Strains to Theiler`s Virus Persistent Infection the Difference of
... accompanied by chronic inflammation and primary demyelination. This late disease is studied as a model for multiple sclerosis (1, 2). Genetically resistant strains of mice clear the infection after the first 2 wk following inoculation and do not present with demyelination. Resistance/susceptibility ...
... accompanied by chronic inflammation and primary demyelination. This late disease is studied as a model for multiple sclerosis (1, 2). Genetically resistant strains of mice clear the infection after the first 2 wk following inoculation and do not present with demyelination. Resistance/susceptibility ...
Initiation and Regulation of Type 2 Immunity and Inflammation at
... Identifying the cellular and molecular requirements for initiating and regulating type 2 immunity and inflammation is essential for the development of new vaccines against helminth parasites and treatments for atopic diseases. CD11c+ dendritic cells (DCs) are critical antigen-presenting cells (APCs) ...
... Identifying the cellular and molecular requirements for initiating and regulating type 2 immunity and inflammation is essential for the development of new vaccines against helminth parasites and treatments for atopic diseases. CD11c+ dendritic cells (DCs) are critical antigen-presenting cells (APCs) ...
Full text - The American Association of Immunologists
... for their pioneering studies on the major histocompatibility complex (MHC). Benacerraf demonstrated that genetic factors regulate an individual’s immune responses. This discovery shed light on the association of certain autoimmune diseases with particular MHC antigens and the variations in individua ...
... for their pioneering studies on the major histocompatibility complex (MHC). Benacerraf demonstrated that genetic factors regulate an individual’s immune responses. This discovery shed light on the association of certain autoimmune diseases with particular MHC antigens and the variations in individua ...
Update on herpes zoster vaccination
... Sources of information Published results of clinical trials and other studies, recommendations from the Canadian National Advisory Committee on Immunization, and the US Advisory Committee on Immunization Practices; data were also obtained from the vaccine’s Health Canada–approved product monograph. ...
... Sources of information Published results of clinical trials and other studies, recommendations from the Canadian National Advisory Committee on Immunization, and the US Advisory Committee on Immunization Practices; data were also obtained from the vaccine’s Health Canada–approved product monograph. ...
4 results 28.06.13
... The crude ethanolic extract and its four fractions [hexane (F1), chloroform (F2), n-butanol (F3) and aqueous (F4)] prepared from the twigs of AS were assessed in BALB/c mice for their immunomodulatory activities after administering at 3.0, 10 and 30 mg/kg doses. The observations made on these test s ...
... The crude ethanolic extract and its four fractions [hexane (F1), chloroform (F2), n-butanol (F3) and aqueous (F4)] prepared from the twigs of AS were assessed in BALB/c mice for their immunomodulatory activities after administering at 3.0, 10 and 30 mg/kg doses. The observations made on these test s ...
The Cytokeratin Filament-Aggregating Protein Filaggrin Is the Target
... Volume 92, September 1993, 1387-1393 ...
... Volume 92, September 1993, 1387-1393 ...
Meningococcal vaccines for Australians
... multicomponent vaccine designed to provide protection against MenB. It was registered in Australia in August 2013. It contains four major antigens that are highly conserved across multiple MenB strains. Based on laboratory tests, it is estimated that the vaccine induces protective antibodies against ...
... multicomponent vaccine designed to provide protection against MenB. It was registered in Australia in August 2013. It contains four major antigens that are highly conserved across multiple MenB strains. Based on laboratory tests, it is estimated that the vaccine induces protective antibodies against ...
Immunology of Viral Disease, How to Curb Persistent Infection Simone C. Zimmerli
... Hence the existence of Ag-specific CD8 cells secreting both IFN-γ and IL-2 should be beneficial for controlling infection. In this first work we determined the percentage of IFN-γ/IL-2 double positive and single IFN-γ secreting CD8 T cells against antigens HIV-1, CMV, EBV and Flu in three groups of ...
... Hence the existence of Ag-specific CD8 cells secreting both IFN-γ and IL-2 should be beneficial for controlling infection. In this first work we determined the percentage of IFN-γ/IL-2 double positive and single IFN-γ secreting CD8 T cells against antigens HIV-1, CMV, EBV and Flu in three groups of ...
CC Chemokine Receptor 4 Contributes to Innate NK and Chronic
... cells, but mounting evidence suggests that this is not the case. The CCR4 genetic deletion had no effect in a mouse model of Th2-dependent ovalbumin (OVA)–elicited allergy airway response.2 We demonstrated that CCR4! Th1 and Th2 cells were detected in mouse models of Th1 and Th2 cell-mediated pulmon ...
... cells, but mounting evidence suggests that this is not the case. The CCR4 genetic deletion had no effect in a mouse model of Th2-dependent ovalbumin (OVA)–elicited allergy airway response.2 We demonstrated that CCR4! Th1 and Th2 cells were detected in mouse models of Th1 and Th2 cell-mediated pulmon ...
C YTOKINES AND IMMUNE BALANCE IN PREECLAMPSIA
... adaptive immune response takes effect, and during this time the innate immune response has a critical role in controlling infections (Janeway 2005). Activated macrophages and NK cells secrete cytokines and chemokines, which initiate the inflammatory response and aid the destruction of phagocytosed p ...
... adaptive immune response takes effect, and during this time the innate immune response has a critical role in controlling infections (Janeway 2005). Activated macrophages and NK cells secrete cytokines and chemokines, which initiate the inflammatory response and aid the destruction of phagocytosed p ...
Airway Inflammation and Bronchial Remodelling in - (BORA)
... mucosa of TDI asthmatics [15]. However, some authors observed Th1-like response characterized by an increase in the number of neutrophils and the levels of IFN-c and IL-8 [16–18]. Because the cellular mechanisms responsible for diisocyanate-induced asthma and the determinants of exposure are not ful ...
... mucosa of TDI asthmatics [15]. However, some authors observed Th1-like response characterized by an increase in the number of neutrophils and the levels of IFN-c and IL-8 [16–18]. Because the cellular mechanisms responsible for diisocyanate-induced asthma and the determinants of exposure are not ful ...
File - Respiratory Therapy Files
... How it works: It relaxes airway muscles by impacting neurotransmitters sent to the autonomic nervous system, a process different than how beta-agonist drugs act. Sometimes given in addition to shorter-acting bronchodilator therapy, if the shorteracting meds are not doing enough. Tends to have longer ...
... How it works: It relaxes airway muscles by impacting neurotransmitters sent to the autonomic nervous system, a process different than how beta-agonist drugs act. Sometimes given in addition to shorter-acting bronchodilator therapy, if the shorteracting meds are not doing enough. Tends to have longer ...
Chapter 29 Slides
... by transfection - injection of plasmid DNA into recipient cells • Plasmids can be injected into fertilized eggs in mice • Expression is usually variable, because the gene is inserted randomly • Growth hormone transfection produces mice that are very large! ...
... by transfection - injection of plasmid DNA into recipient cells • Plasmids can be injected into fertilized eggs in mice • Expression is usually variable, because the gene is inserted randomly • Growth hormone transfection produces mice that are very large! ...
Harvey ras (H-ras) Point Mutations Are Induced by 4
... DMBA, and the promoter, TPA (12, 13). Continuous exposure of squamous cells to DMBA and TPA induced H-ras mutations on chromosome 7 in greater than 90% of mice (14). H-ras appeared to be activated by specific mutations which can be affected by the initiating carcinogen (15). Since tumors do not deve ...
... DMBA, and the promoter, TPA (12, 13). Continuous exposure of squamous cells to DMBA and TPA induced H-ras mutations on chromosome 7 in greater than 90% of mice (14). H-ras appeared to be activated by specific mutations which can be affected by the initiating carcinogen (15). Since tumors do not deve ...
Plant-Microbe Interaction
... discrimination theory of immune responses is incomplete. For plants, research efforts nowadays still focus on the detection of the non-self (i.e., HAMPs and PAMPs), although early studies used terms such as “wounding,” “wound response,” or “wound hormone” to denominate defensive responses to herbivo ...
... discrimination theory of immune responses is incomplete. For plants, research efforts nowadays still focus on the detection of the non-self (i.e., HAMPs and PAMPs), although early studies used terms such as “wounding,” “wound response,” or “wound hormone” to denominate defensive responses to herbivo ...
Repression by RAZ of Epstein-Barr virus bZIP transcription factor
... EB1 protein present in the transfected cells whereas 20 I11of the same extract was used to visualize the FLAG-RAZ protein. Since using different antibodies to compare the amounts of EB1 and RAZ is not state of the art, we had to show that at the dilution used, antibodies mAbM2 and mAbZ125 detect EBI ...
... EB1 protein present in the transfected cells whereas 20 I11of the same extract was used to visualize the FLAG-RAZ protein. Since using different antibodies to compare the amounts of EB1 and RAZ is not state of the art, we had to show that at the dilution used, antibodies mAbM2 and mAbZ125 detect EBI ...
KAIE LOKK Comparative genome-wide DNA methylation
... The human genome contains about 29 million CpG dinucleotides where a cytosine base is followed by a guanine base. Cytosine in the CpG dinucleotide can exist in either a methylated or unmethylated state. DNA methyltransferase (DNMT) enzymes can add a methyl group to cytosine to form 5-methylcytosine ...
... The human genome contains about 29 million CpG dinucleotides where a cytosine base is followed by a guanine base. Cytosine in the CpG dinucleotide can exist in either a methylated or unmethylated state. DNA methyltransferase (DNMT) enzymes can add a methyl group to cytosine to form 5-methylcytosine ...
Cloning and expression analysis of three novel CC chemokine
... 2.1 Cloning of Japanese flounder CC chemokine genes .................................... 6 2.2 Expression analysis of three novel CC chemokine genes in healthy fish .......... 6 2.3 Gene expression of three novel CC chemokines after pathogens infection ....... 7 ...
... 2.1 Cloning of Japanese flounder CC chemokine genes .................................... 6 2.2 Expression analysis of three novel CC chemokine genes in healthy fish .......... 6 2.3 Gene expression of three novel CC chemokines after pathogens infection ....... 7 ...
Immune components of bovine colostrum and milk
... only kill bacteria directly through phagocytosis, but are also responsible for the production of many cytokines, reactive oxygen species, and antimicrobial peptides. Several recent reports surveying the minor constituents of milk from healthy and infected glands have noted the predominance of host d ...
... only kill bacteria directly through phagocytosis, but are also responsible for the production of many cytokines, reactive oxygen species, and antimicrobial peptides. Several recent reports surveying the minor constituents of milk from healthy and infected glands have noted the predominance of host d ...
Altitude, exercise and immune function
... There have been numerous studies documenting the effect of a single bout of exercise on immune function (19,21,27). Generally, depending upon the exercise intensity, duration and training status of the individual, exercise has been shown to be a physical stressor that can transiently affect immune f ...
... There have been numerous studies documenting the effect of a single bout of exercise on immune function (19,21,27). Generally, depending upon the exercise intensity, duration and training status of the individual, exercise has been shown to be a physical stressor that can transiently affect immune f ...
Stage-specific expressions of four different ribonuclease H genes in
... patients (Desjeux, 1994; Alexander et al. 1999). Amastigotes multiply in the macrophages and eventually lyse them. Leishmania and other related protozoa of the genus Trypanosoma (T. brucei and T. cruzi) are considered as primitive eukaryotes. Fortunately, although these early eukaryotes have many si ...
... patients (Desjeux, 1994; Alexander et al. 1999). Amastigotes multiply in the macrophages and eventually lyse them. Leishmania and other related protozoa of the genus Trypanosoma (T. brucei and T. cruzi) are considered as primitive eukaryotes. Fortunately, although these early eukaryotes have many si ...
DNA vaccination
DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.