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II. Science and Evolution A. Characteristics of a good scientific theory 1. TESTABLE: Must make predictions; must be falsifiable a. Karl Popper: One cannot prove something is true, but can prove that something is false b. Methodology (1) Null hypothesis (a) What is tested/rejected (b) Example: APenicillin has no effect upon bacterial infections@ (2) Control (a) Standard of comparison (b) Experimental treatment omitted (c) Placebo: Inactive substance (d) Placebo Effect: Response to act of being treated (3) Variables (a) Independent i) Affects something ii) X-axis (b) Dependent i) Affected by independent variable ii) Y-axis Picture Slide #1: (A) Growth of the larval stage of a tapeworm in an intermediate host (mice) (B) Growth of infected and uninfected hosts (mice). Fig. 1-3 in handout Smith (1994) 2. Repeatable a. Others get similar results b. Data are reliable, not faked 3. Stable: Theory unchanged after repeated testing 4. Simple a. Parsimony b. Ockham=s Razor: If 2 hypotheses explain the facts, choose the most simple c. Doubt hypotheses with many exceptions 5. Non-authoritarian a. Authoritarian: The world is round because . . . (1) My parents told me (2) My teacher told me (3) My textbook says so b. Rational (= non-authoritarian): The world is round because . . . (1) The earth=s shadow on the moon is round (2) The last structure seen as a ship sails below the horizon is the tallest mast. 6. No retro-fitting a. Technique used by Apsychics@ 6 APsychic@ makes a general statement (1) ASomeone you care about is ill@ (2) AYou are thinking about making a change in you life.@ c. Victim supplies the specific answer. (1) Almost everyone knows somebody ill (a) Uncle Bob broke his leg (b) Aunt Betty has cancer (c) My parasitology teacher should lower his cholesterol. (2) People constantly daydream about . . . (a) Taking a neat vacation (b) Getting a better job (c) Breaking up with his/her significant other d. APsychic@ police investigation Aclues@ (1) Information offered before criminal does not facilitate solving the crime (a) AI see the color red.@ (b) AI see the number 7" (c) AThere is water@ (2) After crime solved by traditional methods, Apsychic@ claims his/her clues were accurate descriptions (a) The criminal was wearing a red shirt, driving a red car, lived in an apartment with a red door when caught (b) The criminal lived near a 7/11, near Highway 73, was caught on the 17th day of the month, had a birthday in July. (c) It was raining the day of the arrest, there was a lake or stream nearby, someone was watering their lawn, the criminal was taking a shower. Supported by convergence of independent evidence a. Murder investigation (1) Suspect threatened victim in a letter (2) Murder weapon found in suspect=s home (3) DNA testing: Blood on suspect=s clothes matches that of victim (4) Footprints at crime scene match those of suspect (5) Witnesses saw suspect=s car at crime scene b. Evolution supported by information not known in Darwin=s lifetime (1) Fossil record records changes (2) Radio-isotope dating confirms age of earth (3) Nuclear physics/theory of relativity/constant speed of light/astronomical observations confirm that universe/solar b. 7. 7 system is old enough for evolution to have occurred (4) Continental drift (5) Mendelian genetics explains variation in populations (6) Molecular biology (7) Cladistic analysis B. Basic Concepts of Evolution 1. Individuals within populations have different traits = variation a. Mutation creates new genes b. Crossing over and independent assortment during meiosis create new associations/combinations of different genes 2. Genes enabling bearers to have more offspring become common in gene pool. a. Less than 1% of all organisms that are born ever reproduce b. Maladaptive genes are REMOVED from gene pool of population Picture Slide #2: Far Side Cartoon 3. Reproductively isolated groups eventually split into new sibling species 4. Mechanisms a. NATURAL SELECTION (1) Genes removed from population (2) Death before reproduction b. SEXUAL SELECTION (1) Females often choose male mate (2) May lead to exaggerated traits (= bright plumage) that increase risk of predation for male. C. Misconceptions about evolution 1. ASurvival of the fittest@ a. Inexact and trite b. Viable offspring much more important that simply Asurviving@ 2. Modern species are more Aadvanced@ or Abetter adapted@ than extinct species Picture Slide #3: Far Side Cartoon a. Many large scale extinctions were caused by extraordinary events to which organisms had no chance to adapt (1) Asteroid impacts (2) Sudden drastic changes climate due to continental drift influencing oceanic currents b. Dinosaurs were well-adapted to their environment 3. Over evolutionary time, species tend to increase in complexity a. Jettisoning a trait may increase energy available for reproduction b. Comparisons between parasites and their free-living relatives indicate that many parasites have lost some structures (= Tapeworms are without a gut.) c. Traits are continually being gained AND lost over evolutionary time 8 4. Parasites are degenerate organisms that are significantly less complex than their free-living relatives a. Parasites acquire traits different from free-living relatives which enable them to complete their life-cycles. (1) Infect new hosts (2) Avoid host=s immune system b. In many traits, parasites are more complex than their free-living relatives. (1) A typical trematode life-cycle can involve living in a vertebrate, a mollusk, and an arthropod Picture Slide #4: Life-cycle of a typical trematode worm. (2) Tapeworm integument is covered with microvilli that absorb nutrients D. Non-scientific hypotheses 1. Intelligent design (= ID) a. Argument for (1) Metabolic pathways, organisms, life-cycles are intricate and complicated (2) Therefore, they MUST have been designed or created by a powerful superior being. Picture Slide #5: Life-cycle of a butterfly; an example often used by creationists to support Intelligent Design Theory. b. Arguments against (1) Too many Apoorly@ designed structures (a) Connection between respiratory & digestive tracts of vertebrates (b) Neurons of vertebrate eye lie between incoming light and sensors (c) Human head does not pass easily through birth canal (2) Is ID a blasphemous concept? (a) Most (2/3s) organisms are parasites (b) Parasites are Awell-designed@ to infect hosts (c) Parasites have been Awell-designed@ to live inside hosts (d) Suffering induced by Aintelligently designed@ presents a moral dilemma Picture Slide #9: Human Schistosomiasis caused by a “well-adapted” trematode TELEOLOGY 2. a. Defined: Attributing purpose to descriptions of natural events b. Not testable c. Examples (1) Divine punishment for immoral life-style (a) Hurricanes hit Florida/Gulf Coast because voters 9 3. legalized gambling (b) Diseases such as AIDS and STDs (2) Giraffes have long necks in order to eat leaves at the top of trees (3) Since large snails are more likely to be seen and eaten by predators, it is beneficial for the snail population to produce a supply of large snails for this purpose in order that the small snails (= next generation) are not eaten ANTHROPOMORPHISM a. Defined: Attributing human emotions to animal activities and behaviors b. Examples (1) Mother lion loves her offspring so much that she will risk her life to defend them (2) Porpoises like humans (3) Female snail wants to lay her eggs in the best location for survival of her offspring. 10