Download Tick-Bite Patch: A First Generation Immunoinformatics Derived Anti

Licensing Opportunity
from the University of Rhode Island
The Tick-Bite Patch: A First generation Immunoinformatics
Derived Anti-Tick Vaccine with Transdermal Delivery
Description of Invention: Almost everyone becomes somewhat alerted when a mosquito bites; that
familiar buzz and painful bite usually trigger immediate SWAT. Ticks, however, are sneak biters. There are
tiny in size, they crawl up under clothes without making a sound, their bites are painless, and at least in the
case of Lyme disease, the pathogen infection rate in ticks (at 20% or more) is exceptionally high. Ticks
transmit more than 20 pathogens, including Category A-C and emerging-re-emerging agents, all capable of
causing significant disease in humans and animals.
Potential Areas of Application:
1) Discovery of a broad-spectrum vaccine against tucks and tick-borne pathogen transmission would
represent a major milestone for improving public health.
Main Advantages of Invention:
1)
This project uses high throughput informatics technologies to indentify candidate T-cell epitope
peptides that can be used as abroad-spectrum anti-tick vaccine.
2) It also combines peptide chemistry research with proprietary transdermal delivery technology;
together these studies will be integrated to create a device for immunizing humans with antigenic tick
salivary molecules.
3)
Lead Inventor:
Thomas Mather et al, CELS-PLS
Status:
US patent application 61/350,559 filed June 2, 2010
Publications (with links):
Category: Biological, Pharmaceutical, Life Sciences
Licensing Status:
Available for licensing
Reference #:10-0602
Please contact David R. Sadowski or Raymond Walsh - Division of Research & Economic Development, University of
Rhode Island, 75 Lower College Rd. Suite 001, Kingston, RI 02881; 401-874-4807 or Fax 401-874-7832
http://www.uri.edu/research/tro/executive/sadowski.html
Rev. 01-14-10