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Curriculum Vitae Arturo Eduardo Gonzalez-Iglesias April 03, 2013 General Information University address: Biomathematics Department of Mathematics College of Arts and Sciences 1017 Academic Way, 208 Love Building Florida State University Tallahassee, Florida 32306-4510 Phone: 850-644-5420; Fax: 850-644-9807 E-mail address: [email protected] Web site: http://www.neuro.fsu.edu/associate_faculty/iglesiasa/ Professional Preparation 2001 Ph.D., University of Buenos Aires, Argentina. Major: Biological Sciences. Postdegree Education and Training 2001–2006 POSTDOCTORAL TRAINING IN BIOCHEMISTRY AND PHYSIOLOGY. Professional Experience 2008–present Assistant Scholar/Scientist, Biomathematics, Florida State University. 2006–2008 Postdoctoral Associate, Biological Science, Florida State University. Language Proficiency Spanish - native in speaking, reading, and writing. Fellowship(s) Postdoctoral Research Associate (2006–2008). Visiting Fellow (2001–2006). Vita for Arturo Eduardo Gonzalez-Iglesias Postdoctoral Fellow (2001–2002). Research Fellow (1996–2001). Honors, Awards, and Prizes ENDOCRINE SOCIETY TRAVEL GRANT AWARD, Endocrine Society (2003). ($500). PRIZE ACCESIT "Dr. Bernardo A. Houssay, 2000, Argentine Society of Biology (2000). ($1,000). Current Membership in Professional Organizations American Society for Pharmacology and Experimental Therapeutics Endocrine Society Society for Neuroscience Teaching 1- Colloquium speaker for the two week-long Summer Program in Science, Technology, Engineering, and Mathematics, Dept of Mathematics, Florida State University (Tallahassee, FL), July 26-August 7, 2009 2Teacher Assistant (1999-2001), Biotechnology and Molecular Biology area, Biological Sciences Department, University of Buenos Aires (FCEyN-UBA). 3- Assistant of the Master in Biochemical Endocrinology, Faculty of Pharmacology and Biochemistry, University of Buenos Aires (UBA). Subject: "Hormones and its signal transduction pathways through G-protein coupled receptors and receptor tyrosine kinases." 2001. 4- Assistant of the post-graduate course "Physiology of Reproduction" held at the Instituto de Biología y Medicina Experimental (IByME-FCEyN- UBA). Subject: "Radioimmuneassay (RIA)". 1995, 1997, 1999. 5- Assistant of the Master in Biochemical Endocrinology, Faculty of Pharmacology and Biochemistry, University of Buenos Aires (UBA). Subject: "Insulin and Growth Factors". 1997, 1999. 6Assistant of the course "Radioimmuneassay- RIA II IByME" held at the Instituto de Biología y Medicina Experimental (IByME-FCEyN- UBA). Course director: Dr. Eduardo H. Charreau. (This course gives a certificate issued by the National Nuclear Regulator Organism (ARN) that allow the usage of radioactive material at research and clinical labs). Amount of practical hours: 120. 1998-1999. 7- Invited speaker at the course "Updates in Signal Transduction" of the Argentine Society of Biology (SAB) held at the Instituto de Biología y Medicina Experimental (IByME). Course director: Dr. Omar P. Pignataro. Lecture: "Ca2+ and calcium channels". Lab: "Introduction to intracellular Ca2+ determination using a fluorometric method". October 1999. 8- Teacher Assistant ad-honorem of the graduate course "Introduction to Molecular and Cellular Biology", Biotechnology and Molecular Biology area, Biological Sciences Department, UNIVERSITY OF BUENOS AIRES (FCEyN- UBA). Course director: Dr. A.R. Kornblihtt. March-July 1999. 9- Invited speaker at the post-graduate course "Updates in Signal Transduction" of the Argentine Society of Biology (SAB) held at the Instituto de Biología y Medicina Experimental (IByME). Director: Dr. Omar P. Pignataro. Lecture: "Ca2+ and calcium channels". September-october 1998. 10- Assistant ad-honorem of the graduate course "Introduction to Molecular Physiology", Biotechnology and Molecular Biology area, Biological Sciences Department, UNIVERSITY OF BUENOS AIRES (FCEyN- UBA). Course director: Dr. Daniel J. Goldstein. August-Dec 1995. Courses Taught Summer Program in Science, Technology, Engineering, and Mathematics Biotechnology and Molecular Biology (at University of Buenos Aires) Page 2 Vita for Arturo Eduardo Gonzalez-Iglesias Master in Biochemical Endocrinology (at University of Buenos Aires) Updates in Signal Transduction (at Insittute of Biology and Experimental Medicine, Buenos Aires, Argentina) Introduction to Molecular and Cellular Biology (at University of Buenos Aires) Physiology of Reproduction Radioimmunoassay- RIA II IByME (at Institute of Biology and Experimental Medicine, Buenos Aires, Argentina) Introduction to Molecular Physiology (at University of Buenos Aires) Doctoral Committee Member Stathopoulos, A. M., doctoral candidate. Research and Original Creative Work Program of Research and/or Focus of Original Creative Work Our research aims to understand how the hypothalamic oxytocin-dopaminergic (and other neuropeptidergic) systems interact to control the secretion of prolactin from the anterior pituitary gland in different physiological states relevant to reproduction in females (estrous cycle, pseudopregnancy, pregnancy and lactation). A second program of research focuses on novel roles of oxytocin in the regulation of anterior pituitary hormones other than prolactin. Publications Refereed Journal Articles Kretschmannova, K., Kucka, M., Gonzalez-Iglesias, A. E., & Stojilkovic, S. S. (2012). The expression and role of hyperpolarization-activated and cyclic nucleotide-gated channels in endocrine anterior pituitary cells. Molecular Endocrinology, 26(1), 153-164. Helena, C. V., Cristancho-Gordo, R., Gonzalez-Iglesias, A. E., Tabak, J., Bertram, R., & Freeman, M. E. (2011). Systemic oxytocin induces a prolactin secretory rhythm via the pelvic nerve in ovariectomized rats. American Journal of Physiology (Regul Integr Comp Physiol), 301(3), R676-R681. Sirzen-Zelenskaya, A., Gonzalez-Iglesias, A. E., de Monvel, J. B., Bertram, R., Freeman, M. E., Gerber, U., & Egli, M. (2011). Prolactin induces a hyperpolarizing current in rat paraventricular oxytocinergic neurons. Journal of Neuroendocrinology, 23(10), 883-893. Tabak, J., Tomaiuolo, M., Gonzalez-Iglesias, A. E., Milescu, L. S., & Bertram, R. (2011). Fast-Activating Voltage- and Calcium-Dependent Potassium (BK) Conductance Page 3 Vita for Arturo Eduardo Gonzalez-Iglesias Promotes Bursting in Pituitary Cells: A Dynamic Clamp Study. Journal of Neuroscience, 31(46), 16855-168563. Bertram, R., Helena, C., Gonzalez-Iglesias, A. E., Tabak, J., & Freeman, M. E. (2010). A Tale of Two Rhythms: The Emerging Roles of Oxytocin in Rhythmic Prolactin Release. Journal of Neuroendocrinology, 22(7), 778-784. Popovic, M. A., Stojilkovic, S. S., & Gonzalez-Iglesias, A. E. (2010). Effects of isoquinolonesulfonamides on action potential secretion coupling in pituitary cells. Horm Mol Biol Clin Invest, 1(1), 35-42. Tabak, J., Gonzalez-Iglesias, A. E., Toporikova, N., Bertram, R., & Freeman, M. E. (2010). Variations in the Response of Pituitary Lactotrophs to Oxytocin during the Rat Estrous Cycle. Endocrinology, 151(4), 1806-1813. Tomaiuolo, M., Bertram, R., Gonzalez-Iglesias, A. E., & Tabak, J. (2010). Investigating heterogeneity of intracellular calcium dynamics in anterior pituitary lactotrophs using a combined modelling/experimental approach. Journal of Neuroendocrinology, 22(12), 1279-1289. Zemkova, H., Kucka, M., Li, S., Gonzalez-Iglesias, A. E., Tomic, M., & Stojilkovic, S. S. (2010). Characterization of purinergic P2X4 receptor channels expressed in anterior pituitary cells. American Journal of Physiology (Endocrinology and Metabolism), 298(3), E644-E651. Stojilkovic, S. S., Murano, T., Gonzalez-Iglesias, A. E., Andric, S. A., Popovic, M. A., Van Goor, F., & Tomic, M. (2009). Multiple Roles of Gi/o Protein-Coupled Receptors in Control of Action Potential Secretion Coupling in Pituitary Lactotrophs. Annals of the New York Academy of Sciences, 1152, 174-186. Gonzalez-Iglesias, A. E., Murano, T., Li, S., Tomic, M., & Stojilkovic, S. S. (2008). Dopamine inhibits basal Prolactin release in pituitary lactotrophs through Pertussis Toxin-sensitive and –insensitive signaling pathways. Endocrinology, 149(4), 1470-1479. Gonzalez-Iglesias, A. E., Jiang, Y., Tomic, M., Kretschmannova, K., Andric, S. A., Zemkova, H., & Stojilkovic, S. S. (2006). Dependence of electrical activity and Ca2+ influx-controlled prolactin release on adenylyl cyclase signaling pathway in pituitary lactotrophs. Molecular Endocrinology, 20(9), 2231-2246. Gonzalez-Iglesias, A. E., Kretschmannova, K., Tomic, M., & Stojilkovic, S. S. (2006). ZD7288 inhibits exocytosis in an HCN-independent manner and downstream of voltage-gated Ca2+ influx in pituitary lactotrophs. Biochemical and Biophysical Research Communications, 346(3), 845-850. Page 4 Vita for Arturo Eduardo Gonzalez-Iglesias Kretschmannova, K., Gonzalez-Iglesias, A. E., Tomic, M., & Stojilkovic, S. S. (2006). Dependence of HCN channel activity on basal cAMP production in spontaneously firing GH3 cells. Journal of Neuroendocrinology, 18(7), 484-493. Andric, S. A., Zivadinovic, D., Gonzalez-Iglesias, A. E., Lachowicz, A., Tomic, M., & Stojilkovic, S. S. (2005). Endothelin-induced, Long Lasting, and Ca2+ Influx-independent Blockade of Intrinsic Secretion in Pituitary Cells by Gz Subunits. Journal of Biological Chemistry, 280(29), 26896-26903. He, M. L., Gonzalez-Iglesias, A. E., Tomic, M., & Stojilkovic, S. S. (2005). Release and extracellular metabolism of ATP by ecto-nucleotidase eNTPDase 1-3 in hypothalamic and pituitary cells. Purinergic Signalling, 1(2), 135-144. Suarez, C., Diaz-Torga, G., Gonzalez-Iglesias, A. E., Cristina, C., & Becu-Villalobos, D. (2004). Upregulation of Angiotensin II type 2-receptor expression in estrogen-induced pituitary hyperplasia. American Journal of Physiology (Endocrinology and Metabolism), 286(5), E786-E794. Andric, S. A., Gonzalez-Iglesias, A., van Goor, F., Tomic, M., & Stojilkovic, S. S. (2003). Nitric oxide inhibits Prolactin secretion in pituitary cells downstream of Voltage-gated Calcium influx. Endocrinology, 144(7), 2912-2921. He, M. L., Gonzalez-Iglesias, A. E., & Stojilkovic, S. S. (2003). Role of nucleotide P2 receptors in calcium signaling and prolactin release in pituitary lactotrophs. Journal of Biological Chemistry, 278(47), 46270-46277. Suarez, C., Diaz-Torga, G., Gonzalez-Iglesias, A. E., Vela, J., Mladovan, A., Baldi, A., & Becu-Villalobos, D. (2003). Angiotensin II phosphorylation of extracellular signal-regulated kinases in rat anterior pituitary cells. American Journal of Physiology (Endocrinology and Metabolism), 285(3), E645-E653. Suarez, C., Tornadu, I. G., Cristina, C., Vela, J., Gonzalez-Iglesias, A. E., Libertun, C., Diaz-Torga, G., & Becu-Villalobos, D. (2002). Angiotensin II and calcium signaling in the pituitary and hypothalamus. Cellular and Molecular Neurobiology, 22(3), 315-333. Diaz-Torga, G. S., Mejia, M. E., Gonzalez-Iglesias, A. E., Formia, N., Becu-Villalobos, D., & Lacau-Mengido, I. M. (2001). Metabolic cues for puberty onset in free grazing Holstein heifers naturally infected with nematodes. Theriogenology, 56(1), 111-122. Gonzalez-Iglesias, A., Suarez, C., Feierstein, C., Diaz-Torga, G. S., & Becu-Villalobos, D. (2001). Desensitization of Angiotensin II effect on [Ca2+]i, inositol triphosphate and prolactin in pituitary cells. American Journal of Physiology (Endocrinology and Metabolism), 280(3), E462-E470. Page 5 Vita for Arturo Eduardo Gonzalez-Iglesias Gonzalez-Iglesias, A., Diaz-Torga, G., Piroli, G., Achaval-Zaia, R., De Nicola, A. F., Libertun, C., & Becu-Villalobos, D. (2000). Bromocriptine restores Angiotensin II response in pituitary hiperplasia. Molecular and Cellular Endocrinology, 165(2), 67-74. Lacau-Mengido, I. M., Mejia, M., Diaz-Torga, G. S., Gonzalez-Iglesias, A., Formia, N., Libertun, C., & Becu-Villalobos, D. (2000). Endocrine studies in ivermectin-treated heifers from birth to puberty. Journal of Animal Science, 78, 1-8. Gonzalez-Iglesias, A., Diaz-Torga, G., Lux-Lantos, V., Libertun, C., & Becu-Villalobos, D. (1999). Calcium influx and intracellular stores in angiotensin II stimulation of normal and hyperplastic pituitary cells. American Journal of Physiology (Endocrinology and Metabolism), 277, E455-E463. Mejia, M., Gonzalez-Iglesias, A., Diaz-Torga, G. S., Villafane, P., Formia, N., Libertun, C., Becu-Villalobos, D., & Lacau-Mengido, I. M. (1999). Effects of continuous ivermectin treatment from birth to puberty on growth and reproduction in dairy heifers. Journal of Animal Science, 77(6), 1329-1334. Diaz-Torga, G., Gonzalez-Iglesias, A., Achaval-Zaia, R., Libertun, C., & Becu-Villalobos, D. (1998). Angiotensin II induced intracellular calcium mobilization and prolactin release are altered in adenohypophyseal cells from tumor bearing rats. American Journal of Physiology (Endocrinology and metabolism), 274, E534-E540. Duvilanski, B. H., Velardez, M. O., Gonzalez-Iglesias, A., Theas, S., Seilicovich, A., & Becu-Villalobos, D. (1998). Nitric oxide donors modify intracellular calcium levels in rat anterior pituitary cells. Molecular and Cellular Endocrinology, 146, 19-26. Lacau-Mengido, I. M., Gonzalez-Iglesias, A., Diaz-Torga, G., Thyssen-Cano, S., Libertun, C., & Becu-Villalobos, D. (1998). Effect of stage of development and sex on gonadotropin-releasing hormone secretion in in vitro hypothalamic perifusion. Proceedings of the society for Experimental Biology and Medicine, 217, 445-449. Lacau-Mengido, I. M., Gonzalez-Iglesias, A., Lux-Lantos, V., Libertun, C., & Becu-Villalobos, D. (1998). Ontogenic and Sexual Differences in Pituitary GnRH Receptors and Intracellular Ca2+ Mobilization Induced by GnRH. Endocrine, 8, 177-183. Becu-Villalobos, D., Gonzalez-Iglesias, A., Diaz-Torga, G., & Libertun, C. (1997). Brain sexual differentiation and gonadotropins secretion in the rat. Cellular and Molecular Neurobiology, 17, 699-715. Rey-Roldan, E. B., Lux-Lantos, V. A. R., Gonzalez-Iglesias, A. E., Becu-Villalobos, D., & Libertun, C. (1996). Baclofen, a Gamma-amino butyric acid B agonist, modifies hormonal secretion in pituitary cells from infantile females rats. Life Sciences, 58, 1059-1065. Page 6 Vita for Arturo Eduardo Gonzalez-Iglesias Invited Book Chapters Gonzalez-Iglesias, A. E., & Freeman, M. E. (2012). Brain control over pituitary gland hormones. In Pfaff, D (Ed.), Neuroscience in the 21st Century. Springer, NY. Retrieved from http://www.who.int/hinari/en/ Invited Reviews Suarez, C., Tornadu, I. G., Cristina, C., Vela, J., Gonzalez-Iglesias, A., Libertun, C., Diaz-Torga, G., & Becu-Villalobos, D. (2002). Angiotensin II and calcium signaling in the pituitary and hypothalamus. Cellular and Molecular Neurobiology, 22(3), 315-333. Becu-Villalobos, D., Gonzalez-Iglesias, A., Diaz-Torga, G., & Libertun, C. (1997). Brain sexual differentiation and gonadotropins secretion in the rat. Cellular and Molecular Neurobiology, 17, 699-715. Presentations Refereed Presentations at Conferences Gonzalez-Iglesias, A. E., Cristancho-Gordo, R., Arias-Cristancho, J. A., & Bertram, R. (presented 2012, October). Peripheral administration of oxytocin acutely increases systemic prolactin levels and advances the onset of the prolactin surge in proestrus. Poster presentation at 42nd Annual Meeting of the Society for Neuroscience, Society for Neuroscience, New Orleans, LA. (International) Tabak, J., Gonzalez-Iglesias, A. E., Cristancho-Gordo, R., & Bertram, R. (presented 2012, October). Multiple actions of hypothalamic oxytocin on pituitary cells. Poster presentation at 42nd Annual Meeting of the Society for Neuroscience, Society for Neuroscience, New Orleans, LA. (International) Gonzalez-Iglesias, A. E., Cristancho-Gordo, R., Bertram, R., & Tabak, J. (presented 2011, July). Oxytocin stimulates Calcium signaling and hormone release in rat lactotrophs, somatotrophs and gonadotrophs. Poster presentation at 9th World Congress on Neurohypophysial Hormones, The Physiological Society, Boston, MA. (International) Helena, C. V., Cristancho-Gordo, R., Gonzalez-Iglesias, A. E., Tabak, J., Bertram, R., & Freeman, M. E. (presented 2011, June). Systemic oxytocin induces a prolactin secretory rhythm via the pelvic nerve in ovariectomized rats. Poster presentation at 93rd Anual meeting of the Endocrine Society, Endocrine Society, Boston, MA. (International) Helena, C. V., Cristancho-Gordo, R., Gonzalez-Iglesias, A. E., Tabak, J., Bertram, R., & Freeman, M. E. (presented 2010, November). Oxytocin induces an acute prolactin response that acts in the brain to induce a prolactin secretory rhythm. Poster presentation Page 7 Vita for Arturo Eduardo Gonzalez-Iglesias at 40th Annual Meeting of the Society for Neuroscience, Society for Neuroscience, San Diego, CA. (International) Gonzalez-Iglesias, A. E., Tabak, J., Cristancho-Gordo, R., Bertram, R., & Freeman, M. E. (presented 2010, July). Stimulatory effects of Oxytocin on growth hormone release and calcium signaling in rat anterior pituitary cells. Poster presentation at The 7th International Congress of Neuroendocrinology (ICN 2010), International Neuroendocrine Federation (INF), Rouen, France. (International) Tabak, J., Tomaiuolo, M., Milescu, L., Gonzalez-Iglesias, A. E., Freeman, M. E., & Bertram, R. (presented 2010, July). BK channels promote bursting in pituitary cells. Poster presentation at The 7th International Congress of Neuroendocrinology (ICN 2010), International Neuroendocrine Federation (INF), Rouen, France. (International) Kennett, J. E., Poletini, M. O., Gonzalez-Iglesias, A. E., & Freeman, M. E. (presented 2008, June). Progesterone prevents the decrease in estradiol-induced prolactin secretion caused by oxytocin antagonism. Poster presentation at 90th Annual Meeting of the Endocrine Society, The Endocrine Society, San Francisco, CA. (International) Toporikova, N., Gonzalez-Iglesias, A. E., Tabak, J., Bertram, R., & Freeman, M. E. (presented 2007, November). Calcium and Prolactin responses to oxytocin in pituitary lactotrophs during the estrous cycle. Poster presentation at 37th Annual Meeting of the Society for Neuroscience, Society for Neuroscience, San Diego, CA. (International) Gonzalez-Iglesias, A. E., Jiang, Y., Tomic, M., Kretschmannova, K., Andric, S. A., Zemkova, H., & Stojilkovic, S. S. (presented 2006, February). Dependence of basal prolactin (PRL) release on reciprocal modulation of cyclic nucleotides and voltage-gated calcium influx in spontaneously firing pituitary lactotrophs. Poster presentation at Gordon Research Conference- Prolactin Family, Gordon Research Conferences, Ventura, CA. (International) Kretschmannova, K., Gonzalez-Iglesias, A. E., Tomic, M., Sherman, A., & Stojilkovic, S. S. (presented 2005, February). Expression and role of hyperpolarization-activated channels in rat anterior pituitary cells. Poster presentation at Biophysical Society 49th Annual Meeting, Biophysical Society, Long Beach, CA. (National) Gonzalez-Iglesias, A. E., Tomic, M., Andric, S. A., Zemkova, H., & Stojilkovic, S. S. (presented 2004, October). Interplay between Intracellular Cyclic Nucleotides and Voltage-Gated Calcium Influx in Resting Pituitary Cells. Poster presentation at 34th Annual Meeting of the Society for Neuroscience, Society for Neuroscience, San Diego, CA. (International) Tomic, M., Gonzalez-Iglesias, A. E., Andric, S. A., Zemkova, H., & Stojilkovic, S. S. (presented 2004, August). Dependence of calcium signaling and prolactin release on cyclic nucleotide-controlled pacemaker activity in pituitary lactotrophs. Poster presentation at 12th International Conference on Second Messengers and Phosphoproteins, the Salk Page 8 Vita for Arturo Eduardo Gonzalez-Iglesias Institute, the Scripps Research Institute, and the Burnham Institute, Montreal, Canada. (International) He, M. L., Gonzalez-Iglesias, A. E., & Stojilkovic, S. S. (presented 2004, June). Release and extracellular metabolism of ATP by ecto-ATPase NTPDase1-3 in hypothalamic and pituitary cells. Poster presentation at 4th International Symposium of Nucleosides and Nucleotides (Purines 2004), Italian Purine Club, Chapel Hill, NC. (International) He, M., Gonzalez-Iglesias, A. E., & Stojilkovic, S. S. (presented 2003, November). Identification of purinergic receptors and channels controlling prolactin secretion in pituitary cells. Poster presentation at Annual Meeting of the Society for Neuroscience, Society for Neuroscience, New Orleans, LA. (International) Zemkova, H., He, M., Gonzalez-Iglesias, A. E., & Stojilkovic, S. S. (presented 2003, November). Ectonucleotidases control the pattern of signaling by P2X receptors at nanomolar ATP concentrations. Poster presentation at Annual Meeting of the Society for Neuroscience, Society for Neuroscience, New Orleans, LA. (International) Gonzalez-Iglesias, A. E., He, M., Andric, S. A., Tomic, M., & Stojilkovic, S. S. (presented 2003, June). Dependence of pacemaker activity and basal prolactin release on cyclic nucleotide signaling pathway in rat lactotrophs. Poster presentation at 85th Annual Meeting of the Endocrine Society, The Endocrine Society, Philadelphia, PA. (International) Suarez, C., Gonzalez-Iglesias, A., Mladovan, A., Diaz-Torga, G., Garcia-Tornadu, I., Baldi, A., & Becu-Villalobos, D. (presented 2001, November). Activación de Map-kinasas inducida por angiotensina II (AngII) en células de hipófisis normal e hiperplásica. Poster presentation at XLVI Congreso anual de la Sociedad Argentina de Investigación Clínica, Sociedad Argentina de Investigacion Clinica, Mar del Plata, Provincia de Buenos Aires (Argentina). (National) Diaz-Torga, G., Becu-Villalobos, D., Mejia, M., Gonzalez-Iglesias, A., Formia, N., & Lacau-Mengido, I. M. (presented 2000, December). Leptin levels increase before puberty onset in Holstein heifers. Poster presentation at XXI World Buiatrics Congress, World Association of Buiatrics (WAB), Punta del Este (Uruguay). (International) Diaz-Torga, G., Gonzalez-Iglesias, A. E., Suarez, C., Lacau-Mengido, I. M., & Becu-Villalobos, D. (presented 2000, November). Angiotensin II induced homologous and heterologous desensitization in pituitary cells. Poster presentation at XXXII Reunión Anual de la Asociación Argentina de Farmacología Experimental, Asociación Argentina de Farmacología Experimental, Mendoza, (Argentina). (National) Page 9 Vita for Arturo Eduardo Gonzalez-Iglesias Gonzalez-Iglesias, A., Diaz-Torga, G., Achaval de Zaia, R., & Becu-Villalobos, D. (presented 2000, November). Upregulation of Angiotenin II type 2 (AT2) receptor in estrogen induced pituitary hyperplasia. Poster presentation at XXXII Reunión Anual de la Asociación Argentina de Farmacología Experimental, Asociación Argentina de Farmacología Experimental, Mendoza, (Argentina). (National) Achaval de Zaia, R., Gonzalez-Iglesias, A. E., Diaz-Torga, G., & Becu-Villalobos, D. (presented 1999, November). Hiperplasia hipofisaria por estrógenos: regulación de GH-IGF-I por factores de crecimiento. Poster presentation at XLII Reunión CIentífica de la Sociedad Argentina de Investigación Clínica, Sociedad Argentina de Investigación Clínica, Mar del Plata, Prov. Buenos Aires (Argentina). (National) Lacau-Mengido, I., Gonzalez-Iglesias, A., Diaz-Torga, G., Mejia, M., Formia, N., & Becu-Villalobos, D. (presented 1999, November). Niveles de leptina, GH e IGF-I durante el desarrollo en bovinos en pastoreo. Efectos de un tratamiento crónico con ivermectina en animales naturalmente expuestos a infestación con parásitos gastrointestinales. Poster presentation at XLII Reunión CIentífica de la Sociedad Argentina de Investigacion Clinica, Sociedad Argentina de Investigacion Clinica, Mar del Plata, Prov. Buenos Aires (Argentina). (National) Gonzalez-Iglesias, A., Diaz-Torga, G., Achaval-Zaia, R., Libertun, C., & Becu-Villalobos, D. (presented 1998, November). Efectos de bromocriptina e hidroxiprogesterona sobre una resputesta alterada a Angiotenisna II en prolactinomas inducidos por estrógenos. Poster presentation at XXX Reunión Anual de la Asociación Argentina de Farmacología Experimental, Asociación Argentina de Farmacología Experimental, Corrientes, (Argentina). (National) Gonzalez-Iglesias, A., Diaz-Torga, G., Lux-Lantos, V., Libertun, C., & Becu-Villalobos, D. (presented 1998, November). Participación de los depósitos intracelulares de Ca2+ sensibles a tapsigargina y de los canales dependientes de voltaje (CCDV) en la movilización de Ca2+ inducida por angiotenina II en células hipofiarias normales e hiperplásicas. Presentation at XLIII Reunión Científica de la Sociedad Argentina de Investigacion Clinica, Sociedad Argentina de Investigacion Clinica, Mar del Plata, Prov. of Buenos Aires (Argentina). (National) Suarez, C., Gonzalez-Iglesias, A. E., Feierstein, C., Diaz-Torga, G., & Becu-Villalobos, D. (presented 1998, November). Movilización de Ca2+ intracelular inducida por Angiotensina II: Desensibilización y variaciones a lo largo del ciclo estral. Poster presentation at XXX Reunión Anual de la Asociación Argentina de Farmacología Experimental, Asociación Argentina de Farmacología Experimental, Corrientes, (Argentina). (National) Velardez, M., Gonzalez-Iglesias, A., Theas, S., Seilicovich, A., Becu-Villalobos, D., & Duvilanski, B. H. (presented 1998, November). Efecto del óxido nítrico (N0) sobre la concentración intracelular de Ca++ en células adenohipofisarias de rata. Presentation at XLIII Reunión Científica de la Sociedad Argentina de Investigación Clínica, Sociedad Page 10 Vita for Arturo Eduardo Gonzalez-Iglesias Argentina de Investigación Clínica, Mar del Plata, Prov. of Buenos Aires (Argentina). (National) Gonzalez-Iglesias, A., Diaz-Torga, G. S., Mejia, M., Formia, N., Villafane, P., Tempesti, S., Libertun, C., Villalobos, D., & Lacau-Mengido, I. M. (presented 1997, November). Efecto de la ivermectina sobre la IGF-I serica y la pubertad en terneras Holando en pasturas infectadas con nematodes. Poster presentation at XXIX Reunión Anual de la Asociación Argentina de Farmacología Experimental, Asociación Argentina de Farmacología Experimental, Corrientes (Argentina). (National) Velardez, M. O., Gonzalez-Iglesias, A., Theas, S., Seilicovich, A., Becu-Villalobos, D., & Duvilanski, B. H. (presented 1997, November). El óxido nítrico (NO) disminuye el Ca++ intracelular en células de adenohipófisis. Poster presentation at XLII Reunión Científica de la Sociedad Argentina de Investigación Clínica, Sociedad Argentina de Investigación Clínica, Mar del Plata, Prov. of Buenos Aires (Argentina). (National) Lacau-Mengido, I. M., Mejia, M., Formia, N., Gonzalez-Iglesias, A., Diaz-Torga, G. S., Villafane, P., Tempesti, S., Libertun, C., & Becu-Villalobos, D. (presented 1997, August). Differences in growing rate and IGF-I in ivermectin treated and nematode naturally infected dairy heifers from birth to puberty. Poster presentation at 16th International Conference of the World Association for the Advancement of Veterinary Parasitology, World Association for the Advancement of Veterinary Parasitology, Suncity, (South Africa). (International) Diaz-Torga, G., Achaval de Zaia, R., Gonzalez-Iglesias, A., & Becu-Villalobos, D. (presented 1996, November). Efectos in vitrode EGF, IGF-I y TGF en la proliferación y secreción de células hipofisarias de rata, con o sin estradiol (E2). Poster presentation at XXVIII Reunión Anual de la Asociación Argentina de Farmacología Experimental, Asociación Argentina de Farmacología Experimental, Parana, Prov. of Entre Rios (Argentina). (National) Gonzalez-Iglesias, A., Diaz-Torga, G., Achaval de Zaia, R., Libertun, C., & Becu-Villalobos, D. (presented 1996, November). Angiotensina II (AII): Control de la secreción y proliferación de células hipofisarias normales y tumorales. Poster presentation at XXVIII Reunión Anual de la Asociación Argentina de Farmacología Experimental, Asociación Argentina de Farmacología Experimental, Parana, Prov. of Entre Rios (Argentina). (National) Gonzalez-Iglesias, A., Thyssen-Cano, S. M., Lacau-Mengido, I. M., Diaz-Torga, G., Libertun, C., & Becu-Villalobos, D. (presented 1995, November). Diferencias sexuales en la sensibilidad hipotálamo-gonadotrófica en la rata infantil: Receptores de GnRH y movilización de Ca++ intracelular. Poster presentation at XXVII Reuníón Anual de la Asociación Argentina de Farmacología Experimental, Asociación Argentina de Farmacología Experimental, Buenos Aires, (Argentina). (National) Page 11 Vita for Arturo Eduardo Gonzalez-Iglesias Nonrefereed Presentations at Symposia Stathopoulos, A. M., Helena, C. V., Fletcher, P. A., Gonzalez-Iglesias, A. E., & Bertram, R. (presented 2013, March). Vasoactive Intestinal Peptide Stimulates Prolactin by Inhibiting Dopamine _and Stimulating Oxytocin Neurons. In 2013 Rushton Lecture Series. Poster presentation at the meeting of Program in Neuroscience, Florida State University, Florida State University, Tallahassee, FL. (Local) Arias-Cristancho, J. A., Gonzalez-Iglesias, A. E., & Bertram, R. (presented 2013, February). Immunocytochemical characterization of oxytocin receptors in cultured anterior pituitary cells. In 8th Annual Undergraduate research Poster board competition. Poster presentation at the meeting of Tri-Beta Biological Honor Society, Sigma Tau Chapter, Florida State University, Tallahassee (FL). (Local) Invited Lectures and Readings of Original Work Gonzalez-Iglesias, A. E. (2012, March). Gi/o–dependent pathways controlling Action Potential-Secretion Coupling in Pituitary Lactotrophs". Delivered at Indo-US Science & Technology Forum, Agra (India). (International) Gonzalez-Iglesias, A. E. (2012, March). Tutorial on Anterior Pituitary cells. Delivered at Indo-US Science & Technology Forum, Agra (India). (International) Gonzalez-Iglesias, A. E. (2010, August). Introduction to Neuroendocrinology. Delivered at Mathematical Biosciences Institute, Ohio State University, Columbus (OH). (International) Contracts and Grants Contracts and Grants Funded Bertram, Richard (PI), Tabak-Sznajder, J., & Gonzalez-Iglesias, A. E. (Sep 2012–Aug 2015). Mathematical Analysis of Electrical Oscillations. Funded by National Science Foundation. (1220063). Total award $275,000. Bertram, R., Gonzalez-Iglesias, A. E., & Tabak, J. (Feb 2010–Jan 2015). Regulation of prolactin secretion at the lactotroph. Funded by National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK, NIH). (2R01DK043200). Total award $2,386,601. Page 12 Vita for Arturo Eduardo Gonzalez-Iglesias Service Florida State University FSU University Service Member, Animal Care and Use Committee (2012–2013). The Profession Guest Reviewer for Refereed Journals WIREs Membrane Transport and Signaling (2013–present). The Biophysical Journal (2012–present). Journal of Neuroendocrinology (2011–present). Cellular and Molecular Neurobiology (2010–present). Page 13