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1 Introduction to Body Organization/Metrics RATIONALE The purpose of this Biomedical Sciences Core class introductory module is to acquaint the student with basic terminology, relationships of human anatomy, and metric system units of measurement. It is a foundation module because all of these terms, relationships, and units will be fundamental for understanding the content of the remainder of the course. Additional study of this module material by the Health Sciences student will be beneficial during this course and throughout a health career. Objective 1 Define anatomy, and its subdivisions, and contrast it with physiology. Reading Assignment: Read Text, Pages 4-6. Anatomy is the Study of Structure Subdivisions of anatomy are shown below: Surface Anatomy: Surface of the body. Gross Anatomy: Anatomical structures that observable without the use of a microscope. Systemic Anatomy: Specific systems (e.g., digestive, urinary, skeletal, etc.). Regional Anatomy: Specific regions (e.g., head & neck, trunk, upper and lower limbs, etc.). Developmental Anatomy: Human development from egg to adult. Pathological Anatomy: Structure during disease. Radiographic Anatomy: Structural studies using x-rays. Embryology: Fertilized egg through 8 weeks of development. Histology: Study of tissue structure and function. Cytology: Study of cells. Physiology is the Study of Function 1.1 INTRODUCTION TO BODY ORGANIZATION/METRICS Objective 2 Identify the relationship between structure and function in living things. Reading Assignment: Read Text, Pages 4-6. Anatomy and physiology are inter-related: they depend on each other. Structure determines function. Objective 3 Define cell, tissue, organ, system, and organism. Reading Assignment: Read Text, Page 5-8. Figure 1.1, Page 7. Cell: A collection of molecular structures (molecules). Cells are the basic units of structure and function in living systems. They are the smallest living units in the human body Tissue: A collection of cells and cellular secretions that perform a specific function(s). Organ: A collection of tissues that perform a specific function(s). System: A collection of organs that perform a specific function(s). Organism: A collection of systems---a living thing. Objective 4 Arrange, in order, the six levels of structural organization. Reading Assignment: Read Text, Pages 6-8; Refer to Figure 1.1. 1. Chemical level 2. Cellular level 3. Tissue level 4. Organ level 5. System level 6. Organism level INTRODUCTION TO BODY ORGANIZATION/METRICS 1.2 Objective 5 Identify the functions of the eleven organ systems of the body. Reading Assignment: Refer to Figure 1.2. Integumentary (skin): Protection, regulates body temperature. Skeletal (bones): Support and protection. Muscular (muscles): Movement, maintains posture, and produces heat. Nervous (nerves): Regulates body activities through nerve impulses. Endocrine (glands): Regulates body activities through hormones. Cardiovascular: Transports oxygen and nutrients to cells. Lymphatics: Immunity, fights germs and infections (bacteria, viruses). Respiratory (lungs): Supplies oxygen and eliminates carbon dioxide. Digestive: Performs physical and chemical breakdown of food for use by cells. Urinary: Regulates chemical compostion of blood by eliminating wastes. Reproductive: Reproduces the organism. Objective 6 Describe the human anatomical position. Reading Assignment: Read Text, Pages 15-16; Refer to Figure 1.6 a & b. Anatomical Position: Standing erect, facing observer, feet slightly apart, arms at side, palms forward. 1.3 INTRODUCTION TO BODY ORGANIZATION/METRICS Objective 7 Identify the following anatomical terms and body regions. Reading Assignment: Refer to Figure 1.6 a & b. Body Regions: Cephalic, trunk, cervical, upper and lower limbs. Anatomical Terms: Cranial: Skull Femoral: Thigh Orbital: Eye Carpal: Wrist Buccal: Cheek Metacarpal: Hand Cervical: Neck Patellar: Front of knee Thoracic: Chest Gluteal: Buttock Axillary: Arm pit Plantar: Sole of foot Ante Cubital: Front of elbow Tarsal: Ankle Inguinal: Groin Phalangeal: Fingers Digital: Toes Popliteal: Back of knee Calcaneal: Heal of foot Metarsal: Toes Objective 8 Define the directional terms used in human anatomy. Reading Assignment: Refer to Figure 1.9. Read Text, Page 18. Refer to Figure 1.8 and Table 1.3. Superior: Toward head, top, or above. Inferior: Away from head, bottom, or below. Anterior (Ventral): Toward the front. Posterior (Dorsal): Toward the back. Medial: Toward the midline. Intermediate: Between two structures. Lateral: Away from the midline. Ipsilateral: Same side of midline. Contralateral: Opposite side of midline. Proximal: Closer to point of attachment/trunk. Distal: Farther away from point of attachment/trunk. INTRODUCTION TO BODY ORGANIZATION/METRICS 1.4 Superficial: Close to or on the surface. Deep: Farther away and beneath the surface--more internal. Parietal: Wall of cavity. Visceral: Internal organs enclosed in a cavity, for example, abdominal. Objective 9 Identify the planes commonly used to divide the body into portions. Reading Assignment: Read Text, Page 18-19; Refer to Figure 1.9 and Table 1.4. Coronal (frontal): Divides body into anterior and posterior portions. Sagittal: Divides body into right and left sides. Midsagittal: The specific sagittal plane that is on the midline. Parasagittal: Any sagittal plane that is not on the midline. Horizontal: Divides body into superior and inferior portions. Objective 10 Locate the body cavities listed below: Reading Assignment: Read Text, Pages 19-22; Refer to Figures 1.10 a, b, & c. DORSAL: Posterior region of the body. Cranial: Formed by the skull. Vertebral: Formed by the vertebrae VENTRAL: Anterior portion of the body Thoracic: The chest cavity Mediastinal: Contains everything except the lungs. Pericardial: Contains the heart. Pleural: Contains the lungs. Abdominopelvic: Inferior portion of the ventral cavity. Abdominal: Superior portion of the abdominopelvic cavity. Pelvic: Inferior portion of the abdominal cavity. 1.5 INTRODUCTION TO BODY ORGANIZATION/METRICS Objective 11 Locate the following structures. Reading Assignment: Refer to Figure 2 a-i, Pages 142-149. Anatomical Structures: Superior vena cava (Figure 21.29) Omentum (greater) (Figure 24.2d) Liver (Figure 24.1) Stomach (Figure 21.25) Lungs (Figure 23.1) Small intestine (Figure 24.1) Diaphragm (Figure 23.1) Heart (Figure 20.3) Thyroid gland (Figure 18.1) Esophagus (Figure 24.1) Aorta (Figure 20.3) Kidneys (Figure 26.1) Ureters (Figure 26.1) Urinary bladder (Figure 26.1) Inferior vena cava (Figure 21.29) Trachea (Figure 23.1) Large intestine (Figure 24.23) Carotid arteries (Figure 21.24) Objective 12 Identify the most specific body cavity in which the following organs are located: Reading Assignment: Read Text, Page 19-22. Refer to Figure 1.10. Heart: Pericardial Lungs: Pleural Bronchi: Primarily pleural Stomach: Abdominal Intestines: Abdominopelvic Brain: Cranial Spinal Cord: Vertebral Urinary Bladder: Pelvic Kidneys: Abdominal Sex Organs: Pelvic INTRODUCTION TO BODY ORGANIZATION/METRICS 1.6 Objective 13 Distinguish the nine abdominopelvic regions from the four abdominopelvic quandrants. Reading Assignment: Read Text, Pages 17; Refer to Figure 1.7. Abdominopelvic Quadrants Right Upper Quadrant Left Upper Quadrant (RUQ) (LUQ) Right Lower Quadrant Left Lower Quadrant (RLQ) (LLQ) Abdominopelvic Regions Right Hypochondriac Epigastric Left Hypochondriac Right Lumbar Umbilical Left Lumbar Right Iliac (Inguinal) Hypogastric (pubic) Left Iliac (Inguinal) Objective 14 Identify the abdominopelvic quandrant in which each of the following organs is located: Reading Assignment: Page 17. Refer to Figure 1.7 c. Liver: RUQ (primarily) Spleen: LUQ Left Kidney: LUQ Cecum: RLQ Appendix: RLQ Left Ovary: LLQ 1.7 INTRODUCTION TO BODY ORGANIZATION/METRICS Objective 15 Locate the following bones. Reading Assignment: Refer to Figure 7.6 , and 8.1. Skull: Head Sternum: Breast bone Clavicle: Collar bone Ulna: Medial aspect lower arm Pelvic girdle: Hips Radius: Lateral aspect lower arm Humerus: Upper arm Femur: Thigh bone Vertebral Column: Backbone Patella: Knee cap Tibia: Medial aspect of lower leg (larger bone). Fibula: Lateral aspect of lower leg (smaller bone). Objective 16 Define homeostasis, stress, and identify the relationship between them. Reading Assignment: Read Text, Pages 11. Homeostasis: Appropriate dynamic condition of the internal environment. Stress: Disruption in homeostasis. Examples of Stressors: Occupational duties and responsibilities, air travel, infection, hyperventilation, surgery, heat, cold, hunger, toxins, and disease. Objective 17 Define negative and positive feedback. Describe the negative feedback systems that are responsible for maintaining nervous system homeostasis of blood pressure and endocrine system homeostasis of blood sugar levels. Reading Assignment: Read Text, Pages 12-15; Refer to Figures 1.3, 1.4, 1.5. Table 1.1. Refer to Page 1.9 of these study notes. Positive Feedback Systems: Output products or signals stimulate more output. That is to say, the outputs reinforce or enhance more of the same outputs from the same sources. Positive feedback systems are seldom used in the human body. An everyday example of positive feedback is lighting a fire; the heat from a lit match causes material to combust. This initial flame creates more heat, which then causes additional material to burn, generating more heat, and igniting yet more comustible material. It is a self-perpetuating and enhancing process INTRODUCTION TO BODY ORGANIZATION/METRICS 1.8 Physiological examples of positive feedback include blood clotting and oxytocin’s stimulation of uterine contractions. Negative Feedback Systems: Output products or signals have a negative or limiting effect on further output. In general, a negative feedback system will reduce or cease the action of the output. “Negative” in this case, does not mean “bad”, rather it means to reduce or limit. Negative feedback systems are very common in physiological processes. Negative Feedback Examples: 1.0 Household example: Thermostat control of a furnace. Final Outcome Increased Temperature (toward normal) Input Dropping Temperature Negative Feedback: Deactivation of Thermostat Heat Thermostat. Initial Output = Activate Furnace. Furnace 2.0 Physiological example: Nervous Control of Blood Pressure Final Outcome Increased BP (toward normal) Input Falling BP Negative Feedback: Reduced Signals Beats Faster and Stronger Receptors in Brain. Initial Output = Stimulate Heart Heart 3.0 Physiological example: Endocrine Control of Blood Sugar Final Outcome Reduced Blood Sugar (toward normal) Input Excess Blood Sugar Negative Feedback: Reduced Signals. Receptors in Pancreas. Initial Output = Stimulate Beta Cells Insulin Glandular 1.9 INTRODUCTION TO BODY ORGANIZATION/METRICS Objective 18 Apply knowledge of the metric system to solve problems such as those found in the following Basic Metrics Self Test supplement for Study Notes, Module 1. Reading Assignment: Refer to Pages 1.13-1.27 of these study notes. Pay special attention to conversion factors on 1.22. Additional references in the text Appendix II, A-36 (Table 1) and A-37 (Table 2) Basic Metrics Self Test PART I: Pages: 1.12 to 1.15 PART II: Pages: 1.15 to 1.16 PART III: Pages: 1.17 to 1.21 Part IV: Pages: 1.21 to 1.24 Part V: Pages: 1.24 to1.25 Unit of Measurement Metric System Practice Questions Exponents Conversions Between Metric and English (U.S. Customary Units) Metrics Review Basic Metrics and Conversions kilometer meter decimeter centimeter millimeter micrometer nanometer angstrom km m dm cm mm µm (mcm) nm Å 1 in. (inch) 1 kg (kilogram) 1 L. (liter) = = = 1000 m 1m 1/10 m 1/100 m 1/1000 m 1/1,000,000 m 1/1,000,000,000 m 1/10,000,000,000 m 2.54 cm 2.205 lb. 1.057 qt. 103 m 100 m 10-1 m 10-2 m 10-3 m 10-6 m 10-9 m 10-10 m 1000 1.0 0.1 0.01 0.001 0.000001 0.000000001 0.0000000001 1 qt. (quart) 1 lb. (pound) 1 ml water = = = INTRODUCTION TO BODY ORGANIZATION/METRICS 946 ml 453.6 g 1g 1.10 DIRECTIONAL TERMS SELF TEST Circle the right answer. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 1.11 ANSWERS: Cover until you are finished. The rib cage is superior/inferior to the pelvis. superior The pelvis is superior/inferior to the rib cage. inferior In humans anterior is most similar to ventral/dorsal. ventral The radius is lateral/medial to the ulna. lateral The ulna is lateral/medial to the radius. medial The hand is proximal/distal to the forearm. distal The humerus is proximal/distal to the ulna and radius. proximal The heel is posterior/anterior to the toes. posterior The tibia is lateral/medial to the fibula. medial The diaphragm is superior/inferior to the liver. superior The vena cava and heart are medial/lateral to the lungs. medial The kidneys are lateral /medial to the inferior vena cava. lateral The kidneys are anterior/posterior to other abdominal organs. posterior The trachea is anterior/posterior to the esophagus. anterior The gallbladder is posterior /anterior to the liver. posterior The skin is superficial/deep to the muscles and the bones. superficial The thumb is lateral/medial to the little finger. lateral The ankle is distal/proximal to the foot. proximal The patella is on the anterior/posterior side of the leg. anterior The wrist is distal/proximal to the hand. proximal The foot is distal/proximal to the leg. distal The intestines are inferior/superior to the liver & the diphragm. inferior The nose is on the anterior/posterior side of the head. anterior The ankle is near the distal/proximal part of the lower extremity distal INTRODUCTION TO BODY ORGANIZATION/METRICS BASIC METRICS SELF TEST PART I 1. 2. 3. 4. 5. 6. Units of Measurement ANSWERS: Cover until you are finished. In our English System of measurement, length is measured in yards, feet, and inches. In the Metric System, the basic unit of length is a meter. In the Metric System, you would measure the length of the room in ____________. A meter is a measure of ________________. meters length Americans measure weight in pounds. In the Metric System, weight is measured in grams. In the Metric System, you wouldn’t buy a pound of coffee, you would buy a certain number of ___________ of coffee. A _________ is a unit of weight. grams gram Volume in the English System is expressed in terms of quarts or gallons. In the Metric System, the term liter is used. A liter is a measure of _______________________. In the Metric System, milk comes in_________________, not quarts. volume liters Sometimes it is more convenient to use a term which means many grams, many liters, or many meters. Kilo is a prefix which means 1,000. Kilometer means 1,000 meters. Kilogram means 1,000 grams. 5 kilograms means 5,000 grams. 8 kilograms means_____________ grams. 9,000 meters means ______________________ kilometers. 25,000 grams means 25 _________________. Kilo means _______________________. 8,000 nine kilograms 1,000 Just as it is convenient to use terms which mean larger amounts, it is also convenient to break units of weight, length, or volume into smaller amounts. Deci is a prefix which means one-tenth (1/10). A decimeter means onetenth of a meter. A decigram means _______________________ of a gram. 2 decigrams means _______________________ of a gram. Nine decimeters means _______________________ of a meter. one-tenth two-tenths nine-tenths Since one decigram equals one-tenth of a gram, there are obviously 10 decigrams in a gram. How many deciliters in a liter?_______________________. How many decimeters in 2 meters?_______________________. How many decigrams in 1/2 of a gram?___________. Each decigram equals_________________of a gram. Ten Twenty Five one tenth INTRODUCTION TO BODY ORGANIZATION/METRICS 1.12 7. 8. 9. 10. 11. A prefix for an even smaller measure is called centi. Centi means one-hundredth (1/100). A centiliter equals onehundredth of a liter. A centimeter equals one-hundredth of a meter. Centi means _______________________. A centigram means _______________________ of a gram. A centiliter equals _______________________ of a liter. A centigram equals _______________________ of a gram. The prefix for one-hundredth is ______________. one-hundredth one-hundredth one-hundredth one-hundredth centi Since one centimeter equals one-hundredth (1/100) of a meter, there are 100 centimeters in a meter. How many centiliters in a liter? ______________. How many centigrams in a gram? ______________. How many centigrams in 6 grams? ______________. How many centimeters is 1/2 of a meter ______________. 100 100 600 50 If there are 10 decimeters in a meter, and 100 centimeters in a meter, can you figure out how many centimeters are in each decimeter? ______________. Ten decimeters, each with 10 centimeters, equals one meter and _______ centimeters. Five decimeters equals how many centimeters? ______________. One decimeter equals how many centimeters? ______________. An even smaller measure is denoted by the prefix milli. Milli means one-thousandth (1/1000). A milligram is one-thousandth of a gram. A milliliter is one-thousandth of a liter. A milliliter is _______________________ of a liter. Two milliliters are equal to _____________________ of a liter. 500 milligrams are equal to ________________ of _______________________. Since each milliliter equals one-thousandth of a liter, there are a thousand milliliters in a liter. There are a thousand ____________________ in one gram. There are 2000 milligrams in _____________ grams. There are _____________________ millimeters in one-half of a meter. 25,000 millimeters are equal to _______________ meters. Nine grams are equal to ____________________ milligrams. There are still some smaller divisions which will be presented later. Before proceeding, please be aware that most of the terms we have used are usually abbreviated. 1.13 INTRODUCTION TO BODY ORGANIZATION/METRICS 10 100 50 10 one-thousandth two-thousandths 500-thousandths a gram milligrams two 500 25 9,000 l2. l3. 14. The abbreviation for gram is a small “g”. Five grams written as 5 ______________. The abbreviation for meter is a small “m” and liter is a capital “L” or small “l”. Write the abbreviations for eight liters: ______________. One hundred meters is abbreviated as ______________. When using the abbreviation for the prefix kilo, a small “k” is used with the abbreviation for the unit of measure it is modifying. For example, “k” is used with a lower case “g” for gram, “m” for meter, and “l” for liter. For example: 57 kilometers is written 57 km. Five kilograms is written as: ____________. Write 62 kiloliters: _______________. In practice kl is almost never used. Instead, 1000 liters is defined as one cubic meter (m3). Liter is more typically abbreviated using the small “l” as in: decilter (dl), centiliter (cl), or milliliter (ml). Similar measures of weight and length include: centigram (cg), milligram (mg), centimeter (cm), and milligram (mg). Write five milligrams. _______________________. Write 10 deciliters. _______________________. Write 8 millimeters. _______________________. Write 50 centimeters. _______________________. g 8L 100 m 5 kg; 62 kl 5 mg 10 dl 8 mm 50 cm As we mentioned previously, there are even smaller divisions than one-thousandth. These smaller divisions are rarely, if ever, written as fractions. They are usually written as decimals. These divisions are commonly used in science, industry, and health professions. You need to be quite familiar with these divisions and their abbreviations because you will encounter these terms throughout your studies of the Health Sciences. 15. 16. Micro is a prefix that means the decimal has six places after it. For example, one micrometer is written 0.000001 meter. One microliter is written as ____________liter. One microgram is written as _______________gram. Four micrograms is equal to _______________ gram. 0.000012 m is equal to ______________ micrometers. Twenty-eight micrograms is equal to: _____________ g. 0.000001 0.000001 0.000004 12 0.000028 Nano is a prefix that means the decimal has nine places after it. A nanogram is: 0.000000001 gram. A nanometer is written 0.000000001m A nanoliter is written _______________________ L. 5 nanoliters is written _______________________ L. 15 nanograms is written _______________________ g. 38 nanometers is written _______________________ m. 0.000000001 0.000000005 0.000000015 0.000000038 INTRODUCTION TO BODY ORGANIZATION/METRICS 1.14 17. Angstrom is a term that is normally only used to measure length (in meters only), such as the wavelength of light. Angstrom means that there are ten places after the decimal: 0.0000000001 m represents one angstrom. Write the decimal form for 5 angstroms: ________________m. Write the term for 13 angstroms. _________________ m. 0.0000000005 0.0000000013 Just as kilo, deci, centi and milli had abbreviations, so do the prefixes micro, nano and angstrom. 18. 19. 20. Obviously you can’t use a small “m” for micro because it would be confused with milli. The abbreviation for micro is the Greek symbol for the letter “mu” which is written µ. Sometimes “mc “ is used instead of µ . 0.000001 meter is written in abbreviated form as 1 µm (mcm). 0.000001 liter is written in abbreviated form as 1 µl (mcl). 0.000001 gram is written in abbreviated form as: 1 ____________. Write the abbreviation for 0.000008 g. ______________. Write the abbreviation for 0.000010 l. ______________. Write the abbreviation for 0.000058 m. ______________. 3 µg is written as: ______________ g. 12 µl is written _____________ l. µg 8 µg 10 µl 58 µm 0.000003 0.000012 A small “n” is used to abbreviate the prefix nano. 1 nanogram is written 1 ng. 0.000000005 m is written 5 nm. Write the abbreviation for 0.000000007 l. ________. 0.000000027 g is written: _____________. Four nanometers is written as: _____________ m. 25 nanograms is written as _____________ g. 7 nl 27 ng 0.000000004 0.000000025 Angstroms are usually designated by putting a small circle above the letter ‘A’. 25 Å means 25 angstroms or 0.0000000025 m. Remember that angstroms normally only measure length. 6 Å means: _______________ m. 125 Å means: _________________ m. 0.0000000006 0.0000000125 PART II 1.15 Metric Sytem Practice Questions INTRODUCTION TO BODY ORGANIZATION/METRICS 1. The unit of measure of length in the metric system is a _______________________. meter The unit of measure of volume in the metric system is a _______________________ liter The unit of measure of weight in the metric system is a _______________________ gram 4. Kilo means _______________________ 1,000 5. Milli means _______________________ 1/1000 6. Centi means _______________________ 1/100 7. Deci means _______________________ 1/10 8. 58 km means how many meters? ___________________ 58,000 9. 84 meters means how many cm? ____________________ 8,400 10. How many mg in a g? ______________________ 1,000 11. How many ml in a dl? ____________________ 100 12. How many dm in a m? ______________________ 10 13. How many mm in a cm? ______________________ 10 14. How many cl in a l? ______________________ 100 15. 5 g equal ______________________ mg. 5,000 16. 5 g equal _______________________ cg. 500 17. 5 g equal _______________________ dg. 50 18. 1/2 l equals _______________________ dl. 5 19. 1/2 l equals _______________________ cl. 50 20. 1/2 l equals _______________________ ml. 500 21. Write 2 decigrams as a decimal number. _____________ 0.2 g 22. Write 8 nanograms as a decimal number. ____________ 0.000000008 g 23. 0.006 m is equal to _____________________ millimeters. 6 24. Write 12 centimeters as a decimal number. ___________ 0.12 m 25. 0.5 g is equal to 5 _______________________. decigrams 26. 0.0000000002m is equal to 2 _______________________ angstroms 27. 0.05 meter is equal to _______________ centimeters. 5 28. Write 9 milliliters as a decimal number _______________. .009L 29. 28 Å means 28 _______________________. angstroms 2. 3. INTRODUCTION TO BODY ORGANIZATION/METRICS 1.16 30. The abbreviation for microliter is ___________________. µ 1 (mcl) 31. 58ng means 58 _______________________. nanograms 32. 9 µl written as a decimal is _______________________. .000009L Part III 1. 2. 1.17 Exponents Writing all those zeros is very cumbersome. In practice only deci, centi, and milli are typically written as decimals. The smaller numbers are written as exponents. For example, the number 22 means 2 x 2. 23 means 2 x 2 x 2 and so on. The superscript number is called an exponent and it tells you how many times you multiply the base number by itself. Since the Metric System is based on units of 10, we use exponents to the base of 10. 1 x 102 means 1 x 10 x 10 = 100. 2 x 102 means 2 x 10 x 10 = 200. 5 x 102 means 5 x ______ x ______ = ______. 1 x 103 means 1 x _______________________ and equals _______________________. 2 x 103 means 2 x _______________________. and equals ___________________. 10, 10, 500 10 x 10 x 10 1000 10 x 10 x 10 2000 For a number such as 1 x 109 it would be very inconvenient to write as: 1 x 10 x 10 x 10 x 10 x 10 x 10 x 10 x 10 x 10. Instead, we simply move the decimal to the right. For example, 1 x 102 means that first you write the number 1, being sure to put the decimal after it such as 1.0. Next move the decimal to the right of the number (1 in this case) according to the number of places shown by the exponent. Zeros are added as “place holders” as the decimal is moved to the right. Therefore, 1 x 102 is the equivalent of : 1 x 10 x 10 or 100. Try rewriting 2 x 103 as a whole number. First you write the 2 being sure to put the __________ after it. Next move the decimal three places to the _____________ and you have the number_________________. Does 2 x 10 x 10 x 10 equal your answer? _________________. decimal right 2000 Yes. INTRODUCTION TO BODY ORGANIZATION/METRICS 3. Remember, if the exponent is positive, that is if it doesn’t have a minus sign, always move the decimal to the right. If the exponent is negative, always move it to the left. For example, 1 x 10- 2 equals 0.01. Again, write down the whole number 1 making sure you include the decimal point (1.0). Next, move the decimal two places to the left, using zeros as “place holders”, and the correct decimal notation is: 0.01. If the exponent is positive, you move the decimal to the _____________. If the exponent is negative, move the decimal to the ____________. You move the decimal to the right if the exponent is _____________. You move the decimal to the left if the exponent is _____________. Write 3 x 102 as a whole number.______________. Write 1 x 10-6 as a decimal _____________. Did you have trouble with the negative exponent? Write the number 1 putting its decimal after it (1.0). Since the exponent is -6 , you know you move the decimal to the left six places. Count the places. Practice now going both ways. Write 1 x 103 as a number _____________. Write 0.01 as an exponent _____________. Write 5 x 10- 2 as a decimal _____________. Write 200 as an exponent _____________. Write 0.000003 as an exponent _____________. Write 5 x 10- 9 as a decimal _____________. 4. right left positive negative 300 0.000001 1,000 1 x 10-2 0.05 2 x 102 3 x 10-6 0.000000005 From the previous descriptions, there are three ways to write metric terms: A prefix—such as centi, a decimal— .01, or an exponent—1 x 10-2. They all are equivalent. Also, note that anything with the exponent of zero equal one (100 = 1.0; 2.0 x 100 = 2.0) . Fill in the blanks in the chart below: Kilo 1000 ––– Centi Milli Nano 10 10-1 10- 3 10- 9 1 0.1 0.000001 Angstrom Deci, Micro, 103, 10- 2 ,10- 6,10- 10 0.01, 0.001, 0.000000001, 0.0000000001 INTRODUCTION TO BODY ORGANIZATION/METRICS 1.18 5. In Part I of this section you were asked how many millimeters were in a centimeter and other similar questions. There is a quick and simple way to convert between metric units using the exponents. Before proceeding, you need to familiarize yourself with the relative size of the metric units (e.g., which units are larger or smaller than the others). Angstroms are the smallest units we have discussed. Angstroms are smaller than nanometers. Decimeters are larger than millimeters. Millimeters are _____________ than centimeters. Micrometers are _____________ than nanometers. Nanometers are _____________ than angstroms but _____________ than millimeters. Kilometers are _____________than meters. 6. 7. 1.19 There is more than one angstrom in a nanometer, but less than one, or a fraction of a nanometer, in an angstrom. There is more than one millimeter in a centimeter, but _____________ than one centimeter in a millimeter. There is _____________ than one micrometer in a meter. There is _____________ than one nanometer in a millimeter. There is _____________ than one decimeter in a centimeter. There is _____________ than one centimeter in a nanometer. The next procedure in converting units is to examine the exponents. If you need to solve the question: “How many angstroms are in one nanometer?”, the fist step is to subtract the smaller exponent from the larger exponent (ignoring the negative sign). One angstrom is 1 x 10-10 and one nanometer is 1 x 10-9. Subtract the smaller exponent from the larger, (10 minus 9 = 1). This means you are going to move the decimal one place. It is not immediately necessary to know which way to move the decimal: this concern will be addressed once you have practiced subtracting exponents. If you are asked how many angstroms are in a millimeter, you will subtract ________ from ________ which equals ________. INTRODUCTION TO BODY ORGANIZATION/METRICS smaller larger larger smaller larger less more more less less 3,10, 7 8. If you need to determine how many millimeters are in an angstrom, the process is still the same: subtract the smaller exponent 3 from the larger exponent ________ which then equals: ________. The exponent form for a micrometer is _____________. The exponent form for a centimeter is _____________. The first step in converting from one to the other is to _____________ 2 from __________ resulting in the number ________. The exponent form of 1 liter is 1 x 100, The exponent form of 1 deciliter is 1 x 10-1. In order to convert from one to the other, first subtract _____________ from 1 and the answer is _____________. The exponent form for 1 nanoliter is _____________. The exponent form for 1 milliliter is _____________. To convert from one to the other, the first step is to subtract _____________ from _____________ leaving the number _____________. Now that you know how many places to move the decimal it is necessary to determine the direction to move it. Consider the following problem: how many microliters are in a milliliter? Step 1. Write the exponent form for microliter: ___________. Next, write the exponent form for milliliter: ___________. Step 2. Subtract the smaller exponent from the larger which leaves you with the number ____________. This number tells you how many places to move the decimal. Step 3. Determine whether the outcome will be greater than one (whole number), less than one (fraction), or equal to one. If it is greater than one, you move the decimal to the right. If it is less than one, you move the decimal to the left. If it is equal to one, there is no change in the decimal. Since microliters are ____________ than milliliters, there will be ___________ than one microliter in a milliliter. Because there is more than one microliter in a milliliter the decimal is moved to the right. How many places?_____________ (Look at step 2.) Thus, there are 1,000 microliters in one milliliter. 10 7 1 x 10-6 1 x 10-2 subtract 6, 4 0 (zero) 1 1 x 10- 9 1 x 10- 3 3, 9 6 9. 1 x 10- 6 1 x 10- 3 3 smaller more 3 INTRODUCTION TO BODY ORGANIZATION/METRICS 1.20 10. If the reverse question were asked: “how many milliliters is in a microliter?”, the steps from above are used in the same manner, except since milliliters are ____________ than microliters, the decimal is moved to the left (see step 3). There are ____________ nanometers in a decimeter. There are ____________ centiliters in a milliliter. There are ____________ meters in a centimeter. There are ____________ nanometers in a micrometer. There are ____________ angstroms in a micrometer. There are ____________ micrometers in an angstrom. larger 100,000,000 0.1 0.01 1,000 10,000 0.0001 11. Write 5 x 10 x 10 x 10 as an exponent. _____________ 5 x 103 12. Write 0.002 m as an exponent. _____________ 2 x 10- 3 m 13. Write 5 km as an exponent. _____________ 5 x 103 km 14. Write 1 nanometer as decimal. _____________. Write 1 nanometer as an exponent _____________ 0.000000001 m 1 x 10- 9 nm 15. The prefix for 0.01 is _____________. centi 16. Write 5 deciliters as an exponent. _____________ 5 x 10-1 l 17. How many angstroms in one nanometer? ____________ 10 18. How many milligrams in one microgram? _____________ 0.001 19. How many meters in one decimeter? _____________ 0.1 20. How many micrograms in one centigram? ____________ 10,000 PART IV 1. 1.21 Conversions Between Metric and English Units In nearly all fields of science, the Metric System is used because it provides a uniform difference between units; namely 10, or multiples of 10. This is logical and simplifies calculations. However, it is sometimes necessary to convert between metric units and familiar English units such as inches, feet, pounds, and quarts. In microbiology, the system most commonly used is the _____________. Occasionally, we need to convert from the Metric System to the_____________. INTRODUCTION TO BODY ORGANIZATION/METRICS Metric System English System 2. The first step in converting between systems is to select a conversion factor. Conversion factors are usually printed in handy places such as on the back of metric rulers, on wall charts, or in tables at the back of science books. The following conversion factors are used extensively in medicine and will be included in the Biomedical Core exams: 1 in. (inch) 1 oz. (ounce) 1 lb. (pound) 1 qt. (quart) 1 fluid oz. 1 m. (meter) 1 kg. (kilogram) 1 l. (liter) = = = = = = = = 2.54 cm. (centimeters) 28.35 g (grams) 453.6 g (grams) 946 ml (milliliters) 30 ml (milliliters) 39.37 in (inches) 2.205 lb (pounds) 1.057 qt (quarts) If you bought a one lb. bag of potatoes and weighed it on a laboratory balance (Metric System), the lab balance would show: _____________. 3. Conversion factors can also be written as fractions. For example, 4 glasses = 1 quart can be written:4 glasses1 quart. In words, this reads: There are four glasses per 1 quart. The same conversion factor can also be written: 1 quart . In words, this reads: One quart per four 4 glasses glasses. Rewrite the following conversion factors as two fractions: 1 in. = 2.54 cm. 1 lb. = 453.6 g. 1 fluid oz. = 30 ml. 1 kg. = 2.205 lb. 453.6 g / / 4. Many conversions, like those in frames 2 and 3, can be made using very simple mathematics or by reading the appropriate conversion factor. Other conversions need to be done mathematically by a process called dimensional analysis. If your table of conversion factors does not include the exact information you need, you may have to apply a mathematical procedure called ________________ _________________ . / / / / / / / / 1 in. or 2.54 cm1 in. 2.54 cm 1 lb. or 453.6 g lb. 453.6 g 1 fl.oz. or 30 mL1 fl. oz. 30 mL 1 Kg or 2.205 lb.1 kg. 2.205 lb. dimensional analysis INTRODUCTION TO BODY ORGANIZATION/METRICS 1.22 5. 6. 7. In the measurement 1.3 quarts, the word “quart” indicates the dimension. In the measurement 82 ml, the abbreviation “ml” indicates the dimension. In other words, to use dimensional analysis, you analyze the dimension or unit in the measurement. What are the dimensions of the following measurements? 14 g. ______,18 lb.______, 24 in. ______, 65 kg ______. In order to convert between metric and English units, we need to apply a conversion factor in a process called dimensional analysis. Dimensional analysis involves arranging the dimensions (units) so that all cancel except the unit we want to conserve. In dimensional analysis, all the dimensions (units) cancel except ________________ _________________. the unit we are converting into If you have eight glasses of water and want to know how many quart jars you can fill––that is, to convert from glasses to quarts––don’t worry about whether to divide or multiply, just use dimensional analysis. First, write down the number and dimension you want to convert from (8 glasses). Then arrange the conversion factor so that when you multiply, the dimension “glasses” cancels out, and you are left with the desired units–– in this case quarts. 8 glasses x 1 quart = Which units? _____________. 4 glass The reason that the units of glasses “cancels” out is because one of them is above the division line and the other is below. Whenever that happens, the units nullify or cancel each other. Now, do the arithematic: 8 glasses x 1 quart = _____________. 4 glass In using dimensional analysis for the problem above, we first wrote down the number and dimension we wanted to convert from, in this case: _______________. The second thing we wrote down is ____________________________. The conversion factor allows us to _________________ the units that we do not desire in the outcome. 1.23 grams, pounds, inches, kilograms INTRODUCTION TO BODY ORGANIZATION/METRICS quarts 2 quarts 8 glasses the conversion factor cancel 8. Below are examples of dimensional analysis: To convert 5 cm to inches: 5 cm x 1 in = 1.97 in. 2.54 cm To convert 12 inches to cm, you use the same conversion factor, but re-arrange it so that the inches cancel: 12 in x 2.54 cm. = 30.48 cm 1 in. To convert 1.5 m to inches: 1.5 m x 39.37 in. = 59.05 in. 1m Show how you would set up the following problems for dimensional analysis. Convert 10 g to oz: _______________________. 10 oz. x 28.35 g 1 oz 1 fl oz 10 g x 8.35 g Convert 15 ml to fluid oz.: _________________. 15 ml. x 1 fl. oz 30 mL Convert 160 lbs. to kg: ____________________. 160 lb. x 1 kg 2.205 lb. Convert 10 oz. to g: ______________________. INTRODUCTION TO BODY ORGANIZATION/METRICS 1.24 9. In some instances, you might not have a conversion factor that will enable you to cancel out the units. Don’t worry. Use two or more conversion factors in exactly the same way that you used one conversion factor. If you don’t have a conversion factor that will result in the appropriate unit’s cancelling out, you may need to use two or more _____________________. Below are some examples of dimensional analysis problems that use multiple conversion factors. conversion factors Convert 153 inches to mm. 153 in. x 2.54 cm x 10 mm 1 in. 1 cm Convert 10 oz. to kg. 10 oz. x 28.35 g x 1 kg 1 oz 1000 g Notice that it was necessary to use additional conversion factors that were not listed in the table in frame 2. These additional conversion factors were described in Part 1 of this study guide, although they were not specifically referred to as conversion factors. 10. 1.25 There may be several ways to set up dimensional analysis for the same problem. In some cases, the number of conversion factors used may vary depending on the way the problem is set up. In any case, don’t worry; just rearrange the conversion factors so that all the units cancel except those you want to convert to. Show how you would set up the following problems for dimensional analysis. 1m 1 km x 39.37 in. 1000m Convert 12 in. to km. 12 in. x Convert 3000 ml. to quarts 1 fl.oz. 1qt. 3000 mL x x 30 mL 32.oz or 1l 1.057qt. 3000 ml x x 1,000 ml 1l INTRODUCTION TO BODY ORGANIZATION/METRICS Part V 1. 2. Metrics Review The metric system has the great advantage that _______________________________________________ _______________________________________________ ________. its units differ by multiples of 10, simplifying calculations In order to convert between metric and english units, your first step is to select the appropriate _____________ _____________________. conversion factor 3. 1 kg 1l 2.205, 30 1.057, 39.37 4. Rewrite each of the four expressions above as fractions in = _________ lb. = _________ qt. 1 fluid oz. = _________ ml. 1m = _________ in. 1kg I / / or 2.205 lb.1 kg 2.205 lb. 1 fl.oz. or 30 mL1 fl oz. 30 ml 1L or 1.057 qt.1 L 1.057 qt. 1m or 39.37 in.1 m 39.37 in. / / 5. 6. 7. / In dimensional analysis, all the units cancel except the unit that you are ________________. converting into What are the dimensions (units) of the following measurements? 18 cm 37 g. 4 ml. 5,000 m centimeters grams milliliters meters What units remain (do not cancel) in the following problems? 10 m x 39.37 in. 32 cm x 1 in. 1m 2.54 cm 15 cups x 1 quart 4 cups 2 fl.oz. x 30 ml. 1 fluid oz. 17 in. x 1 m 39.37 in. / / inches, inches quarts, meters milliliters INTRODUCTION TO BODY ORGANIZATION/METRICS 1.26 8. 9. 10. 1.27 An average size man (160 lbs.) would weigh approximately how many kg? a. 23 b. 30 c. 45 d. 57 e. 73 A cup of water would fill a 1 L beaker approximately how full? a. 1/8 b. 1/4 c. 1/2 d. 2/3 e. 3/4 How many centimeters long is a baby who is 20 in. long? ________________ INTRODUCTION TO BODY ORGANIZATION/METRICS e. 73 b. 1/4 50.8 cm ≈ 51 cm