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Meiosis Terms: Heredity Trait Genetics Fertilization Pure-bred Gene Alleles Dominant allele Recessive Hybrid Phenotype Genotype Homozygous Heterozygous Meiosis Crossing-over Homologous chromosomes Tetrad Diploid Haploid Gamete - Content: 46=magic number: somatic cells all have 46 chromosomes. N=the number of chromosomes from 1 parent. Diploid=2n, two sets of chromosomes Karyotype= a map of chromosomes in the human body. 23= the “sexy” number Gametes= any reproductive cells (sperm and egg cells.) Haploid= half the number of chromosomes in a normal cell. 1n= 23, haploid. All human gametes have 23 chromosomes Meiosis= cell division of reproductive cells only. End goal= 4 haploid daughter cells. Daughter cells are not identical due to crossing-over Crossing-over= allows for genetic diversity. Concepts/Skills: There are two types of phases: meiosis 1 and meiosis 2. Interphase: DNA replicates. Prophase 1: DNA condenses into chromosomes and crossing-over occurs with homologous chromosomes Metaphase 1: Nuclear membrane dissolves, and spindle fibers attach to homologous chromosomes at the centromere when they join to form tetrads. Anaphase 1: Spindle fibers pull the chromosomes toward the centrioles taking 2 sister chromosomes per side. Telophase 1: Nuclear envelope reforms, with 2 sister chromosomes per nucleus. Cytokinesis: Cell membrane pinches in forming 2 daugher cells with non identical homologous chromosomes. Prophase 2: Nuclear envelope breaks down, and new spindle fibers form. Metaphase 2: Spindle fibers attach to both sides of the centromere. Anaphase 2: Spindle fibers pull the sister chromosomes apart. Telophase 2: Nuclear envelope reforms. Cytokinesis: Cell membrane pinches. Chromosomes become chromatin. Diagrams: Mitosis: -No crossingover. - Makes 2 cells. -2 cells are identical. -1 division. -Diploid cells. Both: -DNA replication. -PMAT Sample questions: 1. What are the differences between meiosis and mitosis? 2. What is a karyotype? 3. How many chromosomes are in a somatic cell? 4. What is a gamete? 5. What is the end result of meiosis 2? 6. Why does crossing-over make meiosis different from mitosis? 7. What are the phases of meiosis? 8. How are meiosis and mitosis similar? 9. What are tetrads? 10. How many sets of chromosomes does a diploid cell have? Meiosis: -Haploid cells. - Form tetrads. - 2 divisions. - Crossingover occurs. -Produces 4 cells.