O A RIGINAL RTICLES
... disease with non-vaccine serotypes.25 Importantly, proteinbased immunisation strategies represent an attractive alternative, because they are likely to provide broader protection than the currently available conjugate vaccines. Pneumococcal protein vaccines may utilise individual proteins, or mixtur ...
... disease with non-vaccine serotypes.25 Importantly, proteinbased immunisation strategies represent an attractive alternative, because they are likely to provide broader protection than the currently available conjugate vaccines. Pneumococcal protein vaccines may utilise individual proteins, or mixtur ...
Painting the target around the matching profile
... When I spoke, I again presented the evidentiary profile shown in Fig. 2. This time, however, the profile labelled ‘Defendant’ was that of Dick rather than Tom. I suggested that the inclusion of Dick was rather problematic due to uncertainty about whether the 12 peak at locus D3 was a true allele and ...
... When I spoke, I again presented the evidentiary profile shown in Fig. 2. This time, however, the profile labelled ‘Defendant’ was that of Dick rather than Tom. I suggested that the inclusion of Dick was rather problematic due to uncertainty about whether the 12 peak at locus D3 was a true allele and ...
Exposure to natural pathogens reveals costly aphid
... exposure to Gram-positive bacterial elicitors and significantly decreased fecundity after exposure to fungal elicitors. However, unknown mechanisms may be at play as well, particularly given that insights gained into insect immune gene repertoires through genomics are revealing surprising deviations ...
... exposure to Gram-positive bacterial elicitors and significantly decreased fecundity after exposure to fungal elicitors. However, unknown mechanisms may be at play as well, particularly given that insights gained into insect immune gene repertoires through genomics are revealing surprising deviations ...
Systematic Mutational Analysis of the Yeast ACT1 Gene.
... additional mutation (actl-4; T. DUNN andD. SHORunpublished result). T w o of the three existing mutations lie at sites now known to be within a single subdomain of the folded protein (actl-1 changesa proline at residue 32 to leucine [or by convention, P32LI and actl-2 changes alanine at residue 58 t ...
... additional mutation (actl-4; T. DUNN andD. SHORunpublished result). T w o of the three existing mutations lie at sites now known to be within a single subdomain of the folded protein (actl-1 changesa proline at residue 32 to leucine [or by convention, P32LI and actl-2 changes alanine at residue 58 t ...
CHAPTER ONE: INTRODUCTION AND LITERATURE REVIEW 1.1
... donkeys (Reid et al. 1994), mules (Jackson 1936), horses (Otten et al. 1993), and two cases were reported from captive zebra in the United States of America (Löhr et al. 2005). Papillomaviruses are oncogenic viruses which infect epithelial cells causing hyperproliferative lesions. They infect cutane ...
... donkeys (Reid et al. 1994), mules (Jackson 1936), horses (Otten et al. 1993), and two cases were reported from captive zebra in the United States of America (Löhr et al. 2005). Papillomaviruses are oncogenic viruses which infect epithelial cells causing hyperproliferative lesions. They infect cutane ...
NIAID Biodefense Research Agenda for Category B and C Priority
... to focus on research related to the innate immune factors important for host protection against potential bioterrorist pathogens (see summary at http://www.niaid.nih.gov/ publications/pdf/biodimmunpan.pdf). The recommendations of these panels have provided valuable guidance in the development of new ...
... to focus on research related to the innate immune factors important for host protection against potential bioterrorist pathogens (see summary at http://www.niaid.nih.gov/ publications/pdf/biodimmunpan.pdf). The recommendations of these panels have provided valuable guidance in the development of new ...
HyperHEP B® S/D
... hepatitis B vaccine has been shown not to interfere with the active immune response to the vaccine (3). HyperHEP B® S/D is indicated for post-exposure prophylaxis in the following situations, unless it is known, by testing within the 24 previous months or can be established within 48 hours that the ...
... hepatitis B vaccine has been shown not to interfere with the active immune response to the vaccine (3). HyperHEP B® S/D is indicated for post-exposure prophylaxis in the following situations, unless it is known, by testing within the 24 previous months or can be established within 48 hours that the ...
Nerve activates contraction
... • The particular structure of a lymphocyte’s receptors is determined by genetic events that occur during its early development. • As an unspecialized cell differentiates into a B or T lymphocyte, segments of antibody genes or receptor genes are linked together by a type of genetic recombination, ge ...
... • The particular structure of a lymphocyte’s receptors is determined by genetic events that occur during its early development. • As an unspecialized cell differentiates into a B or T lymphocyte, segments of antibody genes or receptor genes are linked together by a type of genetic recombination, ge ...
Lampbrush Chromosomes of the Chicken
... more variable from animal to animal and even among similar sized oocytes from the same animal relative to the newt. The spread chromosome preparations were examined "live" with an inverted microscope and phase-contrast optics or, more routinely, as dry preparations before in situ hybridization or as ...
... more variable from animal to animal and even among similar sized oocytes from the same animal relative to the newt. The spread chromosome preparations were examined "live" with an inverted microscope and phase-contrast optics or, more routinely, as dry preparations before in situ hybridization or as ...
htp Pseudomonas aeruginosa AMANDA SWANEPOEL
... as those with cancer or AIDS and those suffering from cystic fibrosis and burns (Van Delden and Iglewski, 1998; Ramsey and Wozniak, 2005), but it has also been shown to infect plants and insects (Schroth et al., 1992; Rahme et al., 1995). The success of P. aeruginosa in colonizing these diverse envi ...
... as those with cancer or AIDS and those suffering from cystic fibrosis and burns (Van Delden and Iglewski, 1998; Ramsey and Wozniak, 2005), but it has also been shown to infect plants and insects (Schroth et al., 1992; Rahme et al., 1995). The success of P. aeruginosa in colonizing these diverse envi ...
Spring 2016 Biology Item Release Scoring Guide
... knowledge. Communicate with clarity, focus and organization using rich, investigative scenarios, real-world data and valid scientific information. ...
... knowledge. Communicate with clarity, focus and organization using rich, investigative scenarios, real-world data and valid scientific information. ...
Mucosal Immunity in Mycobacterial Infections Anna Tjärnlund
... through the modification of bacterial DNA, proteins and lipids (reviewed in Chan et al., 2001). NO can deaminate, as well as directly damage bacterial DNA, and has been demonstrated to induce apoptosis. RNIs also have the potential to disrupt signalling pathways, ...
... through the modification of bacterial DNA, proteins and lipids (reviewed in Chan et al., 2001). NO can deaminate, as well as directly damage bacterial DNA, and has been demonstrated to induce apoptosis. RNIs also have the potential to disrupt signalling pathways, ...
Chemical Genetics
... the details of a synthetic medium had not been worked out. (!Q that year W. J. Robbins demonstrated that Neurospora would grow on a medium containing inorganic salts, sugar and the vitamin, biotin ("minimal medium").) It therefore became possible to study the growth of Neurospora in a chemically def ...
... the details of a synthetic medium had not been worked out. (!Q that year W. J. Robbins demonstrated that Neurospora would grow on a medium containing inorganic salts, sugar and the vitamin, biotin ("minimal medium").) It therefore became possible to study the growth of Neurospora in a chemically def ...
Maintenance of DNA Methylation during the Arabidopsis Life Cycle
... methylation similar to FWA. DNA methylation could target putative CpG islands and transposons at the MEA locus (Xiao et al., 2003; Spillane et al., 2004). However, such elements are not essential for MEA imprinting, as suggested by conflicting genetic experiments, which casts doubt on the role of ME ...
... methylation similar to FWA. DNA methylation could target putative CpG islands and transposons at the MEA locus (Xiao et al., 2003; Spillane et al., 2004). However, such elements are not essential for MEA imprinting, as suggested by conflicting genetic experiments, which casts doubt on the role of ME ...
Two enhancer regions in the mouse En-2 locus
... CNS, En-2 is expressed in cells surrounding the developing pituitary (Davis et al., 1988, 1991). In addition, immunohistochemical analysis using a polyclonal antiserum (aEnhb-1) that detects both En-1 and En-2 protein has shown that one or both genes are expressed in presumptive myoblasts within the ...
... CNS, En-2 is expressed in cells surrounding the developing pituitary (Davis et al., 1988, 1991). In addition, immunohistochemical analysis using a polyclonal antiserum (aEnhb-1) that detects both En-1 and En-2 protein has shown that one or both genes are expressed in presumptive myoblasts within the ...
unit-2 genetics of prokaryotes and eukaryotic
... polyploid organism these could be easily produced and tolerable because more than two chromosome of same combination is present. Meiosis in monosomics behaves like haploids. In monosomics one of the chromosomes will go to only one pole during division and other pole will be devoid of it. Other chrom ...
... polyploid organism these could be easily produced and tolerable because more than two chromosome of same combination is present. Meiosis in monosomics behaves like haploids. In monosomics one of the chromosomes will go to only one pole during division and other pole will be devoid of it. Other chrom ...
The Development of a Genetic Marker for Resistance to Fescue
... hairs from which genomic DNA was later isolated were also collected at this time. Seventy two bulls enrolled in the 2007 University of Tennessee Bull Test located at the Spring Hill Research and Education Center was used. The bulls were assumed to have been grazing on endophyte-infected tall fescue. ...
... hairs from which genomic DNA was later isolated were also collected at this time. Seventy two bulls enrolled in the 2007 University of Tennessee Bull Test located at the Spring Hill Research and Education Center was used. The bulls were assumed to have been grazing on endophyte-infected tall fescue. ...
Free Sample
... c. Extrachromosomal genetic element that can carry a recombinant DNA molecule into a host bacterial cell d. Substance that can carry an electric current in solution ____ 36. Which of the following must be true when using the Hardy-Weinberg equation? a. The population must be large c. Mating must occ ...
... c. Extrachromosomal genetic element that can carry a recombinant DNA molecule into a host bacterial cell d. Substance that can carry an electric current in solution ____ 36. Which of the following must be true when using the Hardy-Weinberg equation? a. The population must be large c. Mating must occ ...
The Arabidopsis RAD51 paralogs RAD51B, RAD51D and XRCC2
... of DNA damage, double-strand DNA breaks (DSBs) are caused by ionizing radiation, genotoxic chemicals or errors in DNA replication (Kuzminov, 2001; Tonami et al., 2005). Failure to correctly repair DSBs can cause genome instability, mutations, cell cycle arrest and even cell death (Glazer & Glazunov, ...
... of DNA damage, double-strand DNA breaks (DSBs) are caused by ionizing radiation, genotoxic chemicals or errors in DNA replication (Kuzminov, 2001; Tonami et al., 2005). Failure to correctly repair DSBs can cause genome instability, mutations, cell cycle arrest and even cell death (Glazer & Glazunov, ...
Novel technologies and emerging biomarkers for personalized
... Moreover, melanoma patients seropositive for the cancertestis antigen NY-ESO-1 were more likely to experience clinical benefit than those who were seronegative [57]. In contrast, there was no significant association between humoral response to tumor antigens and clinical benefit in two other studies ...
... Moreover, melanoma patients seropositive for the cancertestis antigen NY-ESO-1 were more likely to experience clinical benefit than those who were seronegative [57]. In contrast, there was no significant association between humoral response to tumor antigens and clinical benefit in two other studies ...
Natural Antimicrobial Peptides: Pleiotropic Molecules in Host Defense
... parasites, bacteria and viruses. But it is the innate immunity that is responsible for the rapid initial defense against the pathogen. The co-evolution of hosts and pathogens has led to a diverse group of peptides that the host produces in order to kill or reduce the infective microbes. These peptid ...
... parasites, bacteria and viruses. But it is the innate immunity that is responsible for the rapid initial defense against the pathogen. The co-evolution of hosts and pathogens has led to a diverse group of peptides that the host produces in order to kill or reduce the infective microbes. These peptid ...
Analysis of Drosophila Species Genome Size and Satellite DNA
... elements typical of heterochromatin, may have repeatspecific shrinkage mechanisms, such as unequal meiotic exchange between sister chromatids or replication errors (Britten and Kohne 1968; Southern 1975; Smith 1976; Stephan and Cho 1994; Petrov 2001). Understanding the levels and distributions of he ...
... elements typical of heterochromatin, may have repeatspecific shrinkage mechanisms, such as unequal meiotic exchange between sister chromatids or replication errors (Britten and Kohne 1968; Southern 1975; Smith 1976; Stephan and Cho 1994; Petrov 2001). Understanding the levels and distributions of he ...
DNA vaccination
DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.