Download Psychopharm Study Guide

Psychopharmacology Final Exam Study Guide!
Hi, All!
Here’s the “study guide” I promised. This should help to focus the studying just a bit.
In this guide, I am only giving the questions, not the options (that way, it’s still a learning
experience, not just a recognition test) for 67 potential questions. The actual exam will
have 20 – 35 questions.
I hope this helps, and I wish you the best of luck!
Potential Multiple Choice Questions
1. A _____________ can usually bind to many ____________.
2. A client using a classical antipsychotic is displaying confusion (moreso than
usual), incontinence, pulse irregularities, and a relatively high fever. What’s with
this guy?
3. A decrease in the effectiveness of a drug that is administered repeatedly is
typically called:
4. A dose response curve is:
5. A drug that can pass rapidly and easily through the capillary wall surrounding the
brain must be:
6. A drug that deactivates the enzyme monoamine oxidase (MAO) acts as a(n
7. A drug that impairs the effect of a neurotransmitter at the level of the synapse by
occupying and deactivating a postsynaptic receptor is considered
8. A drug that inhibits acetylcholinesterase would:
9. A drug that is more efficacious than another drug has:
10. A drug that is more potent than another drug has:
11. A substance or a factor that causes the production of physical or developmental
abnormalities in the developing embryo or fetus is called a:
12. Agitation, hypersalivation, incoordination, and hyperthermia are symptoms of
what ADR and is common to which medication?
13. All of the following medications are prescribed for Alzheimer’s except:
14. An ion channel within a postsynaptic receptor responds to binding of a
neurotransmitter by:
15. Anitdepressants should be continued at therapeutic dosage levels for about how
long?
16. During the process of behavioral drug tolerance, after repeated, frequent use of a
drug in the same environment:
17. Exposure to a drug that inhibits the breakdown of a neurotransmitter:
18. Fluoxetine facilitates an increase of 5-HT in the synapse. Enzymes are often “too
busy” breaking down this excess indolamine to adequately metabolize other
neurotransmitters or exogenous substances. This kind of interaction is called:
19. In addition to seizure disorder, anticonvulsant compounds such as carbamazepine
are also used to treat:
20. In general tricyclic antidepressants (TCAs) act as:
21. In it’s simplest form, “pharmacokinetics” describes a drug’s:
22. Lowered heart rate, respiratory arrest, drowsiness, coma, and dependence are all
adverse reactions common to:
23. Most of the products of body metabolism is excreted by the:
24. One substance capable of inhibiting enzymatic degradation in the liver and
gastrointestinal tract is:
25. Placebo effects:
26. Potency refers to:
27. The 3 major categories of adverse drug reactions are
28. The benzodiazepines (such as diazepam):
29. The benzodiazepines are MOST effective in treating:
30. The dose of a drug which will be fatal to half of the population is called:
31. The fact that caffeine cannot exert as much CNS stimulation as amphetamine
indicates that:
32. The main advantage to administering a drug through transdermal patches is:
33. The primary neurotransmitter substance of the central nervous system is:
34. The process by which drugs are absorbed, distributed within the body,
metabolized, and excreted is called:
35. The ratio provided by dividing the dose which is toxic for 50% of the population
by the dose which is therapeutic for 50% of the population is called the:
36. The reduction in the number or sensitivity of receptors in response to prolonged
activation by a drug is termed:
37. The study of how a drug interacts with a receptor is termed:
38. The study of the movement of drugs through the body is termed:
39. The therapeutic index is derived by...
40. The therapeutic index refers to:
41. The time for the plasma level of a drug to fall by 50 percent is termed the:
42. Two types of medications associated with a high risk of serious adverse drug
reactions are:
43. Usually, a minimum of __ to ___ weeks of antidepressants is needed before its
efficacy for that patient can be determined.
44. What are the 3 major drug classes of antidepressants?
45. What is the typical first-line treatment for ADHD?
46. What is unique about Lithium's metabolism in the body?
47. When amphetamine binds to and activates the dopamine receptor on the
postsynaptic membrane, it is considered a(n):
48. Which group of antidepressants has the least problematic ADR profile?
49. Which method of administration has the highest rate of bioavailability?
50. Which neurotransmitter system is MOST affected by classical antypsychotics?
51. Which of the following are clinically relevant effects of a sedative hypnotic?
52. Which of the following are common side-effects of SSRI's?
53. Which of the following best describes bioavailability?
54. Which of the following best describes bioequivalence?
55. Which of the following best describes Lipophilic substances?
56. Which of the following best describes Orthostatic Hypotension?
57. Which of the following describes the most problematic issue with regard to
prescribing opiate analgesics?
58. Which of the following describes the phenomenon that occurs when two or more
drugs are taken together and create a “more-than-additive” effect?
59. Which of the following diseases is sometimes mimicked by antipsychotic
medication?
60. Which of the following have tetragonic effects?
61. Which of the following is NOT an atypical antipsychotic?
62. Which of the following is the common form of drug dosage administration?
63. Which of the following SSRI’s are not FDA approved for treating Depression?
64. Which of the following substances represents the drug class that may be used in
place of opiate analgesics when an opiate cannot be used due to respiratory
problems (e.g., age or injury)?
65. While the exact mechanism of action for barbiturates and benzodiazepines is
unknown, it is believed to primarily use the _________________ system to
decrease brain activity.
66. Your client has been using haloperidol for about a week. Toward the end of that
week, he’s developed a nasty rash, a fever, and aches in the joints. What’s going
on?
67. Your client has been using Paxil for a little over 3 months. For the last month or
so, she’s reported a general stabilization of mood and no longer meets the criteria
for depression. It may be time to: