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Krok. Microbiology with basis immunology (2 year, Pharmacy)
Опис:
2 курс, модуль 1, фарм. факультет КРОК
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?During microbiological inspection of crude drugs encapsulated bacteria were revealed. What
method was applied for capsule detection?
Burry-Gins
Ziehl-Neelsen
Neisser
Gram
Ozheshko
In order to keep eubiotics viable and stable, frozen microorganisms are dried out under the conditions
of high vacuum. This method is called:
Lyophilization
Pasteurization
Tyndallization
Inactivation
Hybridization
Antibiotics can be classified according to various principles. According to the action mechanism
cephalosporins relate to the following group:
Inhibitors of cell wall synthesis
Inhibitors of protein synthesis
Inhibitors of respiratory processes
Inhibitors of oxidative phosphorilation
Inhibitors of cytoplasmic membrane synthesis
Bacteritic preparations are subdivided into groups according to their purpose and production
principles. What group do the preparations for initiation of active immunity relate to?
Vaccines
Immune sera
Immunoglobulins
Monoclonal antibodies
Bacteriophages
Bacteriological examination for bacteria carrying of drugstore workers revealed that one of the
pharmacists had bacteria of genus Staphylococcus. What morphological pecularities of microbial cell
arrangement are typical for this genus?
They are arranged in form of bunch of grapes
They are arranged in form of a chain
They are arranged separate
They are arranged in pairs
They are arranged in tetrads
Analysis of sputum obtained from a patient with suspected pneumonia revealed gram-positive
diplococci. They were slightly elongated, with the pointed opposite ends. What microorganisms were
revealed in the sputum?
Streptococcus pneumoniae
Staphylococcus aureus
Klebsiella pneumoniae
Neisseria meningitidis
Streptococcus pyogenes
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A pharmacy produced a batch of vials with glucose solution for injections. What is the best way for
their sterilization?
Autoclave sterilization by flowing steam (fractional method)
Autoclave sterilization under 2 atmosphere pressure
Dry-heat sterilization
X-ray exposure
UV exposure
Study of the antibioticogram of the pure salmonella culture revealed multiple antibiotic resistance.
What factor might have caused this effect?
R-plasmids
Chromosomal mutations
F-plasmids
Temperate phages
Transposons
Staphylococci were isolated in pure culture from a patient with sepsis. These were staphylococci
producing betalactamase. Such property should be taken into account when:
Choosing an antibiotic for treatment
Determining biiochemical properties
Determining the strain pathogenicity
Differentiating specific types of staphylococci
Choosing optimal conditions for cultivation
A female patient has been treated with antibiotics for a long time. Thereafter examination of smears
form vaginal secretion revealed oval cells with well-defined nucleus, some cells gemmate. What
preparations can help to confirm the diagnosis "candidosis"?
Antifungal
Antibacterial
Antichlamydial
Antiviral
Antiprotozoal
Bacteria may contain not only chromosomal but also extrachromosomal hereditary elements called
plasmids. Presence of plasmid genes can show itself by:
Multiple drug resistance
Stain resistance
Physical factor resistance
Sporogenesis ability
Mobility
Which of the following sterilization methods ensures total death of microorganisms and their spores
during one-time thermal processing of an object?
Autoclaving
Boiling
Tyndallization
Pasteurization
Filtration
Aetiological factors for the infectious diseases are often microorganisms with various ultrastructure.
Which of the following microorganism groups relates to the eucariots?
Protozoa
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Viruses
Viroids
Prions
Scotobacteria
Antibiotics are classified by sources of production. Name an antibiotic of bacterial origin:
Gramicidin
Penicillin
Tetracycline
Lysozyme
Gentamycin
Production of a number of drugs requires sterile isotonic solution. Choose the optimal method of its
sterilization:
Steam under pressure sterilization
Dry heat sterilization
Boiling
Direct flame sterilization
Pasteurization
A pharmaceutical company received from a laboratory a delivery order of diagnostic medications
used for studying antigenic properties of causative agent. Name these preparations:
Diagnostic sera
Allergens
Diagnosticums
Immunoglobulins
Bacteriophages
When a smear is stained by Burry-Gins method a mucous structure that is tightly bound with the
cellular wall of bacteria and has well-defined outer boundaries can be detected. This element of a
bacteria cell is called:
Capsule
Spore
Filaments
Ribosomes
Episomes
A bacterial cell obtains nutrients by different ways. One of them is the facilitated diffusion that is
realized by special membrane carrier proteins. What are these proteins called?
Permeases
Lyases
Oxidoreductases
Isomerizing enzymes
Ligases
A patient was prescribed with an antitumoral antibiotic that inhibits synthesis of nucleic acids in the
cells. What of the following antibiotics has such a mechanism of action?
Actinomycin
Tetracycline
Nystatin
Lincomycin
Erythromycin
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A drugstore received a supply of a drug that is widely used for treatment of many virus diseases since
it is not virus specific. What drug is it?
Interferon
Remantadin
Metisazone
Immunoglobulin
Vaccine
A patient was administered an antibiotic of animal origin for the corneal ulcer treatment. What is it
called?
Lysozyme
Chlorophyllipt
Nystatin
Imanin
Gramicidin
What method ensures reliable sterilization of biological fluids (sera, solutions, enzymes, vitamines
etc.) that can't stand high temperatures?
Tyndallization
Dry-heat sterilization
Flowing steam
Moist steam under pressure
Flaming
Pathogenic microorganisms are characterized by presence of aggression enzymes that determine their
virulence. Select an aggression enzyme:
Hyaluronidase
Carbohydrase
Transferase
Oxidase
Lyase
Before a surgical operation, a surgeon treated his hands with an alcohol-containing solution. Which
group of drugs does this solution relate to?
Antiseptics
Disinfectants
Sterilizing solutions
Detergents
Surface-active substances
A patient was taken to a hospital with acute food poisoning caused by home-made canned
mushrooms. The product analysis revealed some microorganisms that develop only in the absence of
oxygen. What microorganisms caused the poisoning?
Obligate anaerobes
Facultative anaerobes
Microaerophiles
Obligate aerobes
Capnophiles