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Chapter 38 Care of the Patient with a Neurological Disorder Christensen Kockrow, White, Broyles 5th ed Leslie Lehmkuhl, RN 2009 1 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 1 Key Terms • • • • Agnosia: inability to recognize familiar objects or persons. Can be partial or total Aneurysm: dilation of the wall of a blood vessel usually caused by artheriosclerosis and HTN Aphasia: absence or impairment of the ability to communicate through speech, writing, or signs because of a brain dysfunction (damage to the cerebral cortex) Apraxia: inability to perform purposeful acts or to use objects properly. • Ataxia: Defective muscular coordination (e.g. balance) • Aura: sensation (e.g. light touch) precedes migraine or epileptic sz. • Bradykinesia: extreme slowness of movement • Diplopia: double vision • Dysarthria: Difficulty articulating speech • Dysphagia: severe swallowing difficulty Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 2 Key Terms • Flaccid: weak soft and flabby. Lacking normal muscle tone. • Nystagmus: involuntary movements of the eye (back and forth or cyclical) • Glasgow Coma Scale: Assessment of impaired consciousness (eye, motor and verbal) • Paresis: partial or incomplete paralysis • Global Cognitive Dysfunction : generalized impairment of cognitive function (e.g. intellect, awareness, judgment) Postictal Period: rest period that occurs after sz • Proprioception: spatial positioning (e.g. muscle, posture, position, weight) • Hemianopia: defective vision in ½ of the visual field • • Spastic: involuntary, sudden movement (spasm like) or muscular contraction Hemiplegia: unilateral paralysis • Unilateral Neglect: perceptually unaware of an inattentive to one side of the body • • Hyperreflexia: increased reflex action Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 3 Structural divisions Central nervous system (CNS) • Brain and spinal cord (body’s control center) Peripheral nervous system (PNS) • Somatic nervous system – Sends messages from the CNS to the skeletal muscles; voluntary • Autonomic nervous system – Sends messages from the CNS to the smooth muscle, cardiac muscle and certain glands; involuntary *note: a & i are vowels Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 4 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 5 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 6 Overview of Anatomy and Physiology • Cells of the nervous system – Neuron (fundamental unit of the nervous system) Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 7 CELLS OF THE NERVOUS SYSTEM • Neurons – Consist of three main parts—dendrites; cell body of neuron; and axon • Dendrites conduct impulses to cell body of neuron • Axons conduct impulses away from cell body of neuron Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – Neurons classified according to function • Sensory (afferent) neurons: conduct impulses to the spinal cord and brain • Motor (efferent) neurons: conduct impulses away from brain and spinal cord to muscles and glands • Interneurons: conduct impulses from sensory neurons to motor neurons Slide 8 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 9 (A, C, from Thibodeau, G.A., Patton, K.T. [2003]. Anatomy and physiology. [5th ed.]. St. Louis: Mosby. B, Courtesy of Brenda Russell, PhD, University of Illinois at Chicago.) A, Diagram of a typical neuron. B, Scanning electron micrograph of a neuron. C, Myelinated axon. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 10 Myelin and nerve structure Myelin is the layer that forms around nerves. Its purpose Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 11 Cells of the Nervous System – Neuromuscular junction – Neurotransmitters – Neuron coverings • Myelin sheath • Schwann Cell (PNS only) • Acetylcholine; norepinephrine; dopamine; serotonin Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 12 (A, C, from Thibodeau, G.A., Patton, K.T. [2003]. Anatomy and physiology. [5th ed.]. St. Louis: Mosby. B, Courtesy of Brenda Russell, PhD, University of Illinois at Chicago.) A, Diagram of a typical neuron. B, Scanning electron micrograph of a neuron. C, Myelinated axon. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 13 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 14 Central Nervous System Brain: • Cerebrum interprets sensory messages (e.g. pain, light touch, pressure). Plays a vital role in temp regulation, fluid balance, appetite and some emotions. Influences the HR & hormone secretions • Brainstem carries all nerve fibers between the spinal cord and the cerebrum. Contains the midbrain and pons, aka bridge that connects midbrain and medulla Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. • Cerebellum is responsible for coordination of voluntary muscles, maintenance of balance, equilibrium, and muscle tone. • Spinal cord conducts impulses to and from the brain, serves as a center for reflex action Slide 15 Brain Stem/Cranial Nerves • Brain stem (base of the brain) contains: – Midbrain (CN III-IV) – pons (CN V-VIII) – medulla oblongata (CN IX-XII) – coverings of the brain and spinal cord; ventricles Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 16 Spinal Cord • Spinal cord (17 to 18 inches long) is a 2 way conductor pathway between the brain and peripheral nervous system. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 17 Brain Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 18 Figure 14-2 (From Thibodeau, G.A., Patton, K.T. [1987]. Anatomy and physiology. St. Louis: Mosby.) Sagittal section of the brain (note position of midbrain). Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 19 Figure 14-3 (From Thibodeau, G. A., Patton, K. T. [1990]. Anthony’s textbook of anatomy and physiology. [13th ed.]. St. Louis: Mosby.) Neural pathway involved in the patellar reflex. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 20 Peripheral Nervous System – Spinal nerves (31) – Cranial nerves (12)- all CN transport impulses between the head, neck and brain except the Vagus nerve which serves organs in the thoracic and abd cavities. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – Autonomic nervous system • Sympathetic nervous system “flight or fight” (face threat or run from threat) • Parasympathetic nervous system “vegetative activities” (e.g. digestion, defecation, urination) Slide 21 Effects of Normal Aging on the Nervous System – Loss of brain weight (1% per year p 50 y/o) – Loss of neurons (substantial loss p 50 y/o) – Reduction in cerebral blood flow Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – Decrease in brain metabolism and oxygen utilization – Decreased blood supply to spinal cord causes decreased reflexes Slide 22 Aged Nervous Tissue Aged nervous tissue Aged nervous tissue is less able to rapidly communicate Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 23 Prevention of neurological problems – Avoid drug and alcohol use – Safe use of motor vehicles – Safe swimming practices – Safe handling and storage of firearms Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – Use of hardhats in dangerous construction areas – Use of protective padding as needed for sports – Cigarette smoking decreases lung cancer which frequently will metabolize to the brain Slide 24 Assessment of the Neurological System • History of patients subjective C/O (do not use leading questions) • Mental status • Level of consciousness • Language and speech (sensory, motor, global aphasia) • Cranial nerve function • Motor function • Sensory and perceptual status – Glasgow coma scale *note a decreased LOC is the earliest sign of increases ICP Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 25 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 26 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 27 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 28 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 29 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 30 Laboratory, Diagnostic & Nursing Considerations • Blood and urine – Culture, r/o infection – Drug screens-ingested – Arterial blood gases Guillain-barre • Cerebrospinal fluidcontents see table 14-3 • Computed tomography (CT)check for allergies to seafood and iodine • MRI scan- no metal • PET scan-Alz, tumor, Park. Non -invasive • Lumbar puncture- lay flat the first 8 hrs p obtaining CSF sample. Assess for leakage, give analgesic/ice for HA Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 31 Intracerebellar Hemorrhage - CT Scan Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 32 MRI MRI of the brain Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 33 Lumbar Puncture (spinal tap) Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 34 Figure 14-5 (From Elkin, M.K., Perry, A.G., Potter, P.A. [2004]. Nursing interventions and clinical skills. [3rd ed.]. St. Louis: Mosby.) Position and angle of the needle when lumbar puncture is performed. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 35 Laboratory and Diagnostic Examinations • Electroencephalogram • Electromyogram (EMG)(EEG)- clean hair muscle contraction measurement in • Myelogram- lay flat for 4 response to electrical hrs+check for allergies stimulus. No special prep • Angiogram-allergies • Echoencephalogram-U/S • Carotid duplex- non to view intracranial invasive. U/s and doppler structures, no spec prep technology combined used for TIA’s Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 36 Headaches – Etiology/pathophysiology • Skull and brain tissues are not able to feel sensory pain • Vascular headaches – Migraine – Hypertensive • Tension headaches • Traction-inflammation headaches Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – Clinical manifestations/assessment • Head pain • Prescience of sinus drainage • Migraine headaches – Prodromal (early sign/symptom) » Visual field defects, unusual smells (aura) or sounds, disorientation, paresthesias – During headache » Nausea, vomiting, light sensitivity, chilliness, fatigue, irritability, diaphoresis, edema Slide 37 Headaches (cont) – Medical management/nursing interventions • Diet: limit MSG, vinegar, chocolate, yogurt, alcohol, fermented or marinated foods, ripened cheese, cured sandwich meat, caffeine, and pork • Psychotherapy to help identify areas of stress • Medications – Migraine headaches » Aspirin, acetaminophen, ibuprofen » Ergotamine tartrate (constricts cerebral blood vessels thus reducing cerebral blood flow. Cause a decrease in inflammation and may reduce pain transmission) » Codeine; Inderal Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 38 Headache Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 39 Headaches (continued) – Medical management/nursing interventions • Tension headaches – Non-narcotic analgesics • Cluster headaches • Comfort measures – Cold packs to forehead or base of skull – Pressure to temporal arteries – Dark room; limit auditory stimulation – Narcotics during attacks Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 40 Headache Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 41 Tension-type headache Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 42 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 43 Subdural hematoma ICP – Etiology/pathophysiology • Increase in any content of the cranium • Space-occupying lesions, cerebrospinal problems, cerebral edema • Usually effects one side of the brain which eventually effects both sides -DX • Usually ICP is an emergency situation lending little time for diagnostic tests (CT or MR scan is sometimes used) • Note: Lumbar puncture is not used D/T extraction of CSF can cause pressure changes and poss. lead to brain hemorrhage Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 44 ICP Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 45 Increased Intracranial Pressure – S/S • Diplopia (double vision) • Headache • Changes in level of consciousness is the earliest sign • Monitor Glasgow Coma Scale and be ready to intervene, contact MD and use measures to decreases ICP.. • Pupillary signs change on the same side as the lesion and later may become dilated and fixed. • Widening pulse pressure • Bradycardia • Respiratory problems (lumbar puncture is not used d/t poss brain stem hernia ion) cheynestokes. • High, uncontrolled temperatures • Positive Babinski’s reflex (great toe extends and outer toes fan out) • Seizures • Posturing • Vomiting • Singultus (hiccup) • Blown pupil (fixed and dilated) unilateral eventually Bilateral Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 46 Intracranial Pressure • Pupillary changes Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 47 Increased Intracranial Pressure (continued) – Treatment • Treat cause if possible • Mechanical decompression – Craniotomy (bone flap removed and later replaced) – Craniectomy (bone flap removed and not replaced) • Internal monitoring devices • Elevate HOB 30-45 degrees to promote venous return • Place neck in neutral position (non-flexed or extended) to promote venous return • No nasal suctioning for head injuries D/T possible CSF leakage.. • Corticosteroids (Decadron) reduces cerebral edema.. • Osmotic diuretics (Mannitol) reduce fluid in brain tissue.. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 48 ICP Monitoring Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 49 Common Disorders of the Neurological System • Disturbances in muscle tone and motor function – Etiology/pathophysiology • Damage to the nervous system causes serious problems in mobility – Clinical manifestations/assessment • Flaccid or hyperreflexic muscle tone • Clumsiness or incoordination • Abnormal gait Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 50 Common Disorders of the Neurological System • Disturbances in muscle tone and motor function (continued) – Medical management/nursing interventions • • • • • • • Muscle relaxants Protect from falls Assess skin integrity Positioning Sit up and tuck chin when eating Encourage patient to assist with ADLs Emotional support Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 51 Epilepsy or Seizures – Etiology/pathophysiology • Transitory disturbance in consciousness or in motor, sensory, or autonomic function due to sudden, excessive, and disorderly discharges in the neurons of the brain; results in sudden, violent, involuntary contraction of a group of muscles Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. • Status epilepticus is when recurrent generalized seizures occur at such frequency that full consciousness is not regained between seizures • Generalized seizures are tonic clonic (grand mal)or absence(petit mal) • Partial Seizures are psychomotor (temporal lobe) Jacksonian or myoclonic Slide 52 Grand Mal Seizure Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 53 Epilepsy or seizures (continued) – Clinical manifestations/assessment • Aura (grand mal, psychomotor, Jacksonian-focal) • Postictal period (grand mal, psychomotor, Jacksonian-focal) – Treatment/interventions • During seizure: protect from aspiration and injury (turn on side to maintain airway) • Note onset and duration • Remove all items which can cause injury Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. • Lower to floor if standing • Pad side rails • Anticonvulsant medications (valium common for tonic-clonic), Dilantin, Tegretol • If benzodiazepines are used… monitor for vertigo, dizziness, oversedation. The elderly most likely experience SE’s. Depressed and suicidal clients should be monitored closely (Broyles) Slide 54 Treatment of Epilepsy Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 55 Epilepsy or seizures (continued) – Medical management/nursing interventions (continued) • • • • Adequate rest Good nutrition Avoid alcohol Pharm. methods are primary means of controlling sz activity.. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. • Avoid driving, operating machinery, and swimming until seizures are controlled • Good oral hygiene (gingivitis Dailantin) • Medical alert tag Slide 56 HERNIATED INTERVERTEBRAL DISK • Major cause of chronic back pain. • The intervertebral disk is cartilage cushion between vertebrae bodies • When the herniate or rupture pressure on SC or SN cause symptoms • Symptoms include pain, motor changes, sensory changes, and alterations in reflexes. • Treatment includes bed rest,, stress reduction and immobility of the spine, physical therapy, pain relief, and surgery. • Positioning for comfort is lying on back with knees flexed and a small pillow under head, or lying on unaffected side with affected knee flexed.. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 57 Degenerative Diseases • • • • • • Multiple sclerosis Parkinson’s Alzheimer’s Myasthenia Gravis Amyotrophic Lateral Sclerosis Huntington’s Disease Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 58 Multiple Sclerosis (MS) • Etiology/Patho • Degenerative neurological disorder with demyelination of nerve sheath disrupting neural transmission. • The occurance of sclerotic (hardend) patches replaces myelin and disorupt conduction of impulses. • Onset 20-50 y/o • Affects women more than men Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – S/S • Visual problemsdiplopia, scotomata (spots before the eyes), nystagmus (involuntary eye movement) • Urinary incontinence • Fatigue • Weakness • Incoordination (ataxia) • Sexual problems (impotence in men) • Swallowing difficulties Slide 59 Multiple sclerosis (continued) – Treatments • No specific treatment • Adrenocorticotropic hormone (ACTH), steroids, Valium, Betaseron (interferon beta-1b), Avonex (interferon beta-1a), Pro-banthine; urecholine, Bactrim, Septra, and Macrodantin • Condition may be exacerbated by insomnia, infection, illness, stress, pregnancy, trauma or fatigue.. • Encourage pt to remain active (avoid fatigue) with frequent rest periods Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 60 Multiple sclerosis Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 61 Figure 14-13 (From Lewis, S.M., Heitkemper, M.M., Dirksen, S.R. [2004]. Medical-surgical nursing: assessment and management of clinical problems. [6th ed.]. St. Louis: Mosby.) Pathogenesis of multiple sclerosis. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 62 Nerve supply to the pelvis (MS) Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 63 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 64 Parkinson’s Disease – Etiology/patho • Deficiency of dopamine • Effects the area of the brain that controls movement – S/S • Muscular tremors; bradykinesia (beginning stages , only mild tremor, handwriting changes, a slight limp, or decreased arm swing may be evident, slow speech) • Rigidity; propulsive gait, fall risk • Emotional instability • Heat intolerance • Decreased blinking • “Pill-rolling” motions of fingers Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. • Dysphagia (teach to tuck chin and sit upright when eating and thickened liquids) • Do not rush pts with treatments, meals or PO meds (Broyles) • Rise slowly from bed or chair for pts on levadopa to prevent falls.. Slide 65 Parkinsons – Treatment (cont) • Medications – Levodopa – Sinemet is a combo drug carbidopa/levadopa . The carbidopa prevents levadopa breakdown in peripheral circulation. Thereby, requiring less levadopa (Broyles) – Artane – Cogentin – Symmetrol Surgery – Pallidotomy is not a treatment. However, it interupts transmission impulses that cause tremors. • Therapeutic (Rx) effectiveness can be determined by the patients ability to ambulate, speak, and provide self care (Broyles) Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 66 Parkinson’s (Cont) Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 67 Substantia nigra and Parkinson's disease Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 68 Figure 14-14 (From Lewis, S.M., Heitkemper, M.M., Dirksen, S.R. [2004]. Medical-surgical nursing: assessment and management of clinical problems. [6th ed.]. St. Louis: Mosby.) Nigrostriatal disorders produce parkinsonism. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 69 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 70 Alzheimer’s Disease • Alzheimer’s disease – Etiology/pathophysiology • Impaired intellectual functioning • Degeneration of the cells of the brain • The cells most affected are the neurons that use the neurotransmitter acytecholine • Both brain size and acytecholine decrease • Definitive diagnosis is determined on autopsy that shows an increased aluminum in the brain biopsy.. – S/S • Early stage (do reality orientation) – Mild memory lapses; decreased attention span • Second stage – Obvious memory lapses • Third stage – Total disorientation to person, place, and time – Apraxia; wandering • Terminal stage (validation therapy) – Severe mental and physical deterioration Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 71 Alzheimer’s disease (cont) – Treatment: • Medications – Agitation: lorazepam; Haldol – Dementia: Cognex; Aricept – Nutrition » Finger foods; frequent feedings; encourage fluids: folic acid, Vit B12 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. • Safety – Remove burner controls at night – Double-lock all doors and windows – Constant supervision Slide 72 Myasthenia gravis – Etiology/pathophysiology • Acetylcholine deficiency @ the neuromuscular junction where impulses fail to pass which causes muscular weakness. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. 0 – S/S • Ptosis (drooping of eyelid); diplopia (double vision) • Skeletal weakness; ataxia • Dysarthria; dysphagia • Bowel and bladder incontinence – DX • Tensolin Test • Ptosis Slide 73 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 74 MG (tensilon test) Muscle fatigue Holding your arms above your shoulders until they drop is one Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 75 Myasthenia gravis (continued) 0 – Treatment • Anticholinesterase drugs – Prostigmin – Mestinon • Corticosteroids • May require mechanical ventilation Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 76 Amyotrophic lateral sclerosis (ALS) Lou Gehrig’s disease 0 – Etiology/patho • Progressive fatal disease caused by degeneration of motor neurons in the brain stem and spinal cord gradually degenerate • Electrical and chemical messages originating in the brain do not reach the muscles to activate them • Unknown etiology possibly d/t viral immune response or hereditary defect • Dx made 40-70 yo • Men affected more than women Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – S/S • Weakness of the upper extremities end stages become totally dependent on nurse) • Dysarthria; dysphagia • Muscle wasting • Compromised respiratory function – Treatment/interventions • No cure • Rilutec (Riluzole) • Multidisciplinary ALS teams; emotional support • Nx Dx Self Care Deficit R/T? Slide 77 ALS Muscle Wasting Muscular atrophy Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 78 Huntington’s Disease – Etiology/pathophys • Overactivity of the dopamine pathways • Chronic, progressive heredity disease.. – S/S • Abnormal and excessive involuntary movements (chorea).. • Ataxia to immobility • Deterioration in mental functions (dementia).. – Treatment • No cure; palliative treatment • Antipsychotics • Antidepressants • Antichoreas • Safe environment • Emotional support • High-calorie diet • Genetic counseling.. – Dx fam hx,,s/s,,Dna Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 79 GILLES DE LA TOURETTE’S SYNDROME 2 • Neurological movement disorder that also has prominent behavioral manifestations.. • Symptoms may include motor tics, involuntary repetitive movements of the mouth, face, head, or neck, involuntary swearing, echolalia, or involuntary repetition of person’s own speech.. vocal tics or repetitive involuntary vocalizations that may take the form of sniffing, grunting, throat clearing, or coprolalia (involuntary and inappropriate swearing).. • Treatment includes medications, psychotherapy, family counseling, and a great deal of emotional support. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 80 Vascular Problems • CVA (stroke)- Usually caused by thrombus, embolism, or hemorrhage • TIA’s- intermittent with spontaneous resolution of neurological deficit (unlike strokes) Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 81 Stroke (cerebrovascular accident) – Etiology/pathophysiology • Abnormal condition of the blood vessels of the brain: thrombosis; embolism; hemorrhage • Results in ischemia of the brain tissue • Note- TIA’s are intermittent (tiny clots) reduced blood flow to the brain with self resolution. Temporary interruption in blood flow can result in motor or sensory loss from seconds, minutes or hours (<24 hr) – S/S • • • • • Headache Sensory deficit Hemiparesis; hemiplegia Dysphasia or aphasia Proprioception (unable to discern position of body part w/o looking) • Aphasia (sensory, motor, or global) • Agnosia (total or partial loss ability to recognize familiar objects or people) - Dx • CT scan, MRI, LP (may show blood which is not normal) & PET scan Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 82 Figure 14-16 HOB Flat HOB flat HOB elevated to decrease cerebral perfusion (From Lewis, S.M., Heitkemper, M.M., Dirksen, S.R. [2004]. Medical-surgical nursing: assessment and management of clinical problems. [6th ed.]. St. Louis: Mosby.) Three types of stroke. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 83 Transient Ischemic Attack (TIA) Transient Ischemic attack (TIA) Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 84 Stroke (cerebrovascular accident) (continued) – Treatment • Thrombosis or embolism – Thrombolytics – Heparin and Coumadin • Decadron • Neurological checks • Feeding tube, or teach chin tuck and swallow • Physical, occupational, and/or speech therapy • Plan care with aphasia by first determining the type. Then, adapt communication accordingly • Teach safety to pt and family members • If hemioptic approach from unaffected side • Teach pt to scan area affected and check and/or prevent injury • Stroke preventionteach to check B/P annually, No smoking, check cholesterol level, reduce Na+ and fat in diet.. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 85 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 86 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 87 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 88 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 89 Cranial and Peripheral Nerve Disorders • Trigeminal Neuralgia • Bells Palsy • Infection and Inflammation • Guillian- Barre’ Syndrome • Meningitis • Encephalitis • West Nile Virus • • • • Brain Abscess AIDS Intracranial Tumors Craniocerebral Trauma • Spinal Cord Trauma Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 90 Trigeminal Neuralgia 0 – Etiology/pathophys • Degeneration of or pressure on the trigeminal nerve; tic douloureux • CN V • Neuroligia (nerve pain) follows three branches mandibular, maxuillary and ophthalmic • Remission and exaserbations – S/S • Excruciating, burning facial pain Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – Medical management/nursing interventions • Tegretol • Surgical resection of the trigeminal nerve • Avoid stimulation of face on affected side (e.g. drafts, shaving, solid food, washing face) Slide 91 Bell’s Palsy (peripheral facial paralysis) 0 – Etiology/pathophysiology • Inflammatory process involving the facial nerve VII • No known cause however herpes simplex has been involved – S/S • Facial numbness or stiffness • Drawing sensation of the face • Unilateral weakness of facial muscles • Reduction of saliva Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. • Pain behind the ear • Ringing in ear or other hearing loss – Treatment • • • • Electrical stimulation Moist heat Steroids Massage of the affected area • Facial exercises Slide 92 Facial drooping Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 93 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 94 Guillain-Barré Syndrome (Polyneuritis) – Etiology/pathophys • Inflammation and demyelination of the peripheral nervous system • Possibly viral or autoimmune reaction • Antibodies attack the schwann cells causing breakdown of myelin sheath • Interrupts nerve conduction Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – S/S • Symptoms are progressive • Paralysis usually starts in the lower extremities and moves upward; may stop at any point.. • Respiratory failure if intercostal muscles are affected • May have difficulty swallowing, breathing (monitor closely), and speaking Slide 95 Guillain-Barré Syndrome (Polyneuritis) – Treatment • Adrenocortical steroids • Apheresis (blood is withdrawn, 1 or more components are removed, then re-infused into the donor) • Mechanical ventilation • Gastrostomy tube • Meticulous skin care • Range-of-motion exercises Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 96 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 97 Meningitis – Etiology/pathophysiology • Acute infection of the meninges caused by inflammation • Bacterial or aseptic or viral • Dx lumbar puncture to test CSF for causative agent.. – S/S • Headache; stiff neck (nucchal rigidy) • Irritability; restlessness • Malaise • Nausea and vomiting • Delirium • Elevated temperature, pulse, and respirations Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. • Kernig’s (inability to extend legs without pain) and Brudzinski’s signs – Treatment/ interventions • Antibiotics – Massive doses – Multiple types (Pcn.ampicillin) – IV or intrathecal (2wks followed by Po atb) • Steroids • Anticonvulsants • Dark, quiet room w/ minim,al clt activity.. • Hib prevention (respiratory isolation) Slide 98 Meninges of the spine Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 99 Haemophilus influenza organism This is a gram stain of spinal fluid from a person Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 100 Kernig's sign of meningitis Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 101 Brudzinski's sign of meningitis Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 102 Intracranial tumors – Etiology/pathophysiology • Benign or malignant • Primary (neoplasms) or metastatic (named where tumor appears) • May affect any area of the brain – S/S • Headache • Hearing loss • Motor weakness (unable to perform ADL’s) • Ataxia • Decreased alertness and consciousness • Abnormal pupil response Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – Treatment/ interventions • Surgical removal of tumor – Craniotomy (skull bone removed, tumor extracted, bone replaced) – Intracranial endoscopy (newer method) • Radiation • Chemotherapy • Combination of above Slide 103 Trauma • Craniocerebral Trauma • Spinal Cord Trauma Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 104 Craniocerebral Trauma – Etiology/patho • Motor vehicle and motorcycle accidents, falls, industrial accidents, assaults, and sports trauma • Direct trauma: head is directly injured • Indirect trauma: tension strains and shearing forces • Open head injuries • Closed head injuries • Hematomas (swelling, containing blood) Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – S/S • • • • • • • • HA/Nausea/Vomiting Abnormal sensations Loss of consciousness Bleeding from ears or nose (CSF + Glu) Abnormal pupil size and\or reaction Battle’s sign (fig. 14-21) Decorticate: flexion of arms, wrists and fingers w/ adduction BUE, extension, internal rotation and plantar flexion Decebrate: all 4 extremities in rigid extension, hyperpronation of forearms and plantar flexion Slide 105 Craniocerebral Trauma (continued) – Treatment/interventions • Maintain airway • Monitor for signs of ICP • Teach- no coughing, sneezing, blowing nose or cleaning area. Allow to wipe nose or ears gently • Monitor ears, nose for blood or serous drainage (CSF + glu) • Oxygen • Mannitol and dexamethasone • Analgesics • Anticonvulsants • Note: craniocerebral trauma S/S may not occur until several days p trauma • Remember ABC’s in priority care Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 106 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 107 Concussion Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 108 Head injury Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 109 Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 110 Spinal cord trauma Trauma – Etiology/pathophysiolo gy • Automobile, motorcycle, diving, surfing, other athletic accidents, and gunshot wounds • Fracture of vertebra • Complete cord injury • Incomplete cord injury Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. – S/S • Loss of muscle function depends on level of injury • Spinal shock • Autonomic dysreflexia (injury T6 or above, usually caused by a distended bladder or fecal impaction) reflux CV response causing bradycardia, diaphoresis, severe HA, nasal stuffiness. • Sexual dysfunction Slide 111 Figure 14-22 (From Lewis, S.M., Heitkemper, M.M., Dirksen, S.R. [2004]. Medical-surgical nursing: assessment and management of clinical problems. [6th ed.]. St. Louis: Mosby.) Mechanisms of spinal injury. Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 112 Spinal cord injury Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 113 Spinal Cord Trauma (continued) – Treatment/ interventions • Realignment of bony column for fractures or dislocations: immobilization; skeletal traction – Surgery for spinal decompression • Methylprednisolone • Mobility: slowly increase sitting up • Urinary function: Foley catheter; bladder training – Intermittent catheterization • Bowel program • Any injury involving C1-C7 may require mechanical ventilation Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 114 Nursing Process • Nursing diagnoses – Autonomic dysreflexia – Communication, impaired – Coping, compromised family – Disuse syndrome, risk for – Grieving – Infection, risk for – Knowledge, deficient – Memory, impaired Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 115 Nursing Process • Nursing diagnoses (continued) – Mobility, impaired physical – Nutrition, imbalanced: less than body requirements – Pain, acute, chronic – Self-care deficit – Swallowing, impaired – Thought process, disturbed – Tissue perfusion (cerebral), ineffective Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 116 Glasgow Coma Scale Eyes open Spontaneously (4) To speech (3) To pain (2) None (1) Best verbal response Orientated (5) Confused (4) Inappropriate words (3) Incomprehensible sounds (2) None (1) Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Best motor response* Obeys commands (6) Localizes pain (5) Withdraws to pain (4) Flexion (abnormal) to pain (3) Extension to pain (2) none(1) Slide 117 Brain Tumor Mosby items and derived items © 2006, 2003, 1999, 1995, 1991 by Mosby, Inc. Slide 118