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Epstein-Barr Virus
Epstein-Barr Virus

Part II: Recombinant DNA Technology
Part II: Recombinant DNA Technology

... Type III enzymes cleave at sites a short distance from recognition site; require ATP (but doesn't hydrolyse it); S-adenosyl-L-methionine stimulates reaction but is not required; exist as part of a complex with a modification methylase . ...
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Document

... suppression of antigen specific proliferation in vitro). Look for monoclonal antibodies that modulate a function (eg. same assay). ...
Immunity - McCarter Anatomy & Physiology
Immunity - McCarter Anatomy & Physiology

... Provide a specific immune response to infectious diseases. 2 types: - T-cells –mature in thymus - B-cells mature in bone marrow then are found in lymph nodes and spleen ...
Genetic Engineering
Genetic Engineering

... Foreign DNA is first joined to a small, circular DNA molecule known as a plasmid. Plasmids are found naturally in some bacteria and have been very useful for DNA transfer. The plasmid has a genetic marker —a gene that makes it possible to distinguish bacteria that carry the plasmid (and the foreign ...
Genetics of Immunity
Genetics of Immunity

... against that pathogen • Protection of having a previous attack without actually having the risk • Once some diseases have been removed with vaccines there is no longer any need to administer them: ...
Genetics of Immunity
Genetics of Immunity

... against that pathogen • Protection of having a previous attack without actually having the risk • Once some diseases have been removed with vaccines there is no longer any need to administer them: ...
Leukaemia Section t(12;22)(p13;q11-12) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(12;22)(p13;q11-12) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... Glutamine and prolin rich protein; widely expressed; transcriptional regulator. ...
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File

... The PCR process usually consists of a series of twenty to thirty-five cycles. Each cycle consists of three steps. Step 1: Denaturing temperature is raised to 94-96°C to break hydrogen bonds Step 2: Annealing temperature is lowered to 56°C to allow primers to attach to the target sequence Step 3: Elo ...
Chromosome Contact Matrices
Chromosome Contact Matrices

... global optimum, provided that the data is consistent with the compartment model For every compartment run the method recursively, on re-normalized sub-matrix The process naturally stops when all vectors in the compartment have positive correlation Works in polynomial time, while other approaches to ...
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ppt lecture

... compensates for genetic mutations that produce destructive proteins Main strategies involved are 1) short stretches of synthetic DNA that target the mRNA transcripts of abnormal proteins preventing its translation OR small RNA molecules (siRNA) used to degrade aberrant RNA transcripts ...
IMMUNISATION: HOW DOES IT WORK? File
IMMUNISATION: HOW DOES IT WORK? File

... system and how it may respond to vaccines • Gain an insight into the composition of vaccines and the implications this has ...
Immune Practice Test
Immune Practice Test

... The first line of defense against pathogens is to a) block pathogen from entering the body. b) kill infected cells. c) send signals to increase immune cell formation. d) kill the pathogen. ...
thromboplastin - myrnafoxsciencespot
thromboplastin - myrnafoxsciencespot

... The Second Line of Defence… Phagocytosis  Ingestion of invading microbes by Leukocytes (WBCs)  When invaders penetrate the skin special WBCs called monocytes move from the blood into tissues, where they become MACROPHAGES Inflammatory Response  A localized, nonspecific response triggered when ti ...
Biology UNIT 2 Heredity: Inheritance and Variation of traits Big Ideas
Biology UNIT 2 Heredity: Inheritance and Variation of traits Big Ideas

... molecules. Genes are regions in the DNA that contain the instructions that code for the formation of proteins. (secondary to HS-LS3-1) (Note: This Disciplinary Core Idea is also addressed by HS-LS1-1.) LS3.A: Inheritance of Traits  Each chromosome consists of a single very long DNA molecule, and ea ...
Timeline of immunology
Timeline of immunology

... 1985 Tonegawa, Hood et al., Identification of immunoglobulin genes, somatic generation of Ig variable regions 1985-onwards - Rapid identification of genes for immune cells, antibodies, cytokines and other immunological structures 1987- Structure of MHC I defined (Wiley and Strominger) 1986 - Hepatit ...
Immunology: Specific Immunity
Immunology: Specific Immunity

... Dual Nature of the immune system • Humoral and cell mediated – Humoral refers to body fluids • Specifically antibodies: protein molecules dissolved in blood, body fluids, and secretions. • B lymphocytes are the source of antibodies – Cell mediated refers to the direct involvement of cells to attack ...
dipaimmunesystem - Dr. Brahmbhatt`s Class Handouts
dipaimmunesystem - Dr. Brahmbhatt`s Class Handouts

... This is a specific response to a specific pathogen/antigen. • B-cell lymphocytes are responsible for humoral immunity, which involves the creation of Antibodies. – Clone of cells some plasma cells > Ab and others become memory cells – Long time to respond – Memory cells and Ag is presented again tha ...
Chapter 12 Test Review
Chapter 12 Test Review

... 29. Which process changes the mRNA base sequence into the amino acid sequence for protein synthesis? Translation. 30. When the codon “AUG” is read by a ribosome, it tells protein production to start. 31. How many amino acids are there? 20 32. When one or more bases from the DNA of a gene is lost, it ...
Chapter 12 Test Review
Chapter 12 Test Review

... 29. Which process changes the mRNA base sequence into the amino acid sequence for protein synthesis? Translation. 30. When the codon “AUG” is read by a ribosome, it tells protein production to start. 31. How many amino acids are there? 20 32. When one or more bases from the DNA of a gene is lost, it ...
Horak - Blumberg Lab
Horak - Blumberg Lab

... - Determine protein-DNA interaction...What do you need? - Protein of Interest= transcription factors → SBF (Swi4 subunit) → HA-Swi4 - DNA= transcription promoters → GAT2, HCM1, NDD1, PDR1, PLM2, POG1, SOK2, TOS4, ...
Cloning The Insulin Gene
Cloning The Insulin Gene

... to differ from human insulin by one amino acid; beef insulin by three. Although both work in humans to lower blood sugar, they are seen by the immune system as "foreign" and induce an antibody response in the patient that blunts their effect and requires higher doses. Two approaches have been tried ...
No Slide Title
No Slide Title

... Age-related changes in the immune system All lymphoid tissues decreases in mass and efficiency with age ...
Forensic DNA Analysis
Forensic DNA Analysis

... Single-cell sensitivity because each cell contains ~1000 mitochondria = very high contamination risk! Heteroplasmy - more than one mtDNA type manifesting in different tissues in the same individual Lower power of discrimination - maternal relatives all share the same mtDNA ...
Biology 303 EXAM III
Biology 303 EXAM III

... When referring to attenuation in regulation of the tryptophan operon it would be safe to say that when there are high levels of tryptophan available to the organism 1. the tryptophan operon is being transcribed at relatively high levels. 2. translational termination is likely. 3. transcriptional ter ...
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DNA vaccination



DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.
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