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TW ANPS 020 Fiekers 01-14-13 HUM ANAT AND PHYS Page 1 Blackboard We will use Mastering A&P In BB, you will find the course ID. If you had ANPS 019 last semester, you don't need a new code. If you have registering classes information, contact me. Otherwise, contact Dr. Black. She will be your contact person for the class. You will have five professors this semester. They will cover various topics in the course. We are using the same textbook as last semester. You will use it more this semester. We have a new course manual with the presentation Power Points slides. Each presentation will be uploaded to BB. Make sure that you check BB for announcements, the syllabus, course schedule, etc. Each announcement is sent by email, as well. Make sure that you check your UVM email. That is your responsibility. Exams The first three exams are on Mondays. Exam 1 Exam 2 Exam 3 Final TBD Feb 4 March 18 April 8 Each exam will correspond to each colored block in BB. They are not cumulative. The exams are usually one week after we finish a block. The four exams are mandatory! If you need to reschedule an exam, see Ellen Black immediately. You cannot reschedule the day before the exam. You must let her know ASAP. There are about 400 students in this course. It is difficult to schedule the finals due to the class size. We will announce final information on BB. TW ANPS 020 Fiekers 01-14-13 HUM ANAT AND PHYS Page 2 Attendance in the course is not mandatory, but it is highly recommended. Grading 80% of your final grade comes from the four exams. Each exam is worth 20%. 20% of your final grade is from the lab. You must do the laboratory assignments and exams. All of the lecturers will be happy to help you. It is very important that you have your questions answered for the course. Ask any questions. Supplemental Instructor Jillian Arnie Leikauskas She is great. She will be here on Wednesday to introduce herself and get feedback for the best meeting times. ELLEN BLACK, PH. D. INTRODUCTION TO ANPS AND THE CARDIOVASCULAR SYSTEM Given Courtyard North 206 656-9397 [email protected] We will review a little today. For those of you who have had 019, you have seen all of this. We will talk about blood vessels by the end of the week. You will need to know the vocabulary to understand the course. Cells have unique functions. An organ's function is determined by the properties of the cells within it. Cells are usually grouped with similar cells into tissues Organs are generally built with tissue layers. TW ANPS 020 Fiekers 01-14-13 HUM ANAT AND PHYS Page 3 FOUR TYPES OF TISSUES 1. 2. 3. 4. Epithelial Connective Muscle Nervous Chapter 4 is a review of the cells and tissue type arrangement in the body. EPITHELIAL TISSUE Grouped into glands – cells packed together They make stuff Two glands EXOCRINE GLANDS – Glands that secrete stuff into passage ways ENDOCRINE GLANDS – Produces a material put into extracellular space where it is packed up by the blood stream and carried away All cells in the body have access to it, but they may not respond to it. There are no glands associated with the cardiovascular system. Sheets of cells – EPITHELIA Individual epithelial cells when packed into sheets are in different shapes Cuboidal, columnar, squamous Single layer – EPITHELIUM Double layer 40 cells thick Any layer more than one layer is stratified epithelia CONNECTIVE TISSUE Biggest class of cells General connective tissue proper Cartilage and bone - structural connective tissues There are some organs that have those tissues in them TW ANPS 020 Fiekers 01-14-13 HUM ANAT AND PHYS Page 4 BLOOD Fibroblasts that make fibers and the filler in-between Most important Loose – aeolar - cells and loose collagen fibers and fluid in-between Densely packed - irregular - make tons of connective tissue fibers, mostly collagen MUSCLE TISSUE – SKELETAL: Smooth or cardiac Skeletal muscle at the beginning and end of the GI tract. Mostly, we will see smooth muscle which is in most of the organs of the body. Tiny cells that are packed into a network of smooth muscle. After we finish cardiac muscle, we will not mention it, again. NERVOUS TISSUE On the slide, each red band is a single skeletal muscle cell. The neuron releases chemicals onto the cells and tells them to contract. We will tell you about an organ. We may not mention where the nervous tissue is because it is within the layers of the cells. Organs are built in layers This is a cross-section of an esophagus (round with blue, purple, and grey) There are different stains or dyes to show the organization and layers. In the white spaces, the food will go through there. White spaces are holes. They are white because there is nothing there to hold the dye. The darker purple lines are spaces of epithelium. It is between 10 – 20 cells thick which means that it is stratified. These types of cells are subject to wear and tear. They are stratified squamous epithelium. The grey is the connective tissues. They are attached to the muscular layer which is smooth muscle and organized. TW ANPS 020 Fiekers 01-14-13 HUM ANAT AND PHYS Page 5 Outside, there is a layer of grey, connective tissue, again. AUTONOMIC NERVOUS SYSTEM OR ANS The ANS is responsible for controlling the nervous system which controls your organs for you. The ANS is controlled by the CNS. The ANS is an outgoing or EFFERENT system to the organs. The brain needs feedback to assist in keeping track of what the organs are doing at any point in time. This semester, we will talk about VISCERA which means organs. The viscera collects sensory information and sends that information to the CNS TWO PARTS OF THE ANS Parasympathetic Sympathetic The ANS involuntary targets cells. Every organ has smooth muscle cells, cardiac muscle cells or gland cells. PARASYMPATHETIC The Craniosacral system CRANIUM is the vault that holds the brain. The craniosacral system goes from the brainstem to the spinal cord. The rest and digest system. Storage of energy reserves Slowing of the heart rate Emptying the bladder and bowels – housekeeping function Narrowing pupils and airways – protection function TW ANPS 020 Fiekers 01-14-13 HUM ANAT AND PHYS Page 6 ANATOMY OF THE ANS: THE PARASYMPATHETIC SYSTEM You need two neurons to get to the cells where you want something done. Neuron 1 – solid line It comes out of the cranium Neuron 2 – dotted line Comes out of the spinal cord Cranial Nerve 10: Vagus Nerve The nerve talks to almost everything. It is the workhorse for the parasympathetic system. The parasympathetic nervous system does not go to the limbs. The system works on the organs. THE SYMPATHETIC SYSTEM Thoracolumbar system Releases energy reserves Speeds up heart rate Increases blood pressure, shunting flow to organs until escape Increases air to lungs Dilates pupils to aid in escape Originates in the spinal cord and goes into the sympathetic chain The sympathetic system goes everywhere: organs, limbs, and skin On the slide, it appears as though one side speaks to the organs while the other side communicates with the skin. That is only for illustration! Most organs have dual innervation The organs are controlled by the sympathetic and parasympathetic which means DUAL INNERVATION CHEMISTRY OF THE ANS The Red is the Sympathetic Nervous System while the Blue is the Parasympathetic Nervous System TW ANPS 020 Fiekers 01-14-13 HUM ANAT AND PHYS Page 7 In the sympathetic, Neuron 1 Neuron 2 emits Acetylcholine onto Neuron 2 produces a nicotine-type receptor If you smoke, the nicotine from the cigarettes can turn on neurons without the brain wanting them turned on. Then, norepinephrine is released which is close to epinephrine. It will bind with target cells to turn them on. Epinephrine is the first line emergency drug. It will turn on any cell in the SNS. In the parasympathetic, Neuron 1 Neuron 2 emits Acetylcholine onto Neuron 2 produces a muscarinic choline receptor