Phevor Combines Multiple Biomedical Ontologies for
... example, annotating a gene with the term ‘‘deaminase activity’’ makes it possible to deduce that the same gene encodes a protein with ‘‘catalytic activity.’’ In recent years, many biomedical ontologies have been created for the management of biological data.15–17 Phevor propagates an individual’s ph ...
... example, annotating a gene with the term ‘‘deaminase activity’’ makes it possible to deduce that the same gene encodes a protein with ‘‘catalytic activity.’’ In recent years, many biomedical ontologies have been created for the management of biological data.15–17 Phevor propagates an individual’s ph ...
We need an optimality criterion to choose a best estimate (tree
... least amount of change along its branches to produce the data. ...
... least amount of change along its branches to produce the data. ...
Transgenic approaches to microbial disease resistance in crop
... number of these genes has shown that R-gene products share motifs such as leucine-rich repeats (LRRs), nucleotide binding sites, and kinase domains, consistent with their roles in signaling pathways and suggesting common mechanisms for pathogen recognition which might be exploited for applied goals ...
... number of these genes has shown that R-gene products share motifs such as leucine-rich repeats (LRRs), nucleotide binding sites, and kinase domains, consistent with their roles in signaling pathways and suggesting common mechanisms for pathogen recognition which might be exploited for applied goals ...
a hint of the same genetic defect as in Fechtner syndrome
... A gene that affects platelet biogenesis is more attractive. That this candidate gene is sometimes involved in tissue alterations may be explained, for example, by mutations that lead to deleterious accumulation of the mutated protein in renal epithelial cells, lens capsule, or inner ear and in megak ...
... A gene that affects platelet biogenesis is more attractive. That this candidate gene is sometimes involved in tissue alterations may be explained, for example, by mutations that lead to deleterious accumulation of the mutated protein in renal epithelial cells, lens capsule, or inner ear and in megak ...
Conspiracy of silence among repeated transgenes
... as few as 3 copies showed PEV-like phenotypes.(9) Furthermore, the frequency of silencing increased with copy number. Copy number-dependent silencing was seen for tandem arrays, although reversals in orientation increased the degree of silencing, supporting the idea underlying Pontecorvo’s conjectur ...
... as few as 3 copies showed PEV-like phenotypes.(9) Furthermore, the frequency of silencing increased with copy number. Copy number-dependent silencing was seen for tandem arrays, although reversals in orientation increased the degree of silencing, supporting the idea underlying Pontecorvo’s conjectur ...
Algorithm to extract REP sequences Pattern
... III. Determination of short tandem repeats (STRs) IV. Analysis of gene expression data ...
... III. Determination of short tandem repeats (STRs) IV. Analysis of gene expression data ...
Presentation: Computation to Solve Problems
... III. Determination of short tandem repeats (STRs) IV. Analysis of gene expression data ...
... III. Determination of short tandem repeats (STRs) IV. Analysis of gene expression data ...
RNAi in Plants: An Argonaute-Centered View
... compartments. The deficiency of isoprenoids synthesis, which is essential for a variety of pathways including the production of membrane sterols, impairs miRNA-mediated cleavage of at least some target transcripts, suggesting that membrane association of AGO1 is important for mRNA cleavage (Brodersen ...
... compartments. The deficiency of isoprenoids synthesis, which is essential for a variety of pathways including the production of membrane sterols, impairs miRNA-mediated cleavage of at least some target transcripts, suggesting that membrane association of AGO1 is important for mRNA cleavage (Brodersen ...
The Association of DRD2 Gene TaqI Polymorphism with Attention
... confirms the role of the dopamine neurotransmitter system in the etiology of ADHD, studies of molecular genetic have mostly focused on genes in these pathways. Because dopamine is involved in a variety of critical functions, therefore many human disorders have been related to dopaminergic dysfunctio ...
... confirms the role of the dopamine neurotransmitter system in the etiology of ADHD, studies of molecular genetic have mostly focused on genes in these pathways. Because dopamine is involved in a variety of critical functions, therefore many human disorders have been related to dopaminergic dysfunctio ...
Amplified fragment length polymorphism (AFLP)
... losses were estimated respectively at 36% and 32% for bread wheat (Triticum aestivum L.) and durum wheat (T. durum Desf.) (Amri et al., 1992a; Lhaloui et al., 1992). Moreover, high damages, even total crop losses can be observed if high infestations occur at early developmental stages (Amri et al., ...
... losses were estimated respectively at 36% and 32% for bread wheat (Triticum aestivum L.) and durum wheat (T. durum Desf.) (Amri et al., 1992a; Lhaloui et al., 1992). Moreover, high damages, even total crop losses can be observed if high infestations occur at early developmental stages (Amri et al., ...
Changes in Plasma Low-Density Lipoprotein (LDL)
... The variable extent of the changes in LDL-C and HDL-C, upon restoration of the euthyroid state in hypothyroid patients, as observed in clinical practice, existed also in our patients. Changes in LDL-C were, however, not associated with the AvaII polymorphism. This is in contrast with the results of ...
... The variable extent of the changes in LDL-C and HDL-C, upon restoration of the euthyroid state in hypothyroid patients, as observed in clinical practice, existed also in our patients. Changes in LDL-C were, however, not associated with the AvaII polymorphism. This is in contrast with the results of ...
Sarah Pulliam
... both young and old mice. Blasco et al. concluded that the s-Arf/p53 mice live longer due to an antioxidant affect created when both the Arf and p53 genes are over expressed at the same time. In another study, Pinkston, et al. found the same results in Caenorhabditis elegans, a nematode worm. Just a ...
... both young and old mice. Blasco et al. concluded that the s-Arf/p53 mice live longer due to an antioxidant affect created when both the Arf and p53 genes are over expressed at the same time. In another study, Pinkston, et al. found the same results in Caenorhabditis elegans, a nematode worm. Just a ...
The Birth- and- Death Evolution of Multigene Families Revisited
... orthologous-paralogous gene relationships [4]. Gene families can be classified according to a number of criteria [3, 5, 6]. Such criteria may include, for example, (1) function, (2) how members are distributed across the genome, and (3) the primary mechanism responsible for generating the families i ...
... orthologous-paralogous gene relationships [4]. Gene families can be classified according to a number of criteria [3, 5, 6]. Such criteria may include, for example, (1) function, (2) how members are distributed across the genome, and (3) the primary mechanism responsible for generating the families i ...
Bridging the transgenerational gap with epigenetic memory
... members of the COMPASS complex, because manipulation of other longevity-promoting pathways, such as the insulin signaling and mitochondrial pathways, or other chromatin regulators, did not show a transgenerational inheritance of long life [27]. These findings show that manipulation of specific chrom ...
... members of the COMPASS complex, because manipulation of other longevity-promoting pathways, such as the insulin signaling and mitochondrial pathways, or other chromatin regulators, did not show a transgenerational inheritance of long life [27]. These findings show that manipulation of specific chrom ...
Phenotype and gene ontology enrichment as guides for
... (GO), which provides a controlled language to describe molecular and cellular functions of genes [3]. In C. elegans, gene, tissue and phenotype ontologies exist with which to describe C. elegans anatomy and phenotypes respectively [5, 6]. These ontologies are curated by professional curators at Worm ...
... (GO), which provides a controlled language to describe molecular and cellular functions of genes [3]. In C. elegans, gene, tissue and phenotype ontologies exist with which to describe C. elegans anatomy and phenotypes respectively [5, 6]. These ontologies are curated by professional curators at Worm ...
DFL1, an auxin-responsive GH3 gene homologue, negatively
... multiple auxin-responsive elements, 5¢-GTGCTC-3¢ (Liu et al., 1994). In the promoter region of the DFL1 gene there is also a potential auxin-responsive element, 5¢GTGCAC-3¢. To determine whether DFL1 gene expression is also induced by auxin, we compared the accumulation of the transcript in the wild ...
... multiple auxin-responsive elements, 5¢-GTGCTC-3¢ (Liu et al., 1994). In the promoter region of the DFL1 gene there is also a potential auxin-responsive element, 5¢GTGCAC-3¢. To determine whether DFL1 gene expression is also induced by auxin, we compared the accumulation of the transcript in the wild ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... As the recurrence risk is 25%, chorionic villus sampling at 9-12 weeks is recommended for prenatal diagnosis in at-risk patients. The prognosis is poor. Most patients succumb in the second or third decade of life due to complications related to diabetes, atherosclerosis or chronic liver failure. ...
... As the recurrence risk is 25%, chorionic villus sampling at 9-12 weeks is recommended for prenatal diagnosis in at-risk patients. The prognosis is poor. Most patients succumb in the second or third decade of life due to complications related to diabetes, atherosclerosis or chronic liver failure. ...
Red Line Walk-through
... sequences that appear to come from the same transcription locus (gene or expressed pseudogene), together with information on protein similarities, gene expression, cDNA clone reagents, and genomic location.” http://www.ncbi.nlm.nih.gov/u nigene cDNA: DNA produced by reverse transcribing mRNA using r ...
... sequences that appear to come from the same transcription locus (gene or expressed pseudogene), together with information on protein similarities, gene expression, cDNA clone reagents, and genomic location.” http://www.ncbi.nlm.nih.gov/u nigene cDNA: DNA produced by reverse transcribing mRNA using r ...
Parent organism - Office of the Gene Technology Regulator
... RR Flex/Bollgard II® cotton plants. This gene encodes the enzyme -glucuronidase (GUS) that enables visual identification of plant tissues in which it is being expressed. Short regulatory sequences that control expression of the genes are also present in the genetically modified cottons. These seque ...
... RR Flex/Bollgard II® cotton plants. This gene encodes the enzyme -glucuronidase (GUS) that enables visual identification of plant tissues in which it is being expressed. Short regulatory sequences that control expression of the genes are also present in the genetically modified cottons. These seque ...
as a PDF
... reported that the allele frequency of V647G variation in the human Per3 gene was significantly higher in DSPS patients compared with normal controls, indicating that the variation acts as a risk factor for DSPS (15). Although the role of the PER3 protein in circadian rhythm generation has yet to be ...
... reported that the allele frequency of V647G variation in the human Per3 gene was significantly higher in DSPS patients compared with normal controls, indicating that the variation acts as a risk factor for DSPS (15). Although the role of the PER3 protein in circadian rhythm generation has yet to be ...
Comparative analysis of mono(2-ethylhexyl)phthalate (MEHP) and
... recently demonstrated to disturb fat cell energy metabolism; however, the underlying mechanism remained unclear. The study aimed to determine how MEHP influenced fat cell transcriptome and how the changes might contribute to bioenergetics. Because of the pivotal role of PPARγ in energy metabolism of ...
... recently demonstrated to disturb fat cell energy metabolism; however, the underlying mechanism remained unclear. The study aimed to determine how MEHP influenced fat cell transcriptome and how the changes might contribute to bioenergetics. Because of the pivotal role of PPARγ in energy metabolism of ...
Ends-out, or replacement, gene targeting in Drosophila
... the same as those used for ends-in targeting: heat-inducible FLP recombinase (13) and I-SceI endonuclease (3) transgenes (70FLP and 70I-SceI). We also constructed donor transgenes that carry sequence from the locus to be targeted. We first made and transformed a y⫹ P element donor construct to rescu ...
... the same as those used for ends-in targeting: heat-inducible FLP recombinase (13) and I-SceI endonuclease (3) transgenes (70FLP and 70I-SceI). We also constructed donor transgenes that carry sequence from the locus to be targeted. We first made and transformed a y⫹ P element donor construct to rescu ...
The ECF sigma factors of Streptomyces coelicolor A3(2)
... included certain -lactam antibiotics and, most effectively, glycopeptide antibiotics such as vancomycin and teicoplanin. ‘Negative control’ antibiotics that target the ribosome (e.g. thiostrepton, streptomycin) or DNA gyrase (novobiocin) did not induce sigE expression. In addition to antibiotics, l ...
... included certain -lactam antibiotics and, most effectively, glycopeptide antibiotics such as vancomycin and teicoplanin. ‘Negative control’ antibiotics that target the ribosome (e.g. thiostrepton, streptomycin) or DNA gyrase (novobiocin) did not induce sigE expression. In addition to antibiotics, l ...
Gene Section CDA (Cytidine Deaminase) Atlas of Genetics and Cytogenetics
... (Lys27Gln) and 208G>A (Ala70Thr), have been found in the human CDA gene (Yue et al., 2003). Ethnic differences in the minor allele frequencies of these variations have been reported. The 79A>C (Lys27Gln) was found at 0.30-0.36 frequencies in Caucasians, at 0.20-0.21 in Japanese and at 0.04-0.10 in A ...
... (Lys27Gln) and 208G>A (Ala70Thr), have been found in the human CDA gene (Yue et al., 2003). Ethnic differences in the minor allele frequencies of these variations have been reported. The 79A>C (Lys27Gln) was found at 0.30-0.36 frequencies in Caucasians, at 0.20-0.21 in Japanese and at 0.04-0.10 in A ...