ACEMBL System:
... protein assemblies play an important role in all these biological phenomena. In addition, other processes, e.g. entry of viruses into human cells, also critically hinge on multiple proteins or protein complexes5. Moreover, various prokaryotic microorganisms, with E.coli being the prototypical workho ...
... protein assemblies play an important role in all these biological phenomena. In addition, other processes, e.g. entry of viruses into human cells, also critically hinge on multiple proteins or protein complexes5. Moreover, various prokaryotic microorganisms, with E.coli being the prototypical workho ...
Microbial Gene Transfer: An Ecological
... suggested that transformation could be a viable mechanism of gene transfer. Gene transfer to a High Frequency of Transformation Vibrio was demonstrated using plasmid multimers and seawater microcosms (Paul et al., 1991) The presence of the ambient microbial community in water column simulations eith ...
... suggested that transformation could be a viable mechanism of gene transfer. Gene transfer to a High Frequency of Transformation Vibrio was demonstrated using plasmid multimers and seawater microcosms (Paul et al., 1991) The presence of the ambient microbial community in water column simulations eith ...
Final Report
... using traditional whole mount protocols based on the colorimetric reaction by alkaline phosphatases has been elusive up to date. To troubleshoot, we tried to perform in situ hybridizations on sections of Limulus embryos. We also tried another method of in situ hybridization using fluorescent detecti ...
... using traditional whole mount protocols based on the colorimetric reaction by alkaline phosphatases has been elusive up to date. To troubleshoot, we tried to perform in situ hybridizations on sections of Limulus embryos. We also tried another method of in situ hybridization using fluorescent detecti ...
Presentation1 - Home - KSU Faculty Member websites
... • Staphylococcus aureus has been responsible for a great deal of human morbidity and mortality throughout history • The introduction of penicillin in the1940s greatly improved the prognosis for patients with severe staphylococcal infections ...
... • Staphylococcus aureus has been responsible for a great deal of human morbidity and mortality throughout history • The introduction of penicillin in the1940s greatly improved the prognosis for patients with severe staphylococcal infections ...
Rate of Gene Transfer From Mitochondria to Nucleus
... gene transfer. Nevertheless, in reality, many genes have been lost from mitochondrial genomes, the nuclear copies instead being active in these species. Such a strong selective force for gene transfer cannot be explained by Muller’s ratchet only (Blanchard and Lynch 2000). Another hypothesis of gene ...
... gene transfer. Nevertheless, in reality, many genes have been lost from mitochondrial genomes, the nuclear copies instead being active in these species. Such a strong selective force for gene transfer cannot be explained by Muller’s ratchet only (Blanchard and Lynch 2000). Another hypothesis of gene ...
H4K20me1 Contributes to Downregulation of X
... The Caenorhabditis elegans dosage compensation complex (DCC) equalizes X-chromosome gene dosage between XO males and XX hermaphrodites by two-fold repression of X-linked gene expression in hermaphrodites. The DCC localizes to the X chromosomes in hermaphrodites but not in males, and some subunits fo ...
... The Caenorhabditis elegans dosage compensation complex (DCC) equalizes X-chromosome gene dosage between XO males and XX hermaphrodites by two-fold repression of X-linked gene expression in hermaphrodites. The DCC localizes to the X chromosomes in hermaphrodites but not in males, and some subunits fo ...
SERK and APOSTART. Candidate Genes for
... nucleotides (accession no. AJ841698). Genomic sequencing of PpSERK1 showed that it is 5,188 nucleotides in length and contains 11 exons and 10 introns with a conserved exon/intron structure (supplemental data) identified in other SERK genes (Nolan et al., 2003). PpSERK2 is 2,246 nucleotides in lengt ...
... nucleotides (accession no. AJ841698). Genomic sequencing of PpSERK1 showed that it is 5,188 nucleotides in length and contains 11 exons and 10 introns with a conserved exon/intron structure (supplemental data) identified in other SERK genes (Nolan et al., 2003). PpSERK2 is 2,246 nucleotides in lengt ...
Microdeletions on the long arm of the Y chromosome
... arms of the Y chromosome. The multicopy nature of RBMY1A1 has made it difficult to assign the gene with a specific function in spermatogenesis.48 An immunohistochemical study has shown that the RBMY1A1 protein is localised in the nucleus of human male germ cells, specifically to the AZFb region of t ...
... arms of the Y chromosome. The multicopy nature of RBMY1A1 has made it difficult to assign the gene with a specific function in spermatogenesis.48 An immunohistochemical study has shown that the RBMY1A1 protein is localised in the nucleus of human male germ cells, specifically to the AZFb region of t ...
Friedreich ataxia: The clinical picture
... in the CNS showed this technique to be useful in evaluating mitochondrial dysfunction. Results revealed decreases in parameters related to adenosine triphosphate (ATP) synthesis efficiency, which had been found previously in the heart and skeletal muscle of these patients [11]. However, such studies ...
... in the CNS showed this technique to be useful in evaluating mitochondrial dysfunction. Results revealed decreases in parameters related to adenosine triphosphate (ATP) synthesis efficiency, which had been found previously in the heart and skeletal muscle of these patients [11]. However, such studies ...
LOSS OF HETEROZYGOSITY DUE TO SHORT-TRACT AND LONG-TRACT SACCHAROMYCES CEREVISIAE Thomas Coates
... Hotspots for genetic alterations are of particular importance in the development of cancers. Common fragile sites are a highly conserved part of the human genome, present in all individuals and prone to breakage when a cell is under replication stress. They are regions prone to breaking under replic ...
... Hotspots for genetic alterations are of particular importance in the development of cancers. Common fragile sites are a highly conserved part of the human genome, present in all individuals and prone to breakage when a cell is under replication stress. They are regions prone to breaking under replic ...
Multiple Testing Corrections
... correct for occurrence of false positives. In microarray data analysis, false positives are genes that are found to be statistically different between conditions, but are not in reality. B. Importance of Multiple testing corrections A typical microarray experiment measures several thousand genes sim ...
... correct for occurrence of false positives. In microarray data analysis, false positives are genes that are found to be statistically different between conditions, but are not in reality. B. Importance of Multiple testing corrections A typical microarray experiment measures several thousand genes sim ...
Identifying genetic susceptibility factors for
... infected with Mycobacterium tuberculosis, but that only one in ten of those infected ever develop clinical disease [1,2]. There are many well known risk factors for tuberculosis, including HIV infection, advanced age, malnutrition, alcohol abuse, diabetes and corticosteroids. ...
... infected with Mycobacterium tuberculosis, but that only one in ten of those infected ever develop clinical disease [1,2]. There are many well known risk factors for tuberculosis, including HIV infection, advanced age, malnutrition, alcohol abuse, diabetes and corticosteroids. ...
The molecular basis of cytoplasmic male sterility and
... Cytoplasmic male sterility (CMS) is a maternally inherited condition in which a plant is unable to produce functional pollen. It occurs in many plant species and is often associated with chimeric mitochondrial open reading frames. In a number of cases, transcripts originating from these altered open ...
... Cytoplasmic male sterility (CMS) is a maternally inherited condition in which a plant is unable to produce functional pollen. It occurs in many plant species and is often associated with chimeric mitochondrial open reading frames. In a number of cases, transcripts originating from these altered open ...
Ehlers-Danlos Syndrome
... b. Demonstration of a mutation in the COL3A1 gene c. Surveillance of aneurysm by MRI or CT scan without contrast material or venous subtraction angiography 3. Kyphoscoliosis type a. Demonstration of deficient activity of the enzyme procollagen lysine hydroxylase in affected individuals, diagnosed by ...
... b. Demonstration of a mutation in the COL3A1 gene c. Surveillance of aneurysm by MRI or CT scan without contrast material or venous subtraction angiography 3. Kyphoscoliosis type a. Demonstration of deficient activity of the enzyme procollagen lysine hydroxylase in affected individuals, diagnosed by ...
Doubling Down on Genomes: Polyploidy and Crop Plants
... changes accompanying allopolyploidy. Thus, differences between the allopolyploids and progenitors were not due to intraspecific differences within the ancestral species, but occurred immediately subsequent to polyploid formation. Genetic alterations were observed in all five of the resulting generat ...
... changes accompanying allopolyploidy. Thus, differences between the allopolyploids and progenitors were not due to intraspecific differences within the ancestral species, but occurred immediately subsequent to polyploid formation. Genetic alterations were observed in all five of the resulting generat ...
Knockdown of Parhyale Ultrabithorax - IMBB
... injections and that 3 unique PhUbx siRNAs individually produce the same phenotypes suggests our transformations result from specifically knocking down PhUbx function. We also immunostained PhUbx siRNA-injected embryos at stage 23 and found that PhUbx protein levels were clearly reduced, although not ...
... injections and that 3 unique PhUbx siRNAs individually produce the same phenotypes suggests our transformations result from specifically knocking down PhUbx function. We also immunostained PhUbx siRNA-injected embryos at stage 23 and found that PhUbx protein levels were clearly reduced, although not ...
A Novel CpG Island Set Identifies Tissue-Specific
... human genome, which accords with the adjusted CGI library estimate of 25,200. The coincidence of these numbers masks significant differences, however, as 23% of CGIs in the library are not detected by the NCBI-strict algorithm (4,082 out of 17,387; Table 1). Four randomly selected examples of library ...
... human genome, which accords with the adjusted CGI library estimate of 25,200. The coincidence of these numbers masks significant differences, however, as 23% of CGIs in the library are not detected by the NCBI-strict algorithm (4,082 out of 17,387; Table 1). Four randomly selected examples of library ...
Transition bias and substitution models
... Histone deacetylases: deacetylate lysyl residues in histones (the half life of an acetyl group is ~10min). Acetylation removes a positive charge on the lysine amino group and promote nucleosome melting (and gene expression). Deacetylation tend to decrease or turn off gene expression. ...
... Histone deacetylases: deacetylate lysyl residues in histones (the half life of an acetyl group is ~10min). Acetylation removes a positive charge on the lysine amino group and promote nucleosome melting (and gene expression). Deacetylation tend to decrease or turn off gene expression. ...
Cavy Genetics - British Cavy Council
... received the same allele from both parents, then it is said to be homozygous, but if it has different ones from each parent then it is said to be heterozygous. In general English usage the word gene is commonly used to mean a locus and sometimes an allele. This sounds like it should be confusing, b ...
... received the same allele from both parents, then it is said to be homozygous, but if it has different ones from each parent then it is said to be heterozygous. In general English usage the word gene is commonly used to mean a locus and sometimes an allele. This sounds like it should be confusing, b ...
Characterization of the neurohypophysial hormone gene loci in
... differences in the organization of the vasopressin- and oxytocin-family genes in different bony vertebrate lineages raise questions about their origin and the organization of the ancestral vasopressin-family and oxytocinfamily genes. The cartilaginous fishes are the oldest group of living jawed vert ...
... differences in the organization of the vasopressin- and oxytocin-family genes in different bony vertebrate lineages raise questions about their origin and the organization of the ancestral vasopressin-family and oxytocinfamily genes. The cartilaginous fishes are the oldest group of living jawed vert ...
Leukaemia Section 3q27 rearrangements in non Hodgkin lymphoma,
... immunoblasts or of anaplastic B-cells were put forward but were felt not to be enough reproducible as to allow for proper categorization of distinct pathological entities; 3q27 abnormalities were seen in similar frequency in the immunoblastic variant and in the centroblastic variant of DLCL in a stu ...
... immunoblasts or of anaplastic B-cells were put forward but were felt not to be enough reproducible as to allow for proper categorization of distinct pathological entities; 3q27 abnormalities were seen in similar frequency in the immunoblastic variant and in the centroblastic variant of DLCL in a stu ...
Evolution of RH Genes in Hominoids: Characterization of a Gorilla
... cDNA of gorilla Kessala from exon 1 to exon 4 failed. A coding sequence was deduced from the Kessala genomic exon 4 and from Kessala’s RHCE-like cDNA. This gorilla RHCElike coding sequence (exon 4 to 10) was aligned to human and primate Rh cDNA sequences ( Figure 2). Gorilla RHCE-like cDNA differs f ...
... cDNA of gorilla Kessala from exon 1 to exon 4 failed. A coding sequence was deduced from the Kessala genomic exon 4 and from Kessala’s RHCE-like cDNA. This gorilla RHCElike coding sequence (exon 4 to 10) was aligned to human and primate Rh cDNA sequences ( Figure 2). Gorilla RHCE-like cDNA differs f ...
Microarray Data Analysis Using R Bioconductor
... Introduction to Bioconductor • R Bioconductor：http://www.bioconductor.org – The Bioconductor project started in 2001 and is overseen by a core team, based primarily at the Fred Hutchinson Cancer Research Center, and by other members coming from US and international institutions. – It gained widespr ...
... Introduction to Bioconductor • R Bioconductor：http://www.bioconductor.org – The Bioconductor project started in 2001 and is overseen by a core team, based primarily at the Fred Hutchinson Cancer Research Center, and by other members coming from US and international institutions. – It gained widespr ...
Ectopic segmentation gene expression and
... anterior or posterior edges (Fig. 4,A.). The staining is neither segmental nor parasegmental, and both parasegments contribute to the fused metamere. Thus, the parasegmental deletions in heat-shocked HSF embryos are misleading. They do not reflect the loss of a parasegmental metamere, but rather its ...
... anterior or posterior edges (Fig. 4,A.). The staining is neither segmental nor parasegmental, and both parasegments contribute to the fused metamere. Thus, the parasegmental deletions in heat-shocked HSF embryos are misleading. They do not reflect the loss of a parasegmental metamere, but rather its ...
Ribosome stalls at trp codons, allowing 2+3 pairing Transcription
... DNA (cis) or on a separate piece of DNA (trans). ...
... DNA (cis) or on a separate piece of DNA (trans). ...