Cholecystokinin and GABA interaction in hippocampus in the
... 2.6. Statistical analysis All data were presented as mean±S.E.M. of %MPE related to ten animals in each group. One- or two-way ANOVA were used for analyzing data. Following a significant F-value, post-hoc Tukey’s test was performed to assess paired groups comparisons. P<0.05 was considered as statis ...
... 2.6. Statistical analysis All data were presented as mean±S.E.M. of %MPE related to ten animals in each group. One- or two-way ANOVA were used for analyzing data. Following a significant F-value, post-hoc Tukey’s test was performed to assess paired groups comparisons. P<0.05 was considered as statis ...
Charles University in Prague Faculty of Pharmacy in Hradec Králové
... As the theoretical background of this work, liposomes, its classification, materials used for preparing of liposomes, preparation techniques including dual asymmetric centrifugation, the principle of size exclusion chromatography and photon correlation spectroscopy, the drug triethylenetetramine and ...
... As the theoretical background of this work, liposomes, its classification, materials used for preparing of liposomes, preparation techniques including dual asymmetric centrifugation, the principle of size exclusion chromatography and photon correlation spectroscopy, the drug triethylenetetramine and ...
Clinical Pharmacology of Boceprevir (BOC): Metabolism
... BOC + RTV (100 mg QD) vs BOC ratio estimates (90% CI) AUC(T) 81% (73–91) Cmax 73% (57–93) Cmin 104% (62–175) ...
... BOC + RTV (100 mg QD) vs BOC ratio estimates (90% CI) AUC(T) 81% (73–91) Cmax 73% (57–93) Cmin 104% (62–175) ...
kopia+_Eli_PR5`2006.vp:CorelVentura 7.0
... ARE), piracetam (Nootropil, Chemical Industries Development; CID, Cairo, ARE), guanethidine, propranolol hydrochloride, yohimbine hydrochloride, naloxone hydrochloride (Sigma, St. Louis, USA), imipramine hydrochloride, bromocryptine (Novartis ...
... ARE), piracetam (Nootropil, Chemical Industries Development; CID, Cairo, ARE), guanethidine, propranolol hydrochloride, yohimbine hydrochloride, naloxone hydrochloride (Sigma, St. Louis, USA), imipramine hydrochloride, bromocryptine (Novartis ...
THE USE OF PURE AND IMPURE PLACEBO INTERVENTIONS IN
... Background: Placebos play an important role in clinical trials and several surveys have shown that they are also common in daily practice. Previous research focused primarily on the frequency of placebo use in outpatient care. Our aim was to explore physicians’ views on the use of placebos in daily ...
... Background: Placebos play an important role in clinical trials and several surveys have shown that they are also common in daily practice. Previous research focused primarily on the frequency of placebo use in outpatient care. Our aim was to explore physicians’ views on the use of placebos in daily ...
Effects of Different Doses of Simvastatin on Lead
... Department of Anatomy and Cell biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Neurogenic Inflammation Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. ...
... Department of Anatomy and Cell biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Neurogenic Inflammation Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. ...
anti-inflammatory, analgesic and antipyretic activities of the aqueous
... anti-inflammatory, analgesic and antipyretic activities in albino mice. Anti-inflammatory activity was evaluated by using carrageenan and albumin induced paw edema, while the analgesic effect was assessed by using formalin-induced paw licking and acetic acid induced abdominal writhing in mice. The b ...
... anti-inflammatory, analgesic and antipyretic activities in albino mice. Anti-inflammatory activity was evaluated by using carrageenan and albumin induced paw edema, while the analgesic effect was assessed by using formalin-induced paw licking and acetic acid induced abdominal writhing in mice. The b ...
The effect of topical benzamil and amiloride on nasal potential
... via a nasal spray whereas in HOFMANN et al. [18] the drugs were nebulized. It would seem likely that administration of a drug directly, via a nasal spray, would deliver a more concentrated dose to the nasal epithelium than delivery via a nebulizer. Similar to HOFMANN et al. [18], the current authors ...
... via a nasal spray whereas in HOFMANN et al. [18] the drugs were nebulized. It would seem likely that administration of a drug directly, via a nasal spray, would deliver a more concentrated dose to the nasal epithelium than delivery via a nebulizer. Similar to HOFMANN et al. [18], the current authors ...
Characterization of diffusion and duration of action of a
... distance ran, and total time ran. These data were recorded at daily intervals from the computers and logged for each cage, and the computers were reset. To condition animals prior to treatment, groups of eight animals were housed with free access to exercise wheels. At approximate threeday increment ...
... distance ran, and total time ran. These data were recorded at daily intervals from the computers and logged for each cage, and the computers were reset. To condition animals prior to treatment, groups of eight animals were housed with free access to exercise wheels. At approximate threeday increment ...
2 Long-acting agonists: a new perspective
... studies seems to be similar, whereas In isolated tissues there might be a difference In the binding characteristics to the ~ 2 -adrenoceptor. Longacting ~ 2 -agonlsts could have an inhibitory effect on Inflammatory events related to asthma, but the clinical relevance of these effects Is not clear at ...
... studies seems to be similar, whereas In isolated tissues there might be a difference In the binding characteristics to the ~ 2 -adrenoceptor. Longacting ~ 2 -agonlsts could have an inhibitory effect on Inflammatory events related to asthma, but the clinical relevance of these effects Is not clear at ...
Pharmaceutical Statistics Practical and Clinical Application
... This newest edition includes some significant additions. Most important is the inclusion of a coauthor, Charles (Chuck) Bon. Chuck has extensive practical experience as a chemist and statistician. His assistance in preparing the 4th edition adds some new dimensions, and new thoughts to the book. Ano ...
... This newest edition includes some significant additions. Most important is the inclusion of a coauthor, Charles (Chuck) Bon. Chuck has extensive practical experience as a chemist and statistician. His assistance in preparing the 4th edition adds some new dimensions, and new thoughts to the book. Ano ...
Journal of Forensic Toxicology and Pharmacology
... The antinociceptive activities of N. nubiae venom were evaluated using mice acetic acid-induced writhing test and rat tail immersion test. Acetic acid-induced writhing test Healthy male mice weighing (20-25 g) were used and withdrawn from food 2 hours before the start of experiment, and were divided ...
... The antinociceptive activities of N. nubiae venom were evaluated using mice acetic acid-induced writhing test and rat tail immersion test. Acetic acid-induced writhing test Healthy male mice weighing (20-25 g) were used and withdrawn from food 2 hours before the start of experiment, and were divided ...
the use of deuterium isotope effects to probe the active site
... The values of (kH/kD)obs found for cytochrome CYP2B1-catalyzed -hydroxylation of the dideuterated analog of n-octane, n-octane-1,82 H2, the heptadeuterated analog, n-octane-1,2,3-2H7, and the trideuterated analog, n-octane-1-2H3, of 16.11, 4.0, and 11.77, respectively, nicely illustrate the effects ...
... The values of (kH/kD)obs found for cytochrome CYP2B1-catalyzed -hydroxylation of the dideuterated analog of n-octane, n-octane-1,82 H2, the heptadeuterated analog, n-octane-1,2,3-2H7, and the trideuterated analog, n-octane-1-2H3, of 16.11, 4.0, and 11.77, respectively, nicely illustrate the effects ...
O A
... time (from initiation of first drug effect and passing of peak score and then achieving to normal state in animal). - Peak score for each dose: refer to the highest rate of CNS suppression in administrated dose. - Percentage of animal reached peak score: lost the reflexes (upon scores) for each dose ...
... time (from initiation of first drug effect and passing of peak score and then achieving to normal state in animal). - Peak score for each dose: refer to the highest rate of CNS suppression in administrated dose. - Percentage of animal reached peak score: lost the reflexes (upon scores) for each dose ...
EVALUATION OF THE ANTIINFLAMMATORY AND ANALGESIC EFFECTS OF PIROXICAM LOADED MICROEMULSION IN TOPICAL FORMULATIONS
... in microemulsion formulation incorporated in different pharmaceutical gel bases to the commercial product (Feldene Gel®). The anti‐inflammatory activity of the tested piroxicam formulations was evaluated using right hind paw oedema size of rats induced by carrageenan injection, while the analgesic ...
... in microemulsion formulation incorporated in different pharmaceutical gel bases to the commercial product (Feldene Gel®). The anti‐inflammatory activity of the tested piroxicam formulations was evaluated using right hind paw oedema size of rats induced by carrageenan injection, while the analgesic ...
T. Ishikawa, B. Mukai, S. Shiraishi, N. Utoguchi, M. Fujii, M
... showed that PH-M-06 was superior to PH-102 in terms of the feeling of roughness in the mouth. Consequently, it was found that particle size is an important factor for tablet preparation using microcrystalline cellulose. It is possible to prepare drugs such as acetaminophen and ascorbic acid (concent ...
... showed that PH-M-06 was superior to PH-102 in terms of the feeling of roughness in the mouth. Consequently, it was found that particle size is an important factor for tablet preparation using microcrystalline cellulose. It is possible to prepare drugs such as acetaminophen and ascorbic acid (concent ...
Suppression of laser-induced choroidal neovascularization
... and tranilast-treated groups. Electron microscopic evaluation revealed that new choroidal vessels were present within the lesions (graphic data not shown), but there was no apparent difference between the control and tranilast-treated groups. Body Weight Gain in Rats There was no significant differe ...
... and tranilast-treated groups. Electron microscopic evaluation revealed that new choroidal vessels were present within the lesions (graphic data not shown), but there was no apparent difference between the control and tranilast-treated groups. Body Weight Gain in Rats There was no significant differe ...
S3 File.
... studies reporting use of BoNT A therapy have studied ET patients [6,7,12], though a few studies have used IPD patients [13,14,15] Therefore, there is a deficit in understanding of the effects of BoNT A therapy for IPD tremor, and the complete lack of literature regarding BoNT A therapy efficacy for ...
... studies reporting use of BoNT A therapy have studied ET patients [6,7,12], though a few studies have used IPD patients [13,14,15] Therefore, there is a deficit in understanding of the effects of BoNT A therapy for IPD tremor, and the complete lack of literature regarding BoNT A therapy efficacy for ...
An extract of neem leaves reduces anxiety without causing motor
... suppression) to move. Therefore, in this study, we explored the use of neem leaves as a possible treatment for anxiety disorders using an established animal model of anxiety. Ethology is the study of animal behaviour with emphasis on the behavioural patterns that occur in natural environments. These ...
... suppression) to move. Therefore, in this study, we explored the use of neem leaves as a possible treatment for anxiety disorders using an established animal model of anxiety. Ethology is the study of animal behaviour with emphasis on the behavioural patterns that occur in natural environments. These ...
Retrospective Review of Trend in Modafinil Overexposures
... used by all US poison centers, the details of which are highlighted in Table 1 (18). Clinical manifestations of reported cases were not collected as the clinical effects of modafinil overdose have been previously described (2,3,12,13). Statistical analysis was performed using SPSS version 19 (IBM Co ...
... used by all US poison centers, the details of which are highlighted in Table 1 (18). Clinical manifestations of reported cases were not collected as the clinical effects of modafinil overdose have been previously described (2,3,12,13). Statistical analysis was performed using SPSS version 19 (IBM Co ...
Antihistamines in the treatment of asthma J . B
... There have been a number of trials performed in which no treatment for the nose or eyes was administered and, as a result, most of the placebotreated patients dropped out of the study (54-55]. Nasal and ocular symptoms should be treated during any asthma trial with drugs not affecting the interpreta ...
... There have been a number of trials performed in which no treatment for the nose or eyes was administered and, as a result, most of the placebotreated patients dropped out of the study (54-55]. Nasal and ocular symptoms should be treated during any asthma trial with drugs not affecting the interpreta ...
View Full Article in PDF - Knowledgebase publishers
... Noradrenalin and Euphorbia hirta Linn extract. Tracings were recorded using kymograph and its accessories. The procedure was repeated using the remaining 5 Rabbits. Statistical Analysis Results were expressed as Mean + Standard Error of Mean (SEM). Statistical analysis was performed by one-way analy ...
... Noradrenalin and Euphorbia hirta Linn extract. Tracings were recorded using kymograph and its accessories. The procedure was repeated using the remaining 5 Rabbits. Statistical Analysis Results were expressed as Mean + Standard Error of Mean (SEM). Statistical analysis was performed by one-way analy ...
PART II - Veterinary Medicines Directorate
... Adverse reactions (Frequency and Seriousness) Typical undesirable effects associated with NSAIDs, such as vomiting, soft faeces/diarrhea, faecal occult blood, loss of appetite and lethargy have been reported. These adverse reactions occur generally within the first treatment week and are in most cas ...
... Adverse reactions (Frequency and Seriousness) Typical undesirable effects associated with NSAIDs, such as vomiting, soft faeces/diarrhea, faecal occult blood, loss of appetite and lethargy have been reported. These adverse reactions occur generally within the first treatment week and are in most cas ...
Bioremoval of Antibiotics by Using Biodegradable Hydrogel Beads
... Elimination and proper disposal of pollutants of emerging concern are a major challenge in environmental remediation. On the other hand, biodegradable and naturally-occurring materials have been successfully used as adsorbents of inorganic and organic contaminants from solutions with very positive r ...
... Elimination and proper disposal of pollutants of emerging concern are a major challenge in environmental remediation. On the other hand, biodegradable and naturally-occurring materials have been successfully used as adsorbents of inorganic and organic contaminants from solutions with very positive r ...
... Very recently, CARLSEN et al. [30] evaluated the overnight protection against EIA afforded by 25 and 50 µg of dry powder salmeterol in children. No significant differences in pre- and postexercise lung function were found between the two doses 12 h after inhalation. Despite differences in times of a ...