Download Functional Food Ingredients: Probiotics

Functional Food Ingredients: Probiotics
Second generation probiotics
DSM Food Specialties has developed second generation probiotics that are the result of extensive screening of
a vast collection of micro-organisms with potential probiotic effects.
LAFTI® probiotics have recently been selected using today’s scientific techniques that focus on probiotic
properties that are now known to be important:
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stability
survival
proven health effects
safety
LAFTI®‘s unique benefits are the direct result of this Second-Generation screening
Available Probiotic strains:
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Lactobacillus acidophilus LAFTI® L10
Bifidobacterium lactis LAFTI ® B94
Lactobacillus paracasei LAFTI ® L26
What are probiotics?
A natural part of our body
The literal meaning of ‘probiotics’ is ‘for life’. Probiotics are a generic term for
naturally occurring ‘friendly’ bacteria that are beneficial for health, which
differentiates them from the ‘bad’ bacteria such as the well known Escherichia coli
and Salmonella, causing diarrhea and other intestinal problems. The most famous
probiotic families are Lactobacillus and Bifidobacterium.
Many different types of probiotic bacteria grow in the human digestive tract, and
together with other ‘friendly’ bacteria create a complex ecosystem in our intestines
called the intestinal microflora. Probiotics are thus a natural part of our body.
What makes a bacteria a probiotic?
Three checks
Why do we need probiotics?
Staying healthy
What makes a bacteria a probiotic?
Three checks
3. Survival of the bacteria
The bacteria must be alive when reaching the
human gut in order to provide the health
1. Safe for consumption
The bacteria to be used as probiotic must be a
'friendly' bacteria that is safe. By law, only safe
bacteria are accepted on the market. However,
the law does not yet regulate the definition
‘probiotics’. Anyone can claim a bacteria to be a
probiotic bacteria.
benefits.
It is important to note that probiotic
supplements in which the number of live
bacteria CFU is guaranteed until the end of
shelf life provide more certainty that you get a
sufficient dose of 'friendly' bacteria than a
supplement that only guarantees the dose "at
time of manufacturing".
2. Measurable beneficial effects on health
There must be scientific evidence available
demonstrating the beneficial effects of the
probiotic strain on our health. Very important is
that this scientific evidence must be for a
specific strain. For example, there are many
different Lactobacillus acidophilus strains, such
as Lactobacillus acidophilus LAFTI® L10. This
strain is a probiotic, since there is scientific
evidence available demonstrating the health
benefits for this specific strain.
Lactobacillus
acidophilus
LAFTI® L10
[family]
[species]
[strain]
What are probiotics?
A natural part of our body
Why do we need probiotics?
Staying healthy
Why do we need probiotics?
The important balance of the many different
Staying healthy
types of ‘friendly’ bacteria is easily
Probiotic bacteria play an important role in
digesting food as well as maintaining health.
They produce short chain fatty acids, which
promote colonic nutrition, help the body in
breaking down food, assist the absorption of
essential vitamins, and protect against
attack from ‘bad’ bacteria such as E. coli
and Salmonella.
disturbed, however. External factors such
as (antibiotic) medication, travel, changes in
diet and stress as well as internal influences
including microbial interactions and
intestinal secretions can have a negative
effect. As a result, undesirable ‘bad’
bacteria may invade, bringing symptoms
such as diarrhea, constipation, and other
bowel problems. Supplementing the daily
diet with probiotics keeps the important
balance of ‘friendly’ bacteria in place and
thereby helps maintain health.
What are probiotics?
A natural part of our body
What makes a bacteria a probiotic?
Three checks
What are LAFTI®
probiotics?
Second-generation
probiotics
LAFTI® probiotics are
second-generation probiotics. The first
probiotic strains were isolated many
decades ago without insight into strainrelated characteristics and their efficacy
was not always predictable or
repeatable. Additionally, many
‘probiotics’ currently available in the
market place lack the (strain-specific)
scientific evidence to demonstrate the
health benefits.
What makes LAFTI® probiotics special?
They bring the latest discoveries in the
field of probiotics
The second-generation screening
strategy has resulted in unique benefits such
as stability, survival and probiotic health
effects (see picture below).
Second-generation LAFTI® probiotics,
conversely, have built on knowledge
amassed over the years. LAFTI®
probiotics are the result of sophisticated
screening of a large number of bacteria
with potential probiotic effects.
LAFTI® second-generation probiotics
have recently been selected using
today’s scientific techniques that focus
on probiotic properties that are now
known to be important.
LAFTI®’s unique benefits include:
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Superior stability
In order to deliver health benefits, probiotics must
be alive when they arrive at their final destination:
the intestines. Heat, moisture, long shelf life and
inadequate packaging of the final product can all
easily inactivate probiotics, resulting in inferior
consumer products. LAFTI® probiotics have been
particularly developed to minimise the difficulties
associated with stability.
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Proven health effects
LAFTI® probiotics assist the immune system via
protection against ‘bad’ bacteria such as Listeria
and Salmonella. Also, clinical studies in humans
have been completed. These support LAFTI® as
having a beneficial effect on the general feeling of
well being and control of irritable bowel syndrome.
Excellent survival
Before arriving at their final destination, probiotics
must pass through the digestive system, including
the stomach. The acidic stomach and bile in the
digestive system can easily inactivate probiotics.
LAFTI® second-generation probiotics have been
specifically screened for acid and bile resistance
and survival in the human digestive system.
High concentration
LAFTI® probiotics are available in very high
concentrations, enabling for example dietary
supplement manufacturers to create cost-effective
supplements which are also efficacious. These
probiotics can be blend with other ingredients such
as prebiotics, vitamins and minerals, and they
allow consumers to take their daily dose of
probiotics in a single capsule.
Safety
All LAFTI® strains are safe to use in every
application.
Scientific information
Numerous studies have been undertaken
which support the positive effects of
probiotic microbial population. Choice of
strain depends on the desired health
DSM’s understanding of probiotic
cultures, combined with extensive and
continuing in vivo and in vitro research
ensures that the LAFTI® range provides
an optimal combination of important
benefits of the application.
probiotic properties with data available to
To claim efficacy beyond the point of
DSM will continue to provide scientific
manufacture, probiotics must remain
stable throughout shelf life and in the
gastro-intestinal tract where they are
designed to take effect. Our studies have
shown that LAFTI® survives well in the
human gastro-intestinal tract.
Sophisticated strain selection is key to
probiotic performance. DSM secondgeneration LAFTI® strains are specially
selected and formulated to meet the dual
demands of stability and survival,
delivering positive probiotic effects to
humans.
Clinical trials have been completed which
show that LAFTI® products are effective
probiotics.
These trials indicated promising results,
for example a beneficial effect on the
general feeling of well being and control
of irritable bowel syndrome. Other
studies have shown that all three LAFTI®
strains inhibit a range of pathogenic
bacteria in vitro.
support product and labelling claims.
backing for all LAFTI® strains and
support customers with advice and
support in product development and
labeling. Literature information is
available
from DSM upon request.