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Table 1 - Classification of angle closure glaucoma according to Ritch. The four anatomic sites where aqueous flow obstruction may occur Table 2 – Ultrasound Biomicroscopy (UBM) features of filtering blebs according to Yamamoto. Filtering blebs with low internal tissue reflectivity showed the best intraocular pressure control immediately followed by blebs with high tissue reflectivity. Table 3 - Characteristics of the filtering blebs according to Labbé et al. based on Anterior Segment OCT (AS-OCT) imaging and correlation with in vivo confocal microscopy. Diffuse and cystic blebs showed the best intraocular pressure control. Table 4 – Comparison of clinical advantages and disadvantages of Ultrasound Bio-Microscopy (UBM) and Anterior Segment OCT (AS-OCT). Table 1 Site of aqueous humor obstruction Angle closure glaucoma Iris Primary Pupil Block Ciliary Body Plateau Iris Lens Phacomorphic Glaucoma Suprachoroidal Fluid Uveal Effusion/ Malignant Glaucoma Table 2 UBM Low reflectivity High reflectivity Encapsulated Flat Internal reflectivity Reducedmoderate High High High Subscleral route Visible Usually visible Visible Absent Cystic spaces with fluid Possible Possible Cavernous Absent Height Moderatehigh Variable Variable Flattened Table 3 AS-OCT Diffuse Cystic Encapsulated Flattened Suprascleral Low Low High High Internal Low Cystic Absent High reflectivity Heterogeneous spaces Height Variable Variable High Flattened Loose Dense/fibrous reflectivity In vivo Loose connective connective Dense/fibrous confocal connective tissue and tissue over connective microscopy tissue fluid-filled large gap tissue gaps space Table 4 UBM and AS-OCT UBM Performance Advantages -Both technologies -Provides high-resolution -Provides high- provide evidence of cross section images of resolution cross contributing anterior segment and ACA sectional images of mechanisms and including structures behind anterior segment to principal structures the iris such as the ciliary the iris-lens causing angle-closure body, zonule, pars plana, diaphragm glaucoma to decide best anterior lens face, lens -It is easy to operate effective treatment equator and anterior -Does not require -Characterize vitreous much collaboration quantitatively anterior -Enables visualization of -Offers fast acquisition segment using morphology and topography -Allows exact measurement changes of ACA structures knowledge of image parameters as valuable associated with lighting location screening, diagnostic conditions, drugs, -Can be used in early and treatment diagnostic indentation and post-operative period assessment tools age and ocular trauma -Illustrate how the ciliary AS- OCT Disadvantages body/iris complex – anterior chamber angle -Requires immersion -Does not provide amplitude changes with technique, although a saline much detail of age, accommodative filled eye cap can be structures posterior to UBM and AS-OCT UBM AS- OCT and light stimuli adapted to the probe; the iris -Assess glaucoma -May cause filtering surgery Discomfort outcomes Abrasion and infection Potential anterior segment deformation Inadvertent indentation -It is time-consuming -Requires Trained operator Classically a more supine position Collaborative patient