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Lecture 9 th ​, 10 th week
Lecture 9 th ​, 10 th week

... - Preload is related with the volume of blood entering the chamber (EDV) - Depends from EDV, EDP, Left atrium pressure, Pulmonary veins pressure Afterload: The load against which a myocyte must shorten - The principal component of afterload is arterial pressure - depends from pressure in aorta, tota ...
Complex Relationship Between Blood Pressure and
Complex Relationship Between Blood Pressure and

... Considering the accelerated arterial stiffening in type 2 diabetes,22 it seems plausible that the elevated mortality observed in the highest PP categories would be linked to increased arterial stiffness and, thus, reflect arterial ageing. In addition to being a marker of poor vascular health, arteri ...
Quantification of the Contribution of Cardiac and Arterial - VU-dare
Quantification of the Contribution of Cardiac and Arterial - VU-dare

... and in the intact mammal.23,24 Randall et al23 concluded that compliance changes alone do not lead to (isolated systolic) hypertension. Kelly et al24 found a 47% increase in SBP after lowering compliance by 60% to 80%, but in their study, peripheral resistance (⫹17%) and venous filling pressure (⫹38 ...
Lecture 3 LRC
Lecture 3 LRC

... Low-density lipoprotein (LDL): cause atherosclerosis. Optimal levels are less than 100 mg/dL. 160-189mg/dL are considered high High-density lipoproteins (HDL): help rid the body of LDLs. High levels of HDLs prevent CAD. Triglycerides: another form of fat found in the bloodstream. Increased levels of ...
Degenerative Valve Disease Explained - New
Degenerative Valve Disease Explained - New

... medications is essential to survival. There are several drugs that can help to relieve clinical signs of degenerative valve disease. The cardiologist may prescribe diuretics (frusemide) to help reabsorb fluid from the lungs. Other medications that increase survival time once congestive heart failure ...
beta-blockers: Are they useful in arrhythmias?
beta-blockers: Are they useful in arrhythmias?

... patients with ventricular arrhythmias. Beta-blockers increase the threshold for VF during acute ischaemia and a decrease in VF was demonstrated in some placebo-controlled trials with metoprolol, atenolol and propranolol very early after onset of symptoms. 7,13 After acute myocardial infarction, the ...
Understanding Stroke Risk and Treatment
Understanding Stroke Risk and Treatment



... The mucus, lining the stomach protects the wall from being damaged by the acid ( pH 2). Acid provides the correct pH for the protein digesting enzyme pepsin to work. ...
Heart Last modified January 9, 2017 at 5:21 am
Heart Last modified January 9, 2017 at 5:21 am

... B) The atrial blood is flowing backward and causing the extra sound. C) The atrioventricular valves are not closing at the same time. D) The AV and semilunar valves are not closing at the same time. E) No such double sound has ever been heard. Question # 6 The aorta leaves the ...
Blood vessels
Blood vessels

... Aspirin reduces the stickiness of platelets and reduces clot formation and lowers the risk of heart attack. ...
Systems Physiology Quiz F2004
Systems Physiology Quiz F2004

... Monday, October 11, 2004 ...
The Heart - The Dublin School of Grinds
The Heart - The Dublin School of Grinds

... 3) Right ventricle contracts pumping blood out through the pulmonary artery to the lungs. 4) Blood gains oxygen at the lungs and loses carbon dioxide. 5) The now oxygenated blood (high levels of oxygen) enters the left atrium through the pulmonary vein. ...
CARDIOVASCULAR SYSTEM –THE HEART CIRCULATION The
CARDIOVASCULAR SYSTEM –THE HEART CIRCULATION The

... 1. The Atria or the auricles are the upper or superior chambers of the heart. This chamber is divided into a left and right auricle by the inter auricular septum. The auricles are thinwalled as they only receive blood brought in by the veins and send it to the ventricles. 2. The Ventricles are the l ...
packetonheart
packetonheart

... A heart murmur can be a sign of a health problem when there is a hole between two parts of the heart and the blood is coming from two directions at once, mixing together and causing turbulence and you can hear it. This type of heart murmur may be a problem. It depends on how much blood is going in t ...
STAT 510 Homework 11 Due Date: 11:00 A.M., Wednesday, April 19
STAT 510 Homework 11 Due Date: 11:00 A.M., Wednesday, April 19

... (b) Without the aid of a computer, find the value of P W y. Note that it is usually easiest to compute this by finding (W 0 W )−1 , W 0 y, (W 0 W )−1 W 0 y, and then finally W (W 0 W )−1 W 0 y. Even though you don’t have all the elements of y it is still possible to compute P W y from the averages i ...
Core Clinical Problem 52: Murmur Summary ΔΔ (Index Conditions
Core Clinical Problem 52: Murmur Summary ΔΔ (Index Conditions

...  ECG: normal in small; large shows biventricular hypertrophy and pulmonary hypertension (T wave upright, if inversted suggests no PH)  Echocardiogram: assess anatomy and haemodynamic effects with doppler Management Small lesions mostly close spontaneously. Promote good dental hygiene; prophylactic ...
Management
Management

... “ A 72 year old lady presents with a history of increasing SOB, orthoponea and palpitations over a few months. She has a history of Angina, Hypertension. She is found to be in Atrial fibrillation” ...
ARVD Program Brochure
ARVD Program Brochure

... by blocking the effects of adrenaline or improving blood flow to the heart. Beta blockers lower the heart rate, blood pressure, and the effects of adrenaline, which seems to play a role in causing arrhythmias. Beta blockers are a safe and commonly used type of medica ...
HOPE - New England Journal of Medicine
HOPE - New England Journal of Medicine

... account for the risk. Therefore, other risk factors must be identified in order to reduce mortality and morbidity even further. Epidemiologic and experimental data suggest that activation of the renin– angiotensin–aldosterone system has an important role in increasing the risk of cardiovascular even ...
Effect of Atenolol on Left Ventricular Function in
Effect of Atenolol on Left Ventricular Function in

... demonstrated less frequently in man and then only in acute intravenous experiments (Robinson, Jackson, Fisk & Jewitt, 1978). Information regarding its effect on left ventricular function after oral therapy have not been reported. The purpose of this work was to study the effects of oral atenolol the ...
dysrhythmics
dysrhythmics

... states of the channel (i.e. open, closed, or inactivated). Two current models: a. modulated receptor hypothesis: different states have different affinities b. guarded receptor hypothesis: channel gate limits drug access to site b. Dysrhythmic drugs selectively affect firing and CV in abnormal/depola ...
the pregnant patient with pulmonary artery hypertension
the pregnant patient with pulmonary artery hypertension

... relief of inferior vena cave pressure cause large fluid shifts to the maternal circulation. Right ventricular volume overload can occur easily. Pregnancy is associated with a hypercoagulable state due to increased fibrin levels, reduced fibrinolytic activity, increased procoagulant activity with hig ...
Document
Document

... • Therefore, it suggests that the same risk factors that predispose to coronary artery disease may also predispose to aortic stenosis. • Mitral valve prolapse • It is a common condition, but only a few develop problems ...
lily of the valley
lily of the valley

... Indications: arrhythmia, congestive heart failure, oedema of cardiac origin, cardiac asthma. Therapeutics and Pharmacology: Convallaria is a valuable heart remedy with an action similar to Digitalis but without its potential toxic effects. It increases myocardial efficiency and stroke volume without ...
The Heart and Blood Vessels
The Heart and Blood Vessels

... The heart then rests for a short time (diastole). Blood coming back to the heart from the large veins fills the atria during diastole: The veins coming into the left atrium are from the lungs (full of oxygen). The veins coming into the right atrium are from the rest of the body (depleted of oxygen). ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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