Real time PCR and it`s role in diagnosis
... peptides The epithelium lining the airways is the first tissue to encounter pathogens and their products; it is therefore, critical to the innate immune system and is the front line of the host defence against invading microorganisms. Some peptides which are classified in an antimicrobial group , ca ...
... peptides The epithelium lining the airways is the first tissue to encounter pathogens and their products; it is therefore, critical to the innate immune system and is the front line of the host defence against invading microorganisms. Some peptides which are classified in an antimicrobial group , ca ...
History of Discoveries in Molecular Biology
... like a Honey-comb, but that the pores of it were not regular. . . . these pores, or cells, . . . were indeed the first microscopical pores I ever saw, and perhaps, that were ever seen, for I had not met with any Writer or Person, that had made any mention of them before this. . . BTC 563 ...
... like a Honey-comb, but that the pores of it were not regular. . . . these pores, or cells, . . . were indeed the first microscopical pores I ever saw, and perhaps, that were ever seen, for I had not met with any Writer or Person, that had made any mention of them before this. . . BTC 563 ...
GENtle, a free multi-purpose molecular biology tool
... A result of modern techniques in molecular biology, especially DNA sequencing, is the exponentially growing amount of available data. Besides giant, specialized databases, which are accessible over the Internet, all work groups in the field of molecular biology today need to handle, modify, analyze ...
... A result of modern techniques in molecular biology, especially DNA sequencing, is the exponentially growing amount of available data. Besides giant, specialized databases, which are accessible over the Internet, all work groups in the field of molecular biology today need to handle, modify, analyze ...
press kit - Sanofi Pasteur
... in endemic countries. In December 2015, Sanofi Pasteur’s dengue vaccine was approved in Mexico, making it the first vaccine to be licensed in the world for active immunization against dengue disease in preadolescents, adolescents and adults (9 to 45 years of age) living in endemic areas. This is a h ...
... in endemic countries. In December 2015, Sanofi Pasteur’s dengue vaccine was approved in Mexico, making it the first vaccine to be licensed in the world for active immunization against dengue disease in preadolescents, adolescents and adults (9 to 45 years of age) living in endemic areas. This is a h ...
Integr. Comp. Biol.-2011-Rollins-Smith-552
... them. Individual purified antimicrobial peptides inhibit growth of B. dendrobatidis in vitro (reviewed by Rollins-Smith and Conlon 2005; Rollins-Smith 2009), and some inhibit growth of another fungus, Basidiobolus ranarum (Rollins-Smith et al. 2002a). Two of the peptides from Xenopus laevis act syne ...
... them. Individual purified antimicrobial peptides inhibit growth of B. dendrobatidis in vitro (reviewed by Rollins-Smith and Conlon 2005; Rollins-Smith 2009), and some inhibit growth of another fungus, Basidiobolus ranarum (Rollins-Smith et al. 2002a). Two of the peptides from Xenopus laevis act syne ...
ABSTRACT Title of Document:
... using three different antigen systems – anti-BCR antibody –based antigens, phosphorylcholine (PC)-based antigens, and hen egg lysozyme (HEL)-based antigens. While both paucivalent and polyvalent antigens induced the redistribution of surface BCR into microdomains, polyvalent antigen-induced BCR micr ...
... using three different antigen systems – anti-BCR antibody –based antigens, phosphorylcholine (PC)-based antigens, and hen egg lysozyme (HEL)-based antigens. While both paucivalent and polyvalent antigens induced the redistribution of surface BCR into microdomains, polyvalent antigen-induced BCR micr ...
Polysaccharide-protein conjugate vaccines
... induction folloWing immunization by these antigens. [0004] T-independent polysaccharide antigens can be con verted to T-dependent antigens by covalent attachment of the polysaccharides to protein molecules. B cells that bind the polysaccharide component of the conjugate vaccine can be activated by h ...
... induction folloWing immunization by these antigens. [0004] T-independent polysaccharide antigens can be con verted to T-dependent antigens by covalent attachment of the polysaccharides to protein molecules. B cells that bind the polysaccharide component of the conjugate vaccine can be activated by h ...
Cell-free eukaryotic systems for the production
... overhangs, which introduced overhang sequences that were complementary for the primers used in PCR step two. In the second PCR step, adapter primers were used, which introduced the regulatory sequences needed for transcription and translation such as a T7 promotor sequence and a ribosome-binding sit ...
... overhangs, which introduced overhang sequences that were complementary for the primers used in PCR step two. In the second PCR step, adapter primers were used, which introduced the regulatory sequences needed for transcription and translation such as a T7 promotor sequence and a ribosome-binding sit ...
study of the human humoral immune response against rotavirus
... A better understanding of the frequencies of antigen-specific mBc subsets and their association with serological memory –defined as the persistence of Abs levels in the absence of the antigen [30]– is also important to identify valuable correlates of protection for vaccines [31, 32]. The mechanisms ...
... A better understanding of the frequencies of antigen-specific mBc subsets and their association with serological memory –defined as the persistence of Abs levels in the absence of the antigen [30]– is also important to identify valuable correlates of protection for vaccines [31, 32]. The mechanisms ...
Herpes simplex virus and varicella zoster virus, Open Access
... the ability to study the viruses outside the human host. First, HSV-1 is robust for growth in tissue culture, while VZV is highly cell-associated, and cannot be obtained in titers needed to carry out synchronous VZV infections. Second, VZV is much more host restricted than HSV-1. There are numerous ...
... the ability to study the viruses outside the human host. First, HSV-1 is robust for growth in tissue culture, while VZV is highly cell-associated, and cannot be obtained in titers needed to carry out synchronous VZV infections. Second, VZV is much more host restricted than HSV-1. There are numerous ...
Immune function across generations: integrating mechanism and
... offspring in terms of antibody transmission, then the maternal effect is described as an indirect genetic effect (IGE) (Wolf et al. 1998). Depending on the dynamics of the system, IGEs may hasten or retard the evolutionary response to selection, reverse the direction of a response or create oscillat ...
... offspring in terms of antibody transmission, then the maternal effect is described as an indirect genetic effect (IGE) (Wolf et al. 1998). Depending on the dynamics of the system, IGEs may hasten or retard the evolutionary response to selection, reverse the direction of a response or create oscillat ...
the cd40 receptor - Immunotechnology
... tissues that acts in concert to protect us against different pathogens. It is composed of the evolutionary ancient innate compartment and the more complex adaptive compartment, where the latter is restricted to vertebrates. Together with the nerve system, the immune system is the major adaptive syst ...
... tissues that acts in concert to protect us against different pathogens. It is composed of the evolutionary ancient innate compartment and the more complex adaptive compartment, where the latter is restricted to vertebrates. Together with the nerve system, the immune system is the major adaptive syst ...
NOD2 Variants and Antibody Response to Microbial Antigens in
... ligands such as CBir1 flagellin, flagellin X, lipoteichoic acid, muramyl dipeptide (MDP), and CpG oligodeoxynucleotides and a compensatory increase in adaptive CD4 T-cell response to CBir1 flagellin and flagellin X.31 In human studies, several genes or loci have thus far been described that may be a ...
... ligands such as CBir1 flagellin, flagellin X, lipoteichoic acid, muramyl dipeptide (MDP), and CpG oligodeoxynucleotides and a compensatory increase in adaptive CD4 T-cell response to CBir1 flagellin and flagellin X.31 In human studies, several genes or loci have thus far been described that may be a ...
The Rad50 Signature Motif: Essential to ATP Binding and
... The Mre11 protein contains a nuclease domain that is highly conserved and related to the lambda phosphatase family of phosphoesterases. The crystal structure of an Mre11 homolog from Pyrococcus furiosus shows five conserved motifs within the N-terminal half of Mre11 that coordinate two manganese ion ...
... The Mre11 protein contains a nuclease domain that is highly conserved and related to the lambda phosphatase family of phosphoesterases. The crystal structure of an Mre11 homolog from Pyrococcus furiosus shows five conserved motifs within the N-terminal half of Mre11 that coordinate two manganese ion ...
Plant Functional Genomics Plant Functional Genomics
... and E. coli as the host, making library construction and subsequent downstream procedures efficient and easy to perform. Recombinant DNA inserts up to 200 kb can be efficiently cloned and stably maintained in E. coli. Although the insert size cloning capacity is much lower than that of the YAC syste ...
... and E. coli as the host, making library construction and subsequent downstream procedures efficient and easy to perform. Recombinant DNA inserts up to 200 kb can be efficiently cloned and stably maintained in E. coli. Although the insert size cloning capacity is much lower than that of the YAC syste ...
chapter 1
... and high annual healthcare costs.8-11 The background of the development of allergic diseases is suggested to be multifactorial in which both genetic and environmental factors play a role.12 Preterm birth might also play a role in the development of allergic disease, however conflicting results have ...
... and high annual healthcare costs.8-11 The background of the development of allergic diseases is suggested to be multifactorial in which both genetic and environmental factors play a role.12 Preterm birth might also play a role in the development of allergic disease, however conflicting results have ...
Getting Started With Gel Electrophoresis
... We carry two varieties of electrophoresis power supplies: those that can run two simultaneous gels and those that can run four simultaneous gels. Each can be adjusted from 10 to 300V and has a built-in safety switch to limit the maximum current. ...
... We carry two varieties of electrophoresis power supplies: those that can run two simultaneous gels and those that can run four simultaneous gels. Each can be adjusted from 10 to 300V and has a built-in safety switch to limit the maximum current. ...
Gene Section USP1 (ubiquitin specific peptidase 1) Atlas of Genetics and Cytogenetics
... et al., 1998). USP1 belongs to the ubiquitin specific protease (USP) family of human deubiquitinases (DUBs). Like other members of its family, it harbours a highly conserved USP domain organization comprising a N-terminal Cys box and a C-terminal His box, which contain the catalytic residues (C90, H ...
... et al., 1998). USP1 belongs to the ubiquitin specific protease (USP) family of human deubiquitinases (DUBs). Like other members of its family, it harbours a highly conserved USP domain organization comprising a N-terminal Cys box and a C-terminal His box, which contain the catalytic residues (C90, H ...
Establishment of immunohistochemical double staining
... called nivolumab and pembrolizumab have been approved for clinical trials by the FDA in the United States for treatment against these cancer forms since the response in patients is good and the extended ...
... called nivolumab and pembrolizumab have been approved for clinical trials by the FDA in the United States for treatment against these cancer forms since the response in patients is good and the extended ...
Plant Molecular Biology
... All plant seeds were sterilized by subsequent soakings in concentrated sulfuric acid and bleach as described by Van Brussel et al. [23]. After germination, seedlings with a tooth length of about 1 cm were transferred to test tubes containing Jensen agar slants [23]. After incubation of the seedlings ...
... All plant seeds were sterilized by subsequent soakings in concentrated sulfuric acid and bleach as described by Van Brussel et al. [23]. After germination, seedlings with a tooth length of about 1 cm were transferred to test tubes containing Jensen agar slants [23]. After incubation of the seedlings ...
RAD18independent ubiquitination of
... A notable feature of rad18 cells is elevated levels of spontaneous SCE. Previously, it has been argued that this probably reflects an increased use of recombination resulting from the absence of functional post-replication repair (Yamashita et al, 2002). Therefore, on the basis of this and the data ...
... A notable feature of rad18 cells is elevated levels of spontaneous SCE. Previously, it has been argued that this probably reflects an increased use of recombination resulting from the absence of functional post-replication repair (Yamashita et al, 2002). Therefore, on the basis of this and the data ...
Lung interstitial macrophages alter dendritic Research article
... DCs. Phagocytosis was determined by flow cytometry evaluation of FITC-labeled dextran uptake. Although lung DCs were able to take up dextran, only IMs and AMs displayed strong phagocytic activity (Figure 1H). To assess their ability to induce T cell proliferation, IMs, AMs, and lung DCs were loaded ...
... DCs. Phagocytosis was determined by flow cytometry evaluation of FITC-labeled dextran uptake. Although lung DCs were able to take up dextran, only IMs and AMs displayed strong phagocytic activity (Figure 1H). To assess their ability to induce T cell proliferation, IMs, AMs, and lung DCs were loaded ...
... stimulation of T cells, which is analogous to mammalian IL-1β [17]. IL-6 is a highly pleotropic cytokine and has a significant role in both innate and adaptive immunity. In fish, it has been identified in several species, displaying structural characteristics shared with other vertebrates therefore ...
DNA vaccination
DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.