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spums j 26/1 - Rubicon Research Repository
spums j 26/1 - Rubicon Research Repository

... phase or an increase in the myocardial oxygen demand/ supply ratio caused by the hypertension induced upon release. However, it is unlikely that these symptoms would by seen without either repeated and prolonged manoeuvres or associated physical activity. Kern et al., in a study of subjects with nor ...
The role of electrocardiogram in the diagnosis of dextrocardia with
The role of electrocardiogram in the diagnosis of dextrocardia with

... anatomies are reversed. Dextrocardia with situs inversus occurs at birth but its diagnosis may be in adulthood. This case advances knowledge by graphically describing the unusual electrocardiographic features of dextrocardia in a young adult. Case presentation: We report a case of a 22-year-old Nige ...
Heart Failure with Preserved Ejection Fraction
Heart Failure with Preserved Ejection Fraction

... failure (HF) had a left ventricular ejection fraction in the normal range. This entity has been termed “heart failure with preserved ejection fraction (HFPEF).” Previous studies have indicated that patients who have HFPEF tend to be older, female, and to have a history of hypertension. ...
Cardiac Resynchronization Therapy for Patients With Left
Cardiac Resynchronization Therapy for Patients With Left

... The percentage of patients hospitalized for heart failure was 27% in controls and 19% in patients assigned to CRT (RR, 0.63; 95% CI, 0.43-0.93) (FIGURE 2), and all-cause mortality was 13.2% in patients assigned to CRT vs 15.5% in controls (RR, 0.78; 95% CI, 0.67-0.91) (FIGURE 3). The survival benefi ...
Trans-Catheter Pulmonary Valve Implantation: Procedure
Trans-Catheter Pulmonary Valve Implantation: Procedure

... patch size) and the stent apposition area may be narrow. This is why anatomy after RVOT patch repair is often considered unfavorable for TPVI and is therefore not recommended by current guidelines. However, a recent study showed that this procedure may be feasible with the SAPIEN valves [16]. Furthe ...
PDF-link: 199904020112
PDF-link: 199904020112

... Discussion The shape and the location of the strength-duration curve for cardiac pacing have been mostly determined during invasive electrophysiologic studies and pacemaker implantation procedures. It is known that the strength-duration curve [21-24] may be shifted upward and to the right in pacing ...
alterations in pulmonary blood flow distribution in heart diseases
alterations in pulmonary blood flow distribution in heart diseases

... Utilizing the 1311-MAA (macroaggregated albumin labeled with iodine-131) scintillation scanning method, regional pulmonary blood flow distribution was studied in 47 cardiac patients with pulmonary hypertension. Remarkable increase of blood flow in the upper zones of the lung together with decrease i ...
Therapeutic effect of MG132 on diabetic cardiomyopathy is
Therapeutic effect of MG132 on diabetic cardiomyopathy is

... From clinical setting, there is an urgent need for an efficient approach that can provide a ...
About Your Pacemaker
About Your Pacemaker

... contractions and allows the heart to beat rhythmically. Impulses are then carried from the upper chambers into the lower chambers which then contract. This contraction is what you know as a heartbeat. At rest, a healthy heart beats 60 to 80 times per minute, which is about 100,000 times per day. Dur ...
Syncope - Brain 101
Syncope - Brain 101

...  Massage, NOT occlusion  Duration: 5-10 sec  Posture – supine & erect ...
Higher Serum Concentrations of N-Terminal Pro-B
Higher Serum Concentrations of N-Terminal Pro-B

... All analyses were performed with SAS, version 9.3 (SAS Institute, Cary, NC, USA). Baseline descriptive data (shown in Table 1), expressed as the mean ± standard deviation (SD) or as median and 5th to 95th percentile depending on distribution or proportions in percent, were compared with parametric o ...
Dynamic myocardial contractile parameters from left - AJP
Dynamic myocardial contractile parameters from left - AJP

... contraction, length-tension and force-velocity, are actually special cases with respect to contraction time and load, i.e., peak force during isometric contraction in the case of length-tension and initial shortening velocity against isotonic load in the case of force-velocity. These descriptors are ...
Migraine aura without headache: Benign, but a diagnosis of exclusion M ■
Migraine aura without headache: Benign, but a diagnosis of exclusion M ■

... rological symptoms that may also occur. The most common visual symptom in an aura with or without a headache is photopsia (unformed flashes of light). Teichopsia, also known as fortification spectrum, is believed to be the most diagnostic of migraine. It involves a bright, zigzag border that looks ...
Rupture of Right Sinus of Valsalva Aneurysm with Alternating
Rupture of Right Sinus of Valsalva Aneurysm with Alternating

... arteriosus, ruptured SVA, cervical venous hum, mammary soufflé of pregnancy, coronary arteries, great vessel, or hemodialysis AV fistulas. Echocardiography remains the best non-invasive diagnostic tool, and it can detect the wall of the aneurysm and the disturbed flow within the aneurysm or at the s ...
Combined angiotensin receptor blocker and ACE inhibitor on
Combined angiotensin receptor blocker and ACE inhibitor on

... systemic resistance, Ea, and end-diastolic volume were significantly decreased and Ees/Ea and SV were significantly increased. Comparisons among treatment groups showed that ARB ⫹ ACEI significantly decreased end-diastolic pressure and volume, total systemic resistance, and Ea and significantly incr ...
Normal age-related changes in left ventricular function: Role of
Normal age-related changes in left ventricular function: Role of

... ClinicalTrials.Gov identifier NCT01504828). All subjects had measurements of pulse wave velocity by the Vicorder device and the MRI on the same day within 2 h. ...
Perioperative Management of Pulmonary Hypertension
Perioperative Management of Pulmonary Hypertension

... complications following noncardiac surgery, the few studies that do exist demonstrate the risk associated with procedures. Therefore, medical optimization is critical. During perioperative risk assessment, one should take into account the type of surgery, the patient’s functional status, the severit ...
Brugada Syndrome (2015)
Brugada Syndrome (2015)

... It  can  also  appear  as  a  consequence  of  structural  changes  in  the  right  ventricular  outflow  tract from a variety of causes. BrS is reported to be responsible for 4% of all sudden deaths  and 20% of sudden deaths in those without structural heart disease and is a leading cause of  death ...
Alcohol and arrhythmias: a comprehensive review.
Alcohol and arrhythmias: a comprehensive review.

... alcohol(23). Unfortunately, this study lacks data on drink type or drinking pattern. In the British Regional Heart Study there was a two fold increase in SCD in individuals who consumed six or more drinks/day, a finding most evident in cases where there was no preexisting heart disease (Figure 3)(24 ...
Andropoulos Chapter
Andropoulos Chapter

... perfusion, potentially creating ischemia from the imbalance of decreased myocardial oxygen delivery and increased oxygen demand. Due to this volume burden, the left ventricle eventually will dilate and hypertrophy producing increased left ventricular end-diastolic pressure followed by increased left ...
AHA Scientific Statement
AHA Scientific Statement

... systematic classification of CKD in large part is based on the efforts of Andrew Levey and colleagues, who published the K/DOQI (Kidney Disease Outcomes Quality Initiative) clinical practice guidelines for CKD.7 The original schema somewhat arbitrarily defined stages 1 to 5 CKD on the basis of estim ...
Pharmacology Objectives 9
Pharmacology Objectives 9

... moderate congestive heart failure associated with sinus rhythm. Digoxin confers the added benefits of reduced hospitalization and slowed progression to persons with mild to moderate heart failure receiving diuretics and ACE inhibitors. It does not reduce mortality and should therefore only be used t ...
PDF-1 - RUcore - Rutgers University
PDF-1 - RUcore - Rutgers University

... did not receive adequate oxygen, proper medical care, and there was no ambulance present (Associated Press, 2012). ...
Heart rate as a marker of incidence and prognosis of cardiovascular
Heart rate as a marker of incidence and prognosis of cardiovascular

... secondary care data, myocardial infarction disease registry and mortality data. Additionally, to establish a clinical cohort of people with CAD, I consented, recruited and collected anthropometric and biomarker data including RHR from patients attending chest pain clinics and angiography labs in Lon ...
Right ventricular failure in patients with the HeartMate
Right ventricular failure in patients with the HeartMate

... and there is a question about whether these precepts are still applicable for continuous-flow pumps. The development of RVF in patients with an LVAD has a direct effect on mortality and is associated with prolonged length of intensive care unit and hospital stay.5-10 Patients with severe RVF requiri ...
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Coronary artery disease



Coronary artery disease (CAD), also known as ischemic heart disease (IHD), atherosclerotic heart disease, atherosclerotic cardiovascular disease, and coronary heart disease, is a group of diseases that includes: stable angina, unstable angina, myocardial infarction, and sudden coronary death. It is within the group of cardiovascular diseases of which it is the most common type. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. Usually symptoms occur with exercise or emotional stress, last less than a few minutes, and gets better with rest. Shortness of breath may also occur and sometimes no symptoms are present. The first sign is occasionally a heart attack. Other complications include heart failure or an irregular heartbeat.Risk factors include: high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol, among others. Other risks include depression. The underlying mechanism involves atherosclerosis of the arteries of the heart. A number of tests may help with diagnoses including: electrocardiogram, cardiac stress testing, coronary computed tomographic angiography, and coronary angiogram, among others.Prevention is by eating a healthy diet, regular exercise, maintaining a healthy weight and not smoking. Sometimes medication for diabetes, high cholesterol, or high blood pressure are also used. There is limited evidence for screening people who are at low risk and do not have symptoms. Treatment involves the same measures as prevention. Additional medications such as antiplatelets including aspirin, beta blockers, or nitroglycerin may be recommended. Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe disease. In those with stable CAD it is unclear if PCI or CABG in addition to the other treatments improve life expectancy or decreases heart attack risk.In 2013 CAD was the most common cause of death globally, resulting in 8.14 million deaths (16.8%) up from 5.74 million deaths (12%) in 1990. The risk of death from CAD for a given age has decreased between 1980 and 2010 especially in the developed world. The number of cases of CAD for a given age has also decreased between 1990 and 2010. In the United States in 2010 about 20% of those over 65 had CAD, while it was present in 7% of those 45 to 64, and 1.3% of those 18 to 45. Rates are higher among men than women of a given age.
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