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Biological Level of Analysis Examples of how candidates may show evidence of critical thinking on questions using the assessment objective 2 command terms could include: 1. 2. 3. 4. 5. 6. 7. 8. analysis of the methodology and/or ethical considerations application of empirical support in relation to a given problem or issue using evidence from studies that support or disconfirm a theory, model or concept synthesis of concepts from different levels of analysis analysis of the interaction between biological, cognitive and cultural factors addressing the issue of universality versus cultural differences (etic and emic methodology) questioning the direction of cause and effect address potential gender similarities and differences Learning Objective 1. Outline principles that define the biological level of analysis. (SAQ) - Animal research is valid. - Emotion and behavior is caused by biological processes. - Patterns of behavior can be inherited. Research - Animal research is valid. > Rosenzweig (1972) - Emotion and behavior is caused by biological processes. >Neurotransmission >Hormones - Newcomer et al. - cortisol >Localization of brain function - Patterns of behavior can be inherited. >IQ - Bouchard et al. >Homosexuality >Homicide 2. Explain one study related to localization of - Hippocampus – transfers STM to LTM brain function. (SAQ) > Milner (1957) - Hippocampus – transfers STM to LTM > Corkin et al. (1997) – MRI – case study - Amygdala – strong emotional responses - Amygdala – strong emotional responses - Corpus callosum > Rauch et al. (1998) – PTSD - Corpus callosum > Gazzaniga – split-brain patients – case study 3. Interaction between cognition and physiology - Cortisol – memory (FRQ) > Newcomer et al. – experiment on humans, - Cortisol – memory cortisol injections - Amygdala, hippocampus, and cortisol – PTSD - Amygdala, hippocampus, and cortisol – PTSD Critical Analysis n/a n/a - Harvard Medical School – contradicts Yale University research, direction of cause and effect (which came first, the smaller hippocampus and amygdala or did the stressful (memory, hypersensitivity, etcetera) - Mirror neurons – social components of perception - Oxytocin – trust - Hippocampus – HM’s anterograde amnesia - Hippocampus – memory (memory, hypersensitivity, etcetera) > Yale University – prolonged stress damages the amygdala > Rauch et al. (1998) – male veterans and female survivors of sexual abuse > Bremner (2003) – prolonged stress damages the amygdala - Mirror neurons – social components of perception > Iacobone (2004) – correlational, MRI - Oxytocin – trust > Morhenn et al. (2008) – experiment – high levels of oxytocin create high levels of trust > New moms – correlational – higher oxytocin levels > New dads – lower testosterone levels - Hippocampus – HM’s anterograde amnesia - Hippocampus – memory > Maguire (2010) – taxi drivers with great spatial memory, hippocampus larger than normal – MRI, correlational event cause the shrinking?) > Twin research - Strength: same genetics, focus only on environmental impact - Culture/gender – Rauch et al. (1998) looked at both men and women, women tend to be victims of sexual violence more often than men - Methodology > Newcomer et al. – experiment - Strength – clear cause and effect, placebo group - Limitation – ecological validity (being injected with cortisol is not the same as experiencing cortisol naturally) 4. Evaluate the use of brain imaging technology (FRQ) - CT (computed tomography) – soft tissue in the brain, good for studying structures and damage - MRI (magnetic resonance imaging) – specific brain tissue scans - fMRI (functional MRI) – brain activity in specific brain areas - PET (positron emission topography) – abnormalities in brain activity - CT (computed tomography) – soft tissue in the brain, good for studying structures and damage > Ogden (2005) - hemineglect - MRI (magnetic resonance imaging) – specific brain tissue scans > Corkin et al. (1997) – temporal lobe - fMRI (functional MRI) – brain activity in specific brain areas > Brefcynski-Lewis et al. (2007) - meditation - PET (positron emission topography) – abnormalities in brain activity > Tierney et al. (2001) – case study on MA, compensation/language *Look on the yellow study packet for more research (2.7) - CT (computed tomography) – soft tissue in the brain, good for studying structures and damage > Strengths - good for studying structures and damage > Limitations - doesn’t measure brain activity - harder to manipulate - doesn’t show clear blood flow - MRI (magnetic resonance imaging) – specific brain tissue scans > Strengths - safer than CT scans - pictures can be manipulated - shows shrinking of brain parts > Limitations - can be invasive - fMRI (functional MRI) – brain activity in specific brain areas > Strengths - safer than CT scans - pictures can be manipulated - can measure brain activity - more precise than PET or MRI - no radioactive injections > Limitations - can be invasive - doesn’t show cause and effect relationship - PET (positron emission topography) – abnormalities in brain activity > Strengths - shows brain activity - not just a picture of the brain > Limitations - can be invasive 5. Environment impacting physiological - Brain plasticity, dendritic branching - Rosenzweig (1971) processes > Rosenzweig (1972) – enriching environment > Strengths – lab rats (high control), randomly - Brain plasticity, dendritic branching impact brain density selected, clear cause and effect, implies that - SAD (seasonal affective disorder) – melatonin > Sneddon et al. (2002) – pigs in enriched and humans will also be impacted by their – lack of sunlight during specific seasons relates impoverished environments – pigs in enriched environment, brain size is not important (brain - to circadian rhythm environments learned faster weight is) - PTSD > Brefcynski-Lewis et al. (2007) – meditation, > Limitations – never showed how it impacted visual cortex, areas of the brain related to behavior (follow-up research did) attention > Ethical considerations – euthanized rats > Draganski et al. (2004) – juggling - Brefcynski-Lewis et al. (2007) > Maguire et al. (2000) – taxi drivers, spatial > Limitations memory, hippocampi - Participants – based on a personal > Tierney et al. (2001) – case study on MA, recording system, Asians and Caucasians compensation/language (not a balanced cultural component) - SAD (seasonal affective disorder) – melatonin - Maguire et al. (2007) – lack of sunlight during specific seasons relates > Limitations – studied only male London taxi to circadian rhythm drivers, only scanned their brains > Avery et al. (2001) – dawn simulation, bright light therapy, and placebo red light – only dawn simulation and bright light therapy effectively adjusted the sleep cycle - PTSD – amygdala, hippocampus, and cortisol > Yale University – prolonged stress damages the amygdala > Rauch et al. (1998) – male veterans and female survivors of sexual abuse > Bremner (2003) – prolonged stress damages the amygdala 6. Neurotransmission - Dopamine – voluntary movement, pleasureseeking, goal-directed behavior, motivation, addiction, Parkinson’s disease (too little dopamine, need L-dopa), schizophrenia (too much dopamine, need chlorpromazine) - Serotonin – mood regulation - Acetylcholine (ACh) – synaptic plasticity, learning, STM 7. Hormones - Adrenaline – adrenal medulla, emotion - Cortisol – adrenal gland, memory - Oxytocin – hypothalamus tells pituitary gland in the brain to secrete hormone, trust, autism - Melatonin – pineal gland in the brain, sleep cycle - Dopamine – voluntary movement, pleasureseeking, goal-directed behavior, motivation, addiction, Parkinson’s disease (too little dopamine, need L-dopa), schizophrenia (too much dopamine, need chlorpromazine) > Berridge and Kringelback (2009) – correlational study using brain scans between pleasure, dopamine, and specific brain locations > Fisher (2004) – addiction to love - Serotonin – mood regulation > Bonson et al. (1996) – LSD usage impacted by Prozac – survey – Prozac decreases symptoms of depression and made LSD less effective - Acetylcholine (ACh) – synaptic plasticity, learning, STM > Martinez and Kessner (1991) – experiment on rats – the role of ACh on memory formation – rats given injections (ACh blocked, make rats more responsive to ACh by cleaning out ACh, control) learn a maze – group with ACh cleaned out most successful - Adrenaline – adrenal medulla, emotion > Schachter and Singer – link between cognition and emotion, different emotions can have the same physiological changes, emotional response is based on contextual clues, physiological changes – experiment - Injection of adrenaline, different side effect information given to participants - Bonson et al. (1996) - survey > Strengths: survey can be mass-distributed, participants under treatment for depression > Limitations: people can lie on survey - Berridge and Kringelback (2009) correlational research > Limitation: no clear cause and effect - Neurotransmission not different across genders and cultures - Schachter and Singer > Strengths: experiment (clear cause and effect), deception (participants did not know what they were getting injected with) > Limitations: accuracy of emotions, some people may minimize expression of strong emotions in survey responses - Oxytocin 8. Genetics (FRQ) - Twin research - Depression - Schizophrenia - Two different contexts > Euphoria – encouraged to join in games using office equipment > Anger – confederate angry about personal nature of questionnaire - Observation, survey - Results: those who were not given the correct information were happiest - Cortisol – adrenal gland, memory > Newcomer et al. – experiment on humans, cortisol injections > PTSD - Oxytocin – hypothalamus tells pituitary gland in the brain to secrete hormone, trust, autism > Baumgartner et al. (2008) – money games – fMRI > Morhenn et al. (2008) – experiment – high levels of oxytocin create high levels of trust > Yale (2012) – low levels of oxytocin present in patients with ASD (autism spectrum disorder), low trust levels > Holt-Lunstad et al. (2008) – trust and bonding between husband and wife > New moms – correlational – higher oxytocin levels > New dads – lower testosterone levels - Melatonin – pineal gland in the brain, sleep cycle > Avery et al. (2001) – dawn simulation, bright light therapy, and placebo red light – only dawn simulation and bright light therapy effectively adjusted the sleep cycle > Lewy et al. (2006) – experiment – supported Avery et al. (2001) - Twin research > Bailey and Pillard (1991) - homosexuality > Bouchard - Depression > Caspi et al. (2003) – longitudinal, > Gender - New moms – correlational – higher oxytocin levels - New dads – lower testosterone levels - Methodology > Experiments > Surveys > Correlational - Santilla et al. – criticized Bailey and Pillard (1991) – homosexuality and IQ - Caspi et al. (2003) > 5-HTT gene present in most people, many people susceptible to depression, but no cause 9. Evolution (FRQ) - Homosexuality - Homicide - Disgust correlational – relationship between the 5HTT gene and depression after a stressful event - Schizophrenia > Heston (1966) – adoption research, mom had schizophrenia, see if adopted child showed same symptoms > Read et al. (2004) – relationship between physical and sexual abuse in childhood and the development of schizophrenia - Homosexuality > Zietsch et al. (2008) > Bailey and Pillard (1991) > Bouchard - Homicide > Homicide Adaptation Theory (HAT) – being able to kill gives an individual a psychological advantage - Durrant (2009) – a weakness in HAT – homicide is the byproduct of evolution and has no advantage - Disgust > Curtis et al. (2004) > Fessler et al. (2005) – supports Curtis et al. (2004) – web-based survey, many people can participate – investigated disgust sensitivity in first trimester of pregnancy - Disgust an adaptation for mothers, makes mothers more sensitive for protection and effect > Limitations: survey, directional cause and effect issues (did the stressful event cause depression or the gene) - Ethical considerations - right to participant, right to withdrawal, confidentiality, cause and effect relationship, loss of self-control with too much emphasis on genes