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Cell Division CHAPTER 1: CELL DIVISION MULTIPLE CHOICE QUESTIONS 1. During the ‘gap’ phases of the cell cycle, most of the activity is directed towards A. DNA replication. B. Resting for the next step. C. Sorting the chromosomes. D. Synthesizing cytoplasmic organelles. 2. DNA replication occurs A. between the gap phases of interphase B. immediately before prophase of mitosis C. during prophase of mitosis D. during prophase of meiosis 3. The process of replication in the S phase of the cell cycle is connected with which of the followings? A. Doubling of the number of chromatids. B. Doubling of the DNA content exclusively. C. Doubling of the number of chromosomes. D. Doubling of the amount of energy in mitochondria. 4. A particular cell has half as much DNA as some of the other cells in a mitotically active tissue. The ‘cell’ is most likely in…. A. G1 C. Metaphase B. G2 D. Anaphase 5. At which stages of the mitotic cell cycle do these events occur? A. B. C. D. DNA replication Breakdown of nuclear membrane Division of centromere Interphase Interphase Interphase Prophase Metaphase Prophase Interphase Prophase Metaphase Anaphase Anaphase Anaphase 6. Mitosis involves the following stages. 1 2 3 4 Chromosomes line up on the equatorial plate Nuclear envelope forms and cytoplasmic division begins Chromosomes become visible and spindle forms Sister chromatids move to opposite ends of the cell What are the correct names of these stages? Biology Unit, KMJ 08-09 1 Cell Division A. B. C. D. 1 Prophase Prophase Metaphase Metaphase 2 Anaphase Telophase Anaphase Telophase 3 Metaphase Metaphase Prophase Prophase 4 Telophase Anaphase Telophase Anaphase 7. Figure 1 shows measurements taken during one mitotic cell cycle. Figure 1 Which stage of mitosis occurs during X and which measurements are illustrated by curves 1 and 2? Stage of mitosis commencing at X A. B. C. D. Anaphase Anaphase Metaphase Metaphase Distance between centromeres of chromosomes & poles of spindle Distance between centromeres of sister chromatids 1 2 1 2 2 1 2 1 8. Figure 2 shows the chromosome complement of a cell just before the metaphase stage of mitosis. Figure 2 What will be the chromosome complement at telophase? Biology Unit, KMJ 08-09 2 Cell Division A. B. C. D. 9. If a parent cell has fourteen chromosomes prior to mitosis, how many chromosomes will each daughter cell have? A. Twenty-eight because each chromatid is a chromosome. B. Fourteen because the chromatids separate. C. Only seven after mitosis is finished. D. Any number between seven and twenty-eight. 10. Mitosis and cytoplasmic division function in…. A. Growth, tissue repair, and sometimes asexual reproduction in many multicellular eukaryotes. B. Asexual reproduction of single-celled eukaryotes. C. Gamete formation in prokaryotes. D. Both A and B 11. Figure 3 shows anaphase of mitosis. Figure 3 Which diagram shows anaphase I during meiosis in the same organism? A. B. C. D. 12. Figure 4 shows a cell at anaphase I of meiosis. Figure 4 Biology Unit, KMJ 08-09 3 Cell Division Which diagram shows a normal gamete that could be produced from this cell? A. B. C. D. 13. Figure 5 shows some chromosomes at late prophase of mitosis. Figure 5 How many chromosomes would be present in one nucleus at telophase II of meiosis? A. 6 B. 12 C. 18 D. 24 14. How does the second meiotic division differ from mitosis? In the second meiotic division…. A. Chiasmata form between the chromatids of a bivalent. B. Each chromosome replicates to form two chromatids during metaphase. C. Exchange of genetic material occurs between chromatids. D. The separating chromatids of a pair differ genetically. 15. Which of the following sentences about meiosis are correct? I. Meiosis halves the amount of DNA. II. Meiosis enables sexual reproduction. III. Meiosis results in the genetic diversity of offspring. IV. The first meiotic division in eukaryotes is similar to mitosis. V. Meiosis in higher eukaryotes occurs in somatic cells and gametes. A. B. C. D. I, II and IV I, II and III II, III and V II, III and IV Biology Unit, KMJ 08-09 4 Cell Division STRUCTURED QUESTIONS 1. Figure 6 below shows 4 stages of mitosis in animal cell. Figure 6 a) Name the structures A : __________________ C : ____________________ B : __________________ D : ____________________ [4 marks] b) i. Name the stages of division shown by cells 1 and 3. Cell 1: __________________ Cell 3: __________________ [2 marks] ii. Using the number given to each cell above, arrange the stages as they occur in the mitotic sequence. ____________________________________________________________ [1 mark] c) If one organism has 92 chromatids in a somatic cell, how many chromosomes are there during: i. metaphase in meiosis I : ____________________ ii. metaphase in mitosis : ____________________ iii. metaphase in meiosis II : ____________________ [3 marks] Biology Unit, KMJ 08-09 5 Cell Division 2. a) Review the steps of mitosis. i. At which step do the chromosomes separate? ____________________________________________________________ ii. When does the chromatin condense into chromosomes? ____________________________________________________________ iii. Why must mitosis be preceded by replication of the chromosomes? ____________________________________________________________ [3 marks] b) Figure 7 represents the amount of DNA present per cell during several nuclear divisions. 4n 2n Z n W X Y Time Figure 7 i. Which type of nuclear division is represented by the diagram? ____________________________________________________________ [1 mark] ii. State TWO reasons why the process in (i) is necessary. ____________________________________________________________ ____________________________________________________________ [2 marks] iii. What phases are represented by the dashed lines W, X, and Y? W : ____________________ X : ____________________ Y : ____________________ [3 marks] Biology Unit, KMJ 08-09 6 Cell Division iv. What type of cells is represented by the line Z? ____________________________________________________________ [1 mark] 3. a) i. Draw diagrams of metaphase I and anaphase for the cell shown below. Figure 8 Metaphase I Anaphase [4 marks] ii. Describe the events that occur in the cell immediately before metaphase I. ____________________________________________________________ ____________________________________________________________ [2 marks] iii. Suggest why it is important that the chromatids remain attached at the centromere until anaphase? ____________________________________________________________ ____________________________________________________________ [2 marks] Biology Unit, KMJ 08-09 7 Cell Division b) i. How does the amount of DNA in a nucleus differ between the start and the end of interphase? ____________________________________________________________ [1 mark] ii. There are 46 chromosomes in a human body cell. How many DNA molecules are there in a cell nucleus at the start of prophase? ____________________________________________________________ [1 mark] ESSAY QUESTIONS 1. a) With the help of labelled drawings, describe the behavior of chromosomes in a cell that contains a chromosome number of 2n=4 in each of the followings:i. Metaphase of mitosis, metaphase I and metaphase II. ii. Anaphase of mitosis, anaphase I and anaphase II. State the number of chromosomes and chromatids for each cell after completing cytokinesis. [12 marks] b) How do animal and plant cells differ in the way they divide through mitosis? [4 marks] c) State the significance of mitosis. [4 marks] 2. a) With the aid of labelled drawings, describe meiosis I [8 marks] b) List the significant differences between mitotic and meiotic cell divisions. [12 marks] Biology Unit, KMJ 08-09 8