Heat Shock Proteins-an
... with antigen presenting cells including human dendritic cells (DC) and monocytes resulted in potent chaperokine activity. Further studies by the same group demonstrated that parvovirus-mediated cell killing enhances tumor immunogenicity by Hsp72 release and contributes to the anti-tumor effect of pa ...
... with antigen presenting cells including human dendritic cells (DC) and monocytes resulted in potent chaperokine activity. Further studies by the same group demonstrated that parvovirus-mediated cell killing enhances tumor immunogenicity by Hsp72 release and contributes to the anti-tumor effect of pa ...
Real-time PCR-based detection of Bordetella pertussis and
... sequence are considered the most efficient diagnostic tools for pertussis in children .7 years, adolescents and adults (André et al., 2008). However, the use of serology for pertussis diagnosis in younger children is less useful due to recent vaccination, and the lack of pertussis toxin antibody re ...
... sequence are considered the most efficient diagnostic tools for pertussis in children .7 years, adolescents and adults (André et al., 2008). However, the use of serology for pertussis diagnosis in younger children is less useful due to recent vaccination, and the lack of pertussis toxin antibody re ...
1 - IPPC
... turn brown in apples and dark brown to black in pears, but remain attached to the tree for some time. Upon infection young fruitlets turn brown but also remain attached to the tree. Immature fruit lesions appear oily or water-soaked, become brown to black, and often ooze droplets of bacterial exudat ...
... turn brown in apples and dark brown to black in pears, but remain attached to the tree for some time. Upon infection young fruitlets turn brown but also remain attached to the tree. Immature fruit lesions appear oily or water-soaked, become brown to black, and often ooze droplets of bacterial exudat ...
Full text - Universiteit Leiden
... cardiovascular events are associated with myocardial infarction and stroke as a result of a ruptured plaque and a subsequent thrombotic event (Figure 1.1C).32, 33 Plaque rupture is the final outcome of plaque destabilization. During lesion development activated macrophages, T cells and other immune ...
... cardiovascular events are associated with myocardial infarction and stroke as a result of a ruptured plaque and a subsequent thrombotic event (Figure 1.1C).32, 33 Plaque rupture is the final outcome of plaque destabilization. During lesion development activated macrophages, T cells and other immune ...
NO sensing by FNR: regulation of the Escherichia coli NO
... the ¯avohaemoglobin-encoding gene of E.coli, hmp, is upregulated by NO and RNS; this appears not to involve SoxRS (Poole et al., 1996). We have reported (MembrilloHernaÂndez et al., 1998) a mechanism of hmp gene regulation that involves interaction between S-nitrosothiols and Hcy. Intracellular Hcy ...
... the ¯avohaemoglobin-encoding gene of E.coli, hmp, is upregulated by NO and RNS; this appears not to involve SoxRS (Poole et al., 1996). We have reported (MembrilloHernaÂndez et al., 1998) a mechanism of hmp gene regulation that involves interaction between S-nitrosothiols and Hcy. Intracellular Hcy ...
The Innate and Adaptive Immune Response to
... the burden of disease. Due to differences between strains and confounding data of measles stocks contaminated with defective interfering RNA particles, the immune response to measles virus infection has not been well defined. Furthermore, the mechanism by which vitamin A protects against severe meas ...
... the burden of disease. Due to differences between strains and confounding data of measles stocks contaminated with defective interfering RNA particles, the immune response to measles virus infection has not been well defined. Furthermore, the mechanism by which vitamin A protects against severe meas ...
Capra Colostrum
... milk, providing the two most important components for overall health—immune and growth factors. It has shown to be easily tolerated even by those with the most compromised immune systems, including victims of chemical sensitivities. Colostrum from Vitomega BV comes from goats that are never fed synt ...
... milk, providing the two most important components for overall health—immune and growth factors. It has shown to be easily tolerated even by those with the most compromised immune systems, including victims of chemical sensitivities. Colostrum from Vitomega BV comes from goats that are never fed synt ...
Monoclonal Antibodies for Therapeutic Use: Specific Characteristics
... The use of animal models during the development of MoAb is difficult due to the between-species differences of the “partners” of the MoAb, i.e. target antigen and immune effectors (including FcγR receptors).[19] MoAb do not usually recognise target antigens in the mouse. These models therefore requi ...
... The use of animal models during the development of MoAb is difficult due to the between-species differences of the “partners” of the MoAb, i.e. target antigen and immune effectors (including FcγR receptors).[19] MoAb do not usually recognise target antigens in the mouse. These models therefore requi ...
Regulatory Motifs in DNA Sequences
... • Examine frequencies of l-tuples, combinations of 2 symbols, 3 symbols, etc. • “The” is the most frequent 3-tuple in English and “;48” is the most frequent 3tuple in the encrypted text • Make inferences of unknown symbols by examining other frequent l-tuples ...
... • Examine frequencies of l-tuples, combinations of 2 symbols, 3 symbols, etc. • “The” is the most frequent 3-tuple in English and “;48” is the most frequent 3tuple in the encrypted text • Make inferences of unknown symbols by examining other frequent l-tuples ...
Notes for Chaper 4 of the Jones/Pevzer book
... • Nucleotides in motifs encode for a message in the “genetic” language. Symbols in “The Gold Bug” encode for a message in English • In order to solve the problem, we analyze the frequencies of patterns in DNA/Gold Bug message. • Knowledge of established regulatory motifs makes the Motif Finding prob ...
... • Nucleotides in motifs encode for a message in the “genetic” language. Symbols in “The Gold Bug” encode for a message in English • In order to solve the problem, we analyze the frequencies of patterns in DNA/Gold Bug message. • Knowledge of established regulatory motifs makes the Motif Finding prob ...
24. Lymphatic System
... the venous circulation. If this excess fluid were not removed, body tissues would swell, a condition called edema (e-dē ́mă; oidema = a swelling). Further, this excess fluid would accumulate outside the bloodstream, causing blood levels to drop precipitously. Thus, the lymphatic system prevents i ...
... the venous circulation. If this excess fluid were not removed, body tissues would swell, a condition called edema (e-dē ́mă; oidema = a swelling). Further, this excess fluid would accumulate outside the bloodstream, causing blood levels to drop precipitously. Thus, the lymphatic system prevents i ...
Xq28 duplications
... like other X chromosome anomalies, also varies if the child is a boy or a girl. In general, duplication of Xq28 has a milder effect, or no obvious effect in girls since girls have two X chromosomes and the chromosome with the duplication is usually the one that is switched off. As a result, the extr ...
... like other X chromosome anomalies, also varies if the child is a boy or a girl. In general, duplication of Xq28 has a milder effect, or no obvious effect in girls since girls have two X chromosomes and the chromosome with the duplication is usually the one that is switched off. As a result, the extr ...
Humoral and cellular immune responses to Helicobacter
... Many therapeutic and prophylactic vaccine candidates against H. pylori have been evaluated in experimental animals and several of these studies have suggested that it is possible to induce protective immunity by vaccination (38, 104, 116, 134). The main candidates so far are the virulence factors of ...
... Many therapeutic and prophylactic vaccine candidates against H. pylori have been evaluated in experimental animals and several of these studies have suggested that it is possible to induce protective immunity by vaccination (38, 104, 116, 134). The main candidates so far are the virulence factors of ...
Probiotic characteristics of Lactobacillus acidophilus and
... Effect of A) L. acidophilus L10 and B) L. paracasei L26 on immunoglobulin (Ig)-A producing cells in the small intestine of mice. Effect of orally administered L. acidophilus L10 or L. paracasei L26 on A) interleukin (IL)-10 and B) interferon (IFN)- cytokine producing cells in the small intestine of ...
... Effect of A) L. acidophilus L10 and B) L. paracasei L26 on immunoglobulin (Ig)-A producing cells in the small intestine of mice. Effect of orally administered L. acidophilus L10 or L. paracasei L26 on A) interleukin (IL)-10 and B) interferon (IFN)- cytokine producing cells in the small intestine of ...
Vaccinia virus protein A46R targets multiple Toll-like
... mice (2–5). Many but not all of these receptors have been assigned a role in the initial detection of, and response to, specific pathogen-associated molecules (PAMs). In macrophages and neutrophils, this drives innate immune responses, such as inflammation and induction of microbicidal activity, whe ...
... mice (2–5). Many but not all of these receptors have been assigned a role in the initial detection of, and response to, specific pathogen-associated molecules (PAMs). In macrophages and neutrophils, this drives innate immune responses, such as inflammation and induction of microbicidal activity, whe ...
Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics
... Variable breakpoints on both genes. Abnormal protein ...
... Variable breakpoints on both genes. Abnormal protein ...
Abstract Book - 27th Annual Meeting of the Society for Virology
... The family of Picornaviruses contains many important pathogens for humans and animals. Well-known human pathogens are poliovirus, enterovirus-A71, coxsackievirus, enterovirus-D68, and rhinovirus, all of which belong to the Enterovirus genus. Vaccines are available against poliovirus and -since recen ...
... The family of Picornaviruses contains many important pathogens for humans and animals. Well-known human pathogens are poliovirus, enterovirus-A71, coxsackievirus, enterovirus-D68, and rhinovirus, all of which belong to the Enterovirus genus. Vaccines are available against poliovirus and -since recen ...
Early cytokine release in response to live largely complement independent
... response. The innate immune system is the first line of defence that the spirochetes encounter when entering the body. These reactions are the key determinants of the magnitude and quality of the early immune response, and they subsequently initiate and form the adaptive immune response [7]. The com ...
... response. The innate immune system is the first line of defence that the spirochetes encounter when entering the body. These reactions are the key determinants of the magnitude and quality of the early immune response, and they subsequently initiate and form the adaptive immune response [7]. The com ...
IMMUNOREACTIONS INVOLVING PLATELETS. VI. REACTIONS OF
... serum could be estimated by determining the smallest amount of serum that would inhibit C' fixation by a given amount of anti-PlA, with a given number of platelets. For instance, as little as 0.04 ml of Mother K's serum completely prevented C' fixation by 107 PlA(1,1) platelets with 4 U of anti-PlAl ...
... serum could be estimated by determining the smallest amount of serum that would inhibit C' fixation by a given amount of anti-PlA, with a given number of platelets. For instance, as little as 0.04 ml of Mother K's serum completely prevented C' fixation by 107 PlA(1,1) platelets with 4 U of anti-PlAl ...
Optimal estimation of diffusion coefficients from single
... measure diffusion coefficients in the range 0.1–0.5 μm2 /s. We show that the DNA fluctuations induce a bias in the estimates of diffusion coefficients of up to 0.25 μm2 /s; i.e., we may overestimate diffusion coefficients by several times their actual values if the fluctuations are not taken into ac ...
... measure diffusion coefficients in the range 0.1–0.5 μm2 /s. We show that the DNA fluctuations induce a bias in the estimates of diffusion coefficients of up to 0.25 μm2 /s; i.e., we may overestimate diffusion coefficients by several times their actual values if the fluctuations are not taken into ac ...
Puffs and PCR: the in vivo dynamics of early gene
... of the salivary gland and showed once more that although many early puffs were common to the two tissues there were differences in their response which might find their counterparts at the molecular level. This idea has been developed in the tissue coordination model (Burtis et al., 1990; Thummel et ...
... of the salivary gland and showed once more that although many early puffs were common to the two tissues there were differences in their response which might find their counterparts at the molecular level. This idea has been developed in the tissue coordination model (Burtis et al., 1990; Thummel et ...
Control of DNA excision efficiency in Paramecium
... micronuclei undergo meiosis, whereas the macronuclei degenerate. The fusion of two gametic nuclei produces a zygotic nucleus. This nucleus divides twice and the daughter nuclei then differentiate into a micronucleus or a macronucleus. In the second case, the whole genome is processed through chromos ...
... micronuclei undergo meiosis, whereas the macronuclei degenerate. The fusion of two gametic nuclei produces a zygotic nucleus. This nucleus divides twice and the daughter nuclei then differentiate into a micronucleus or a macronucleus. In the second case, the whole genome is processed through chromos ...
Modulation of immune responses by the tumor suppressor p53
... to p53, depending on stimulus and cell type. p53 can increase transcription of several cytokines involved in innate immunity including colony-stimulating factor 1 (CSF1) and monocyte chemotactic protein (MCP1), chemokine CXC motif ligand (CXCL1) and interleukin 15 (IL-15) that attract macrophages, n ...
... to p53, depending on stimulus and cell type. p53 can increase transcription of several cytokines involved in innate immunity including colony-stimulating factor 1 (CSF1) and monocyte chemotactic protein (MCP1), chemokine CXC motif ligand (CXCL1) and interleukin 15 (IL-15) that attract macrophages, n ...
Antibodies to Chlamydia trachomatis heat shock proteins in women
... elicited by infections by either C. trachomatis or C. pneumoniae. In the whole study group, including patients and controls, there was a good correlation between LPS-IgG antibodies and MIF antibodies to C. trachomatis (rs 5 0.67, P , 0.001 Spearman’s correlation) but a poor correlation to C. pneumon ...
... elicited by infections by either C. trachomatis or C. pneumoniae. In the whole study group, including patients and controls, there was a good correlation between LPS-IgG antibodies and MIF antibodies to C. trachomatis (rs 5 0.67, P , 0.001 Spearman’s correlation) but a poor correlation to C. pneumon ...
DNA vaccination
DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.