Download Medicines and falls

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project

Document related concepts

Harm reduction wikipedia , lookup

Pharmacognosy wikipedia , lookup

Quackery wikipedia , lookup

Transcript
Medicines and falls
Assessing the impact of medicine on
falls risk
Presenter notes:
This presentation is designed for registered nurses, but may be applicable to all nursing staff at
the aged care facility. It is part of a series of four presentations on medicine and falls.
The first presentation examined common causes of falls, and the impact and cost of falls on the
individual and the community. This second presentation will discuss medicines that increase the
risk of falls. The third presentation will identify intervention strategies to reduce medication
related falls. The final presentation looks at the role of the pharmacist in preventing falls.
Medicines have been shown to contribute to an increased risk of falling in a number of
epidemiological studies. The risk may be increased by medication interaction, unwanted side
effects (such as dizziness) or the desired effects of medicines such as sedation.
Residential aged care facilities (RACFs) staff and the whole health care team need to recognise
that pharmacological changes that occur with ageing may lead to potentially avoidable events in
older people, including falls and fractures. This presentation will discuss the use of multiple
medicines, including psychoactive medicines, and the contribution they make to the resident’s
risk of falling.
Reference
Preventing Falls and Harm From Falls in Older People. Best Practice Guidelines for Australian
Residential Aged Care Facilities 2009
www.safetyandquality.gov.au/internet/safety/publishing.nsf/content/compubs_FallsGuidelines/$File/Guidelines-RACF.PDF
1
Learning objectives
• Recognise the causes, impact and cost of falls
• Identify the effects of medicine that may result
in a fall
• List medicines that may be a falls risk
• Understand possible falls prevention strategies
and changes to medication regimens and
dosage forms that can be made to minimise the
risk of falls
• Describe the role of the pharmacist in falls
minimisation
Presenter notes:
All the learning objectives for the four presentations of Medicines and falls are listed on the
slide. This presentation will focus on identifying the causes of falls, the effects of medicine that
may result in a fall and listing those medicines that may be a falls risk.
2
Medication and falls in RCFs
• Medication use is common in residential care
facilities (RCF)
– 98% of residents take at least one medicine
– 63% take >4 medicines
• Medication use is associated with falls, with one
study finding increase relative risk of falling;
– 1.4 times greater with 1 medicine
– 2.2 fold greater for 2 medicines
– 2.4 fold greater for >3 medicines
Presenter notes:
The use of medicines and the risk of falls is an important consideration for residential care
facilities (RCF) staff. Medication use, in particular use of multiple medicines, is commonplace in
RCFs with 63% of residents taking more than 4 medicines. The use of medicines has been
associated with increased risk of falls. Compared to residents who are not using medicines, the
risk of falling is
• 1.4 times greater with 1 medicine used
• 2.2 fold greater for 2 medicines used
• 2.4 fold greater for >3 medicines used
Reference:
Preventing Falls and Harm From Falls in Older People. Best Practice Guidelines for Australian
Residential Aged Care Facilities 2009. Available at
www.safetyandquality.gov.au/internet/safety/publishing.nsf/content/compubs_FallsGuidelines/$File/Guidelines-RACF.PDF
3
Risk Factors for medication related falls
• Taking 4 or more medicines
• Starting or stopping a
medicine
• Dose changes
• Having trouble remembering
to take medicine leading to
missed doses or doubling up
• Alcohol consumption
Presenter notes:
Certain factors may increase the risk of medication related falls in RCF residents.
Evidence has shown that elderly people taking four or more medicines are at high risk of falling,
and as we have seen earlier up to 63% of RCF residents take >4 medicines. The risk of adverse
(unwanted) drug effects and interactions with other drugs increases with number of medicines
taken, and this may contribute to the increased risk of falls.
The risk of falls is also increased when starting or stopping a medicine, or after a dose change.
A new medicine or lowering/increasing a dose of a medicine can alter the way a person feels
e.g. dizziness, sedation, therefore extra care is indicated to prevent a fall.
Missing doses and getting mixed up with which medicine to take at what time can also cause a
fall. Alcohol has also been shown to be a risk factor for a fall as it can also interact with the
medicines that a person is taking.
Care notes
Any resident who is taking four or more medicines and is self-medicating is a potential falls risk.
Monitor this resident closely. Care should be taken if the resident has a number of different
healthcare providers e.g. a GP, a medical specialist, a hospital doctor, to ensure each medicine
prescribed is indicated and appropriate. The pharmacist can assist in reviewing a residents
medication via a RMMR.
Reference:
Tinetti ME. Preventing Falls in Elderly Persons. New England Journal of Medicine.
2003;348(1):42-49.
4
Falls - medicine and age
• Age-related changes
– Renal function decline
– Increased sensitivity to drug effects
• Poly-pharmacy
• Non-compliance due to:
– Regimen complexity
– Language difficulties
– Swallowing difficulties
– Attempt to minimise adverse effects
– Potential cost saving
Presenter notes:
The elderly are often more susceptible to medicine-related falls due to age-related changes.
Medication problems can be associated with:
•
•
•
•
Pharmacokinetic changes (how the body absorbs, distributes, metabolises and excretes
drugs) - most important effect of ageing is reduction in renal function which results in
reduced elimination of both renally excreted drugs and active drug metabolites. If a dose
is not altered to reflect a reduction in renal function, adverse drug effects may occur
potentially causing a fall;
Pharmacodynamic changes (the effect of drugs on cellular and organ function) sensitivity to the effect of drugs changes with age as drug receptors and target organ
responses can change. This may be seen by increased central nervous system (CNS)
effects of psychoactive medicines such as benzodiazepines and opioids which can result
in falls amongst other effects. The body’s compensatory mechanisms may be affected
by age resulting in drug adverse effects e.g. orthostatic (postural) hypotension may
occur with diuretics or tricyclic antidepressants (TCAs) causing a person to fall;
Poly-pharmacy - elderly patients often take many medicines increasing the risk of
adverse drug effects and interactions. Residents may have both a GP and specialist(s)
who prescribe drugs as well as drugs brought in from hospital stays and family. They
also may be taking over-the-counter(OTC) medicines, drugs for a previous illness, or
even drugs prescribed for another person. A medication review by an accredited
pharmacist may be necessary to confirm exactly what is being taken; and
Non-compliance – may be unintentional as a result of confusion or forgetfulness. This
can occur due to regimen complexity, language difficulties, swallowing difficulties.
5
Intentional non-compliance can occur in an attempt to minimise adverse effects or to
save money. This will be more common for residents who self-administer.
The use of drugs in the elderly must be carefully planned and monitored because age-related
changes in pharmacokinetics and pharmacodynamics, as well as the risks of polypharmacy and
non-compliance, predispose the elderly to adverse drug reactions.
Care notes
Residents in residential aged care services have the right to administer some, or all, of their own
medicine. In order to meet duty of care and accreditation requirements and to optimise resident
care, it is recommended that RACF maintain some form of record of these medicines. This may
be in the form of a medication record indicating that the resident is self-administering, or a card,
which is updated as medicine changes occur. The medicine advisory committee (MAC) should
develop a policy regarding the procedures to be used when a resident chooses to selfadminister medicine. A resident who is self-administering should be regularly assessed.
References:
• Rossi S. Australian Medical Handbook [online] Prescribing for the elderly 2012
• Preventing Falls and Harm From Falls in Older People. Best Practice Guidelines for
Australian Residential Aged Care Facilities 2009. Available at
www.safetyandquality.gov.au/internet/safety/publishing.nsf/content/compubs_FallsGuidelines/$File/Guidelines-RACF.PDF
• Resource Kit to enable implementation of the APAC Guidelines for Medication
Management in Residential Aged Care Facilities. Guidelines for management of
residents who administer their own medicines (self-administration).
www.health.vic.gov.au/dpu/resource-kit.htm
6
Causes of medicine related falls
•
•
•
•
•
•
•
•
•
Agitation
Balance problems
Blurred vision
Confusion
Dizziness
Drowsiness
Gait problems
Syncope
Urgency
Presenter notes:
Some medicines cause effects that have been implicated in falls either as an intentional effect
(e.g. sedation) or as an adverse drug effect (e.g. dizziness). Listed on the slide are some effects
of medicines that may cause a patient to fall while taking certain medicines.
(Syncope - temporary loss of consciousness caused by a fall in blood pressure)
References:
• Ruddock B. Medications and Falls. CPJ/RPC 2004;137(6):17-18.
• Preventing Falls and Harm From Falls in Older People. Best Practice Guidelines for
Australian Residential Aged Care Facilities 2009
www.safetyandquality.gov.au/internet/safety/publishing.nsf/content/compubs_FallsGuidelines/$File/Guidelines-RACF.PDF
7
Medicines that increase the risk of falls
Effect of
medicine
Medicine
Agitation
antidepressants, antipsychotics, stimulants
Balance
anticonvulsants, antipsychotics, prochlorperazine
Blurred vision
eye drops, anticholinergics, any drug with anticholinergic effects
Confusion
opioids, psychotropics, any drug with anticholinergic effects
Dizziness
blood pressure medications, diuretics, any drug with anticholinergic
effects
Drowsiness
psychotropics, anticonvulsants, any drug with anticholinergic effects
Gait abnormalities antidepressants, antipsychotics, metoclopramide
Syncope
blood pressure medications, vasodilators
Urgency
diuretics
Presenter notes:
Which medicines can cause these effects?
There has been a number of studies that have shown an association between medication use
and falls in older people. Some medicines have been studied more than others. Although many
medicines are suggested as implicated in falls, strong evidence only exists to suggest that
psychotropic medicines (e.g hypnotics, anxiolytics, antidepressants and antipsychotics) are
involved. There is less evidence for those medications lowering blood pressure. It is suspected
other medicines such as anticonvulsants, opiate pain medicines and those medicines with
anticholinergic side effects such as blurred vision, confusion, dizziness and drowsiness are also
implicated.
A variety of medication categories may predispose an individual to falls.
Some examples are:
• Antidepressants may cause side effects such as sedation, lethargy, confusion, double
vision, motor incoordination, dizziness, and weakness;
• Medicines that have significant anticholinergic effects such as antihistamines,
metoclopramide, promethazine, muscle relaxants, and medicines used to treat urinary
incontinence (oxybutynin and tolterodine) may cause sedation, confusion, a lack of
coordination, or dizziness;
• Many anti-parkinson’s agents may result in dyskinesia, confusion, and delirium, which
can increase the risk of falling;
• Medicines used chronically to treat hypertension, parkinson’s disease, and angina can
result in orthostatic hypotension-related falls;
8
•
•
•
Psychotropic drugs (hypnotics, anxiolytics, antidepressants, antipsychotics) have been
shown to increase the risk of falls particularly in older adult patients;
Analgesics, including both opioid and nonsteroidal anti-inflammatory drugs (nsaids); and
Anticonvulsants.
In this presentation we are going to focus on drugs with anticholinergic effects,
benzodiazepines, antidepressants, diuretics, blood pressure medicine and alcohol.
Care notes
Since many medicines may exert an effect that could result in a fall, ensure there is a list of
these medicines is displayed.
Residents who self-administer their medicines need to be educated on the effects of their
medicines to avoid a fall.
References:
• Lindsey P. Psychotropic Medication Use among Older Adults: What All Nurses Need to
Know 2009 [accessed online] www.ncbi.nlm.nih.gov/pmc/articles/PMC3128509/
• Preventing Falls and Harm From Falls in Older People. Best Practice Guidelines for
Australian Residential Aged Care Facilities 2009
www.safetyandquality.gov.au/internet/safety/publishing.nsf/content/compubs_FallsGuidelines/$File/Guidelines-RACF.PDF
9
Drugs with anticholinergic effects
Anticholinergic effects
Drugs that exert anticholinergic effects
Blurred vision with dilation of
pupils
•Drugs for urinary incontinence
Dry mouth
•Antispasmodics and antidiarrhoeals
Constipation
•Antipsychotics
Delirium or central excitation
•Tricyclic antidepressants
Dizziness
•Drugs for Parkinson's disease and to treat
Glaucoma worsening
extrapyramidal side effects
Hallucinations or euphoria
•Bronchodilators
Hyperpyrexia
•Drugs for eye examinations
Urinary hesitancy or
obstruction
•Other drugs such as disopyramide, mianserin,
•Antihistamines
pizotifen, prochlorperazine
Presenter notes:
Let’s start with drugs that exert an anticholinergic effect. Anticholinergic effects are physical
symptoms that result from medicine that opposes the action of acetylcholine, a neurotransmitter
(chemical within the nervous system). These anticholinergic effects typically act peripherally and
centrally and are dose related. Medicines that have significant anticholinergic effects, such as
antihistamines, promethazine, muscle relaxants, and medications used to treat urinary
incontinence (oxybutynin and tolterodine) may cause both peripheral and central effects.
Peripheral effects: dryness of mouth, dilatation of pupils, flushing, worsening of glaucoma,
urinary hesitancy or obstruction, constipation, paralytic ileus, nausea and blurred vision.
Central effects: dizziness, hallucinations, euphoria, hyperpyrexia and central excitation. Older
people are more susceptible to central adverse effects such as delirium.
All of these effects may contribute to an increased risk of falls.
Examples of drugs that exert anticholinergic effects
Drugs for urinary incontinence - darifenacin, oxybutynin, propantheline, solifenacin, tolterodine
Antihistamines - brompheniramine, chlorpheniramine, dexchlorpheniramine, dimenhydrinate,
diphenhydramine, pheniramine, promethazine, trimeprazine
Antispasmodics and antidiarrhoeals - belladonna alkaloids, hyoscine (butylbromide or
hydrobromide), loperamide
Antipsychotics - chlorpromazine, clozapine, fluphenazine, olanzapine, pericyazine,
trifluoperazine
Tricyclic antidepressants - amitriptyline, clomipramine, dothiepin, doxepin, imipramine,
nortriptyline[E], trimipramine
10
Drugs for Parkinson's disease and extrapyramidal disorders - amantadine, benzhexol,
benztropine, biperiden, orphenadrine
Bronchodilators - ipratropium (nebulised), tiotropium
Drugs for eye examinations - atropine, cyclopentolate, homatropine, tropicamide
Other - disopyramide, mianserin, pizotifen, prochlorperazine
References:
• Therapeutic Guidelines Psychotropic Drugs 2003 [update 2006 Apr]
• National Prescribing Service. NPS News 59: Drugs used in dementia in the elderly.
www.nps.org.au/health_professionals/publications/nps_news/current/nps_news_59_dru
gs_used_in_dementia_in_the_elderly
11
Benzodiazepines
Drug name
Product name
Duration of action
Alprazolam
Alprax, Kalma, Ralozam, Xanax
short acting
Diazepam
Atenex, Ranzepam, Valium, Valpam
long acting
Flunitrazepam
Hypnodorm
long acting
Lorazepam
Ativan, Lorazepam
medium acting
Nitrazepam
Alodorm, Mogadon
long acting
Oxazepam
Alepam, Murelax, Serepax
short acting
Temazepam
Normison, Temtabs, Temaze
short acting
Presenter notes:
Benzodiazepines are another group of drugs where use is a consistently reported risk factor for
falls and fractures in older people, both after a new prescription and over the long term. They
affect cognition, gait and balance. Benzodiazepines are most commonly prescribed for anxiety
disorders or symptoms (known as anxiolytics). Because of the increased susceptibility to
oversedation and memory and psychomotor impairment, elderly patients who take
benzodiazepines are more at risk for falls and skeletal fractures.
Medicines in this class have varying onset of action and duration as summarised below:
Very short acting (half-life <6 hours) — midazolam, triazolam.
Short acting (half-life 6–12 hours) — alprazolam, oxazepam, temazepam
Medium acting (half-life 12–24 hours) — lorazepam, bromazepam.
Long acting (half-life >24 hours) — clobazam, clonazepam, diazepam, flunitrazepam,
nitrazepam.
Rapid onset (<1 hour after oral administration) — alprazolam, diazepam, flunitrazepam,
midazolam, temazepam, triazolam.
Shorter acting agents (particularly those with rapid onset of action) are more likely to lead to
acute withdrawal symptoms. Diazepam's rapid onset of action and long half-life mean it is
associated with less withdrawal. Long acting agents, e.g diazepam, clonazepam, are preferred
when using benzodiazepines as prophylaxis against withdrawal from alcohol, barbiturates or
other benzodiazepines.
12
Care notes
Resident’s using short acting agents for sleep should be discouraged from rising from bed after
dose has been taken.
Reference:
• Rossi,S. Australian Medical Handbook [online] 2012
• Preventing Falls and Harm From Falls in Older People. Best Practice Guidelines for
Australian Residential Aged Care Facilities 2009
www.safetyandquality.gov.au/internet/safety/publishing.nsf/content/compubs_FallsGuidelines/$File/Guidelines-RACF.PDF
13
Antidepressants
Class
Drug name
MAO-I
phenelzine, tranalcypromine, moclobemide
SSRIs
citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine,
sertraline
TCAs
amitriptyline, clomipramine, dothiepin, doxepin, imipramine,
nortriptyline
Others
lithium , mianserin, mirtazapine, reboxetine, duloxetine,
desvenlafaxine , venlafaxine
Presenter notes:
Antidepressants are associated with higher falls risk specifically specific serotonin reuptake
inhibitors (SSRIs) and tricyclic antidepressants (TCAs) classes. However, the risk appears to be
dose related. They may cause side effects such as sedation, lethargy, confusion, double vision,
motor incoordination, dizziness, and weakness. All these effects can contribute to the risk of
falls.
Monoamine oxidase inhibitors (MAO-I) - used as a second line treatment for both major
depression and some anxiety disorders, including phobic disorders and panic disorder. They
must be used with caution in the elderly because of drug interactions and potential adverse
cardiovascular effects (particularly orthostatic hypotension).
Serotonin selective reuptake inhibitors (SSRIs) - a newer generation of this class of medicine,
have become the preferred first-line treatment for depression in older adults, as these drugs
have more benign side effects than other antidepressant agents. Side effects common to SSRIs
include headache, gastrointestinal disturbances, increased sweating, and sexual dysfunction.
Unlike other antidepressant drugs, SSRIs have fewer anticholinergic or cardiovascular effects.
However, older adults have increased sensitivity to SSRI adverse effects than do younger
patients.
Tricyclic antidepressant drugs (TCAs) - an older generation of antidepressant medicine, have
a number of side effects that increase elderly patients' risk for falls. These include sedation,
psychomotor retardation, postural hypotension, and anticholinergic effects, which may cause
blurred vision and cognitive impairment. Fall risk is the greatest during the first 90 days of
treatment, when dosages are being adjusted and before physiological adjustment has taken
place.
14
A recent study found that residents in aged care facilities who have dementia and take
antidepressants are significantly more likely to suffer an injury as a result of a fall compared to
residents who do not take these drugs. This risk of a fall is present even if the patient is only
taking low or moderate doses of the drugs. According to Dutch researchers, many people in
aged care facilities with dementia also have depression and so are treated with antidepressants.
References:
• Rossi, s. Australian Medical handbook [online] 2012.
• Preventing Falls and Harm From Falls in Older People. Best Practice Guidelines for
Australian Residential Aged Care Facilities 2009
www.safetyandquality.gov.au/internet/safety/publishing.nsf/content/compubs_FallsGuidelines/$File/Guidelines-RACF.PDF
• Dose-response relationship between Selective Serotonin Reuptake Inhibitors and
Injurious Falls: A study in Nursing Home Residents with Dementia Sterke C et al. British
Journal of Clinical Pharmacology.
www.irishhealth.com/article.html?id=20259acobson et al., 2007).
15
Diuretics
• Weakly associated with falls
• Can cause orthostatic hypotension by:
- lowering blood pressure
- volume depletion
Drug name
Product name
Frusemide
Frusid, Lasix, Uremide, Urex
Hydrochlorothiazide
Dithiazide, Hydrene (with triamterene),
Moduretic (with amiloride)
Presenter notes:
Diuretics are weakly associated with an increased risk of falls. Diuretics can have a direct effect
on blood pressure and can also cause volume depletion, which in itself can cause orthostatic
(postural) hypotension. Counsel the patient that they may feel dizzy on standing when taking
this medicine. Encourage the patient to get up gradually from sitting or lying to minimise this
effect; sit or lie down if you become dizzy.
This is an incomplete list of medicines for high blood pressure. The slide is intended for
discussion only.
References:
Rossi, S. Australian Medical handbook [online] 2012.
16
Blood pressure medicines
• Used to treat hypertension
• Elderly may experience first dose effect
• Adverse effects are hypotension, dizziness,
fatigue
Drug class
Example
ACE inhibitors
Perindopril (Coversyl)
Ramipril (Ramace, Tritace, Prilace, Tryzan)
Beta blockers
Atenolol (Noten, Tenormin, Tensig)
Presenter notes:
Drugs used to treat hypertension may predisposed elderly patients to first dose hypotension.
Adverse effects of antihypertensives that may increase falls risk include hypotension, dizziness,
fatigue. Advise the patient to get up gradually from sitting or lying to minimise this effect; sit or
lie down if you become dizzy or light-headed.
Medications and volume depletion are the two most common causes of postural hypotension in
older people. Although medicine commonly associated with postural hypotension include the
antihypertensive agents, you should also be aware that antianginals, antidepressants,
antipsychotics and antiparkinsonian medications and diuretics can all cause postural
hypotension possibly resulting in falls.
References:
• Rossi, S. Australian Medical handbook [online] 2012.
• Preventing Falls and Harm From Falls in Older People. Best Practice Guidelines for
Australian Residential Aged Care Facilities 2009
www.safetyandquality.gov.au/internet/safety/publishing.nsf/content/compubs_FallsGuidelines/$File/Guidelines-RACF.PDF
17
Other drugs of concern
• Corticosteroids
– Bone weakness
• Anti-coagulants
– Risk of haemorrhage
• Lithium
– Tremor, vertigo
Presenter notes:
These are some of the other drugs mentioned in the literature which are associated with falls.
Examples are:
• Corticosteroids: bone weakness can occur from prolonged corticosteroid use would
cause a potential injury risk if a fall occurs.
• Anticoagulants: may increase risk of haemorrhage if fall occurs, but studies show these
patients do not fall more than others.
• Lithium: common adverse effects of tremor and vertigo may contribute to risk of falling.
References:
Rossi, S. Australian Medical handbook [online] 2012.
18
Alcohol
• Drinking alcohol increases the risk of falls and
injuries
• Alcohol dependence may be mistaken for
depression, insomnia, poor nutrition and frequent
falls
• Remember a standard drink contains 10gm of alcohol
– = 100ml glass of wine
– = 30ml of spirits
– = 375ml of mid-strength beer
Presenter notes:
For some older adults, drinking alcohol increases the risk of falls and injuries, as well as some
chronic conditions. Population-based studies estimate that approximately 40 per cent of males
and 30 per cent of females aged over 60 years drink at a moderate level. The decline in alcohol
consumption in the older population is primarily associated with the onset of health problems.
Alcohol dependence may also be mistaken for medical or psychiatric conditions such as
depression, insomnia, poor nutrition and frequent falls. Also consider potential interactions with
medications.
A standard drink is any drink containing 10 grams of alcohol. One standard drink always
contains the same amount of alcohol regardless of container size or alcohol type (i.e. beer,
wine, or spirit).
Australian Guidelines to Reduce Health Risks from Drinking Alcohol : Guidelines 1 and 2 (total
of 4)
Guideline 1: Reducing the risk of alcohol-related harm over a lifetime: The lifetime risk of harm
from drinking alcohol increases with the amount consumed. For healthy men and women,
drinking no more than two standard drinks on any day reduces the lifetime risk of harm from
alcohol-related disease or injury.
Guideline 2: Reducing the risk of injury on a single occasion of drinking: On a single occasion of
drinking, the risk of alcohol-related injury increases with the amount consumed. For healthy men
and women, drinking no more than four standard drinks on a single occasion reduces the risk of
alcohol-related injury arising from that occasion.
19
References
• Australian Government. National Health and Medical Research Council.
www.nhmrc.gov.au/your-health/alcohol-guidelines Appendix 1[2011 July 13; cited 2012
Feb 2]
• The Australian Government – Department of Health and Ageing.
www.health.gov.au/internet/alcohol/publishing.nsf/Content/guidelines
• Australian Government. National Health and Medical Research
Councilwww.nhmrc.gov.au/_files_nhmrc/publications/attachments/ds10-alcoholqa.pdf
[2011 July 13; cited 2012 Feb 2]
• Australian Government. National Health and Medical Research
Councilwww.nhmrc.gov.au/your-health/alcohol-guidelines [2011 July 13; cited 2012 Feb
2]
• The Australian Government – Department of Health and Ageing.
www.health.gov.au/internet/alcohol/publishing.nsf/Content/standard Department of
Health and Ageing. The Australian Standard Drink [2009 Oct 21; cited 2012 Feb 02]
20
Mrs Sharpe
Prescribed medicines:
• Oxazepam 30mg 1 four
times daily
• Zolpidem 10mg ½ tab at
night
• Ramipril 10mg 1 morning
• Metformin 500mg 4 at night
• Crestor 5mg 1 night
15
Presenter notes:
Mrs Sharp is 86 and has recently been admitted to your RACF after the death of her husband.
She is unsteady when walking and her balance appears impaired.
Ask the group to:
• Review Mrs Sharpe’s medicines. Do any of the medicines pose a falls risk for Mrs
Sharpe?
Note: Mrs Sharpe is taking more than four medicines making her a falls risk; she is
taking Oxazepam 300mg 1 four times daily for anxiety and Zolpidem ½ tablets night for
insomnia. The concurrent use of multiple benzodiazepines or benzodiazepine-like drugs
(e.g. zolpidem) makes Mrs Sharpe a falls risk.
• What would you do now?
Note: Undertake a falls risk assessment; suggest a residential medication management
review.
21
Summary
• Residents using medicines, particularly > 4 medicines
are at increased risk of falls
• Medicine that increase falls risk are:
– Psychotropic drugs: hypnotics, anxiolytics,
antidepressants, antipsychotics
– Drugs which exert anticholinergic effects
– Antihypertensives
– Analgesics
– Anticonvulsants
– Others – corticosteroids, anticoagulants, alcohol
16
Presenter notes:
Be aware that certain classes of medicine are more likely to increase the risk of falls in older
people.
22
Any questions?
17
17
23