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the MADIT-CRT Trial Slides
the MADIT-CRT Trial Slides

... environments that could adversely affect the operation of the active implantable medical device, including areas protected by a warning notice that prevents entry by patients who have a pulse generator. Do not expose a patient to MRI device scanning. Strong magnetic fields may damage the device and ...
Diastolic Heart Failure Is A Cardiac Problem-Debate - sha
Diastolic Heart Failure Is A Cardiac Problem-Debate - sha

... defined as an LVEF ≥ 40%, ≥45%, or ≥ 50%. • When these patients have invasive or non‐invasive evidence of  abnormal diastolic function (either abnormal relaxation, filling or  stiffness) they are said to have ‘‘diastolic HF’ Gaasch WH. Diagnosis and treatment of heart failure based on left ventricul ...
Scaling of Cardiovascular Physiology in Snakes1
Scaling of Cardiovascular Physiology in Snakes1

... level just anterior to the cloaca. The cathBody mass, body length and heart posi- eter was fashioned from polyethylene tubtion were measured in 412 snakes of 95 ing of appropriate size and was filled with species. Most specimens were fresh but heparinized (250 i.u./ml) saline. After a some were pres ...
Beneficial Neurohormonal Profile of Spironolactone in
Beneficial Neurohormonal Profile of Spironolactone in

... Increased levels of norepinephrine (NE) and natriuretic peptides, such as atrial natriuretic peptide and brain natriuretic peptide (BNP), as well as activation of the reninangiotensin-aldosterone system (RAAS), have been described and associated with a poor prognosis (2,3). Aldosterone promotes the ...
- Medicexchange
- Medicexchange

... environments that could adversely affect the operation of the active implantable medical device, including areas protected by a warning notice that prevents entry by patients who have a pulse generator. Do not expose a patient to MRI device scanning. Strong magnetic fields may damage the device and ...
Practical Electrocardiography: Diagnosis, Interpretation and
Practical Electrocardiography: Diagnosis, Interpretation and

... may be differentiated from a sinus tachycardia by the abruptness at which it starts up and turns off (sinus tachycardias should be more gradual). There is also a slightly different appearance to the P wave, if it is present. Ectopic Atrial Tachycardia This is an uncommon tachyarrhythmia defined by a ...
Left ventricular diastolic dysfunction
Left ventricular diastolic dysfunction

... determinant of diastolic filling. Tachycardia is poorly tolerated. Beta blockers and calcium channel blockers improve diastolic filling Patients with diastolic dysfunction may be on angiotensin receptor blockers as they are known to reduce LV hypertrophy and lead to improved LV filling through after ...
Tricuspid annular plane systolic excursion and - AJP
Tricuspid annular plane systolic excursion and - AJP

... placed on ice and centrifuged at 4°C. Plasma samples were stored at ⫺20°C until assay. The time between NT-pro-BNP and echo measurements was 4 ⫾ 3 days. ...
Point:Counterpoint: Respiratory sinus arrhythmia is due to a central
Point:Counterpoint: Respiratory sinus arrhythmia is due to a central

... COUNTERPOINT: RESPIRATORY SINUS ARRHYTHMIA IS DUE TO THE BAROREFLEX MECHANISM ...
Effect of Erythropoietin on Exercise Capacity in Patients With
Effect of Erythropoietin on Exercise Capacity in Patients With

... Anemia is common in elderly patients with CHF and increases with disease severity.2,11,12 Anemia in CHF is frequently untreated, however, despite previous reports that anemia can contribute to the worsening of CHF.13 Recent analysis of the Studies Of Left Ventricular Dysfunction (SOLVD) database sho ...
Common types of congenital heart defects
Common types of congenital heart defects

... distinct pulmonary artery and aorta merge into one single great vessel (truncus) arising from the right and left ventricles. In addition, there's usually a large ventricular septal defect, essentially turning the right and left ventricles into a single chamber. This allows oxygenated and unoxygenate ...
A Patient`s Guide to the Non-surgical Closure of an Atrial Septal Defect
A Patient`s Guide to the Non-surgical Closure of an Atrial Septal Defect

... of ASDs are in the ostium secundum.1 – Non-surgical closure (using a transcatheter device) of ASDs only benefits patients with centrally located ostium secundum ASDs.1,4 ...
1 Gender and Posture Differences in Cardiovascular Responses to
1 Gender and Posture Differences in Cardiovascular Responses to

... norepinephrine, epinephrine, and dopamine were greater in men at the first minute of exercise. Of these three catecholamines, epinephrine concentration specifically was significantly greater in men at the first minute of exercise. If the concentration were high enough this could account for the sign ...
Planning, COPD Hot Topics and CSA Preparation
Planning, COPD Hot Topics and CSA Preparation

... • Over 4 years, patients consitently reported a better QOL • Significantly delays time to first exacerbation ...
P Gokal Whats in the pipeline
P Gokal Whats in the pipeline

... is less useful in clinical medicine as there is no one diagnostic test to quantify blood volume. Generally speaking it is a state in which a patient has hypoperfusion, which will improve with fluid therapy. In current literature, hypovolaemia is most often defined as, the shocked patient in whom str ...
The Circulatory System: Heart
The Circulatory System: Heart

... – Not a cure for artery disease, but may allow time for other corrective action ...
N-terminal Pro-brain Natriuretic Peptide as a Prognostic Predictor in
N-terminal Pro-brain Natriuretic Peptide as a Prognostic Predictor in

... Background: This study evaluated plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) as a potential prognostic predictor in critical care patients with acute cardiogenic pulmonary edema within 24 hours after admission. Methods: Fifty patients with acute cardiogenic pulmonary edema admitted t ...
Angina Patients With Diastolic Versus Systolic Heart Failure
Angina Patients With Diastolic Versus Systolic Heart Failure

... versus diastolic dysfunction was 1.89 (95% confidence interval 1.03–3.38) when corrected for age, gender, prior myocardial infarction, hypertension, and non–cardiac vascular disease. A similar model for MACE demonstrated no significant difference between the 2 groups when corrected for the baseline ...
N Engl J Med
N Engl J Med

... SCD-HeFT: Conclusions In class II or III CHF patients with EF < 35% on good background drug therapy, the mortality rate for placebo-controlled patients is 7.2% per year over 5 years  Simple, shock-only ICDs decrease mortality by 23%  Amiodarone, when used as a primary preventive agent, does not i ...
TEST 2 CARDIAC CONDITIONS
TEST 2 CARDIAC CONDITIONS

... Systolic Pressure: the force exerted against the arterial wall w/ ventricular contraction (cardiac output & volume) Diastolic pressure: force exerted against the arterial wall when the heart is relaxed (peripheral vascular resistance). Pulse pressure = systolic - diastolic pressure ...
asians at higher risk for heart failure
asians at higher risk for heart failure

... Diabetic patients are also strongly encouraged to quit smoking if they have the habit. Smoking is a major risk factor for heart disease and it increases the risk of lung complications after CABG in addition to disrupting wound healing. Hence, smoking cessation is essential in improving the long-term ...
Folic Acid Deficiency in Congestive Heart Failure - Heart
Folic Acid Deficiency in Congestive Heart Failure - Heart

... retention were increased in Case 7. Xylose excretion tests were performed on 11 patients; abnormally low values were detected in 7. In contrast, the 10 Schilling tests done were all within normal limits. The 5'Cr red cell survival was shortened in 4 of 10 instances (Cases 2, 6, 7, and 10) in which t ...
3
3

... zero. And since muscle length is presumably increased in PAH patients in case of eccentric remodelling, this patient category will have higher V0-values compared to persons with non-dilated ventricles. The theory above suggests a positive relation between ventricular volume and V 0. This relationshi ...
Coronary Artery Disease Angina Acute Coronary Syndrome
Coronary Artery Disease Angina Acute Coronary Syndrome

... through phases, caused by injury to intima of artery – Progression of CAD • Phase I : fatty streaks – do not obstruct flow ...
cardiac education for our community
cardiac education for our community

... describe a process where by the heart can’t pump enough blood to meet the demands of the body’s organs. Underlying conditions which can contribute to congestive heart failure include coronary artery disease (narrowed vessels that supply blood to the heart muscle), previous heart attacks, hypertensio ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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