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Biol302 Quiz6
March 23rd, 2011
Name__________________
Question 1 5pts:
In 1928, Griffith’s Transforming Principle revealed the “transforming” compound from
the heat-killed bacteria was DNA. _____True or False_____(circle one)
Question 2 5pts:
Griffith’s experiment took time because transformation had to occur in this
organism:________. Avery, Macleod and McCarty made the procedure faster by setting
up the transformation principle on ____________.
Question 3 5pts:
In 1943, 15 years later, Avery, Macleod and McCarty proved that the transforming
compound was DNA in two critical ways.
a) They showed that the transforming compound contained the same stoichiometry
of four chemical elements commonly found in DNA. Name the five chemical
elements found in DNA .__ __ __ __ __
b) They also showed that the transforming compound was destroyed with crude cell
lysates containing this enzyme. _____________
Question 4 5pts:
Looking back at your answer from Question 3a: If Avery, Macleod and McCarty found
this chemical element___ in greater abundance than predicted for DNA, then the
transforming compound would have been RNA.
Extra Credit 5pts:
In your lab, Calcium Chloride is used to transform DNA into bacteria.
How did transformation work in Griffith’s model system? Be brief!
3 sentences max.
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