Genetic Causes of Phenotypic Adaptation to the Second
... The values of each parameter for the diploid and haploid parental strains are shown in Table 2. The kinetic parameters between haploid and diploid forms did not show significant differences, except for the rate. Haploids exhibited a significantly higher fermentation rate, certainly due to the ploidy ...
... The values of each parameter for the diploid and haploid parental strains are shown in Table 2. The kinetic parameters between haploid and diploid forms did not show significant differences, except for the rate. Haploids exhibited a significantly higher fermentation rate, certainly due to the ploidy ...
Identification of a cystic fibrosis mutation W19X in Tunisia
... transmembrane conductance regulator gene (CFTR). The frequencies of mutations vary according to the ethnic origin of populations. We describe in this study a patient with cystic fibrosis. She was homozygous for a new nonsense mutation identified for the first time in Tunisia: W19X, which expected to ...
... transmembrane conductance regulator gene (CFTR). The frequencies of mutations vary according to the ethnic origin of populations. We describe in this study a patient with cystic fibrosis. She was homozygous for a new nonsense mutation identified for the first time in Tunisia: W19X, which expected to ...
M.Sc., Biotechnology - Alagappa University
... technology that helps to understand the cellular and molecular processes of biological system. Though many definitions exist for the term biotechnology, the most accepted definition proposed for biotechnology by The American Chemical Society is “The application of biological organisms, systems, or p ...
... technology that helps to understand the cellular and molecular processes of biological system. Though many definitions exist for the term biotechnology, the most accepted definition proposed for biotechnology by The American Chemical Society is “The application of biological organisms, systems, or p ...
Ascorbate peroxidaserelated (APxR) is a new
... plants, which contain only APx, chloroplastic organisms contain both APx and CcP sequences. Purification of chloroplastic APx from tea (Camellia sinensis) leaves has indicated that the enzyme is a 34-kDa monomer that is labile in the absence of ascorbate (Chen & Asada, 1989). However, purification o ...
... plants, which contain only APx, chloroplastic organisms contain both APx and CcP sequences. Purification of chloroplastic APx from tea (Camellia sinensis) leaves has indicated that the enzyme is a 34-kDa monomer that is labile in the absence of ascorbate (Chen & Asada, 1989). However, purification o ...
Standard Genetic Nomenclature - Iowa State University Digital
... the GO Consortium was formed to standardize functional annotation in the form of gene ontologies that can be used across all eukaryotes (Gene Ontology Consortium, 2000). This effort not only provided a standard method for functional annotation but also promoted data sharing and enabled modelling of ...
... the GO Consortium was formed to standardize functional annotation in the form of gene ontologies that can be used across all eukaryotes (Gene Ontology Consortium, 2000). This effort not only provided a standard method for functional annotation but also promoted data sharing and enabled modelling of ...
Standard Genetic Nomenclature - Iowa State University Digital
... the GO Consortium was formed to standardize functional annotation in the form of gene ontologies that can be used across all eukaryotes (Gene Ontology Consortium, 2000). This effort not only provided a standard method for functional annotation but also promoted data sharing and enabled modelling of ...
... the GO Consortium was formed to standardize functional annotation in the form of gene ontologies that can be used across all eukaryotes (Gene Ontology Consortium, 2000). This effort not only provided a standard method for functional annotation but also promoted data sharing and enabled modelling of ...
Solid Tumour Section Mesothelioma: t(14;22)(q32;q12) in mesothelioma Atlas of Genetics and Cytogenetics
... number NM_013986 version 3; former exon 7 in sequence with accession number X66899) is fused to exon 2 of YY1 (nucleotide 1160 accession number NM_003403 version 3). The putative EWSR1-YY1 protein would contain the transactivation domain of EWSR1 and the DNA binding domain of YY1 and thus may act as ...
... number NM_013986 version 3; former exon 7 in sequence with accession number X66899) is fused to exon 2 of YY1 (nucleotide 1160 accession number NM_003403 version 3). The putative EWSR1-YY1 protein would contain the transactivation domain of EWSR1 and the DNA binding domain of YY1 and thus may act as ...
SNP discovery
... (2) the reference genome base was ambiguous at the SNP position or within 60 bases of it, (3) Another SNP was detected within 50 bases, (4) the average copy number of the SNP flanking region was more than two, (5) the Illumina quality score of either allele was less than 20, (6) the number of reads ...
... (2) the reference genome base was ambiguous at the SNP position or within 60 bases of it, (3) Another SNP was detected within 50 bases, (4) the average copy number of the SNP flanking region was more than two, (5) the Illumina quality score of either allele was less than 20, (6) the number of reads ...
CNVs vs. SNPs: Understanding Human Structural Variation in Disease
... So, in 2007, Science Magazine announced its breakthrough of the year as human genetic variation. Part of the reason for this was the fact that there were a lot of associations being made between these single nucleotide polymorphisms or SNPs with human diseases. Currently, i ...
... So, in 2007, Science Magazine announced its breakthrough of the year as human genetic variation. Part of the reason for this was the fact that there were a lot of associations being made between these single nucleotide polymorphisms or SNPs with human diseases. Currently, i ...
Spider Silk - Consortium for Mathematics and its Applications
... 3. Why are there 3 nucleotides in a codon? Why not 2? Why not 4? 4. How would you translate a sequence of 20 or 40 codons? Describe a more efficient method for translation of long codon sequences. 5. Are there other ways to depict the genetic code? Find a different image or diagram and be prepared t ...
... 3. Why are there 3 nucleotides in a codon? Why not 2? Why not 4? 4. How would you translate a sequence of 20 or 40 codons? Describe a more efficient method for translation of long codon sequences. 5. Are there other ways to depict the genetic code? Find a different image or diagram and be prepared t ...
model for Escherichia coli chromosome packaging supports
... TF regulates, the higher is its need to be expressed in higher concentrations to regulate targets located dispersedly on the chromosome. In contrast, local or dedicated TFs were found to be expressed in much lower concentrations explaining the reasons for their proximity on the chromosome to their t ...
... TF regulates, the higher is its need to be expressed in higher concentrations to regulate targets located dispersedly on the chromosome. In contrast, local or dedicated TFs were found to be expressed in much lower concentrations explaining the reasons for their proximity on the chromosome to their t ...
METHODS TO DETECT SELECTION IN POPULATIONS WITH
... just a transient phase of molecular evolution” (57). Kimura did even more in this paper. He also deduced a major role for selection by showing that the rate of amino acid substitution in hemoglobin was far lower than that predicted from reasonable estimates of the nucleotide mutation rate. He argued ...
... just a transient phase of molecular evolution” (57). Kimura did even more in this paper. He also deduced a major role for selection by showing that the rate of amino acid substitution in hemoglobin was far lower than that predicted from reasonable estimates of the nucleotide mutation rate. He argued ...
University of Groningen DNA-based asymmetric catalysis
... 1.1 Asymmetric catalysis and water 1.1.1 Asymmetry in catalysis Molecules can have different three-dimensional structures even though they have the same combinations of bonds between the atoms.1 If these molecules are non-superimposable mirror images, they are considered to be chiral, and are called ...
... 1.1 Asymmetric catalysis and water 1.1.1 Asymmetry in catalysis Molecules can have different three-dimensional structures even though they have the same combinations of bonds between the atoms.1 If these molecules are non-superimposable mirror images, they are considered to be chiral, and are called ...
Bacterial community composition in the rhizosphere of a transgenic
... separate group (data not shown) but this result was obviously triggered by the lower amount of total DNA from PCR products loaded onto the gel. Other group-A replicates did not separate out into uniform clusters. Each SSCP pro¢le generated with the use of the primer set amplifying the variable regio ...
... separate group (data not shown) but this result was obviously triggered by the lower amount of total DNA from PCR products loaded onto the gel. Other group-A replicates did not separate out into uniform clusters. Each SSCP pro¢le generated with the use of the primer set amplifying the variable regio ...
Complete genome sequence of the thermophilic Thermus sp
... of synteny. The three closest Thermus with sequenced genomes (T. thermophilus strains HB27, HB8 and T. scotoductus SA-01) were selected for the comparison. The genome of strain HB27 consists of a chromosome (1.89 Mb) and a megaplasmid (0.23 Mb). On the other hand, strain HB8 has a chromosome of 1.85 ...
... of synteny. The three closest Thermus with sequenced genomes (T. thermophilus strains HB27, HB8 and T. scotoductus SA-01) were selected for the comparison. The genome of strain HB27 consists of a chromosome (1.89 Mb) and a megaplasmid (0.23 Mb). On the other hand, strain HB8 has a chromosome of 1.85 ...
Swarm-PBC09-MEP - Data to Insight Center
... RNAs (mRNAs) which is transcribed from the genes residing on chromosomes. • EST Sequencing: Re-constructing full length of mRNA sequences for each expressed gene by means of assembling EST fragments. • EST sequencing is a standard practice for gene discovery, especially for the genomes of many organ ...
... RNAs (mRNAs) which is transcribed from the genes residing on chromosomes. • EST Sequencing: Re-constructing full length of mRNA sequences for each expressed gene by means of assembling EST fragments. • EST sequencing is a standard practice for gene discovery, especially for the genomes of many organ ...
papaya X-specific BACs monoica corresponding
... monoica were analyzed. Carica papaya is a trioecious tropical plant with very young sex chromosomes (2-3 my), the segregation of which results in male (XY), female (XX), and hermaphrodite (XYh) individuals. Close relative Vasconcellea monoica, which diverged from a shared common ancestor with papaya ...
... monoica were analyzed. Carica papaya is a trioecious tropical plant with very young sex chromosomes (2-3 my), the segregation of which results in male (XY), female (XX), and hermaphrodite (XYh) individuals. Close relative Vasconcellea monoica, which diverged from a shared common ancestor with papaya ...
EXTENDED CONCEPT OF KNOWLEDGE FOR EVOLUTIONARY
... accept that genes or DNA play a central role in evolution. As Dawkins has noticed, genes, identified with pieces of DNA-strings, are 'good replicators'. Replicators are defined to be entities with three characteristics: 'fidelity, longevity, and fecundity' (Dawkins, 1976). However, mere material of ...
... accept that genes or DNA play a central role in evolution. As Dawkins has noticed, genes, identified with pieces of DNA-strings, are 'good replicators'. Replicators are defined to be entities with three characteristics: 'fidelity, longevity, and fecundity' (Dawkins, 1976). However, mere material of ...
The presence of two UvrB subunits in the UvrAB complex ensures
... signi®cant average volume. Since these unwrapped complexes are expected to have lost the ATP molecule, we decided to analyse these complexes further by determining the volumes of UvrB±DNA complexes that were isolated by washing in the absence of ATP. As expected, no wrapped complexes were observed a ...
... signi®cant average volume. Since these unwrapped complexes are expected to have lost the ATP molecule, we decided to analyse these complexes further by determining the volumes of UvrB±DNA complexes that were isolated by washing in the absence of ATP. As expected, no wrapped complexes were observed a ...
Agarose Gel Electrophoresis
... systems can be set up by purchasing and assembling the individual components (e.g., camera, film holder, filters, and UV transilluminator). Alternatively, complete photography systems are commercially available (Bio-Rad, UVP). A major disadvantage of traditional photography is the high cost of film. ...
... systems can be set up by purchasing and assembling the individual components (e.g., camera, film holder, filters, and UV transilluminator). Alternatively, complete photography systems are commercially available (Bio-Rad, UVP). A major disadvantage of traditional photography is the high cost of film. ...
Molecular cloning and functional characterisation of a glucose
... PDR3, which are present in HXT9 and HXT11 of S. cerevisiae, were absent in CaHGT1 promoter. 3.3. CaHGT1 could complement the glucose transport defect when expressed in S. cerevisiae In order to check the functionality of the cloned putative glucose transporter, the glucose uptake-de¢cient strain RE7 ...
... PDR3, which are present in HXT9 and HXT11 of S. cerevisiae, were absent in CaHGT1 promoter. 3.3. CaHGT1 could complement the glucose transport defect when expressed in S. cerevisiae In order to check the functionality of the cloned putative glucose transporter, the glucose uptake-de¢cient strain RE7 ...
Towards the development of standardized methods for comparison
... compared with all others. Hence, at the current state of development of structure comparison techniques, it is advisable to use several programs in parallel and to choose the optimal alignment in the way reported here. Availability and implementation: The computer software that implement the method ...
... compared with all others. Hence, at the current state of development of structure comparison techniques, it is advisable to use several programs in parallel and to choose the optimal alignment in the way reported here. Availability and implementation: The computer software that implement the method ...
A DNA Polymerase ε Mutant That Specifically Causes 1
... 1997; Burgers 1998). We have developed a novel mutation detection system, based on interactions with exo1 mutants, to identify functions of Polε other than proofreading that influence genome stability. We have identified a unique DNA polymerase mutator with defects that are not due to a change in pr ...
... 1997; Burgers 1998). We have developed a novel mutation detection system, based on interactions with exo1 mutants, to identify functions of Polε other than proofreading that influence genome stability. We have identified a unique DNA polymerase mutator with defects that are not due to a change in pr ...
during the Somatic Hypermutation Process Trends in Antibody
... The L and H chain matching is handled using a similar exhaustive procedure. In each case the V genes are matched first near the N terminus of the sequence, and the best match is retained. The unmatched portion of the sequence is then extracted, and the best J gene match is found using a similar proc ...
... The L and H chain matching is handled using a similar exhaustive procedure. In each case the V genes are matched first near the N terminus of the sequence, and the best match is retained. The unmatched portion of the sequence is then extracted, and the best J gene match is found using a similar proc ...