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The Role of TNFa and Sphingolipid Signaling in Cardiac Hypoxia
The Role of TNFa and Sphingolipid Signaling in Cardiac Hypoxia

... Figure 3. Sphingosine is released from hypoxic cardiomyocytes. Adult cardiomyocytes were cultured under either normoxia or hypoxia conditions for 5 hours. The cell-conditioned Tyrode’s solution was collected and the cells were scraped from the culture dish. Both cellular and extracellular sphingolip ...
What radiologists need to know about the pulmonary--
What radiologists need to know about the pulmonary--

... expiration. The error is considerably greater in inspiration. It is recommended that the acquisition is made with the patient breathing freely18 training them how to make soft, constant respiratory exchanges without sudden move, deep inhalations or coughing. The contrast phase sequence is usually pl ...
Role of Inflammation in Initiation and Perpetuation of Atrial
Role of Inflammation in Initiation and Perpetuation of Atrial

Circa- and ultradians in the occurrence of simple extrasystoles in
Circa- and ultradians in the occurrence of simple extrasystoles in

... The primary 24-hour Holter ECG monitoring (Premier IV Diagnostic Monitoring or Memoport C Hellige) in the precordial DAJ leads had been evaluated by a cardiologist who had not been included in statistical processing of the obtained primary data at that time. The originally observed data (1,066 supra ...
Paper Title (use style: paper title)
Paper Title (use style: paper title)

... results have been achieved in classification of current density vector maps, including classification, based on clusters analysis for coronary artery disease and ischemic heart disease detection [10], [11]. Nevertheless, classification of MCG data, especially CDDMs is on its early stage. Aim of the ...
Document
Document

... underlying heart problem.  An electric shock is needed to correct the problem in more than two thirds of all cardiac arrests. This shock is known as defibrillation.  Defibrillation is not intended to start a heart, on without electrical activity. ...
Indian Pacing and Electrophysiology Journal - Antzelevitch
Indian Pacing and Electrophysiology Journal - Antzelevitch

... in IVRT and DT, followed by LV systolic dysfunction which appeared at 6 months with an increase in LV-PEP and LV-PEP/LV-ET ratio. The reduction in LVEF also manifest at 6 months without change in the resting cardiac output. Our findings suggest two inter-related sequence of events. Firstly, it appea ...
Iatrogenic Pericardial Effusion and Tamponade in the Percutaneous
Iatrogenic Pericardial Effusion and Tamponade in the Percutaneous

... The pressure within the structure that is perforated is a major determinant of the development and severity of tamponade. Thus a small perforation of the RV in an unanticoagulated patient may not be clinically apparent; in contrast, perforation of the RV in the setting of pulmonary hypertension or a ...
Clinical Utility of Blood Natriuretic Peptide Levels
Clinical Utility of Blood Natriuretic Peptide Levels

... De Lemos et al. found that a BNP level >137.8pg/ml occurred only in 25% of ACS patients (fourth quartile), but when at this level predicted higher rates of all-cause mortality at 30-days and six months.32 Above a threshold of 80pg/ml, there were higher rates of death, new or progressive HF, and recu ...
pulmonary circulation
pulmonary circulation

... aortal & pulmonal stenosis, coarctation of aorta ...
Heart and Circulation Gestational High
Heart and Circulation Gestational High

... and salt excess (8%NaCl) led to increased left ventricular mass, myocardial fibrosis, and impairment of LV diastolic function in SHR [14]. On the other hand, cardiovascular structure and function and the risk of developing cardiovascular disease are also influenced by the maternal environment during ...
Acute colchicine intoxication complicated with complete AV block
Acute colchicine intoxication complicated with complete AV block

... Colchicine, is an old and well-known drug, used for treatment of rheumatic diseases. Nausea, vomiting, abdominal pain, and diarrhea are the clinical symptoms of colchicine poisoning. Cardiotoxicity can lead to mortality. We report a case of colchicine intoxication complicated with complete heart blo ...
Clinical significance of cardiac murmurs: Get the sound and rhythm
Clinical significance of cardiac murmurs: Get the sound and rhythm

... valve area, radiating dorsally with an intensity varying between 1/6 and 5/6. The backflow of blood into the left atrium results in an increased atrial filling with more blood flow during early ventricular filling often producing a louder third heart sound. Increased atrial pressures impede pulmonar ...
tipos de sangue
tipos de sangue

... irrigated. Harvey characterized blood pulsation as the result of the arteries filling with arterial blood during each heart contraction. He demonstrated that the arterial blood left the heart by contraction of the left ventricle, which happened simultaneously with contraction of the right ventricle ...
Bundle-Branch Block
Bundle-Branch Block

... plane in persons with right and left ventricular hypertrophy.8 From theoretic approaches he also coneluded that the electrocardiographic diagnosis at that time of right and left bundle-branch block was reversed. In the diagnosis of congenital defects, the information contributed by the electrocardio ...
glucocorticoids activate cardiac mineralocorticoid receptors in
glucocorticoids activate cardiac mineralocorticoid receptors in

... aldosterone on the cardiovascular system include the induction of hypertrophy and fibrosis, a reduction in vascular compliance, ventricular diastolic dysfunction, and ventricular arrhythmia.1, 2) Transgenic mice with a selective increase in the activity of mineralocorticoid receptors (MRs) in cardia ...
Self Assessment CME Treatment of Aortic Valve Stenosis
Self Assessment CME Treatment of Aortic Valve Stenosis

... I No limitation of physical activity. Ordinary physical activity does not cause undue fatigue, palpitation, dyspnea (shortness of breath). II Slight limitation of physical activity. Comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea (shortness of breath). III Ma ...
Forearm Blood Flow In Individuals With CHF And Age
Forearm Blood Flow In Individuals With CHF And Age

... deliver. CHF is a life threatening condition that increases in prevalence with aging and is associated with high mortality (50% at 5 yrs from diagnosis). Currently, there are estimated to be five million Americans living with heart failure and approximately 500,000 new cases each year. It is the mos ...
January 2014
January 2014

... tongue in the back of the pharynx  blocks the ability of the palatal shelves to fuse properly severe respiratory distress: mortality rate as high as 30% careful monitoring: first 1 to 4 weeks over time, the lower jaw generally “catches up” in growth vs. surgical intervention (jaw expansion) isolate ...
Four-Chamber Heart Modeling and Automatic
Four-Chamber Heart Modeling and Automatic

... Two topics are discussed: heart modeling and automatic model fitting to an unseen volume. Heart modeling is a non-trivial task since the heart is a complex nonrigid organ. The model must be anatomically accurate, allow manual editing, and provide sufficient information to guide automatic detection a ...
A neural explanation of fetal heart rate patterns: A test of the
A neural explanation of fetal heart rate patterns: A test of the

... reptiles, the dorsal motor vagal system is the predominant vagal system in the regulation of cardiopulmonary processes. This system promotes apnea and bradycardia by constricting the bronchi and by inhibiting the cardiac pacemaker. These physiological responses are neurophysiologically consistent wi ...
Aortic Aneurysm Guide
Aortic Aneurysm Guide

... A blood clot may also form in the aneurysm. Small pieces of a blood clot can break off and travel throughout the body. If a fraction of a clot gets stuck in a brain or heart blood vessel, it can cause stroke or heart attack. In other vital organs, like the kidneys or liver, a piece of blood clot can ...
Allschwil, 8 September 2005
Allschwil, 8 September 2005

... Lankhaar J-W et al. European Heart Journal (2008)29,1688-1695 ...
Left atrial strain in patients with arterial hypertension
Left atrial strain in patients with arterial hypertension

... extensive clinical and laboratory examinations; more than mild valve disease; overt coronary artery disease (defined by at least one of the following: history of effort angina, acute coronary syndrome or revascularization procedures; positive exercise stress test; segmental wall motion abnormalities ...
Coil occlusion of systemic venous collaterals in - Heart
Coil occlusion of systemic venous collaterals in - Heart

... left atrium and the other to the IVC. These were occluded with a 5 × 4 and a 5 × 5 coil, respectively. The last child had a meshwork of collaterals arising from the innominate vein draining to both atria and the IVC; these were occluded at their origin with three coils: one 5 × 5 and two 3 × 4. Repe ...
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Myocardial infarction



Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.
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