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... Worldwide, the heterosexual route is the most common mode of sexual transmission of HIV-‐1 and women are particularly susceptible to this infection. After penetration of the mucosal epithelium HIV-‐1 interacts ...
... Worldwide, the heterosexual route is the most common mode of sexual transmission of HIV-‐1 and women are particularly susceptible to this infection. After penetration of the mucosal epithelium HIV-‐1 interacts ...
The Nicotiana tabacum genome encodes two cytoplasmic
... KpnI (three bands). Copy number reconstruction with DNA digested with EcoRI indicates that there is approximately one gene copy per haploid genome. The band patterns and intensity of hybridization can be consistently interpreted to give a total per genome of two genes which are homologous to thiored ...
... KpnI (three bands). Copy number reconstruction with DNA digested with EcoRI indicates that there is approximately one gene copy per haploid genome. The band patterns and intensity of hybridization can be consistently interpreted to give a total per genome of two genes which are homologous to thiored ...
Design-O-Saur - Beyond Benign
... Decode provided information to build a genetically unique dinosaur. Understand that this is a model that could be used to look at human genetics Understand gene sequences and the results of these sequences Materials: Clay – model magic works very well Student sheets Time needed: 1 x 45-60 ...
... Decode provided information to build a genetically unique dinosaur. Understand that this is a model that could be used to look at human genetics Understand gene sequences and the results of these sequences Materials: Clay – model magic works very well Student sheets Time needed: 1 x 45-60 ...
Global measles elimination - Measles and Rubella Initiative
... receptors for MV. The two identified receptors are CD46 and CD150 (also known as SLAM). CD46 is a complement regulatory molecule expressed on all nucleated cells in humans. SLAM (signalling lymphocyte activation molecule) is expressed on activated T and B lymphocytes and antigen-presenting cells. Th ...
... receptors for MV. The two identified receptors are CD46 and CD150 (also known as SLAM). CD46 is a complement regulatory molecule expressed on all nucleated cells in humans. SLAM (signalling lymphocyte activation molecule) is expressed on activated T and B lymphocytes and antigen-presenting cells. Th ...
Autoimmunity to glomerular antigens in
... immune complexes in glomeruli. In IgA nephropathy, increased IgA antibody levels to several ubiquitous food antigens [37-391 and autoantigens [12,28-301 have been reported. Several authors have suggested a specific role for gliadin in IgA nephropathy [40,41], but this has not been confirmed by other ...
... immune complexes in glomeruli. In IgA nephropathy, increased IgA antibody levels to several ubiquitous food antigens [37-391 and autoantigens [12,28-301 have been reported. Several authors have suggested a specific role for gliadin in IgA nephropathy [40,41], but this has not been confirmed by other ...
Two Waves of Nuclear Factor κB Recruitment to Target Promoters
... quence of the NF-B site in MIP-2 (a gene with immediate NF-B recruitment) is identical to the sequence of one of the two NF-B sites in MCP-1 (a gene with delayed NF-B recruitment). Overall, this suggests that the observed differences in the kinetic of NF-B recruitment to the genes under investi ...
... quence of the NF-B site in MIP-2 (a gene with immediate NF-B recruitment) is identical to the sequence of one of the two NF-B sites in MCP-1 (a gene with delayed NF-B recruitment). Overall, this suggests that the observed differences in the kinetic of NF-B recruitment to the genes under investi ...
Document
... the initial stages of infection. Therefore, in immunocompetent individuals, R. equi induces a protective response that starts from the innate immune system. The effect of R. equi on dendritic cells has been poorly studied in vivo. In vitro, Darrah et al.42 showed that purified R. equi virulence-asso ...
... the initial stages of infection. Therefore, in immunocompetent individuals, R. equi induces a protective response that starts from the innate immune system. The effect of R. equi on dendritic cells has been poorly studied in vivo. In vitro, Darrah et al.42 showed that purified R. equi virulence-asso ...
Fusobacterium nucleatum Alters Atherosclerosis Risk
... mice. ApoEnull mice (n = 23) were orally infected with F. nucleatum ATCC 49256 and euthanized at 12 and 24 weeks. Periodontal disease assessments including F. nucleatum oral colonization, gingival inflammation, immune response, intrabony defects, and alveolar bone resorption were evaluated. Systemic ...
... mice. ApoEnull mice (n = 23) were orally infected with F. nucleatum ATCC 49256 and euthanized at 12 and 24 weeks. Periodontal disease assessments including F. nucleatum oral colonization, gingival inflammation, immune response, intrabony defects, and alveolar bone resorption were evaluated. Systemic ...
A Comparative Study on the Recovery of EcoRI Endonuclease from
... by phosphocellulose and hydroxyapatite chromatographies respectively. They have obtained 500 mg of enzyme per kg cell paste with a recovery of 47%. The specific activity of the EcoRI endonuclease was reported to be 4.5x104 U/mg protein. It can be calculated that Cheng et al.2 have obtained approxima ...
... by phosphocellulose and hydroxyapatite chromatographies respectively. They have obtained 500 mg of enzyme per kg cell paste with a recovery of 47%. The specific activity of the EcoRI endonuclease was reported to be 4.5x104 U/mg protein. It can be calculated that Cheng et al.2 have obtained approxima ...
Virus-Encoded microRNAs: An Overview and a Look to the
... Cancer Research and Prevention in Texas grant, a Burroughs Wellcome Investigators in Pathogenesis Award, and a UT Austin Institute for Cellular and Molecular Biology fellowship to CSS. Additional support is provided by a University of Texas Graduate School William Powers, Jr. Graduate Fellowship to ...
... Cancer Research and Prevention in Texas grant, a Burroughs Wellcome Investigators in Pathogenesis Award, and a UT Austin Institute for Cellular and Molecular Biology fellowship to CSS. Additional support is provided by a University of Texas Graduate School William Powers, Jr. Graduate Fellowship to ...
Epigenetics & Chromatin Xist through transcriptional control of Dnmt3a
... is expressed in XX cells, and that the single Xist allele in XY cells remains repressed. The classical model for this process invokes the presence of a blocking factor present at limiting levels such that only a single Xist allele is blocked in each cell [21]. More recently evidence has emerged that ...
... is expressed in XX cells, and that the single Xist allele in XY cells remains repressed. The classical model for this process invokes the presence of a blocking factor present at limiting levels such that only a single Xist allele is blocked in each cell [21]. More recently evidence has emerged that ...
Fig. - DIGITAL.CSIC, el repositorio institucional
... phases on the structure and solvent properties of water25, creating distinct environments commonly leading to unequal partition of solutes (small organic molecules, proteins, nucleic acids, RNPs, etc.) which can be enhanced by, but does not generally require, their interactions with phase forming ma ...
... phases on the structure and solvent properties of water25, creating distinct environments commonly leading to unequal partition of solutes (small organic molecules, proteins, nucleic acids, RNPs, etc.) which can be enhanced by, but does not generally require, their interactions with phase forming ma ...
Expression and characterization of 1
... demonstrated that plants treated with ACCD containing P. putida UW4 (as opposed to a knockout mutant) display down-regulation of stress and defense genes but upregulation of growth-associated genes [17]. Despite the biological studies on the effects P. putida UW4 has on plant growth, little is known ...
... demonstrated that plants treated with ACCD containing P. putida UW4 (as opposed to a knockout mutant) display down-regulation of stress and defense genes but upregulation of growth-associated genes [17]. Despite the biological studies on the effects P. putida UW4 has on plant growth, little is known ...
Single-stranded heteroduplex intermediates in l Red homologous
... Background: The Red proteins of lambda phage mediate probably the simplest and most efficient homologous recombination reactions yet described. However the mechanism of dsDNA recombination remains undefined. Results: Here we show that the Red proteins can act via full length single stranded intermed ...
... Background: The Red proteins of lambda phage mediate probably the simplest and most efficient homologous recombination reactions yet described. However the mechanism of dsDNA recombination remains undefined. Results: Here we show that the Red proteins can act via full length single stranded intermed ...
Epitope Specificity of Anti-Citrullinated Protein Antibodies
... In this process, an increase in PAD2 and PAD4 enzyme levels is often observed [7,12]. The role of the inflammatory process [11]. of PAD in the onset of RA has been examined, and recently, a model for PAD infiltration into the In this process, an increase in PAD2 and PAD4 enzyme levels is often obs ...
... In this process, an increase in PAD2 and PAD4 enzyme levels is often observed [7,12]. The role of the inflammatory process [11]. of PAD in the onset of RA has been examined, and recently, a model for PAD infiltration into the In this process, an increase in PAD2 and PAD4 enzyme levels is often obs ...
Licentiate thesis from the Department of Immunology,
... the adaptive immune response are activated by co-stimulatory molecules that are induced on cells of the innate immune system during their interaction with microorganisms. The cytokines produced during these early phases also have an important role in stimulating the subsequent adaptive immune respon ...
... the adaptive immune response are activated by co-stimulatory molecules that are induced on cells of the innate immune system during their interaction with microorganisms. The cytokines produced during these early phases also have an important role in stimulating the subsequent adaptive immune respon ...
Chance and Necessity in Arthur Peacocke`s Scientific Work
... determined that DNA was the hereditary (genetic) material, and the fact that DNA is the molecular bases of heredity peaked Peacocke’s interest in this molecule (Drysdale and Peacocke 1961), although exactly how DNA gave rise to proteins in the cell, how DNA was structured and ordered, and how it fun ...
... determined that DNA was the hereditary (genetic) material, and the fact that DNA is the molecular bases of heredity peaked Peacocke’s interest in this molecule (Drysdale and Peacocke 1961), although exactly how DNA gave rise to proteins in the cell, how DNA was structured and ordered, and how it fun ...
Insoluble and soluble immune complexes activate neutrophils by
... eutrophils have a crucial role in host protection against bacterial and fungal infections and thus possess a battery of cytotoxic enzymes and associated pathways to perform this important function.1–3 During phagocytosis, these cytotoxic processes are activated and delivered within intracellular pha ...
... eutrophils have a crucial role in host protection against bacterial and fungal infections and thus possess a battery of cytotoxic enzymes and associated pathways to perform this important function.1–3 During phagocytosis, these cytotoxic processes are activated and delivered within intracellular pha ...
CXCL10 Inhibits Viral Replication Through Recruitment of Natural
... control littermates (Figure 3a). The number of infiltrations was age-dependent, with the highest in older Tg mice, but barely any in 4-week-old mice. We used real-time qRT-PCR to determine the levels of CD45, CD3, CD4, CD8, and natural cytotoxicity receptor (NCR). As shown in Figure 3b, the levels o ...
... control littermates (Figure 3a). The number of infiltrations was age-dependent, with the highest in older Tg mice, but barely any in 4-week-old mice. We used real-time qRT-PCR to determine the levels of CD45, CD3, CD4, CD8, and natural cytotoxicity receptor (NCR). As shown in Figure 3b, the levels o ...
Distinct and Separable Roles of the Complement System in Factor H
... analogy to erythrocyte CR1, we considered it possible that platelets are endowed with Cfh upon exit from the bone marrow. To investigate this, we cultured megakaryocytes from normal C57BL/6 mice. These had the expected arborizing processes that released into the culture supernatant a continuous supp ...
... analogy to erythrocyte CR1, we considered it possible that platelets are endowed with Cfh upon exit from the bone marrow. To investigate this, we cultured megakaryocytes from normal C57BL/6 mice. These had the expected arborizing processes that released into the culture supernatant a continuous supp ...
DNA vaccination
DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.