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2013 ESC guidelines on the management of stable coronary artery
2013 ESC guidelines on the management of stable coronary artery

... probability for the presence of epicardial CAD. One must be aware, however, that the manifestations of chest pain are so variable—even within a single patient—that a distinction between symptoms caused by an epicardial stenosis and symptoms caused by functional disease at the level of the microvascu ...
Predisposing factors of valve regurgitation in complete
Predisposing factors of valve regurgitation in complete

... annuloplasty (2,10,14). As described previously, the first 6 months of life should be the golden time for definitive repair (6,7,10,13,14,18) because not only preoperative regurgitation, but also pulmonary vascular obstructive disease hardly develops at this period (19,20). We have been performing c ...
(PIL) - (eMC)
(PIL) - (eMC)

... A great variability has been noted between paediatric patients in regard to both the plasma concentration necessary to initiate a hemodynamic response (threshold) and the rate of hemodynamic response to increasing plasma concentrations, which demonstrates that the required dose for children cannot b ...
Reduced Ventricular Proarrhythmic Potential of the Novel Combined
Reduced Ventricular Proarrhythmic Potential of the Novel Combined

... normal canine heart, this compound exerts atrial-predominant electrophysiological effects both in vivo and in vitro.9 In the anesthetized methoxamine-sensitized rabbit model of torsades de pointes ventricular tachyarrhythmia (TdP), intravenous AZD1305 increased the QT interval without inducing ventr ...
Correlation between P Wave Dispersion, QRS Duration and QT
Correlation between P Wave Dispersion, QRS Duration and QT

... diagnosis of acute myocardial infarction can be made if workup reveals the typical rise and fall of biochemical markers of myocardial necrosis along with either the development of pathologic Q waves or the presence [on ECG or in the setting of a coronary intervention] of ischemic STsegment changes. ...
Ruptured Left Sinus of Valsalva Aneurysm
Ruptured Left Sinus of Valsalva Aneurysm

... to 90% of cases, right sinus of valsalva is involved, in 10% the noncoronary sinus is affected and the left sinus is very rarely affected.1 SVA are usually of two types—congenital and acquired mostly due to syphilis, atherosclerosis or endocarditis.2,3 Transesophageal echocardiography (TEE) and thor ...
Postural Variation in Second Sound Splitting
Postural Variation in Second Sound Splitting

Coronary Computed Tomography Angiography for the Diagnosis of
Coronary Computed Tomography Angiography for the Diagnosis of

... segments. Raff et al [28] did not exclude segments based on size, but excluded 17% of segments from the segment-based analysis because of inadequate visualization, predominantly due to either calcification or motion artifact. Leber et al [18] excluded 4 of 59 patients from their analysis because of ...
angiographic study of the normal coronary artery in patients
angiographic study of the normal coronary artery in patients

... fluctuations within the left and right coronary arteries (Frederic et al, 2003). The functional value of such anastomoses is variable, but they appear to become more effective in slowly progressive pathological condition, it may become valuable and most effective in conditions of hypoxia and in chro ...
Clinical recommendations of cardiac magnetic resonance, Part II
Clinical recommendations of cardiac magnetic resonance, Part II

... myocarditis, can lead to false negative results for myocardial edema.6 Hyperemia identification, as proposed by Lake Louise criteria, is very challenging and poorly used in the clinical setting. Recently, postcontrast cine steadystate free precession (SSFP) sequences were proposed as a new method fo ...
Full-Text PDF
Full-Text PDF

... Doxorubicin (DOX) belongs to the family of anthracyclines, and has been used to against cancer since late 1960s. It is the most effective anticancer drugs. However, studies of cardiotoxic effects of DOX have been reported [1,2]. Therefore, chemotherapy with DOX is limited by its cardiotoxicity. The ...
Print Publication - University of Toronto
Print Publication - University of Toronto

... acute myocardial infarction) study showed that despite an average first door-to-device time delay of ≈110 minutes, a reperfusion strategy involving the transfer of patients with STEMI from a non–PCI-capable hospital to a PCI-capable hospital for primary PCI was superior to the use of fibrinolysis at ...
Short-Acting Я-Adrenergic Antagonist Esmolol Given at
Short-Acting Я-Adrenergic Antagonist Esmolol Given at

... opened via median sternotomy and the heart suspended in a pericardial cradle. The left stellate ganglion was isolated for placement of stimulating electrodes. Catheters were placed in the descending aorta and into the coronary sinus (CS) for blood sampling. High-fidelity pressure transducers were in ...
Intravenous magnesium for cardiac arrhythmias: jack of all trades
Intravenous magnesium for cardiac arrhythmias: jack of all trades

... effects, intravenous magnesium has been reported to be effective in the prevention and treatment of a variety of cardiac arrhythmias (table 1). Intravenous magnesium is useful in preventing atrial fibrillation and ventricular arrhythmias after cardiac and thoracic surgery [20, 21], reducing the vent ...
The spectrum and distribution of imaging findings at coronary
The spectrum and distribution of imaging findings at coronary

... How can primary prevention be thus achieved? The answer may lie in evaluating and identifying the supposedly „low risk‟ group for further evaluation. The presumably „low cardiovascular risk‟ group is the target population for atherosclerosis imaging which has been proposed as a strategy for the earl ...
Integrated analysis of atrioventricular interactions in - AJP
Integrated analysis of atrioventricular interactions in - AJP

... plex adaptive response of the RV to chronic overload in TOF have provided evidence that the RV cannot be seen as one entity. In addition, the impact of RV dysfunction on left ventricular (LV) and atrial function must be considered (1, 12, 15, 26). In 1974, Suga (25) highlighted the role of the atria ...
The effect of myocardial fibrosis on left ventricular torsion
The effect of myocardial fibrosis on left ventricular torsion

... fraction (EF) were measured, conventional tissue Doppler imaging data was acquired. Speckle tracking imaging was performed to measure LV deformation, LV rotational parameters. Blood samples were obtained for NT-proBNP. Late gadolinium enhanced cardiac magnetic resonance (LGE-CMR) was used to assess ...
Role of PET/ CT for the Identification of Cardiac Sarcoid Disease
Role of PET/ CT for the Identification of Cardiac Sarcoid Disease

... dle-aged adults(11,12) . Such middle-aged patients ...
Induction of cardiac muscle differentiation in isolated
Induction of cardiac muscle differentiation in isolated

... from a range of developmental stages from neurula stage onwards to assess when the MHCα gene was activated during embryogenesis. Since the developing heart of the tadpole comprises only a small percentage of tissue when compared with the axial muscle of the myotomes, we dissected ventral and dorsal ...
Heart Rate Variability in Athletes
Heart Rate Variability in Athletes

... Other adjustments take place in almost every organ system of the body and involve all aspects of cardiac and peripheral vascular control, including regulation by the autonomic nervous system (ANS). Neural mechanisms appear to be of great importance in mediating the initial response to exercise, whic ...
Epidemiology of Coronary Artery Disease
Epidemiology of Coronary Artery Disease

... of death based upon clinical impression. This contrasts to the more objective assignment of a cause of death from formally conducted autopsy studies. Since non-forensic national autopsy rates are about 5% in most industrialised countries, the cause of death derived from these registries may be unrel ...
The Use of Digoxin in Patients With Worsening Chronic Heart Failure
The Use of Digoxin in Patients With Worsening Chronic Heart Failure

... Groningen, the Netherlands; and Chicago, Illinois Digoxin is the oldest cardiac drug still in contemporary use, yet its role in the management of patients with heart failure (HF) remains controversial. A purified cardiac glycoside derived from the foxglove plant, digoxin increases ejection fraction, ...
Transcatheter occlusion of left atrial appendage for stroke
Transcatheter occlusion of left atrial appendage for stroke

... Cardiac emboli in patients with atrial fibrillation are one of the major causes of ischemic stroke. Because the vast majority of these cardiac emboli descend from the left atrial appendage (LAA), the therapeutic strategy of percutaneous transcatheter occlusion of the LAA by means of a mechanical imp ...
Basic ECG Rhythm Identification Part II Learning Objectives
Basic ECG Rhythm Identification Part II Learning Objectives

... fire when the prevailing sinus rate becomes too low (or lower than the rate of the second-order pacemaker cells) • Sinus bradycardia combined with enhanced automaticity of the subordinate site is the common pathophysiology. ...
Pulmonary atresia with intact ventricular septum
Pulmonary atresia with intact ventricular septum

... thanks to a persistent ductus arteriosus, but such cases are extremely rare (Robicsek et al. 1966). The history of congenital heart surgery Cardiac surgery is an accomplishment of the twentieth century. The first reported successful case of cardiac surgery was the ligation of a patent ductus arterio ...
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Cardiac surgery



Cardiovascular (heart) surgery is surgery on the heart or great vessels performed by cardiac surgeons. Frequently, it is done to treat complications of ischemic heart disease (for example, coronary artery bypass grafting), correct congenital heart disease, or treat valvular heart disease from various causes including endocarditis, rheumatic heart disease and atherosclerosis. It also includes heart transplantation.
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