during the Somatic Hypermutation Process Trends in Antibody
... The L and H chain matching is handled using a similar exhaustive procedure. In each case the V genes are matched first near the N terminus of the sequence, and the best match is retained. The unmatched portion of the sequence is then extracted, and the best J gene match is found using a similar proc ...
... The L and H chain matching is handled using a similar exhaustive procedure. In each case the V genes are matched first near the N terminus of the sequence, and the best match is retained. The unmatched portion of the sequence is then extracted, and the best J gene match is found using a similar proc ...
A Mechanistic Beta-Binomial Probability Model for mRNA
... two (or more) conditions. By analyzing the genes which show up on such lists, one can identify larger functional units such as biological processes, pathways, networks, and organelles that are involved in the response, giving clear hypotheses for further targeted experiments [9–13]. The centralized ...
... two (or more) conditions. By analyzing the genes which show up on such lists, one can identify larger functional units such as biological processes, pathways, networks, and organelles that are involved in the response, giving clear hypotheses for further targeted experiments [9–13]. The centralized ...
fig. 1 - Utrecht University Repository
... inspired by recent findings on antagonistic interactions in Vibrionaceae populations. We find toxin genes evolve to be highly mobile, whereas resistance genes minimize mobility. This differential gene mobility is a requirement to maintain a diverse and dynamic ecosystem. The resistance gene repertoi ...
... inspired by recent findings on antagonistic interactions in Vibrionaceae populations. We find toxin genes evolve to be highly mobile, whereas resistance genes minimize mobility. This differential gene mobility is a requirement to maintain a diverse and dynamic ecosystem. The resistance gene repertoi ...
Operophtera brumata with pheromone-baited traps, December 2005
... hybridization of swallowtail butterflies. The occurrence of hybrids has important implications for the success of the biological control effort versus winter moths. We have also begun work on an identification system based on restriction enzymes that we hope will provide a reliable and inexpensive w ...
... hybridization of swallowtail butterflies. The occurrence of hybrids has important implications for the success of the biological control effort versus winter moths. We have also begun work on an identification system based on restriction enzymes that we hope will provide a reliable and inexpensive w ...
The Plastidic Phosphoglucomutase from
... (Casey et al., 1998). These studies indicated that plastidic PGM not only plays an essential role in starch synthesis, but also has a significant impact on the deposition of other storage products in seeds. The synthesis of a number of commercially important products in seeds, including starch and f ...
... (Casey et al., 1998). These studies indicated that plastidic PGM not only plays an essential role in starch synthesis, but also has a significant impact on the deposition of other storage products in seeds. The synthesis of a number of commercially important products in seeds, including starch and f ...
Clinical Laboratory Reports in Molecular Pathology
... stated. This is expressed as a normal range for a quantitative test, along with the units of measurement. Interassay reproducibility is an important parameter that allows a clinician to determine whether 2 sequential test results are significantly different from each other, and information about ass ...
... stated. This is expressed as a normal range for a quantitative test, along with the units of measurement. Interassay reproducibility is an important parameter that allows a clinician to determine whether 2 sequential test results are significantly different from each other, and information about ass ...
FREE Sample Here - Test bank Store
... Answer: To be a good genetic model, an organism has to have a well-known genetic history, a short life cycle, produce many offspring, be easy to handle, and have genetic variability among the individuals in a population. Skill: Factual recall 47) Why are genetic databases so important to the study o ...
... Answer: To be a good genetic model, an organism has to have a well-known genetic history, a short life cycle, produce many offspring, be easy to handle, and have genetic variability among the individuals in a population. Skill: Factual recall 47) Why are genetic databases so important to the study o ...
The dual nature of homologous recombination in plants
... ability to produce targeted changes in plant genes would have a tremendous impact on fundamental research and on molecular breeding. However, the frequency of one targeted event per 104–106 transformants is too low to be routinely used [62,63] (discussed in Refs [6,7,64]). Stimulation of HR in the c ...
... ability to produce targeted changes in plant genes would have a tremendous impact on fundamental research and on molecular breeding. However, the frequency of one targeted event per 104–106 transformants is too low to be routinely used [62,63] (discussed in Refs [6,7,64]). Stimulation of HR in the c ...
An Experimental Program for Introducing First
... The field of Cell Biology encompasses a vast array of subjects. Although it is important for instructors to cover a broad range of topics, it is also important to allow students to delve into specific subjects using discovery based learning (Wilke et al, 2001). A group of students were introduced to ...
... The field of Cell Biology encompasses a vast array of subjects. Although it is important for instructors to cover a broad range of topics, it is also important to allow students to delve into specific subjects using discovery based learning (Wilke et al, 2001). A group of students were introduced to ...
The Nucleotide Sequence Determination of Catalases of Three
... tropicalis clinical strain NUM 507616） and determined the whole nucleotide sequence（GenBank/ EMBL/DDBJ accession no.: AB181391）. Homology between the ORF regions of the two catalases was 84.5% in nucleotides and 94.6% in amino acids. These are low scores as compared with the value between catalase s ...
... tropicalis clinical strain NUM 507616） and determined the whole nucleotide sequence（GenBank/ EMBL/DDBJ accession no.: AB181391）. Homology between the ORF regions of the two catalases was 84.5% in nucleotides and 94.6% in amino acids. These are low scores as compared with the value between catalase s ...
Microbial Gene Transfer: An Ecological
... recent evidence from natural populations as well as genome research has indicated that this process may be a major driving force in microbial evolution. Studies with natural populations have taken two approacheseither adding a defined donor with a traceable gene to an indigenous community, and detec ...
... recent evidence from natural populations as well as genome research has indicated that this process may be a major driving force in microbial evolution. Studies with natural populations have taken two approacheseither adding a defined donor with a traceable gene to an indigenous community, and detec ...
Flexible expressed region analysis for RNA
... base-resolution analysis, which performs coverage calculation, preprocessing, statistical modeling, region annotation and data visualization. This software permits differential expression analysis at both the single base level, resulting in direct calculation of DERs (20), and a feature summarizatio ...
... base-resolution analysis, which performs coverage calculation, preprocessing, statistical modeling, region annotation and data visualization. This software permits differential expression analysis at both the single base level, resulting in direct calculation of DERs (20), and a feature summarizatio ...
RecA maintains the integrity of chloroplast DNA molecules in
... nuclear genomes of many organisms, including plants (Lin et al., 2006). Repair and recombination of chloroplast DNA (cpDNA) in Chlamydomonas reinhardtii is suppressed when a dominant-negative version of E. coli RecA is targeted to chloroplasts (Cerutti et al., 1995). The prevalence of chloroplast-ta ...
... nuclear genomes of many organisms, including plants (Lin et al., 2006). Repair and recombination of chloroplast DNA (cpDNA) in Chlamydomonas reinhardtii is suppressed when a dominant-negative version of E. coli RecA is targeted to chloroplasts (Cerutti et al., 1995). The prevalence of chloroplast-ta ...
Gene Section FANCF (Fanconi anemia, complementation group F)
... would induce its translocation into the nucleus.This FA complex translocates into the nucleus, where FANCE and FANCF are present; FANCE and FANCF join the complex. The FA complex subsequently interacts with FANCD2 by monoubiquitination of FANCD2 during S phase or following DNA damage. Activated (ubi ...
... would induce its translocation into the nucleus.This FA complex translocates into the nucleus, where FANCE and FANCF are present; FANCE and FANCF join the complex. The FA complex subsequently interacts with FANCD2 by monoubiquitination of FANCD2 during S phase or following DNA damage. Activated (ubi ...
Nucleotide Polymorphisms in the 2 Gene Define
... different levels of a2b1 revealed two linked nucleotide polymorphisms, separated by almost seventy nucleotides, at bp 807 and 873 in the a2 coding region. These were the only two nucleotide polymorphisms identified within the ,3.5-kb a2 coding region that consistently varied among the samples studie ...
... different levels of a2b1 revealed two linked nucleotide polymorphisms, separated by almost seventy nucleotides, at bp 807 and 873 in the a2 coding region. These were the only two nucleotide polymorphisms identified within the ,3.5-kb a2 coding region that consistently varied among the samples studie ...
HMG 9_9.book(ddd146.fm)
... In order to evaluate the prevalence of RTT related to MECP2 mutations, we have carried out a systematic analysis of the MECP2 gene in 46 typical RTT patients and screened by DGGE (n = 38) and by direct sequencing (n = 8) the whole coding sequence of this gene. Upon analysis by DGGE of exon 1 to exon ...
... In order to evaluate the prevalence of RTT related to MECP2 mutations, we have carried out a systematic analysis of the MECP2 gene in 46 typical RTT patients and screened by DGGE (n = 38) and by direct sequencing (n = 8) the whole coding sequence of this gene. Upon analysis by DGGE of exon 1 to exon ...
Chapter 27 Phage Strategies
... host RNA polymerase following infection include, or comprise, regulators required for expression of the middle (or delayed early) set of phage genes. • The middle group of genes includes regulators to transcribe the late genes. • This results in the ordered expression of groups of genes during phage ...
... host RNA polymerase following infection include, or comprise, regulators required for expression of the middle (or delayed early) set of phage genes. • The middle group of genes includes regulators to transcribe the late genes. • This results in the ordered expression of groups of genes during phage ...
Functional and ecological impacts of horizontal gene transfer in
... environments is well known. This is exemplified by the high level of HGT observed in the genome of the thermoacidophile Thermotoga, which has acquired genes relating to its environment and metabolism from archaebacteria inhabiting similar environments [30,31]. The possible role of HGT in adapting to ...
... environments is well known. This is exemplified by the high level of HGT observed in the genome of the thermoacidophile Thermotoga, which has acquired genes relating to its environment and metabolism from archaebacteria inhabiting similar environments [30,31]. The possible role of HGT in adapting to ...
2. Primer Design
... well. If the template is genomic DNA, try a 250 ng/microliter solution of DNA. PCR can be finicky, and you may have to play with these amounts depending on the situation. ...
... well. If the template is genomic DNA, try a 250 ng/microliter solution of DNA. PCR can be finicky, and you may have to play with these amounts depending on the situation. ...
A recurrent deletion syndrome at chromosome bands 2p11
... speech delay, delayed motor development and minor facial anomalies such as high forehead, broad nasal bridge and large low set ears (Table 1). Despite the very large size of the del(2)(p11.2p12), the clinical phenotype is relatively mild when compared generally with similar-sized deletions reported ...
... speech delay, delayed motor development and minor facial anomalies such as high forehead, broad nasal bridge and large low set ears (Table 1). Despite the very large size of the del(2)(p11.2p12), the clinical phenotype is relatively mild when compared generally with similar-sized deletions reported ...
Optimization of the RT-PCR Method Using the TitanTM One Tube
... one after the other, but without any more addition of reagents. A distinction is made between two approaches: a. The use of T. thermophilus-(Tth-)DNA polymerase which, like reverse transcriptase, is active in the presence of manganese and, moreover, accepts both RNA and DNA as matrix, enables the wh ...
... one after the other, but without any more addition of reagents. A distinction is made between two approaches: a. The use of T. thermophilus-(Tth-)DNA polymerase which, like reverse transcriptase, is active in the presence of manganese and, moreover, accepts both RNA and DNA as matrix, enables the wh ...
A set reduction and pattern matching problem motivated by Allele
... box) allowing extension of the primers by DNA polymerase. 1) After one iteration the process has created two copies of the original sequence (navy boxes). One copy begins with the left primer, and the other begins with the right primer. 2) A second iteration doubles the number of sequences by duplic ...
... box) allowing extension of the primers by DNA polymerase. 1) After one iteration the process has created two copies of the original sequence (navy boxes). One copy begins with the left primer, and the other begins with the right primer. 2) A second iteration doubles the number of sequences by duplic ...
Nucleotide sequence and genome organization of foot-and
... These difficulties seem to be related to the internal poly(C) tract, which, although readily copied into cDNA (7), is probably highly unstable in E. coli, as shown for other (GtC)-homopolymers longer than 30 basepairs (19). In accordance with this notion we have only been able to clone 11 C residues ...
... These difficulties seem to be related to the internal poly(C) tract, which, although readily copied into cDNA (7), is probably highly unstable in E. coli, as shown for other (GtC)-homopolymers longer than 30 basepairs (19). In accordance with this notion we have only been able to clone 11 C residues ...
Genetic Control of Meat Quality Traits
... These are major welfare problems as well as threatening productivity. In addition, the inadvertent selection for genetic defects linked to desirable production characteristics is a potential risk, especially when selection programes focus on a limited number of breeding individuals. The traits that ...
... These are major welfare problems as well as threatening productivity. In addition, the inadvertent selection for genetic defects linked to desirable production characteristics is a potential risk, especially when selection programes focus on a limited number of breeding individuals. The traits that ...
A Large Pseudoautosomal Region on the Sex Chromosomes of the
... sex chromosome divergence resulting from suppressed recombination and involves the loss of coding regions, the accumulation of repetitive regions, and structural changes such as insertions, deletions, and inversions on the sex-specific chromosome (the Y or W). Thus, degenerate sex chromosomes have d ...
... sex chromosome divergence resulting from suppressed recombination and involves the loss of coding regions, the accumulation of repetitive regions, and structural changes such as insertions, deletions, and inversions on the sex-specific chromosome (the Y or W). Thus, degenerate sex chromosomes have d ...