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Download Extensions of Mendelian Inheritance
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Extensions of Mendelian Inheritance • Incomplete dominance • Co-Dominance • Multiple alleles • Sex Linkage • Sex Influenced • Sex Limited Incomplete dominance • Heterozygous has intermediate phenotype between 2 extremes • Show 1:2:1 ratio of genotype and phenotype • Familial Hypercholesterolemia • Elevated blood serum cholesterol levels Incomplete dominance • Tay Sachs and Sickle Cell Anemia • Heterozygous are intermediate at the biochemical level. Multiple Alleles &Co-Dominance Multiple Alleles Penetrance & Expressivity • Penetrance= Proportion with genotype who express the phenotype • Expressivity= how the genotype is expressed in the phenotype Sex Linked inheritance • Sex-linkage • Sex limited and Sex influenced traits X linked traits Sex-Linkage • Carried on x chromosome • Males hemizygous • Show mendelian ratio of 3:1 • Males show recessive trait • Females are normal diploid, rarer in females X-Linked dominant X-linked recessive • Primarily in males • Grandfather to grandson • Rare in females Primarily in males • Grandfather to grandson • Rare in females Color Blindness Muscular dystrophy Hemophilia Sex limited • Autosomal trait • Expressed only in one sex • Milk production Sex influenced traits • Autosomal trait • Hormonal balance • Dominant in one sex, recessive in the other • Pattern baldness
