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Sudden Cardiac Death - Hellenic Journal of Cardiology
Sudden Cardiac Death - Hellenic Journal of Cardiology

... Introduction: The identification of high-risk patients in hypertrophic cardiomyopathy (HCM) is still a challenge. The classical clinical risk factors for sudden death have been reported by studies coming from referral HCM cohorts. So far, other studies of community-based HCM populations have not man ...
Evaluation and Management of Patients with Acute Decompensated
Evaluation and Management of Patients with Acute Decompensated

... and congestive symptoms predominate. Patients with severely impaired systolic function, reduced blood pressure, and symptoms from poor end-organ perfusion are in the distinct minority. Natural history studies have shown that ADHF represents a period of high risk for patients, during which their like ...
Contrast Induced Nephropathy - Society for Cardiovascular
Contrast Induced Nephropathy - Society for Cardiovascular

... density with iodine best. Minimum iodine concentrations are 300 mg/ml (normal range 320-400 mg/dl). Classification is based upon an agents ability to dissociate (ionic) or not dissociate (nonionic) into ionic particles when introduced into blood. ...
Evaluation of Changes In Mean Platelets Volume In Children With
Evaluation of Changes In Mean Platelets Volume In Children With

... Even though there is limited data, these patients have been reported to have a decreased survival rate [11]. Mean platelet volume (MPV) is one of the most important parameters that show thrombocyte size [5]. ...
ASD, Ostium secundum
ASD, Ostium secundum

... – May passively occur in patients with left atrial hypertension and left ventricular dysfunction, mitral valve disease and hose with aortic stenosis ...
Atrial Fibrillation: Newer Strategies in Treatment and Anticoagulation
Atrial Fibrillation: Newer Strategies in Treatment and Anticoagulation

... • Rate control (using digoxin, beta blocker, and/or calcium channel ...
Bradycardia
Bradycardia

T H E T R U T H THE HEART TRUTH
T H E T R U T H THE HEART TRUTH

... form of heart disease. Usually referred to simply as “heart disease,” it is a disorder of the blood vessels of the heart in which a waxy substance called plaque builds up in the coronary arteries. This condition is called atherosclerosis and can lead to a heart attack. A heart attack usually happens ...
Chapter_047
Chapter_047

... disease process in another body system. Primary hypertension is idiopathic. MA responsibility—two BP readings, 2 minutes apart, with patient sitting in chair; if elevated, check BP in the other arm. Chronic elevated blood pressure can result in left ventricular hypertrophy, angina, MI, heart failure ...
Echocardiography Can Identify Patients With Increased Pulmonary
Echocardiography Can Identify Patients With Increased Pulmonary

Prognostic Usefulness of Dyspnea Versus Fatigue
Prognostic Usefulness of Dyspnea Versus Fatigue

workbook - Deltex Medical
workbook - Deltex Medical

... resulting in a ≥10% increase in stroke volume (in a healthy heart and to some extent in diseased hearts) and therefore move up the Starling curve. When this rise is less than 10%, this would suggest that a further fluid challenge may not be beneficial (but it is important to consider the clinical si ...
Relationship of HMGCR gene expression and statin efficacy
Relationship of HMGCR gene expression and statin efficacy

... HDL cholesterol increased by ~22%. During the 32 mo follow-up period, the rate of clinical events was not different with niacin vs. placebo, and there was no evidence that this would change by continuing the trial (p<0.0001). There was also an excess of strokes in the niacin group. The study was ter ...
AHA Scientific Statement: Drugs That May Cause or Exacerbate
AHA Scientific Statement: Drugs That May Cause or Exacerbate

OMEGA-3 FATTY ACIDS AND - GOED Omega-3
OMEGA-3 FATTY ACIDS AND - GOED Omega-3

... blood pressure, diabetes and obesity and can be improved, this paper focuses on the contribution of dietary long-chain omega-3 polyunsaturated fatty acids (omega-3 PUFAs) to reducing the risk of CVD. Long-chain omega-3 PUFAs come primarily from seafood or marine algae and consist mainly of eicosapen ...
Pacific Coast Society of Orthodontists
Pacific Coast Society of Orthodontists

... Drug Use during Pregnancy FDA 5 Categories Category “A” Controlled human studies: no risk to fetus. “Safe” drugs (unused category: no controlled human studies for pregnancy) *Category “B” Animal studies: no risk to fetus. Routine use: no human studies showing risk to fetus. “Relatively safe” drugs: ...
To or view the full scientific statement, click here.
To or view the full scientific statement, click here.

... eart failure (HF) remains the leading discharge diagnosis among patients ≥65 years of age. The estimated cost for treatment of HF in Medicare recipients is $31 billion and is expected to increase to $53 billion by 2030.1 Hospitalization for HF is the largest segment of those costs. It is likely that ...
Obstructive sleep apnea and coronary artery disease
Obstructive sleep apnea and coronary artery disease

... persists during the day and is thought to play a key role in the association of OSA and elevated systemic blood pressure. Nowadays, OSA is accepted as an independent risk factor for arterial hypertension. Several investigations support an association of OSA with ischemic ST-segment changes, ventricu ...
Clinical Spectrum of Acute or New
Clinical Spectrum of Acute or New

... 4544 individuals with metabolic syndrome at baseline were followed-up for 4.5 years. During this period AF developed in 265 patients. The risk of developing AF was significantly greater in those individuals with the metabolic syndrome (hazard ratio 1.61, 95% CI 1.21-2.15), as well as in those with i ...
Catheter Ablation - STA HealthCare Communications
Catheter Ablation - STA HealthCare Communications

... patients in whom a rate control strategy is not an acceptable or is a poorly tolerated strategy and in whom antiarrhythmic agents have failed. Essentially, it should be considered an alternative to drug therapy. Success rates are highest for patients with normal or near normal hearts and these patie ...
When Diabetic Patients Need Compression Socks
When Diabetic Patients Need Compression Socks

... with more serious conditions – many of which can be associated with diabetes complications such as heart disease, venous insufficiency, and kidney disease. Certain diabetes medications can also cause edema. Did you know there is a difference between a diabetic sock and a diabetic compression sock? N ...
Left Ventricular Assist Devices
Left Ventricular Assist Devices

... common in patients with continuous flow LVADs. Patients who are unconscious do not necessarily need CPR. Cardiopulmonary resuscitation puts patients at risk for device dislodgment. 4. A 65 yo LVAD patient presents with upper GI bleeding. Why is bleeding common in LVAD patients? ...
The Right Ventricle: A Comprehensive Review From Anatomy
The Right Ventricle: A Comprehensive Review From Anatomy

... Whereas the LV is conical, the RV is more triangular and semilunar in form on vertical plans. The RV differs from the LV in that the former has strict trabeculae, a moderator band, and inter-valve fibrous tissues. Interestingly, the muscle mass of the RV is about one-sixth that of the LV. This could ...
Focused 2012 Update of the Canadian Cardiovascular Society Atrial
Focused 2012 Update of the Canadian Cardiovascular Society Atrial

... components (age 65-74, vascular disease, and female sex) contributed significantly to risk prediction in univariate analysis, but female sex did not make a significant contribution in a multivariate model. The value of assigning a point for female sex continues to be debated.11 The c-statistics were ...
Atrial Fibrillation - St. Joseph`s Healthcare Hamilton
Atrial Fibrillation - St. Joseph`s Healthcare Hamilton

... normal or sinus rhythm. This is a safe procedure carried out in hospital in a monitored setting with sedation. 3. Atrial fibrillation ablation ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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