Autonomic regulation of islet hormone secretion
... consistent with equipotent insulinotropic effects of the two peptides [39]. Both VIP and PACAP stimulate insulin secretion in a glucose-dependent manner accompanied by increased action of adenylate cyclase with increased formation of cAMP [47, 48]. The latter also has other signalling actions in ins ...
... consistent with equipotent insulinotropic effects of the two peptides [39]. Both VIP and PACAP stimulate insulin secretion in a glucose-dependent manner accompanied by increased action of adenylate cyclase with increased formation of cAMP [47, 48]. The latter also has other signalling actions in ins ...
Highly specific radioimmunoassay for human insulin
... insulin. Indeed, immune exclusion of all insulin precursors by two MoAbs directed against the junction between A chain and C-peptide and the junction between B chain and C-peptide, respectively, leaves insulin as the sole reactant with the MoAb directed against the B chain. Effects of known amount o ...
... insulin. Indeed, immune exclusion of all insulin precursors by two MoAbs directed against the junction between A chain and C-peptide and the junction between B chain and C-peptide, respectively, leaves insulin as the sole reactant with the MoAb directed against the B chain. Effects of known amount o ...
recombiant drug
... the young medical student Paul Langerhans identified small areas of clear cells throughout the organ (islets of Langerhans). It was thought that they produced a secretion involved in digestion. Since then researchers have been trying to understand the role of these cells. In 1889, Oscar Minkowski an ...
... the young medical student Paul Langerhans identified small areas of clear cells throughout the organ (islets of Langerhans). It was thought that they produced a secretion involved in digestion. Since then researchers have been trying to understand the role of these cells. In 1889, Oscar Minkowski an ...
... Ghrelin has gained considerable attention over the last decade for its unique role in regulating mealtime hunger and lipid metabolism, as well as short- and long-term energy homeostasis (1). It is the only known circulating factor that promotes food intake and increases fat mass. Ghrelin is secreted ...
Insulin - Diabetes Care - American Diabetes Association
... The person administering insulin should inspect the bottle before each use for changes (i.e., clumping, frosting, precipitation, or change in clarity or color) that may signify a loss in potency. Visual examination should reveal rapid- and short-acting insulins as well as insulin glargine to be clea ...
... The person administering insulin should inspect the bottle before each use for changes (i.e., clumping, frosting, precipitation, or change in clarity or color) that may signify a loss in potency. Visual examination should reveal rapid- and short-acting insulins as well as insulin glargine to be clea ...
Elevated Hepatic Insulin Extraction in Essential Hypertension
... cholesterol levels did not differ between the two groups (Table 1). Hypertensive patients showed moderate microalbuminuria (98±8 mg/L in 24-hour sampled urine). The levels of uric acid were in the normal range in hypertensive patients (Table 1) but were significantly elevated compared with control s ...
... cholesterol levels did not differ between the two groups (Table 1). Hypertensive patients showed moderate microalbuminuria (98±8 mg/L in 24-hour sampled urine). The levels of uric acid were in the normal range in hypertensive patients (Table 1) but were significantly elevated compared with control s ...
The Catabolic Action of Insulin in the Brain Is Mediated
... Body weight is regulated by a complex interaction of peripheral signals with central pathways that influence food intake and energy expenditure. Understanding the high degree of accuracy displayed by most mammals to maintain energy balance is fundamental to our knowledge of how homeostatic systems f ...
... Body weight is regulated by a complex interaction of peripheral signals with central pathways that influence food intake and energy expenditure. Understanding the high degree of accuracy displayed by most mammals to maintain energy balance is fundamental to our knowledge of how homeostatic systems f ...
Upregulated insulin secretion in insulin-resistant
... augmented meal-induced GLP-1 and insulin responses to GPR119 activation with an increased glucose elimination. However, the concurrent increase in glucagon may decrease the antihyperglycemic response by the insulinotropic effects of GLP-1 and GPR119 agonism, resulting in only marginally improved glu ...
... augmented meal-induced GLP-1 and insulin responses to GPR119 activation with an increased glucose elimination. However, the concurrent increase in glucagon may decrease the antihyperglycemic response by the insulinotropic effects of GLP-1 and GPR119 agonism, resulting in only marginally improved glu ...
insulin and glucagon responses in the hibernating black bear
... mechanism(s) as yet unknown. One possible explanation is that the decrease in the glomerular filtration rate during hibernation (Brown et al. 1971) results in a decrease in insulin clearanceby the kidney. It would be interesting to speculate that the delay in insulin disappearancemay help ...
... mechanism(s) as yet unknown. One possible explanation is that the decrease in the glomerular filtration rate during hibernation (Brown et al. 1971) results in a decrease in insulin clearanceby the kidney. It would be interesting to speculate that the delay in insulin disappearancemay help ...
Evaluation of Growth Differentiation Factor-15 in Non
... differentiation factor-15 in non-diabetic hypothyroid patients with normal insulin sensitivity. Subjects and Methods: The case-control study comprised of 85 subjects as a total, among them 33 hypothyroid patients aging between 40 to 60 years and 52 apparently healthy subjects of comparable age, weig ...
... differentiation factor-15 in non-diabetic hypothyroid patients with normal insulin sensitivity. Subjects and Methods: The case-control study comprised of 85 subjects as a total, among them 33 hypothyroid patients aging between 40 to 60 years and 52 apparently healthy subjects of comparable age, weig ...
Inpatient Blood Glucose Control Facts and Guidelines (For all
... Use the hospital’s Precision meter to check the FSBGs; if patient has brought in their own meter, explain we have to use our hospital meter since it documents the results. • Nutrition Goal = to achieve / maintain ideal body weight; FSBGs <180, and optimal blood lipid levels. Patient should be ...
... Use the hospital’s Precision meter to check the FSBGs; if patient has brought in their own meter, explain we have to use our hospital meter since it documents the results. • Nutrition Goal = to achieve / maintain ideal body weight; FSBGs <180, and optimal blood lipid levels. Patient should be ...
Neural control of the endocrine pancreas
... Anatomical studies indicate abundant evidence for the multiple innervation of pancreatic islets (Fig. 4). Physiological studies show that many of the secretory phenomena of the pancreas are directly under neuronal influence, especially via the vagus, splanchnic, and VIP-containing nerves. There is n ...
... Anatomical studies indicate abundant evidence for the multiple innervation of pancreatic islets (Fig. 4). Physiological studies show that many of the secretory phenomena of the pancreas are directly under neuronal influence, especially via the vagus, splanchnic, and VIP-containing nerves. There is n ...
The Endocrine Pancreas
... Insulin is secreted in primarily in response to elevated blood concentrations of glucose. Some neural stimuli (e.g. site and taste of food) and increased blood concentrations of other fuel molecules, including amino acids and fatty acids, also promote insulin secretion. Glucose is transported into t ...
... Insulin is secreted in primarily in response to elevated blood concentrations of glucose. Some neural stimuli (e.g. site and taste of food) and increased blood concentrations of other fuel molecules, including amino acids and fatty acids, also promote insulin secretion. Glucose is transported into t ...
Adipose Tissue and Insulin Resistance
... are the main source of TNF-F in adipose tissue (14). TNF-F expression is higher in visceral fat (VF) of rodents than in subcutaneous (sc) fat (25). In addition, TNF-F has been shown to impair insulin signaling in cultured cells by three separate molecular mechanisms. TNF-F activates serine/threonine ...
... are the main source of TNF-F in adipose tissue (14). TNF-F expression is higher in visceral fat (VF) of rodents than in subcutaneous (sc) fat (25). In addition, TNF-F has been shown to impair insulin signaling in cultured cells by three separate molecular mechanisms. TNF-F activates serine/threonine ...
Endocrine Functions of Pancreas O B J E C T I V E S After reading
... Insulin Deficiency Causes Lipolysis of Storage Fat and Releaseof Free Fatty Acids. In the absence of insulin, all the effects of insulin noted earlier that cause storage of fat are reversed. The most important effect is that the enzyme hormone-sensitive lipase in the fat cells becomes strongly activ ...
... Insulin Deficiency Causes Lipolysis of Storage Fat and Releaseof Free Fatty Acids. In the absence of insulin, all the effects of insulin noted earlier that cause storage of fat are reversed. The most important effect is that the enzyme hormone-sensitive lipase in the fat cells becomes strongly activ ...
Dear Notetaker:
... o Glucagon will convert the amino acids into glucose o Will have necessary glucose for metabolism o Glucagon also stimulates fatty acid break down fat loss - Amino acids potentiates effects of glucose on insulin secretion o High amounts of amino acid does not directly cause insulin secretion - Glu ...
... o Glucagon will convert the amino acids into glucose o Will have necessary glucose for metabolism o Glucagon also stimulates fatty acid break down fat loss - Amino acids potentiates effects of glucose on insulin secretion o High amounts of amino acid does not directly cause insulin secretion - Glu ...
diabetes in cats
... Australian cats [Lederer 2009]), with British and Australian Burmese being significantly over-‐represented at 3.7 and 3 fold, respectively. Fasting glucose concentrations are higher and glucose tolerance is lower ...
... Australian cats [Lederer 2009]), with British and Australian Burmese being significantly over-‐represented at 3.7 and 3 fold, respectively. Fasting glucose concentrations are higher and glucose tolerance is lower ...
Chapter 37 - BristolPlymouth21stCenturyHealth
... amounts but insulin receptors in target cells insensitive or resistant to insulin Common in overweight clients and those having low HDL-cholesterol and high triglyceride levels ...
... amounts but insulin receptors in target cells insensitive or resistant to insulin Common in overweight clients and those having low HDL-cholesterol and high triglyceride levels ...
Insulin resistance index versus glycerol and free
... could be only speculated. However, the contribution of female sex hormones in the regulation of insulin sensitivity has to be taken into consideration. It is well documented that disturbed ovarian hormone secretion and subsequent hyperandrogenism brings about insulin resistance [10,42]. Moreover, in ...
... could be only speculated. However, the contribution of female sex hormones in the regulation of insulin sensitivity has to be taken into consideration. It is well documented that disturbed ovarian hormone secretion and subsequent hyperandrogenism brings about insulin resistance [10,42]. Moreover, in ...
corticosteroids - LaGuardia ePortfolio
... healthy also prevent lipodystrophy (a medical condition characterized by abnormal or degenerative conditions of the body's adipose tissue). ...
... healthy also prevent lipodystrophy (a medical condition characterized by abnormal or degenerative conditions of the body's adipose tissue). ...
Determination of Insulin Levels in Human Serum
... Insulin is a polypeptide hormone with a molecular weight of approximately 5800 that plays a critical role the regulation of blood glucose levels. Its production and secretion by beta cells in the islets of Langerhans is tightly regulated under normal conditions. Type I diabetes is caused by the dest ...
... Insulin is a polypeptide hormone with a molecular weight of approximately 5800 that plays a critical role the regulation of blood glucose levels. Its production and secretion by beta cells in the islets of Langerhans is tightly regulated under normal conditions. Type I diabetes is caused by the dest ...
Daruka K. M 1 - journal of evidence based medicine and healthcare
... INTRODUCTION: Thyroid disease is widespread in women than men and women are five to eight times more likely to develop hypothyroidism. Thyroid illness can increase the risk of cardiovascular disease, infertility, and osteoporosis.(1) The association between thyroid function and body weight in euthyr ...
... INTRODUCTION: Thyroid disease is widespread in women than men and women are five to eight times more likely to develop hypothyroidism. Thyroid illness can increase the risk of cardiovascular disease, infertility, and osteoporosis.(1) The association between thyroid function and body weight in euthyr ...