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INFECTION CONTROL Understanding the basic principles of infection control is essential for any healthcare worker in any field of health care. Our essential question is: How are diseases transmitted and what are the main ways to prevent disease transmission? Principles of Infection Control Microorganism (or microbe) – small, living organism that is not visible to the naked eye. Found everywhere in the environment, including on and in the human body Nonpathogens – microorganism that is not capable of causing disease Pathogens – microorganisms that cause infection and disease Microorganisms can be beneficial in one body system and pathogenic in another body system EX: E. Coli – digestive system – normal flora urinary system - infection To grow and reproduce, microorganisms need: Warm environment - body temp ideal Dark environment Source of food Source of moisture Aerobic organisms require oxygen Anaerobic organisms live and reproduce in absence of oxygen Human body is ideal supplier of all requirements of microorganisms Main Classes of Microorganisms Bacteria Protozoa Fungi Rickettsiae Viruses Helminths Group Work Each group will be assigned a pathogen in which they will become experts on. Describe pathogen How are they classified? If possible, describe their shape? What diseases does this pathogen cause? What is some other interesting info you would like to share? Bacteria Simple one-celled organisms Multiply rapidly Classified by shape and arrangement Cocci Bacilli Spirilla Antibiotics are used to kill bacteria Bacteria Cocci Round or spherical in shape If occurs in pairs – diplococci Cause diseases such as gonorrhea, meningitis, pneumonia If occur in chains – streptococci Causes diseases such as strep throat and rheumatic fever If occur in clusters - staphylococci Bacteria Cocci (cont’d – Staphylcocci) Most common pyogenic (pus-producing) microorganisms. Cause infections such as boils, wound infections, and toxic shock. Bacteria Bacilli Rod-shaped bacteria Occur singly, in pairs, in chains Many contain flagella (threadlike projections similar to tails – allow to move) Have ability to form spores (thick- walled capsules) when conditions for growth are poor. In spore form, bacilli extremely difficult to kill Bacteria Bacilli (cont’d) Causes diseases such as tuberculosis, tetanus, pertussis, botulism, diphtheria, typhoid Bacteria (Spirilla) Comma shaped and corkscrew shaped Causes diseases such as syphilis and cholera Application: pg. 366 1. Divide paper in thirds 2. Label the first column Cocci Bacteria, second column Bacilli Bacteria, third column Spirilla Bacteria. 3. Draw a diagram of each type of bacterial shape indicating 4 types of cocci, 3 types of bacilli, and 3 types of spirilla 4. Label diagrams 5. List at least 5 diseases caused by cocci and bacilli, and 2 diseases caused by spirilla Protozoa One-celled animal like organism Usually found in decayed materials and contaminated water, animal or bird feces, insect bites Many contain flagella to allow them to move freely Cause diseases such as malaria, amebic dysentary, trichomonas (STD) , African sleeping sickness Protozoa (Malaria) Fungi Small, plant-like organisms Live on dead organic matter Yeasts and molds are 2 common forms Causes diseases such as ringworm, athlete’s foot, thrush, yeast vaginitis Antibiotics do not kill fungi Antifungal medicines - expensive, long course of treatment, may cause liver damage Rickettsiae Parasitic microorganisms (cannot live outside the cells of another organism) Found in fleas, ticks, lice, and mites and transmitted to humans by the bites of the insects Causes diseases such as Rocky Mountain Spotted Fever Treat with antibiotics Viruses Smallest microorganism– visible only with electron microscope Cannot reproduce unless inside another living cell Spread from human to human by blood and other body secretions Can be resistant to disinfectants Antibiotics not effective Virus (cont’d) Causes diseases such as common cold, measles, mumps, chickenpox, herpes, warts, influenza, polio 3 diseases of major concern to healthcare worker: Hepatitis B Hepatitis C AIDS New and different viruses emerge constantly because viruses are prone to mutating and changing genetic information. Viruses that infect animals can mutate to infect humans – often fatally Examples: SARS (severe acute respiratory infection), West Nile Virus, monkeypox, Ebola HIV and Flu Viruses Viruses of Special Concern to the Healthcare Worker Hepatitis B Hepatitis C AIDS Hepatitis B Caused by HBV virus Transmitted by blood, serum and other secretions Affects liver – can lead to destruction of liver cells Can remain active for several days in dried blood Vaccine available – expensive – series of 3 By law, employers must provide vaccine to healthcare worker for free Hepatitis C Caused by HCV virus Transmitted by blood or blood-containing fluids No vaccine available Patients often asymptomatic or mild flu symptoms Can cause liver damage Extremely difficult to destroy Can remain active for several days in dried blood AIDS Acquired Immune Deficiency Syndrome Caused by HIV (human immunodeficiency virus) Suppresses immune system Cannot fight off cancers or infections that would not normally affect healthy person No cure No vaccine Microorganisms need certain things to grow and reproduce: Most prefer a warm environment – body temp Most prefer darkness Most need food Most need moisture Aerobic organisms – are organisms which require oxygen to live Anaerobic organisms – do not require oxygen Microorganisms can produce toxins: Toxins = poisons Ex: tetanus produces a toxin that damages the CNS (central nervous system) Helminths Multicellular parasitic organisms Called worms or flukes Transmitted to humans when humans ingest the eggs or larvae in contaminated food, ingest meat contaminated with worms, or the worm penetrates the skin. Examples of Helminths: Hookworms – attach to small intestine and can infect heart and lungs Ascariasis – live in small intestine and can cause obstruction of the intestine Trichinella spiralis – causes trichinosis contracted by eating raw or inadequately cooked pork Enterobiasis (pinworms) mainly affects young children Hookworm in intestine Hookworm beneath skin ascriasis Trichinella spiralis 4 Classifications of Infectious Diseases Endogenous Exogenous Nosocomial Opportunistic Endogenous - infection /disease originates in body . Ex: tumor, congenital abnormality Exogenous – infection/disease originates outside body. Ex: pathogenic organisms that invade body Nosocomial infection – infection acquired by an individual in a healthcare facility. Ex: staph Opportunistic – occurs when the body’s defenses are weak. Ex: Kaposi’s sarcoma Chain of Infection: For diseases to occur and spread from one individual to another, certain conditions must be met… Chain of Infection Causative agent Reservoir Portal of exit Mode of transmission Portal of entry Susceptible host Causative Agent: A pathogen: Bacteria Virus Fungi Protozoa Rickettsiae Helminth What causes the infection/disease? Reservoir: A place where the pathogen can live: Human body Animals Environment Fomites (objects contaminated with infectious material) Ex: door knobs, linens, instruments, etc Portal of Exit: A way to escape from the reservoir where it has been growing urine Feces Saliva Tears Blood Draining wounds Mucous discharge Mode of Transmission: Way it can be transmitted to another reservoir or host where it can live. Direct person to person contact Direct contact with body secretion containing pathogen Ex: contaminated hands Indirect contact such as food, air, soil, insects, feces, clothing, instruments and equipment Portal of Entry: Way to enter a new reservoir or host Breaks in skin Breaks in mucous membranes Respiratory tract Digestive tract Circulatory system If the defense mechanisms of the body are intact and functioning, a human can frequently fight off the causative agent and not contract the disease. Susceptible Host: Person likely to get an infection Application: Using your textbook, pg 370, identify 8 Body Defenses that work to prevent a causative agent from entering the human body. Give an example of each Identify how each defense mechanism prevents the causative agent from entering the body Body Defenses Mucous membranes Cilia Coughing and sneezing Hydrochloric acid – in stomach Tears in the eye Fever Inflammation (WBC destroy pathogens) Immune response (antibodies) Scenario: Flu is caused by the influenza virus. Anyone can get the flu, which is a viral infection that attacks the respiratory system including your nose, throat, bronchial tubes and lungs. You’re especially at risk if you’re older, have diabetes, chronic heart disease or an impaired immune system. Someone you know has the flu, coughs and sneezes and then you touch something they’ve handled. That’s why the flu spreads anywhere people congregate…schools, cruise ships, day cares, etc. Identify the: Causative agent Reservoir Portal of exit Mode of transmission Portal of entry Susceptible host E. coli is short for Escherichia coli—a germ that causes severe cramps and diarrhea. E. coli is a leading cause of bloody diarrhea. The symptoms are worse in children and older people, and especially in people who have another illness. E. coli infection is more common during the summer months and in northern states. Healthy beef and dairy cattle may carry the E. coli germ in their intestines. The meat can get contaminated with the germ during the slaughtering process. When beef is ground up, the E. coli germs get mixed throughout the meat. The most common way to get this infection is by eating undercooked hamburgers. You can be infected with the E. coli germ if you don’t use a high enough temperature to cook your beef, or if you don’t cook it long enough. When you eat undercooked beef, the germs enter your stomach and intestines. If any part of the chain of infection is eliminated, the spread of disease or infection will be stopped. Healthcare workers must understand chain of infection to interrupt or break the chain and prevent spreading of disease. Pathogens are everywhere ….preventing their transmission is an ongoing process Ways to Break Chain of Infection Contamination – organisms and pathogens are present Aseptic techniques – maintaining cleanliness, and eliminating or preventing contamination Examples of common aseptic techniques: Handwashing Good personal hygiene Disposable gloves Proper cleaning of instruments Thorough cleaning of environment Levels of Aseptic Control Antisepsis – antiseptics prevent growth of pathogens….not effective against spores or viruses. Can be used on skin (alcohol, betadine) Disinfection – process that destroys or kills pathogens…sometimes effective against spores or viruses. Usually used on objects and not skin (disinfectants such as bleach) Sterilization – destroys all microorganisms including spores and viruses (autoclave) How to use an Autoclave Application: 1. Draw the chain of infection 2. Label each of the 6 sections of the chain of infection and define each link. Also give an example of each link. 3. Identify 3 ways to break each section of the chain of infection Make your poster colorful, creative and informative Page 370 Bioterrorism Bioterrorism is the use of microorganisms or biological agents as weapons to infect humans. Major concern of biological agents used not only in wars, but also against unsuspected civilians (ex: mail attack with anthrax) Could cause an epidemic and public health emergency Every healthcare worker must be alert to the threat of bioterrorism Application: Read pages 371-373 on Bioterrorism. Complete worksheet. Handwashing Handwashing is the most important method used to practice aseptic technique. Most effective way to prevent spread of infection. Hands are perfect medium for the spread of pathogens. Proper handwashing helps prevent and control spread of pathogens AND protects health worker from disease and illness. When should you wash hands? Before and after every patient contact Anytime hands become contaminated during procedure Before applying and immediately after removing gloves CDC recommendations for handwashing: Regular handwashing – soap and water; routine cleansing of hands when hands are visibly dirty or soiled with blood/body fluids Antiseptic handwashing – antimicrobial soap and water; before invasive procedures, critical care units, specific organism transmission based precautions Antiseptic handrubs – alcohol based hand cleaners – ONLY if hands are not visibly dirty and are not soiled with blood/body fluids Principles of Handwashing Soap Warm water Friction Clean all surface areas Point fingertips downward Use paper towels to turn faucet off and on Clean nails also Proper Handwashing Tips: Soap – preferably dispenser – sudsy action/alkali content removes germs Warm water – creates better lather than cold Friction – rubs off pathogens from skin surface Clean all surface area of hands Point fingertips downward Dry paper towels to turn faucet on and off – pathogens can travel through wet paper towel Clean nails – brush or rubbing against palms Soap Used as a cleansing agent Aid in removal of germs through sudsing and alkali content Pathogens trapped in soap suds and rinsed away Liquid soap better than bar soap Warm water Less damage to skin than hot water Increases lather of soap better than cold water Friction Must use friction - rubs off pathogens from surface of skin Rub hands together using friction for approximately 20 seconds. Clean all Surfaces Clean all surfaces of hands – including palms, back and tops of hands, between fingers. Nails Nails must be cleaned with an orange/cuticle stick, brush, or rubbing the nails against the palm of the opposite hand. Nails must be kept short to prevent scratching the skin, injuring patients, breaking through gloves. Point Fingertips Downward Keep fingertips pointed downward. Downward direction prevents water from going up forearms and then running down to contaminate clean hands. Turn faucet off with dry paper towels Dry paper towels must be used to turn faucet off. This prevents the contamination of the hands from pathogens on the faucet. Pathogens can travel easier through a wet paper towel than a dry paper towel. Application: Head to sinks to practice! Standard Precautions Standard Precautions – rules developed by the CDC to prevent the spread of infection Every body fluid and every patient is considered a potential source of infection OSHA developed: Bloodborne Pathogen Standard Needlestick Safety Act Application: Read pg 377 Bloodborne Pathogen Standard What are the 3 pathogens of major concern to healthcare workers? Who created the Bloodborne Pathogen Standard? What is PPE and what is an employer’s responsibility regarding PPE? Application: Read pg 377 Needlestick Safety Act Who developed the Needlestick Safety Act? Why was this act passed? List 4 requirements of employers regarding the Needlestick Safety Act. Give an example of each. Standard Precautions Basic rules of standard precautions: Hand hygiene Gloves Gowns Masks and eye protection Sharps Spills and splashes Resuscitation devices Cont’d Waste and linen disposal injuries PPE PPE – Personal Protective Equipment Donning PPE Gown Mask Goggles Gloves Removing PPE Gloves Gown Eyewear Mask Application: Read pgs 385—387 Sterilizing with Autoclave Read pgs. 392-393 Using Chemicals for Disinfecting Read pgs. 394-395 Cleaning with an Ultrasonic Cleaner Describe each method. Sterile Technique Sterile = free from all pathogens Contaminated = pathogens present Sterile field – never reach across a sterile field What is the difference between clean and sterile? Create a double bubble map comparing and contrasting using an autoclave vs. disinfecting with chemicals. How to don sterile gloves Transmission-Based Isolation Procedures Communicable disease – a disease which is caused by a pathogen which can easily be transmitted to others. Read pg 408 What is the difference between a pandemic and an epidemic Epidemic – occurs when communicable disease spreads rapidly from person to person and affects a large number of people at the same time Pandemic – exists when the outbreak of disease occurs over a wide geographical area and affects a large portion of the population Transmission-Based Isolation Precautions Methods or techniques of caring for people with communicable diseases Ex: TB, whooping cough, wound infections Standard Precautions are used on all patients Transmission –Based Isolation techniques are used to provide extra protection against specific diseases. The type of transmission –based isolation precaution used depends on the diseaes Application: Read pgs.409-413 Create a double bubble map which compares and contrasts 2 types of transmission-based isolation precautions Airborne Precautions Patients who are infected with pathogens transmitted by airborne droplet nuclei Ex: measles (rubella), varicella (chicken pox), TB Precautions: door kept closed, healthcare providers and visitors wear HEPA mask Pt wears surgical mask if leaves room Droplet Precautions Pt infected with pathogens transmitted by large-particle droplets expelled during coughing, sneezing, talking,etc Ex: flu (influenza), meningitis, pneumonia Private room Masks Contact Precautions Pt infected with pathogens that can be easily transmitted by either direct or indirect contact Ex: gastrointestinal, respiratory, skin or wound infections Private room, gloves, gown, linens changed daily Reverse Isolation Methods used to protect certain patients from microorganisms Used mainly for immunocompromised pts Ex: transplant pts, chemotherapy , severely burned pts, weak immune system Place in room that has been cleaned and disinfected, gloves, gown, mask, frequent disinfecting of room, special filters may be used to purify air.