast cosmetic and functional
outcomes on quality of life: long-term results from the St.
George and Wollongong randomized breast boost trial.
Breast Cancer Research and Treatment: 1-9.
Haworth, A., L. Wilfert, D. Butler, M. A. Ebert, S. Todd,
J. Bucci, G. M. Duchesne, D. Joseph and T. Kron (2013).
Australasian brachytherapy audit: Results of the ‘end-toend’ dosimetry pilot study. Journal of Medical Imaging
and Radiation Oncology: Volume 57, Issue 4, pages
490–498, August 2013.
Lobb, E. A., J. Lacey, J. Kearsley, W. Liauw, L. White
and A. Hosie (2013). “Living with advanced cancer and
an uncertain disease trajectory: an emerging patient
population in palliative care?” BMJ Supportive & Palliative
Care. Vol 27, No 34, 2009: pp. 5757-5762.
Chao H, Wang L, Hao J, Ni J, Chang L, Graham P, Kearsley
J, Li Y. Combination of the histone Deacetylase inhibitor
LBH589 with Docetaxel is highly effective in treating
human epithelial ovarian cancer. Cancer Letters. 2013;
329:17-26.
Hao JL, Ni J, Graham P, Cozzi P, Bucci J, Kearsley J and Li
Y. The CD44 isoforms in prostate cancer metastasis and
progression. World Journal of Cancer Research 2013; 1:112.
Xiao W, Graham P, Hao JL, Chang L, Ni J, Power C, Dong
Q, Kearsley J and Li Y. Combination therapy with the
histone Deacetylase inhibitor LBH598 and radiotherapy is
an effective regimen for prostate cancer cells. PloS ONE.
2013; 8:e74253.
Shigdar S, Qian C, Lv L, Pu C, Li Y, Li L, Marappan M, Li J,
Wang L, Duan W. The use of sensitive chemical antibodies
for diagnosis: detection low levels of EpCAM in breast
cancer. PloS ONE. 2013; 8:e57613.
Shigdar S, Qian L, Zhou SF, Xiang DX, Wang T, Li Y, Lim LY,
Kong LX, Li LH, Duan W. RNA aptamers targeting cancer
stem cell marker CD133. Cancer Letters. 2013; 330:84-95.
Deng JL, Wang L, Chen HM, Li L, Ma YM, Ni J, Li Y. The
role of tumour-associated MUC1 in epithelial ovarian
cancer metastasis and progression. Cancer and Metastasis
Reviews. 2013; 32:535-551.
with activation of the PI3K/Akt/mTOR pathway in prostate
cancer radioresistance. Cell Death and Disease. 2013;
4:e875.
Krishnan, S. and Maclean J (2013). Practice of
laryngectomy rehabilitation interventions: a perspective
from Australia. Current Opinion in Otolaryngology and
Head and Neck Surgery 21(3):224-229.
Other Published Material
You J, Cozzi PJ, Fitzgerald A, Walsh B, Russell PJ, Willcox
M, Graham P and Li Y. Prostate cancer biomarkers and
the emerging proteomic techniques used in biomarker
research. Horizons in Cancer Research, edited by Hiroto S.
Watanabe. Nova Science Publishers, Inc. USA. 2012;47:136.
Perry, A. and Maclean, J. (2012) Rehabilitation after
Treatment for Recurrent Head and Neck Cancer. In H.
Mehanna and K. Ang (Eds), Head and Neck Cancer
Recurrence: Evidence-based, Multidisciplinary
Management (pp. 253-259). Germany: Thieme.
You J, Willcox M, Madigan MC, Wasinger V, Schiller B,
Walsh B, Graham P, Kearsley J and Li Y. Tear as a source
of protein biomarkers for human disease diagnosis and
prognosis. Advancers in Clinical Chemistry, edited by Greg
Makowski, Elsevier. 2013; 62:151-187.
Maclean, J – Co-Author - ACI - Care of adult patients in
acute care facilities with a tracheostomy – Clinical Practice
Guideline 2013.
Maclean, J – Co-Author - Speech Pathology Australia Clinical Guideline – Laryngectomy Management 2012.
Presentations at Scientific Meetings and
Conferences
2012 - International
Xiao W, Graham P, Power C, Dong QH, Cozzi PJ, Kearsley
J and Li Y (2012). The histone deacetylase inhibitor
LBH589 combined with radiation is an effective regimen
for prostate cancer. Advances in prostate cancer researchAACR special conference, 6-9 Feb. Orlando USA.
Ni J, Cozzi P, Hao JL, Beretov J, Chang L, Duan W,
Shigdar S, Delprado W, Graham P, Bucci J, Kearsley J
and Li Y. Epithelial cell adhesion molecule (CD326) is
associated with prostate cancer metastasis and chemo-/
radioresistance via PI3K/Akt/mTOR signaling pathway.
International Journal of Biochemical Cell Biology. 2013;
45:2736-2748.
Wang L, Chen HM, Liu FH, Beretov J, Hao JL, Chao HT,
Perkins AC, Kearsley J and Li Y (2012). Studies of the effect
of anti-MUC1 monoclonal antibody (C595) with docetaxel
in in vitro epithelial ovarian cancer cells and an in vivo
animal model. The 3rd International Ovarian Cancer
Symposium: Prevention, Detection and Treatment of the
Disease and Its recurrence, 10-11 May. Pittsburgh, PA,
USA.
Chang L, Graham P, Hao JL, Ni J, Bucci J, Cozzi P,
Kearsley J and Li Y. Acquisition of epithelial-mesenchymal
transition and cancer stem cell phenotypes is associated
Li Y, Chao HT, Wang L, Hao JL, Ni J, Graham P, Kearsley
J (2012). Combination of low dose histone deacetylase
inhibitor, LBH589, with docetaxel is an effective option for
78
epithelial ovarian cancer treatment. The 3rd International
Ovarian Cancer Symposium: Prevention, Detection and
Treatment of the Disease and Its recurrence, 10-11 May,
Pittsburgh, PA, USA.
in vitro and in vivo prostate cancer metastasis and
chemoresistance. 14th International Biennial Congress of
the Metastasis Research Society, 2-5 September, Brisbane,
Australia.
Beretov J, Wasinger V, Graham P, Kearsley J and Li Y
(2012). Identification of novel urine biomarkers from
metastatic breast cancer patients using proteomic
approaches. Asia Oceania Human Proteome Organization
(AOHUPO) 6th Congress, 5-7, Beijing, China.
Chang L, Peter G, Hao JL, Ni J, Bucci J, Cozzi P, Kearsley
J and Li Y (2012). Developing radiation resistant prostate
cancer cell lines with epithelial mesenchymal transition
(EMT) characteristic for prostate cancer treatment. The St
George & Sutherland Medical Research Symposium, 11
Oct, 2012, Sydney, Australia.
Beretov J, Wasinger V, Graham P, Kearsley J and Li Y
(2012). Proteomic identification of novel urine biomarkersfor the early detection of breast cancer. HUPO 11th Annual
World Congress, September 9-13, Boston, USA.
Maclean, J., Szczesniak, M., Zhang, T., Graham, P., and
Cook, I. (2012). Dysphagia is a Prevalent and Under
Recognized Complication of Head and Neck Radiotherapy.
Paper presented at. Dysphagia Research Society, Toronto,
USA, March 2012.
Maclean, J., Szczesniak, M., Pramsothy, S., Zhang, T.,
Graham, P., & Cook, I. (2012). Esophageal Dysmotility in
Laryngectomy Patients: An Unrecognized Association?.
Paper presented at Dysphagia Research Society, Toronto,
USA, March 2012.
Kearsley, J. Analysis of student reflections: “It is not
a disease we treat but a person”. Paper presented at
the Palais des Congrès,19th International Congress on
Palliative Care, Montreal, Canada. October.
Li, Y., Chao, H., Wang, L., Hao, J., Ni, J., Graham, P. and
Kearsley, J. (2012). Combination of low dose histone
deacetylase inhibitor, LBH589, with docetaxel is an
effective option for epithelial ovarian cancer treatment.
Paper presented at the The 3rd International Ovarian
Cancer Symposium: Prevention, Detection and Treatment
of the Disease and Its recurrence. Pittsburgh, PA, USA,
May.
2012 - National
Molloy, T., Pajic, M., Holzhauser, S., Graham, P., Millar,
E., & Sutherland, R. (2012). Identification of miRNAs
as potential mediators of radiotherapy resistance in
breast cancer. Paper presented at the 24th Lorne Breast
Conference. Victoria.
Ni J, Cozzi P, Beretov J, Duan W, Delprado W, Graham P,
Kearsley J and Li Y (2012). Over-expression of EpCAM
(CD326) and CD44 variants in human prostate cancer cells
are potential therapeutic targets for targeted therapy.
13th Australasian Prostate Cancer Conference, 31 July.
Melbourne.
Li Y, Hao JL, Madigan MC, Khatri A, Power CA, Hung
TT, Beretov J, Xiao W, Cozzi PJ, Kearsley J (2012).
Over-expression of either CD44 or CD147 modulates
Ni J, Cozzi P, Hao JL, Beretov J, Chang L, Duan W,
Delprado W, Graham P, Bucci J, Kearsley J and Li
Y (2012). EpCAM (CD326) and CD44 variants are
biomarkers associated with prostate cancer metastasis
and progression. The St George & Sutherland Medical
Research Symposium, 11 October, Sydney.
Chang L, Graham P, Hao JL, Ni J, Bucci J, Cozzi P, Kearsley
J and Li Y (2012). Epithelial mesenchymal transition (EMT)
is involved in the prostate cancer radiation resistance.
IPOS 14th world congress and COSA’s 39th annual
scientific meeting, 13-15 November, Brisbane.
Beretov J, Wasinger V, Graham P, Kearsley J and Li Y
(2012). Discovering Urine Protein Biomarkers in Breast
Cancer using Proteomic Technology. The St George &
Sutherland Medical Research Symposium, 11 October,
Sydney.
Beretov J, Wasinger V, Peter Scwartz, Graham P, Kearsley
J and Li Y (2012). Discovering Urine Protein Biomarkers in
Breast Cancer using Proteomic Technology. “Proteomics
and Beyond” Symposium, Macquarie University, 7th
November, Sydney.
Ni J, Cozzi P, Hao JL, Beretov J, Chang L, Duan W,
Delprado W, Graham P, Bucci J, Kearsley J and Li Y
(2012). EpCAM (CD326) is a biomarkers associated with
prostate cancer metastasis and progression. AACBS
annual scientific meeting, Sydney, 16 December 2012.
Chang L, Graham P, Hao JL, Ni J, Bucci J, Cozzi P, Kearsley
J and Li Y (2012). Acquisition of radioresistance and EMT/
CSC phenotypes is linked with activation of the PI3K/Akt/
mTOR pathway in prostate cancer cells. AACBS annual
scientific meeting, Sydney, Australia, 16 December 2012.
Maclean J, Szczesniak M, Paramsothy S, Zhang T, Graham,
P, Cook IJ. Australian and New Zealand Head and Neck
Cancer Society, Oesophageal dysmotility in laryngectomy
patients: An unrecognized association, Brisbane, October,
2012,
Maclean, J.C., Szczesniak M, Graham, P, Cook IJ.
Australian and New Zealand Head and Neck Cancer
Society, Brisbane, October, 2012, Long-term dysphagia
following Radiotherapy.
79
Maclean, J.C., Australian and New Zealand Head and
Neck Cancer Society, Brisbane, October, 2012, invited
panellist IFHNOS Session 3: Multidisciplinary Therapy.
2013 - International
Li Y, Wang L, Chao H, Hao J, Ni J, Chang L, Deng J,
Graham P, Kearsley J (2013). Combining low dose LBH589
with docetaxel increases apoptosis in epithelial ovarian
cancer cells via PI3K/Akt /mTOR signalling pathway. IGCS,
Bali, Indonesia, 11-13 April 2013.
Chang L, Wasinger V, Graham P, Hao JL, Ni J, Beretov J,
Bucci J, Cozzi P, Kearsley J and Li Y (2013). Identification of
novel biomarkers for prostate cancer radioresistance using
the label-free LC-MS/MS approach. HUPO 12th Annual
World Congress, Yokohama, Japan, 14-18 September
2013.
Beretov J, Wasinger V, Schwartz P, Graham P, Millar E,
Kearsley J and Li Y (2013). Proteomic investigation of
breast cancer biomarkers using human plasma and serum
samples. HUPO 12th Annual World Congress, Yokohama,
Japan, 14-18 September 2013.
Chang L, Graham P, Hao JL, Ni J, Bucci J, Cozzi P, Kearsley
J and Li Y (2013). PI3K/Akt/mTOR dual inhibitors have
obvious advantages over single inhibitors in overcoming
prostate cancer radioresistance. AACR- Molecular Targets
and Cancer Therapeutics, Boston, MA, USA, 19-23 Oct
2013.
Li Y, Chang L, Graham P, Hao JL, Ni J, Bucci J, Cozzi
P, Kearsley J (2013). Prostate cancer radioresistance is
associated with acquisition of epithelial-mesenchymal
transition and cancer stem cell phenotypes via activation
of the PI3K/Akt/mTOR pathway. The 6th EMT International
Association (TEMTIA) Conference-Alicante, Spain, 13-16
Nov 2013.
Maclean, J.C., Ward EC., Findlay M, Rees G Dysphagia
and nutritional management in Australian and New
Zealand head and neck cancer centres , Dysphagia
Research Society, Seattle, USA, March.
2013 - National
Ni J, Cozzi P, Hao JL, Beretov J, Chang L, Duan W,
Delprado W, Graham P, Bucci J, Kearsley J and Li Y
(2013). CD44 variant 6 is a biomarkers associated with
prostate cancer metastasis and progression. The Lowy
Cancer Symposium. UNSW, Sydney,May.
Chang L, Graham P, Hao JL, Ni J, Bucci J, Cozzi P, Kearsley
J and Li Y (2013). Acquisition of epithelial-mesenchymal
transition and cancer stem cell phenotypes is associated
with activation of the PI3K/Akt/mTOR pathway in prostate
cancer radioresistance. Prostate Cancer World Congress,
Melbourne, 6-10 August.
80
Maclean, J.C., Szczesniak M, Graham, P, Cook IJ.
Australian and New Zealand Head and Neck Cancer
Society, Melbourne, September, 2013, Cricopharyngeal
dysfunction – assessment and treatment.
Community Engagement
A/Prof Yong Li
Associate Editor of World Journal of Cancer Research,
USA (2012).
Member, Epithelial-Mesenchymal Transition International
Association (TEMTIA) 2013.
Vice-president of the Australian Chinese Association
of Chinese Biomedical Scientists (AACBS) 2013~ and
responsible for organizing the Annual meeting and
scientific meeting.
Dr Julia Maclean
Executive member, Australian and New Zealand Head and
Neck Cancer Research Foundation
Treasurer, Executive Australian and New Zealand Head and
Neck Cancer Society.
SURGERY
PERIOPERATIVE
& ANAESTHETIC
SERVICES
Anaesthesia
St George Hospital
>
83
Cardiothoracic Surgery
>
85
Liver and
Peritonectomy Surgery
>
90
Orthopaedic Surgery
>
96
Trauma
>
104
Vascular Surgery
>
108
>
Department of Anaesthesia
St George Hospital
Head of Department
Richard Morris MBBS FANZCA
Senior Medical- Staff Specialists
Maggie Bailey BMBS FANZCA Lecturer Conjoint UNSW
Chimene Bhar MBBS FRCA
Neil Bradburn MBBS FANZCA Lecturer Conjoint UNSW
Peter Cox MBBS FANZCA
Marie Dreux BMBS FANZCA Lecturer Conjoint UNSW
Anthony Lewis PhD MB BCh FRCA FANZCA
Liz Mackson MBBS FANZCA
Andrew Mcdonald MBBS FANZCA
Peter Nay MBBS FRCA FANZCA
She-yin Ng MBBS FANZCA
Pauline Paton MBBS FANZCA
Sharon Tivey MBBS FANZCA Lecturer Conjoint UNSW
Anica Vasic MBBS FANZCA
Visiting Medical Officers
Andrew Armstrong MBBS FANZCA Lecturer Conjoint
UNSW
Erez Ben-Menachem MBBS FANZCA
Philip Black BMBS FANZCA
Peter Brennan MBBS FANZCA
Colleen Bruce MBBS FANZCA
Angela Brothers MBBS FANZCA
Matthew Bruce MBBS FANZCA
Matthew Chiew MBBS FANZCA
Matthew Coady MBBS FANZCA
Michael Cooper BMBS FANZCA
Daniel Cox BMBS FANZCA
Vincent DaSilva MBBS FANZCA
Cyrus De Souza MBBS FANZCA
Tamara Eichel MBBS FANZCA
Robert Fabina MBBS FANZCA
Alex Fang MBBS FANZCA
Salwan Fransi MBBS FANZCA Lecturer Conjoint UNSW
David Goodie MBBS FANZCA
Rajiv Gupta MBBS FANZCA
Andrew Guy MBBS FANZCA
Simon Harper MBBS FANZCA
Drew Heffernan MBBS FANZCA
Michael Henderson MBBS FANZCA
Robert Higgs MBBS FANZCA
Mark Higney MB ChB FRCA FANZCA
Andrew Howard MBBS FANZCA
Cameron Hunt MBBS FANZCA
Michael Kerr MBBS FANZCA
Andrew Kennedy MBBS FANZCA
Gerhard Labuschage MB ChB MMed(Anest) FCA(SA)
FANZCA
Harold Lam MBBS FANZCA
Mike Lambros MBBS FANZCA
Ben Ma MBBS FANZCA
Bobby Manasiev MBBS FANZCA
Joanne Momsen MBBS FANZCA
Gisele Mouret MBBS FANZCA
Jodi Murphy MBBS FANZCA
Manu Narayanaswamy MBBS FANZCA
Neeraj Pal MBBS FANZCA
Pamela Salerno MBBS FANZCA
Marianne Sidhom MBBS FANZCA
Kate Smyth MBBS FANZCA
Vincent Sperando MBBS FANZCA
Mark Steward MBBS FANZCA
Abhijeet Tandel MBBS FANZCA
Sue-Ann Wan MBBS FANZCA
Helen Zois MBBS FANZCA
Research Projects in Progress
Enhanced oral intake prior to colonoscopy, G
Labuschagne, M Kerr, T Holliday, R Morris.
Comparison of Prothrombinex vs Fresh Frozen Plasma
during Peritonectomy Surgery A Lewis, S Ho, D Morris, W
Liau
Original Peer-Reviewed Publications
Howe PW, Cooper MG. Blood loss and replacement for
spring cranioplasty in Australia – a prospective national
audit. Anaesthesia and Intensive Care 2012; 40: 107-113.
Santoro AS, Cooper MG, Cheng A. Failed intubation and
failed oxygenation in a child. Anaesthesia & Intensive Care
2012:40: 1056-1058.
Liao AY, Levin B, Daniel M, Chan L, Cooper MG, Birman
CS. Emergency EXIT: an urgent ex utero intrapartum
trachestomy for giant fetal neck mass. Aust NZ J Surgery
2013; 83: 684-685.
Chatterjee DJ, Reid C, Lewis A. A potential technique for
flexible scope-assisted intubation using an Ambu aScope
2TM inserted via a supraglottic airway device. Anaesthia
and Intensive Care. 2012 July 40(4):724.
83
Reid C, Lewis A, Habig K, Burns B, Billson F, Kunkel S, Fisk
W. Sustained life-like waveform capnography after human
cadaveric tracheal intubation. Emergency Med J. 2013 Oct
8. doi: 10.1136/emermed-2013-203105. [Epub ahead of
print].
Presentations at Scientific Meetings and
Conferences
2012 - International
Cooper MG. Pulse oximetry – Lifebox and a standard of
care for anaesthesia and surgery in Papua New Guinea.
Papua New Guinea Medical Symposium, Port Moresby,
September 2012.
2013 - International
Lewis, A, Airway Management in Prehospital and Retrieval
Medicine. Society of Anaesthetists of Wales Autumn
Meeting. LLandrindod Wells, Wales, 7th November 2013
Lewis, A Simulation using Mobile Technology. Society
of Anaesthetists of Wales Autumn Meeting. LLandrindod
Wells, Wales, 7th November 2013
Lewis A, Richmond C. Sim Training. Cost effective ways
to Train in your department. Developing Emergency
Medicine, Havana, Cuba. 17th September 2013.
Lewis A, Richmond C. Train the Trainer Sim Training.
Developing Emergency Medicine, Havana, Cuba. 17th
September 2013.
2013 - National
ANZAC, Gallipoli, WW1. 8th International Symposium on
the History of Anaesthesia, Sydney, Jan 2013.
Graves M, Cooper MG. Anaesthesia at a Casualty Clearing
Station: Review of an Australian Anaesthetists role in the
Great War. 8th International Symposium on the History of
Anaesthesia, Sydney, Jan 2013.
Cooper MG (speaker and chair). The challenges of
paediatric anaesthesia in the developing world. Society
of Paediatric Anaesthetists of Australia & New Zealand
Annual Meeting, October 2013, Sydney.
84
Cooper MG. Technology vs Tradition: How to get into
print. NSW Anaesthetic Continuing Education meeting,
Australian & New Zealand College of Anaesthetists,
Sydney, Jun 15, 2013.
Howard, A. Peri-operative Arrhythmias at Technology
Meets Tradition, ANZCA and ASA 79th Continuing
Education Seminar, Sydney, 15th June 2013.
>
Department of Cardiothoracic Surgery
Head of Department
Dr Gary Fermanis MBBS (Hons) FRACS
Visiting Medical Officers
Dr Con Manganas MBBS MS (NSW) FRACS
Dr Matthew Horton MBBS FRACS
Dr Sheen Peeceeyen MCh
Senior Research
Dr Christopher Cao MBBS, BSc (Med)
Nursing Research
Patricia Newbon, RN
Research Projects in Progress
Review of patients who have undergone pneumonectomy
at St George Hospital 1992 - 2014, with a view to long
term outcomes. Dr A Kashani (Thesis).
Original Peer-Reviewed Publications
Cao C, Tian D, Manganas C, Matthews P, Yan TD.
Systematic review of trimodality therapy for patients with
malignant pleural mesothelioma. Ann Cardiothorac Surg.
2012 Nov;1(4):428-37.
Cao C, Indraratna SAP, Manganas C, Bannon P, Black
D, Yan T. D. Systematic Review and Meta-analysis of
Transcatheter Aortic Valve Implantation versus Surgical
Aortic Valve Replacement for Patients with Severe Aortic
Stenosis. Ann Cardiothorac Surg. 2012 Nov 15. DOI:
10.3978/j.issn.2225-319X.2012.11.09
Cao C, Manganas C, Ang SC, Peeceeyen S, Yan TD.
Video-assisted thoracic surgery versus open thoracotomy
for non-small cell lung cancer: a meta-analysis of
propensity score-matched patients. Interact Cardiovasc
Thorac Surg. 2013 Mar 16(3) 244-9.
Cao C, Manganas C, Indraratna P, Ang S, Bannon P, Yan
T. Cost-effectiveness of TAVI versus surgery for high-risk
patients with aortic stenosis. J Am Coll Cardiol. 2013 Apr
23;61(16):1747-8.
controlled trials. J Thorac Cardiovasc Surg. 2013 Aug
146(2) 255-61.
Cao C, Manganas C, Ang S, Yan, TD. A systematic review
and meta-analysis on pulmonary resections by robotic
video-assisted thoracic surgery. Annals of Cardiothoracic
Surgery. 2012 May. 1 (1): 3-10.
Cao C, Manganas C, Ang S, Yan, TD. A meta-analysis
of unmatched and matched patients comparing videoassisted thoracoscopic lobectomy and conventional open
lobectomy. Annals of Cardiothoracic Surgery. 2012 May. 1
(1): 16-23.
Cao C, Manganas C, Bannon P, Vallely M, Yan TD. Drugeluting stents versus coronary artery bypass graft surgery
in left main coronary artery disease: A meta-analysis of
early outcomes from randomized and nonrandomized
studies. J Thorac Cardiovasc Surg. 2013 Mar 145(3) 73847.
Farkouh ME, Domanski M, Sleeper LA, Siami FS,
Dangas G, Mack M, Yang M, Cohen DJ, Rosenberg Y,
Solomon SD, Desai AS, Gersh BJ, Magnuson EA, Lansky
A, Boineau R, Weinberger J, Ramanathan K, Sousa
JE, Rankin J, Bhargava B, Buse J, Hueb W, Smith CR,
Muratov V, Bansilal S, King S 3rd, Bertrand M, Fuster V;
FREEDOM Trial Investigators. Strategies for multivessel
revascularization in patients with diabetes. N Engl J Med.
2012 Dec 20;367(25):2375-84.
Other Published Material
Cao C, Manganas C, Byrom M, Yan, T.D. Re: Radial
artery or saphenous vein, a graft of second choice in
coronary artery bypass surgery. J Thorac Cardiovasc Surg
Apr;145(4):1147-8.
Cao C, Manganas C, Indraratna P, Ang S, Yan T. Re:
Transcatheter aortic valve implantation (TAVI): risky and
costly. BMJ 2012;345 e4710.
Cao C, Manganas C, Byrom M, Yan TD. Reply to the
editor. J Thorac Cardiovasc Surg. 2013 Apr;145(4):1147-8.
Cao C, Manganas C, Horton M, Bannon P, MunkholmLarsen S, Ang SC, Yan TD. Angiographic outcomes of
radial artery versus saphenous vein in coronary artery
bypass graft surgery: A meta-analysis of randomized
85
Presentations at Scientific Meetings and
Conferences
All presentations are by Dr Christopher Cao.
The 7th China Lung Cancer Minimally Invasive Therapy
Forum/The 4th Asia-Pacific minimally Invasive Thoracic
Surgery Conference (Guangzhou, China; December 2013)
1. XSOLA Study
2. Meta-analysis of Segmentectomy vs Lobectomy for
Patients with NSCLC
Meta-analysis of Propensity Score Matched Patients
7. Level 1A Evidence on Angiographic Outcomes of
Radial Artery versus Saphenous Vein in Coronary
Artery Bypass Graft Surgery
8. A Systematic Review and Meta-analysis on Pulmonary
Resections by Robotic Video-assisted Thoracic
Surgery
9. Cross-sectional Study on Lobectomy Approach
(X-SOLA)
15th World Conference on Lung Cancer (Sydney,
Australia; October 2013)
10. Should Clopidogrel be Discontinued Prior to Coronary
Artery Bypass Graft Surgery for Patients with Acute
Coronary Syndrome?
1. Systematic Review of Pleurectomy in the Treatment of
Malignant Pleural Mesothelioma
11. Systematic Review of Trimodality Therapy for Patients
with Malignant Pleural Mesothelioma
2. A Meta-analysis of Extended Pleurectomy/
Decortication versus Extrapleural Pneumonectomy in
the Treatment of Malignant Pleural Mesothelioma
EuroPCRMeeting (Paris, France; May 2013):
3. Video-assisted thoracic surgery versus open
thoracotomy for non-small cell lung cancer - A metaanalysis of propensity score matched patients
4. A Systematic Review and Meta-analysis on Pulmonary
Resections by Robotic Video-assisted Thoracic
Surgery
5. Cross-sectional Study on Lobectomy Approach
(X-SOLA)
6. Video-assisted Thoracoscopic Surgery at 20 Years: A
Consensus Statement
Cardiac Society of Australia and New Zealand Annual
Scientific Meeting (Darwin, Australia; August 2013):
1. A Systematic Review and Meta-analysis of
Transcatheter Aortic Valve Implantation versus
Surgical Aortic Valve Replacement for Patients with
Severe Aortic Stenosis (Baxter Young Achiever Award
Winner)
2. A Systematic Review of the Cost-effectiveness of
Transcatheter Aortic Valve Implantation
3. A Meta-analysis of Drug-eluting Stents versus
Coronary Artery Bypass Graft Surgery in Left Main
Coronary Artery Disease
4. Systematic Review of Pleurectomy in the Treatment of
Malignant Pleural Mesothelioma
5. Video-assisted Thoracoscopic Surgery at 20 Years: A
Consensus Statement
6. Video-assisted Thoracic Surgery versus Open
Thoracotomy for Non-small Cell Lung Cancer – A
86
1. TAVI versus Surgical Aortic Valve Replacement for
Patients with Severe Aortic Stenosis
2. Cost Analysis of TAVI – Can We Afford It?
20th Anniversary of VATS Lobectomy Consensus Meeting
(Edinburgh, UK; November 2012):
1. VATS Lobectomy versus Open thoracotomy – A
Systematic Review and Meta-analysis Propensity Score
Matched Patients
2. Cross-sectional Study on Lobectomy Approach
(X-SOLA)
Cardiac Society of Australia and New Zealand Annual
Scientific Meeting (Brisbane, Australia; August 2012):
1. Drug-Eluting Stents versus Coronary Artery Bypass
Graft Surgery in Left Main Coronary Artery Disease - A
Meta-analysis of Randomized and Nonrandomized
Studies
2. Current Level IA Evidence for Radial Artery versus
Saphenous Vein in Coronary Artery Graft Surgery – A
Systematic Review and Meta-analysis of Randomized
Controlled Trials
Royal Australasian College of Surgeons ASC (Kuala
Lumpur, Malaysia; May 2012):
1. Drug-Eluting Stents versus Coronary Artery Bypass
Graft Surgery in Left Main Coronary Artery Disease - A
Meta-analysis of Randomized and Nonrandomized
Studies
2. Current Level IA Evidence for Radial Artery versus
Saphenous Vein in Coronary Artery Graft Surgery – A
Systematic Review and Meta-analysis of Randomized
Controlled Trials
3. Meta-analysis of VATS versus Open Thoracotomy for
Early-Stage NSCLC
4. An Unusual Presentation of Recurrent Pneumonia
(e-Poster).
87
>
Department of Colorectal Surgery
Head of Department
Assoc Professor David Lubowski FRACS
Senior Medical
Professor Denis King OAM FRACS
Dr D Shevy Perera FRACS
Dr Steven Gan FRACS
Dr Daniel Kozman FRACS
Junior Medical
Dr Kim Phan-Thien FRACS Colorectal Fellow
Research Staff
Vicki Patton RN Bsc(Health) MN(Hons)
Original Peer-Reviewed Publications
2012
Lubowski DZ. Editorial. Colorectal surgery: rigour and
logic when treating pelvic floor disorders. Editorial;
ANZJS 2012; 82:383-384 .
Dinning PG, Hunt LM, Arkwright JW, Patton V, Szczesniak
MM, Wiklendt L,Davidson JB, Lubowski DZ, Cook
IJ. Pancolonic motor response to subsensory and
suprasensory sacral nerve stimulation in patients with slowtransit constipation. British J Surg 2012; 99(7):1002-1110.
2013
Wang S, McKay GD, Vonthethoff L, Lubowski DZ. Latent
schistosomiasis triggering mesenteric panniculitis. ANZJS
2013; 83:396-397.
Lubowski DZ. Editorial. Multidisciplinary team meetings.
ANZJ Surg 2013; 83:99-100.
Patton V, Wiklendt L, Arkwright JW, Lubowski DZ,
Dinning PG.The effect of sacral nerve stimulation on distal
colonic motility in patients with faecal incontinence. Br J
Surg 2013; 100(7); 959-968 Mar 27.
Diezmos EF, Sandow SL, Marcus L, Perera DS, Lubowski
DZ, King DW, Bertrand PP, Liu L Expression and
localization of pannexin-1 hemichannels in human colon
in health and disease. Neurogastroenterol Motil 2013; 25,
e395–e405.
88
Dinning P, Wiklendt L, Gibbins I, Patton V, Bampton P,
Lubowski DZ, Cook IJ, Arkwright J. Low-resolution colonic
manometry leads to a gross misinterpretation of the
frequency and polarity of propagating sequences: Initial
results from fibre-optic high-resolution manometry studies.
Neurogastroenterol Motil 2013; 25(10): e64.
Wang DH, Blenman N, Maunder S, Patton V, Arkwright J.
An optical fiber Bragg grating force sensor for monitoring
sub-bandage pressure during compression therapy. Optics
Express. 2013 Aug 26; 21(17):19799-807.
Presentations at Scientific Meetings and
Conferences
2012 - International
Sacral nerve stimulation workshop. Satellite Medtronic
meeting at ASCRS meeting, San Antonio, USA, 2-3 June
2012. “Sacral nerve stimulation: Clinical results” David Z.
Lubowski.
International College of Surgeons, 38th Biennial World
Congress, Brisbane, Australia, 7-9 November 2012.
“Sacral Nerve Stimulation for Faecal Incontinence” David
Z. Lubowski.
International Society University Colorectal Surgeons
ISUCRS Biennial Congress XXV Bolongna Italy 24
June 2012. “Clinical characteristics of patients treated
with sacral nerve stimulation for neurogenic faecal
incontinence.” V Patton.
2013 - International
American Society of Colon and Rectal Surgeons ASCRS
meeting, Phoenix, 1 May 2013. Panel Symposium
on “Worst Cases”. “Cases on: Anal fistula” David Z.
Lubowski
New Zealand Medical Association, GP CME Meeting,
Rotorua, 20 June 2013. “Management of anorectal
conditions” David Z. Lubowski.
Combined Spring Meeting of Colorectal Surgical Society
of Australia and NZ with Colon and Rectal Section of
RACS, Gold Coast 11-13 July 2013. “Management of
constipation / internal rectal prolapse.” David Z. Lubowski
2012 - National
UNSW Women’s Health and Research Institute of
Australia, Sydney 4 Feb 2012. “Proctalgia and Proctalgia
Fugax” David Z. Lubowski.
AGW , Adelaide, 18 October 2012. “Sacral nerve
stimulation for colonic motility disorders – is it prime
time?” David Z. Lubowski.
2013 - National
Annual Scientific Meeting Urogynaecological Society of
Australasia, Sydney, 16 March 2013. “Management of
post-defaecation soiling” David Z. Lubowski.
Pharmaceutical Society of Australia, Annual Meeting,
Sydney 2 June 2013. “Modern management of anorectal
conditions” David Z. Lubowski.
89
>
Department of Liver
and Peritonectomy Surgery
Head of Department
Research Projects in Progress
Professor David Lawson Morris
Pre-clinical evaluation of a novel nanoparticle, albuminbound albendazole in the treatment of chemo-resistant
ovarian cancer. Principal investigators: Mohammad
Pourgholami, Martina Stenzel, Lubna Noorani, Samina
Badar, David Morris.
Senior Medical
Dr Jai Seema Bagia
Junior Medical
Dr Nayef Alzahrani (Fellow – KSA Training Program)
Dr Saleh Alzahrani (Fellow – KSA Training Program)
Research Staff
Dr Mohammad Pourgholami, Principal Scientific Officer
MSc Pharmaceutical Sciences and PhD Pharmacology
Dr Jing Zhao, Hospital Scientist, M Med Sc
Dr Javed Akhter, Technical Officer, MSc, PhD
Dr Anahid Ehteda, Postdoc Research Fellow, UNSW BSc
(Microbiology); MSc (Microbiology), PhD
Dr Krishna Pillai, Research Assistant M Med Sc
(Pharmaceutical Drug Development),
Ms Stephanie Wai Ling Chu, Research Assistant, BSc (Hon);
MSc
Mrs Samina Badar, Research Assistant MSc
Mrs Farnaz Bahrami-Budlalu, Postgraduate Research
Student, Pharm D (Doctorate degree in Pharmacy),
Mrs Lubna Noorani, PhD student, UNSW M.Pharm.
Dr Afshin Amini, PhD student, MD
Dr Samar Masoumi Moghaddam, PhD student, MD
Dr Parvin Ataie-Kachoie, Research Officer, PharmAust Ltd
Pharm D (Doctorate degree in Pharmacy), PhD.
Research Grants
ARC project grant. Stenzel M, Morris DL, Pourgholami MH
Targeted therapies using Sprouty proteins: Synthetic
strategies to polyion complex micelles as smart nano-sized
drug carriers for proteins (390,000.00 over 3 years 20142017).
ARC project grant Stenzel M, Morris DL, Pourgholami MH
A platform for the efficient optimization of drug delivery
using cross-linked micelles and thioclick-chemistry toward
better anti-cancer treatment. ($450,000.00 over 3 years
2011-13).
90
Determination of the anticancer activity of monepantel
(AAD1566) in preclinical models of cancer. Principal
investigators: David Morris, Stephanie Chu, Samina Badar,
Parvin Ataie-Kachoie, Mohammad Pourgholami.
Evaluation of minocycline as a potential drug for the
treatment of cancer-induced angiogenesis, metastasis
and malignant ascites formation. Principal investigators:
Mohammad Pourgholami, Stephanie Chu, Samina Badar,
Parvin Ataie, David Morris.
Role of human Sprouty proteins ovarian and breast cancers
Principal investigators: Mohammad Pourgholami, Ahmed
Mekkawy, Samina Badar, Martina Stenzel, David Morris.
Development of mucolytic comprising of bromelain and
N-acetyl cysteine for the dissolution of mucin secreted
by pseudomyxoma peritonei, with enhanced efficacy by
addition of other agents. Principal investigators: J.Akhter,
K.Pillai, A Ekheda and DL. Morris.
Physio-chemical analysis of three grades of mucin
secreted by pseudomyxoma peritonei. Principal
investigators: K.Pillai, J.Akhter and DL. Morris.
Optimization of a mixture of bromelain and N-acetyl
cysteine for the treatment of malignant peritoneal
mesothelioma.
Principal investigators: K.Pillai, J.Akhter and DL. Morris.
Combination of bromelain, N-acetyl cysteine and aspirin
for the treatment of malignant peritoneal mesothelioma.
Principal investigators: K.Pillai, J.Akhter and DL. Morris.
Anti-Tumour and Chemosensitising effect of a
combination of bromelain + N-acetylcystein with cytotoxic
drugs on cancer cells. Principal investigators: L. Pillai,
J.Akhter and DL Morris.
Comparison of three thermal tumour ablative devices such
as monopolar, bipolar radiofrequency and microwave for
their efficacy in the absence and in the presence of heat
sink in perfused calf liver. Principal investigators: K.Pillai,
J.Akhter and DL. Morris.
Tumour cell release dynamics during thermal ablation of
liver tumours that involve the piercing of the surface of
tumours. Principal investigators: K.Pillai, J.Akhter and DL.
Morris.
Pharmacokinetics of Monepantel in Mice. Principal
investigators: A Ehteda, DL. Morris.
Combination therapy of Monepantel (AAD1566) with
commonly used chemotherapeutic agents. Principal
investigators: DL. Morris, MH Pourgholami, Parvin AtaieKachoie.
Cytotoxic and mucolytic effects of bromelain in
combination with N-acetylcysteine with potential value
in pseudomyxoma peritonei. Principal investigators: DL.
Morris, A Amini.
Evaluation of the expression of human Sprouty proteins
in epithelial ovarian cancer. Principal investigators: DL.
Morris, S Masoumi Moghaddam.
Original Peer-Reviewed Publications
2012
Amini, A., Masoumi moghaddam, S., Morris, D. L., &
Pourgholami, M. H. (2012). The Critical Role of Vascular
Endothelial GrowtFactor in Tumor Angiogenesis. Current
Cancer Drug Targets, 12(1), 23-43.
Carcinomatosis: Cytoreductive Surgery and HIPEC–Overview and Basics. Cancer Investigation, 30(3), 209-224.
Cao, C. Q., Yan, T. D., Deraco, M., Elias, D., Glehen, O.,
Levine, Sugarbaker, P. H. (2012). Importance of gender
in diffuse malignant peritoneal mesothelioma. Annals of
Oncology, 23 (6), 1494-1498.
Cao, C. Q., Yan, T. D., Morris, D. L., Van der speeten,
K., Laurberg, S., Glehen, O., Sugarbaker, P. H. (2012).
Prospective Registry On Mesothelioma Peritonei
Treatment (PROMPT): study design and rationale.]. Tumori,
98(1), 166-171.
Chua, T. C., & Morris, D. L. (2012). Colorectal Liver
Metastases with Extrahepatic Disease-A New Criteria for
Oncologic Resection? Journal of gastrointestinal cancer,
43(3), 502-504.
Chua, T. C., & Morris, D. L. (2012). Exploring the role of
resection of extrahepatic metastases from hepatocellular
carcinoma. Surgical Oncology, 21(2), 95-101.
Chua, T. C., & Morris, D. L. (2012). Resectable Colorectal
Liver Metastases: Optimal Sequencing of Chemotherapy.
Journal of gastrointestinal cancer, 43(3), 496-498.
Chua, T. C., & Morris, D. L. (2012). Therapeutic potential
of surgery for metastatic colorectal cancer. Scandinavian
Journal of Gastroenterology, 47(3), 258-268.
Amini, A., Masoumi moghaddam, S., Morris, D.
L., & Pourgholami, M. H. (2012). Utility of vascular
endothelial growth factor inhibitors in the treatment of
ovarian cancer: from concept to application. Journal of
Oncology, Volume 2012 (Article ID: 540791), 1-14. doi:
10.1155/2012/540791.
Chua, T. C., Al-Alem, I., Zhao, J., Glenn, D. W., Liauw,
W., & Morris, D. L. (2012). Radiofrequency ablation of
concomitant and recurrent pulmonary metastases after
surgery for colorectal liver metastases. Annals of Surgical
Oncology, 19(1), 75-81.
Bahrami, F., Morris, D. L., & Pourgholami, M. H. (2012).
Tetracyclines: drugs with huge therapeutic potential. MiniReviews in Medicinal Chemistry, 12(1), 44-52.
Chua, T. C., Chong, C. H., & Morris, D. L. (2012).
Peritoneal Mesothelioma. Current Status and Future
Directions. [10.1016/j.soc.2012.07.010]. Surgical Oncology
Clinics of North America, 21(4), 635-643.
Bester, L., Meteling, B., Pocock, N. A., Pavlakis, N., Chua,
T. C., Saxena, A., & Morris, D. L. (2012). Radioembolization
versus Standard Care of Hepatic Metastases: Comparative
Retrospective Cohort Study of Survival Outcomes and
Adverse Events in Salvage Patients. Journal of Vascular
and Interventional Radiology, 23(1), 96-105.
Brucher, B. L., Piso, P., Verwaal, V., Esquivel, J.,
Derraco, M., Yonemura, Y, Nissan, A. (2012). Peritoneal
Chua, T. C., Chong, C. H., Liauw, W. S., & Morris, D. L.
(2012). Approach to Rectal Cancer Surgery. International
Journal of Surgical Oncology, 2012 (Article ID: 247107),
1-9.
Chua, T. C., Chong, C. H., Liauw, W. S., Zhao, J., &
Morris, D. L. (2012). Inflammatory Markers in Blood and
Serum Tumor Markers Predict Survival in Patients With
Epithelial Appendiceal Neoplasms Undergoing Surgical
91
Cytoreduction and Intraperitoneal Chemotherapy. Annals
of Surgery, 256(2), 342-349.
efficacy in nude mice. Anticancer Research, 32(9), 36593666.
Chua, T. C., Esquivel, J., Pelz, J. O., & Morris, D. L. (2012).
Summary of current therapeutic options for peritoneal
metastases from colorectal cancer. Journal of Surgical
Oncology, 107(6), 566-573.
Khan, A. B., Al-Suhaibani, Y., Al-Mohaimeed, K., & Morris,
D. L. (2012). Application of Advanced Multimodality Care
to Pseudomyxoma Peritonei Patient: Report of First Patient
Treated at a Tertiary Center. Indian Journal of Surgical
Oncology, 1(3), 270-273.
Chua, T. C., Liauw, W. S., Chu, F., & Morris, D. L. (2012).
Summary outcomes of two-stage resection for advanced
colorectal liver metastases. [10.1002/jso.23170]. Journal of
Surgical Oncology, 107(2), 211-216.
Chua, T. C., Liauw, W. S., Chu, F., & Morris, D. L. (2012).
Viewing metastatic colorectal cancer as a curable chronic
disease. American Journal of Clinical Oncology - Cancer
Clinical Trials, 35(1), 77-80.
Chua, T. C., Liauw, W. S., Zhao, J., & Morris, D. L. (2012).
Comparative analysis of perioperative intraperitoneal
chemotherapy regimen in appendiceal and colorectal
peritoneal carcinomatosis. International Journal of Clinical
Oncology. June 18(3) 439-46.
Chua, T. C., Liauw, W., & Morris, D. L. (2012). Early
recurrence of pseudomyxoma peritonei following
treatment failure of cytoreductive surgery and
perioperative intraperitoneal chemotherapy is indicative
of a poor survival outcome. International Journal of
Colorectal Disease, 27(3), 381-389.
Chua, T. C., Moran, B. J., Sugarbaker, P. H., Levine,
E., Glehen, O., Gilly, F. N., Morris, D. L. (2012). Earlyand Long-Term Outcome Data of Patients With
Pseudomyxoma Peritonei From Appendiceal Origin
Treated by a Strategy of Cytoreductive Surgery and
Hyperthermic Intraperitoneal Chemotherapy. Journal of
Clinical Oncology, 30(20), 2449-2456.
Chua, T. C., Pelz, J. O., & Morris, D. L. (2012). Surgery for
colorectal peritoneal carcinomatosis. Scandinavian Journal
of Gastroenterology, 47(3), 277-285.
Chua, T. C., Saxena, A., Chu, F., & Morris, D. L. (2012).
Hepatic Resection for Transplantable Hepatocellular
Carcinoma for Patients Within Milan and UCSF Criteria.
American Journal of Clinical Oncology - Cancer Clinical
Trials, 35(2), 141-145.
Chua, T. C., Saxena, A., Liauw, W. S., Chu, F., & Morris,
D. L. (2012). Hepatectomy and resection of concomitant
extrahepatic disease for colorectal liver metastases - A
systematic review. European Journal of Cancer, 48(12),
1757-1765.
Ehteda, A., Galettis, P. T., Chu, S. L. W., Pillai, K. R., &
Morris, D. L. (2012). Complexation of albendazole with
hydroxypropyl-& #226;-cyclodextrin significantly improves
its pharmacokinetic profile, cell cytotoxicity and antitumor
92
Kim, Y., Liemmawal, E., Pourgholami, M. H., Morris, D.
L., & Stenzel, M. H. (2012). Comparison of shell-crosslinked micelles with soft and glassy cores as a drug
delivery vehicle for albendazole: Is there a difference in
performance? Macromolecules, 45(13), 5451-5462.
Kim, Y., Pourgholami, M. H., Morris, D. L., & Stenzel, M.
H. (2012). Effect of cross-linking on the performance of
micelles as drug delivery carriers: a cell uptake study.
Biomacromolecules, 13(3), 814-825.
Klaver, Y., Chua, T. C., De hingh, I., & Morris, D. L. (2012).
Outcomes of elderly patients undergoing cytoreductive
surgery and perioperative intraperitoneal chemotherapy
for colorectal cancer peritoneal carcinomatosis. Journal of
Surgical Oncology, 105(2), 113-118.
Masoumi moghaddam, S., Amini, A., Morris, D. L., &
Pourgholami, M. H. (2012). Significance of vascular
endothelial growth factor in growth and peritoneal
dissemination of ovarian cancer. Cancer and Metastasis
Reviews, 31(1-2), 143-162.
Mekkawy, A. H., Morris, D. L., & Pourgholami, M. H.
(2012). HAX1 Augments Cell Proliferation, Migration,
Adhesion, and Invasion Induced by Urokinase-Type
Plasminogen Activator Receptor. Journal of Oncology,
2012 (Article ID: 950749), 1-9.
Mirarabshahii, P., Pillai, K., Chua, T. C., Pourgholami, M.
H., & Morris, D. L. (2012). Diffuse malignant peritoneal
mesothelioma - An update on treatment. Cancer
Treatment Reviews, 38(6), 605-612.
Ng, K. M., Chua, T. C., Saxena, A., Zhao, J., Chu, F., &
Morris, D. L. (2012). Two decades of experience with
hepatic cryotherapy for advanced colorectal metastases.
Annals of Surgical Oncology, 19(4), 1276-1283.
Pillai, K., Akhter, J., Chua, T. C., & Morris, D. L. (2012).
Mucolysis by Ascorbic Acid and Hydrogen Peroxide on
Compact Mucin Secreted in Pseudomyxoma Peritonei.
[Journal of Surgical Research, 174(2), e69-e73.
Pillai, K., Akhter, J., Chua, T. C., & Morris, D. L. (2012).
Potential mucolytic agents for mucinous ascites from
pseudomyxoma peritonei. Investigational New Drugs,
30(5), 2080-2086.
Pourgholami, M. H., Mekkawy, A. H., Badar, S., & Morris,
D. L. (2012). Minocycline inhibits growth of epithelial
ovarian cancer. Gynecologic Oncology, 125(2), 433-440.
Journal of Clinical Oncology - Cancer Clinical Trials.
February, doi: 10.1097/COC.0b013e31827deea1.
Saxena, A., Chua, T. C., Chu, F., Al-Zahrani, A., & Morris,
D. L. (2012). Optimizing the surgical effort in patients with
advanced American Journal of Clinical Oncology - Cancer
Clinical Trials. Oct 35(5) 439-45.
Bester, L., Meteling, B., Pocock, N. A., Saxena, A., Chua,
T. C., & Morris, D. L. (2013). Radioembolisation with
Yttrium-90 microspheres: An effective treatment modality
for unresectable liver metastases. Journal of Medical
Imaging and Radiation Oncology, 57(1), 72-80.
Saxena, A., Chua, T. C., Perera, M., Chu, F., & Morris, D.
L. (2012). Surgical resection of hepatic metastases from
neuroendocrine neoplasms: A systematic review. Surgical
Oncology, 21(3), e131-e141.
Chan, D. L., Morris, D. L., & Chua, T. C. (2013).
Clinical efficacy and predictors of outcomes of repeat
hepatectomy for recurrent hepatocellular carcinoma – A
systematic review. Surgical Oncology, 22(2), e23-e30.
Saxena, A., Chua, T. C., Zhao, J., & Morris, D. L. (2012).
Liver-directed therapy for neuroendocrine neoplasm
hepatic metastasis prolongs survival following progression
after initial surgery. Journal of Surgical Oncology, 105(4),
342-350.
Chan, D. L., Morris, D. L., Chua, T. C., & Rao, A. (2013).
Intraperitoneal chemotherapy in ovarian cancer: A review
of tolerance and efficacy. Cancer Management and
Research, 4(1), 413-422.
Yang, T. X., Chua, T. C., & Morris, D. L. (2012).
Radioembolization and chemoembolization for
unresectable neuroendocrine liver metastases - A
systematic review. Surgical Oncology, 21(4), 299-308.
2013
Al-Alem, I., Pillai, K., Akhter, J., Chua, T. C., & Morris, D. L.
(2013). Heat Sink Phenomenon of Bipolar and Monopolar
Radiofrequency Ablation Observed Using Polypropylene
Tubes for Vessel Simulation. SurgicalInnovation. Oct 16
21(3) 269-76.
Amini, A., Ehteda, A., Masoumi, S., Moghaddam, S. M.,
Akhter, J., Pillai, K., & Morris, D. L. (2013). Cytotoxic effects
of bromelain in human gastrointestinal carcinoma cell
lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21).
OncoTargets and Therapy, 6, 403-409.
Ataie-Kachoie, P., Badar, S., Morris, D. L., & Pourgholami,
M. H. (2013). Minocycline Targets the NF- B Nexus through
Suppression of TGF- 1-TAK1-I B Signaling in Ovarian
Cancer. Molecular Cancer Research, 11(10), 1279-1291.
Ataie-kachoie, P., Morris, D. L., & Pourgholami, M. H.
(2013). Minocycline Suppresses Interleukine-6, Its Receptor
System and Signaling Pathways and Impairs Migration,
Invasion and Adhesion Capacity of Ovarian Cancer Cells:
In Vitro and In Vivo Studies. PLoS ONE, 8(4), Article
number 60817.
Ataie-Kachoie, P., Pourgholami, M. H., & Morris, D. L.
(2013). Inhibition of the IL-6 signaling pathway: A strategy
to combat chronic inflammatory diseases and cancer.
Cytokine & Growth Factor Reviews, 24(2), 163-173.
Bester, L., Feitelson, S., Milner, B., Chua, T. C., & Morris, D.
L. (2013). Impact of prior hepatectomy on the safety and
efficacy of radioembolization with Yttrium-90 microspheres
for patients with unresectable liver tumors. American
Chua, T. C., Quinn, L. E., Zhao, J., & Morris, D. L.
(2013). Iterative cytoreductive surgery and hyperthermic
intraperitoneal chemotherapy for recurrent peritoneal
metastases. Journal of Surgical Oncology, 108(2), 81-88.
Ehteda, A., Galettis, P., Pillai, K., & Morris, D. L. (2013).
Combination of Albendazole and 2-Methoxyestradiol
significantly improves the survival of HCT-116 tumorbearing nude mice. BMC Cancer, 13, Article number 86.
Kim, Y., Pourgholami, M. H., Morris, D. L., Lu, H., &
Stenzel, M. H. (2013). Effect of shell-crosslinking of
micelles on endocytosis and exocytosis: acceleration of
exocytosis by crosslinking. Biomaterials Science, 1, 265275.
Klaver, Y. L., Chua, T. C., Verwaal, V., De hingh, I. H., &
Morris, D. L. (2013). Secondary cytoreductive surgery and
peri-operative intraperitoneal chemotherapy for peritoneal
recurrence of colorectal and appendiceal peritoneal
carcinomatosis following prior primary cytoreduction.
Journal of Surgical Oncology, 107(6), 585-590.
Koh, J. L., Liauw, W., Chua, T., & Morris, D. L. (2013).
Carbohydrate antigen 19-9 (CA 19-9) is an independent
prognostic indicator in pseudomyxoma peritonei post
cytoreductive surgery and perioperative intraperitoneal
chemotherapy. J Gastrointest Oncol, 4(2), 173-181.
Moghaddam, S. M., Amini, A., Wei, A. Q., Pourgholami,
M. H., & Morris, D. L. (2013). Initial report on differential
expression of sprouty proteins 1 and 2 in human epithelial
ovarian cancer cell lines. Journal of Oncology, 2012,
Article ID 373826.
Morris, D. L. (2013). Peritonectomy HIPEC - Contemporary
results, indications. Chinese Journal of Cancer Research,
25(4), 373-374.
Pillai, K., Akhter, J., Chua, T. C., & Morris, D. L. (2013).
Anticancer Property of Bromelain With Therapeutic
93
Potential in Malignant Peritoneal Mesothelioma. Cancer
Investigation, 31(4), 241-250.
Pillai, K., Pourgholami, M. H., Chua, T. C., & Morris,
D. L. (2013). MUC1 as a Potential Target in Anticancer
Therapies. American Journal of Clinical Oncology, 1-1.
doi: 10.1097/COC.0b013e31828f5a07.
Pillai, K., Pourgholami, M. H., Chua, T. C., & Morris, D.
L. (2013). Ki67-BCL2 index in prognosis of malignant
peritoneal mesothelioma. American Journal of Cancer
Research, 3(4), 411-423.
Williams, B. H. M., Alzahrani, N. A., Chan, D. L., Chua, T.
C., & Morris, D. L. (2013). Repeat cytoreductive surgery
(CRS) for recurrent colorectal peritoneal metastases: Yes or
no? European Journal of Surgical Oncology (EJSO). doi:
10.1016/j.ejso.2013.10.022.
Yang, T. X., Billah, B., Morris, D. L., & Chua, T. C. (2013).
Palliative resection of the primary tumour in patients with
Stage IV colorectal cancer: systematic review and metaanalysis of the early outcome after laparoscopic and open
colectomy. Colorectal Disease, 15(8), e407-e419.
Yang, T. X., Morris, D. L., & Chua, T. C. S. (2013). Pelvic
exenteration for rectal cancer: A systematic review.
Diseases of the Colon and Rectum, 56(4), 519-531.
Pillai, K., Pourgholami, M. H., Chua, T. C., & Morris, D.
L. (2013). Does the expression of BCL2 have prognostic
significance in malignant peritoneal mesothelioma?
American Journal of Cancer Research, 3(3), 312-322.
Other Published Material
Pillai, K., Pourgholami, M. H., Chua, T. C., & Morris, D.
L. (2013). Oestrogen receptors are prognostic factors in
malignant peritoneal mesothelioma. Journal of Cancer
Research and Clinical Oncology, 139(6), 987-994.
Morris, DL (2013), Cytoreductive Surgery & Perioperative
Chemotherapy for Peritoneal Surface Malignancy.
Textbook and Video Atlas. PSOGI Group International.
Contributing Author.
Pillai, K., Pourgholami, M. H., Chua, T. C., & Morris, D. L.
(2013). MUC1 has prognostic significance in malignant
peritoneal mesothelioma. The International Journal of
Biological Markers, 28(3), 303-312.
Presentations at Scientific Meetings and
Conferences
Pourgholami, M. H., Ataie-Kachoie, P., Badar, S., & Morris,
D. L. (2013). Minocycline inhibits malignant ascites of
ovarian cancer through targeting multiple signaling
pathways. Gynecologic Oncology, 129(1), 113-119.
Akhter J, Pillai K, Al-Alem I, & Morris D L (2012).
Comparative study of radiofrequency ablation (RFA)
of a novel bipolar probe with a unipolar probe (in the
presence and absence of vessel simulation), using egg
white and ex-vivo liver model. Paper presented at The
Royal Australasian College of Surgeons Annual Scientific
Congress, Kuala Lumpur, Malaysia.
Saxena, A., Chua, T. C., Fransi, S., Liauw, W., & Morris,
D. L. (2013). Effectiveness of early and aggressive
administration of fresh frozen plasma to reduce massive
blood transfusion during cytoreductive surgery. J
Gastrointest Oncol, 4(1), 30-39.
Saxena, A., & Morris, D. L. (2013). Mortality and
Morbidity after Cytoreductive Surgery and Hyperthermic
Intraperitoneal Chemotherapy for Peritoneal
Carcinomatosis. Viszeralmedizin, 29(4), 6-6.
Ung, L., Chua, T. C., & Morris, D. L. (2013). Cure for
peritoneal metastases? An evidence-based review.. ANZ
Journal of Surgery, 83(11), 821-826.
Ung, L., Chua, T. C., & Morris, D. L. (2013). Peritoneal
metastases of lower gastrointestinal tract origin: a
comparative study of patient outcomes following
cytoreduction and intraperitoneal chemotherapy. Journal
of Cancer Research and Clinical Oncology, 139(11), 18991908.
Ung, L., Chua, T. C., & Morris, D. L. (2013). Cure for
peritoneal metastases? An evidence-based review. ANZ
Journal of Surgery, 83(11), 821-826.
2012 - International
Pillai K, Pourgholami MH, Akhter J, Chua TC, Morris DL
(2012). Ki67 is an important prognostic factor in malignant
peritoneal mesothelioma. Poster presented at the
Peritoneal Cancer Symposium, Munich, Germany.
2012 - National
Ataie-Kachoie P, Badar, S., Morris DL., Pourgholami
MH: Minocycline abolishes malignant ascites formation
and tumor growth through attenuation of tumor
growth factor-ß, vascular endothelial growth factor
and interleukin-6 pathways in an experimental model
of ovarian cancer. St. George and Sutherland Medical
Research Symposium, Sydney, October 2012.
Bahrami F, Pourgholami MH, Morris DL: Monepantel
suppress ovarian cancer cell proliferation by arresting
G0-G1 cell cycle and down regulating related cyclins and
Cdks proteins followed by inhibition of DNA incorporation.
St. George and Sutherland Medical Research Symposium
Sydney, October 2012.
Hossain L, Stenzel M, Pourgholami, MH, Morris DL:
Albumin Nanoparticles for Delivery of Albendazole in
94
Ovarian Cancer: Uptake of Albendazole loaded Albumin
Nanoparticles in Ovarian Cancer. Drug Delivery Australia,
Melbourne, November 2012.
Mekkawy AB, Pourgholami MH, Morris DL: Suppression
of growth factors-induced migration in human cells. St.
George and Sutherland Medical Research Symposium
Sydney, October 2012.
Pillai K, Akhter J, Chua TC, Morris DL. A revolutionary
method for the treatment of pseudomyxoma peritonei.
St. George and Sutherland Medical Research Symposium,
Sydney, October 2013.
Community Engagement
Pourgholami MH – Member of Scientific Committee St
George Medical Foundation.
2013 - International
Ataie-Kachoie, P., Morris, D. L., & Pourgholami, M. H.
(2013/04/15/). Minocycline abrogates IL-6 signaling and
inhibits migration, invasion and adhesion capacity of
ovarian cancer cells. Paper presented at the 104th Annual
Meeting of the American-Association-for-Cancer-Research
(AACR), Washington, DC.
2013 - National
Amini, A., Moghaddam, S. M., Ehteda, A., & Morris, D.
L. (2013). Cytotoxic effects of pineapple bromelain in
gastrointestinal carcinoma cell lines. Paper presented at
The 25th Lorne International Cancer Conference, Lorne,
Australia.
Ataie-Kachoie P, Badar S., Morris DL., Pourgholami MH.:
New implication for an old drug: minocycline as a potential
candidate for ovarian cancer. The 25th Lorne International
Cancer Conference, Lorne, Australia, February.
Ataie-Kachoie P, Badar, S., Morris DL., Pourgholami
MH.: Minocycline down-regulates NF-BB-regulated
cell proliferation, antiapoptotic and metastatic gene
products through the suppression of NF-BB activation in
ovarian cancer: in vitro and in vivo studies. St. George
and Sutherland Medical Research Symposium. Sydney,
October 2013.
Bahrami F, Morris DL, Pourgholami MH: Monepantel
suppress ovarian cancer cell proliferation by arresting cell
cycle at G1 and down regulating cyclins A, E, Cdk 2 and
4. The 25th Lorne International Cancer Conference, Lorne,
Australia, February 2013.
Bahrami F, Morris DL, Pourgholami MH: Monepantel
suppress ovarian cancer cell proliferation by arresting cell
cycle at G1 through AMPK/ ERK / p70S6k pathway and
down regulating cyclin D1, E, Cdk 4 and 2. St. George
and Sutherland Medical Research Symposium, Sydney,
October 2013.
Hossain L, Pourgholami MH, Liang R, Morris DL, Stenzel
M: Delivery of albendazole for the treatment of ovarian
cancer. Lowy Cancer Symposium, Sydney, May 2013.
Moghaddam, S. M., Amini, A., & Morris, D. L. (2013).
Human epithelial ovarian cancer cell lines differentially
express Sprouty proteins 1, 2 and 4. Paper presented at
the 25th Lorne International Cancer Conference, Lorne,
Australia.
95
>
Department of Orthopaedic Surgery and
Orthopaedic Research Institute
Head of Department
Original Peer-Reviewed Publications
Dr Robert Molnar
2012
Senior Medical
Xu Y,Bonar F,Murrell GA. (2012) Enhanced expression of
neuronal proteins in idiopathic frozen shoulder. J Shoulder
Elbow Surg 21 1391-7.
Professor George AC Murrell (Director, Orthopaedic
Research Institute)
Dr Ashish Diwan
Professor Ian Harris
Dr Hugh Jones
Professor Ron Sekel
Dr Wayne Viglione
Dr Zoltan Szomor
Dr S P Tan
Dr Michael Dixon
Dr Anthony Keeley
Junior Medical
Dr Adrian Hughes
Dr Edmund O’Leary
Dr Alice Chang
Research Staff
A/Prof Judie Walton
Dr Ai Qun Wei
Dr Patrick Lam
Dr Lijkele Beimers
Dr Aminudin Bin Mohammed Shamsudin
Dr P S Haen
Dr Justine Naylor
Dr Pooria Sarrami
Ms Helen Badge
Ms Deanne Jenkin
Ms Elizabeth Armstrong
Ms Deanne Jenkins
Mr David Mijalkov
Mr William du Moulin
Research Grants
HCF, Ian Harris, Improving services and outcomes for joint
replacement patients, $705,000; 2013-2015
Smith and Nephew (Investigator initiated), Dr Robert
Molnar, Radiostereometric Analysis (RSA) of The Genesis II
Minimally Invasive Surgery (MIS) Tibial Base Plate, $9000;
2008 - 2014)
96
Millar NL,Reilly JH,Kerr SC,Campbell AL,Little KJ,Leach
WJ,Rooney BP,Murrell GA,McInnes IB. (2012) Hypoxia: a
critical regulator of early human tendinopathy. Ann Rheum
Dis 71 (2) 302-10.
Walton JR,Murrell GAC. (2012) Effect of operative time on
outcomes of rotator cuff repair. Tech Shoulder Elbow Surg
13 (1) 23-7.
Walton JR,Murrell GA. (2012) Clinical tests diagnostic for
rotator cuff tear. Tech Shoulder Elbow Surg 13 (1) 17-22.
Shepherd H,Murrell GAC. (2012) Use of synthetic patches
as tendon substitutes in knotless arthroscopic repairs of
massive rotator cuff tears. Tech Shoulder Elbow Surg 13 (1)
32-5.
Le Lievre HMJ,Murrell GAC. (2012) Long-term outcomes
of arthroscopic capsular release for idiopathic adhesive
capsulitis. J Bone Joint Surg (Am) (94) 1208-16.
Peters K,McCallum S,Briggs L,Murrell GA. (2012) A
comparison of the outcomes of arthroscopic repair of
partial- versus full-thickness rotator cuff tears. J Bone Joint
Surg (Am) 94 1078-85.
Murrell GAC. (2012) Advances in rotator cuff repair undersurface repair. Tech Shoulder Elbow Surg 13 (1) 23-7.
Bokhari AR,Murrell GA. (2012) The role of nitric oxide in
tendon healing. J Shoulder Elbow Surg 21 (2) 238-44.
Kelly MJ,Andres B,Briggs L,Lam P,Ali R,Murrell GAC.
(2012) Ultrasound-guided placement of a localization
wire for arthroscopic treatment of calcific tendonitis. Tech
Shoulder Elbow Surg 13 (3) 134-7.
Millican J,Murrell GAC. (2012) Can handheld
dynamometers diagnose partial-thickness rotator cuff
tears? Shoulder and Elbow 4 (2) 100-5.
Wu XL,Briggs L,Murrell GA. (2012) Intraoperative
determinants of rotator cuff repair integrity: an analysis of
500 consecutive repairs. Am J Sports Med 40 (12) 2771-6.
Walton JR,Murrell GAC. (2012) A two-year clinical
outcomes study of 400 patients, comparing open surgery
and arthrosopic for rotator cuff repair. Bone Joint Res 1
210-17.
Millar NL,Murrell GA. (2012) Heat shock protein in
tendinopathy: novel molecular regulators. Mediators of
Inflammation (2012) (Article ID 436203) 1-7.
Kishen TJ, Lindstrom ST, Etherington G, and Diwan AD
(2012). Veillonella spondylodiscitis in a healthy 76-year-old
lady. Eur Spine J.; 21 Suppl 4: 413-7.
Mitchell SJ, Hilmer SN, Kirkpatrick CM, Hansen RD,
Williamson DA, Singh NA, Finnegan TP, Allen BJ, Diamond
TH, Diwan AD, Lloyd BD, Smith EU, and Fiatarone Singh
MA (2012). Estimation of lean body weight in older women
with hip fracture. J Nutr Health Aging.; 16: 188-92.
Molnar RB, Jenkin DE, Millar MJ, Campbell D,
Harris IA Feb, (2012). The Australian arthroplasty
thromboprophylaxis survey. J Arthroplasty, Feb 27(2):1739.
Hogg M, Molnar R, Shidiak L, Gillies M, May 1, (2012);.
Comparison of a 3-Hole Locking Plate With Angled
Screws to a Standard 4-Hole Hip Plate: A Finite Element
Study. Journal of Bone & Joint Surgery, British Volume,
94-B(SUPP XXIII):217.
Small T, Cairns P, Proctor J, Molnar R. A, May 1, (2012)
Pilot Study to Assess a Multimodal Approach to Short
Stay Arthoplasty. Journal of Bone & Joint Surgery, British
Volume;94-B(SUPP XXIII):44.
Molnar RB, Jenkin DE, Millar MJ, Campbell
D, Harris IA Feb (2012),The Australian
Arthroplasty Thromboprophylaxis survey, Journal
Arthroplasty;27(2):173-9.
Gnanenthiran SR, Adie S, Harris IA, Feb (2012),
Nonoperative versus Operative Treatment for
Thoracolumbar Burst Fractures Without Neurologic Deficit:
A Meta-analysis Clin Orthop Relat Res.;470(2):567-77.
Mitchell R, Watson WL, Curtis K, Harris I, McDougall P,
(2012) Jan, Difficulties in establishing long-term trauma
outcomes data collections. Could trauma outcomes
be routinely monitored in New South Wales, Australia:
piloting a 3 month follow-up? Injury.;43(1):96-102.
Adie S, Dao A, Harris I A, Naylor J M, Mittal R, (2012) Sep
Satisfaction with joint replacement in public vs private
hospitals: a cohort study, ANZ J Surg.;82(9): 616-624.
Arora M, Harris I A, McEvoy L, Mittal R, Naylor J M, (2012)
The effect of a single passive intervention to improve
patient satisfaction in an orthopaedic service Open Journal
of Orthopedics;2(2): 33.
Walton JR (2012) Evidence that ingested aluminum
additives contained in processed foods and alum-treated
drinking water are a major risk factor for Alzheimer’s
disease. Curr Inorg Chem 2, 19-33.
Walton JR (2012) Aluminum disruption of calcium
homeostasis and signal transduction resembles change
that occurs in aging and Alzheimer’s disease. J Alzheimers
Dis 29, 255-273.
Walton JR (2012) Cognitive deterioration and assocoiated
pathology induced by chronic low-level aluminum
ingestion in a translational rat model provides an
explanation of Alzheimer’s disease, tests for susceptibility
and avenues for treatment. Int J Alzheimers Dis, 91947,
17 pp doi:10.1155/2012/914947 (Open access).
2013
Tham ERX,Briggs L,Murrell GAC. (2013) Ultrasound
changes after rotator cuff repair - is supraspinatus tendon
thickness related to pain? J Shoulder Elbow Surg 22 (8)
e8-e15.
Millar NL,Murrell GA,McInnes IB. (2013) Alarmins in
tendinopathy: unravelling new mechanisms in a common
disease. Rheumatology (Oxford) 52 (5) 769-79.
Ronquillo J,Lam P,Murrell GAC. (2013) Arthroscopic ePTFE
patch repair for irrepairable rotator cuff tears. Part 1:
surgical technique and biomechanical comparison of two
suture techniques at the patch to tendon interface. Tech
Shoulder Elbow Surg 14 (2) 29-32.
Ronquillo JC,Lam P,Murrell GAC. (2013) Arthroscopic
ePTFE patch repair for irrepairable rotator cuff tears. Part
2: preliminary clinical results. Tech Shoulder Elbow Surg 14
(2) 33-41.
Ronquillo J,Briggs L,Lam P,Murrell GAC. (2013)
Morphological changes of synthetic (ePTFE) interpositional
patch repair for massive irrepairable rotator cuff tear; a
97
short term prospective clinical study. Tech Shoulder Elbow
Surg 14 (3) 73-80.
Journal of Biomimetics, Biomaterials & Tissue Engineering.
2013; 13: 97-118.
McFarland EG,Maffulli N,Del Buono A,Murrell
GAC,Garzon-Muvdi J,Petersen SA. (2013) Impingement
is not impingement: the case for calling it “Rotator Cuff
Disease”. Muscles Ligaments Tendons J 3 (3) 196-200.
Mathew J, Singh S, Garis S, and Diwan A (2013). Backing
up the stories: The psychological and social cost of low
back pain. Int J Spine Surgery. 2013; 7: 29-38.
Shepherd H,Lam P,Murrell GAC. (2013) Synthetic patch
rotator cuff repair- a 10-year follow-up. J Shoulder Elbow
Surg 6 (1) 35-9.
Murrell GA. (2013) Reply: measurement of posterior
capsule thickness. J Shoulder Elbow Surg 22 (8) e17.
Beimers L,Murrell GAC. (2013) Arthroscopic capsular
release for idiopathic adhesive capsulitis - surgical
technique. JBJS Essential Surgical Technique 3(1):e2.
Bhattacharjee S, Zhao Y, Hill JM, Culicchia F, Kruck TPA,
Percy ME, Pogue AI, Walton JR, Lukiw WJ (2013) Selective
accumulation of aluminum in cerebral arteries in Alzheimer’s
disease (AD). J Inorg Biochem 126, 35-37.
Diwan AD, Leong A, Appleyard R, Bhargav D, Fang
ZM, and Wei A (2013). Bone morphogenetic protein-7
accelerates fracture healing in osteoporotic rats. Indian J
Orthop. 2013; 47: 540-6.
Oliver RA, Yu Y, Yee G, Low AK, Diwan AD, and Walsh
WR (2013). Poor histological healing of a femoral fracture
following 12 months of oestrogen deficiency in rats.
Osteoporosis Int. 2013; 24: 2581-9.
Arora M, Chan EK, Gupta S, and Diwan AD (2013).
Polymethylmethacrylate bone cements and additives: A
review of the literature. World J Orthop. 2013; 4: 67-74.
Arora M, Diwan AD, and Harris IA (2013). Burnout in
orthopaedic surgeons: a review. ANZ J Surg. 2013; 83:
512-5.
Grigg M, Arora M, and Diwan AD (2013). Australian medical
students and their choice of surgery as a career: a review.
ANZ J Surg. 2013.
Grigg M, Diwan AD (2013). The painful back; elements of
current understanding. Karnataka Medical Journal. 46:3-6.
Arora M, Asha S, Chinnappa J, and Diwan AD (2013).
Burnout in emergency medicine physicians. Emerg Med
Australasia. 2013; 25: 491-495.
Chamoli U, Diwan AD, and Tsafnat N (2013). Pedicle screwbased posterior dynamic stabilizers for degenerative spine:
In vitro biomechanical testing and clinical outcomes. J
Biomed Mater Res A. Epub Date 2014/01/03
Zhou F, Wei A, and Diwan A (2013). An overview of
intervertebral disc degeneration and evaluation of the
chondrogenic and chemotactic potential of CDMP-2.
98
Arora M, Diwan AD, Harris IA (2013). Burnout in
orthopaedic surgeons: a review. ANZ J Surg. 2013 Jul;83(78):512-5.
Harris I A, Harris A M, Naylor J M, Adie S, Mittal R, Dao
A T (2013), Discordance Between Patient and Surgeon
Satisfaction After Total Joint Arthroplasty Journal of
Arthroplasty Volume 28, Issue 5, May 2013, Pages 722–727.
Buhagiar MA, Naylor J M, Harris I A, Xuan W, Kohler F,
Wright R J and Fortunato R (2013), Hospital Inpatient versus
Home-based rehabilitation after knee arthroplasty (The
HIHO study): study protocol for a randomized controlled
trial Trials 2013, 14:432.
Walton JR (2013) Aluminum’s involvement in the
progression of Alzheimer’s disease. J Alzheimers Dis 35,
7-43. (Open access)
Presentations at Scientific Meetings and
Conferences
2012- International
Murrell GAC, The 2nd International Symposium on
Musculoskeletal System and Pain, Sapporo, Japan.
Lecture: Advances in the diagnosis and management of
rotator cuff tears.
Murrell GAC, Funabashi Orthopaedic Sports Medicine
Center, Funabashi, Japan; Department of Orthopaedic
Surgery, Tohoku University School of Medicine, Sendai,
Japan. Lecture: Rotator cuff healing and repair.
Murrell G A C, 17th FINA World Sports Medicine Congress,
Istanbul, Turkey Lecture: Aetiology and Management of
Shoulder Problems in Swimming Workshop: Shoulder
assessment.
Harris I A, American Academy of Orthopaedic Surgeons
Annual Scientific Meeting, Tourniquet application only
during cement fixation in total knee arthroplasty: a doubleblind randomized controlled trial
Pulsed electromagnetic field stimulation for acute
tibia fractures: a multicenter double blind randomized
controlled trial.
Harris I A, AO Difficult Fracture Symposium – Korea, Timing
of surgery for hip fractures in the elderly
Bisphosphonates: weighing the risks and benefits.
Peters K,Briggs L,Murrell GAC. (2012). Ultrasound-guided
versus blind subacromial corticosteroid injection for
subacromial impingement. 2012 AAOS Annual Meeting,
February 7-11, San Francisco, CA. Poster P315.
shoulders. Australian Orthopaedic Association Annual
Scientific Meeting, October 7-11, (2012), Sydney.
Wu X,Briggs L,Murrell GAC. (2012) Intra-operative
determinants of rotator cuff repair integrity: an analysis
in 500 consecutive repairs. 2012 AAOS Annual Meeting,
February 7-11, San Francisco, CA. Paper 62.
Le Lievre HM,Murrell GAC. (2012) Long-term outcomes
of arthroscopic capsular release for frozen shoulder.
Australian Orthopaedic Association Annual Scientific
Meeting, October 7-11, Sydney.
Peters K,Murrell GAC. (2012) Permanent outperforms
biodegradable anchors for arthroscopic stabilization. 2012
AAOS Annual Meeting, February 7-11, San Francisco, CA.
Paper 201.
Peters K, Khoo J K, Wei A Q, Ronquillo J, Lam P, Murrell
GAC. (2012) Permanent outperforms biodegradable
anchors for arthroscopic shoulder stabilization. Australian
Orthopaedic Association Annual Scientific Meeting,
October 7-11, 2012, Sydney.
Dines J,Bedi A,Rodeo S,Murrell GAC. (2012) Biologic
Augmentation of Tendon-Bone Healing in the 21st
Century: Where are we now? Instructional Course Lecture
224. AAOS annual meeting, San Francisco, CA.
Wu X,Briggs L,Murrell GAC. (2012) Intra-operative
determinants of rotator cuff repair integrity: an analysis
in 500 consecutive repairs. AOSSM 2012 Specialty Day,
February 11, 2012, San Francisco, CA. Paper.
Peters K,Murrell GAC. (2012) Permanent outperforms
biodegradable anchors for arthroscopic stabilization. Open
Meeting of the American Shoulder and Elbow Surgeons,
Specialty Day, February 11, 2012, San Francisco, CA.
Paper.
Le Lievre HM,Murrell GAC. (2012) Excellent long-term
outcomes of arthroscopic capsular release for frozen
shoulder. Open Meeting of the American Shoulder and
Elbow Surgeons, Specialty Day, February 11, 2012, San
Francisco. Paper. (Finalist Neer Award).
Tham L,Briggs L,Murrell GAC. (2012) Ultrasound changes
after rotator cuff repair – is supraspinatus tendon thickness
related to pain? Orthopaedic Research Society 2012
Annual Meeting in San Francisco, California, February 4-7.
Poster.
Peters K,Murrell GAC. (2012) Permanent outperforms
biodegradable anchors for arthroscopic stabilization. 8th
Biennial AAOS/ASES Shoulder and Elbow Meeting May
3-5, 2012, Boca Raton Resort & Club, Boca Raton/Miami,
Florida. Paper.
Dines J,Bedi A,Rodeo S,Murrell GAC. (2012) Biologic
Augmentation of Tendon-Bone Healing in the 21st
Century: Where are we now? Instructional Course Lecture.
AAOS annual meeting, Chicago, IL.
2012 - National
Murrell GAC, Lecture: Ultrasound and advances in rotator
cuff repair. Australian Sonographers Association Annual
Meeting Canberra 2012.
Kurz AK, Kelly MJ, Briggs L,Murrell GAC (2012) Effect of
surgeon-sonographer intaraction on ultrasound diagnosis
of rotator cuff tears: a five-year cohort study in 775
Beimers L,Lam P,Murrell GAC. (2012) The effects of
reinforcing rotator cuff repairs with ePTFE augmented
sutures. 2012 Biennial Shoulder & Elbow Society of
Australia, Brisbane, Queensland.
Shepherd H,Ronquillo J,Lam P,Murrell GAC. (2012) ePTFE
patch repair for irrepairable rotator cuff tears. 2012
Biennial Shoulder & Elbow Society of Australia, Brisbane,
Queensland.
Lam P,Shepherd HM,Murrell GAC. (2012) Biomechanical
analysis of Fiber Tape versus Fiberwire in rotator cuff
repair. The St George and Sutherland Hospital Medical
Research Symposium, October 2012.
Khoo J,Wei AQ,Lam P,Ronquillo J,Murrell GAC. (2012)
Biomechanics and cytotoxicity of suture anchors used in
labral repairs. The St George and Sutherland Hospital
Medical Research Symposium, October 2012.
Kroslak M,Murrell GAC. (2012) Surgical treatment of
lateral epicondylitis: a prospective., randomised, placebo
controlled pilot study. The St George and Sutherland
Hospital Medical Research Symposium, October 2012.
Lam PH,Hansen K,Keighley G,Briggs L,Murrell GAC. (2012)
A randomised double blined clinical control trial evaluating
the effectiveness of daily vibration following arthroscopic
rotator cuff repair. The St George and Sutherland Hospital
Medical Research Symposium, October 2012. Poster.
Le BTN,Wu X,Lam PH,Murrell GAC. (2012) Factors
predicting rotator cuff re-tear: An analysis of 1000
consecutive rotator cuff repairs. The St George and
Sutherland Hospital Medical Research Symposium,
October 2012, Poster.
Tham L,Briggs L,Murrell GAC. (2012) Ultrasound changes
after rotator cuff repair – is supraspinatus tendon thickness
related to pain? The St George and Sutherland Hospital
Medical Research Symposium, October 2012. Poster.
Shepherd HM,Lam PH,Murrell GAC. (2012) Interpositoin
PTFE patch repair vs direct rotator cuff repair in an ovine
model. The St George and Sutherland Hospital Medical
Research Symposium, October 2012. Poster.
99
Briggs L, Peters K, Murrell GAC. (2012) Ultrasound-guided
versus blind subacromial corticosteroid injection for
subacromial impingement. 4th International Compress on
Physical Activity and Public Health, Australian Conference
of Science and Medicine in Sport, National Sports Injury
Prevention Conference, Sydney. Journal of Science and
Medicine in Sport, 15, 6, p 373.
Kurz A,Kelly M,Briggs L. Murrell GAC. (2012) Adrian Kurz:
Effect of surgeon-sonographer interaction on ultrasound
diagnosis of rotator cuff tears: A five-year cohort study
in 775 shoulders. 4th International Compress on Physical
Activity and Public Health, Australian Conference of
Science and Medicine in Sport, National Sports Injury
Prevention Conference, Sydney. Journal of Science and
Medicine in Sport, 15, 6, p 373.
Molnar R, Computer Navigated Total Hip Arthroplasty
- Can It Be Simple And Accurate? The Annual Scientific
Meeting of the Arthroplasty Society, June (2012),
Melbourne.
Harris I A, ACI 2nd Annual Musculoskeletal Network
Forum: Pre, peri and post-operative care in primary total
hip and knee replacement: a review of the evidence.
Sydney, 4 May 2012.
Harris I A, NSW AOA Annual Scientific Meeting 2012:
Sydney 17 August 2012.
•
Complications and diagnostic investigations after hip
and knee arthroplasty in English proficient and nonEnglish proficient patients
•
Is centre-based care superior to a home program after
total knee replacement? A single blind randomized
controlled trial
•
Why don’t people participate in randomized trials in
surgery?
•
Mail versus telephone administration for Oxford hip
and knee scores
•
ANZ Hip Fracture Registry
•
The effect of a single passive intervention to improve
patient satisfaction in an orthopaedic service
•
Are subacute outcomes following TKR and THR
different in patients who have limited English
proficiency?
Kroslak M,Murrell GAC. (2012) Surgical treatment of
lateral epicondylitis: A prospective, randomised, blinded,
placebo controlled pilot study. 4th International Compress
on Physical Activity and Public Health, Australian
Conference of Science and Medicine in Sport, National
Sports Injury Prevention Conference, Sydney. Journal of
Science and Medicine in Sport, 15, 6, p 374.
•
Total hip replacement in haemodialysis and renal
transplant patients – a systematic review
•
Dose dependent effects of intra-articular injection of
tranexamic acid on bleeding in total knee arthroplasty.
Lam PH,Shepherd H,Murrell GAC (2012). Biomechanical
comparison of two arthroscopic rotator cuff repair
techniques using synthetic scaffolds as a bridging device
in an ovine model. 4th International Compress on Physical
Activity and Public Health, Australian Conference of
Science and Medicine in Sport, National Sports Injury
Prevention Conference, Sydney. Journal of Science and
Medicine in Sport, 15, 6, p 157.
•
Rates of lumbar spine surgery, revision and mortality
rates for NSW, 2000-2008
•
Pulsed electromagnetic field stimulation for acute
tibia fractures: a multicentre double blind randomised
controlled trial
•
Trends in arthroscopic surgery and conversion to TKR:
NSW 2000-2008
Leason S,Briggs L, Murrell GAC (2012) The effectiveness
of ultrasound in diagnosis of adhesive capsulitis: A pilot
study. 4th International Compress on Physical Activity
and Public Health, Australian Conference of Science
and Medicine in Sport, National Sports Injury Prevention
Conference, Sydney. Journal of Science and Medicine in
Sport, 15, 6, p 158.
•
Predictors of discordance in patients and surgeon
satisfaction after hip and knee replacement
•
Is a 30 minute walk test useful after a knee
replacement?
•
Why don’t people participate in randomized trials in
surgery?
Le B,Wu X,Murrell GAC (2012). Factors predicting rotator
cuff re-tear rate: An analysis of 1000 consecutive rotator
cuff repairs. 4th International Compress on Physical
Activity and Public Health, Australian Conference of
Science and Medicine in Sport, National Sports Injury
Prevention Conference, Sydney. Journal of Science and
Medicine in Sport, 15, 6, p 373.
Lam PH, Hansen K, Keighley G, Briggs L,Murrell GAC.
(2012) A randomised double blinded clinical control trial
evaluating the effectiveness of daily vibration following
arthroscopic rotator cuff repair. 4th International Compress
on Physical Activity and Public Health, Australian
Conference of Science and Medicine in Sport, National
Sports Injury Prevention Conference, Sydney. Journal of
Science and Medicine in Sport, 15, 6, p 374.
100
Harris I A, AOA Annual Scientific Meeting: Sydney, 8-11
October 2012
•
The evidence base for common orthopaedic
procedures
Harris I, 2nd Annual Whitlam Orthopaedic Research Centre
Symposium August 10, 2012, Liverpool Hospital NSW
•
ANZ Hip Fracture Registry
•
•
Total hip replacement in haemodialysis and renal
transplant patients – a systematic review
Patient satisfaction after total joint replacement:
private versus public
•
Spine surgery outcomes in a workers compensation
environment
Elective total hip and knee replacements: a review of
the evidence
•
Dose dependent effects of intra-articular injection of
tranexamic acid on bleeding in total knee arthroplasty
Patient preference for rehabilitation after joint
replacements
•
Peri-articular steroid injection in total knee
arthroplasty: a prospective double blinded
randomized controlled trial
Mail versus telephone administration for Oxford hip
and knee scores
•
The evidence base for common orthopaedic
procedures Mortality after surgery in NSW.
•
The CROSSBAT trial: lessons for conducting
multicentre randomized trials in orthopaedics in
Australia
Harris I A, Australian Physiotherapy Association Annual
Meeting: Improving access to elective joint replacement
surgery: a waitlist cohort. Melbourne, October 2013.
•
Are orthopaedic randomized trials generalisable? A
comparison with other surgical specialties
Harris I A, Ingham Institute Annual Research and Teaching
Showcase: Sydney, November 2013
•
Scientific and reporting quality of orthopaedic
randomized trials: a comparison with other surgical
specialties
•
Monitoring hip or knee arthritis: measurement error in
patient outcomes
•
Tranexamic Acid to reduce blood transfusion in hip
fracture surgery
•
Inter-rater reliability in clinical registry data collection
•
Accuracy and completeness data audit of the
Arthroplasty Clinical Outcomes Registry
•
Opioid dependence after major orthopaedic trauma
•
Opioid dependence after minor motor vehicle trauma.
•
•
•
•
Emergency pelvic fracture care: acute interventions
are required in haemorrhagic shock (debate)
Harris I A, AOA Continuing Orthopaedic Education:
Melbourne, 1-3 March 2013
•
Orthopaedic Trauma: Distal radius fractures – internal
fixation is rarely necessary
•
The CROSSBAT Trial: lessons learned from a
multicentre RCT.
Harris I A, AOA Continuing Orthopaedic Education “ShortSharp” meeting - How I got into research: Sydney, 26 July
2013
Harris I A, NSW AOA Annual Scientific Meeting: Sydney,
23 August 2013
•
Over half of Australian orthopaedic trainees are
burned out: results from a nationwide cross-sectional
study
•
Australian orthopaedic surgeons are highly satisfied
with their careers: results from a nationwide crosssectional study
•
ACORN: The Arthroplasty Clinical Outcomes Registry,
NSW – what is it and why do we need it?
•
A comparison of alignment using patient specific
instruments, computer navigation and conventional
instrumentation in total knee Arthroplasty.
Harris I A, Osteoarthritis and viscosupplementation
experts’ debate: The clinical evidence against
viscosupplementation: Sydney, 27 June 2013
Harris I A, Raising Expectations in Rheumatology, Surgical
recommendations – be wary: Melbourne, 28 July 2013.
Harris I A, St George Hospital Osteoarthritis Symposium:
ACORN: The Arthroplasty Clinical Outcomes Registry,
NSW – what is it and why do we need it?, The clinical
evidence against injection therapy for osteoarthritis of the
knee, Kogarah.
Harris I A, SWSLHD Allied Health Research Forum,
Improving access to elective joint replacement surgery: a
waitlist cohort. Liverpool NSW.
Harris I A, Western Orthopaedic Group of Surgeons
Annual Meeting, The clinical evidence against injection
therapy for osteoarthritis of the knee. Bowral, 30
November 2013.
101
Harris I A, Workers Compensation Conference, Spine
surgery and injections: the case for restraint. Sydney, 24
August 2013.
2013 - International
Murrell GAC, 12th International Congress of Shoulder
and Elbow Surgery (ICSES 2013), Nagoya, Japan. Lecture:
Biological and synthetic patches for irreparable rotator cuff
tears.
Murrell GAC, 36th Annual Scientific Meeting Singapore
Orthopaedic Association, Singapore, 8-12 October 2013
Lecture: Permanent versus biodegradable anchors for
arthroscopic stabilisation for traumatic anterior shoulder
instability. Lecture: Rotator cuff tears - pathology and
imaging. Lecture: Undersurface rotator cuff repair.
Debate: Single row (*) versus double row for rotator
cuff repair. Symposium: Rotator cuff repair with knotless
system. Lecture: Biological and synthetic patches for
irreparable rotator cuff tears.
Arora M, Diwan AD, Harris IA; “Burnout among
orthopaedic surgeons”. Indian Orthopaedic Association
Conference 2013 - Podium Presentation, India.
Le BTN, Wu X, Lam PH, Murrell GAC. (2013) Factors
predicting rotator cuff re-tear: An analysis of 1000
consecutive rotator cuff repairs. Open Meeting of the
American Shoulder and Elbow Surgeons, held on Specialty
Day, Saturday, March 23, 2013, in Chicago, IL.
Le BTN,Wu X,Lam PH,Murrell GAC. (2013) Factors
predicting rotator cuff re-tear: An analysis of 1000
consecutive rotator cuff repairs. AOSSM 2013 Specialty
Day, March 23, 2013, Chicago, IL. Paper 16.
Peters K; Pirapakaran K Murrell GAC (2013) Permanent
outperforms biodegradable anchors for arthroscopic
shoulder stabilization. AOSSM 2013 Specialty Day, March
23, 2013, Chicago, IL. Paper 12.
Kurz AK, Kelly MJ, Briggs L, Murrell GAC (2013) Surgeonsonographer interaction on ultrasound diagnosis of rotator
cuff tears: Five-Year Study in 775 Shoulders. AAOS Annual
Meeting, March 19-23, Chicago, IL, paper 498.
Le BTN,Wu X,Lam PH,Murrell GAC. (2013) Factors
predicting rotator cuff re-tear: An analysis of 1000
consecutive rotator cuff repairs. AAOS Annual Meeting,
March 19-23, Chicago, IL, paper 122.
Dines J,Bedi A,Rodeo S,Murrell GAC. (2013) Biologic
Augmentation of Tendon-Bone Healing in the 21st
Century: Where are we now? Instructional Course Lecture.
AAOS Annual Meeting, Chicago, IL.
Murrell GAC. (2013) Biological and synthetic patches for
irreparable rotator cuff tears. 12th International Congress
102
of Shoulder and Elbow Surgery (ICSES 2013), Nagoya,
Japan. Invited paper SSY-1-1.
Murrell GAC. Shepherd H,Ronquillo J,Lam P. (2013)
ePTFE patch repair for irreparable rotator cuff tears. 12th
International Congress of Shoulder and Elbow Surgery
(ICSES 2013), Nagoya, Japan. Paper SO-13-3.
Murrell GAC, Peters K,Khoo J,Wei A,Ronquillo J,Lam
P. Permanent outperforms biodegradable anchors for
arthroscopic stabilisation. 12th International Congress of
Shoulder and Elbow Surgery (ICSES 2013), Nagoya, Japan.
Paper SO-14-9.
Arora M, Diwan AD, Harris IA; “Australian orthopaedic
surgeons are highly satisfied with their careers: results from
a nationwide cross-sectional study”. Indian Orthopaedic
Association Conference 2013 - Poster Presentation, India.
Arora M, Diwan AD, et al; “PMMA bone cements
and additives: A review of the literature”; 34th SICOT
Orthopaedic World Congress – Poster Presentation, India,
Abstract number – 33557.
Arora M, Diwan AD, et al; PMMA bone cements and
additives: Review of literature”. 19th Asian Congress of
Surgery and 1st Singhealth Surgical Congress 2013 –
Poster Presentation, Singapore.
Briggs L,Lam P,Millar N,Murrell GAC. Are the symptoms
of calcific tendonitis due to neoinnervation and/or
neovascularisation? 2014 AAOS Annual Meeting, March
11-15, New Orleans, Louisiana, Paper 515.
Shamsudin A,Lam P,Murrell GAC. Primary versus revision
arthroscopic rotator cuff repair - an analysis in 350
consecutive patients. 2014 AAOS Annual Meeting, March
11-15, New Orleans, Louisiana, Poster # P322.
Hawthorne J,Carpenter E,Lam P,Murrell GAC. Effect of
glenohumeral abduction on supraspinatus repair tension.
2014 AAOS Annual Meeting, March 11-15 in New Orleans,
Louisiana, Poster # P315.
Shamsudin A,Lam P,Murrell GAC. Primary versus revision
arthroscopic rotator cuff repair - an analysis in 350
consecutive patients. 2014 AOSSM Specialty Day, March
11-15 in New Orleans, Louisiana, Paper.
Harris I A, AO Masters Course – Current Concepts
Interprosthetic and Vancouver C fractures
History of pilon fractures Complex tibial plateau fractures
and fracture-dislocations. Dubai, 28 September 2013.
2013 - National
Murrell GAC, Australian Sonographers Association Annual
Meeting, Sydney. Plenary Lecture: Clinical assessment of
shoulder and biomechanics, 2013, Sydney.
Arora M, Diwan AD, et al; “PMMA bone cements
and additives: a review of the literature”; Australian
Orthopaedic Association Annual Meeting 2013 - Poster
Presentation, Australia.
Arora M, Diwan AD, Harris IA; “Australian orthopaedic
surgeons are highly satisfied with their careers: results
from a nationwide cross-sectional study”; Australian
Orthopaedic Association Annual Meeting 2013 - Podium
Presentation, Australia.
Arora M, Diwan AD, Harris IA; “Over half of Australian
orthopaedic trainees are burned out: results from a
nationwide cross-sectional study”; Australian Orthopaedic
Association Annual Meeting 2013 - Podium Presentation,
Australia.
Arora M, Diwan AD, Harris IA; “Australian orthopaedic
surgeons are highly satisfied with their careers: results
from a nationwide cross-sectional study”; New Zealand
Orthopaedic Association Annual Meeting 2013 - Poster
Presentation, New Zealand.
Arora M, Diwan AD, Harris IA; “Over half of Australian
orthopaedic trainees are burned out: results from
a nationwide cross-sectional study”; New Zealand
Orthopaedic Association Annual Meeting 2013 - Poster
Presentation, New Zealand.
Arora M, Diwan AD, Harris IA; “Australian orthopaedic
surgeons are highly satisfied with their careers: results
from a nationwide cross-sectional study”; Australian
Orthopaedic Association NSW Branch Annual Meeting
2013 - Podium Presentation, Australia.
Arora M, Diwan AD, Harris IA ; “Over half of Australian
orthopaedic trainees are burned out: results from a
nationwide cross-sectional study”; Australian Orthopaedic
Association NSW Branch Annual Meeting 2013 - Podium
Presentation, Australia.
Community Engagement
Dr Ashish Diwan, Spinal Surgeon, Department of
Orthopaedic Surgery, raised $140,000 donations for the
UNSW foundation for spine research and education.
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Department of Trauma Services
Head of Department
Dr Mary Langcake, FRACS, BMBS, BSc
Senior Medical
Dr Christine Bowles, MBBS, FACEM
Dr Anthony Chambers, BSc, MBBS, MS, FRACS
Dr Anthony Morgan, MD, PhD
Nursing
Kate Curtis, CNC, RN, MNurs (Hons), PhD
Conjoint Associate Professor, February 2010 – June 2017
St George Clinical School, University of NSW
Honorary Professorial Fellow, June 2010 – June 2014
The George Institute for Global Health
Visiting Associate Professor, May 2013 – May 2015
Faculty of Health Sciences and the Organisation and
Delivery of Care Research Group
University of Southampton, England
Taneal Wiseman, CNC
Belinda Kennedy, CNS
Liz Walter, CNS
Sarah Kourouche, CNS
Jane Leroi, RN
Belinda Munroe, CNS
Research Grants
Motor Accidents Authority of NSW, NSW Small Grants
round. Kate Curtis, Lynne Roberts, Mary Langcake.
Improving the care and outcomes of patients with blunt
chest injury. $14,814, 2013-14.
Motor Accidents Authority of NSW, NSW Small Grants
round. Kate Curtis, Helen Goldsmith, Mary Langcake.
Improving outpatient pain management.
$13, 676, 2013-14.
Motor Accidents Authority of NSW, NSW Small Grants
round. Taneal Wiseman, Kate Curtis, Sandra West.
E-learning to improve trauma care on the wards.
$14, 717, 2013-14.
Emergency Care Institute, Kate Curtis, Margaret Murphy,
Jennifer Hardy, Melinda Lewis, Luke Strachan & Tom
Buckley. HiRAID: Evaluation of an emergency nursing
assessment framework on patient assessment and
documentation: A pilot study, $99,457, 2012-14.
104
Day of Difference Foundation, Kate Curtis, Kim Foster,
Rebecca Mitchell, Paediatric Critical Injury Research
Program , $574,223, 2013-2018.
Research Projects in Progress
Does the implementation of a Chest Injury protocol
(ChIP) for patients with blunt thoracic trauma reduce
complications and improve outcomes for patients?
Kate Curtis, Stephen Asha, Annelise Unsworth & Mary
Langcake.
The CONFORM Study - PrediCtors Of analgesia use and
regimeN adherence FollOwing discharge after Major
trauma.
Helen Goldsmith, Kate Curtis & Andrea McCloughen.
Exploring the Role of the Wound Care Clinical Nurse
Consultant in a Tertiary Referral Hospital.
Matthew Dutton, Mary Chiarella & Kate Curtis.
Evaluation of an emergency nursing assessment framework
on patient assessment and documentation: A feasibility
pilot.
Belinda Munroe, Kate Curtis & Thomas Buckley.
Life threatening injury in young people: A mixed methods
study.
Rebekah Ogilvie, Kim Foster, Kate Curtis, Andrea
McCloughen.
Depression, Anxiety and Stress in Major trauma patients
Taneal Wiseman, Kate Curtis &Kim Foster .
What makes an Emergency Nurse? Personality Types/
characteristics .
Belinda Kennedy, Kate Curtis & Donna Waters.
The profile rural trauma presentations.
Maryanne Sewell & Kate Curtis.
The impact of trauma nursing roles on patient outcomes
Liz Walter & Kate Curtis.
Cost of Major Trauma in NSW. University of Sydney:
Nursing, Health Sciences, UNSW TARS, The George
Institute for Global Health, NSW Institute of Trauma and
Injury Management.
Kate Curtis, Deborah Black, Doris Lam, Rebecca Mitchell &
John Myburgh.
The scribe nurse in major trauma: Does level of experience
improve quality of documentation and leadership?
Kate Curtis, Alana Clements, Leanne Horvat & Ramon
Shaban.
Subdural Haemmorrhage in older persons: a comparison
of outcomes between those on anticoagulants at the time
of injury and those not. Stephen Asha, Jaenette Keady,
Kate Curtis & Saeed Kohan.
Integrative Literature review on successful models of care
delivery for severely injured children. Kate Curtis, Kim
Foster, Rebecca Mitchell.
The incidence of paediatric trauma in Australia. Kate
Curtis, Kim Foster, Rebecca Mitchell.
What are the levels of emotional distress, contributing
factors and unmet needs of parents of injured children
throughout the trauma journey? Kate Curtis, Kim Foster,
Rebecca Mitchell.
How is care provided for paediatric trauma patients and
their families? Kate Curtis, Kim Foster, Rebecca Mitchell.
What are the needs of parents of severely injured children
in Australia? Kate Curtis, Kim Foster, Rebecca Mitchell.
Improving outcomes in children suffering major trauma
Kate Curtis, Kim Foster, Rebecca Mitchell.
Original Peer-Reviewed Publications
2012
Asha SE, Curtis KA, Taylor C, Kwok A. Patient-controlled
analgesia compared with interval analgesic dosing
for reducing complications in blunt thoracic trauma: a
retrospective cohort study. Emergency Medicine Journal,
2012. doi:10.1136/emermed-2012-201980
Curtis K, Leonard E: The Trauma Nurse Coordinator in
Australia and New Zealand: Demographics, Role and
Professional Development. Journal of Trauma Nursing
2012, 19(4):214-220.
Ogilvie R, Foster K, McCloughen A & Curtis K. The
experience of surviving life-threatening injury: a qualitative
synthesis. International Nursing Review, 2012, 59(3):312320.
Taylor C, Jan S, Curtis K, Tzannes A, Li Q, Palmer C &
Myburgh J (2012). The cost-effectiveness of physician
staffed Helicopter Emergency Medical Service (HEMS)
transport to a major trauma centre in NSW, Australia.
Injury, 43; 1843–1849
Dutton M & Curtis K (2012). Well-wound therapy: use
of NPWT to prevent laparotomy breakdown. Journal of
Wound Care, 21(8);386-8
Willenberg L, Curtis K, Taylor C, Jan S, Glass P, Myburgh
J (2012). The variation of acute treatment costs of trauma
in high-income countries. BMC Health Services Research,
12(1):267
Curtis K, Mitchell R.J, Chong S.S, Balogh Z.J, Reed D.J,
Clark P.T, D’Amours S, Black D.A, Langcake M.E, Taylor
C.J, McDougall P.A, Cameron P.A (2012). Injury trends
and mortality in severely injured adults in NSW. Medical
Journal of Australia, 197(4): 233-237
Clements A & Curtis K (2012). What is impact of nursing
roles in hospital patient resuscitation? Australasian
Emergency Nursing Journal, 15(2): 108-115.
Mitchell R, Curtis K, Fisher M (2012). Understanding
trauma as a men’s health issue: gender differences in
traumatic injury presentations at a level 1 trauma centre in
Australia. Journal of Trauma Nursing, 19(2), 80-88.
Curtis K, Caldwell E, Delprado A, Munroe B (2012).
Traumatic Injury in Australia and New Zealand. Australasian
Emergency Nursing Journal, 15(1); 45-54.
Frydenberg E, Curtis K, Chong S, Poulos R, Grzebieta R,
Steel T, Nau T (2012). Road Trauma, patterns of injury and
mortality in an Australian trauma centre. Journal of the
Australasian College of Road Safety, 23(1):21-28.
Asha S, Curtis KA, Grant N, Taylor C, Lo S, Smart R, et
al (2012). Comparison of radiation exposure of trauma
patients from diagnostic radiology procedures before and
after the introduction of a panscan protocol. Emergency
Medicine Australasia. 24(1):43-51
Mitchell R, Watson W, Curtis K, Harris I & McDougall
P (2012). Difficulties in establishing long-term trauma
outcomes data collections. Could trauma outcomes
be routinely monitored in New South Wales, Australia:
piloting a 3 month follow-up? Injury, 43(1): 96-102.
105
2013
Malaysia
Wiseman T, Foster K & Curtis K. Mental health following
traumatic physical injury: an Integrative literature review.
Injury. 2013;44(11):1383-1390
Langcake M, Invited Speaker. Training Teams for Trauma,
Surgical Education Program. RACS 81st Annual Scientific
Congress, 10 May 2012, Malaysia.
Taylor C, Curtis K, Jan S & Newcombe M. Helicopter
Emergency Medical Services (HEMS) over-triage and the
financial implications for major trauma centres in NSW,
Australia. BMC Emergency Medicine June 2013, 13:11
Langcake M, Invited Speaker. The Problems with Total
Body Scans, Trauma Surgical Program. RACS 81st Annual
Scientific Congress, 10 May 2012, Malaysia.
Curtis K, Chan D, Lam M, Mitchell R, King K, Leonard
L, D’Amours S, Black D. The profile and cost of major
trauma in older people in New South Wales, Australia.
Australasian Journal on Ageing (online June 2013 DOI:
10.1111/ajag.12059)
Mitchell R, Curtis K, Holland AJ, Balogh ZJ, Evans, J,
Wilson K (2013). Acute costs and predictors of higher
treatment costs for major paediatric trauma in New
South Wales, Australia. Journal of Paediatrics and Child.
49(7):557-63
Munroe B, Curtis K, Considine J, Buckley T. The Impact
Structured Patient Assessment Frameworks Have on
Patient Care: An Integrative Review. Journal of Clinical
Nursing (2013 Early online DOI: 10.1111/jocn.12226)
McIntosh AS, Curtis K, Rankin T, Cox M, Pang TY, McCrory
P & Finch C. Associations between helmet use and brain
injuries amongst injured pedal- and motor-cyclists: A case
series analysis of trauma centre presentations. Journal of
the Australasian College of Road Safety 2013; 24, 11-20.
Dinh M, Curtis K, Ivers R. The effectiveness of helmets
in reducing head injuries and hospital treatment costs in
Sydney, Australia. A multicentre study. Medical Journal of
Australia 2013; 198 (8): 415-417
Mitchell R, Curtis K, Chong S, Holland AJ, Soundappan
SVS, Wilson KL, Cass DT. Comparative analysis of trends
in paediatric trauma outcomes in Australia. Injury, 2013,
44:97-103.
Presentations at Scientific Meetings and
Conferences
2012 International
Dutton M, Chiarella M & Curtis K (2012). The current state
of knowledge into role, context of practice and impact of
the wound care nurse. 4th Congress of the World Union
of Wound Healing Societies Better Care, Better Life,
September 2-6, Yokohama Japan
Frydenberg E, Curtis K, Chong S, Poulos R, Grzebieta R,
Steel T, Nau T (2012). Road Trauma, Patterns of Injury and
Mortality in an Australian Trauma Centre. Neurosurgery
Section of the Royal Australasian College of Surgeons’
Annual Scientific Congress., 7 – 10 May Kuala Lumpur,
106
2012 National
Dutton M, Chiarella M & Curtis K. The current state of
knowledge into role, context of practice and impact of
the wound care nurse. 10th National Australian Wound
Management Association Conference. Sydney Convention
& Exhibition Centre18 -21 March.
Clements A, Curtis K, Holzhauser K, Horvat L. The
impact of a senior nurse as nurse team leader on
communication and perceptions of leadership in major
trauma resuscitations. 10th International Conference for
Emergency Nursing, 10-12th October, Hobart.
Curtis K, Mitchell R.J, Chong S, Balogh Z.J et al. Injury
trends and mortality in adult patients with major trauma in
New South Wales, Australia, AMDIG 2012 Unlocking the
Value of Mortality Data Workshop. 13 November, Sydney.
Curtis K, Mitchell R.J, Chong S, Balogh Z.J et al. Injury
trends and mortality in adult patients with major trauma
in NSW, 10th International Conference for Emergency
Nursing, 10-12th October, Hobart .
Munroe B, Curtis K, Buckley T, Considine J. The impact of
a structured patient assessment on patients and clinicians.
10th International Conference for Emergency Nursing, 1012th October, Hobart.
Curtis K, Lam M, Mitchell R, Black D et al. Acute costs and
predictors of higher treatment costs of trauma in New
South Wales, Australia. Trauma 2012, 26-28th October,
Perth.
Leonard E, Curtis K. A snapshot: Resources currently
available in trauma services throughout Australia and New
Zealand. Trauma 2012, 26-28th October, Perth.
Curtis K, Leonard L. Australian and New Zealand Trauma
Nurse Coordinators. Who, what and where? Trauma 2012,
26-28th October, Perth.
Clements A, Curtis K, Holzhauser K, Horvat L. The impact
of a senior nurse as nurse team leader on communication
and perceptions of leadership in major trauma
resuscitations. Trauma 2012, 26-28th October, Perth.
Curtis K, Mitchell R.J, Chong S, Balogh Z.J et al. Injury
trends and mortality in adult patients with major trauma in
NSW. Trauma 2012, 26-28th October, Perth.
Curtis K, Invited Speaker. Panel member for moderated
discussion entitled ‘2012 Vision, Challenges, and New
Frontiers in Emergency Care’ Panel 10th International
Conference for Emergency Nursing, 10-12th October,
Hobart. Chaired by Jane Hutcheon.
Curtis K, Invited Speaker: Swan XX Trauma Conference,
Sydney, NSW. July 28-29th 2012 .
Langcake M, Panel Session “Dealing with Uncertainty”.
Whole Person Care 2nd National Symposium. Doltone
House, Sydney. 21 March 2012.
Langcake M, Invited speaker Gunshot Wounds Energy
Transfer. SWAN XX Trauma Conference, Sydney, NSW. 28
July 2012.
2013 International
Chan D, Curtis K, et al. The injury profile and acute
treatment costs of major trauma in older people in New
South Wales” E-Poster Presentation. Trauma Surgery
Section of the Royal Australasian College of Surgeons
Annual Scientific Congress, 6 – 10 May 2013, Auckland,
New Zealand.
Crouch R, Palfrey R, McHale H, Curtis K. Trauma Nurse
Coordinators in England, Major Trauma Coordinator
National Conference, Salford, England, 25th November
2013.
2013 National
Langcake M, Invited Speaker: Inspiring Women in
Medicine. Women in Medicine, Parkville 12 August.
Curtis K, Invited Speaker: Critical aspects of trauma
nursing care 8th Annual Critical Care Conference in the
Vineyards, 9 - 10th May.
Curtis K, Invited Speaker: Trauma nursing innovations 8th
Annual Critical Care Conference in the Vineyards, 9 - 10th
May.
Community Engagement
Langcake M, Teaching on EMST/DSTC. Senior Surgery
Program. RACS 81st Annual Scientific Congress, Malaysia.
7 May 2012.
Langcake M, Invited Speaker: Consequences of Trauma in
Older Patients. Seniors’ Day Injury Prevention Seminar, St
George Leagues Club 21 March 2012.
Langcake M, Probus Club of Revesby. 24 September 2012.
Langcake M Consequences of Trauma in Older Patients.
Seniors’ Day Injury Prevention Seminar, St George Leagues
Club. 21 March 2013.
Langcake M Consequences of Trauma in Older Patients.
The Sutherland Hospital’s Clinical Grand Rounds. 29 April
2013.
Langcake M Experiences in Afghanistan. Probus Club of
Ryde. 28 May 2013.
Wiseman T, Pedestrian Trauma. Seniors Day Injury
Prevention Seminar, 20 March 2013, Mortdale, NSW.
Hosted by Trauma Services, St George Hospital.
Ogilvie R, Curtis K, Palmer C, Lam M, McCloughen A,
Foster K. Incidence and outcomes of major traumatic
injury in the Australian Capital Territory. Canberra Health
Annual Research Meeting (CHARM). 20-23rd August.
Kennedy B, Curtis K, Waters D. The Personality
Characteristics of Emergency Nurses. International
Conference for Emergency Nurses, 9-12 October,
Melbourne.
Ogilvie R, Curtis K, Palmer C, Lam M, McCloughen A,
Foster K. Incidence and outcomes of major traumatic injury
in the Australian Capital Territory. International Conference
for Emergency Nurses, 9-12 October, Melbourne.
Mitchell R, Curtis K et al. Acute care costs and predictors
of higher treatment costs for major paediatric trauma
in NSW. 11th Australasian Injury Prevention & Safety
Promotion Conference, 11-13 November Fremantle,
Western Australia.
Curtis K, Invited Speaker: Management of massive
haemorrhage in trauma. International Conference for
Emergency Nurses, 9-12 October 2013, Melbourne.
107
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Department of Vascular Surgery
Head of Department
Dr Eric Farmer MBBS(Hons) FRACS DDY
Visiting Medical Officers
Dr K Hanel MB BS FRACS DDU
Dr L Lemech MB BS FRACS DDU
Dr G McMullin MB BS FRACS DDU
A/Prof J Iliopoulos MB BS (Hons1) FRACS (Cardiothoracic
and vascular) PhD
Vascular Trainee
Michael Tawadrous, Fellow
Victor Bourke, Vascular SET 3 trainee
Adrian Tchen, Vascular SET 1 trainee
Jill O’Donnell, Fellow
Tam Nguyen, Vascular SET 5 trainee
Saissan Rajendran, Vascular SET 1 trainee
Research Projects in Progress
Prospective evaluation of a model to predict outcomes
following Endovascular Aortic Aneurysm Repair. Chief
Investigator Associate Professor Robert Fitridge, The
Queen Elizabeth Hospital, Adelaide, South Australia. St
George Principal Investigator L.D. Lemech.
Managing trauma in the austere environment: a project
for special operations command of the Australian Army.
J. Iliopoulos, Chief Investigator; Prof W R Walsh (S & ORL
NSW).
Adhesions in lumbar spine surgery. J Iliopoulos, Chief
investigator Prof. WR Walsh (S&ORL UNSW), (Ongoing).
Training of defence force staff in simple tissue handling
procedures in a sheep carcus model, J Iliopoulos, Chief
Investigator Prof W R Walsh (S & ORL UNSW).
Renal Dysfunction in patients undergoing Endoluminal
grafting of Abdominal Aortic Aneurysms. Principle
Inestigator – Taranei Amir-Nizami.
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MENTAL HEALTH
Mental Health Academic
>
Unit / School Of
Psychiatry
110
>
Mental Health Academic Unit /
School Of Psychiatry
Head of Department
Dr Kevin Clarke MBBS(Hons),MHA, Grad Dip FBS,
FRANZCP, Conjoint Lecturer UNSW
Senior Medical
Professor Colleen Loo (MB.BS. (Hons), FRANZCP, MD.
School of Psychiatry UNSW; Research Psychiatrist – Black
Dog Institute
Dr Matthew Boulton, BMBS BSc FRANZCP, Conjoint
Associate Lecturer UNSW
Dr Anne Camac, MBBS, FRANZCP, Conjoint Lecturer
UNSW
Dr Mesut Cetiner, MBBS Bsc (Med) (Hons) FRANZCP,
Certificate POA & Conjoint Lecturer UNSW
Dr Denise Cupina MD, FRANZCP, Conjoint Senior Lecturer
UNSW
Dr Spencer Duke, BMedSci BM BS MRCPsych FRANZCP,
Conjoint Senior Lecturer UNSW
Dr Andrew Gerard, MBBS FRANZCP
Dr Yana Kay, MBBS, BA, PHD FRANZCP, Conjoint Lecturer
UNSW
Dr Andrew Pethebridge, MBBS, MM (Ven Sci), MM,
FRANZCP, FAChAM, Conjoint Senior Lecturer UNSW
Dr Margot Phillips, BABSc (Med) MBBS FRANZCP
Dr Anne Wand, Staff Specialist Psychiatrist, Clinical
Lecturer, USYD, Conjoint Senior Lecturer UNSW
Dr Carmelo Aquilina MD FRCPsych FRANZCP, Senior
Clincial Lecturer, USYD
Dr Kylie GullifordBSc(Hons) MBBS(Hons) FRANZCP
Advanced Certificate Child Psychiatry Child & Adolescent
Psychiatrist Conjoint Lecturer UNSW
Dr Sam Harvey, Consultant Psychiatrist & Clinical
Academic, Consultation Liaison Psychiatry Team Lecturer
UNSW
Dr Aparna Menon MBBS FRANZCP
Staff Specialist Senior Conjoint Lecturer UNSW Mental
Health Rehabilitation Unit, The Sutherland Hospital
Vocational registrars, advanced trainees
Dr Rosalyn Lai (MBBS, MD)
Dr Laura Cotiga (MBBS, MD)
Dr Alison Bautovich (MBBS, MD)
Visiting fellows
Dr Patricia Sanchez-Paez (visiting academic)
Dr Pablo Puras (visiting academic)
110
Dr Herng Nieng Chan (visiting psychiatrist)
Dr Montserrat Porter (visiting academic)
Dr Phern Chern Tor (visiting psychiatrist)
Senior Research Staff
Dr Angelo Alonzo (BA, BSc (Hons), Ph.D)
Dr Donel Martin (MClinNeuroPsych; Ph.D; BA (Hons))
Research Staff
Dr Veronica Galvez-Ortiz (MBBS, MD, Ph.D)
Dr Bronwyn Hegarty (Ph.D)
Stevan Nikolin (BSc)
Natalie Katalinic (BA (Hons))
Research Students
Michael Player (BPsych (Hons), Ph.D)
Kerrie-Anne Ho (BPsych (Hons), Ph.D)
Emily O’Keefe (Medical student, independent learning
project)
Research Grants
NHMRC Project Grant ID 1004152 – Role of neurogenesis
in clinical recovery from depression during ECT:
Application of a novel in vivo magnetic resonance
spectroscopy technology. Dr Michael Valenzuela, Professor
Colleen Loo, Dr Jesus Pujol, Professor Petar Djuric, Dr
Dennis Velakoulis, Associate Professor Murat Yucel,
Professor Mike Dragunow. $505,312 (2011-2013)
NARSAD young Investigator Award – Remediation of
cognitive dysfunction in euthymic bipolar disorder patients
using transcranial direct current stimulation (tDCS), Dr
Donel Martin. $60,000 USD (2011-2012)
Dementia Collaborative Research Centre grant.
Transcranial direct current stimulation (tDCS) to enhance
outcomes from computer facilitated cognitive training in
patients with mild cognitive impairment (MCI). Principal
Investigator Mohan A. Associate Investigators Martin D,
Sachdev P, Brodaty H, Loo C, Gates N. $40,000. 2012.
Stanley Medical Research Foundation. A Controlled Trial
of Transcranial Direct Current Stimulation as a Treatment
for Unipolar and Bipolar Depression. 11T-005. Loo C.
$681,595 USD (2012-2015)
UK MRC/NHS Efficacy and Mechanism Evaluation grant.
Ketamine augmentation of electroconvulsive therapy
to improve outcomes in depression. Anderson et al.
£1,002,385 [Note non UK CIs not permitted. Therefore
Prof Colleen Loo is named as an international expert
adviser on the grant] (2012)
NHMRC Program Grant ID: 1037196.“Depressive and
bipolar disorders: Pathophysiology, phenotypes and
treatment innovations.” Principal investigator Mitchell P,
Schofield P, Parker G, Breakspear M. $7100525. (20132017).
NHMRC Project Grant ID 1051423. Electrical Stimulation
with a “Random Noise” Pattern: A New Approach for the
Treatment of Depression. Principal Investigators Loo C,
Mitchell P, Taylor I. $505 380. (2013-2015)
UNSW Major Research Equipment & Infrastructure Grant.
Near Infrared Spectrosopcy. Loo C, Sachdev P, Mitchell P,
Dokos. $ 44,213. 2012.
St George Medical Research Foundation Establishment
Grant. Does transcranial DirectCurrent Stimulation
(tDCS) enhance outcomes from computerised cognitive
remediation inpatients with schizophrenia? – A randomised
controlled trial in a rehabilitatory setting. Menon A, Loo C,
Martin D, Bowman A. $17,000.. 2012.
RANZCP New Investigator Grant. Does transcranial
DirectCurrent Stimulation (tDCS) enhance outcomes
from computerised cognitive remediation inpatients
with schizophrenia? – A randomised controlled trial in a
rehabilitatory setting. Menon A. $5882. 2012.
NSW Institute of Psychiatry Research Fellowship, 0.5 FTE.
A study of ketamine as an antidepressant treatment. Lai R.
$55,000, 2012.
Research Projects in Progress
Principal Investigator: Professor Colleen Loo (all studies
below)
Genetic Factors, Biomarkers and Outcomes of Brain
Stimulation
An investigation of the effects of trancranial electrical
stimulation
Open pilot trial of temporal lobe transcranial direct current
stimulation (tDCS) for depression
Neuroplasticity induced by transcranial direct current
stimulation treatment.
A pilot study of ketamine as an antidepressant
Investigating direct current stimulation as a treatment for
depression: A controlled clinical trial
A controlled trial of transcranial direct current stimulation
as a treatment for unipolar and bipolar depression
Electrical Stimulation with a “Random Noise” Pattern: A
Novel Approach for the Treatment of Depression
A comparison of transcranial electrical stimulation methods
Anaesthesia in ECT Study
A study of transcranial electrical stimulation (TES) as a
maintenance treatment for depression.
Trial of Bilateral Transcranial Direct Current Stimulation
(tDCS) for the treatment of depression
Low frequency rTMS: A randomized trial
Pfizer Neuroscience Research Grant. A comparative
Study of Intravenous, Intramuscular and subcutaneous
Administration of Ketamine in Depression. Lai R. $40,000,
2013.
Assessment of Suitability for Participation in Research Trials
NSW Institute of Psychiatry Research Fellowship, 0.6
FTE. Treating depression in hemodialysis patients: a
randomised sham controlled trial of transcranial Direct
Current Stimulation (tDCS). Bautovich A. $73 494.30 2013.
Enhancing verbal learning and memory using high
definition transcranial direct current stimulation (HD-tDCS)
RANZCP New Investigator Grant.Treating depression in
hemodialysis patients: a randomised sham controlled trial
of transcranial Direct Current Stimulation (tDCS). Bautovich
A. $6000, 2013.
The effect of repeated and intermittent sessions of
transcranial electrical stimulation on cortical excitability
Remediation of cognitive dysfunction in euthymic
bipolar disorder patients using transcranial direct current
stimulation (tDCS): A pilot study
Transcranial direct current stimulation (tDCS) to enhance
outcomes from computer facilitated cognitive training in
patients with mild cognitive impairment (MCI)
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Original Peer-Reviewed Publications
2012
Bai S, Loo C, Dokos S. A computational model of direct
brain excitation induced by electroconvulsive therapy:
comparison among three conventional electrode
placements. Brain Stimulation 2012; 5(3): 408-421.
Galvez V, Alonzo A, Martin D, Loo C. Transcranial direct
current stimulation (tDCS) treatment protocols. Should
stimulus intensity be constant or incremental over multiple
sessions? Int J Neuropsychopharmacology 2012; 16(1):
13-21.
Loo C, Alonzo A, Martin D, Mitchell P, Galvez V, Sachdev
P. Transcranial direct current stimulation for depression:
3-week, randomised, sham-controlled trial. British Journal
of Psychiatry 2012; 200:52-59.
Loo C, Katalinic N, Martin D, Schweitzer I. A review
of ultrabrief pulse width electroconvulsive therapy.
Therapeutic Advances in Chronic Disease 2012; 3(2) 69-83.
Smith D, Schweitzer, I, Ingram, N, Loo, C. Successful
Ultrabrief ECT for a Mixed Episode of Bipolar Disorder.
Australian & New Zealand J Psychiatry, 2012; 46: no. 4 388
doi: 10.1177/0004867411433954 Letter/ case report.
Kalu, U, Sexton C, Loo C, Ebmeier K. Transcranial Direct
Current Stimulation in the Treatment of Major Depression:
A Meta-Analysis. Psychological Medicine 2012; 42(9):
1791-1800. doi:10.1017/S0033291711003059
Chan, H, Alonzo A, Martin D, Player M, Mitchell P, Sachdev
P, Loo C. Treatment of major depressive disorder by
transcranial Random Noise Stimulation: Case report of a
novel treatment. Biological Psychiatry 2012; 72(4): e9-e10
PMID: 22425412.
Bai S, Loo C, Dokos S. Effects of electroconvulsive
therapy stimulus pulsewidth and amplitude computed
with an anatomically-realistic head model. In: Conference
Proceedings IEEE Engineering in Medicine and Biology
Society, 2012; p. 2559-2562.
2013
Loo C, Garfield J, Katalinic N, Schweitzer I, Hadzi-Pavlovic
D. Speed of Response in Ultrabrief and Brief Pulse Width
Right Unilateral ECT. Int J Neuropsychopharmacology
2013; 16: 755-761.
Loo C. ECT in the 21st Century: Ultrabrief pulse
stimulation – a new development in treatment technique.
Australian Prescriber 2013; 36(1) 22-23.
Perich T., Mitchell, P.B., Loo, C., Hadzi-Pavlovic, D.,
Roberts, G., Lau, P., Wright, A., Frankland, A. Clinical and
demographic features associated with the detection of
early warning signs in bipolar disorder, Journal of Affective
Disorders 2013; 145(3): 336-340. doi.org/10.1016/j.
jad.2012.08.014.
Martin D, Alonzo A, Ho, K-A, Player M, Mitchell P,
Sachdev P & Loo C. Continuation transcranial direct
current stimulation for the prevention of relapse in major
depression. Journal of Affective Disorders 2013; 144: 274278.
Chan H, Alonzo A, Martin D, Mitchell P, Sachdev P, Loo
C. Augmenting transcranial direct current stimulation with
D-cycloserine for depression: A pilot study. J ECT 2013;
29(3):196-200.
Cupina D, Patil S, Loo C. Chronic catatonic schizophrenia
treated successfully with right unilateral ultrabrief pulse
electroconvulsive therapy: A case report. J ECT 2013;
29(2); 134-136.
Player, M, Taylor J, Alonzo A, Loo C. Paired associative
stimulation increases motor cortex excitability more
effectively than theta-burst stimulation. Clinical
Neurophysiology 2012; 123(11):2220-6.
Rae C, Lee V, Ordidge R, Alonzo A, Loo C. Anodal
transcranial direct current stimulation increases brain
pH and modulates bioenergetics. International J
Neuropsychopharmacology, 2013; 16(8); 1695-1706.
Loo C & Martin D. Could transcranial direct current
stimulation have unexpected additional benefits in the
treatment of depressed patients? Expert Review of
Neurotherapeutics. 2012: 12 (7): 751-753.
Bai S, Loo C, Dokos S. A review of computational models
of transcranial electrical stimulation. Critical Reviews in
Biomedical Engineering. 2013;41(1):21-35.
Loo C, Katalinic N, Garfield J, Sainsbury K, Hadzi-Pavlovic
D, MacPherson R. Neuropsychological and mood effects
of ketamine in electroconvulsive therapy: A randomised
controlled trial. J Affective Disorders 2012; 142(1-3): 233240. Faculty of 1000 Recommended.
Chan H, Mitchell P, Loo CK & Harvey S. Treatment resistant
depression: Pharmacological approaches. Medical Journal
of Australia 2012; 1(Supp 4); 44-47.
112
Alonzo A, Chan G, Martin D, Mitchell P, Loo C. Transcranial
Direct Current Stimulation (tDCS) for Depression: Analysis
of Response Using a Three-Factor Structure of the
Montgomery-Åsberg Depression Rating Scale. J Affective
Disorders, 2013; 150(1); 91-95.
Katalinic, N, Lai R, Somogyi, A, Mitchell P, Glue P, Loo CK.
Ketamine as a new treatment for depression: A review of
its efficacy and adverse effects. Australian & New Zealand
J Psychiatry, 2013; 47(8); 710-727.
Galvez, V, Loo C, Alonzo A, Cerrillo E, Menchon J, Crespo
J, Urretavizcaya M. Do benzodiazepines moderate the
effectiveness of bitemporal Electroconvulsive Therapy in
Major Depression? J Affective Disorders 2013; 150(2):686690. doi: 10.1016/j.jad.2013.03.028).
Martin D, Liu R, Alonzo A, Green M, Player M, Sachdev
P, Loo C. Can transcranial direct current stimulation
enhance outcomes from cognitive training? A
randomized controlled trial in healthy participants. Int J
Neuropsychopharmacology 2013; 16(9):1927-1936.
Player M, Taylor J, Weickert C, Alonzo A, Sachdev
P, Martin D, Mitchell P, Loo CK. Neuroplasticity in
Depressed Individuals Compared to Healthy Controls.
Neuropsychopharmacology 2013; 38(11):2101-2108
Corry J, Green M, Roberts G, Frankland A, Wright A, Lau
P, Perich T, Loo C, Breakspear M, Mitchell P. Anxiety, stress
and perfectionism in bipolar disorder. J Affective Disorders
2013; 151(3):1016-1024.
Martin D, Katalinic N, Ingram A, Schweitzer I, Smith
D, Hadzi-Pavlovic D, Loo C. A new early cognitive
screening measure to detect cognitive side-effects of
electroconvulsive therapy? J Psychiatric Research 2013;
47(12):1967-1974.
Presentations at Scientific Meetings and
Conferences
All presentations listed are by Professor Colleen Loo
2012 - International
International Society for ECT and Neurostimulation
Annual Meeting.“Transcranial Direct Current Stimulation”.
Symposiumpresenter.Philadephia, US. 6 May, 2012.
Presentation to Neuroscience Research Unit, University of
Manchester, “Transcranial Direct Current Stimulation: A
New Treatment for Depression?” 11 May, 2012.
2012 - National
NSW Official Visitors Program-Training Day.
“Electroconvulsive Therapy”. 9 February, 2012. Sydney
RANZCP Invited symposium speaker: tDCS. Hobart, May
2012.
Specialist Mental Health Services for Older People
Benchmarking Forum, NSW Health. Guest Speaker –
presentation on ECT.NSW Mental Health Drug and
Alcohol Head Office, Sydney. 5 June, 2012.
ECT and Neurostimulation. Barossa Valley, 1 Sept, 2012.
Invited main speaker, Queensland Neuropsychiatry
Interest Group, “Neurostimulation Forum”. 27th Oct 2012.
Brisbane.
ECT workshop, Royal Melbourne Hospital, 14 Nov 2012.
Session Chair, Health Service Alliance First Annual
Scientific Symposium.“Science and Health for Women in
2012”.Royal Hospital for Women, Sydney.15 Nov, 2012.
2013 - International
Invited plenary speaker. “RUL ultrabrief ECT: further
RCT evidence”. International Society for ECT and
Neurostimulation. San Francisco. 19 May 2013.
2013 - National
NSW Official Visitors Program-Training Day. “Treatment
Approaches in Electroconvulsive Therapy”.1 9 February,
2013. Sydney.
Invited speaker, Professorial Grand Rounds, Westmead
Hospital. “Brain Stimulation: A New Tool in Psychiatry”. 4
July 2013.
Invited speaker, Health-E-Care Hospitals Planning
weekend. “New Directions in Research”. 13-14 July 2013.
Byron Bay, NSW.
Invited Speaker, The Melbourne Clinic. “Multicentre RCT
of Ultrabrief pulse ECT”. Melbourne, 24 July 2013.
Plenary Speaker “Transcranial Direct Current Stimulation”.
Australian Brain Stimulation conference, Melbourne,
Australia. 25-26 July, 2013.
St George Hospital Grand Rounds. “ Neuroplasticity in
health and psychiatric illness”. 5 Sept 2013.
Concord Centre for Mental Health. “Application of Brain
Stimulation in Psychiatry”. 19 September 2013.
Invited speaker, RANZCP Neuropsychiatry and Behavioural
Neurology Conference 8 - 9 November 2013. The
Melbourne Brain Centre, University of Melbourne. “ECT: A
Constantly Evolving Science”.
Speaker “Brain Stimulation is Good for You: ECT & tDCS”.
UNSW Brain Sciences Colloquium. Black Dog Institute, 25
November 2013.
Invited main speaker, Ramsay Healthcare Continuing
Education Workshop on “ECT and TMS”, Adelaide Clinic,
SA, August, 2012.
Invited Speaker, VIC Chief Psychiatrist’s Clinical Practice
Forum: ECT. 3 Dec 2014, Melbourne. [Note all Vic
psychiatrists were invited to attend a special ½ day
forum, convened to discuss ECT policy and practice in
the state of Vic. C Loo was the invited speaker and panel
discussant, to provide expert input into this forum.]
Invited main speaker, SA NeurostimulationRetreat.Talks on
Keynote speaker, ASPR, Melbourne 4-6 Dec 2013.
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Community Engagement
Television
The Project – Special Report, “Going Global:
electroconvulsive therapy”, 12/6/12
“Ketamine” – ABC Catalyst, 25/10/12
tDCS in depression – Channel 9 National News 6pm,
9/2/13.
ECT – Insight program. SBS. 24/9/13.
Radio
Interview-ABC Radio Darwin, on ECT, 19/12/12
Interview about ECT. ABC Radio (WA). 6/3/13.
Interview – Radio Australia, on ECT and tDCS, 6/4/13.
Print Media
“Brainwave is a breakthrough”. St George and Sutherland
Shire Leader. 6/3/12
Ketamine Benefits Depression Patients, says Study
TopNews 7/6/12
Ketamine ‘could relieve depression’, Ninemsn 7/6/12 and
Bulletin Wire, 7/6/12
Ketamine may relieve depression, trials show, Australian
Doctor, 7/6/12
Party drug ‘special k’ may help relieve depression, The
Australian
Also published on Silobreaker, Topix NewKerala News
Track India (Web India 123 Yahoo! Lifestyle India, Big News
Network, The Times of India India4u, Jagran Post, The
Free Library, Hamara News, AndhraNews.net 7/6/12
Depression trial using Ketamine looking for volunteers,
MedIndia.
Common anesthetic discovered to be providing instant
relief to depression sufferers.,TopNews Arab Emirates,
7/06/12
“’Special’ drug set to ease the blues”, Adelaide Advertiser,
8/6/12.
“Shock Value” – Sydney Morning Herald, article about
ECT. 10/11/12
“Special K eases blues”, MX Brisbane, 7/6/12.
Promising Depression Treatment – article about tDCS in
depression New York Times 11/2/13.
“A quiet revolution”, UNSW Uniken (http://uniken.unsw.
edu.au/features/quiet-revolution), 7/6/12.
tDCS in depression. The Globe and Mail, Vancouver.
Interviewed 14/2/13.
“Ketamine could play anti-depressant role”, India Pharma
News (http://www.contify.com/story/ketamine-could-playanti-depressant-role-9041055), 9/6/12
“Lite and easy, Nurse Ratched. Electroconvulsive shock
therapy not like it used to be” & “Going with the Current”
Australian Financial Review. 6/3/13.
Brain cells slower to adapt with depression” Sydney
Morning Herald. 1/6/13
“Warning over gamer’s headset”. DIY tDCS. Sun Herald.
30/6/13.
Web Media
New depression treatment ‘safe and effective’, News
Medical
Electrical stimulation of the brain is a safe treatment for
depression The Conversation
Safe And Effective New Treatment For Depression
MediLexiton 9/3/12
’ Special K’ could relieve depression Daily Telegraph
UNSW Newsroom Virtual Medical Centre Also published
on Sky News, Courier Mail, Medical Xpress Herald Sun,
All Voices, News.com.au, Interceder, Bigpond News, Perth
Now, Adelaide Now, Arizona Health between 6/6/12 7/6/12
114
Party drug treats depression, Sydney Morning Herald, Also
published in Warren Advocate Casey Weekly), Hobsons
Bay Weekly 19/6/12.
Australian researchers test speedy depression drug,
Psychiatry Update 22/6/12
Special K for Depression Renews Hope in Hallucinogens,
Bloomberg Also published in The Frostproof News The
Lake Wales News, The Polk County Democrat, The Fort
Meade Leader 08/7/12-10/7/12
Special K: ketamine’s road from tranquiliser to possible
antidepressant, The Conversation 13/12/12
Depressed brains are less plastic. ABC Science. 28/5/13
WOMEN’S AND
CHILDREN’S
HEALTH
Urogynaecology
>
116
Women’s Health
>
119
>
Department of Urogynaecology
Head of Department
Professor KH Moore MBBS MD FRCOG FRANZCOG CU
Senior Medical
Dr E Karantanis MBBS FRANZCOG MD CU
Junior Medical
Dr N Te West
Dr Z Chen
Research Staff
Dr Ying Chen – Laboratory Scientist
Wendy Allen – Nurse Continence Advisor
Katrina Parkin – Nurse Continence Advisor
Wendy Hayes – Physiotherapist
Research Grants
NHMRC – 2009-2012
Principal investigators – R. Chess-Williams, E. Burcher,
KH. Moore, Non-neuronal ATP: Regulation of release and
Action in the bladder
Total awarded; years funded - $ 420,000; 2009-2012.
UNSW Faculty of Medicine 2012 – “Silver Star” Grant
in recognition of high score non-funded NHMRC Grant
application.
Principal investigators – Professor Kate Moore
Total awarded $20,000.
Thera Vida Randomised Control Trial 2011-2012.
Principal investigators – Professor Kate Moore
Total awarded $30,000.
Research Projects in Progress
Prospective Multicentre observational trial of vaginal
oestriol cream for women with stress incontinence,
KH Moore Sydney, JP Roovers Amsterdam, S Jeffries,
Capetown
Prospective observational study of Patient Motivation
Questionnaire in relation to pelvic floor physiotherapy
compliance, KH Moore, E Karantanis W Hayes, K Parkin, W
Allen.
Randomised placebo controlled trial of antibiotics for
patients with refractory detrusor overactivity, KH Moore, K
116
Mansfield (University of Wollongong), Y Cheng, V Gebski
(University of Sydney)
Development of novel techniques for identification of
intracellular bacteria in human urothelial cells Y Cheng,
K Mansfield (University of Wollongong, KH Moore M
Schembri (University of Queensland).
Original Peer-Reviewed Publications
2012
Shahab RB, Sarma S, Moore KH, Kuteesa WMA, Cebola
M, Walsh CA, Wang YA, Karantanis E. Randomized
Controlled Trial of Cough Test versus no Cough Test in the
Tension-Free Vaginal Tape Procedure effect upon Voiding
Dysfunction and 12 month Efficacy. Int Urogyn J, 2012;
23:435-441.
Karantanis E, Painter V, Moore KH. Does patient activity
level affect 24-hour pad test results in stress-incontinent
women? Neurol & Urodyn 2012; 31: 143-147 .
Ho M, Kuteesa W, Short A, Eastwood A, Moore KH.
Incontinence after childbirth: Long-term analysis of direct
costs of conservative and surgical therapy. Aust NZ Cont J
2012; 18: 10-19
Hannan TJ, Totsiks M, Mansfield KJ, Moore KH, Schembri
MA, Hultgren SJ. Host-Pathogen Checkpoints and
Population Bottlenecks in Persistent and Intracellular
Uropathogenic E Coli Urinary Tract Infection. FEMS
Microbiol Rev. 2012 36:616-48.
2013
Walsh CA, Cheng Y, Mansfield KJ, Parkin K, Mukerjee C,
Moore KH. Decreased intravesical ATP in patients with
refractory detrusor overactivity and bacteriuria. J Urol
2013; 189: 1383-7.
Cheng Y, Mansfield KJ, Allen W, Millard RJ, Burcher E,
Moore KH. Correlation between Cystometric volumes, ATP
release, and pH in women with overactive bladder versus
controls. Neurourol Urodyn. 2013;32:969-73
Mansfield KJ, Cowan T, Cheng Y, Allen W, Moore KH.
Predicting refractory Detrusor overactivity: Are there any
clues at Diagnosis? EMJ Urology 2013; 1: 87-91.
Moore KH, Allen W, Woodman J, Bushati A, Burcher
E. Response to resiniferatoxin in women with refractory
detrusor overactivity: Role of bacterial cystitis. Aust NZ
Cont J 2013; 19: 66-73.
Wong V, Kim S, Moore KH. Why are some women with
pelvic floor dysfunction unable to contract their pelvic floor
muscles? ANZJOG 2013; Oct 1. doi: 10.1111/ajo.12133.
Hagen S, Stark D, Glazener C, Dickson S, Barry S, Elders
A, Frawley H, Galea MP, Logan J, McDonald A, McPherson
G, Moore KH, Norrie J, Walker A, Wilson D, Individualised
Pelvic Floor muscle training in women with pelvic organ
prolapse: a multicentre randomised controlled trial. doi:
10.1016/SO140-6736 (13) 61977-7 Epub 27th Nov 2013
Lancet.
Davidson JE, Moore KH. Is Pelvic Floor Muscle Training
as Effective for Urinary Incontinence in the Elderly as
Compared to the General Population? A&NZ Cont J
2013: 19:18-25.
Deepak I, Sundac L, Benjamin W, Moore KH, Ulett G.
Asymptomatic bacteriuria: prevalence rates of casual
microbes, etiology of infection in different patient
populations, and recent advances in molecular detection.
FEMS Microbiol Lett. 2013; 346: 1-10.
Other Published Material
Book Chapter
Moore KH, Subak L, Wagner TH, De Wachter S, Dudding
T. Economics of Urinary & Faecal Incontinence, and
Prolapse. Report of World Health Organisation, Editors:
Abrahams P, Cardozo L, Koury S, Wein A. 2012; 1829-1861
Health Publications Ltd., Plymouth.
Text Book
Moore, KH. Urogynecology in Evidence Based Clinical
Practice. Second Edition. Textbook. Editor Moore, KH.
2012. ISBN: 9781447142904. Invited to write the second
edition of this monograph by Springer-Verlag, London.
Presentations at Scientific Meetings and
Conferences
2012 International
Mansfield KJ, Cheng Y, Moore KH. Treatment of urothelial
cells with lipopolysacchardie from enteropathogenic
E. Coli reduces stretch induced ATP release. Journal
of Urology 2012; 187: e368-369, American Urological
Assosciation, Chicago.
Cheng Y, Mansfield KJ, Burcher E, Moore KH. ATP
release during bladder filling in women with bladder
oversensitivity. American Urological Assosciation, Chicago
Journal of Urology 2012; 187: e934-e935.
Mansfield KJ, Moore KH, Cheng Y, Schembri M. Effect of
Escherichia coli lipopolysaccharide on stretch-induced ATP
release from cultured urothelial cells. Beijing ICS meeting
Neurourol & Urodyn 2012; 31: 1024-1025.
Bahadory F, Markus I, Cheng Y, Moore KH, Liu L, Burcher
E. Gene expression of purinergic, muscarinic and
tachykinin receptors in porcine bladder: comparison in
fresh tissue and cultured urothelium, myofibroblast and
detrusor muscle cells. 2012 Beijing; Proc. ICS meeting,
Poster.
Cheng Y, Mansfield KJ, Schembri M, Moore KH. Novel
Fluorescent staining methods for detection of adherent
with Intracellular Bacteria in urothelial cells from patients
with refractory urgency. International Urogynaecology
Association ASM (IUGA) Brisbane – Oral Presentation. Int.
Urogyn J, 23; S117-S118.
Hayes W, O’Toole J, Thakkar A, Karantanis E, Moore KH.
Randomized Controlled Trial: Extracorporeal Magnetic
Innervation versus Pelvic Floor Muscle Training in Women
with Stress Urinary Incontinence. 2012 IUGA Brisbane –
Oral Presentation. Int. Urogyn, J, 23; S213-S214.
2012 National
Bahadory F, Markus I, Cheng Y, Moore KH, Liu L, Burcher
E. Gene expression of neurochemical receptors in porcine
bladder and cultured cells: comparison in urothelium,
myofibroblasts and detrusor. St George Medical Research
Foundation. Oct 2012, Prize for Best Poster.
2013 International
Cheng Y, Mansfield KJ, Mukerjee C, Allen W, Schembri
MA, Moore KH. Development of Novel Techniques
for Investigation of Intracellular Bacteria in Urothelial
Cells from Patients with Incontinence. International
Urogynaecological Association Meeting Dublin. Int.
Urogyn J, 2013; 24: 123 – 124.
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Chen Z, Wong V, Moore KH. Nine year subjective and
Objective follow up of the Ultra-lateral Anterior Vaginal
Repair for Cystocoele. International Urogynaecological
Association Meeting, Dublin. Int. Urogyn J, 2013; 24:
59– 61.
Wong V, Guzman RA, Rojas K, Shek K, Chou D,
Moore KH, Dietz P. Predictors of prolapse recurrence
following laparoscopic sacrocolpopexy. International
Urogynaecological Association Meeting Dublin. Int.
Urogyn J, 2013; 24: 64 – 65.
Cheng Y, Moore KH. Comparison of Nitric Oxide release
during urodynamic test between detrusor overactive
women and controls. Neurourol & Urodyn 2013; 32: 74648 International Continence Society Barcelona.
Bahadory F, Burcher E, Moore KH, Liu L. The gene
expression of target proteins and receptors for Botox
in porcine bladder, and down regulation of SNAP-25 in
cultured cells, International Continence Society. August,
Barcelona, poster.
Wong V, Rodirgo Guznian R, Sheu KL, Chow D, Moore
KH, Dietz P. Cystocele recurrence following laparoscopic
sacrocolpopexy: How low does the mesh go? Neurourol
& Urodyn 2013; 32: 705-707 International Continence
Society Barcelona.
Wong V, Kim S, Moore KH. How common is levator
muscle defect in women with acontractile pelvic floor.
International Continence Society, August, Barcelona.
Parkin K, Walsh D, Hayes W, Wong V Karantanis E,
Moore KH. Does the Incontinence treatment motivation
questionnaire (ITMQ) predict response to pelvic
floor physiotherapy for Stress Urinary Incontinence?
International Continence Society August, Barcelona,
poster.
Leek H, Reus A, Stephenson Z, Karantanis E, Moore K.
Clean Intermittent Self-Catheterisation: A randomised
Control Crossover Trial of single-use versus multiple re-use
of non-coated catheters; is cystitis rate altered? Neurourol
& Urodyn 2013; 32: 759-760 International Continence
Society Barcelona.
Cowan T, Mansfield KJ, Cheng Y, Allen W, Moore K. Does
Intravesical ATP or Recurrent Bacterial Cystitis predict
response to antimuscarinics in Detrusor Overactivity.
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International Continence Society August, Barcelona,
poster.
Cheng Y, Mansfield KJ, Allen W, Millard R, Burcher E,
Moore K. Correlation Between Cystometic Volumes,
ATP Release and pH in Women with Overactive Bladder
Versus Controls Neurourol & Urodyn 2013; 32: 969-973
International Continence Society Barcelona.
2013 National
Chen Z, Wong V, Wang A, Moore KH. Nine year
subjective and objective follow up of the Ultra-Lateral
Anterior Vaginal Repair for Cystocoele. UGSA meeting
Garvan Institute of Medical Research, March.
Leek H, Reus A, Stephenson Z, Karantanis E, Moore KH.
Clean Intermittent Self-Catheterisation: An RCT of singleuse versus multiple re-use of Catheters – UTI Risk and Cost
Implications. UGSA meeting Garvan Institute of Medical
Research, March.
Community Engagement
Professor Kate Moore
Professor Kate Moore is the inaugural Chairman of the
Urogynaecological Society of Australasia, a society of
continence clinicians, which aims to promote research,
training and education about pelvic floor dysfunction
across Australia and New Zealand. The Society holds an
Annual Scientific meeting, attended by approximately 200
gynaecologists, physio therapists and nurse continence
advisors, as well as a workshop attached to the RANZCOG
annual meeting and also holds regional meeting (e.g.
Mackay, Cairns). The society administers the Australian
Pelvic Floor Surgery Database, which enables monitoring
of surgical outcomes, including the use of polypropylene
mesh for prolapse surgery.
>
Department of Women’s Health
Head of Department
Professor Michael Chapman – MBBS, MD, FRCOG,
FRANZCOG, CREI
Professor of Obstetrics & Gynaecology Co-Director of
Women’s & Children’s Health St George Hospital, Head of
School - Women’s & Children’s Health UNSW
Senior Medical
Professor Kate Moore – Professor of Obstetrics &
Gynaecology UNSW, Urogynaecologist. MB BS Syd, MD
Liv, FRCOG, FRANZCOG, CU
A/Prof Greg Davis - Senior Staff Specialist Obstetrician
& Gynaecologist, Conjoint A/Prof UNSW/Adj Prof UTS.
MBChB, MD, FRCOG, FRANZCOG
A/Prof Gavin Sacks – Staff Specialist Obstetrician, Fertility
Specialist, Conjoint A/Prof UNSW. MA (Cantab) BM BCh
(Ox) PhD (Ox) MRCOG FRANZCOG CCSST (UK)
Dr John Breen – Staff Specialist Obstetrician &
Gynaecologist, Conjoint Lecturer UNSW. BSc Hons,
MBChB, MRCOG, FRANZCOG
Dr Greg Cario – VMO Obstetrics & Gynaecology,
Laparoscopic Surgeon, Conjoint Senior Lecturer UNSW.
MB, BS (Syd) Hons, FRANZCOG, FRCOG
Dr Danny Chou – VMO Gynaecology, Laparoscopic
Surgeon, Conjoint Lecturer UNSW. MBBS MRCOG
FRANZCOG
Dr Ludmilla Collins – VMO Obstetrics & Gynaecology.
MBBS, FRANZCOG
Dr Amanda Henry – Consultant Obstetrician, Lecturer
UNSW. MA Public Health, FRANZCOG, B.Med. (Hons)
,B.Med.Sci (Hons), DDU(O&G)
Dr Emmanuel Karantanis - Staff Specialist Obstetrician &
Gynaecologist, Conjoint Senior Lecturer UNSW. BSc(Med),
MBBS(Hons), FRANZCOG, PhD, CU
Dr Gavin Kemball – VMO Obstetrics & Gynaecology,
Fertility Specialist, Conjoint Lecturer UNSW. MBBS,
MRCOG, FRANZCOG, BSc, MSc
Dr Chandra Krishnan – Staff Specialist Obstetrician,
Fertility Specialist, Conjoint Lecturer UNSW. MB BS (Syd)
FRANZCOG
Dr Trent Miller – Staff Specialist Obstetrician &
Gynaecologist, Training Supervisor St George Hospital,
Conjoint Lecturer UNSW. MBBS(Hons), FRANZCOG
Dr Michael O’Connor AM – VMO Obstetrics &
Gynaecology, Conjoint Senior Lecturer UNSW. MD. BS
(Hons), MHL (Syd), DCH.DDU.MRCOG (Gold Medal).
FRCOG. FRANZCOG.FACLM.
Dr James Opperman – VMO Obstetrics & Gynaecology.
MBBS (Syd. Hons.), FRANZCOG
Dr David Rosen – VMO Gynaecology, Laparoscopic
Surgeon. MBBS FRANZCOG
Dr Steven Thou – Staff Specialist Obstetrician &
Gynaecologist, Conjoint Lecturer UNSW.BSc (Med) (Hons),
MBBS (Hons), FRANZCOG
Dr Queeny Wong – VMO Obstetrics. MBBS, FRANZCOG
Dr Andrew Zuschmann - Staff Specialist Obstetrician
& Gynaecologist, Fertility Specialist, Conjoint Lecturer
UNSW. BSc(Med) MBBS MReprodMed (UNSW)
FRANZCOG
Junior Medical
Dr Trupti Kanade – Fellow in Laparoscopic Surgery
Dr Shadi Khashaba – Fellow in Reproductive
Endocrinology & Infertility
Dr Joanne McKenna –Fellow in Laparoscopic Surgery
Dr Brian Tsai – Fellow in Laparoscopic Surgery
Dr Christos Venetis – Fellow in Reproductive
Endocrinology & Infertility
Senior Midwifery Research Fellow
Professor Caroline Homer PhD, RN, RM (Professor of
Midwifery, UTS)
Research Midwife
Mrs Lynne Roberts MMid MHSc
Research Grants
NHMRC Project Grant: De Lacey S; Chapman MG; Ratcliffe
J. Acupuncture to improve live birth rates for women
undergoing IVF: a randomised controlled trial. Total Grant:
$634,969 (2011-15).
ARC Discovery Grant: Foureur M, Homer CSE, Fenwick J,
119
Davis D, Sorensen R, Forbes I. Theorising the relationship
between birth unit design and the communication patterns
of labouring women and their maternity care providers.
2012: $91,340; 2013: $86,140.
NHMRC Project Grant: Homer CSE, Ellwood D, Oats J,
Foureur MJ, Sibbritt D, McLachlan H, Forster D, Dahlen
H. Birthplace in Australia: A prospective cohort study.
$790,175 (2012-2015).
NHMRC Project Grant: Homer CSE, Foureur MJ, Davis
D, Adams J, Porteous A. Does Continuity Of Midwifery
Care Increase Vaginal Birth After Caesarean (VBAC): A
Randomised Controlled Trial. $257,550 (2012-2015).
NHMRC Project Grant:– Kildea S, Martensson L, Webster
J, Homer CSE, Stapleton H, Beckmann M, Gao Y, Gibbons
K. Impact on Caesarean Rates following Injections of
Sterile Water (ICARIS) – A randomised controlled trial.
$456,760 (2012-2014).
St George and Sutherland Medical Research Foundation.
Clinical Researcher Award for 2013. Henry A, $20,000,
(2013).
Australasian Society of Ultrasound in Medicine Research
Grant Fetal cardiovascular evaluation after maternal
betamethasone Vs dexamethasone administration. Welsh
A, Henry A, Shand A. $15,000 (2012).
UNSW Medicine Major Research Equipment and
Infrastructure Initiative. Henry A, Welsh A, Abbott J,
Nesbitt-Hawes E, Schindler, T. $100,000, (2013).
Research Projects in Progress
Fetal cardiovascular response to maternal corticosteroid
administration: a comparison of dexamethasone versus
betamethasone” (Short title: SUPER-A*STEROID). Henry A,
Welsh AW, Shand A, Crowther C, Davis G, Palmer A.
Fetal Doppler and the Tei index for evaluation of normal
and pathological pregnancy. Henry A, Welsh AW.
Third trimester ultrasound: an audit of current practices at
St George Hospital. Henry A, King K, Foo J.
Midwifery-led intervention group for pregnant women of
high body mass index: engagement with and outcomes of
SSWInG. Henry A, Chwah S, Reilly A, Hall B, O’Sullivan A.
Triggers for delivery in pre-eclampsia: a retrospective
cohort study. Henry A, Varnier N, Brown M, Pettit F,
Mangos G, Davis G.
Trajectory of platelets in pregnancy. Henry A, Duong C,
Kidson-Gerber G.
Postpartum Physiology, Psychology and Paediatric (P4)
follow up study. Principal Investigator Davis G.
120
Department of Women’s Health is a Collaborating Centre
for the following multicentre randomised controlled trials:
Australasian antenatal Study To Evaluate the Role Of
Intramuscular Dexamethasone versus betamethasone
(ASTEROID) Study. Principal Investigator: Prof Caroline
Crowther. University of Adelaide and Women’s and
Children’s Hospital, Adelaide. Site Investigator SGH A/Prof
Greg Davis.
Candida in Pregnancy study (CiPS). Principal Investigator:
Prof Jonathon Morris. University of Sydney at Royal North
Shore Hospital. Site Investigator SGH: A/Prof Greg Davis.
MAgnesium sulphate at 30 to 34 weeks’ GEstational
age: Neuroprotection TriAl (MAGENTA). Principal
Investigator: Prof Caroline Crowther. University of Adelaide
and Women’s and Children’s Hospital, Adelaide. Site
Investigator SGH: A/Prof Greg Davis.
Preterm Prelabour Rupture Of Membranes close to Term
(PPROMT) Trial. Principal Investigator: Prof Jonathan
Morris. Royal North Shore Hospital, Sydney. Site
Investigator SGH: A/Prof Greg Davis.
PROGesterone after previous preterm birth for the
prevention of neonatal RESpiratory distress Syndrome
(PROGRESS) Trial. Principal Investigator: Prof Caroline
Crowther. University of Adelaide and Women’s and
Children’s Hospital, Adelaide. Site Investigator SGH: A/
Prof Greg Davis.
Triggers for pre eclampsia. Principal Investigator: Dr Jane
Ford. University of Sydney at Royal North Shore Hospital.
Site Investigator SGH: A/Prof Greg Davis.
Original Peer-Reviewed Publications
2012
Amari E, Fowler C, Homer CSE. Bed sharing with infants
in a time of SIDS awareness. Neonatal Paed Child Health
Nurs 2012;15(2): 3-7.
Brown MA, Roberts LM, Mackenzie C, Mangos GJ, Davis
GK. A Prospective Randomised study of Automated
versus Mercury blood pressure recordings in hypertensive
pregnancy (PRAM study). Hypertens Preg. 2012; 31:107119.
Budden A, Henry A, Heatley E. Oxytocin infusion
regimens for induction of labour (protocol). Cochrane
Library, Issue 3, 2012.
Catling-Paull C, Foureur MJ, Homer CSE on behalf of the
members of the Publicly-funded Homebirth Consortium.
Publicly-funded homebirth models in Australia. Women
Birth 2012; 25: 152-158.
Dahlen HG, Homer CSE. Web-based News Reports on
Midwives Compared with Obstetricians: A Prospective
Analysis. Birth. Article first published online: 9 Jan 2012.
DOI: 10.1111/j.1523-536X.2011.00512.x
Dahlen, H.G., Homer, CSE. Motherbirth or childbirth? A
prospective analysis of vaginal birth after caesarean blogs.
Midwifery 2012;29: 167-173.
Henry A, Clements S, Kingston A, Abbott J. In search
of work/life balance: trainee perspectives on part-time
obstetrics and gynaecology specialist training. BMC Res
Notes 2012; 5:19 doi:10.1186/1756-0500-5-19
Hawkins T, Roberts J, Mangos G, Davis G, Roberts L,
Brown M. Plasma uric acid remains a marker of poor
outcome in hypertensive pregnancy: A retrospective
cohort study. BJOG.2012; 119:484-492.
Hawkins TL, Brown MA, Mangos GJ, Davis GK. Transient
gestational hypertension: Not always a benign event. Preg
Hypertens: Int J Women’s Cardiovasc Health 2012; 2(1):
22-27.
Homer CSE, Catling-Paull C. Safe timing for an urgent
caesarean section: What is the evidence to guide policy?
Aust Health Rev 2012; 36 (3): 277-281.
Homer CSE, Allende T, Pekin F, Caplice S, Catling-Paull C,
Foureur MJ. It’s more than just having a baby. Women’s
experiences of a maternity service for Aboriginal and
Torres Strait Islander families. Midwifery 2012;28(4):
E449-E455.
Homer CSE, Griffith M, Brodie PM, Kildea S, Curtin A,
Ellwood D. Developing a core competency model and
educational framework for primary maternity services: a
national consensus approach. Women Birth 2012; 25(3):
122-127.
Homer CSE, Lees T, Stowers P, Aiavao F, Sheehy A, Barclay
LM. Traditional birth attendants in Samoa: Integration with
the formal health system. Int J Childbirth. 2012; 2(1): 5-11.
Ith P, Dawson A, Homer CSE. (2012) Quality of Maternity
Care Practices of Skilled Birth Attendants in Cambodia. Int
J Evid Based Healthc 10: 60–67.
Koch J; Rowan K; Rombauts L; Yazdani A; Chapman M;
Johnson N. Endometriosis and Infertility - A consensus
statement from ACCEPT (Australasian CREI Consensus
Expert Panel on Trial evidence) Aust N Z J Obstet
Gynaecol 2012; 52: 513 – 522.
Moore KH, Shahab RB, Walsh CA, Kuteesa WM, Sarma S,
Cebola M, Allen W, Wang YA, Karantanis E. Randomized
controlled trial of cough test versus no cough test in the
tension-free vaginal tape procedure: effect upon voiding
dysfunction and 12-month efficacy. Int Urogynecol J.
2012; 23(4):435-41.
Painter V, Karantanis E, Moore KH. Does patient activity
level affect 24-hr pad test results in stress-incontinent
women? Neurourol Urodyn. 2012;31(1):143-7
Smith RM, Brodie PM, Homer CSE. (2012) Reviewing
and reflecting on practice: the midwives experiences of
credentialing. Women Birth 2012; 25: 159-165.
Roth H, Homer CSE, Fenwick J.) “Bouncing back”:
How Australia’s leading women’s magazines portray the
postpartum ‘body’. Women Birth 2012; 25:128-128.
Sacks G; Fay L; Chapman M; Smith S; Yang Y; Gowen E.
Detailed Analysis of Peripheral Blood Natural Killer Cells in
Women with Repeated IVF Failure. Am J Reprod Immunol.
2012; 67: 434 – 442.
Shahheidari M, Homer CSE. Impact of the design of
Neonatal Intensive Care Units on neonates, staff, and
families: A systematic literature review. J Perinat Neonat
Nurs 2012; 26(3):260-6.
Smith CA; de Lacey S; Chapman M; Ratcliffe J; Norman
RJ; Johnson N; Sacks G; Lyttleton J; Boothroyd C.
Acupuncture to improve live birth rates for women
undergoing in vitro fertilization: A protocol for a
randomized controlled trial. Trials 2012, 13:60
Smith, R, Gray, J, Raymond, J, Catling-Paull, C, Homer,
CSE. Integrating simulation into a theoretical subject
for midwifery students. Clin Simul Nurs. 2012; 8(9):
e451-e457.
Vaughan G, Pollock W, Peek M, Knight M, Ellwood
D, Homer CSE, Jackson-Pulver L, McLintock C, Ho T,
Sullivan EA. Ethical issues: the multi-centre low-risk ethics/
governance review process and AMOSS. Aust N Z J
Obstet Gynaecol 2012; 52:195–203.
Wheeler J, Davis D, Brodie PM, Fry M, Homer CSE. Is
Asian ethnicity an independent risk factor for severe
perineal trauma in childbirth? A systematic review of the
literature. Women Birth 2012; 25(3):107-13.
2013
Catling-Paull C, Coddington R, Foureur M, Homer CSE.
Publicly-funded homebirth in Australia: A review of
maternal and neonatal outcomes for the last 6 years. Med
J Aust 2013;198(11): 616-620.
Chambers GM; Wang YA; Hoang VP; Sullivan EA;
Chapman MG; Ledger W; Abdalla HI. What can we
learn from a decade of promoting safe embryo transfer
practices? A comparative analysis of policies and
outcomes in the UK and Australia, 2001-2010. Hum
Reprod 2013; 28: 1679 - 1686
Chapman MG; Sacks G. Recurrent miscarriage:
Investigating the potential causes. Med Today. 2013. 13:
61 - 65
121
Dawson A, Brodie PM, Copeland F, Rumsey M, Homer
CSE. Collaborative approaches towards building
midwifery capacity in low income countries: A review of
experiences. Midwifery; Epub 2013 Jul 1, doi: 10.1016/j.
midw.2013.05.009.
Homer CSE, Catling CJ, Scarf VL, Sibbritt D. The profile of
women who consult midwives in Australia. Women Birth
2013;26: 240-245.
Ith P, Dawson A, Homer CSE. Women’s perspective of
maternity care in Cambodia. Women Birth 2013;26: 71–75.
Dawson, AJ, Buchan J, Duffield, C, Homer CSE,
Wijewardena, K. Task shifting and sharing in maternal and
reproductive health in low-income countries: A narrative
synthesis of current evidence. Health Policy Plan 2013; doi:
10.1093/heapol/czt026.
Ith P, Dawson A, Whelan A, Homer CSE. Practices of
skilled birth attendants during labour, birth and the
immediate postpartum period in Cambodia. Midwifery
2013;29(4): 300-7.
Dawson A; Homer C. Managing the International
Humanitarian and Development Health Workforce: A
review of experiences and needs. Asia Pac J Health
Manage. 2013. 8(1): 14-23.
Lee N, Mårtensson LB, Homer C, Webster J, Gibbons K,
Stapleton H, Dos Santos N, Beckmann M, Gao Y, Kildea S.
Impact on Caesarean section rates following injections of
sterile water (ICARIS): a multicentre randomised controlled
trial. BMC Preg Childbirth 2013, 13:105.
Dawson A, Homer CSE. How does the mining industry
contribute to sexual and reproductive health in developing
countries. J Clin Nurs 2013; 22 (23-24): 3597–3609.
Farrokh-Eslamlou H, Eslamli M, Aghlmand S, Homer CSE.
The impact of World Health Organization’s DecisionMaking Tool for Family Planning Clients and Providers on
the Quality of Family Planning Services in Iran. J Fam Plan
Reprod Health Care 2013;0:1–7.
Gray JE, Leap N, Sheehy A. Students’ perceptions of
the follow-through experience in three year Bachelor
of Midwifery Programs in Australia. Midwifery 2013;29,
400–406.
Halliday L, Sullivan E, Peek M, Ellwood D, Homer CSE,
Knight M, McLintock C, Jackson-Pulver L. The Australasian
Maternity Outcomes Surveillance System (AMOSS):
An evaluation of stakeholder engagement, usefulness,
simplicity, acceptability, data quality and stability. Aust N Z
J Obstet Gynaecol 2013;53(2):152-7.
Hammond A, Foureur M, Homer CSE, Davis D. Space,
place and the midwife: Exploring the relationship between
the birth environment, neurobiology and midwifery
practice. Women Birth 2013; 26(4): 277-281.
Henry A, Madan A, Reid R, Tracy SK, Austin K, Welsh AW,
Challis D. Outpatient Foley catheter versus inpatient
prostaglandin E2 gel for induction of labour: a randomised
trial. BMC Preg Childbirth 2013, 13:25.
Henry A, Shand A, Welsh AW. The short term fetal
cardiovascular effects of corticosteroids used in obstetrics.
Austral J Ultrasound Med 2013; 16: 128-134.
Homer CSE, Besley K, Bell J, Davis D, Adams J, Porteous
A, Foureur M. Does continuity of care impact decision
making in the next birth after a caesarean section (VBAC)?
A randomised controlled trial [Trial Protocol]. BMC Preg
Childbirth 2013,13:140.
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Listijono DR; Chapman MG; Boylan T; Cooke S; Kilani S.
An analysis of the impact of embryo transfer difficulty on
live birth rates, using a standardised grading system. Hum
Fertil (Camb). 2013; 16(3): 211-4.
McLindon LA; Beckmann M; Flenady V; McIntyre HD;
Chapman M. Women’s views of a fertility awareness and
hormonal support approach to subfertility. Hum Fertil
(Camb). 2013;16:252-7.
Raymond J, Smith RM, Gray JE, Homer CSE. Learning
through authentic assessment: an evaluation of a new
development in the undergraduate midwifery curriculum.
Nurse Educ Pract 2013;13(5): 471–476.
Richter J, Henry A, Ryan G, DeKonninck P, Lewi L, Deprest
J. Amniopatch procedure after previable iatrogenic
rupture of membranes: a two centre review. Prenat Diagn
2013; 33(4): 391-6.
Russell P, Sacks G, Tremellen K, Gee A The distribution
of immune cells and macrophages in the endometrium
of women with recurrent reproductive failure: Further
observations and reference ranges. Pathology. 2013;
45:393-401
Sanderson J, Wu L, Mahajan A, Meriki N, Henry A, Welsh
A. Selection of the Sub-Noise Gain level for acquisition of
VOCAL datasets: a reliability study. Ultrasound Med Biol
2013; DOI: 10.1016/j.ultrasmedbio.2013.09.004.
Shaban I, Hatamleh, R, Homer CSE. Evaluating the
Experience of Jordanian Women with Maternity Care
Services. Health Care Women Int 2013;34(6):499-512.
Sheehy A, Davis D, Homer CSE. Assisting women to
make informed choices about screening for Group B
Streptococcus in pregnancy: A critical review of the
evidence Women Birth 2013;26: 152–157.
Teate A, Leap N, Homer CSE. Midwives’ experiences of
becoming CenteringPregnancy facilitators: A pilot study in
Sydney, Australia. Women Birth 2013; 26(1): e31–e36.
Tracy SK, Hartz DL, Tracy MB, Kildea S, Allen Y, Forti A,
Hall B, Lainchbury A, Stapleton H, Beckmann M, Bisits
A; Homer CSE, Foureur M, White J, Welsh A. Caseload
midwifery care for women of all risk compared to standard
hospital care: a randomized controlled trial. (Midwives
@ New Group practice Options: M@NGO trial.) Lancet
2013;382 (9906): 1723 – 1732
Vallely, LM Homiehombo P, Kelly AM, Vallely A, Homer
CSE, Whittaker, A. Exploring women’s perspectives
of access to care during pregnancy and childbirth: A
qualitative study from rural Papua New Guinea. Midwifery
2013;29(10):1222-9.
Other Published Material
Atchan M, Homer CSE. (2013) Routine care of postpartum
women. In J. Abbott, L Bowyer, M Finn [Eds]. Obstetrics
and Gynaecology: An Evidence-Based Guide. Elsevier
Australia [219-230].
Henry A. Chapter 13. Infections in pregnancy. In: Abbott
J, Bowyer L, Finn M (eds). Ot. Elsevier Australia 2013.
Presentations at Scientific Meetings and
Conferences
2012 - International
Chapman MG. Corifollitropin Alfa – IVF Australia’s First 100
Cases FSA Meeting, Auckland, New Zealand, 2012
Chapman MG. Invited Speaker: Selection of the best
oocyte. Midwestern Reproductive Symposium, Chicago,
IL, USA, 2012
Homer CSE. (2012). Unravelling evidence based practice in
policy and reality – local, national, and international stories
from the field. Invited keynote speaker at Celebrating
Success: Turning best practice into common practice in
maternal and infant health and care, University of York, UK.
Homer CSE, Lees T, Stowers P, Aiavao F, Sheehy A,
Barclay LM. (2012) Traditional birth attendants in Samoa:
Integration with the formal health system. ICM Asia Pacific
Conference, Vietnam.
Meriki N, Henry A, Welsh AW. Development of normal
gestational ranges for the right myocardial performance
index in the Australian population with 3 alternative caliper
placements. Ultrasound in Obstetrics and Gynaecology
2012; 40 (Suppl 1): 137.
Welsh AW, Meriki N, Henry A. The ‘Delta-MPI’: a new
measure for unilateral fetal myocardial strain and its
normal gestational range. Ultrasound in Obstetrics and
Gynaecology 2012; 40 (Suppl 1): 138
Davis GK, Roberts LM, Mangos G, Brown MA. The UM101 mercury-free sphygmomanometer: a replacement for
mercury sphygmomanometry at last? Biennial Scientific
Meeting ISSHP 2012, Geneva (Poster)
2012 - National
Chen L, Gardiner A, Austin K, Kidson-Gerber G, Henry
A. Iron sucrose infusion in pregnancy. RANZCOG Annual
Scientific Meeting, Canberra, 2012.
Davis GK, Roberts LM, Mangos G, Brown MA. The UM101 mercury-free sphygmomanometer: a replacement for
mercury sphygmomanometry at last? Society of Obstetric
Medicine of Australia and New Zealand. Annual Scientific
Meeting. Sydney 2012.
Dilgir S, Parkin K, Patton V, Lubowski D, Karantanis E.
Predictive factors for Obstetric Anal Sphincter Injury. IUGA
ASM Brisbane 2012.
Everitt L, Homer C, Fenwick J. Midwives Experience of
Working with Community Services during Assumption
of Care of Newborns. Breathing New Life into Maternity
Care: Working together: balancing risk in maternity care.
Melbourne 2012.
Everitt L, Lock K, Fenwick J, Homer C. Breastfeeding and
assumption of care of newborns. The Inaugural Lactation
Consultants of Australia and New Zealand (LCANZ)
Conference. Sydney 2012.
Everitt, L. Learning to play the hard course: Midwives role
in assumption of care of newborns. Australian College
Midwives – NSW Branch Inc. Annual State Conference,
Playing the Course: A Round in Midwifery. Wyong 2012.
Hayes W, O’Toole J,Thakkar A, Moore K, Karantanis E.
Randomised Control Trial of Electromagnetic Chair versus
PElvic Floor Physiotherapy for women with stress urinary
incontinence. IUGA ASM 2012 Brisbane.
Homer CSE, Foureur M. The Potential Epigenetic Impact
of Peripartum Events and Long-term Cardiovascular
Health. Invited speaker at the Royal Hospital for Women
Annual Symposium: Celebrating 100 years of Antenatal
Care, Sydney 2012.
Homer CSE, Sandall J, Nicholl M, Redshaw M. Designing
a woman centered maternity service – balancing safety,
cost, geography and reality. Invited full day workshop
at Breathing New Life into Maternity Care, 4th Biennial
Conference. Melbourne 2012.
Homer CSE. The Homebirth consortium study. Place
of Birth and Models of Care Conference. University of
Western Sydney, 2012.
Roberts LM. What’s new in recording blood pressure
in pregnancy? St George Hospital Midwifery Seminar:
Working Together. Sydney 2012.
123
Chapman MG. Polarised light microscopy in oocyte
selection RANZCOG CREI Annual Meeting, Sydney, 2012
and Gynaecology RANZCOG Annual Scientific Meeting,
Sydney, 2013 (e-poster).
Chapman MG. Current Concepts on assisted reproduction
and fertility preservation ESA-SRB Meeting, Gold Coast,
2012
Chapman MG. Invited Speaker: Preparing for retirement.
RANZCOG ASM, Sydney, 2013.
2013 - International
Henry A, Welsh AW. Monitoring cholestasis of pregnancy
using the fetal modified myocardial performance index
(mod-MPI). 23rd World Congress on Ultrasound in
Obstetrics and Gynecology, Sydney, 2013.
Henry A, Meriki N, Mahajan A, Sanderson J, Wu L, Welsh
AW. Delta-MPI in pathological versus uncomplicated
pregnancies: a value-add to right and left mod-MPI?
23rd World Congress on Ultrasound in Obstetrics and
Gynaecology, Sydney 2013.
Henry A, Shand A, Crowther C, Palmer A, Wang YA, Welsh
AW. Comprehensive ultrasound evaluation of short-term
fetal effects of dexamethasone and betamethasone.
23rd World Congress on Ultrasound in Obstetrics and
Gynaecology, Sydney, 2013.
Homer C, Brodie P, Copeland F, Rumsey M, Dawson A. We
kam longwe so far: Building midwifery capacity in Papua
New Guinea. Pacific Society for Reproductive Health
Conference, July Apia, Samoa 2013.
Kanade T, Kulkarni S A, Sheregar N. Laparoscopic
management of grade IV endometriosis – TRICKS OF
TRADE. 41st Annual Conference of Mumbai Obstetrics
and Gynaecologic Society (MOGS). Juhu, Mumbai 2013.
Meriki N, Henry A, Sanderson J, Mahajan A, Wu L, Welsh
AW. Normal ranges for the right modified myocardial
performance index (RMPI) in the Australian population
using three alternative caliper placements. 23rd World
Congress on Ultrasound in Obstetrics and Gynaecology,
Sydney, 2013.
Chapman MG. Guideline preparation. RANZCOG CREI
Annual Meeting, Sydney, 2013.
Chwah S, Reilly A, Hall B, Henry A. Midwifery-led
intervention group for pregnant women of high body
mass index: engagement with and outcomes of SSWInG.
RANZCOG Annual Scientific Meeting, Sydney, S2013
(e-poster).
Everitt L, Homer C, Fenwick J. Assumption of care of a
newborn: How can you be prepared? Australian College
of Midwives 18th Biennial Conference, October, Hobart,
Australia. Abstract published in Women Birth 2013;26:
S1: S6.
Hammond A, Foureur M, Homer C, Davis D. The hospital
birth environment: Impacts on midwifery practice during
labour and birth. Australian College of Midwives 18th
Biennial Conference, October, Hobart, Australia. Abstract
published in Women Birth 2013;26:S1: S8.
Henry A, Lees N, Bein K, Hall B, Lim V, Chen K, Welsh A,
Hui L, Shand AW. Pregnancy outcomes before and after
institution of specialised Twins Clinic Care. RANZCOG
2013 Annual Scientific Meeting, Sydney, 2013.
Homer C, Rumsey M, Brodie P, Dawson A, Copeland F,
Daly J. (2013). Helping build foundations to improved
maternal health in PNG. International Council of Nurses
25th Quadrennial Congress, Melbourne 2013.
Homer C. Connections, Continuity and Community:
Models of care for Aboriginal and Torres Strait Islander
women. Perinatal Society of Australia and NZ 17th Annual
Congress. April, Adelaide, Australia. Abstract published in
J Paed Child Health 2013;49:S2: 7.
O’Connor M. Sexual Violence as a Weapon in Armed
Conflict. 40th World Congress of Military Medicine.
Jeddah. Kingdom of Saudi Arabia, 2013.
King K, Foo J, Henry A. Third trimester ultrasound:
an audit of current practices at St George Hospital.
RANZCOG Annual Scientific Meeting, Sydney, 2013.
Chapman MG. Invited Speaker: Other Than Kangaroos,
Does Australia Have Anything to Offer In Reproduction?
Midwestern Reproductive Symposium, Chicago, IL, USA,
2013.
Kruske S, Schmied V, Homer C. Midwives confidence
in the skills required for postnatal care: Results of a
national survey. Australian College of Midwives 18th
Biennial Conference, October, Hobart, Australia. Abstract
published in Women Birth 2013;26:S1: S11.
2013 - National
Austin K, Chambers G, Susic D, Madan A, De Abreu
Lourenco R, Henry A. Cost Effectiveness of induction of
Labour at term with inpatient vaginal prostaglandin E2
gel compared to an outpatient Foley Catheter (FOG Trial).
Royal Australian and New Zealand College of Obstetrics
124
Moody T, Fenwick J, Foureur M, Homer C, Davis D
Exploring ‘domesticity’ in the birthspace. Australian
College of Midwives 18th Biennial Conference, October,
Hobart, Australia. Abstract published in Women Birth
2013;26:S1: S14.
O’Connor M. Legal Protection for ADF Medical Officers in
a Quasi Authoritarian Organisation. NSW Military Health
Lecture, Randwick Barracks 2013
Raymond J, Homer C, Davis D. The Who, What and
Why: Weight management support for obese women
during pregnancy. Australian College of Midwives 18th
Biennial Conference, October, Hobart, Australia. Abstract
published in Women Birth 2013;26:S1: S15.
Pettit F, Davis G, Henry A, Mangos G, Brown MA. Is early
onset pre-eclampsia worse for mother or baby? Perinatal
Society of Australia and New Zealand Annual Scientific
Meeting, Perth, 2013.
Psaila K, Schmied V, Kruske S, Homer C. Transition of care:
how well is it done? Findings from the CHoRUS study.
Australian College of Midwives 18th Biennial Conference,
October, Hobart, Australia. Abstract published in Women
Birth 2013;26:S1: S18.
Whitton K, Shand A, Pasfield A, Nassar N, McShane M,
Han X, Henry A. Anti-Mullerian hormone: a predictor
of adverse pregnancy events? PSANZ Annual Scientific
Meeting, Adelaide, 2013.
125
Nursing and
Midwifery
Centre for Research in
Nursing and Health
>
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Centre for Research in Nursing and Health
Director of Nursing and Midwifery
Vicki Manning RN, BAdmin (Nursing), MPH
Centre for Research in Nursing and Health
Professor Ritin Fernandez RN, PhD School of Nursing and
Midwifery - University of Wollongong St George Hospital
Daniela Levido (Stomal Therapy Clinical Nurse Consultant,
Graduate Certificate in Stomal Therapy, BN)
Suzanne Polis (BN, MPH by research, Post grad certificate
in Gastroenterology & Hepatology, PhD candidate)
Megan Higgs (BN, MN, PhD candidate)
Research Grants
Craig D, Fernandez R (2013) Clinical Management of
Chinese speaking women with Gestational Diabetes
Mellitus speaking women with Gestational Diabetes. St
George Hospital: Multicultural Health Service Cultural
Diversity Health Enhancement Grants Program 20122013. $6,800
Curtis K, Foster K, Mitchell R (2013) Paediatric Critical
Injury Research Program (6 years). South Eastern Sydney
Local Health District (SESLHD): Day of Difference. 574,223
Curtis K, Goldsmith H, Langcake M (2013) Improving
outpatient pain management. South Eastern Sydney Local
Health District (SESLHD): Motor Accidents Authority of
NSW. $13, 676
Curtis K, Murphy M, Hardy J, Lewis M, Strachan L, Buckley
DT (2012) Evaluation of an emergency nursing assessment
framework on patient assessment and documentation:
A pilot study South Eastern Sydney Local Health District
(SESLHD): Emergency Care Institute. $99,457.60
Curtis K, Roberts L, Langcake M (2013) Improving the care
and outcomes of patients with blunt chest injury. South
Eastern Sydney Local Health District (SESLHD): Motor
Accidents Authority of NSW. $14,814
Falomir C (2013) Cancer Information CALD Wall and
DVD library. South Eastern Sydney Local Health District
(SESLHD): Multicultural Health Service Cultural Diversity
$1800
Fernandez R (2012) Secondary prevention following PCI.
128
South Eastern Sydney Local Health District (SESLHD):
University of Wollongong $20,000
Fernandez R, Arthur B (2013) Dementia education for
acute care nurses: NSW Ministry of Health, Dementia
Training Study Centres $50,000
Fernandez R, Higgs M (2013) Perception of cardiovascular
risk among offsprings of people with acute coronary
syndrome. South Eastern Sydney Local Health District
(SESLHD): University of Wollongong $5000
George R, Straube B, Cook C, Gallard J, et al. (20132015) Enhancing Intravenous Cannula Care by Patients
from Culturally and Linguistically Diverse Backgrounds
(ENABLE). SESLHD: Multicultural health service, Cultural
Diversity Health Enhancement Grants $5,000
Murray N, Griffith J (2012) Arabic Centering in Pregnancy.
South Eastern Sydney Local Health District (SESLHD):
Multicultural Health. $8511
Matthews L, Griffith J (2012) Ways of Working (WOW).
Maternity Services, St George Hospital: Nurse & Midwifery
Office Strategy $16,192
Polis S (2013) Adherence to Hepatitis B anti-viral
medications. St George Hospital: Gilead Sciences. $13,000
Polis S, Pritchard -Jones J (2013) Education needs of
hepatology nursing staff working with patients diagnosed
with HCV and HBV related advanced liver disease. St
George Hospital: Pillar Award for Nursing & Allied Health.
Roche Pharmaceuticals. $10,000
Polis S, Zekry A, Fernandez R (2013) Effect of a nurse
directed model of outpatient care for management
of patients with advanced liver disease: a pilot study
St George Hospital: St George & Sutherland Medical
Research Foundation. $20,000
Ho S, Cook C, Straube B, Fernandez R, et al. (2013-2014)
The Action Study: Strategies to reduce the VRE infection
(Transmission and BacteraemIa) rates in high risk patients
admitted to 4E/4N wards. SESLHD: SESLHD Infection
Prevention & Control Enhancement Program. $100,000
Wiseman T, Curtis K, West S (2013) E-learning to improve
trauma care on the wards. South Eastern Sydney Local
Health District (SESLHD): Motor Accidents Authority of
NSW. $14, 717.
Original Peer Reviewed Publications
Asha S, Curtis KA, Grant N, Taylor C, Lo S, Smart R,
Compagnoni K (2012) Comparison of radiation exposure
of trauma patients from diagnostic radiology procedures
before and after the introduction of a panscan protocol.
Emergency Medicine Australasia 24:43-51.
Asha SE, Ajami A (2013) Improvement in emergency
department length of stay using an early senior medical
assessment and streaming model of care: A cohort study.
Emergency Medicine Australasia 25:445-451.
Asha SE, Curtis KA, Taylor C, Kwok A (2013) Patientcontrolled analgesia compared with interval analgesic
dosing for reducing complications in blunt thoracic
trauma: a retrospective cohort study. Emergency Medicine
Journal 30:1024-1028.
Blay N, Glover S, Bothe J, Lee S, Lamont F (2012)
Substance users’ perspective of pain management in the
acute care environment. Contemporary Nurse 42:289-297.
Brown MA, Roberts LM, Mackenzie C, Mangos G, Davis
GK (2012) A prospective randomized study of automated
versus mercury blood pressure recordings in hypertensive
pregnancy (PRAM Study) Hypertension in Pregnancy
31:107-119.
Burns T (2013) Waiting for a kidney transplant in Australialatest trends. Transplant Journal of Australasia 22:10.
Burns T (2013) Nutritional Management of Renal Disease.
Renal Society of Australasia Journal 9:143.
Clements A, Curtis K (2012) What is the impact of nursing
roles in hospital patient resuscitation? Australasian
Emergency Nursing Journal 15:108-115.
Clohessy P, Polis S, Post J (2013) Spontaneous clearance
of hepatitis C virus during pregnancy. Obstetric Medicine:
The Medicine of Pregnancy 6:28-29.
Connell T, Fernandez RS, Tran D, Griffiths R, Harlum J,
Agar M (2013) Quality of life of community-based palliative
care clients and their caregivers. Palliative Support Care
11:323-330.
Cuesta C, Blow T, Tranter S (2013) Epidermolysis bullosa: a
rare challenge for peritoneal dialysis nurses. Renal Society
of Australasia 9:41-44.
Curtis K, Caldwell E, Delprado A, Munroe B (2012)
Traumatic injury in Australia and New Zealand. Australasian
Emergency Nursing Journal 15:45-54.
Curtis K, Chan DL, Lam MK, Mitchell R, King K, Leonard
L, D’Amours S, Black D (2013) The injury profile and
acute treatment costs of major trauma in older people in
New South Wales. Australasian Journal on Ageing. DOI:
10.1111/ajag.12059
Curtis K, Leonard E (2012) The Trauma Nurse Coordinator
in Australia and New Zealand: Demographics, Role, and
Professional Development. Journal of Trauma Nursing
19:214-220.
Curtis KA, Mitchell RJ, Chong SS, Balogh ZJ, Reed DJ,
Clark PT, D’Amours S, Black DA, Langcake ME, Taylor CB
(2012) Injury trends and mortality in adult patients with
major trauma in New South Wales. Medical Journal of
Australia 197:233.
Dinh MM, Curtis K, Ivers R (2013) The effectiveness of
helmets in reducing head injuries and hospital treatment
costs: a multicentre study. Medical Journal of Australia
198:415, 417.
Dinning PG, Hunt LM, Arkwright JW, Patton V, Szczesniak
MM, Wiklendt L, Davidson JB, Lubowski DZ, Cook IJ
(2012) Pancolonic motor response to subsensory and
suprasensory sacral nerve stimulation in patients with slowtransit constipation. British Journal of Surgery 99:10021010.
Dinning PG, Wiklendt L, Gibbins I, Patton V, Bampton P,
Lubowski DZ, Cook IJ, Arkwright JW (2013) Low-resolution
colonic manometry leads to a gross misinterpretation of
the frequency and polarity of propagating sequences:
Initial results from fiber-optic high-resolution manometry
studies. Neurogastroenterology Motility 25:e640-649.
Dunford M, ACI-ICCMU Tracheostomy Expert Group
(2013) Care of Adult Patients in Acute Care Facilities with a
Tracheostomy Clinical Practice Guideline. Sydney: Agency
for Clinical Innovation.
Dutton M, Curtis K (2012) Well-wound therapy: use of
Negative Pressure Wound Therapy to prevent laparotomy
breakdown. Journal of Wound Care 21(8) 386-388
Everett B, Salamonson Y, Trajkovski S, Fernandez R (2013)
Demographic and academic-related differences between
129
standard-entry and graduate-entry nursing students: A
prospective correlational survey. Nurse Education Today
33:709-713.
Everitt L (2013) Collaboration matters: Working with
‘chaotic’ complex women: A case study. Midwifery Matters
Newsletter of the Australian College of Midwives-NSW
Branch Incorporated 32:14-15.
Everitt L (2013) The experiences of midwives working with
the removal of newborns for child protection concerns in
NSW, Australia: Being in the headspace and heart space.
UTS Digital Theses Collection 1-133.
Everitt L (2013) Research Matters: Assumption of care of
newborns in maternity units. Midwifery Matters Newsletter
of the Australian College of Midwives-NSW Branch
Incorporated 32:10-11.
Fernandez R, Griffiths R (2012) Water for wound
cleansing. Cochrane Database Syst Rev 15 DOI
101002/14651858CD003861pub3.
Fernandez R, Johnson M, Tran DT, Miranda C (2012)
Models of care in nursing: a systematic review.
International Journal of Evidence Based Health Care
10:324-337.
Fernandez R, Rajaratnam R, Evans K, Speizer A (2012) Goal
setting in cardiac rehabilitation: implications for clinical
practice. Contemporary Nurse 43:13-21.
Fernandez R, Salamonson Y, Griffiths R (2012) Emotional
intelligence as a predictor of academic performance in
first-year accelerated graduate entry nursing students.
Journal of Clinical Nursing 21:3485-3492.
Fernandez RS, Frost S (2013) Congruence between the
Indian Diabetes Risk Score and Australian Type 2 Diabetes
Risk Assessment tool screening in Asian-Indians. Nurse
Researcher 21:36-39.
Fernandez RS, Tran DT, Ramjan L, Ho C, Gill B (2012)
Comparison of four teaching methods on Evidence-based
Practice skills of postgraduate nursing students. Nurse
Education Today Online early view.
Fry M, MacGregor C, Ruperto K, Jarrett K, Wheeler J,
Fong J, Fetchet W (2013) Nursing praxis, compassionate
caring and interpersonal relations: An observational study.
Australasian Emergency Nursing Journal 16:37-44.
Fry M, Ruperto K, Jarrett K, Wheeler J, Fong J, Fetchet
W (2012) Managing the wait: Clinical initiative nurses’
perceptions of an extended practice role. Australasian
Emergency Nursing Journal 15:202-210.
Frydenberg E, Curtis K, Chong S, Poulos R, Grzebieta R,
Steel T, Nau T (2012) Road trauma, patterns of injury and
mortality in an Australian trauma centre. Journal of the
Australasian College of Road Safety 23:21.
Graham J, Gallagher R, Bothe J (2013) Nurses’ discharge
planning and risk assessment: behaviours, understanding
and barriers. Journal of Clinical Nursing 22:2338-2346.
Hawkins TA, Roberts J, Mangos G, Davis G, Roberts L,
Brown M (2012) Plasma uric acid remains a marker of
poor outcome in hypertensive pregnancy: a retrospective
cohort study. British Journal of Obstetrics & Gynaecology:
An International Journal of Obstetrics & Gynaecology
119:484-492.
Josland E (2013) Quality of Life. What information is
already available and what evidence is this based on?
Nephrology On Line early view DOI: 10.1111/nep.12072.
Josland E, Brennan F, Anastasiou A, Brown MA (2012)
Developing and sustaining a renal supportive care service
for people with end-stage kidney disease. Renal Society of
Australasia Journal, 8 (1) 12-18.
Josland E (2013) Book review Kidney disease: From
advanced disease to bereavement. Second edition. The
Renal Society of Australasia Journal 9:142.
Mahashabde R, Fernandez R, Sabnis S (2013) Validity
and reliability of the aneroid sphygmomanometer using
a paediatric size cuff for craniocervical flexion test.
International Journal of Evidence‐Based Healthcare
11:285-290.
Feild D (2013) Book Review: Understanding chronic kidney
disease a guide for non-specialists. Renal Society of
Australasia Journal 9:45.
McIntosh AS, Curtis K, Rankin T, Cox M, Pang T, McCrory
P, Finch C (2013) Associations between helmet use and
brain injuries amongst injured pedal-and motor-cyclists: A
case series analysis of trauma centre presentations. Journal
of the Australasian College of Road Safety 24:11.
Fry M, Horvat L, Roche M, Fong J, Plowes J (2012) The
prevalence and triage characteristics of patients presenting
with infection to one tertiary referral hospital. Australasian
Emergency Nursing Journal 15:127-132.
Mitchell R, Curtis K, Fisher M (2012) Understanding Trauma
as a Men’s Health Issue: Sex Differences in Traumatic Injury
Presentations at a Level 1 Trauma Center in Australia.
Journal of Trauma Nursing 19:80-88.
Fry M, Horvat L, Roche M, Fong J, Plowes J (2013) A
four month prospective descriptive exploratory study
of patients receiving antibiotics in one Emergency
Department. International Emergency Nursing 21:163-167.
Mitchell R, Watson WL, Curtis K, Harris I, McDougall
P (2012) Difficulties in establishing long-term trauma
outcomes data collections. Could trauma outcomes
be routinely monitored in New South Wales, Australia:
130
Piloting a 3 month follow-up? Injury 43:96-102.
Mitchell RJ, Curtis K, Chong S, Holland AJ, Soundappan
S, Wilson KL, Cass DT (2013) Comparative analysis of
trends in paediatric trauma outcomes in New South Wales,
Australia. Injury 44:97-103.
Mitchell RJ, Curtis K, Holland AJ, Balogh ZJ, Evans J,
Wilson KL (2013) Acute costs and predictors of higher
treatment costs for major paediatric trauma in New South
Wales, Australia. Journal of Paediatrics and Child Health
49:557-563.
Moore S (2013) Management of multi-resistant organisms
(MRO) in the perioperative environment study tour.
ACORN: The Journal of Perioperative Nursing in Australia
26:18.
Morris P (2013) Understanding the experience of a
cancer diagnosis and illness--A patient perspective of the
biographical disruption of multiple myeloma. Australian
Journal of Cancer Nursing 14:20.
Moustakas J, Bennett P, Tranter S, Nicholson J (2012)
The needs of older people with advanced chronic kidney
disease choosing supportive care: a review. The Renal
Society of Australasia Journal 8:70-75.
Munroe B, Curtis K, Considine J, Buckley T (2013) The
impact structured patient assessment frameworks have
on patient care: an integrative review. Journal of Clinical
Nursing 22:2991-3005.
Ogilvie R, McCloughen A, Curtis K, Foster K (2012) The
experience of surviving life‐threatening injury: a qualitative
synthesis. International Nursing Review 59:312-320.
Patton V, Wiklendt L, Arkwright JW, Lubowski DZ, Dinning
PG (2013) The effect of sacral nerve stimulation on distal
colonic motility in patients with faecal incontinence. British
Journal of Surgery 100:959-968.
heterogeneity of Australian nursing students: a closer look.
International Nursing Review 59:59-65.
Sorensen R, Paull G, Magann L, Davis J (2013) Managing
between the agendas: implementing health care reform
policy in an acute care hospital. Journal of Health
Organization and Management 27:698-713.
Taylor C, Jan S, Curtis K, Tzannes A, Li Q, Palmer C,
Dickson C, Myburgh J (2012) The cost-effectiveness of
physician staffed Helicopter Emergency Medical Service
(HEMS) transport to a major trauma centre in NSW,
Australia. Injury 43:1843-1849.
Taylor CB, Curtis K, Jan S, Newcombe M (2013) Helicopter
Emergency Medical Services (HEMS) over-triage and the
financial implications for major trauma centres in NSW,
Australia. BMC Emergency Medicine 13:11.
Tranter S, Anastasiou A, Bazzi H, Burgess H, Josland
E (2013) The renal memorial service: an important
component of renal supportive care. Renal Society of
Australasia Journal 9:80-84.
Wang DH, Blenman N, Maunder S, Patton V, Arkwright
J (2013) An optical fiber Bragg grating force sensor for
monitoring sub-bandage pressure during compression
therapy. Optics Express 21:19799-19807.
Westgarth F, Chiarella M, Tranter S (2012) The
haemodialysis Models of care Program. The Renal Society
of Australasia Journal 8:24-31.
Willenberg L, Curtis K, Taylor C, Jan S, Glass P, Myburgh
J (2012) The variation of acute treatment costs of trauma
in high-income countries. BMC Health Services Research
12:267.
Wiseman T, Foster K, Curtis K (2013) Mental health
following traumatic physical injury: An integrative literature
review. Injury 44:1383-1390.
Presentations at Conferences and Meetings
Pianta TJ, Horvath AR, Ellis VM, Leonetti R, Moffat C,
Josland EA, Brown MA (2012) Cardiac high‐sensitivity
troponin T measurement: A layer of complexity in
managing haemodialysis patients. Nephrology 17:636641.
Abraham E, Patton V, Lutton N, Lubowski D (2012) The
cutting seton. Annual Scientific Congress, RACS Kuala
Lumpur, Malaysia.
Rolley J, Fernandez R, Everett B, Mohan S, Davidson PM
(2012) Factors associated with dietary practices and heart
disease prevention among Indian Australians: a focus
group study. Heart, Lung and Circulation 21:S308.
Abraham E, Patton V, Lutton N, Lubowski D (2012) Sacral
nerve stimulation for faecal incontinence - our institution’s
experience. Annual Scientific Congress, RACS Kuala
Lumpur, Malaysia.
Rolley J, Fernandez R, Everett B, Mohan S, Davidson PM
(2012) Perceptions of medication taking among Asian
Indian Australians: a focus group study. Heart, Lung and
Circulation 21:S312.
Ajami A (2012) The First Aid Skills Training (FAST) Project.
Multicultural health research to practice forum: St George
Hospital, NSW.
Salamonson Y, Ramjan L, Lombardo L, Lanser LH,
Fernandez R, Griffiths R (2012) Diversity and demographic
Ajami A, Chan DT (2012) Medical Assessment and
Decision Making in Emergency (MADMEN) Project.
Australasian Redesigning Healthcare Summit, Brisbane.
131
Awad S, Cooper N, Department E (2013) ED Versus the
Ward. Can secondments improve clinician relationship
and development of knowledge and skills. Council
of Children’s Nurses Conference: Winds of Change:
Homebush, NSW.
Curtis K (2013) Keynote speaker 8th Annual Critical Care
Conference Vineyards, Hunter Valley, NSW.
Curtis K (2012) 2012 Vision, Challenges, and New Frontiers
in Emergency Care. 10th International Conference for
Emergency Nursing: Hobart.
Brown M, Collett G, Josland E, Brennan B (2013) Nondialysis management in the elderly: survival, sympton
control and quality of life. ASN Kidney Week: Atlanta
Georgia USA. Burns, L (2012)
Curtis K (2013) Management of massive haemorrhage in
trauma. International Conference for Emergency Nurses:
Melbourne.
Burns, L (2012) Minimal Space, No Extra Nurses but Lots
of Patients – Finding a New Way to Increase Capacity.
Haematological Society of Australia and New Zealand,
Melbourne November.
Curtis K, Chan D (2013) . The injury profile and acute
treatment costs of major trauma in older people in
New South Wales. Trauma Surgery Section of the Royal
Australasian College of Surgeons Annual Scientific
Congress: Auckland, New Zealand.
Burns, L (2012) Minimal Space, No Extra Nurses but Lots
of Patients – Finding a New Way to Increase Capacity.
(Presentation & Poster) National Health Roundtable
Innovation Awards, October 2012. Sydney, Australia
(Winner of National Innovator of the year, nominated for a
Premier’s award 2012).
Burns L, Morris K (2012) Improving the Cancer Journey –
Introduction of a Nurse-Run Clinic for Patients Finishing
Treatment for Cancer. The Annual Scientific Meeting of the
HAA (Haematology Society of Australia and New Zealand,
HSANZ, the Australian & New Zealand Society of Blood
Transfusion, ANZSBT, and the Australasian Society of
Thrombosis and Haemostasis - ASTH) and the Asian-Pacific
Society on Thrombosis and Haemostasis: Melbourne
Burns T, Fernandez R, Stephens M (2013) Waiting for a
kidney transplant - a literature review. Transplant Nurses of
Australasia Annual Conference Sydney, NSW.
Chandrasekhar J, Paull G, Youssef G, Weaver J, Rees D
(2012) Single Centre Clinical Experience and Discharge
planning using high sensitivity troponin T post Elective
PCI. 60th Annual Scientific Meeting of Cardiac Society of
Australia and New Zealand Brisbane.
Cryer J.A (2012) Ten years on and still going strong.
International Cancer Nurses Conference: Prague.
Cuesta A, Tranter, S. & Blow, T (2012) Caring for a
patient with Epidermolysis Bullosa on Peritoneal Dialysis.
Renal Society of Australasia 40th Annual Conference:
Melbourne, VIC.
Cuesta A (2013) Addressing Peritoneal Dialysis Related
Infection. Nephrology workshop: Sydney, NSW.
Cuesta A, Tranter S, Blow T (2013) Taking control:
addressing peritoneal dialysis related infection outcomes.
Renal Society of Australasia Conference: Hobart.
Curtis K (2012) Invited speaker – case reviews. Swan XX
Trauma Conference: Sydney.
132
Curtis K, Clements A, Curtis K, Holzhauser K, Horvat L
(2012) The impact of a senior nurse as nurse team leader
on communication and perceptions of leadership in major
trauma resuscitations. Trauma 2012 Conference: Perth.
Curtis K, Clements A, Holzhauser K, Horvat L (2012)
The impact of a senior nurse as nurse team leader on
communication and perceptions of leadership in major
trauma resuscitations. 10th International Conference for
Emergency Nursing: Hobart.
Curtis K, Crouch R, Palfrey R, McHale H (2013) Trauma
Nurse Coordinators in England Major Trauma Coordinator
National Conference: Salford, England.
Curtis K, Dutton M, Chiarella M (2012) The current state
of knowledge into role, context of practice and impact of
the wound care nurse. 4th Congress of the World Union
of Wound Healing Societies Better Care, Better Life:
Yokohama Japan.
Curtis K, Dutton M, Chiarella M (2012) The current state
of knowledge into role, context of practice and impact of
the wound care nurse. 10th National Australian Wound
Management Association Conference: Sydney Convention
& Exhibition Centre.
Curtis K, Frydenberg E, Chong S, Poulos R, Grzebieta R,
Steel T, Nau T (2012) Road Trauma, Patterns of Injury and
Mortality in an Australian Trauma Centre. Neurosurgery
Section of the Royal Australasian College of Surgeons’
Annual Scientific Congress: Kuala Lumpur, Malaysia.
Curtis K, Kennedy B, Waters D (2013) The Personality
Characteristics of Emergency Nurses. International
Conference for Emergency Nurses: Melbourne.
Curtis K, Lam M, Mitchell R, Black D, al e (2012) Acute
costs and predictors of higher treatment costs of trauma
in New South Wales, Australia. Trauma 2012 Conference:
Perth.
Curtis K, Leonard E (2012) A snapshot: Resources currently
available in trauma services throughout Australia and New
Zealand. Trauma 2012 Conference: Perth.
Curtis K, Mitchell R, al. e (2013) Acute care costs and
predictors of higher treatment costs for major paediatric
trauma in NSW. 11th Australasian Injury Prevention &
Safety Promotion Conference: Fremantle, WA.
Curtis K, Mitchell RJ, Chong S, Balogh ZJ (2012) Injury
trends and mortality in adult patients with major trauma
in NSW. 10th International Conference for Emergency
Nursing: Hobart.
Curtis K, Mitchell RJ, Chong S, Balogh ZJ (2012) Injury
trends and mortality in adult patients with major trauma in
NSW. Trauma 2012 Conference: Perth.
Curtis K, Mitchell RJ, Chong S, Balogh ZJ (2013) Injury
trends and mortality in adult patients with major trauma
in New South Wales, Australia. Unlocking the Value of
Mortality Data Workshop: Sydney.
Curtis K, Munroe B, Curtis K, Buckley T, Considine J
(2012) The impact of a structured patient assessment on
patients and clinicians. 10th International Conference for
Emergency Nursing: Hobart.
Curtis K, Ogilvie R, Palmer C, Lam M, McCloughen
A, Foster K (2013) Incidence and outcomes of major
traumatic injury in the Australian Capital Territory.
Canberra Health Annual Research Meeting (CHARM):
Canberra, ACT.
Curtis K, Ogilvie R, Palmer C, Lam M, McCloughen
A, Foster K (2013) Incidence and outcomes of major
traumatic injury in the Australian Capital Territory.
International Conference for Emergency Nurses:
Melbourne.
Curtis K, Wiseman T, Foster K (2013) The incidence of
depression, anxiety and stress (DAS) in trauma patients
during hospital admission and 3 months post injury.
Queensland Trauma Symposium Brisbane, QLD.
Davis G, Roberts L, Mangos G, Brown M (2012) The UM101 mercury-free sphygmomanometer: a replacement for
mercury sphygmomanometry at last? XVIII ISSHP World
Congress: Geneva, Switzerland.
Decker V (2013) Regular Interprofessional Simulation
Cases. STG POWH ICU Symposium Sydney.
Dinning P, Patton V, Hunt L, Gebski V, Jones M, Stewart
P, Lubowski D, Cook I (2013) Efficacy of sacral nerve
stimulation for severe slow transit constipation -a
randomised double-blind placebo-controlled crossover
study. . American Society of Colon and Rectal Surgeons
Annual Meeting: Phoenix Arizona.
Everitt L (2012) Assumption of Care. St George /
Sutherland Hospitals & Health Services (SGSHHS) Annual
Midwifery Seminar Working Together: Kogarah.
Everitt L (2012) Learning to play the hard course: Midwives
role in assumption of care of newborns. Australian College
Midwives – NSW Branch Inc. Annual State Conference:
Wyong, NSW.
Everitt L, Homer C, Fenwick J (2012) Midwives Experience
of Working with Community Services during Assumption
of Care of Newborns. 4th Biennial Breathing New Life into
maternity Care Multidisciplinary Conference: Melbourne,
Victoria.
Everitt L, Homer C, Fenwick J (2013) Assumption of Care
of a Newborn: How can you be prepared? Australian
College of Midwives, 18th National Conference: Hobart,
Tasmania.
Everitt L, Lock K, Fenwick J, Homer C (2012) Breastfeeding
and assumption of care of newborns. . The Inaugural
Lactation Consultants of Australia and New Zealand
(LCANZ) Conference Sydney, NSW.
Griffith J (2012) Understanding 1:1 midwifery care. NSW
Health Towards Normal Birth State-wide Workshop:
Sydney, NSW.
Griffith J (2013) Rural maternity: what’s so different? UTS
Bachelor of Midwifery (Year 3) Day: Sydney, NSW.
Griffith J, Best P (2012) Ways of Working in Maternity Care.
St George Midwifery Conference: Kogarah, NSW.
Griffith J, Best P (2012) Ways of Working in Maternity Care.
SESLHD Executive Forum: Randwick, NSW.
Hodges K, Jones S (2013) Multidisciplinary ward round
project. STG POWH ICU Symposium Sydney.
Davis S, Paull G, Vuong N, Connolly B, Ang E (2012)
ICD’s and PTSD: a shocking story - from crisis to recovery.
Australian Cardiovascular Health and Rehabilitation
Association Conference Kirribilli, NSW.
Horvat L, Fry M, Plowes J, Fong J (2012) To explore the
nursing assessment and initial management of septic
patients in the Emergency Department. Annual Critical
Care Conference Hunter Valley, NSW.
Davis S, Paull G, Vuong N, Connolly B, Ang E (2012)
ICD’s and PTSD: a shocking story - from crisis to recovery.
Australian Cardiovascular Health and Rehabilitation
Association Conference: Brisbane, QLD.
Jacques E (2012) HCC Nurse Coordinator: Impact on
MDT Model and Patient Education. 8th Australasian Viral
Hepatitis Conference: Auckland, NZ.
133
Jones S (2013) Pressure injury prevention for critically ill
patients Guidelines. The ACI Intensive Care Coordination
and Monitoring Unit (ICCMU): Sydney.
Josland E (2012) Hepatitis Protocols: Opening a can of
worms. RSA 40th Annual Conference: Melbourne, VIC.
Josland E (2012) Renal Supportive Care: Holistic care
for ESKD patients and their families. RSA 40th Annual
Conference: Melbourne, VIC.
Josland E, Collett G, Brennan F, Foote C, Brown M (2012)
HOPE: Helping Older People with ESKD. International
Forum on Quality and Safety in Healthcare: Le Palais des
Congress, Paris, France.
Keating L (2013) Measurement of temperature in critically
ill adults: A systematic review and clinical practice
guideline. . The Australian and New Zealand Intensive
Care Society (ANZICS) Conference: Hobart, Tasmania.
Keating P (2013) Manual Handling Equipment in St
George Hospital. Statina International Conference:
Homebush Sydney.
Keating P (2013) Perioperative Introduction Programme to
Tongan Nurses. Orthopaedic Outreach: Tonga.
Kennedy B (2013) Personality Characteristics of Emergency
Nurses College of Emergency Nursing Australasia (CENA)
Conference: Melbourne.
Lafferty M (2012) Improving care in RACF - a Model to
improve care and communication- NSW Palliative care
NSW Palliative Care Dubbo.
Lock K (2013) Vulnerable Population groups: Innovative
Models of Care at two Baby Friendly Health Accredited
hospitals. International Lactation Consultant Association
Conference: Melbourne, Victoria.
Magann L (2012) Benefits of early referral to palliative
care, symptom management and end of life conversations
Australian Hepatoly Summit: Sydney.
Martinez-Smith Y, Meek C (2012) “Collaboration in Care”.
Home Therapies Workshop: Sydney, NSW.
Martinez-Smith Y, Meek C (2012) Oral presentation –
“Collaboration in Care”. Home Therapies Workshop:
Sydney, NSW.
McCarthy F, Falomir C (2012) Solution to safe storage.
Innovation in work health and Safety: St George Hospital,
Sydney.
Meek C (2013) Safeguarding veins – the use of a Save
the Vein Tattoo. Renal Society of Australasia Annual
Conference: Hobart.
134
Meek C (2013) Transitioning onto Haemodialysis Evaluating the effectiveness of a new educational
resource. Renal Society of Australasia Annual Conference:
Hobart, TAS.
Modester T (2012) Fractured Neck of Femur. Australian
Orthopaedic Nurses’ Association Annual Conference:
Homebush, NSW.
Moore S (2012) Perioperative Management of
Patients with MROs Centre for Infectious Diseases and
Microbiology Public Health Conference Westmead
Hospital, Sydney Australia.
Moore S (2012) Understanding Health Fund Contracts.
Day Surgery Nurses Association State Conference: Sydney,
Australia.
Moustakas J, Bennett P, Tranter S, Nicholson J (2012)
Supportive care: what does the patient want? Renal
Society of Australasia 40th Annual Conference:
Melbourne, VIC.
Patton V (2012) Antegrade colonic enema administered via
Chait Cecostomy Catheter. World Council of Enterostomal
Therapists: Adelaide .
Patton V (2013 ) Are anorectal physiology tests useful in
asymptomatic primiparous patients with OASIS obstetric
anal sphincter injuries? Royal Australian and New Zealand
College of Obstetricians and Gynaecologists 2013 Annual
Scientific Meeting (RANZCOG 2013 ASM): Sydney, NSW.
Patton V, Dinning P, Lubowski DZ, Arkwright J, King
D (2012) Colonic manometry demonstrates the mode
of action of sacral nerve stimulation in patients with
faecal incontinence Joint International Meeting in
Neurogastroenterology and Motility Bolongna Italy.
Patton V, Lubowski D (2012) Sacral nerve stimulation
modifies colonic motility in patients with faecal
incontinence. International Society of University Colon and
Rectal Surgeon (ISUCRS) Congress: Bologna.
Patton V, Lubowski D (2013) Antegrade colonic enema via
a Chait caecostomy catheter - is it a viable option for adult
bowel management?, American Society of Colon and
Rectal Surgeons Annual Meeting: Phoenix Arizona.
Patton V, Lubowski D (2013) Sacral nerve stimulation for
slow transit constipation. St George Medical Research
Conference Sydney, NSW.
Patton V, Lubowski D (2013) Sacral nerve stimulation:
why do patients fail PNE? American Society of Colon and
Rectal Surgeons Annual Meeting: Phoenix Arizona.
Paull G (2012) Self-management: Multilingual Audio-visual
Resources for People with Ischaemic Heart Disease and
Chronic Heart Failure Australasian Cardiovascular Nursing
College, The Ageing Heart Conference: Sydney, NSW.
Paull G, Gallagher R, Horvath R, Chen D (2012)
Discrimination and high sensitivity cardiac troponin: the
relationship between clinical presentation, clinical request
and discharge diagnosis. 60th Annual Scientific Meeting
of Cardiac Society of Australia and New Zealand Brisbane,
QLD.
Polis S, Matisan A, Mainali B, al e (2012) Patient
adherence to lactulose to minimise the risk of Hepatic
Encephalopathy. 8th Australasian Viral Hepatitis
Conference Auckland, New Zealand.
escalation of delays in order to facilitate patient flow within
ED. Annual Critical Care Conference Hunter Valley, NSW
Romero B, Ajami A, Bayeh G, Neuhaus L, Foreshew M,
Cosgrove J (2012) To identify delay reasons for Ed patients
at 4 and 8 hours allowing the early identification and
escalation of delays in order to facilitate patient flow within
ED. Annual Critical Care Conference: Hunter Valley, NSW.
Polis S, Wheeler E, Richmond J (2012) Developing
Hepatitis B virus education for registered nurses.
Australasian Viral hepatitis Conference: Auckland, New
Zealand.
Sorensen R, Paull G, Magaan L, Davis J (2012) Is poor
quality of care built into the system? Evidence from a study
on communication among teams treating people dying
in hospital 8th International Organisational Behaviour in
Healthcare Conference - Patient-centred healthcare teams:
achieving collaboration, communication and care: Dublin,
Ireland.
Polis S, Wheeler E, Richmond J (2012) Evaluation
of Hepatitis B Virus education for registered nurses.
Australasian Viral hepatitis Conference: Auckland, New
Zealand.
Speizer A, Fernandez R (2012) Goal setting in cardiac
rehabilitation: Implications for clinical practice. The
Australian Cardiovascular Health and Rehabilitation
Association Conference Brisbane.
Polis S, Zekry A, Maher L (2012) Adherence to anti-viral
medications: a qualitative study. Australasian Viral hepatitis
Conference: Auckland, New Zealand.
Szwajcer A (2012) Supporting Young Women with Breast
Cancer. International Cancer Nurses Conference: Prague.
Reilly A, Everitt L, Murray N (2013) Young Mum’s Group:
Unexpected Lessons. Australian College of Midwives, 18th
National Conference: Life, Art and Science in Midwifery:
Hobart, Tasmania.
Roberts L (2012) Hypertension in pregnancy- practice
and evidence. Australian College of Midwives National
Webinar Series.
Roberts L, Davis G, Mangos G, Brown M (2012) The UM101 mercury-free sphygmomanometer: a replacement
for mercury sphygmomanometry at last? St George and
Sutherland Medical Research Foundation Symposium:
Kogarah, NSW.
Robertson F (2012) Breastfeeding and High Risk
Pregnancy. Annual St George Breastfeeding Conference:
Kogarah, NSW.
Rolley J, Fernandez R, Everett B, Mohan S, Davidson
P (2012) Factors Associated with Dietary Practices and
Heart Disease Prevention Among Indian Australians: A
Focus Group Study. Cardiac Society of Australia and New
Zealand: Brisbane.
Rolley J, Fernandez R, Everett B, Mohan S, Davidson P
(2012) Perception of Medication Taking Among Asian
Indian Australians: A Focus Group Study. Cardiac Society
of Australia and New Zealand: Brisbane.
Tranter S (2013) Management of CKD Innovative
approaches to best practice: chronic disease management
in the Community workshop - GP NSW: Sydney, NSW.
Tranter S, Josland E (2013) Association of nutritional
status and the future choice of dialysis option in patients
attending the multidisciplinary predialysis assessment
clinic. Renal Society of Australasia Conference: Hobart.
Tranter S, Josland E (2013) Nutritional profile of patients at
enrolment to the multidisciplinary predialysis clinic 20022012. Renal Society of Australasia Conference: Hobart.
Turner K, Burns T (2013) The role of a renal transplant
recipient coordinator in a non-transplanting unit.
Transplant Nurses of Australasia Annual Conference
Sydney, NSW.
Manning, V (2012) To NUM or not to NUM – that is the
question? Leadership and Practice Development in
Health: Quality and Safety through Workplace Learning
Conference: Hobart.
Walter L (2013) Impact from point of care devices
on emergency department patient processing times
compared with central laboratory testing of blood
samples: a randomised controlled trial and costeffectiveness analysis. International Conference of
Emergency Nursing: Melbourne.
Romero B (2012) The emergency flow Coordinator
International Conference of Emergency Nursing: Hobart.
Romero B (2012) To identify delay reasons for ED patients
at 4 and 8 hours allowing the early identification and
135
SOUTH EASTERN
SYDNEY
LABORATORY
SERVICES
Anatomical Pathology
>
137
>
Anatomical Pathology (SEALS)
St George Hospital
Head of Department
Dr Con Theocharous MBBS FRCPA, Conjoint Lecturer
UNSW
Senior Medical
Dr Leon Vonthethoff MBBS FRCPA
Dr Veli Marjoniemi MBBS BSc FRCPA, Conjoint Senior
Lecturer UNSW
Dr Kim Tran MBBS FRCPA, Conjoint Lecturer UNSW
Dr Jill Griffith BMed(Hons) FRCPA
Dr Louella Davey MBBS FRCPA
A/Prof Ewan Millar BSc(Hons) MBChB FRCPath FRCPA MD
FFSc(RCPA), Conjoint Assoc Prof UNSW & UWS; Visiting
Pathologist Kinghorn Cancer Centre & Garvan Institute of
Medical Research.
Research Staff
Julia Beretov BSc DipEd (hospital scientist & PhD
candidate)
Wei Melbourne MSc (hospital scientist)
Research Grants
NHMRC Program Grant ID No: 535903
Principal investigators Daly RJ, Horvath LG, Millar EKA,
Ormandy CJ, Kench JG, O’Toole SA.
Project title Molecular markers of phenotype, therapeutic
responsiveness and prognosis in human cancers. Total
awarded: $11,128,320. 2009-2013.
AL.Biomarkers of therapeutic response to tamoxifen in
ER+ breast cancer in the context of IBCSG Trials VIII and
IX. $50,000. 2010-2012.
Illawarra Health and Medical Research Institute small
project grant. V Ramachandran, J McArthur, SandersonSmith, R Sluyter, M Lonergan, EKA Millar.Development of
an inducible animal model for acute post-streptococcal
glomerulonephritis. Total awarded: $10,000. 2012.
Original Peer-Reviewed Publications
2012
Coates AS, Millar EKA, O’Toole S, Musgrove E, Viale G,
Regan M, Goldhirsch A, Gelber RD, Price KN, CastiglioneGertsch M, Sutherland RL. Qualitative prognostic
interaction between immunohistochemical expression of
p53 and estrogen receptor in patients with node-negative
breast cancer. Results from International Breast Cancer
Study Group Trials 8 and 9. Breast Cancer Res. 2012 Nov
5;14(6):R143.
Chow HT, Tran K, Millar EKA, Lynch J, Murrell DM. Diverse
presentations of carcinoma erysipelatoides. Case reports
in dermatological medicine 2012:134938.
Hao J, Madigan MC, Khatri A, Power CA, Hung TT,
Beretov J, Chang L, Xiao W, Cozzi PJ, Graham PH,
Kearsley JH, Li Y. In vitro and in vivo prostate cancer
metastasis and chemoresistance can be modulated by
expression of either CD44 or CD147. PLoS One. 2012;7(8)
Cancer Australia Project Grant 626201
Investigators: Graham PH, Delaney G, Millar EKA, Capp
A. A Randomised comparison of anastrozole commenced
before and continued during adjuvant radiotherapy for
breast cancer versus anastrozole and subsequent antioestrogen therapy delayed until after radiotherapy (STARS
- Study of Anastrozole and Radiotherapy Sequencing),
$660,000. 2010-2012.
Wei Melbourne, Kim Tran , Loreena Johnson , Paul de
Souza , William J. Lynch. hENT1 expression in human
urothelium; Evaluating hENT1 prognostic potential for
intravesical Gemcitabine treatment come in patients with
superficial urothelial carcinoma. BJUI, vol 109, supple 4
April 2012.
Cancer Institute NSW Translational Program Grant 10/
TPG/1-04. Investigators: Horvath L, Kench J, Boyer M,
Millar E, O’Toole S, Beith J and Grimison P. Personalised
medicine for cancer: molecular biomarkers in clinical
decision making for breast, prostate and pancreatic cancer.
$3,714,000. 2010-2014.
O’Toole, Beith J, Millar EKA, West R, McLean A, Cazet A,
Swarbrick A, Oakes S. New therapeutic targets in triple
negative breast cancer. Journal of Clinical Pathology.
2013. 66(6):530-42.
ANZ Breast Cancer Trials Group. Investigators: Sutherland
RL, O’Toole SA, Millar EKA, Musgrove EA, Coates
2013
C Wolford, M Leon, A Merchant, X Yin, S Jalgaonkar, Y
Seok Chang, J Dominick, S McConoughey, E Zmuda,
SA O’Toole, EKA Millar, CL Shapiro, M Ostrowski, RL
Sutherland, T Hai. ATF3 links host adaptive-response
137
to breast cancer metastasis. J Clin Invest. 2013 Jul
1;123(7):2893-906.
Urothelial Carcinoma – A translational study of potential
predictive biomarkers, MSc Thesis (UNSW).
Browne BC, Hochgräfe F, Wu J, Millar EK, Barraclough
J, Stone A, McCloy RA, Lee CS, Roberts C, Ali NA,
Boulghourjian A, Schmich F, Linding R, Farrow L, Gee
JM, Nicholson RI, O’Toole SA, Sutherland RL, Musgrove
EA, Butt AJ, Daly RJ. Global characterization of signalling
networks associated with tamoxifen resistance in breast
cancer. FEBS J. 2013 280(21):5237-57.
Presentations at Scientific Meetings and
Conferences
Tiu A, Reynolds R, Millar EKA, Aslan P. Neuroblastoma
of the adult kidney, the report of a case. Urology. 2013
Jul;82(1):11-3.
Hau E, Browne L, Capp A, Delaney G, Fox C, Kearsley
JH, Millar EKA, Nassar EH, Papadatos G, Graham PH: The
impact of breast cosmetic and functional outcomes on
quality of life: long term results from the St George and
Wollongong Randomized Breast Boost Trial. Breast Cancer
Res Treat. 2013;139(1):115-23.
Schade B, Lesurf R, Sanguin-Gendreau V , Millar EKA,
Zardawi SJ, Lopez-Knowles E, Sutherland RL, O’Toole
SA, Kahn M, Hallett M, Muller WJ. Targeting B-catenin
signaling in ErbB2-driven breast cancer impairs
metastasis and expression of ErbB2. Cancer Res. 2013;
15:73(14):4474-87.
Ni J, Cozzi P, Hao J, Beretov J, Chang L, Duan W, Shigdar
S, Delprado W, Graham P, Bucci J, Kearsley J, Li Y.
Epithelial cell adhesion molecule (EpCAM) is associated
with prostate cancer metastasis and chemo/radioresistance
via the PI3K/Akt/mTOR signaling pathway. Int J Biochem
Cell Biol. 2013 Dec;45(12):2736-48.
Venugopal SS1, Yan W, Frew JW, Cohn HI, Rhodes LM,
Tran K, Melbourne W, Nelson JA, Sturm M, Fogarty J,
Marinkovich MP, Igawa S, Ishida-Yamamoto A, Murrell
DF. A phase II randomized vehicle-controlled trial of
intradermal allogeneic fibroblasts for recessive dystrophic
epidermolysis bullosa. J Am Acad Dermatol. 2013
Dec;69(6):898-908.e7. doi: 10.1016/j.jaad.2013.08.014.
Epub 2013 Sep 24.
Other Published Material
EKA Millar, Studies on biomarker development in breast
cancer. MD Thesis (UNSW).
Wei Melbourne, Immunohistochemistry of Superficial
138
2012 - International
EKA Millar, Intrinsic subtype and its clinical significance
in early node negative breast cancer: results from two
randomized trials of adjuvant chemoendocrine therapy.
American Society of Clinical Oncology (ASCO) Annual
Meeting, Chicago, USA, June.
EKA Millar, Sydney International Breast Cancer Conference
2012: “Basal-like breast cancer”. Sydney, October 24-26.
2012 - National
Wei Melbourne, Kim Tran, Loreena Johnson, Paul de
Souza, William J. Lynch. hENT1 expression in human
urothelium; Evaluating hENT1 prognostic potential for
intravesical Gemcitabine treatment come in patients with
superficial urothelial carcinoma 65Th Annual Scientific
meeting Darwin April.
2013 - International
Wei Melbourne, Kim Tran, Dedee F. Murrell. Collagen
VII monoclonal antibodies in the diagnosis of dystrophic
epidermolysis bullosa by immunofluorescence mapping.
Beijing China BIT’s 5th Annual Internation Congress of
Antibodies (ICA-2013).
Cohn HI; Tran K; Chow CW; Palmer E; Turner A; South
AP; Murrell DF, 2013, ‘A novel mutation in COL7A1,
G2269R causing nail only DDEB and RDEB, with a
presentation similar to TBDN at birth when coinherited
with R2814X COL7A1 mutation’, in Journal of investigative
dermatology, NATURE PUBLISHING GROUP, pp.
S141 - S141, presented at International Investigative
Dermatology Meeting, Edinburgh, Scotland, 8 - 11 May.
Yan WF; Venugopal SS; Frew JW; Rhodes LM; Melbourne
W; Tran K; Murrell DF, 2013, ‘Translocation of the cytokine
HMGB1 coincides with wound healing in fibroblastinjected wounds of recessive dystrophic epidermolysis
bullosa’, in Journal Of Investigative Dermatology,
Nature Publishing Group, pp. S137 - S137, presented
at International Investigative Dermatology Meeting,
Edinburgh, Scotland, 8 - 11 May.
AGED AND
EXTENDED CARE
Aged Care,
St George Hospital
>
140
Rehabilitation Medicine,
>
St George Hospital
141
Southcare,
The Sutherland Hospital >
142
>
Department of Aged Care
St George Hospital
Head of Department
Research Grants
Peter Smerdely MBBS (Hons) MPH PhD FRACP
Senior Staff Specialist Geriatric Medicine & Endocrinology
Director Department of Aged Care, St George Hospital
Co Director, Aged & Extended Care, St George and
Sutherland Hospitals Health Service, Network Executive
Clinical Director, Conjoint Associate Professor UNSW
St George & Sutherland Medical Research Foundation.
The Impact of Routine Post-Discharge Medical Evaluations
of Nursing Home Patients Following Acute Hospital
Admissions. Chief Investigator Dr Nicholas Cordato.
$50,000, 2012.
Senior Medical, Geriatric Medicine
Litsa Morfis, MBBS FRACP
Staff Specialist, Geriatric Medicine
Conjoint Lecturer, UNSW
Chris Dedousis, MBBS FRACP
Senior Staff Specialist, Geriatric Medicine & Thoracic
Medicine
Conjoint Appointment with Southcare, Sutherland
Hospital, Conjoint Senior Lecturer, UNSW
Sarah Baldwin MBBS FRACP
Staff Specialist, Geriatric Medicine, Conjoint Lecturer,
UNSW
Tony Youssef BSc (MED) MBBS FRACP
Staff Specialist, Geriatric Medicine
Conjoint Appointment with Southcare, Sutherland Hospital
Nicholas Cordato, MBBS (Hons 1) FRACP PhD
Senior Staff Specialist, Geriatric Medicine
Conjoint Appointment with CRAGS, Calvary Hospital,
Conjoint Senior Lecturer, UNSW,
Grant Pickard MBChB FRACP
Staff Specialist, Geriatric Medicine
Appointed to Medical Assessment Unit
Yun Xu MBBS FRACP
Staff Specialist, Geriatric Medicine
Appointed to Medical Assessment Unit
Conjoint appointment with CRAGS, Calvary Hospital
Louise Baird MBBS FRACP Conjoint Lecturer, UNSW
Staff Specialist, Geriatric Medicine
Appointed to Medical Assessment Unit & Aged Care
Kannie Chuang MBBS FRACP
Staff Specialist, Geriatric Medicine
Appointed to General Medicine Unit
140
Research Projects in Progress
The Impact of Routine Post-Discharge Medical Evaluations
of Nursing Home Patients Following Acute Hospital
Admissions. Chief Investigator Dr Nicholas Cordato.
The 4AT Study: Screening for Delirium in an Elderly
Hospital Population. Dr Jayita De, Dr Anne Wand,
Professor Peter Smerdely
Presentations at Scientific Meetings and
Conferences
Cordato, N. Invited Platform Presentation. The
Extrapyramidal Spectrum. Australian and New Zealand
Society for Geriatric Medicine ANZSGM Annual Scientific
Meeting 2012, Sydney.
Community Engagement
All staff members are actively involved with the
community. Regular lectures are given to groups auspiced
by Alzheimer’s Australia, Department of health and St
George Hospital.
“Delirium Care: What You Need to Know”, Flip Chart
Staff Educational Resource. Developed collaboratively
with Associate Professor Victoria Traynor, the University of
Wollongong.
Peter Smerdely - Member, SESLHD Board.
Nicholas Cordato - Senior Research Fellow, Neurosciences
Research Australia, Randwick.
>
Department of Rehabilitation Medicine
St George Hospital
Head of Department
Research Projects in Progress
Dr John Estell MBBS, BS, MSpMed, FAFRM(RACP)
Cost Benefit of Rehabilitation Care
John Estell and Kenneth Chan.
Senior Medical
Dr Scott Hannan MBBS, BMedSci, FAFRM(RACP) FACRM
Conjoint Senior Lecturer UNSW
Dr Kenneth Chan MBBS, BSc(Med) FAFRM(RACP)
Dr Brenda Slee MBBS MPH FAFRM(RACP)
A/Professor Andrew Cole MBBS(Hons) FAFRM(RACP)
FACRM Conjoint Associate Professor, School of
Community Medicine UNSW
On-Site versus Off-site Rehabilitation in Stroke
John Estell.
On-Site versus Off-site Rehabilitation in Orthopaedic
Conditions, John Estell.
Interventional Spasticity Management
Scott Hannan, Brenda Slee and John Estell.
Rehabilitation Intensity of Therapy
John Estell.
Acute Rehabilitation Intervention in Trauma (multicentre
study coordinated through St Vincent’s Hospital) John
Estell.
Original Peer-Reviewed Publications
Poulos, CJ., Eagar, K., Faux, SG., Estell, JJ & Crotty, M.
(2013). Subacute care funding in the firing line. Medical
Journal of Australia, 199 (2), 92-93.
Presentations at Scientific Meetings/
Conferences
2013 International
John Estell, Justine Tinker. Best Practice Learning – the
Australian Experience, Regional Spasticity Education
Conference Seoul Korea, June.
John Estell, Spasticity Management and its Impact on
Function. Excellence in Spasticity Management, AsiaPacific Conference. Seoul, South Korea, June.
2013 National
John Estell, Sub Acute Models of Care, Australasian
Faculty of Rehabilitative Medicine Conference, Sydney.
Kenneth Chan, On-site vs Off-site Stroke Rehabilitation
– which is more cost effective, Australasian Faculty of
Rehabilitative Medicine Conference, Sydney.
141
>
Southcare, Sutherland Hospital and
Community Services
Head of Department
A/Prof Peter Gonski MBBS BMedSci FRACP
conjoint A/Prof UNSW
Senior Medical
Nyein Nyein Nyi Nyi MBBS FRACP
Chris Dedousis MBBS FRACP
Stephen Phoon MBBS FRACP
Bethlyn Gill MBBS FRACP
Philip Conroy MBBS FRACP
Lucy Ramon MBBS FAFRM (RACP)
Shikha Jain MBBS FRACP
Tony Youssef BSc(Med) MBBS FRACP
Research Staff
Ms A.Stewart CNC
Research Projects in Progress
VAPOUR study- A Controlled Trial of Vertebroplasty for
Acute Painful Osteoporotic FractURes.
William.Clark, Terry Diamond, Patrick McNeil; Peter
Gonski; Peter Smerdely; Glen Schlaphoff; Derek Glenn;
John Rouse; Paul Bird; Chris Dedousis.
INSPIRED study- Improving Service Provision for Early
Onset Dementia.
Brian Draper; Henry Brodaty; Adrienne Withall; Prasad
Nishtala; John Hodges; Peter Gonski; Clement Loy;
Colleen Mckinnon; Julian Trollor ; Perminder Sachdev ;
Christopher Poulos; Robert Cumming; Bruce Brew.
Rehabilitation Heel Injury Prevention Project
Ann Stewart.
Original Peer-Reviewed Publications
Gonski PN, Moon I. Outcomes of a Behaviour Unit in an
Aged care Service Arch Gerontol Geriatr 2012,55:60-65.
Gonski P, Ye X. Fractures related to falls in older patients
attending an Emergency Department Australasian Journal
on Ageing 2013,32 (1):64-66.
Presentations at Scientific Meetings and
Conferences
2012 National
Gonski PN, Why I prescribe medications for dementia.
ANZSGM Scientific meeting Sydney.
142
ALLIED HEALTH
Nutrition and Dietetics >
144
Occupational Therapy
>
146
Physiotherapy
>
147
Speech Pathology
>
148
143
>
Nutrition and Dietetics,
St George Hospital
Head of Department
Janet Bell (BSc, M NutDiet), Honorary Senior Fellow Illawarra Health and Medical Research Institute, School of
Medicine, University of Wollongong
Dietitians
Maria Chan, PhD, (awaiting to be conferred), BSc(Hons)
MNutDiet GradDipExSpSc AdvAPD, Senior Renal
Dietitian, Conjoint Associate Lecturer - St. George Clinical
School, School of Medicine, University of New South
Wales Honorary Senior Fellow - Illawarra health and
medical Research Institute, School of Medicine, University
of Wollongong
Avesani CM, Trolonge S, Deleaval P, Baria F, Mafra D,
Faxen-Irving G, Chauveau P, Teta D, Kamimura MA,
Cuppari L, Chan M, Heimburger O and Fouque D.
Physical activity and energy expenditure in haemaodialysis
patients: an international survey. Nephrol Dial
Transplantation. 2012 Jun;27(6):2430-4.
Chan M, Nutrition, diabetes and chronic kidney disease,
Australian Diabetes Educator Volume 15 Number 3,
August 2012, 17-23.
2013
Rachel Pons, BNutDietet
Lauren Reece, BNutDietet
Johnson DW, Atai E, Chan M, Phoon RKS, Scott C,
Tussaint N, Turner GI, Usherwood T, and Wiggins, K. KHACARI guideline: Early chronic kidney disease: detection,
prevention and management. Nephrology 18 (2013)
340–350.
Research Projects in Progress
Other Published Material
Does a dietitian-led nutrition care pathway improve
outcomes in patients with liver cirrhosis attending the Liver
Clinic at St George Hospital?
Harris, D, Rangan, G, Kairaitis, L and Elder, G. Pocket
Guide to Basic Clinical Dialysis 2 edition. Authors: Michelle
Ryan, Maria Chan and Murielle Ryan. Chapter 2 Nutrition.
Publisher, McGraw-Hill Australia PTY LTD. 2012.
Principal investigators: Rachel Pons, Lauren Reece, Janet
Bell, Amany Zekry.
Nutritional Factors and Clinical Outcomes of Patients with
End Stage Kidney Disease. Implications for practice from
researching the practice framework.
Principal investigators: Maria Chan, Prof. John Kelly
(UNSW), Prof. Marijka Batterham (UOW), Prof. Linda
Tapsell (UOW).
Original Peer-Reviewed Publications
2012
Chan M, Kelly J, Batterham M and Tapsell L. Malnutrition
(Subjective Global Assessment) Scores and Serum Albumin
Levels, but not Body Mass Index Values, at Initiation of
Dialysis are Independent Predictors of Mortality: A 10-Year
Clinical Cohort Study. J Ren Nutr 2012; 22(6): 547–557.
Manning F, Harris K, Duncan R, Walton K, Bracks J, Larby
L, Vari L, Jukkola K, Bell J, Chan M and Batterham M.
Additional feeding assistance improves the energy and
protein intakes of hospitalised elderly patients. A health
services evaluation. Appetite 2012, 59(2): 471–477.
144
Workforce recommendations for renal dietitians in
Australia and New Zealand, produced by the Australian
and New Zealand renal dietitians workforce planning
group. Dietitian Association of Australia, 2012.
Presentations at Scientific Meetings and
Conferences
2012 – International
Chan M, Kelly J, Batterham M and Tapsell L. Nutritional
characteristics and dietary intake of patients attending
the pre-dialysis assessment clinic. Proceedings of the 16th
International Congress of Nutrition and Metabolism in
Renal Disease (ICNMRD), June, 2012 (Honolulu, Hawaii).
(Poster).
Chan M, Kelly J, Batterham M and Tapsell L. Self-reported
appetite and intake adequacy in patients with non-dialysis
chronic kidney disease. Proceedings of the 16th ICNMRD,
June, 2012 (Honolulu, Hawaii).
2013 - International
Patwardhan A, Ryan C and Chan M, (workshop leader),
Evidence and Practice Guidelines for the Nutritional
Management of Adult Kidney Transplant Recipients. 16th
International Congress of Dietetics (Sydney, Australia).
Chan M, Patwardhan A, Lambert K, and Crosby C
(workshop leader). Evidence and practice guidelines for
the nutritional management of people with chronic kidney
disease stages 1–3, early to moderate renal insufficiency
(GFR 30–90 mL/min/1.73m2). 16th International Congress
of Dietetics (Sydney, Australia).
Janet Bell
Home Enteral Nutrition Co Chair, Agency for Clinical
Information.
2013 National
Chan, M. Invited lecture; Nutritional factors affecting
clinical outcomes of patients with End stage kidney
disease. The Australasian Society for Parenteral and
Enteral Nutrition (AuSPEN), Annual Scientific Meeting,
Sydney, November, 2013.
Chan M, Kelly J, Batterham M and Tapsell L. Nutritional
characteristics and dietary intake of patients at enrolment
to the pre-dialysis assessment clinic. Dietitians Association
of Australia 30th National Conference, May. Canberra,
Australia.
Chan M, Kelly J, Batterham M and Tapsell L. Self-reported
appetite and adequacy of energy and protein intakes in
patients with non-dialysis chronic kidney disease, Dietitians
Association of Australia 30th National Conference, May,
Canberra, Australia.
Chan M, Kelly J, Batterham M and Tapsell L.Nutritional
status is associated with the future treatment choice - renal
replacement therapy vs. conservative care in end stage
kidney disease patients attending the multidisciplinary
pre-dialysis assessment clinic. Australian and New Zealand
Society of Nephrology, Brisbane, Australia.
Community Engagement
Maria Chan
Allied Health Representative, Ministry of Health - Renal
Plan Reference Group for 2013 to 2022
Allied Health Representative, ACI, Renal Service Network
(RSN) Executive Committee, NSW Health
Allied Health Representative, ACI, Renal Service Network
(RSN) Transplant sub-committee, NSW Health.
145
>
Occupational Therapy,
St George Hospital
Head of Department
Sharryn Fitzgerald B.App.Sc (OT)
Research Staff
Ms Pamela Maryse Arndt BAppSc(OT)
Mr Glenn Paull RN BN(Honours) Master of Nursing
Presentations at Scientific Meetings and
Conferences
2013 National
Arndt PM, Paull G.
Living Well with Heart Failure: a role for Occupational
Therapy in the management of chronic heart failure.
Australian Cardiovascular Health & Rehabilitation
Association Annual Scientific Meeting – Melbourne.
Oral presentation selected for the clinical prize session
146
>
Physiotherapy ,
St George Hospital
Head of Department
Jason Phillips, B.App.Sc (Physio)
SGSHHS Sector head Physiotherapy
Susan Sellars, B.App.Sc (Physio)
St George Hospital Physiotherapy Unit Head
Senior Physiotherapists
Wendy Hayes, APA, M. Continence and Women’s Health,
PGCert Pelvic Floor Rehab, Dip Physiotherapy, Women’s
Health Senior Physiotherapist, Conjoint Lecturer UNSW.
Wendy Chaseling, APA M.Hlth.Sc (cardiopul. physio,
USyd), M.Ed (UNSW) , B.App.Sc (physio., USyd) ICU Senior
Physiotherapist, Cardiorespiratory Physiotherapist.
Research Grants
NHMRC TEAM study: Carol Hodgson, Chief Investigator
(The Alfred Hospital, Melbourne), Sue Berney, Rinaldo
Bellomo, Linda Denehy, Megan Harrold, Lisa Higgins, Jeff
Presnell, Dr Manoj Saxena (St George Hospital), Elizabeth
Skinner, Steve Webb, Paul Young, Heidi Buhr Site
Investigator: Wendy Chaseling, Physiotherapist St George
Hospital
Presentations at Scientific Meetings and
Conferences
2012 - International
Hayes, W. A prospective Randomised Controlled
Trial Comparing pelvic Floor Treatments by a Pelvic
Floor Physiotherapist Versus Extracorporeal magnetic
Stimulation. The RCT compared treatments for
women with Stress Urinary Incontinence. International
Urogynaecology Association Conference, Brisbane,
November. (Podium Presentation and Poster).
Community Engagement
Wendy Chaseling
Chair of Working Party for Agency for Clinical Innovation–
Intensive Care Co-Ordination and Monitoring Unit Best
Practice Guideline for Suctioning. Systematic Review
conducted. Clinical Practice Guidelines for all clinical
disciplines (including Medical, Physiotherapy and Nursing)
written and published: http://intensivecare.hsnet.nsw.gov.
au/icwiki/index.php/Suction
TEAM (Trial of Early Activity and Mobility in Intensive Care)
$45,000: 2011-2013
Research Projects in Progress
TEAM study: Observational study to review the current
practice of patient mobility in 25 Intensive Care Units
across Australia and New Zealand, to determine barriers to
mobility and what type of activities are undertaken by ICU
patients.
Principal investigators (as above) Site Investigator: Wendy
Chaseling, Physiotherapist St George Hospital
Other Published Material
Harris, D, Rangan, G, Kairaitis, L and Elder, G. Pocket
Guide to Basic Clinical Dialysis 2 edition. Authors: Michelle
Ryan, Maria Chan and Murielle Ryan. Chapter 2 Nutrition.
Publisher, McGraw-Hill Australia PTY LTD. 2012.
Workforce recommendations for renal dietitians in
Australia and New Zealand, produced by the Australian
and New Zealand renal dietitians workforce planning
group. Dietitian Association of Australia, 2012.
147
>
Speech Pathology
Head of Department
Tracy Kelly, B.App.Sc (Speech Pathology)
Senior Speech Pathologists
Julia Maclean, PhD; M.Sc. (Medicine); B.App.Sc (Speech
Pathology)
Wendy Relf, M.HealthSc. (Communications), B.App.Sc
(Speech Pathology), BA (Linguistics/Psych)
Research Grants
NHMRC Predicting dysphagia-related complications and
improving outcomes in patients treated with head and
neck radiotherapy. Prof Ian Cook, Dr Michal Szczesniak, Dr
Julia Maclean, A/Prof Peter Graham, Dr Taher Omari.
$301,624 (2012-2014).
Research Projects in Progress
Predicting dysphagia-related complications and improving
outcomes in patients treated with head and neck .
radiotherapy. Prof Ian Cook, Dr Michal Szczesniak, Dr Julia
Maclean, A/Prof Peter Graham, Dr Taher Omari. (Women’s
and Children’s Health, Adelaide).
Prospective, randomized controlled trial of cricopharyngeal
dilatation in post-laryngectomy dysphagia. Dr Peter Wu,
Prof Ian Cook, Dr Michal Szczesniak, Dr Julia Maclean.
Influence of Altered Pharyngo-esophageal Biomechanical
Parameters on Swallowing and Speech Function in
Laryngectomees. Ms Teng Zhang Professor Ian Cook, Dr
Michal Szczesniak, A/Prof Paul Bertrand (UNSW), Dr Julia
Maclean.
Original Peer-Reviewed Publications
Krishnan, S. and Maclean J (2013). Practice of
laryngectomy rehabilitation interventions: a perspective
from Australia. Current Opinion in Otolaryngology and
Head and Neck Surgery 21(3):224-229.
Other Published Material
Perry, A. and Maclean, J. (2012) Rehabilitation after
Treatment for Recurrent Head and Neck Cancer.
In H. Mehanna and K. Ang (Eds), Head and Neck
Cancer Recurrence: Evidence-based, Multidisciplinary
Management (pp. 253-259). Germany: Thieme.
148
Maclean, J – Co-Author - ACI - Care of adult patients in
acute care facilities with a tracheostomy – Clinical Practice
Guideline 2013.
Maclean, J – Co-Author - Speech Pathology Australia Clinical Guideline – Laryngectomy Management 2012.
Presentations at Scientific Meetings and
Conferences
2012 - International
Maclean, J.C., Szczesniak M, Zhang, T, Graham, P, Cook IJ.
- Dysphagia Research Society, Toronto, USA, March 2012.
Dysphagia is a prevalent and under-recognized
complication of head and neck radiotherapy.
Maclean J, Szczesniak M, Paramsothy S, Zhang T, Graham,
P, Cook IJ. Australian and New Zealand Head and Neck
Cancer Society, Brisbane, October, 2012, Oesophageal
dysmotility in laryngectomy patients: An unrecognized
association.
2012 - National
Maclean J, Szczesniak M, Paramsothy S, Zhang T, Graham,
P, Cook IJ. Australian and New Zealand Head and Neck
Cancer Society, Brisbane, October, 2012, Oesophageal
dysmotility in laryngectomy patients: An unrecognized
association.
Maclean, J.C., Szczesniak M, Graham, P, Cook IJ.
Australian and New Zealand Head and Neck Cancer
Society, Brisbane, October, 2012, Long-term dysphagia
following Radiotherapy.
Maclean, J.C., Australian and New Zealand Head and
Neck Cancer Society, Brisbane, October, 2012, invited
panellist IFHNOS Session 3: Multidisciplinary Therapy.
2013 - International
Maclean, J.C., Ward EC., Findlay M, Rees G
Dysphagia Research Society, Seattle, USA, March 2013.
Dysphagia and nutritional management in Australian and
New Zealand head and neck cancer centres.
2013 - National
Maclean, J.C., Szczesniak M, Graham, P, Cook IJ.
Australian and New Zealand Head and Neck Cancer
Society, Melbourne, September, 2013, Cricopharyngeal
dysfunction – assessment and treatment.
Community Engagement
Julia Maclean
Executive member – Australian and New Zealand Head
and Neck Cancer Research Foundation
Executive Australian and New Zealand Head and Neck
Cancer Society.
Wendy Relf
Representative - ACI/Stroke Services NSW
149
ERRATUM
In the 2010-11 Research Report, the following report from
Mental Health was inadvertently cut during the printing
process. The full version of the report appears below.
1. Department title – Mental Health Unit, Mental
Health Academic Unit / School of Psychiatry
2. Departmental Staff*
Dr Margot Phillips
BABSc (Med) MBBS FRANZCP
Vocational registrars, advanced trainees
Dr Roslyn Lai (MBBS, MD) - 2011
Senior research staff
Dr Angelo Alonzo (BA, BSc (Hons), Ph.D)
Dr Donel Martin (MClinNeuroPsych; PhD), BA (Hons);
MClinNeuroPsy
Head of Department
Dr Kevin Clarke
MBBS(Hons),
MHA, Grad Dip FBS, FRANZCP
Research assistants
Conjoint Lecturer UNSW
Professor Colleen Loo (MB.BS. (Hons), FRANZCP, MD.;
Professor – School of Psychiatry UNSW;
Michael Player (BPsych (Hons), Ph.D)
Varsha Sivalingham (ILP)
Rose Liu (ILP)
Natalie Johnston (BSc, MB BS)
Research Psychiatrist – Black Dog Institute)
Nursing & Allied Health research staff
Dr Matthew Boulton
BMBS BSc FRANZCP
Psychiatrist – PECC
Conjoint Associate Lecturer UNSW
Dr Grace Chan (BA Nursing), PhD)
Dr Anne Camac
MBBS, FRANZCP
Conjoint Lecturer UNSW
Dr Mesut Cetiner
MBBS Bsc (Med) (Hons) FRANZCP
Certificate POA & Conjoint Lecturer UNSW
Dr Denise Cupina
MD, FRANZCP
Conjoint Senior Lecturer UNSW
Dr Spencer Duke
BMedSci BM BS MRCPsych FRANZCP
Conjoint Senior Lecturer UNSW
Dr Andrew Gerard
MBBS FRANZCP
Dr Peter Jones
MBChB MRCPsych FRANZCP
Dr Andrew Kaill
BMED FRANZCP TA
Dr Yana Kay
MBBS, BA, PHD FRANZCP
Conjoint Lecturer UNSW
Dr Andrew Pethebridge
MBBS, MM (Ven Sci), MM, FRANZCP, FAChAM
Conjoint Senior Lecturer UNSW
Natalie Katalinic (BA (Hons)
Research students
3. Research Grants#
Category I - Nationally Competitive Grants
NHMRC Project Grant ID 510142 - A Sham-controlled
Study of Transcranial Direct Current Stimulation (tDCS) as a
Treatment for Depression.
Professor Colleen Loo
$400,500 (2008-2010)
NHMRC Project Grant ID 568678 - A controlled study of
bilateral electroconvulsive therapy
Professor Colleen Loo, Professor Isaac Schweitzer
$421,268 (2009-2011)
NHMRC Project Grant ID 1004152 – Role of neurogenesis
in clinical recovery from depression during ECT:
Application of a novel in vivo magnetic resonance
spectroscopy technology.
Dr Michael Valenzuela, Professor Colleen Loo, Dr Jesus
Pujol, Professor Petar Djuric, Dr Dennis Velakoulis,
Associate Professor Murat Yucel, Professor Mike Dragunow
$505,312 (2011-2013)
NARSAD young Investigator Award – Remediation of
cognitive dysfunction in euthymic bipolar disorder patients
using transcranial direct current stimulation (tDCS)
Dr Donel Martin
$60,000 USD (2011-2012)
Category II - Other competitive grants
Category III – Industry and other research funding:
UNSW Gold Star Award. Outcomes of Standard and
151
Ultrabrief Pulsewidth ECT.
Professor Colleen Loo
$40000 (2010)
Genetic Factors, Biomarkers and Outcomes of Brain
Stimulation
Professor Colleen Loo
UNSW Gold Star Award. A comparative study of two forms
of ECT: standard and ultrabrief pulsewidth.
Professor Colleen Loo
$40000 (2011)
A study of transcranial electrical stimulation
Professor Colleen Loo, Prof Phil Mitchell, Prof Perminder
Sachdev, Dr Donel Martin, Dr Angelo Alonzo
UNSW Gold Star Award. A controlled trial of ketamine as
an adjunctive agent in ECT.
Professor Colleen Loo
$40000 (2011)
UNSW Early Career Faculty Research Grant – The effect of
timing of transcranial direct current stimulation (tDCS) for
enhancing learning during cognitive training.
Dr Donel Martin
$17,000 (2011)
4. Research Projects in Progress
A controlled study of ultrabrief pulsewidth ECT
Professor Colleen Loo, Professor Isaac Schweitzer
An effectiveness trial assessing the efficacy and cognitive
side effects of BT, BF and RUL ECT
Professor Colleen Loo, Dr Bill Lyndon
A double-blind, randomised, placebo-controlled study of
adjunctive ketamine anaesthesia in ECT (electroconvulsive
therapy)
Professor Colleen Loo, Associate Professor Ross
MacPherson, Dr Ron Woodey, Dr Bill Lyndon
Validation of a new in vivo MRI approach for measurement
of hippocampal neurogenesis in humans
Dr Michael Valenzuela, Professor Colleen Loo
Genetic factors, biomarkers, and outcomes in ECT
Professor Colleen Loo
A sham-controlled study of transcranial direct current
stimulation (tDCS) as a treatment for depression
Professor Colleen Loo, Professor Philip Mitchell, Professor
Perminder Sachdev, Melissa Pigot
Open pilot trial of transcranial direct current stimulation
(tDCS) using alternative electrode montages.
Professor Colleen Loo, Prof Phil Mitchell, Prof Perminder
Sachev, Dr Donel Martin, Dr Angelo Alonzo
Investigating methods to enhance the excitatory effects of
transcranial direct current stimulation (tDCS).
Professor Colleen Loo, Prof Phil Mitchell, Prof Perminder
Sachev, Dr Donel Martin, Dr Angelo Alonzo
Comparison of measures of plasticity
Professor Colleen Loo, A/Prof Janet Taylor, Prof Perminder
Sachev, Michael Player
152
A study of ketamine as an antidepressant
Professor Colleen Loo, Dr John Leyden, Dr Simon Harper,
Dr Jenny McGoldrick, Dr Jarrett Johnston, Dr Harry Wark,
Natalie Katalinic, Dr Grace Chan
Open Pilot Trial of Temporal Lobe Transcranial Direct
Current Stimulation (tDCS) for Depression
Professor Colleen Loo, Dr Angelo Alonzo, Dr Donel Martin
Investigating Direct current Stimulation as a Treatment for
Depression: A Controlled Clinical Trial
Professor Colleen Loo, Professor Philip Mitchell, Professor
Perminder Sachdev, Dr Angelo Alonzo, Dr Donel Martin
Enhancing cognitive training using transcranial direct
current stimulation (tDCS): a randomised controlled trial.
Dr Donel Martin, Professor Colleen Loo, Dr Melissa Green
The Effect of Timing of Transcranial Direct Current
Stimulation (tDCS) for Enhancing Learning During
Cognitive Training
Dr Donel Martin, Professor Colleen Loo, Dr Melissa Green,
Dr Angelo Alonzo
Remediation of Cognitive Dysfunction in Euthymic Bipolar
Disorder Patients Using Transcranial Direct Current
Stimulation (tDCS): A pilot study
Dr Donel Martin, Professor Colleen Loo, Dr Melissa Green,
Professor Philip Mitchell, Dr Angelo Alonzo
Neuroplasticity induced by transcranial direct current
stimulation treatment.
Professor Colleen Loo, Dr Janet Taylor, Michael Player
5. Original Peer-Reviewed Publications
Loo C, Sachdev P, Martin D, Pigot M, Alonzo A, Malhi
G, Lagopoulos J, & Mitchell P. A double-blind, shamcontrolled trial of transcranial direct current stimulation
for the treatment of depression. International Journal of
Neuropsychopharmacology 2010; 13:61-69.
O’Reardon JP, Solvason HB, Janicak PG, Sampson S,
Isenberg KE, Nahas Z, McDonald WM, Avery D, Fitzgerald
PB, Loo C, Demitrack MA, George MS, Sackeim HA. Reply
Regarding “Efficacy and Safety of Transcranial Magnetic
Stimulation in the Acute Treatment of Major Depression:
A Multisite Randomized Controlled Trial”. Biological
Psychiatry 2010; 67:e15-e17.
Arul-Anandam A, Loo CK & Mitchell P. Induction of
hypomanic episode with transcranial direct current
stimulation. Journal of ECT 2010; 26:68-69.
Disorders, 2011; 132: 1-13.
Loo C, Sainsbury K, Mitchell P, Hadzi-Pavlovic D, Sachdev
P. A Sham-Controlled Trial of Left and Right Temporal
rTMS for the Treatment of Auditory Hallucinations.
Psychological Medicine 2010; 40(4):541-546.
Loo C, Martin D, Alonzo A, Gandevia S, Mitchell P,
Sachdev P. Avoiding Skin Burns with Transcranial
Direct Current Stimulation: Preliminary Considerations.
International Journal of Neuropsychopharmacology,
2011;14(3):425-6.
Loo C, Kaill A, Paton P, Simpson B. The Difficult-toTreat Electroconvulsive Therapy Patient - Strategies for
Augmenting Outcomes. Journal of Affective Disorders
2010; 124(3):219-227.
Matheson S, Green M, Loo C & Carr V. Quality assessment
and comparison of evidence for electroconvulsive therapy
and repetitive transcranial magnetic stimulation for
schizophrenia: a systematic meta-review. Schizophrenia
Research 2010; 118(1-3): 201-210).
MacPherson R, Lawford J, Simpson B, Mahon M, Scott D
and Loo CK. Low dose lignocaine added to propofol does
not attenuate the response to electroconvulsive Therapy.
Journal of Affective Disorders, 2010; 126(1-2): 330-3.
Loo CK, Simpson B, MacPherson R. Augmentation
Strategies in Electroconvulsive Therapy. Journal of ECT
2010; 26: 202-207.
Matheson S, Green M, Loo C & Carr V. A change in
the conclusions of a recent systematic meta-review:
repetitive transcranial magnetic stimulation is effective for
the negative symptoms of schizophrenia. Schizophrenia
Research, 2010; 122 (1-3): 276-277.
Haskett R & Loo C. Role of Adjunctive Psychotropic
Medications during ECT in the Treatment of Depression,
Mania and Schizophrenia. J ECT 2010; 26:196-201.
Loo C, Kayess R, Alonzo A, Rendina N, Trollor J. Mental
Health Legislation & Psychiatric Treatments in NSW:
Electroconvulsive Therapy and Deep Brain Stimulation.
Australasian Psychiatry, 2010; 18(5): 417-425.
Janicak, P, Nahas Z, Lisanby S, Solvason HB, Sampson S,
McDonald W, Marangell L, Rosenquist P, McCall V, Kimball
J, O’Reardon J, Loo C, Husain M, Krystal A, Gilmer W,
Dowd S, Demitrack M, Schatzberg A.4Durability of Clinical
Benefit With Transcranial Magnetic Stimulation (TMS) in
the Treatment of Pharmacoresistant Major Depression:
Assessment of Relapse During a Six-Month, Multisite,
Open-Label Study. Brain Stimulation, 2010; 3(4): 187-199.
Ehnvall A, Mitchell P, Hadzi-Pavlovic D, Loo C, Breakspear
M, Wright A, Roberts G, Frankland A, Corry J. Pain
and rejection sensitivity in bipolar depression. Bipolar
Disorders, 2011; 13(1): 59-66.
Loo C, Katalinic N, Mitchell P, Greenberg B. Physical
Treatments for Bipolar Disorder: A Review of
Electroconvulsive therapy, Stereotactic Surgery and
other Brain Stimulation Techniques. Journal of Affective
Loo C, Mahon M, Katalinic N, Lyndon B, Hadzi-Pavlovic
D. Predictors of Response to Ultrabrief Right Unilateral
Electroconvulsive Therapy. Journal of Affective Disorders
2011; 130: 192-197.
Galvez V, Alonzo A, Martin D, Mitchell P, Sachdev P,
Loo C. Hypomania induction in a bipolar II patient with
transcranial Direct Current Stimulation (tDCS). Journal of
ECT 2011; 27(3):256-258.
Stewart P, Loo C, MacPherson R, Hadzi-Pavlovic D.
The Effect of Electrode Placement and Pulse Width on
Asystole and Bradycardia during the Electroconvulsive
Therapy Stimulus. International Journal of
Neuropsychopharmacology 2011; 14(5):585-94.
Rushby J, Vercammen A, Loo C, Short B, Weickert C,
Weickert T. Frontal versus parietal contributions to
probabilistic association learning. Cerebral Cortex 2011;
21(8):1879-1888.
Mitchell P, Frankland A, Hadzi-Pavlovic D, Roberts G,
Corry J, Wright A, Loo C, Breakspear M. A comparison
of depressive episodes in bipolar disorder and major
depressive disorder within bipolar disorder pedigrees.
British J Psychiatry 2011; 199: 303-309. Doi 10.1192/bjp.
bp.110.088823
Alonzo A, Brassil J, Taylor J, Martin D, Loo C. Daily
transcranial Direct Current Stimulation (tDCS) leads to
greater increases in cortical excitability than second
daily tDCS. Brain Stimulation 2011, doi:10.1016/j.
brs.2011.04.006.
Martin D, Alonzo A, Mitchell P, Sachdev P, Galvez V, Loo C.
Fronto-extracephalic transcranial direct current stimulation
as a treatment for major depression: An open-label pilot
study. Journal of Affective Disorders 2011; 134(1-3):459463.
Vercammen A, Rushby J, Loo C, Short B, Weickert C,
Weickert T. Transcranial Direct Current Stimulation (tDCS)
influences probabilistic association learning in people with
schizophrenia. Schizophrenia Research 2011; 131(1-3):198205.
Bai S, Loo C, Dokos S. A computational model of
direct brain excitation induced by electroconvulsive
therapy: comparison among three conventional
electrode placements. Brain Stimulation. doi:10.1016/j.
brs.2011.07.004
153
6. Other published material (Books, book
chapters, reviews,)
ECT”. NSW Health ECT conference, March 25-26, 2010.
Sydney
Walter G, Rey J, Ghaziudding N, Loo C. Electroconvulsive
Therapy, Transcranial Magnetic Stimulation and Vagus
Nerve Stimulation (chapter). In: Martin A, Scahill L,
Kratcochvil C (Editors). Pediatric Psychopharmacology:
Principles and Practice, Second Edition (pp. 363-373). New
York: Oxford University Press, 2010.
Invited Lecture “Principles of Brain Stimulation”. NSW
RANZCP Advanced Trainees Program. Sydney, 24 June,
2010.
Loo C, Greenberg B, Mitchell P. Non-pharmacotherapeutic
Somatic Treatments for Bipolar Disorder (ECT, DBS,
rTMS) (chapter). In: Manji H & Zarate C (eds) Behavioral
Neurobiology of Bipolar Disorder and Its Treatment (pp.
285-302). Springer Verlag, 2011.
Mitchell P, Hadzi-Pavlovic D, Loo C. Course and Outcome
of Bipolar Disorder (chapter). In: Manji H & Zarate C (eds)
Behavioral Neurobiology of Bipolar Disorder and Its
Treatment (pp. 1-18). Springer Verlag, 2011.
7. Presentations at Scientific Meetings/
Conferences
Loo C, Sainsbury K, Mitchell P, Hadzi-Pavlovic D, Sachdev
P. A Sham-controlled Trial of Left and Right Temporal rTMS
for the Treatment of Auditory Hallucinations. Australian
and NZ Journal of Psychiatry, 2010; 44 (1): A15-16.
Weickert T, Rushby J, Vercammen A, Weickert C, Loo
C. Effects of Transcranial Direct Current Stimulation
on Probabilistic Feedback Learning in People with
Schizophrenia. Australian and NZ Journal of Psychiatry,
2010; 44 (1): A16.
Rushby JA, Loo C, Weickert CS, Weickert TW. Effects of
transcranial direct current stimulation on probabilistic
category learning in patients with schizophrenia. Schizophr
Res, 2010, 117 (Nos 2-3):177.
Mitchell, PB, Frankland, A, Hadzi-Pavlovic, D, Roberts,
G, Wright, A, Loo, CK, Malhi & Breakspear, MJ 2010, A
comparison of the phenomenology and illness course of
major depressive episodes in major depressive disorder
and bipolar I and bipolar II disorders, Bipolar Disorders,
2010 Vol. 12 (Suppl. 1) page 38
Mitchell P, Frankland A, Hadzi-Pavlovic D, Roberts G,
Wright A, Loo C, Breakspear M. On the nature of major
depressive disorder (unipolar depression) in bipolar
disorder pedigrees. Int J Neuropsychopharm, 2010; 13:
130-130, Suppl. 1
Weickert T, Gendy R, Chan M, Loo C, Mitchell PB,
Weickert CS. Probabilistic association learning impairment
predicts degree of schizotypal personality traits.
Schizophrenia Bulletin, 2011, 37: 233, Suppl. 1.
Invited speaker, “Electrode placement and dosing in
154
Invited Lecturer, NSW Institute of Psychiatry 3rd Yr
Trainees, ECT and Brain Stimulation. Sydney 22 July, 2010.
Invited main speaker, Ramsay Healthcare Continuing
Education Workshop on “ECT and TMS”, Adelaide Clinic,
SA, 9 Sept, 2010
Keynote Speaker, Queensland Neuropsychiatry Interest
Group 7th Annual ECT Forum, Brisbane. “ECT – Stimulus
Parameters”. Brisbane, 16 Oct, 2010.
Presentation “tDCS in depression” and Panel Discussant
“Physical Treatments of Depression”, Depression
Masterclass, hosted by Servier. Sydney 7 Nov, 2010.
Plenary Speaker “Synergistic antidepressant effects with
ketamine and ECT” Australasian Society for Psychiatric
Research, 6-8 Dec, Sydney, 2010
Chair, Early Career Researchers symposium. Australasian
Society for Psychiatric Research, 6-8 Dec, Sydney, 2010
Invited speaker, UNSW Brain Sciences Symposium ‘Brain
Stimulation”. Topic: Brain stimulation - a tool for treating
psychiatric disorders”, Sydney, 15 March, 2011
Invited Speaker, First National Symposium on Translational
Psychiatry. Topic: “ECT, TMS and DCS: Established and
Emerging Treatments”. Canberra 4-5 April, 2011
Guest Speaker, NSW Health Adult Acute Inpatient
Benchmarking Forum. Topic: “ECT”. Sydney, 3 May, 2011.
Westmead Hospital Psychiatry Grand Rounds. “Recent
Advances in Treatments for Depresssion”. 7 July, 2011
Psychiatry Grand Rounds, St George Hospital. New
Treatments in Depression – Ketamine. 4 August, 2011.
Psychiatry Grand Rounds, The Sutherland Hospital. New
Treatments in depression. 25 August, 2011.
Invited symposium speaker, Australian Society of
Anaesthetists National Scientific Congress, Sydney, 8 Sept
2011. Strategies for Optimising ECT.
St John of God Burwood Grand Rounds. Electroconvulsive
Therapy. 2 Sept, 2011
Australiasian Society for Bipolar Disorders Conference.
ECT workshop chair & speaker: “Optimising ECT: The
importance of stimulus parameters” . Sydney Oct 20-22,
2011
Australiasian Society for Bipolar Disorders Conference.
Brain stimulation symposium chair and speaker “Novel
Brain stimulation – what is the therapeutic potential?”
Sydney Oct 20-22, 2011
Queensland Mental Health symposium: An Update on
ECT. Invited speaker “New Brain Stimulation Treatment
and ECT”. Brisbane Oct 29, 2011
NSW Mental Health Advocacy Service Training Day.
“Electroconvulsive Therapy and NSW Health Guidelines”.
15 November, 2011. Sydney.
International
Bai S, Loo C, Dokos S. A Computational Model of Direct
Brain Stimulation by Electroconvulsive Therapy. Conf Proc
IEEE Eng Med Biol Soc. 2010; 1:2069-72.
Invited workshop presentation/ Meeting Faculty,
International Society for ECT and Neurostimulation. Topic:
“Transcranial Direct Current Stimulation for Depression”.
Hawaii, 15 May, 2011.
8. Community Engagement
“Old Wives Tale: Electroshock treatment is harmful”.
Women’s Day, 5 April, 2010
Southern Courier – article on tDCS. June 2010.
ECT research quoted in UK paper, Daily Mail, “How short
shocks could transform depression.: June 15, 2010.
“NSW Restrictions on ECT and DBS “not justifiable”
Psychiatry Update Newsletter, 30 Sept, 2010. [Australasian
Psychiatry 2010; 18: 417-425 quoted]
“Rise and Shine” – interview on ECT. Channel Nine, 2 May,
2010.
Channel 10 News – interview on tDCS, 9 June, 2010.
Interview for radio 2SER on use of ECT, 25.5.2010.
Interview for ABC Radio National, PM program, 8 June,
2010, on tDCS.
Interview for ABC Radio National, Mornings with Deborah
Cameron, on tDCS trial in depression. 6 April, 2011
Interview for ABC Radio Canberra, on tDCS trial in
depression. 6 April, 2011
Interview for ABC Radio Central West, on tDCS trial in
depression. 6 April, 2011
Medical Observer – interview re ECT 8.2.2011
Sun Herald, interviewed for article on ECT, 26 June, 2011
155
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