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Understand terminology associated with oncology diagnosis and staging Describe common oncology pathologies and how the diagnosis impacts functional mobility and independence Identify early warning signs of cancer Discuss the role of the PTA in education and prevention of disease Discuss therapeutic interventions and precautions/contraindications for patients with an oncology diagnosis Describe special considerations when treating patients receiving chemotherapy or radiation therapy Invasive Second leading cause of death in U.S. Etiology unknown ◦ ◦ ◦ ◦ Environmental or viral carcinogens Genetic Dietary Psychological Unusual bleeding/discharge Unexplained lump Non-healing sore Persistent hoarseness/cough Difficulty swallowing/indigestion Change in a mole’s appearance Unexplained weight loss Unexplained pain Benign: non-invasive Malignant: invasive ◦ ◦ ◦ ◦ Carcinoma Sarcoma Lymphoma Leukemia and myeloma Metastasis: invades into another part of the body TNM classification Tumor, (lymph) Node, Metastasis Stages I-IV indicate severity overall ie: T2, N1, M1 Surgery Radiation Chemotherapy Immunotherapy (interferon, stem cells, etc.) Local and systemic effects of treatments Radiation burns, sickness, CNS effects GI concerns, immunosuppression, neuropathies with chemotherapy Fatigue, nutritional deficits, fever, low blood counts WBC: 5000 – 10,000 RBC: 4.7–6.1 million (male); 4.2-5.4 (female) Hct: 42-52% male; 37-47% female Hemoglobin: 14-18 male; 12-16 female Platelet Count: 150,000-450,000 Significance of too high or too low? Impact on exercise/activity level Low WBC: immunosuppressed High WBC: fighting infection; leukemia Low RBC: anemia, bleeding High RBC: pulmonary fibrosis, dehydration Low Hct: anemia, leukemia High Hct: burns, polycythemia, dehydration Low Platelet count: risk for bruising/bleeding High Platelet count is often a sign of malignancy RBC, Hemoglobin and Hematocrit will be elevated WBC will be elevated BUN will be elevated Palliative care (symptom management vs. curative management) Hospice Multidisciplinary Support in the form of psychological, emotional, financial, spiritual, social, etc. Unknown length of time Use of modalities? Primary or metastatic Symptoms based on the part of the brain affected Occurs in females and males If recurs, usually within the first 2 years Current 5 year survival rate is 92% if tumor is localized Patient education for self exams Symptoms include pelvic and low back pain Good prognosis with early intervention Patient education for annual pap smears 15% of cancer deaths annually High fat/low fiber diet is risk factor Presents with fatigue, weight loss, anemia, rectal bleeding Good prognosis with early detection and treatment Patient education to follow recommended screenings Immature white blood cells multiply and halt the growth of normal cells ALL (acute lymphocytic leukemia) and AML (acute myeloid leukemia) occur mostly in children Sudden onset fever, fatigue, joint pain Blood work confirms diagnosis 90% remission of ALL, 70-80% of AML Rapidly metastasizes Environmental and genetic risk factors Early signs include cough, dyspnea, hemoptysis Poor prognosis (14% for 5 year survival) Non-Hodgkin’s more common Cancer in the lymphatic system Risk factors are environmental, viral, and auto-immune disease Distinguished by the types of cells present (Reed-Sternberg cells = Hodgkin’s) Highly treatable Found in epiphyses of long bones Common in children Signs include a painful mass, diagnosis with a biopsy Amputation or limb-salvage surgical procedures Rehab High mortality rate, high rate of metastasis Symptoms include weight loss, jaundice, and epigastric pain Poor prognosis Men over 50 yo typically affected Symptoms include urinary urgency, pain, and decreased stream of urine Good prognosis with early treatment Preventative/Pre-diagnosis Education Be aware of red flags or pain that doesn’t correlate with musculoskeletal diagnosis Listen to your patient and their complaints Refer to PT when suspicious/concerned Monitor typical vs. atypical pain pattern Vital sign monitoring Monitoring of lab values and blood counts Submaximal level of exercise RPE not above 12 Report changes immediately to PT ◦ Progressive muscle weakness ◦ Diminished DTRs ◦ Cerebellar impairments Low blood counts: “My counts are low” WBCs: increased infection risk RBCs: anemia/decreased aerobic capacity Platelets: increased bleeding/bruising (no ex. if <20,000) Patients may have restrictions on activity level or weight bearing. Consult with PT/MD Education and support Skin care and protection Edema control and positioning Pain control Massage AROM/PROM exercises Strengthening Cardiovascular endurance (submaximal) ADLs and functional mobility and ambulation Coordination and balance training Pacing and energy conservation Specific post-op protocols (BMT, mastectomy) Modalities within contraindications Avoid strenuous activities (40-65% HRmax) Be aware of fatigue level Skin care Awareness of skin tatoos for radiation Contraindications of modalities Be aware of sensory impairments and peripheral neuropathies Cognitive impairments (chemo brain)