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DIGITAL MEDICINE TO PREDICT THE UNKNOW INHERENT DESIGN OF TECHNOLOGY AND PROCEDURES EXPERIENCES FROM DEVELOPING A «HEART PUMP». Gunnar W. Birkeland (64, UiS) • Past; • Now; FMC BioPolymer Polytec (CEO) • Styremedlem – Helse Fonna • Styreleder – MET Centre (40) ANVENDT FYSIKK OG MATEMATIKK. Oceanografi og Metereologi. Prosess og transport av gasser, olje og vann. Termodynamikk Metallurgi og overflatekjemi. Data analyse, tids serie analyse, statistikk, mva, numerisk modellering (simulering). Besluttningsstøtte, Operasjonell risikoanalyse og teknisk sikkerhet. New tools for decision support has created > 5 000 000 000 NOK last 10 yrs. Ongoing; 2 PhD Flow modeling (pipelines) 1 PhD Flow in porous media 1 PhD Seabed temp modeling Digital medicine To predict the unknown Inherent design of technology and procedures • Required competence; – DOMENE – PHYSICS / MATH – SIMULATION Getty images ANSYS in Healthcare Problem There was no way to predict the results of surgery on children born with a heart defect since the surgery required is different for each individual. Solution Using systems engineering and fluid flow simulation, researchers created a multidomain model of the cardiovascular system that can be used to predict blood flow. Result • The systems model allowed the team to more accurately predict the results of surgery for children with congenital heart defects. • This method can be used to train surgeons by helping them to determine the results of surgery and other treatments on their patients. Because there is a wide spectrum of possible surgical treatments to repair a complex heart defect, patient-specific multidomain modeling can help considerably in choosing the best treatment to ensure optimal blood flow for the patient, ultimately improving quality of life.” Politecnico di Milan ANSYS in Healthcare Academic Research Problem During surgical repair of aneurysms in blood vessels, a stiff guidewire is used to insert a stent graft. The guidewire causes the artery to straighten and deform. Surgeons must estimate the amount of deformation that may occur to ensure optimal placement of the stent graft. Solution University of Rennes researchers fed CT-scan data into ANSYS DesignModeler to create a linear elastic model of arteries. They then used ANSYS Mechanical to accurately simulate the expected arterial deformation. Result Simulations produced more accurate models of arterial deformation than experienced surgeons’ predictions. Simulation gives doctors the luxury of knowing what we will experience during surgery while the patient is still at home so that we are better prepared for surgical treatment. Dr. Jean-Philippe Verhoye Full Professor and Surgeon University of Rennes ANSYS in Healthcare Research Problem Aortic coarctation is a birth defect that involves narrowing of the aorta. This narrowing impairs blood flow from the heart and increases turbulent kinetic energy (TKE) in the blood vessel. Surgeons can use MRI to assess the patient’s existing flow field and TKE, but can’t predict what the results will be following potential interventions. Solution Researchers at Linköping University in Sweden used ANSYS CFX to simulate the turbulent blood flow through the aortic coarctation. Result CFD plots of TKE clearly show flow details that cannot be seen using MRI, which could be valuable to surgeons. ANSYS CFD can predict the outcome of an intervention prior to its being performed; this has generated great interest among clinicians. Lantz ,J. Et al. Numerical and Experimental Assessment of Turbulent Kinetic Energy in an Aortic Coarctation. 2013, Journal of Biomechanics, V46, pp 1851-1858. Linkoping University Polytec is assisting the development of a new heartpump by simulation, design and experimental R&D. Evolutionary Computation • Artificial inteligence by evolutionary algorithms. WWW.POLYTEC.NO