Aortic involvement in patients with a bicuspid aortic valve
... C, differs in BAV aneurysms compared to those aneurysms associated with TAVs. Thus, the cystic medial degeneration associated with BAV disease may be related to imbalance between proteolytic enzymes and their inhibitors in the aortic wall. Plasma concentrations of MMP-2 have also been reported to be ...
... C, differs in BAV aneurysms compared to those aneurysms associated with TAVs. Thus, the cystic medial degeneration associated with BAV disease may be related to imbalance between proteolytic enzymes and their inhibitors in the aortic wall. Plasma concentrations of MMP-2 have also been reported to be ...
atrial fibrillation
... fibrillation that occurs in young adults who do not have cardiac disease, diabetes mellitus, or hypertension. There is no standard, accepted definition of lone atrial fibrillation and use of the term is discouraged by the current (2014) guidelines from the American Heart Association (AHA) and the Am ...
... fibrillation that occurs in young adults who do not have cardiac disease, diabetes mellitus, or hypertension. There is no standard, accepted definition of lone atrial fibrillation and use of the term is discouraged by the current (2014) guidelines from the American Heart Association (AHA) and the Am ...
Secundum atrial septal defect in the adult. Clinical
... influence P-wave duration, suggesting irreversible electrophysiological abnormalities known to be associated with the development of atrial fibrillation. This would favour early intervention in order to prevent late atrial fibrillation in ASD. 3) Cardiac remodelling after ASD closure in the adult is ...
... influence P-wave duration, suggesting irreversible electrophysiological abnormalities known to be associated with the development of atrial fibrillation. This would favour early intervention in order to prevent late atrial fibrillation in ASD. 3) Cardiac remodelling after ASD closure in the adult is ...
Secundum atrial septal defect in the adult. Clinical
... influence P-wave duration, suggesting irreversible electrophysiological abnormalities known to be associated with the development of atrial fibrillation. This would favour early intervention in order to prevent late atrial fibrillation in ASD. 3) Cardiac remodelling after ASD closure in the adult is ...
... influence P-wave duration, suggesting irreversible electrophysiological abnormalities known to be associated with the development of atrial fibrillation. This would favour early intervention in order to prevent late atrial fibrillation in ASD. 3) Cardiac remodelling after ASD closure in the adult is ...
Thesis, Emmanuel Moss 20110625 Final
... throughout in 2 canines. Surface area of REPOL∆ diminished with successive denervation, from 365±252 at baseline to 53±106mm2 following RAGP ablation (p<0.03). With retrograde denervation, chronotropic and repolarisation changes were suppressed following RAGP ablation in two canines, and following A ...
... throughout in 2 canines. Surface area of REPOL∆ diminished with successive denervation, from 365±252 at baseline to 53±106mm2 following RAGP ablation (p<0.03). With retrograde denervation, chronotropic and repolarisation changes were suppressed following RAGP ablation in two canines, and following A ...
Coupling interval from slow to tachycardiac pacing - AJP
... alternans would change with cardiac contractile conditions at the same beating rate. However, we accidentally observed that the interbeat alternation pattern and amplitude of the sustained contractile alternans induced by tachycardiac pacing varied considerably with a single coupling beat interval b ...
... alternans would change with cardiac contractile conditions at the same beating rate. However, we accidentally observed that the interbeat alternation pattern and amplitude of the sustained contractile alternans induced by tachycardiac pacing varied considerably with a single coupling beat interval b ...
Pulmonary arterial hypertension in children
... system (table 1). This classification system categorises pulmonary vascular disease by common clinical features. This classification reflects the recent advances in the understanding of pulmonary hypertensive diseases as well as recognising the similarity between primary pulmonary hypertension and p ...
... system (table 1). This classification system categorises pulmonary vascular disease by common clinical features. This classification reflects the recent advances in the understanding of pulmonary hypertensive diseases as well as recognising the similarity between primary pulmonary hypertension and p ...
The Effect of Wai Tan Kung on Autonomic Nervous Modulation in the
... WTK is a traditional Taiwanese mind-body exercise that is unique due to its use of whole-body trembling and coordinated movements. The basic principle of WTK exercise is to get rid of distracting ideas and allow one’s inner energy to rise up automatically from inside and make the whole body tremble ...
... WTK is a traditional Taiwanese mind-body exercise that is unique due to its use of whole-body trembling and coordinated movements. The basic principle of WTK exercise is to get rid of distracting ideas and allow one’s inner energy to rise up automatically from inside and make the whole body tremble ...
Stretch-mediated cardiac hypertrophy and extracellular matrix
... Cardiovascular diseases are one of the most frequent causes of death worldwide1 and are, in the Netherlands, responsible for approximately 30% of all deaths2. Heart failure accounts for 16% of all cardiac deaths3. Heart failure develops secondary to cardiac overload. This overload may originate from ...
... Cardiovascular diseases are one of the most frequent causes of death worldwide1 and are, in the Netherlands, responsible for approximately 30% of all deaths2. Heart failure accounts for 16% of all cardiac deaths3. Heart failure develops secondary to cardiac overload. This overload may originate from ...
Pulmonary embolism: what have we learned since Virchow?
... 630,000 patients per year who have pulmonary embolism, the diagnosis was made and treatment initiated in only 163,000 patients (25%). The lack of specificity of the clinical diagnosis became evident when pulmonary angiography became available as a “gold standard” for the diagnosis of pulmonary embol ...
... 630,000 patients per year who have pulmonary embolism, the diagnosis was made and treatment initiated in only 163,000 patients (25%). The lack of specificity of the clinical diagnosis became evident when pulmonary angiography became available as a “gold standard” for the diagnosis of pulmonary embol ...
Electrophysiology Products
... The use of catheters or cables with unprotected male pin connectors present a risk of electrical hazard. Inadvertent attachment of pin connectors to power supply sockets or connectors could result in electrocution of the patient or operator. Misconnection of the pins could also lead to inappropriate ...
... The use of catheters or cables with unprotected male pin connectors present a risk of electrical hazard. Inadvertent attachment of pin connectors to power supply sockets or connectors could result in electrocution of the patient or operator. Misconnection of the pins could also lead to inappropriate ...
Development of Heart Failure and Congenital Septal
... examined by light microscopy. To quantify the incidence of septal defects, neonatal hearts (36 eNOS⫺/⫺, 34 eNOS⫹/⫺ , and 41 eNOS⫹/⫹) were fixed in 10% buffered formalin, and a standard procedure for microdissection of the heart was applied according to methods described previously.18,19 Briefly, the ...
... examined by light microscopy. To quantify the incidence of septal defects, neonatal hearts (36 eNOS⫺/⫺, 34 eNOS⫹/⫺ , and 41 eNOS⫹/⫹) were fixed in 10% buffered formalin, and a standard procedure for microdissection of the heart was applied according to methods described previously.18,19 Briefly, the ...
When Calcium Turns Arrhythmogenic: Intracellular Calcium
... believed to cause delayed afterdepolarizations and triggered activity (4). Recently, myocardial Ca2+ overload has been closely related to the initiation of tachyarrhythmic activity in isolated hearts or cardiomyocytes of rats and ferrets, as bioluminescence or fluorescence of intracellular Ca2+ indi ...
... believed to cause delayed afterdepolarizations and triggered activity (4). Recently, myocardial Ca2+ overload has been closely related to the initiation of tachyarrhythmic activity in isolated hearts or cardiomyocytes of rats and ferrets, as bioluminescence or fluorescence of intracellular Ca2+ indi ...
Boundless Study Slides
... • diastolic blood pressure The lowest pressure within the bloodstream, occurring between heartbeats because of a diastole. • diastolic pressure The minimum arterial pressure between contractions, when the heart expands and refills. • diastolic pressure The minimum arterial pressure between contracti ...
... • diastolic blood pressure The lowest pressure within the bloodstream, occurring between heartbeats because of a diastole. • diastolic pressure The minimum arterial pressure between contractions, when the heart expands and refills. • diastolic pressure The minimum arterial pressure between contracti ...
Aortic Valve and Ascending Aorta Guidelines for Management and
... *Data available from clinical trials or registries about the usefulness/efficacy in different subpopulations, such as gender, age, history of diabetes, history of prior myocardial infarction, history of heart failure, and prior aspirin use. A recommendation with Level of Evidence B or C does not impl ...
... *Data available from clinical trials or registries about the usefulness/efficacy in different subpopulations, such as gender, age, history of diabetes, history of prior myocardial infarction, history of heart failure, and prior aspirin use. A recommendation with Level of Evidence B or C does not impl ...
Bicuspid aortic and pulmonary valves complicated by acute aortic
... sporting activities, given the increased risk of aortic rupture [37]. Furthermore, because the aortic dilatation rate may significantly differ between individual patients, only specific follow-up measurements can determine individual size-dependent aortic risk [8]. ...
... sporting activities, given the increased risk of aortic rupture [37]. Furthermore, because the aortic dilatation rate may significantly differ between individual patients, only specific follow-up measurements can determine individual size-dependent aortic risk [8]. ...
The Classically Cardioprotective Agent Diazoxide Elicits
... tachyarrhythmias (VTs) under conditions of metabolic demand. Activation of mitochondrial adenosine triphosphatesensitive potassium (KATP) channels by low-dose diazoxide (DZX) improves hypoglycemia-related complications, metabolic function, and triglyceride and free fatty acid levels and reverses wei ...
... tachyarrhythmias (VTs) under conditions of metabolic demand. Activation of mitochondrial adenosine triphosphatesensitive potassium (KATP) channels by low-dose diazoxide (DZX) improves hypoglycemia-related complications, metabolic function, and triglyceride and free fatty acid levels and reverses wei ...
Depolarization wave and mechanics in the paced heart : model and
... Myofiber contraction is initiated by depolarization of the cell membrane. A coherent contraction of all myofibers in the cardiac walls is a requisite for an efficient pump function of the heart as a whole. In the heart, a specialized conduction system enables a fast spread of myocyte depolarization. ...
... Myofiber contraction is initiated by depolarization of the cell membrane. A coherent contraction of all myofibers in the cardiac walls is a requisite for an efficient pump function of the heart as a whole. In the heart, a specialized conduction system enables a fast spread of myocyte depolarization. ...
Two components of delayed rectifier K+ current in heart: molecular
... a pronounced dominant negative effect on the original isoform of KvLQT1 (isoform 1) when they are co-expressed in Xenopus oocytes. Péréon et al demonstrated that the overall expression of KvLQT1 (isoform 1, isoform 2) and minK genes in the ventricle was similar among the epicardial, midmyocadial and ...
... a pronounced dominant negative effect on the original isoform of KvLQT1 (isoform 1) when they are co-expressed in Xenopus oocytes. Péréon et al demonstrated that the overall expression of KvLQT1 (isoform 1, isoform 2) and minK genes in the ventricle was similar among the epicardial, midmyocadial and ...
DOI: 10.1161/CIRCULATIONAHA.106.177031 published online Aug
... It is important that the medical profession play a significant role in critically evaluating the use of diagnostic procedures and therapies as they are introduced and tested in the detection, management, or prevention of disease states. Rigorous and expert analysis of the available data documenting ...
... It is important that the medical profession play a significant role in critically evaluating the use of diagnostic procedures and therapies as they are introduced and tested in the detection, management, or prevention of disease states. Rigorous and expert analysis of the available data documenting ...
Multiscale characterization of cardiac remodeling induced by intrauterine growth restriction, at
... The heart is a central organ in the fetal adaptive mechanism to placental insufficiency and cardiac dysfunction is recognized as being among the central pathophysiologic feature of both early- and late-onset IUGR [26]. The prediction of mortality, morbidity and the subclinical cardiac dysfunction as ...
... The heart is a central organ in the fetal adaptive mechanism to placental insufficiency and cardiac dysfunction is recognized as being among the central pathophysiologic feature of both early- and late-onset IUGR [26]. The prediction of mortality, morbidity and the subclinical cardiac dysfunction as ...
Guidelines - Lettre de l`UFCV N°58
... It is important that the medical profession play a significant role in critically evaluating the use of diagnostic procedures and therapies as they are introduced and tested in the detection, management, or prevention of disease states. Rigorous and expert analysis of the available data documenting ...
... It is important that the medical profession play a significant role in critically evaluating the use of diagnostic procedures and therapies as they are introduced and tested in the detection, management, or prevention of disease states. Rigorous and expert analysis of the available data documenting ...
Pradyot Saklani, Andrew Krahn and George Klein Syncope doi
... A heterogeneous group of disorders consisting of vasovagal syncope, situational syncope, carotid sinus syncope, and others are generally grouped as reflex or neurally mediated syncope. Although the provoking stimuli differ, they share sequelae of hypotension and vasodilatation with relative or absol ...
... A heterogeneous group of disorders consisting of vasovagal syncope, situational syncope, carotid sinus syncope, and others are generally grouped as reflex or neurally mediated syncope. Although the provoking stimuli differ, they share sequelae of hypotension and vasodilatation with relative or absol ...
ACC/AHA/ESC Practice Guidelines
... that might be perceived as real or potential conflicts of interest. Writing Committee members are also strongly encouraged to declare a previous relationship with industry that might be perceived as relevant to guideline development. If a Writing Committee member develops a new relationship with ind ...
... that might be perceived as real or potential conflicts of interest. Writing Committee members are also strongly encouraged to declare a previous relationship with industry that might be perceived as relevant to guideline development. If a Writing Committee member develops a new relationship with ind ...
ACC/AHA/ESC 2006 Guidelines for the
... that might be perceived as real or potential conflicts of interest. Writing Committee members are also strongly encouraged to declare a previous relationship with industry that might be perceived as relevant to guideline development. If a Writing Committee member develops a new relationship with ind ...
... that might be perceived as real or potential conflicts of interest. Writing Committee members are also strongly encouraged to declare a previous relationship with industry that might be perceived as relevant to guideline development. If a Writing Committee member develops a new relationship with ind ...
Coronary artery disease
Coronary artery disease (CAD), also known as ischemic heart disease (IHD), atherosclerotic heart disease, atherosclerotic cardiovascular disease, and coronary heart disease, is a group of diseases that includes: stable angina, unstable angina, myocardial infarction, and sudden coronary death. It is within the group of cardiovascular diseases of which it is the most common type. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. Usually symptoms occur with exercise or emotional stress, last less than a few minutes, and gets better with rest. Shortness of breath may also occur and sometimes no symptoms are present. The first sign is occasionally a heart attack. Other complications include heart failure or an irregular heartbeat.Risk factors include: high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol, among others. Other risks include depression. The underlying mechanism involves atherosclerosis of the arteries of the heart. A number of tests may help with diagnoses including: electrocardiogram, cardiac stress testing, coronary computed tomographic angiography, and coronary angiogram, among others.Prevention is by eating a healthy diet, regular exercise, maintaining a healthy weight and not smoking. Sometimes medication for diabetes, high cholesterol, or high blood pressure are also used. There is limited evidence for screening people who are at low risk and do not have symptoms. Treatment involves the same measures as prevention. Additional medications such as antiplatelets including aspirin, beta blockers, or nitroglycerin may be recommended. Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe disease. In those with stable CAD it is unclear if PCI or CABG in addition to the other treatments improve life expectancy or decreases heart attack risk.In 2013 CAD was the most common cause of death globally, resulting in 8.14 million deaths (16.8%) up from 5.74 million deaths (12%) in 1990. The risk of death from CAD for a given age has decreased between 1980 and 2010 especially in the developed world. The number of cases of CAD for a given age has also decreased between 1990 and 2010. In the United States in 2010 about 20% of those over 65 had CAD, while it was present in 7% of those 45 to 64, and 1.3% of those 18 to 45. Rates are higher among men than women of a given age.