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TREMATODES Helminthes In general:  They are flat worms  Provided with suckers as organs of attachment  Usually as leaf shape  Commonly known as Flukes  No body cavity  Male and Female systems Schistosomes as an exception. are together with 1- Liver Fluke (Fasciola):  Adult: with shoulders  Egg: oval in shape and it’s operculated, it’s immature.  Hosts: Man : definitive host, Snail: first intermediate host, Vegetations: second intermediate host.  Habitat: bile duct.  Infective stage: Encysted Metacercaria.  Complication: bile duct obstruction (Jaundice). Diagnosis:  High eosinophilia  Stool examination: egg in stool  Serology  CT scan or Ultrasound. We have to differentiate between true fascioliasis and false fascioliasis    The two conditions release eggs of Fasciola. False Fasciola: results from eating infected liver of animals as Fasciola may affect sheep, buffalo. In this condition, the patient release eggs in the stool, but without infection with fasciola. To differentiate between true and false Fasciola: we forbid the patient from eating animal liver for three days, then we repeat stool examination. If eggs disappear, it is false fascioliasis, but if eggs still present in the stool, it is true fascioliasis. 2- Fasiolopsis buski (Intestinal Fluke):  Adult without shoulders.  Habitat: small intestine.  Egg: oval in shape with small operculum, immature.  Infective stage: Encysted Metacercaria  Hosts: Man: Definitive host, Snail: first Intermediate host, Chest nut: second intermediate host.  Complication: may lead to intestinal obstruction in the case of presence of large number of worms. Diagnosis:  Stool Examination: egg in stool  Serology 3- Paragonimus (Lung Fluke): Adult: oval in shape with 2 suckers.  Egg: small, oval, operculated, immature.  Infective stage: Encysted Metacercaria  Hosts: Man: Definitive host, Snail: first intermediate host, Crap fish: second intermediate host.  Can lead to Pneumonia and lung abscesses.  Diagnosis:   Sputum Examination. Stool examination in some cases (specially in children) when swallowed. 4- Schistosoma (Blood Fluke):        Have 3 species can be easily differentiated by their egg shape. Adult: differs from other trematodes in being separate sex. Eggs for all species are mature. A- Haematobium: Habitat: blood vessels around the UB. Egg: Yellowish, mature with terminal spine. Diagnosed by Urine examination.  B- Mansoni:  Habitat: Inferior vein of large intestine  Egg: large, yellowish with lateral spine  Diagnosed by : stool examination.  C- Japonicum:  Habitat: Superior veins in small intestine  Egg: small, rounded with small lateral spine.  Diagnosed by: stool examination. Mansoni Japonicum S. Japonicum is the most dangerous species:   It is serious. Starts by katayama fever which is manifested by fever, hepatosplenomegaly and lymphadenopathy. Severe complications are in the form of cerebral and spinal cord affection leading to epilepsy and hemiplegia.