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Chapter 5 The Integumentary System CHAPTER CONTENTS Introduction The Practice and the Practitioners The Skin The Epidermis The Dermis Subcutaneous Tissue Keratin and Melanin Glands within the Skin The Structure of Hair and Nails Common Integumentary System Disorders and Procedures Common Abbreviations Exercises Pre-Quiz Checklist Chapter Quiz 36 36 CHAPTER 5 THE INTEGUMENTARY SYSTEM 37 ntegumentum is Latin for “covering” or “shelter,” and thus the skin, nails, and hair covering our bodies is called, collectively, the integumentary system. There are only two layers of skin, the epidermis and the dermis. The epidermis is divisible into five sublayers and the dermis into two sublayers, the names of which will be given later. Table 5-1 lists word elements that are used in forming terms related to the integumentary system. I TABLE 5-1 WORD ELEMENTS RELATED TO THE INTEGUMENTARY SYSTEM Word or Element corium (KO-ree-uhm) cutis cyan/o -cyte dermatomegaly (DURmah-toh-MEG-ah-lee) dermatoplasty (dur-MAToh-plass-tee) derm/o; dermat/o epifollicul/o kerat/o leuk/o melan/o onych/o onychotomy (on-ih-KOT-oh-mee) paronychia (pahr-oh-NIK-ee-ah) -phyte pil/o subsudor/i xer/o Type Latin word for “skin” Latin word meaning “skin”; sometimes used to form a medical phrase, such as cutis anserina, the technical name for “goose flesh”; cutis is also the origin of the adjective cutaneous, which refers to the skin. root suffix derm/a/t/o (skin); -megaly (enlarged) derm/a/t/o (skin); -plasty (surgical repair) root prefix root root root root root onych/o (nail); -tomy (incision) para- (adjacent); onych/o (nail); -ia (condition) suffix root prefix root root Refers to synonym for dermis skin blue cell disorder in which the skin hangs in folds plastic surgery of the skin skin upon horn-like white black nail incision into a nail condition resulting in inflammation around the nail plant hair below sweat dry THE PRACTICE AND THE PRACTITIONERS As shown in the preceding table, dermat/o means “skin,” and as you have already learned, -logy means “study of.” Coupling the root dermat/o with the suffix -logy gives us the term dermatology, which names the specialty dealing with the skin. Dropping the -y and adding -ist gives us dermatologist, the word for a physician who specializes in dermatology and who diagnoses and treats skin abnormalities. 38 PART 1 THE SKIN The skin is said to be the body’s largest organ, and since the skin covers the entire body—more than 20 square feet on average—and weighs about 24 pounds, the claim would seem to be true. As already noted earlier, the skin is composed of two parts: the epidermis is the outer layer, and the dermis is the inner layer. The Epidermis The epidermis protects the body from the outside world, a pretty big job for something only three one-thousandths of an inch thick. The epidermis on the palms of our hands and the soles of our feet is somewhat thicker than that, but even there, it is only about two one-hundredths of an inch thick. The epidermis is divisible into five sublayers, which are listed with brief descriptions in Table 5-2. TABLE 5-2 SUBLAYERS OF THE EPIDERMIS Epidermal Skin Layer stratum corneum stratum lucidum stratum granulosum stratum spinosum stratum germinativum Brief Description the tough, waterproof outer sublayer of the skin the transparent, barely discernible sublayer just below the stratum corneum the grainy sublayer between the stratum lucidum and stratum spinosum the spiny sublayer just below the stratum ganulosum; contains cells that create an immune response to protect the body against foreign bodies that get through the first three outer sublayers of skin the innermost sublayer of skin, which butts against the loose connective tissue of the dermis; forms epidermal ridges that connect with the dermis and also gives the stratum corneum its distinctive pattern, as in a fingerprint The epidermis is also sometimes referred to as epithelial tissue because it is e avascular, which means “without blood vessels.” However, epithelial tissue is found elsewhere in the body, and for that reason, you should remember that the phrase epithelial tissue is NOT synonymous with the term epidermis. The Dermis The dermis, which may also be called the corium, has two sublayers: the papillary sublayer and the reticular sublayer, the latter being the deeper of the two. Unlike the epidermis, the dermis contains blood vessels and nerves. So if you get a scratch that hurts and/or bleeds, you will know that the scratch extends through CHAPTER 5 Hair THE INTEGUMENTARY SYSTEM 39 Stratum corneum Stratum lucidum Epidermis Stratum granulosum Stratum spinosum Stratum germinativum Dermis Nerve ending Epidermis lifted to reveal papillae of the dermis Epidermis Dermis Blood vessels Sebaceous gland Papillary layer of dermis Nerve endings Reticular layer of dermis Subcutaneous tissue Sweat glands FIGURE 5-1 A cross-sectional view of the skin. Adapted from: Stedman, TE, ed. Stedman’s Medical Dictionary. 27th ed. Baltimore: Lippincott Williams & Wilkins; 2000. the epidermis and into the dermis. The dermis also contains both sebaceous (oilproducing) glands and sudoriferous (sweat-producing) glands. the difference between corium, a synonym for the dermis, and corneum, as e Note in “stratum corneum,” the outermost layer of the epidermis. Subcutaneous Tissue A layer of subcutaneous tissue, located just beneath the dermis, is composed of connective tissue. Synonyms for subcutaneous tissue include hypodermis, subfascia, and the fat layer because subcutaneous tissue stores lipids. The Latin word cutis, which means “skin,” gives us the English adjectives cutaneous and subcutaneous. Although the subcutaneous tissue is, categorically speaking, separate from the skin, its proximity and physiology dictate that it be considered in discussions of the skin and its abnormalities (Figure 5-1). Keratin and Melanin Composed of keratinocytes, keratin is a protein that toughens the outer layer of skin and is a key component in the formation of hair and nails. Melanin, a pigment composed of melanocytes present in the dermis, gives the skin its color and provides protection against the sun’s ultraviolet (UV) rays. Hair and nails are both composed of epithelial cells filled with keratin. Keratinocytes and melanocytes are simply the cells that make up keratin and melanin (recall that the suffix -cyte means “cell”). 40 PART 1 Integumentary System Glands Sebaceous Glands Suderiferous Glands Produce Sebum Produce Sweat Lubricates Hair and skin Cools Skin FIGURE 5-2 Glands, secretions, and functions of the integumentary system. careful to distinguish keratinocytes, which are cells that form keratin, from e Be keratocytes, which are cells in the cornea of the eye. GLANDS WITHIN THE SKIN The sebaceous and sudoriferous glands provide the skin, hair, and nails with the secretions needed to keep the integumentary system in good health (Figure 5-2). THE STRUCTURE OF HAIR AND NAILS A hair follicle is a mass of cells that forms a cavity, out of which a hair grows. The word follicle is derived from a Latin word meaning “small sac.” Most sebaceous glands are located close to, but are not part of, hair follicles. Although they are distinct from hair follicles, sebaceous glands share hair follicle ductwork to transmit their oily secretions to each hair and its adjacent skin. Certain hairless areas of skin, mostly on the face, chest, or back, contain sebaceous glands that have their own follicles and ductwork. Nails are composed of layers of hardened cells of the stratum corneum (the outermost sublayer of the epidermis). CHAPTER 5 THE INTEGUMENTARY SYSTEM 41 DECIPHERING MEDICAL DOCUMENTS Read the following excerpt from a hospital discharge statement and answer the questions: On day two under spinal anesthesia, the left hip was pinned percutaneously with three cannulated screws. Postoperatively she did well and was quite stable. Hematocrit was 32.0, hemoglobin 10.9. 1. Identify and analyze the word that means “through the skin.” 2. To what time period does “postoperatively” refer? 3. What kind of tests are hematocrit and hemoglobin? A. biopsies B. common blood tests C. urinalysis COMMON INTEGUMENTARY SYSTEM DISORDERS AND PROCEDURES Table 5-3 lists common integumentary system disorders and some of the procedures used in their diagnosis and treatment. TABLE 5-3 COMMON DISORDERS AND PROCEDURES ASSOCIATED WITH THE INTEGUMENTARY SYSTEM Term dermatitis dermatoma dermatomegaly dermatomycosis dermatopathy dermatoplasty epidermatitis melanoma onychectomy onychomalacia onychomycosis onychopathy onychoplasty onychotomy paronychia Definition inflammation of the skin skin tumor excessive skin, often hanging in folds fungal infection of the skin any disease of the skin plastic surgery performed on the skin inflammation of the epidermis tumor of the melanocytes surgical removal of a nail softening of the nails fungal infection of a nail any disease of the nails surgical repair of a nail incision into a nail infection around a nail 42 PART 1 A STUDY TABLE 5-1 THE INTEGUMENTARY SYSTEM Term and Pronunciation Analysis Meaning STRUCTURE & FUNCTION avascular (ah-VASS-cue-luhr) corium (KO-ree-uhm) cutaneous (cue-TAYN-ee-uhs) dermis (DUR-muss) epidermal (epp-ih-DUR-muhl) epidermis (epp-ih-DUR-muss) follicle (FAWL-ik-uhl) keratin (KERR-uh-tin) keratinocyte (keh-RAT-ih-no-site) melanin (MELL-uh-nihn) melanocyte (MEL-uh-no-site) sebaceous (she-BAY-shus) stratum corneum (STRAT-uhm COR-nee-uhm) sudoriferous (soo-doe-RIFF-uh-russ) a- (“without”); vascular (adjectival form of the nouns vessel or vein) from the Latin (“skin”) from the Latin word cutis (“skin”) from the Greek word derma (“skin”) epi- (“upon”); dermis (“skin”); -al (adjectival suffix) epi- (“upon”); dermis (“skin”) from the Latin word folliculus (“a small sac”) from the Greek word kera (“horn”) from the Greek word kera (“horn”); -cyte (cell) from the Greek word melas (“black”) from the Greek word melas (“black”); -cyte (cell) from the Latin word sebum (“tallow” and by extension, grease, oil, fat) Latin phrase meaning “tough layer of skin” from two Latin words: sudor (“sweat”) and fero (“to carry”) absence of vessels or veins synonym for dermis adjective referring to the skin inner layer of skin adjectival form of epidermis outer layer of the skin small sac in the skin from which a hair grows protein that forms hair, nails, and the tough outer layer of skin cell that produces keratin dark pigment present in skin and other parts of the body cell that produces melanin adjective describing an oil-producing gland outermost sublayer of the epidermis adjective describing sweat-producing glands COMMON DISORDERS dermatitis (dur-muh-TY-tiss) dermatoma (dur-muh-TOH-muh) dermatomegaly (DUR-mah-toh-MEG-ah-lee) dermatomycosis (DUR-matt-oh-MI-ko-sis) dermatopathy (DUR-mah-TOP-ah-thee) epidermitis (epp-ih-dur-MY-tiss) melanoma (mel-uh-NO-muh) onychomalacia (ON-ih-ko-muh-LAY-shee-uh) derm/a/t/o (“skin”); -itis (“inflammation”) dermat/o (“skin”); -oma (“tumor”) dermat/o (“skin”); -megaly (“enlarged”) dermat/o (“skin”); myc/o (“fungus”); -osis (“abnormal condition”) derm/a/t/o (“skin”); -pathy (“disease”) epi- (“upon”); -dermis (“skin”); -itis (“inflammation”) melan/o (“black”); -oma (“tumor”) onych/o (“nail”); -malacia (“softening”) inflammation of the skin tumor of the skin excessive skin, often hanging in folds fungal infection of the skin any disease of the skin inflammation of the epidermis tumor of the melanocytes softening of the nails CHAPTER 5 A STUDY TABLE 5-1 THE INTEGUMENTARY SYSTEM THE INTEGUMENTARY SYSTEM (co nt inued) Term and Pronunciation Analysis Meaning COMMON DISORDERS onychomycosis (ON-ih-ko-my-KO-sis) onychopathy (on-ih-KOP-uh-thee) paronychia (pahr-oh-NIK-ee-ah) onych/o (“nail”); mycosis (“fungal infection”) onych/o (“nail”); -pathy (“disease”) fungal infection of a nail any disease of the nails para- (“adjacent”); onych/o (“nail”); -ia (“condition”) infection around a nail dermat/o (“skin”); -logist (“practitioner”) dermat/o (“skin”); -logy (“study”) a specialist who diagnoses and treats skin diseases study of the integumentary system derm/a/t/o (“skin”); -plasty (“surgical repair”) onych/o (“nail”); -ectomy (“incision”) plastic surgery performed on the skin surgical removal of a nail onych/o (“nail”); plasty (“repair”) surgical repair of a nail onych/o (“nail”); -tomy (“incision”) incision into a nail cuticle (CUE-tih-kuhl) from the Latin word cutis (“skin”) cyanosis (SY-uh-no-siss) cyan- (“blue”); -osis (“abnormal condition”) epi- (“upon”); dermis (“skin”); -oid (“resemblance”) epi- (“upon”); onych/o (“nail”) the common word used as a synonym for the eponychium abnormal condition signaled by bluish discoloration of tissue resembling the epidermis PRACTICE & PRACTITIONERS dermatologist (dur-muh-TAHL-uh-jist) dermatology (dur–muh-TAHL-uh-jee) SURGICAL PROCEDURES dermatoplasty (dur-MAT-oh-plass-tee) onychectomy (ON-ihk-EHK-toh-mee) onychoplasty (on-ihk-oh-PLASS-tee) onychotomy (on-ih-KOT-oh-mee) ENHANCEMENT TERMS epidermoid (epp-ih-DURM-oyd) eponychium (ep-oh-NIK-ee-uhm) follicular (fah-LIK-u-luhr) lunula (LOON-yu-luh) from the Latin word folliculus (“a small sac”) from the Latin word luna (“moon”) onychia (oh-NIK-ih-ya) onychoid (ON-ik-oyd) onych/o (“nail”); -ia (“condition”) onych/o (“nail”); -oid (“resemblance”) piloid (PY-loyd) pilosebaceous (PY-lo-she-BAY-shus) vellus (VELL-uhs) pil (“hair”); -oid (“resemblance”) pil/o (“hair”); sebaceous (“oil-producing”) from the Latin (“fleece”) thin, transparent layer of skin located at the nail root adjective form of the noun follicle white, crescent-shaped area of a nail infection of a nail bed adjective meaning nail-like in structure or form hair-like adjective referring to the hair and sebaceous glands fine hair that covers much of the body 43 44 PART 1 ABBREVIATION TABLE 5-1 COMMON ABBREVIATIONS: The Integumentary System Abbreviation BSA derm SPF UV Meaning body surface area (used in describing skin damage assessment caused by burns) dermis sun protection factor ultraviolet c Exercises Exercise 5-1 Choosing the Correct Term Fill in the blanks. The outer and inner layers of the skin are called, respectively, the 1)__________________________ and the 2)_________________. The dermis is sometimes called the 3)_____________________________ and contains 4)_________________, or oil-producing glands, along with 5)___________________________, or sweat-producing glands. Hair and nails are both composed of 6)_________________________________________ cells filled with 7)________________________________________, but nails are made even tougher by hardened cells of the 8)______________________, which is the outermost sublayer of the epidermis. Exercises Exercise 5-2 Converting Nouns to Adjectives Convert each of the following nouns to its adjective form using one of the following suffixes: -al, -aneous, -eous, -otic, -ular, -oid, -ous. Noun Adjective Form 1. vessel ____________ 2. epidermis ____________ 3. sebum ____________ 4. cutis ____________ 5. cyanosis ____________ 6. follicle ____________ 7. keratin ____________ CHAPTER 5 THE INTEGUMENTARY SYSTEM 45 Exercises Exercise 5-3 Matching Terms with Definitions Match the numbers in Column 1 with the letters in Column 2 according to the corresponding terms and definitions they designate. Term 1. _____ melanin Definition A. oil-producing glands 2. _____ epidermis B. protein that toughens the outer layer of the skin 3. _____ lunula C. physician who specializes in dermatology and diag- 4. _____ sebaceous D. responsible for pigment or color of skin 5. _____ dermatologist E. the outer layer of the skin 6. _____ stratum corneum F. the white, crescent-shaped area of the nail noses and treats skin abnormalities 7. _____ avascular G. BSA 8. _____ keratin H. without vessels or veins 9. _____ sudoriferous glands 10. _____ body surface area I. the outermost sublayer of the epidermis J. sweat-producing glands Exercises Exercise 5-4 Identifying Skin Layers Label the following skin layers on Figure 5-3. ? • epidermis • dermis • nerve endings • stratum germinativum • subcutaneous tissue 46 PART 1 2 1 5 3 4 FIGURE 5-3 A cross-sectional view of the skin (Exercise 5-4). Exercises Exercise 5-5 True, False, and Correction Read each statement, then indicate whether you think it is true or false. If false, fill in the correct answer in the “Correction, if False” box at the right. True False Correction, if False 1. Eponychium is a thick white layer of skin located around the knuckles. Statement ___ ___ ____________ 2. Stratum corneum is the inner lens aperture of the eye. ___ ___ ____________ 3. Piloid is a capsule-shaped cell found in the epidermis. ___ ___ ____________ 4. Dermatitis is an inflammation of the skin. ___ ___ ____________ 5. Dermis refers to the life cycle of the cuticle. ___ ___ ____________ 6. Sebaceous describes an area consisting of several follicles. ___ ___ ____________ CHAPTER 5 THE INTEGUMENTARY SYSTEM 7. A sudoriferous gland produces sweat. ___ ___ ____________ 8. Avascular is a crowded mass of veins. ___ ___ ____________ 9. Dermatoma is a fungus infection of the skin. ___ ___ ____________ 10. Onychoplasty is the study of skin. ___ ___ ____________ 11. Onychectomy is the surgical removal of a nail. ___ ___ ____________ 12. Onychomalacia is hardening of the skin. ___ ___ ____________ 47 Exercises Exercise 5-6 Complete the Sentences Fill in the missing terms to complete the sentences. 1. Hairs grow from small sacs in the epidermis called _____________. 2. A tumor of the melanocytes is referred to as _____________. 3. The white crescent-shaped moon-like area of the fingernail is called the _____________. 4. The protein _____________ forms hair, nails, and the tough outer layer of skin. 5. The outer layer of skin is the _____________. 6. The adjective _____________ signifies an absence of veins. 7. _____________ is an adjective suffix pertaining to the epidermis. 8. Dermatomycosis is a fungal infection of the _____________. 9. Any disease of the nails may be referred to as an _____________. 10. The study of the integumentary system is called _____________. 11. _____________ is the dark pigment found in skin and other body parts. 12. Epidermitis is an inflammation of the _____________. Pre-Quiz Checklist _____ Study the word elements specific to the integumentary system. _____ Review the definitions and etymologies listed in the study table. _____ Check the exercises with the answers in the Appendix; consult the study table again to correct any errors. 48 PART 1 Chapter Quiz Write the answers to the following questions, using the spaces provided to the right of each question. 1. What are the two major parts of the skin called? 1. _____________________________ 2. What is the function of the epidermis? 2. _____________________________ 3. Which part of the skin do you know you have 3. _____________________________ _____________________________ _____________________________ injured if you have a scratch that hurts and/or bleeds? 4. What is the layer of tissue just beneath the dermis, and what is it composed of? 5. What protein is the key component in the formation of hair and nails? 6. What term names the types of cells that make up the nails? _____________________________ 4. _____________________________ _____________________________ 5. _____________________________ _____________________________ 6. _____________________________ _____________________________ 7. What is the purpose of melanin? 7. _____________________________ 8. How many sublayers do the epidermis and dermis have? 8. _____________________________ 9. What do sudoriferous glands secrete? 9. _____________________________ _____________________________ _____________________________ _____________________________ 10. What is a lunula? 10. _____________________________ _____________________________