Clinical Signs of Acute Pericarditis and Its
... Southwestern Medical Center, Dallas, TX. Dr. Karnath is an associate professor of medicine, Division of General Medicine, University of Texas Medical Branch, Galveston, TX. ...
... Southwestern Medical Center, Dallas, TX. Dr. Karnath is an associate professor of medicine, Division of General Medicine, University of Texas Medical Branch, Galveston, TX. ...
Percutaneous Left Atrial Appendage Closure Devices for Stroke
... these trials. Relevant outcomes are overall survival, morbid events, and treatment-related morbidity. The most relevant evidence comes from two industry-sponsored RCTs that compared the Watchman device with anticoagulation. One trial reported noninferiority on a composite outcome of stroke, cardiova ...
... these trials. Relevant outcomes are overall survival, morbid events, and treatment-related morbidity. The most relevant evidence comes from two industry-sponsored RCTs that compared the Watchman device with anticoagulation. One trial reported noninferiority on a composite outcome of stroke, cardiova ...
Differences in Sarcoplasmic Reticulum Ca2+ Leak Characteristics
... colleagues (26) have been the primary proponents of the idea that SR Ca2+ leak may be increased by RyR2 hyperphosphorylation for 10 years. They showed that phosphorylation by either protein PKA or CaMKII might increase RyR2 phosphorylation status and activity (26, 41, 42). RyR2 hyperphosphorylation ...
... colleagues (26) have been the primary proponents of the idea that SR Ca2+ leak may be increased by RyR2 hyperphosphorylation for 10 years. They showed that phosphorylation by either protein PKA or CaMKII might increase RyR2 phosphorylation status and activity (26, 41, 42). RyR2 hyperphosphorylation ...
Cardiovascular Responses to Exercise
... stimulation. Thus, changes in stroke volume occur because left ventricular end–diastolic volume increases and left ventricular end–systolic volume decreases (Poliner, et al., 1980). Left ventricular end–diastolic volume increases because of the return of blood to the heart by the active muscle pump, ...
... stimulation. Thus, changes in stroke volume occur because left ventricular end–diastolic volume increases and left ventricular end–systolic volume decreases (Poliner, et al., 1980). Left ventricular end–diastolic volume increases because of the return of blood to the heart by the active muscle pump, ...
American College of Cardiology Foundation, American Heart Association Task
... It is essential that the medical profession play a central role in critically evaluating the evidence related to drugs, devices, and procedures for the detection, management, or prevention of disease. Properly applied, rigorous, expert analysis of the available data documenting absolute and relative ...
... It is essential that the medical profession play a central role in critically evaluating the evidence related to drugs, devices, and procedures for the detection, management, or prevention of disease. Properly applied, rigorous, expert analysis of the available data documenting absolute and relative ...
... Background: Up-regulation of HO-1 by genetic manipulation or pharmacological pre-treatment has been reported to provide benefits in several animal models of myocardial infarction (MI). However, its efficacy following MI initiation (as in clinical reality) remains to be tested. Therefore, this study ...
Syncope - Royal College of Emergency Medicine
... syncope with sensitivity of 95% and specificity of 45%. If the patient does not have evidence of heart disease (normal examination and ECG) then a cardiac cause of syncope is ruled out 97% of the time. This group should be further evaluated in the ED on a monitored bed. IP referral is suggested by P ...
... syncope with sensitivity of 95% and specificity of 45%. If the patient does not have evidence of heart disease (normal examination and ECG) then a cardiac cause of syncope is ruled out 97% of the time. This group should be further evaluated in the ED on a monitored bed. IP referral is suggested by P ...
Cardiovascular Phenotype in Turner Syndrome—Integrating
... highly unfortunate because morbidity and mortality are a great deal higher than in the general population (1, 3, 4). Additionally, clinical assessment is poor even in diagnosed individuals (5), although multidisciplinary practice may improve this (6). Therefore, both appropriate identification of gi ...
... highly unfortunate because morbidity and mortality are a great deal higher than in the general population (1, 3, 4). Additionally, clinical assessment is poor even in diagnosed individuals (5), although multidisciplinary practice may improve this (6). Therefore, both appropriate identification of gi ...
What is hypertrophic cardiomyopathy (HCM)?
... The heart (specifically the left ventricle) may also thicken in other individuals who do not have HCM, either as a result of high blood pressure, obstructive heart valve disease, or even prolonged and intense athletic training in certain sports. The type of hypertrophy associated with high blood pre ...
... The heart (specifically the left ventricle) may also thicken in other individuals who do not have HCM, either as a result of high blood pressure, obstructive heart valve disease, or even prolonged and intense athletic training in certain sports. The type of hypertrophy associated with high blood pre ...
Management of cardiogenic shock complicating acute myocardial
... days, one year and six years for CABG compared with PCI in patients with cardiogenic shock, despite a longer time from symptom onset to revascularization and a greater prevalence of diabetes mellitus, left main disease and threevessel disease among patients undergoing CABG.37 In a recent registry, t ...
... days, one year and six years for CABG compared with PCI in patients with cardiogenic shock, despite a longer time from symptom onset to revascularization and a greater prevalence of diabetes mellitus, left main disease and threevessel disease among patients undergoing CABG.37 In a recent registry, t ...
Best practice in the clinical management of atrial fibrillation in
... 5-6x increased annual risk of stroke4 14% of all strokes = 12,500 strokes a year2 strokes of generally greater severity, mortality and morbidity resulting in more lengthy hospital stays compared with strokes occurring in people without AF 2,4 6,000 strokes that could be prevented if patients were ad ...
... 5-6x increased annual risk of stroke4 14% of all strokes = 12,500 strokes a year2 strokes of generally greater severity, mortality and morbidity resulting in more lengthy hospital stays compared with strokes occurring in people without AF 2,4 6,000 strokes that could be prevented if patients were ad ...
Sleep apnoea as an independent risk factor
... mortality increased only in patients with untreated severe OSAS, whereas simple snorers, OSAS patients with mild disease or patients with severe OSAS who accepted CPAP treatment showed morbidity and mortality figures very similar to those obtained in the general population. The study by DOHERTY et a ...
... mortality increased only in patients with untreated severe OSAS, whereas simple snorers, OSAS patients with mild disease or patients with severe OSAS who accepted CPAP treatment showed morbidity and mortality figures very similar to those obtained in the general population. The study by DOHERTY et a ...
Composition of the Blood, cont.
... Pretest True or False 1. The pointed end of the heart is the apex. 2. The myocardium forms the bulk of the heart wall. 3. The coronary arteries branch off the aorta to supply the heart with oxygen and nutrients. 4. The SA node is located in the right atrium. 5. The adult male has 5-6 liters of bloo ...
... Pretest True or False 1. The pointed end of the heart is the apex. 2. The myocardium forms the bulk of the heart wall. 3. The coronary arteries branch off the aorta to supply the heart with oxygen and nutrients. 4. The SA node is located in the right atrium. 5. The adult male has 5-6 liters of bloo ...
Clinical recommendations for cardiopulmonary exercise testing data
... must be performed manually at this time. Given the importance of determining EOV in heart failure (HF), the writing group anticipates that the presence or absence of this abnormality, according to universally adopted criteria, will be automatically quantified by future CPX system software packages. ...
... must be performed manually at this time. Given the importance of determining EOV in heart failure (HF), the writing group anticipates that the presence or absence of this abnormality, according to universally adopted criteria, will be automatically quantified by future CPX system software packages. ...
Digitalis Toxicity: A Fading but Crucial Complication to Recognize
... an antiquated practice of titrating doses until toxic manifestations arose, to a lower dosing regimen guided by serum levels. Digoxin continues to play a role in treatment of chronic systolic/diastolic heart failure and atrial fibrillation. However, due to several landmark studies showing physiologi ...
... an antiquated practice of titrating doses until toxic manifestations arose, to a lower dosing regimen guided by serum levels. Digoxin continues to play a role in treatment of chronic systolic/diastolic heart failure and atrial fibrillation. However, due to several landmark studies showing physiologi ...
Digitalis Toxicity: A Fading but Crucial Complication to Recognize REVIEW
... an antiquated practice of titrating doses until toxic manifestations arose, to a lower dosing regimen guided by serum levels. Digoxin continues to play a role in treatment of chronic systolic/diastolic heart failure and atrial fibrillation. However, due to several landmark studies showing physiologi ...
... an antiquated practice of titrating doses until toxic manifestations arose, to a lower dosing regimen guided by serum levels. Digoxin continues to play a role in treatment of chronic systolic/diastolic heart failure and atrial fibrillation. However, due to several landmark studies showing physiologi ...
Percutaneous closure should be performed in all
... in any patient with PFO and cryptogenic stroke categorically indicates that, from the point of view of the guidelines and medical consensus, a class I recommendation should apply (should, it is recommended, it has been indicated, it is useful, or effective, or beneficial). Such recommendati ...
... in any patient with PFO and cryptogenic stroke categorically indicates that, from the point of view of the guidelines and medical consensus, a class I recommendation should apply (should, it is recommended, it has been indicated, it is useful, or effective, or beneficial). Such recommendati ...
SessionProgramme 14 April - Scientific Events
... F Ruschitzka (Zurich, CH)(OK) - D J van Veldhuisen (Groningen, NL)(OK) ...
... F Ruschitzka (Zurich, CH)(OK) - D J van Veldhuisen (Groningen, NL)(OK) ...
Matching dicrotic notch and mean pulmonary artery - AJP
... diagnostic right and left heart catheterization for the investigation of chest pain, heart failure, or other cardiovascular disorders. Patients with rhythm disturbances and valve disease were excluded from the study. In one case, dicrotic notch pressure could not be clearly identified in the pulmona ...
... diagnostic right and left heart catheterization for the investigation of chest pain, heart failure, or other cardiovascular disorders. Patients with rhythm disturbances and valve disease were excluded from the study. In one case, dicrotic notch pressure could not be clearly identified in the pulmona ...
Impact of Definitions of Left Ventricular Hypertrophy on Left
... partition values. Partition values for LVM normalized for body surface area (BSA) were 116 g/m2 for men and 104 g/m2 for women.4 Partition values for LVM indexed for height were 126 g/m for men and 105 g/m for women.5 Partition values for LVM indexed for the height allometric growth rate of 2.7 (HT2 ...
... partition values. Partition values for LVM normalized for body surface area (BSA) were 116 g/m2 for men and 104 g/m2 for women.4 Partition values for LVM indexed for height were 126 g/m for men and 105 g/m for women.5 Partition values for LVM indexed for the height allometric growth rate of 2.7 (HT2 ...
Pulmonary Venous and Arterial Hypertension due
... adhesions and return blood to the right heart. This collateral system is capable of carrying up to 20% of the flow of an unobstructed lung. A significant shunt (left-to-right) is ruled out in this case by the normal contour of the indicator-dilution studies following inferior caval and proximal pulm ...
... adhesions and return blood to the right heart. This collateral system is capable of carrying up to 20% of the flow of an unobstructed lung. A significant shunt (left-to-right) is ruled out in this case by the normal contour of the indicator-dilution studies following inferior caval and proximal pulm ...
7: Stable Ischemic Heart Disease - Welcome to the CardioSource
... that varies in terms of comorbidities, symptoms, and risk of future cardiovascular (CV) events. SIHD includes any condition that results in a chronic or repetitive mismatch between myocardial oxygen supply and demand. Typically, SIHD is due to atherosclerotic obstruction of the epicardial coronary a ...
... that varies in terms of comorbidities, symptoms, and risk of future cardiovascular (CV) events. SIHD includes any condition that results in a chronic or repetitive mismatch between myocardial oxygen supply and demand. Typically, SIHD is due to atherosclerotic obstruction of the epicardial coronary a ...
draft - Barnaby R. Hutchins
... things’). This is entirely consistent with Descartes’s ontological commitments, but it is not, I want to argue, the approach that Descartes takes in accounting for the ‘principal parts’ (Passions a. 6) of the body. It is the reduction to the lowest level that I argue against here: instead of reducti ...
... things’). This is entirely consistent with Descartes’s ontological commitments, but it is not, I want to argue, the approach that Descartes takes in accounting for the ‘principal parts’ (Passions a. 6) of the body. It is the reduction to the lowest level that I argue against here: instead of reducti ...
Progression of mitral regurgitation
... consequences of MR, particularly an increase in LV enddiastolic volume index (p ⬍ 0.004) and left atrial volume and a decrease in cardiac index (Table 1). The increase in systolic pulmonary artery pressure and end-systolic volume index (p ⫽ 0.31) did not reach statistical significance. The variation ...
... consequences of MR, particularly an increase in LV enddiastolic volume index (p ⬍ 0.004) and left atrial volume and a decrease in cardiac index (Table 1). The increase in systolic pulmonary artery pressure and end-systolic volume index (p ⫽ 0.31) did not reach statistical significance. The variation ...
Antihypertensive drug
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.