Doctoral thesis from the Department of Immunology, the Wenner-Gren
... between CD4+ T cells and B cells in the secondary lymphoid tissues [6]. T-B cell interaction results in B cell activation via ligation of co-stimulatory molecules expressed on surfaces of activated T cells, such as CD40L and cytokines produced by them [7, 8]. Subsequent to this interaction, naïve B ...
... between CD4+ T cells and B cells in the secondary lymphoid tissues [6]. T-B cell interaction results in B cell activation via ligation of co-stimulatory molecules expressed on surfaces of activated T cells, such as CD40L and cytokines produced by them [7, 8]. Subsequent to this interaction, naïve B ...
Demarcation of coding and non-coding regions of DNA using linear
... number of possible combinations are 4 3 = 64. Thus there are 64 different codons possible. These codons give rise to amino acid, which in turn produce proteins. There are totally 20 different amino acids. This gives an implicit meaning that the mapping between codons and the amino acids is a many to ...
... number of possible combinations are 4 3 = 64. Thus there are 64 different codons possible. These codons give rise to amino acid, which in turn produce proteins. There are totally 20 different amino acids. This gives an implicit meaning that the mapping between codons and the amino acids is a many to ...
2- pcr primer design and reaction optimisation
... The optimum length of a primer depends upon its (A+T) content, and the Tm of its partner if one runs the risk of having problems such as described above. Apart from the Tm, a prime consideration is that the primers should be complex enough so that the likelihood of annealing to sequences other than ...
... The optimum length of a primer depends upon its (A+T) content, and the Tm of its partner if one runs the risk of having problems such as described above. Apart from the Tm, a prime consideration is that the primers should be complex enough so that the likelihood of annealing to sequences other than ...
Immunological studies on Swine Influenza Virus in Massimiliano Baratelli
... prophylaxis; in particular they are based on vaccines eliciting humoral response. Escaping capacity and high variability of SwIV make that the efficacy of those can be compromised; thus vaccines need to be periodically updated. This problem is shared in human health and thus rationally designed vacc ...
... prophylaxis; in particular they are based on vaccines eliciting humoral response. Escaping capacity and high variability of SwIV make that the efficacy of those can be compromised; thus vaccines need to be periodically updated. This problem is shared in human health and thus rationally designed vacc ...
Myths and concerns about vaccination
... There has been concern about the morality of receiving vaccines when the cells in which the vaccine virus is grown may have been originally obtained from an aborted fetus. Although bacteria can, under the right supportive conditions, survive and replicate on their own, viruses require cells in order ...
... There has been concern about the morality of receiving vaccines when the cells in which the vaccine virus is grown may have been originally obtained from an aborted fetus. Although bacteria can, under the right supportive conditions, survive and replicate on their own, viruses require cells in order ...
Maggini S et al. Selected vitamins and trace elements support
... alterations could contribute to degenerative disorders such as cancer and cardiovascular disease7,48,49. The immune-enhancing role of vitamin C has recently been reviewed50. Vitamin C is highly concentrated in leukocytes and is used rapidly during infection. In fact, it has been defined as a stimula ...
... alterations could contribute to degenerative disorders such as cancer and cardiovascular disease7,48,49. The immune-enhancing role of vitamin C has recently been reviewed50. Vitamin C is highly concentrated in leukocytes and is used rapidly during infection. In fact, it has been defined as a stimula ...
ABSTRACT
... their surroundings which initiates several different pathways. They can directly destroy microbes, or present antigen to alert the adaptive immune system. First, however, these cells must be able to distinguish self from non-self. The innate im- ...
... their surroundings which initiates several different pathways. They can directly destroy microbes, or present antigen to alert the adaptive immune system. First, however, these cells must be able to distinguish self from non-self. The innate im- ...
reactive_oxygen_species
... The loss of Nrf2 causes a decrease in GST expression and increased levels of ROS. This ultimately leads to DNA damage associated with tumorigenesis. ...
... The loss of Nrf2 causes a decrease in GST expression and increased levels of ROS. This ultimately leads to DNA damage associated with tumorigenesis. ...
Bioassay-Validated Recombinant Cytokines
... B cell factor (EBF), which in turn, regulates expression of B cell-specific genes required for the transition from lymphoid progenitor to pro-B cells. IL-7 also plays a role in the development of secondary lymphoid tissues. IL-7 is necessary to specify CD8 lineage differentiation during CD4/CD8 cell ...
... B cell factor (EBF), which in turn, regulates expression of B cell-specific genes required for the transition from lymphoid progenitor to pro-B cells. IL-7 also plays a role in the development of secondary lymphoid tissues. IL-7 is necessary to specify CD8 lineage differentiation during CD4/CD8 cell ...
Candida
... alarmins produced by vaginal epithelial cells in response to Candida. Based on the putative role for the Th17 response in mucosal candidiasis as well as S100 alarmin induction, this study aimed to determine whether the Th17 pathway plays a role in the S100 alarmin-mediated acute inflammation during ...
... alarmins produced by vaginal epithelial cells in response to Candida. Based on the putative role for the Th17 response in mucosal candidiasis as well as S100 alarmin induction, this study aimed to determine whether the Th17 pathway plays a role in the S100 alarmin-mediated acute inflammation during ...
Lung inflammatory responses
... adhesion, chemotaxis, and activation of leukocyte populations. While some chemokines are constitutively expressed, others are either up or downregulated in association with inflammation. Those chemokines active in inflammation are typically produced in response to infection by pathogenic microbes or ...
... adhesion, chemotaxis, and activation of leukocyte populations. While some chemokines are constitutively expressed, others are either up or downregulated in association with inflammation. Those chemokines active in inflammation are typically produced in response to infection by pathogenic microbes or ...
Here - Vanderbilt University
... can be transmitted to a subsequent host while the initial host is alive or after its death. The time between colonization and transmission can be very short; some of these infectious agents are highly pathogenic and are lethal within hours of infection.18 For that reason, bacterial and fungal pathog ...
... can be transmitted to a subsequent host while the initial host is alive or after its death. The time between colonization and transmission can be very short; some of these infectious agents are highly pathogenic and are lethal within hours of infection.18 For that reason, bacterial and fungal pathog ...
- Journal of Clinical Investigation
... a potential role for viral infections in the progression and/or exacerbation of lung fibrosis (10, 11). Viruses and other intracellular pathogens can cause apoptosis of alveolar epithelial cells, which is implicated in the pathogenesis of lung fibrosis (12). However, at present, it is unclear to wha ...
... a potential role for viral infections in the progression and/or exacerbation of lung fibrosis (10, 11). Viruses and other intracellular pathogens can cause apoptosis of alveolar epithelial cells, which is implicated in the pathogenesis of lung fibrosis (12). However, at present, it is unclear to wha ...
Really Essential Medical Immunology Arthur Rabson
... such as ciliary movement, coughing and sneezing. Among other mechanical factors that help protect the epithelial surfaces, one should also include the washing action of tears, saliva and urine. Many of the secreted body fluids contain bactericidal components, such as acid in gastric juice, spermine ...
... such as ciliary movement, coughing and sneezing. Among other mechanical factors that help protect the epithelial surfaces, one should also include the washing action of tears, saliva and urine. Many of the secreted body fluids contain bactericidal components, such as acid in gastric juice, spermine ...
Pathways Molecule-Dependent and
... Japanese encephalitis virus (JEV), which is a mosquito-borne member of the genus Flavivirus, such as West Nile and dengue viruses, is responsible for most acute and epidemic cases of viral encephalitis (22, 23). Approximately 60% of the world population inhabits JEV endemic areas, and the virus is c ...
... Japanese encephalitis virus (JEV), which is a mosquito-borne member of the genus Flavivirus, such as West Nile and dengue viruses, is responsible for most acute and epidemic cases of viral encephalitis (22, 23). Approximately 60% of the world population inhabits JEV endemic areas, and the virus is c ...
Programação detalhada
... are focused primarily on the immunoregulatory properties of trophoblast cells, which are the first cells to differentiate from the embryo, and ultimately form the fetal component of the placenta. Trophoblast cells are the only cells derived from the blastocyst that are in direct contact with materna ...
... are focused primarily on the immunoregulatory properties of trophoblast cells, which are the first cells to differentiate from the embryo, and ultimately form the fetal component of the placenta. Trophoblast cells are the only cells derived from the blastocyst that are in direct contact with materna ...
Common measures of immune function vary with time of day and
... with handling stress (Buehler et al., 2008). This issue is compounded by the fact that field-collected blood samples are typically obtained opportunistically over the course of the day as individuals are captured, and that some amount of time elapses between capture of an individual and taking of a ...
... with handling stress (Buehler et al., 2008). This issue is compounded by the fact that field-collected blood samples are typically obtained opportunistically over the course of the day as individuals are captured, and that some amount of time elapses between capture of an individual and taking of a ...
PDF
... (MCMV). pDCs are the major source of type I IFN (IFN-I) during MCMV infection. This response requires pDC-intrinsic MyD88-dependent signaling by Toll-Like Receptors 7 and 9. Provided that they express appropriate recognition receptors such as Ly49H, NK cells can directly sense and kill MCMV-infected ...
... (MCMV). pDCs are the major source of type I IFN (IFN-I) during MCMV infection. This response requires pDC-intrinsic MyD88-dependent signaling by Toll-Like Receptors 7 and 9. Provided that they express appropriate recognition receptors such as Ly49H, NK cells can directly sense and kill MCMV-infected ...
Ab Initio Modeling of Biological Systems - Psi-k
... However, there are many areas in which the use of effective potentials may be not appropriate, and more sophisticated and accurate approaches are required. An alternative is offered by ab initio molecular dynamics (AIMD). AIMD in the Born-Oppheneimer approximation can be efficiently performed using ...
... However, there are many areas in which the use of effective potentials may be not appropriate, and more sophisticated and accurate approaches are required. An alternative is offered by ab initio molecular dynamics (AIMD). AIMD in the Born-Oppheneimer approximation can be efficiently performed using ...
Lung inflammatory responses
... adhesion, chemotaxis, and activation of leukocyte populations. While some chemokines are constitutively expressed, others are either up or downregulated in association with inflammation. Those chemokines active in inflammation are typically produced in response to infection by pathogenic microbes or ...
... adhesion, chemotaxis, and activation of leukocyte populations. While some chemokines are constitutively expressed, others are either up or downregulated in association with inflammation. Those chemokines active in inflammation are typically produced in response to infection by pathogenic microbes or ...
Bivalve immunity and response to infections: Are we
... The temporarily dynamic nature of bivalve immune responses to infections has been highlighted in a large number of studies [reviewed by [4]]. This has often been shown or suggested to be linked to change in disease stage status over time or to the mobilization of immune effectors towards infection f ...
... The temporarily dynamic nature of bivalve immune responses to infections has been highlighted in a large number of studies [reviewed by [4]]. This has often been shown or suggested to be linked to change in disease stage status over time or to the mobilization of immune effectors towards infection f ...
Cutaneous Lymphoma at Injection Sites
... FeLV vaccination was administered to 5 of 17 cats. No rabies vaccines were administered, since Italy is a country free of rabies. Exact time span between vaccination and development of lymphoma was available for 5 of 17 cats: lesions developed 15 days after last FeLV vaccination in cats Nos. 3 and 6 ...
... FeLV vaccination was administered to 5 of 17 cats. No rabies vaccines were administered, since Italy is a country free of rabies. Exact time span between vaccination and development of lymphoma was available for 5 of 17 cats: lesions developed 15 days after last FeLV vaccination in cats Nos. 3 and 6 ...
DNA vaccination
DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.