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Lecture 6 Gene expression: microarray and deep sequencing
Lecture 6 Gene expression: microarray and deep sequencing

Slide 1
Slide 1

... Sequences of 3 bases in RNA code for a single amino acid There are 64 possible ‘triplets’ that can be formed from the 4 different bases, but there are only 20 amino acids (AA) In most cases, more than one type of triplet codes for a given AA For example, CAA and CAG both code for the same AA, glutam ...
Bioinformatics V - Isfahan University of Medical Sciences
Bioinformatics V - Isfahan University of Medical Sciences

... What is BLAST? BLAST® (Basic Local Alignment Search Tool) is a set of similarity search programs designed to explore all of the available sequence databases regardless of whether the query is protein or DNA. “local” means it searches and aligns sequence segments, rather than align the entire seque ...
*J5JT*_§JJU: ~$f4~*
*J5JT*_§JJU: ~$f4~*

... longer able to lead independent lives because most genes originally present on their chromosome have moved to the nuclear genome. Which phenomenon accounts for the movement of these genes? A) conjugation B) plasmolysis C) translation D) horizontal gene transfer ...
Unit topics - Kevan Kruger
Unit topics - Kevan Kruger

... ...
Chapter 8: Genetic Epidemiology
Chapter 8: Genetic Epidemiology

... Chromosome structure • 46 chromosomes are present in each human cell. • Chromosomes are made up of DNA and histones. ...
Word Definition 1 non-Mendelian genetics rules for inheritance that
Word Definition 1 non-Mendelian genetics rules for inheritance that

... mucus in their lungs, which makes it difficult for them to breathe an international effort to sequence all 3 billion bases that make up our DNA 10 Human Genome Project and to identify within this code more than 20,000 human genes 11 genome all the DNA in one cell 12 pedigree a family tree that track ...
WHO and patenting of genes
WHO and patenting of genes

... complex interactions between their genetic make-up, their environment and the long history of the milieu in which they are raised Health and Biomedicine: It is likely that future research into diseasesusceptibility genes will help us to understand the mechanisms…, it will allow treatment to be tailo ...
human_genome_sum.pdf
human_genome_sum.pdf

... imagine in advance. For example, studying the sequence of the human genome is beginning to lead to an understanding of how non-coding sequences may be regulating gene expression at several different levels. ...
Panel Topics
Panel Topics

... genetic (SNP, CNV, somatic mutation) and clinical information.  How can expression (phenotype) and genotype information be integrated?  What kind of new information can be derived from the integration?  How can clinical information (treatment, survival, pathology) be utilized? ...
Test Study Guide
Test Study Guide

... How did Hershey and Chase know that it was the DNA that had infected the bacterial cells in their experiment?  Watson and Crick – What did Watson and Crick create with the model of DNA?  Franklin – ...
Gene!
Gene!

... Thie mutant was originally produced by the action of proflavins. We@ have previously argued that acridines such aa pro5vin act as mutagens because they add or dslsts a base or bases. The most striking evidence in favour of this is that mutants produced by a&dines are seldom ‘leaky’ ; they are almost ...
Variation, DNA and Protein Synthesis
Variation, DNA and Protein Synthesis

... Explain how amino acids are assembled in the correct order determined by the codons on mRNA Understand a stop codon on mRNA signals the release of the protein Understand that the protein folds into its functional ...
Cow DNA: How DNA Controls the Workings of the Cell
Cow DNA: How DNA Controls the Workings of the Cell

... Below are two partial sequences of DNA bases (shown for only one strand of DNA) Sequence 1 is from a human and sequence 2 is from a cow. In both humans and cows, this sequence is part of a set of instructions for controlling a bodily function. In this case, the sequence contains the gene to make the ...
Genetics
Genetics

... Relate the concept of the gene to the sequences of nucleotides in DNA Sequence the steps involving protein synthesis Categorize the different kinds of mutations that can occur in DNA Compare the effects of different kinds of mutations on cells and organisms. ...
What is Bioinformatics? - UNC
What is Bioinformatics? - UNC

... University of North Carolina-Chapel Hill [email protected] ...
Genetic Engineering
Genetic Engineering

... The bacteria then infects other cells, giving them the gene (bacteria cell is called a transgenic organism) ...
Genetic Engineering
Genetic Engineering

... The bacteria then infects other cells, giving them the gene (bacteria cell is called a transgenic organism) ...
Italian Association for Cancer Research NETWORK OF
Italian Association for Cancer Research NETWORK OF

... The overall goals of the Network are: (a) to create a network of researchers involved in the identification of relevant interactions between genes and the environment through studies of molecular epidemiology in Italy; (b) to rationalize and improve the quality of laboratory measurements by referrin ...
GenomeWeb Stanford Team Shows How Long Reads Can
GenomeWeb Stanford Team Shows How Long Reads Can

Ensembl - Internet Database Lab.
Ensembl - Internet Database Lab.

... Proteins aligned Unigene clusters aligned cDNAs aligned ...
Using DNA Subway in the Classroom Red Line Lesson
Using DNA Subway in the Classroom Red Line Lesson

... First, use DNA subway to show how we can reveal features of a sequence. Create a project using a sample sequence. Once students have mastery, they can come back and create their own projects using real data. ...
REPLICATION, TRANSCRIPTION, TRANSLATION TAKS
REPLICATION, TRANSCRIPTION, TRANSLATION TAKS

... 14 Part of a DNA strand is represented in the diagram above. In order for DNA to replicate, the strand must separate at which of the following locations? F Between every phosphate-sugar pair G Between the eight sugar-base pairs H* Between the four nitrogenous base pairs J Between any two chemical bo ...
DrMoran
DrMoran

... make up genes.  Genes make different things for our body.  They are packaged up into chromosomes  Chromosomes are like a big recipe box for our bodies and DNA is the recipe! ...
Plant DNA - The uniqueness of DNA
Plant DNA - The uniqueness of DNA

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Genomics

Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes (the complete set of DNA within a single cell of an organism). Advances in genomics have triggered a revolution in discovery-based research to understand even the most complex biological systems such as the brain. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome's networks.
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