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Cell Processes Mitosis and Meiosis Cell Cycle • The cell cycle is a regular sequence of growth and division that cells undergo. Stage 1: Interphase • Cells grow to its full size • Make an exact copy of its DNA – DNA is found in chromatin • Centrioles are also copied • Prepare to divide into two cells Stage 2: Mitosis • Division of cytoplasm into two new (daughter) cells • Mitosis is divided into 4 parts –Prophase –Metaphase –Anaphase –Telophase The Cell Cycle Prophase– chromatin condense to form chromosomes. – Pairs of centrioles move to opposite side of the nucleus. – Spindle fibers form a bridge between the ends of the cell. – The nuclear envelope breaks down. The Cell Cycle Metaphase–Chromosomes line up across the center of the cell. –Chromosome attaches to a spindle fiber at its centromere The Cell Cycle Anaphase – Centromeres split. – The two chromatids separate and each chromatid becomes a new chromosome. – The new chromosome move to opposite ends. – The cell stretches out as the opposite ends are pushed apart. The Cell Cycle Telophase – Chromosomes begin to stretch out and lose their rod-like appearance. – A new nuclear envelope forms around each region of the chromosomes Stage 3- Cytokinesis – The cytoplasm divides and the organelles are distributed into each of the two cells. The Cell Cycle DNA • DNA has four kinds of nitrogen bases: – A (adenine) – T (thymine) – G (guanine) – C (cytosine) Only A and T pair Only G and C pair The Replication Process • DNA replication begins when the two sides of the DNA molecule unwind and separate, like a zipper unzipping. • Next, nitrogen bases that are floating in the nucleus pair up with the bases on each half of the DNA molecule. • Once the new bases are attached, a new DNA molecule had formed.