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Lindsay Kinyon

... the octahedrally coordinated platinum family analogs, [Pt(N-N)3]4+ & [Pd(N-N)3]4+, most likely due to the difficulty of solvating the high charge density of the platinum (4+) & palladium (4+) ions. Early in the summer of 1996, Dr. Robert Granger developed a new, versatile scheme for the synthesis of ...
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DNA supercoil



DNA supercoiling refers to the over- or under-winding of a DNA strand, and is an expression of the strain on that strand. Supercoiling is important in a number of biological processes, such as compacting DNA. Additionally, certain enzymes such as topoisomerases are able to change DNA topology to facilitate functions such as DNA replication or transcription. Mathematical expressions are used to describe supercoiling by comparing different coiled states to relaxed B-form DNA.As a general rule, the DNA of most organisms is negatively supercoiled.
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