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Percutaneous left ventricular assist devices in acute
Percutaneous left ventricular assist devices in acute

... These pumps are usually positioned across the aortic valve to provide active support by transvalvular LV assistance (Figure 3). In 1988, Wampler et al.27 were the first to describe an axial, catheter-mounted LVAD inserted by surgical arteriotomy via the femoral artery. The outer diameter was 21 Frenc ...
BME 311: BIOMEDICAL INSTRUMENTATION I Lecturer: Ali Işın
BME 311: BIOMEDICAL INSTRUMENTATION I Lecturer: Ali Işın

... BME 311 LECTURE NOTE 3 - ALİ IŞIN, 2014 ...
Original Contributions
Original Contributions

... evaluated in the psychologically stressed pig model and compared with Ringer's solution and D-propranolol (0.05 mg/kg). The ischemia of a maximum 15-minute left anterior descending coronary artery occlusion was used since we previously determined that pigs surviving 15 minutes usually do not fibrill ...
Pathophysiology of Congestive Heart Failure P A
Pathophysiology of Congestive Heart Failure P A

... of these two broad categories of heart failure have been the subject of numerous reports.2–5 Diastolic heart failure is largely a product of the aging population, occurring in patients with longstanding hypertension and left ventricular hypertrophy; however, it may also occur in patients with hypert ...
Thrombolysis in the Era of Intervention
Thrombolysis in the Era of Intervention

... gender, blood pressure, heart rate, prior MI and diabetes. The absolute mortality reduction was 30 per 1000 patients presenting within 0 - 6 hours and 20 per 1000 patients presenting between 7 and 12 hours. Beyond 12 hours, the benefit was uncertain. So, the earlier the treatment is administered, gr ...
Comments on the 2015 ESC Guidelines for the Management of
Comments on the 2015 ESC Guidelines for the Management of

... The writing has been simplified in this section and is more precise. The LVEF range of 30% to 40% and the differences between ischemic and nonischemic cardiomyopathy have been eliminated, and the same recommendations have been established for the 2 substrates (LVEF <35%). The new guidelines maintain ...
Heart Beats - Heart and Stroke Foundation of Manitoba
Heart Beats - Heart and Stroke Foundation of Manitoba

... Stroke Override, a challenge for corporate leaders is happening on June 19 in Brandon. For more information, call (204) 949.2000 or 1.888.473.4636. ...
One Pill Can Kill - Missouri Poison Center
One Pill Can Kill - Missouri Poison Center

... naloxone may help patients with respiratory depression, very high doses for prolonged periods may be needed, making supportive care the more appropriate choice for care. Calcium channel blockers (e.g., amlodipine, verapamil, diltiazem) can decrease cardiac inotropy and increase vasodilation. Hypergl ...
Atrial Natriuretic Peptide (1-28), rat (ANP 1-28)
Atrial Natriuretic Peptide (1-28), rat (ANP 1-28)

... in response to stress induced by increased afterload (eg. increased ventricular pressure from aortic stenosis) or injury (eg. myocardial infarction). ANP is secreted in response to: Atrial distention, stretching of the vessel walls Sympathetic stimulation of -adrenoceptors Raised sodium concentratio ...
Bextra
Bextra

... The evidence that led to this decision is compelling. The risks associated with a similar COX-2 inhibitor Vioxx are unequivocal. In fact in an elderly population at high risk for cardiovascular disease the estimated number needed to harm at high dose (50mg/d) Vioxx is 20. In other words for every 20 ...
Unstable angina: ST segment depression with positive
Unstable angina: ST segment depression with positive

... enzymatic criterion of infarction (twice the upper limit of normal creatine phosphokinase)were considered to have acute myocardial ischemia. The diagnosiscriteria for an evolving Q wave infarction was basedon the ECG appearance of new pathologic Q waves of 30 msec or longer appearing two or more con ...
Distribution Law and Dynamic Evolution of Zheng in TCM Jie Wang
Distribution Law and Dynamic Evolution of Zheng in TCM Jie Wang

... manifested as chest pain, but this sort of symptom could be categorized into several subtypes from the perspective of TCM. Specifically, stabbing chest pain is considered as Blood Stasis which is one type of Zhengs, while cold chest pain is identified as Yang Deficiency which is another type of Zhen ...
chronic cor pulmonale - Heart
chronic cor pulmonale - Heart

... hypertension, particularly in COPD patients. Similarly, the radiological signs of pulmonary hypertension (increased width of the right descending pulmonary artery) are poorly sensitive and the radiological appearance of a dilated right ventricle is a very late (and inconsistent) sign. The non-invasi ...
New Classification Of Haemodynamics Of Vasovagal Syncope
New Classification Of Haemodynamics Of Vasovagal Syncope

... swallowing) combined with negative above-mentioned investigations were included. Patients with associated carotid sinus hypersensitivity were also included. Carotid sinus hypersensitivity was defined as the reproduction of syncope in the presence of abnormal cardioinhibition (asystole >3 s), vasodep ...
The physiological role of endogenous endothelin in the
The physiological role of endogenous endothelin in the

... the beginning of the protocol and was not altered thereafter. Digital analysis was performed off-line with an edgedetection system (EasyVision, Philips) using a previously described and validated method (14,22,23). For each angiogram, diameter measurements were made (using geometric edge detection) ...
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...  Creatinine  Calcium  Urinalysis  Baseline thyroid studies (TSH) ...
Mortality and Predictors of Mortality in a Cohort of
Mortality and Predictors of Mortality in a Cohort of

... factors for many substances. © 2004 by the American Diabetes Association. ...
CSF Physiology and Cerebral Blood flow
CSF Physiology and Cerebral Blood flow

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Cyanotic CHD

... young child with CHF and  LE pulses Adult type presents with hypertension and difference in arm and leg pulses Rib notching - starts age 6-8 Often isolated Turner’s, NF, William’s, Sturge-Weber Primary repair Prostaglandin E to infants ...
Congenital heart disease is no longer a paediatric specialty
Congenital heart disease is no longer a paediatric specialty

... disease—congenital and acquired valve problems—adult cardiology has developed along a completely different direction over the decades. The main focus has changed to coronary artery disease, arrhythmias, and heart failure. The adult cardiologist has therefore become more and more unfamiliar with CHD. ...
Atrial Fibrillation - Annals of Internal Medicine
Atrial Fibrillation - Annals of Internal Medicine

... Should clinicians attempt rate control or rhythm control?  Traditionally clinicians preferred rhythm control to rate control  Recently high-quality clinical trials have found that rhythm control doesn’t improve mortality, stroke, hospitalization, or QOL compared with rate control  Rate control e ...
CORONARY CIRCULATION.
CORONARY CIRCULATION.

... 12.6 percent of deaths worldwide were from ischemic heart disease. Ischemic heart disease is the leading cause of death in developed countries, but third to AIDS and lower ...
3 stages
3 stages

... RHYTHM CONNECTIONS atrioventricular (nodal rhythm) occurs during the suppression of the sinoatrial node automaticity and retrograde propagation of the pulse of the atrioventricular connection. As a result of the ECG, there is recorded negative prong R. It precedes the complex QRS, appears simultaneo ...
ACLS Pharmacology Review
ACLS Pharmacology Review

... Dosing (How?) – Adjust to maintain activated partial thromboplastin time (aPTT) 1.5 to 2.0 times the control values for 48 hours or angiography – Target range for aPTT after first 24 hours is between 50 & 70 seconds (may vary with laboratory) – Check aPTT at 6, 12, 18, and 24 hours ...
3 stages
3 stages

... RHYTHM CONNECTIONS atrioventricular (nodal rhythm) occurs during the suppression of the sinoatrial node automaticity and retrograde propagation of the pulse of the atrioventricular connection. As a result of the ECG, there is recorded negative prong R. It precedes the complex QRS, appears simultaneo ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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