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File - MRS. WILSON Science
File - MRS. WILSON Science

... information flows in one direction, from DNA to RNA to proteins. Like DNA, RNA is a nucleic acid. It is made of nucleotides that consist of a phosphate group, a sugar, and a nitrogen-containing base. However, RNA differs in important ways from DNA: (1) RNA contains the sugar ribose, not deoxyribose; ...
Modeling Genetic Engineering Lab
Modeling Genetic Engineering Lab

... An understanding of the basis of inheritance has led to a new form of applied genetics called genetic engineering. Genetic engineering is the use of genetics for practical purposes. For example, it can be used to identify genes for specific traits or transfer genes for a specific trait from one orga ...
basic genetics for the clinical neurologist
basic genetics for the clinical neurologist

... The process of converting the genetic information in the DNA sequence into a protein product is schematically represented in fig 1. Synthesis of a protein begins with an appropriate signalling molecule binding to the promoter of the gene. This initiates a process called transcription. Transcription ...
3-24-16 Genetics and Heredity 12.3
3-24-16 Genetics and Heredity 12.3

... • DNA is bundled together as chromosomes • Different parts of a chromosome make up genes Gene: the factors that control a trait. The sequence of DNA that determines a trait and is passed from parent to offspring. • You can have different forms of a gene that does the same thing. This is called an al ...
Evolution of genomes
Evolution of genomes

... the existence of highly repetitive non-coding DNA produced by transposable elements. ...
Chapter 21
Chapter 21

... (previously called “junk DNA” plays important roles in the cell • For example, genomes of humans, rats, and mice show high sequence conservation for about 500 noncoding regions ...
CSCE590/822 Data Mining Principles and Applications
CSCE590/822 Data Mining Principles and Applications

... ◦ Obtain random sequence reads from a genome ◦ Assemble them into contigs on the basis of sequence overlaps  Straightforward for simple genomes (with no or few repeat sequences)  Merge reads containing overlapping sequence ...
Definition of a Gene - Kaikoura High School
Definition of a Gene - Kaikoura High School

... • The power source is turned on and the gel is run. The time of the run depends upon the amount of current and % gel, and requires experimentation • At the end of the run the gel is removed (it is actually quite stiff) • The gel is then visualized - UV light causes the bands of DNA to fluoresce ...
2. recombinant gene
2. recombinant gene

... Foreign gene – stable gene expression ...
1. dia
1. dia

... Foreign gene – stable gene expression ...
Chemical Structure of Deoxyribonucleic Acid. Evidences, DNA is
Chemical Structure of Deoxyribonucleic Acid. Evidences, DNA is

... Although the name nucleic acid suggests their location in the nuclei of cells, yet some of them are, however, also present in the cytoplasm. The nucleic acids are the hereditary determinants of living organisms. They are the macromolecules present in most living cells either in the free state or bou ...
polymorphism
polymorphism

... 8. Add 500 l of Qiagen buffer AW2 without wetting the spin column rim. Centrifuge at 14,000 for 3 minutes. Complete removal of the AW2 buffer is necessary as its presence would prevent subsequent resolubilization of the DNA trapped in the spin column. Therefore, carefully remove the 2 ml microfuge ...
Biology (CP) Final Exam Study Guide 3
Biology (CP) Final Exam Study Guide 3

... c. The number of replication forks on a strand of DNA. d. The total amount of DNA in a cell. ____ 51. In both prokaryotes and eukaryotes, how many copies of the chromosome are left after replication? a. 1 b. 2 c. 3 d. 4 ____ 52. Eukaryotic cells can have up to how many times more DNA than prokaryoti ...
Human Gene Editing
Human Gene Editing

... to a sequence that matches the CRISPR, said John Reidhaar-Olson, a biochemist at Albert Einstein College of Medicine in New York, who was not involved in the study. Then, the Cas9 cuts the DNA. Lastly, the cell repairs the cut, in this case by inserting a piece of DNA supplied by the experimenter, R ...
Meiosis to Mendel
Meiosis to Mendel

... sexually has two copies of each chromosome, and therefore has two copies of every gene – one on each member of each pair of chromosomes (exception is the Y chromosome, which is smaller than the X).  The two versions of each gene are called alleles. Alleles may be the same or different, depending on ...
Human Genetics
Human Genetics

... Polyploidy is common in the plant kingdom, spontaneous origin of polyploid individuals plays important role in evolution of plants. In the animal kingdom, natural occurrence of polyploids is extremely rare. In general, polyploids are more nearly normal in appearance than having monosomy or trisomy, ...
Genes
Genes

... Only a fraction of eukaryotic DNA codes for proteins or RNA molecules: 1.1% of human genome represents protein-coding genes Coding regions are not continuous ( Split genes), contains exons and introns. Introns often account for most of the gene size.: BRCA-1 (Chr 17) 100,000 bp. Codes for a protein ...
Review Materials for Chapter 14-16
Review Materials for Chapter 14-16

... marries a color-blind woman of normal height. The man's father was six feet tall, and both the woman's parents were of average height. Achondroplastic dwarfism is autosomal dominant, and red-green color blindness is X-linked recessive. How many of their female children might be expected to be color- ...
ENGLISH FOR MAJOR
ENGLISH FOR MAJOR

... • These terms hadn’t yet been defined. ...
SK_DifficultProblems.
SK_DifficultProblems.

... e.g. Purine and Pyrimidine transitions ...
Introduction to Genetics
Introduction to Genetics

... No one really knows what determines the number of chromosomes in an organism, though related species tend to have similar chromosome numbers. This is because chromosomes may split or combine during evolution and speciation. While humans have 46, other great apes have 48. It is important to remember ...
First week lectures
First week lectures

... From storage to machines ...
File
File

... 1. lactose binds to the repressor protein 2. It changes the shape (structure) of the repressor protein 3. This change stops the repressor protein binding to the operator 4. So RNA polymerase is able to bind to promoter 5. Z and Y are transcribed and the mRNA is made 6. As a result, the bacteria can ...
Unit 11.1 Gene Transfer
Unit 11.1 Gene Transfer

... What are the basic functions of DNA and RNA? A. DNA - deoxyribonucleic acid is a very complex substance composed of large molecules that are capable of being put together in an almost unlimited number of ways. B. DNA - make up chromosomes. Chromosomes are contributed by each parent and determine how ...
Sex-linked, Mitochondrial Inheritance (Learning Objectives
Sex-linked, Mitochondrial Inheritance (Learning Objectives

... • Imprint is erased in germline cells and reestablished. – In testes, parental imprint is reset – In ovaries, maternal imprint is reset ...
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Extrachromosomal DNA



Extrachromosomal DNA is any DNA that is found outside of the nucleus of a cell. It is also referred to as extranuclear DNA or cytoplasmic DNA. Most DNA in an individual genome is found in chromosomes but DNA found outside of the nucleus also serves important biological functions.In prokaryotes, nonviral extrachromosomal DNA is primarily found in plasmids whereas in eukaryotes extrachromosomal DNA is primarily found in organelles. Mitochondrial DNA is a main source of this extrachromosomal DNA in eukaryotes. Extrachromosomal DNA is often used in research of replication because it is easy to identify and isolate.Extrachromosomal DNA was found to be structurally different from nuclear DNA. Cytoplasmic DNA is less methylated than DNA found within the nucleus. It was also confirmed that the sequences of cytoplasmic DNA was different from nuclear DNA in the same organism, showing that cytoplasmic DNAs are not simply fragments of nuclear DNA.In addition to DNA found outside of the nucleus in cells, infection of viral genomes also provides an example of extrachromosomal DNA.
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