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Biol302 Quiz6 March 23rd, 2011 Name__________________ Question 1 5pts: In 1928, Griffith’s Transforming Principle revealed the “transforming” compound from the heat-killed bacteria was DNA. _____True or False_____(circle one) Question 2 5pts: Griffith’s experiment took time because transformation had to occur in this organism:________. Avery, Macleod and McCarty made the procedure faster by setting up the transformation principle on ____________. Question 3 5pts: In 1943, 15 years later, Avery, Macleod and McCarty proved that the transforming compound was DNA in two critical ways. a) They showed that the transforming compound contained the same stoichiometry of four chemical elements commonly found in DNA. Name the five chemical elements found in DNA .__ __ __ __ __ b) They also showed that the transforming compound was destroyed with crude cell lysates containing this enzyme. _____________ Question 4 5pts: Looking back at your answer from Question 3a: If Avery, Macleod and McCarty found this chemical element___ in greater abundance than predicted for DNA, then the transforming compound would have been RNA. Extra Credit 5pts: In your lab, Calcium Chloride is used to transform DNA into bacteria. How did transformation work in Griffith’s model system? Be brief! 3 sentences max. _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________