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GEORGIA BAPTIST COLLEGE OF NURSING
OF MERCER UNIVERSITY
NUR 312 Pharmacology in Nursing
Unit IV: Drugs That Affect Fluid-Gas Transport:
Oxygenation
Lesson Objectives: At the completion of this lesson, the student will:
1.
Relate drug therapy to the physiology and pathophysiology of
oxygenation.
2.
Outline the pharmacodynamics and pharmacokinetics of specific
agents that affect oxygenation.
3.
Outline the side effects associated with a specific classification of drugs.
4.
Relate specific drugs to their drug class.
5.
Discuss the rationale for giving specific drugs and their effects on health.
6.
Utilize the nursing process to identify specific nursing considerations
related to drugs that affect oxygenation.
Content Outline:
1.
Review of respiratory physiology and pathophysiology
2.
Antitussives and Expectorants: Dynamics/Kinetics, Therapeutics,
Side Effects/Adverse Reactions, and Nursing Considerations
2.1. Narcotic Antitussives
2.1.1. Codeine
2.1.2. Hydrocodone
2.2
Non-narcotic Antitussives
2.2.1. Benzonatate (Tessalon)
2.2.2. Diphenhydramine (Benadryl)
2.3. Expectorants/mucolytics
2.3.1. Acetylcysteine (Mucomyst)
2.3.2. Dornase Alpha (Pulmozyme)
2.3.3. Guaifenesin
3.
Bronchodilators: Dynamics/Kinetics, Therapeutics,
Side Effects/Adverse Reactions, and Nursing Considerations
3.1
Xanthine derivatives
3.1.1. Aminophyllin (Somophyllin)
3.1.2. Theophylline (Slophyllin, Theodur)
3.2 Sympathomimetic agent
3.2.1. Albuterol (Proventil)
3.2.2. Terbutaline (Brethene
3.3
Anticholinergics- Ipratropium (Atrovent)
4.
Other agents: Dynamics/Kinetics, Therapeutics, Side Effects/Adverse
Reactions, and Nursing Considerations
4.1. Asthma prophylactic agent - Cromolyn sodium (Intal)
4.2. Respiratory stimulant - Doxaprome (Dopram)
4.3
Antihistamine and nasal decongestant
4.3.1. Pseudoephedrine (Sudafed)
4.3.2. Oxymetazone (Afrin)
4.3.3. Brompheniramine (Dimetame)
4.4. Anti-inflammatory- Beclomethasone (Vanceril)
5.
Legal implications
Teaching/Learning Activities:
1.
Lecture with discussion
2.
Handouts
3.
Selected media
Critical Thinking Focus:
Discussion and review of case study included in handout with emphasis on
nursing interventions and research.
Required Reading:
Aschenbrenner,D.S., Cleveland, L., & Venable,L.J., & (2002). Drug therapy
in nursing. (pp. 625-641; 642-670). Philadelphia: Lippincott
Respiratory
Rev.7/00 EL; 12/00 EL 5/01 EL;
12/01 EL,7/02 LC,11/02LC, 7/03/LC